Publications
Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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a point mutation in influenza b neuraminidase confers resistance to peramivir and loss of slow binding. | the influenza neuraminidase (na) inhibitors peramivir, oseltamivir, and zanamivir are potent inhibitors of nas from both influenza a and b strains. in general, these inhibitors are slow, tight binders of na, exhibiting time-dependent inhibition. a mutant of influenza virus b/yamagata/16/88 which was resistant to peramivir was generated by passage of the virus in tissue culture, in the presence of increasing concentrations (0.1-120 microm over 15 passages) of the compound. whereas the wild type ( ... | 2003 | 12834856 |
antiviral activity of inonotus hispidus. | the antiviral activity of two phenolic compounds, hispolon and hispidin, isolated from the fruit bodies of the basidiomycete inonotus hispidus as well as of some extracts prepared from fruit bodies and mycelial cultures of this fungus was investigated in allantois on the shell-test system. ethanolic extracts, hispidin and hispolon showed considerable antiviral activity against influenza viruses type a and b. | 2003 | 12837367 |
polysaccharide antibody responses are impaired post bone marrow transplantation for severe combined immunodeficiency, but not other primary immunodeficiencies. | established treatment of severe combined immunodeficiencies (scid) and other primary immunodeficiencies (pid) is bone marrow transplantation (bmt). normal lymphocyte numbers and protein antigen responses are present within 2 years of bmt, polysaccharide antibody responses appear last. streptococcus pneumoniae infection causes significant morbidity and mortality post-bmt. previous studies have shown good protein antigen responses post-bmt for scid and pid, but had not examined the polysaccharide ... | 2003 | 12838289 |
suboptimal detection of influenza virus in adults by the directigen flu a+b enzyme immunoassay and correlation of results with the number of antigen-positive cells detected by cytospin immunofluorescence. | to provide 24-h influenza diagnosis for adults presenting to the emergency department, the directigen flu a+b enzyme immunoassay (eia) was performed in the chemistry laboratory during the night shift. nasopharyngeal swabs were retested by cytospin-enhanced direct immunofluorescence (dfa; simulfluor respiratory screen) when the virology laboratory opened. the influenza eia detected 16 influenza a virus infections, whereas cytospin-enhanced dfa detected 31 influenza a virus infections as well as 3 ... | 2003 | 12843105 |
influenza b virus bm2 protein has ion channel activity that conducts protons across membranes. | successful uncoating of the influenza b virus in endosomes is predicted to require acidification of the interior of the virus particle. we report that a virion component, the bm2 integral membrane protein, when expressed in xenopus oocytes or in mammalian cells, causes acidification of the cells and possesses ion channel activity consistent with proton conduction. furthermore, coexpression of bm2 with hemagglutinin (ha) glycoprotein prevents ha from adopting its low-ph-induced conformation durin ... | 2003 | 12852861 |
production and characterization of a human recombinant monoclonal fab fragment specific for influenza a viruses. | a human recombinant monoclonal fab fragment that specifically recognizes all the influenza a virus strains tested was produced in transformed escherichia coli using the phage display technique. no strain of influenza b virus reacted with it. it was purified after four cycles of panning and by a single passage through an immunoaffinity column. about 1 mg of pure monoclonal antibody was obtained from 1 liter of culture medium in 3 working days. the fab fragment reacted with a viral 27-kda protein, ... | 2003 | 12853404 |
neuraminidase inhibitors for influenza a and b: study showed benefits of treatment are marginal. | 2003 | 12855537 | |
neuraminidase inhibitors for influenza a and b: antivirals need to be protected from adverse conditions to retain effectiveness. | 2003 | 12855538 | |
neuraminidase inhibitors for influenza a and b: prose may be as useful as poems. | 2003 | 12855540 | |
winter respiratory viruses and health care use: a population-based study in the northwest united states. | to quantify health care use among adults during influenza and respiratory syncytial virus (rsv) seasons, we identified a cohort of veterans aged >or=18 years who used department of veterans affairs (va) facilities in oregon and washington states as their source of health care. during 1998-2000, veterans accrued 237,159 person-years of follow-up. using va data sources, we measured acute cardiopulmonary hospitalizations and primary care and urgent care visits. differences between rates of study ev ... | 2003 | 12856212 |
respiratory tract viral infections in bone marrow transplant patients. | community respiratory viruses such as respiratory syncytial virus (rsv), adenovirus, influenza a, influenza b, and the parainfluenza group are frequent causes of respiratory disease in bone marrow transplant (bmt) patients. | 2003 | 12865800 |
[antigenic and genetic characterizations of victoria like strain of influenza b viruses isolated in china in 2001]. | to understand the antigenic and genetic characteristics of victoria like strain of influenza b virus isolated recently and to provide a scientific evidence for influenza surveillance and monitoring of influenza epidemic in future. | 2003 | 12870010 |
a randomized controlled trial comparing split and subunit influenza vaccines in adults in colombia. | in a two-center, comparative trial, 344 adults were randomly assigned to receive a single dose of inactivated split-virion (imovax gripe) or sub-unit (agrippal s1) influenza vaccine (1999-2000 formulations). for analysis, study groups were subdivided into adult (18-60 years old) and elderly (over 60 years) subjects. blood was drawn immediately before and one month after vaccination, safety was evaluated using a blind-observer design based on reporting of solicited and unsolicited adverse events. ... | 2003 | 12876902 |
influenza b acute necrotizing encephalopathy: a case report and literature review. | the case of a 9-year-old girl with acute encephalopathy with evidence of influenza b virus infection and bilateral basal ganglia lesions is reported. the literature on acute necrotizing encephalopathy is reviewed, and other causes of bilateral basal ganglia lesions are discussed. | 2003 | 12878304 |
impact of oseltamivir treatment on influenza-related lower respiratory tract complications and hospitalizations. | influenza causes lower respiratory tract complications (lrtcs), particularly bronchitis and pneumonia, in both otherwise healthy adults and those with underlying conditions. the aim of this study was to assess the effect of oseltamivir treatment on the incidence of lrtcs leading to antibiotic treatment and hospitalizations following influenza illness. | 2003 | 12885681 |
[differences in oligomerization of nucleocapsid protein of epidemic human influenza a(h1n1), a(h1n2) and b viruses]. | a comparative analysis of involving the nucleocapsid protein (np) into shaping-up of sds-resistant oligomers was carried out presently in circulating epidemic strains of human influenza, viruses a and b. the study results of viral isolates obtained from clinical samples and recent standard strains revealed that the involvement of np in the sds-resistant oligomers, which are different in various subtypes of influenza a viruses. according to this sign, the human viruses a(9h3n2) are close to the a ... | 2003 | 12894477 |
comparison of the directigen flu a+b test, the quickvue influenza test, and clinical case definition to viral culture and reverse transcription-pcr for rapid diagnosis of influenza virus infection. | the diagnostic performances of the clinical case definition of influenza virus infection based on the combination of fever and cough and of two rapid influenza diagnostic tests, the directigen flu a+b test (directigen; bd diagnostic systems, sparks, md.) and the quickvue influenza test (quickvue; quidel, san diego, calif.), were compared to those of viral culture and an in-house reverse transcription (rt)-pcr during the 2000-2001 flu season. two hundred consecutive nasopharyngeal aspirates were ... | 2003 | 12904343 |
estimating efficacy of trivalent, cold-adapted, influenza virus vaccine (caiv-t) against influenza a (h1n1) and b using surveillance cultures. | the authors report on a community-based, nonrandomized, open-label study, conducted during the 2000-2001 influenza season in temple-belton, texas, of the protective effectiveness of trivalent, cold-adapted, influenza virus vaccine (caiv-t) in children aged 18 months-18 years. the dominant circulating strains in 2000-2001 were influenza a/new caledonia/20/99 (h1n1) and influenza b/sichuan/379/99. children had access to caiv-t during the 1998-1999, 1999-2000, and 2000-2001 influenza seasons. the v ... | 2003 | 12915495 |
chimeric influenza a viruses with a functional influenza b virus neuraminidase or hemagglutinin. | reassortment of influenza a and b viruses has never been observed in vivo or in vitro. using reverse genetics techniques, we generated recombinant influenza a/wsn/33 (wsn) viruses carrying the neuraminidase (na) of influenza b virus. chimeric viruses expressing the full-length influenza b/yamagata/16/88 virus na grew to titers similar to that of wild-type influenza wsn virus. recombinant viruses in which the cytoplasmic tail or the cytoplasmic tail and the transmembrane domain of the type b na w ... | 2003 | 12915528 |
genetic and phenotypic analysis of reassortants of high growth and low growth strains of influenza b virus. | the yield of influenza virus in eggs is critical to influenza vaccine production and availability, but the contribution of specific genes to the growth properties of influenza b viruses is not well understood. influenza b/beijing/184/93 and b/shangdong/7/97 were chosen for study because b/shangdong/7/97 replicated to several fold higher titers in eggs than b/beijing/184/93 as demonstrated by hemagglutination titers and eid50. a reassortant with the ha, np and pb2 genes from b/beijing/184/93 and ... | 2003 | 12922121 |
[development of a live culture of cold-adapted reassortant influenza vaccines]. | optimal conditions for the cultivation of the mdck cell lines in the laboratory spinner or by using the eagle-mem with or without fetal serum were worked out. the cold-adapted reassortant vaccine strains of virus influenza a/h1n1, a/h3n2 and b are well replicated in the mdck cells both in a monolayer and in the spinner by using the serum-free medium. a maximum virus titer depends on a multiplicity of infection used in a fetal medium and on the addition of trypsin. under the optimal conditions, t ... | 2003 | 12924092 |
[influenza in poland in 2001]. | in 2001 the number of cases of influenza and influenza-like illness (ili) registered in poland amounted to 576,449. this is 36.1% of the number of cases recorded in 2000. the highest influenza incidence was found in dolnoślaskie voivodship (3013.4 per 100,000), mazowieckie voivodship (2688.5 per 100,000) and zachodniopomorskie voivodship (2132.2 per 100,000). in children aged 0 to 14 years the number of influenza and ili cases amounted to 275,358 (incidence was 3851.4 per 100,000) and this is 47 ... | 2003 | 12926309 |
annual report of the national influenza surveillance scheme, 2002. | surveillance for influenza in australia in 2002 was based on notifications to the national notifiable diseases surveillance system from all states and territories, national and state-based sentinel practice consultations for influenza-like illness and reports of influenza virus isolations from a laboratory network. the impact of influenza was assessed by absenteeism data from a major national employer. influenza a was the dominant type, 99 per cent of which were subtype h3n2 with only a single h ... | 2003 | 12926731 |
rapid detection of influenza a and b viruses in clinical specimens by light cycler real time rt-pcr. | the influenza viruses cause morbidity and mortality annually among children and elderly. surveillance and rapid diagnosis is imperative in the reference laboratory, as clinical symptoms are insufficient for proper diagnosis. | 2003 | 12927751 |
systemic cytokine responses in patients with influenza-associated encephalopathy. | influenza-associated encephalopathy, a severe neurologic complication of influenza, is being reported more frequently in japan. we investigated the transcription of cytokine genes in peripheral blood leukocytes and compared patients with influenza and with encephalopathy or febrile convulsions and patients with influenza but without neurologic complications. a quantitative polymerase chain reaction (pcr) revealed that transcription of the interleukin (il)-6, il-10, and tumor necrosis factor-alph ... | 2003 | 12934185 |
[spread and properties of epidemic influenza a and b virus strains accountable for morbidity in russia during 1999-2002]. | the strains of influenza a -a(h1n1), a(h3n2) and b viruses were shown in the paper to have been circulating in russia in 1999-2002. a co-circulation of viruses of 2 to 3 types was detected in all epidemic seasons. a majority of strains was isolated on the culture of cells mdck. a study of epidemic strains revealed the predominance of viruses a(h3n2) in 1999-2000, the predominance of viruses a(h1n1) in 2000-2001, and the predominance of influenza b viruses in 2001-2002. according to the conducted ... | 2003 | 12945200 |
antigenic and genomic relation between human influenza viruses that circulated in argentina in the period 1995-1999 and the corresponding vaccine components. | the analysis of epidemic influenza virus has been focused on antigenic and genomic characterization of the hemagglutinin (ha) glycoprotein in order to detect new variants for the recommendation of the vaccine strains in each season. since october 1998, who organized a second meeting to evaluate the vaccine formula for the southern hemisphere. | 2003 | 12957183 |
genescan reverse transcription-pcr assay for detection of six common respiratory viruses in young children hospitalized with acute respiratory illness. | a reverse transcription-pcr (rt-pcr) assay based on automated fluorescent capillary electrophoresis and genescan software analysis was developed to detect six common respiratory viruses in clinical specimens from young children. assays for human respiratory syncytial virus (hrsv); human parainfluenza viruses 1, 2, and 3 (hpiv1, -2, and -3, respectively); and influenza a and b viruses were incorporated into a single standard assay format. the optimized assay panel was used to test 470 respiratory ... | 2003 | 12958260 |
hla class ii-restricted cd4+ t cell responses directed against influenza viral antigens postinfluenza vaccination. | the memory t cell response is polyclonal, with the magnitude and specificity of the response controlled in part by the burst size of t cells expanded from effector/memory precursors. sensitive assays using hla class ii multimers were used to detect low-frequency ag-specific t cells directed against influenza viral ags in subjects immunized with the influenza vaccine. direct ex vivo tetramer staining of pbmc from five individuals identified frequencies of hemagglutinin (ha) 306-318 tetramer bindi ... | 2003 | 12960344 |
crystal structure of the m1 protein-binding domain of the influenza a virus nuclear export protein (nep/ns2). | during influenza virus infection, viral ribonucleoproteins (vrnps) are replicated in the nucleus and must be exported to the cytoplasm before assembling into mature viral particles. nuclear export is mediated by the cellular protein crm1 and putatively by the viral protein nep/ns2. proteolytic cleavage of nep defines an n-terminal domain which mediates rangtp-dependent binding to crm1 and a c-terminal domain which binds to the viral matrix protein m1. the 2.6 a crystal structure of the c-termina ... | 2003 | 12970177 |
organization and expression strategy of the ambisense genome of densonucleosis virus of galleria mellonella. | the expression strategy of parvoviruses of the densovirus genus has as yet not been reported. clones were obtained from the densonucleosis virus of galleria mellonella (gmdnv) that yielded infectious virus upon transfection into ld652 cells. its genome was found to be the longest (6,039 nucleotides [nt]), with the largest inverted terminal repeats (itrs) (550 nt) among all parvoviruses. the distal 136 nt could be folded into hairpins with flop or flip sequence orientations. in contrast to verteb ... | 2003 | 12970420 |
influenza b virus bm2 protein is transported through the trans-golgi network as an integral membrane protein. | a bicistronic mrna transcribed from the influenza b virus rna segment 7 encodes two viral proteins, matrix protein m1 and uncharacterized small protein bm2. in the present study, we focused on the cytoplasmic transport and cellular membrane association of bm2. immunofluorescence studies of virus-infected cells indicated that bm2 accumulated at the golgi apparatus immediately after synthesis and then was transported to the plasma membrane through the trans-golgi network. localization of a set of ... | 2003 | 12970447 |
isolation and identification of influenza virus strains circulating in thailand in 2001. | local influenza surveillance plays an important role in preparing for, and responding to, epidemics and pandemics. between january and december 2001, the national institute of health of thailand collected a total of 711 throat swab specimens from outpatients affected with acute respiratory symptoms from several centers throughout thailand, of which 374 were virus-positive. of these, 338 (90.4%) were positive for influenza virus by immunofluorescence testing. by hemagglutination-inhibition (hi) t ... | 2003 | 12971520 |
[comparative study on safety and immunogenicity between influenza subunit vaccine and split vaccine]. | to compare the reactogenicity and serology between influenza subunit vaccine and split vaccine. | 2003 | 12975010 |
antigenic analysis of influenza b strains isolated in 1952. | 1952 | 12997991 | |
effect of sodium monofluoroacetate on the multiplication of influenza viruses, mumps virus and pneumonia virus of mice (pvm). | sodium fluoroacetate, given after virus inoculation in doses of 3 to 4 mg. per kg. in mice or 2 mg. in chick embryos, caused only a slight delay in the multiplication of the pr8 strain of influenza a virus in the mouse lung and of pr8 or the lee strain of influenza b virus in the allantoic sac. the quantities of the compound used were sufficient to cause approximately 10 to 20 per cent mortality in mice and 100 per cent in chick embryos. the use of small virus inocula did not markedly increase t ... | 1952 | 13022848 |
[recent serological studies on the antigenic structure of influenza b strains]. | 2006 | 13028068 | |
the antigenic variation of influenza b viruses; demonstration of an antigenic spectrum by use of titer ratios. | 1953 | 13035132 | |
[influenza in florence in the winter of 1951-1952; epidemiology of influenza b]. | 1952 | 13036778 | |
epidemic influenza b and c in navy recruits during winter of 1951-52. | 1952 | 13037744 | |
in vitro effects of cortisone on multiplication of influenza b virus. | 1953 | 13037869 | |
studies on host-virus interactions in the chick embryo-influenza virus system. vii. data concerning the significance of infectivity titration end-points and the separation of clones at limiting dilutions. | equal mixtures of influenza a (pr8) and b (lee) viruses, based on predetermined id(50) values of the individual preparations, were titrated in closely spaced steps near the 50 per cent infectivity end-point. typing of the hemagglutinins found in the allantoic fluids after incubation of the eggs for 72 hours showed an approximately equal distribution between types a and b, when less than 2 id(50) of the mixed seed had been injected. with larger inocula influenza a became dominant because it repro ... | 1953 | 13069643 |
[study of focal epidemic of influenza b on the island of ischia (1951-52); virologic and serologic research]. | 1953 | 13075788 | |
an experience with vaccination against influenza b in 1952 by use of monovalent vaccine. | 1953 | 13080256 | |
the antigenic composition of the influenza virus b strains isolated during the epidemic of influenza b in the winter 1951/52 in the netherlands. | 1953 | 13080984 | |
inhibition of influenza virus multiplication by alkyl derivatives of benzimidazole. i. kinetic aspects of inhibition by 2,5-dimethylbenzimidazole as measured by infectivity titrations. | at a concentration of 0.0026 m, 2,5-dimethylbenzimidazole caused a number of alterations in the first cycle of multiplication of influenza b virus, lee strain, in chorioallantoic membrane cultures in vitro. as determined by infectivity titrations in ovo on the membrane per se, the following alterations were observed: the duration of the latent period was increased by 80 per cent. the rate of increase in titer during the incremental period was somewhat decreased. the yield of virus was decreased ... | 1953 | 13084841 |
inhibition of influenza virus multiplication by alkyl derivatives of benzimidazole. ii. measurement of inhibitory activity by hemagglutination titrations. | the activity of compounds which inhibit the multiplication of influenza virus can be measured in chorioallantoic membrane cultures in vitro by means of hemagglutination titrations on the medium. studies on the reproducibility of virus reproduction in membrane cultures have revealed the major variables which affect the results and thus have led to the development of a precise technique. under strictly controlled experimental conditions, the extent of reproduction of the virus in membrane cultures ... | 1953 | 13084842 |
inhibition of influenza virus multiplication by alkyl derivatives of benzimidazole. iii. relationship between inhibitory activity and chemical structure. | the degree of inhibition of multiplication of influenza b virus, lee strain, in membrane cultures in vitro appears to be directly related to the concentration of the inhibitory compounds used in this investigation. with each of the alkyl derivatives of benzimidazole, evidence for such a relationship was obtained in the range between 60 and 90 per cent inhibition of virus multiplication. alteration of the structure of benzimidazole by substitution of alkyl radicals at various positions in either ... | 1953 | 13084843 |
an experience with vaccination against influenza b in 1952 using monovalent vaccine. | 1953 | 13091359 | |
influenza antibodies in the population of the usa; an epidemiological investigation. | sera taken from persons of various ages in 1951 and collected from adults yearly from 1943 to 1951, inclusive, were tested by the haemagglutination-inhibition method with influenza viruses selected to represent the subgroups of each antigenic type. these were influenza a-ws (1933) and pr8 (1934); influenza a-prime-fm1 (1947) and fw-1-50 (1950); influenza b-lee (1940) and ib1 (1950); influenza c-1233 (1947). the sera tested with influenza a and b viruses were treated with cholera filtrate to remo ... | 1953 | 13094497 |
recombination studies with two influenza virus b strains. | 1953 | 13115312 | |
disruption of influenza virus; properties of degradation products of the virus particle. | 1. the hemagglutinating capacity, enzymic activity, and infectivity of several influenza viruses were destroyed by repeated freezing and thawing of dialyzed allantoic fluids containing them. 2. influenza virus degraded by freezing and thawing, by treatment with 5 m urea, or by heating at 65 degrees c. still combined with homologous antibody and was demonstrable by blocking of the hemagglutination-inhibition and virus neutralization reactions. 3. after 50 cycles of freezing and thawing, much of t ... | 1954 | 13152279 |
the stability of human complement-fixing antibodies against lymphogranuloma venereum, psittacosis, influenza a, and influenza b antigens under various conditions of storage. | 1954 | 13163563 | |
[characteristics of influenza virus b cultured in laboratory conditions]. | 1954 | 13172282 | |
epidemic of influenza b among greenlandic patients in a danish tuberculosis sanatorium; influenza and pulmonary tuberculosis. | 1954 | 13188754 | |
[new subtype of influenza virus b]. | 1954 | 13196632 | |
[comparative evaluation of methods of laboratory diagnosis of influenza b]. | 1953 | 13205669 | |
[data on virusologic and serologic study of influenza b]. | 1953 | 13205671 | |
recombination with two influenza b strains in the de-embryonated egg. | 1954 | 13208487 | |
influenza b in boston, 1952; isolations of virus and serologic studies in patients, including a study of antigenic differences among influenza b viruses isolated in boston from 1945 to 1952. | 1955 | 13228410 | |
the influence of cortisone on experimental viral infection. i. prolongation of survival time and suppression of inflammation in chick embryos infected with influenza b virus. | 1955 | 13233520 | |
isolation and cytopathogenic effect of influenza b viruses in monkey kidney cultures. | 1955 | 13254857 | |
reproduction of influenza viruses; quantitative investigations with particle enumeration procedures on the dynamics of influenza a and b virus reproduction. | influenza a and b virus reproduction in the allantoic membrane of the intact chicken embryo was studied quantitatively with particle enumeration procedures. virus particles were enumerated on the basis of two independent properties; capacity to infect and to cause hemagglutination. the infective property of influenza b virus (lee) was even more unstable than that of influenza a virus (pr8). inactivation occurred at a constant logarithmic rate which was independent of the concentration of particl ... | 1955 | 13263486 |
inhibition of mumps and influenza b virus multiplication by synthetic poly-d-lysine. | 1956 | 13297788 | |
[characteristics of biological properties of strains of influenza virus b isolated in leningrad during the recent years]. | 1955 | 13300912 | |
[two cases of polyradiculoneuritis caused by influenza virus b]. | 1956 | 13309034 | |
[clinical, serological and epidemiological experiences during the influenza b epidemics in 1954-55]. | 1956 | 13321811 | |
selective chemical inhibition of influenza b virus multiplication. | 1956 | 13345773 | |
high inhibitory activity of certain halogenated ribofuranosylbenzimidazoles on influenza b virus multiplication. | 1956 | 13345774 | |
certain benzimidazoles, benzenes, and ribofuranosylpurines as inhibitors of influenza b virus multiplication. | 1956 | 13345775 | |
[antigenic properties of influenza virus b isolated in 1950]. | 1956 | 13352962 | |
an analysis of the process of adaptation of influenza virus b of recent human origin to the mouse lung. | 1956 | 13357714 | |
an evaluation of an adjuvant influenza virus vaccine tested against influenza b in 1954-1955. | 1956 | 13372524 | |
[virological and biological characteristics of influenza virus b isolated during 1955]. | 1956 | 13392712 | |
[severe bronchopneumopathy caused by apc virus with probable pneumococcal superinfection developing after influenza b virus infection]. | 1956 | 13396602 | |
[epidemiological observations in east hesse during influenza b epidemic in 1955]. | 1957 | 13423631 | |
enzymatic variants of influenza virus. i. isolation and characterization of slowly reacting enzymatic variants of influenza b virus. | slowly reacting enzymatic variants of the lee strain of influenza b virus were isolated by the serial application of a technique which concentrated the fraction of the virus population obtained by slow elution followed by passage of this fraction at high dilution in chicken embryos. the variants were stable upon serial passage in chicken embryos and did not differ significantly from the parent virus in any of the characteristics tested other than those relating to the virus enzyme. enzymatically ... | 1957 | 13439115 |
studies on the enzymatic properties of influenza viruses. i. the action of influenza b virus and rde on the hemagglutinin inhibitor of human meconium. | 1957 | 13443208 | |
[homologous interference by heat-inactivated influenza-b-virus absorbed on erythrocytes]. | 1957 | 13447900 | |
[cleavage of n-acetyl-neuraminic acid from serum by influenza virus b (lee) and a-toxin of clostridium welchii]. | 1957 | 13474661 | |
the influence of cortisone on experimental viral infection. iil effects on certain dynamics of influenza virus increase. | the administration of cortisone to chicken embryos infected with influenza b virus results in (a) an initial inhibition of viral synthesis and (b) an eventual increase in the final yield of virus attained. increased yields of virus are attained regardless of the number of viral particles in the infecting inoculum or the proportion of particles which are infective. changes in the distribution ratios of allantoic fluid and intramembrane virus are effected by cortisone only as the secondary result ... | 1957 | 13481248 |
the influence of cortisone on experimental viral infection. iv. negation of interference as the mechanism by which cortisone induces increased virus yields. | the interference with viral synthesis which is induced by large quantities of non-infective influenza b virus is inhibited or negated with small quantities of cortisone and other c-21 steroids. the specificity of this effect is attested by the inactivity of 11-alpha hydroxy epimers of highly active compounds. maximal activity in negation of interference is associated with the presence of oxygen at the c-11 position of the steroid molecule. in view of the demonstration that negation of interferen ... | 1957 | 13481249 |
[antibody titers against influenza virus type b and against the far east strain of influenza virus in slovak inhabitants towards the end of 1957]. | 1958 | 13585398 | |
enzymatic variants of influenza virus. ii. effect of environmental factors on enzymatic characteristics of a variant of influenza b virus. | the rate of elution of the variant virus from chicken rbc is progressively decreased as the temperature of incubation is increased above 25 degrees c. the activity of the parent virus, on the other hand, is increased as the temperature is increased up to 40 degrees c. the major cause of the decreased activity of the variant at temperatures above 2s degrees c. is an inhibition of the variant enzyme rather than its inactivation. the activity of the variant enzyme is stimulated in the presence of s ... | 1958 | 13587849 |
protective effect of seaweed extracts for chicken embryos infected with influenza b or mumps virus. | 1958 | 13614432 | |
development of resistance of influenza b virus to polysaccharides. | algal polysaccharide obtained from carrageenin protects 80 to 100 percent of chicken embryos against fatal infections with the lee strain of influenza virus. this report describes the rapid emergence of a stable variant of this virus which is resistant to the protective action of this polysaccharide. | 1958 | 13615309 |
antibodies to asian influenza and influenza b: edinburgh, 1958. | 1959 | 13629023 | |
some new or little-known respiratory viruses. | the characters and relationships of a number of viruses of potential importance in human respiratory diseases are reviewed. among the myxoviruses discussed are viruses related to influenza a (swine and horse influenza, british and czechoslovak duck influenza, fowl plague), influenza b and c, mumps and newcastle disease, and the para-influenzas. the echo viruses, 2060 and jh viruses, chimpanzee coryza agent and the common cold are also considered. in the final section of the paper the attempted t ... | 1959 | 13651924 |
[a new photometric technic for titration of the hemagglutination power of mixed viruses. i. influenza virus type b]. | 1959 | 13663474 | |
[basic properties of hemagglutination by influenza virus b]. | 1959 | 13663475 | |
phylogenetic analysis reveals a low rate of homologous recombination in negative-sense rna viruses. | recombination is increasingly seen as an important means of shaping genetic diversity in rna viruses. however, observed recombination frequencies vary widely among those viruses studied to date, with only sporadic occurrences reported in rna viruses with negative-sense genomes. to determine the extent of homologous recombination in negative-sense rna viruses, phylogenetic analyses of 79 gene sequence alignments from 35 negative-sense rna viruses (a total of 2154 sequences) were carried out. powe ... | 2003 | 13679603 |
[clinical aspects and therapy of influenza b during the period of the winter outbreak]. | 1960 | 13682268 | |
[evaluation of the preventive action of 1,1-(3-oxapentamethylene)-biguanide in an outbreak of influenza b]. | 1960 | 13690293 | |
an outbreak of influenza b in panama. | 1961 | 13696218 | |
spectrum and characteristics of the virus inhibitory action of 2-(alpha-hydroxybenzyl)-benzimidazole. | 2-(alpha-hydroxybenzyl)-benzimidazole (hbb) inhibited the cytopathic effects of the following enteroviruses: polio 1 to 3; coxsackie a9; coxsackie b 1 to 6; and echo virus types 1 to 9, 11 to 21, and 24 to 27. the following enteroviruses were not inhibited: coxsackie a types 7, 11, 13, 16, and 18; and echo types 22, 23, and 28. other hbb-insusceptible viruses were: arbor b and c, reo 1 to 3; adeno 2 to 4; influenza b; para-influenza 2 and 3; mumps; herpes simplex, and vaccinia. hbb had no inacti ... | 1961 | 13725919 |
relationship between structure of benzimidazole derivatives and selective virus inhibitory activity. inhibition of poliovirus multiplication and cytopathic effects by 2-(alpha-hydroxybenzyl)-benzimidazole, and its 5-chloroderivative. | the virus inhibitory activity and selectivity of certain benzimidazole, benzotriazole, and naphthimidazole derivatives were determined with influenza b and polio type 2 viruses. among the sixty-five compounds examined, several were highly active inhibitors of influenza b virus multiplication in the chorioallantoic membrane in vitro. the following compounds, listed in order of increasing inhibitory activity, were more than 100 times as active as benzimidazole: 5-(4'-toluenesulfonamido)-benzimidaz ... | 1961 | 13775109 |
[epidemic influenza b virus outbreak rampant this summer in tunisia]. | 1961 | 13877830 | |
[increased sensitivity of 1-layer tissue cultures to influenza b and se-polyoma viruses in a modified method of infection of cell suspensions]. | 2016 | 13884917 | |
serial propagation of influenza b (lee) virus in a transmissible line of canine kidney cells. | the serial propagation of influenza b (lee) virus has been demonstrated in a transmissible line of canine kidney cells, as evidenced by the presence of cytopathic effects and hemagglutinins in each of six consecutive tissue-culture passages, and by egg infectivity titers of 10-4.3 and 10-4.1 per 0.1 ml in 3rd and 5th tissue culture fluids, respectively. | 1962 | 13901412 |
[influenza b viruses]. | 2016 | 13915025 |