Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| campylobacter-host cell interactions. | the enteric pathogens campylobacter jejuni and campylobacter coli are a major cause of infectious diarrhoea. their ability to adhere to human epithelial cells is ubiquitous and their propensity to invade cells is also well documented and requires motility and de novo protein synthesis, as well as several host factors. the molecular basis of the interaction between campylobacters and host cells is only beginning to be elucidate. the characteristics of this interaction promise to be interesting an ... | 1997 | 9080607 |
| outbreak of campylobacter enteritis in a residential school associated with bird pecked bottle tops. | an outbreak of gastroenteritis caused by campylobacter infection was identified in may 1995 in a residential school in gloucestershire for children with special needs. eight primary and four secondary cases were identified, mostly confined to one house in the school; faecal specimens from three cases grew campylobacter jejuni. a retrospective cohort study showed that drinking pasteurised milk from bottles with damaged tops was associated with illness in primary cases (p = 0.01). bird pecking of ... | 1997 | 9080727 |
| [current parameters of the epidemiological process in campylobacteriosis]. | data on some parameters of the epidemic process of campylobacteriosis in the ukraine are presented. campylobacteriosis patients were found to constitute 1.9 +/- 0.095% of all examined patients with acute enteric infections (aei). no statistically significant difference in the proportion of campylobacteriosis among child and adult aei patients was established. the proportion of sick persons at the period of the spring-summer rise in morbidity was 71.5%. a definite relationship between the epizoot ... | 1996 | 9082723 |
| cranial polyneuropathy with elevated serum antiganglioside antibody. | we report a 6-year-old girl with cranial polyneuropathy with elevated serum levels of antiganglioside antibodies. she manifested herpetic vesicles around the right upper eyelid and mouth without antecedent infection. she developed facial asymmetry and double vision 5 days after the first appearance of the vesicles. neurological examination on admission disclosed palsies of the bilateral sixth and twelfth cranial nerves and right third and seventh cranial nerves, but limb muscle weakness, ataxia, ... | 1997 | 9090691 |
| [guillain-barre syndrome and antibodies to ganglioside gm1. case report]. | a sudden onset of the syndrome guillain-barré in 48-year-old woman presenting as an acute motor neuropathy was associated with antibodies against ganglioside gm1 detected by elisa. the neurological examination revealed flaccid quadriplegia without affection of the sensory system, and the additional investigation showed mild increase of the csf protein content, demyelination of the peripheral motor nerves and significantly increased titer of the serum and csf anti-gm1 antibodies. several coprucul ... | 1996 | 9102850 |
| [guillain-barré syndrome and fisher syndrome]. | guillain-barré syndrome is an acute inflammatory polyneuropathy that usually follows infections. fisher syndrome is a variant of guillain-barré syndrome, the triads of which are ophthalmoplegia, ataxia and areflexia. although the agents for the preceding infections cannot be determined in many cases, those viruses such as cytomegalovirus, epstein-barr virus, and hiv as well as mycoplasma and bacteria including campylobacter jejuni have been reported. the pathogenetic mechanisms may be immune-med ... | 1997 | 9103898 |
| acute motor axonal neuropathy with high titer igg and iga anti-gd1a antibodies following campylobacter enteritis. | we describe the first two european cases of acute axonal motor neuropathy with both igg and iga anti-gd1a antibodies following campylobacter enteritis. both patients acutely developed severe weakness without sensory involvement, had antibodies to campylobacter jejuni and polyclonal igg and iga titers > or = 12,800 to gd1a at onset, which decreased during follow-up. serial electrophysiologic studies showed: 1, normal or only slightly slowed motor conductions; 2, evidence of a progressive loss of ... | 1997 | 9106127 |
| a diffusible cytotoxin of haemophilus ducreyi. | little is known about the virulence mechanisms employed by haemophilus ducreyi in the production of genital ulcers. this gram-negative bacterium previously has been shown to produce a soluble cytotoxic activity that kills hela and hep-2 cells. we have now identified a cluster of three h. ducreyi genes that encode this cytotoxic activity. the predicted proteins encoded by these genes are most similar to the products of the escherichia coli cdtabc genes that comprise the cytolethal distending toxi ... | 1997 | 9108104 |
| history of macrolide use in pediatrics. | erythromycin, the prototypical macrolide, has been widely used since the 1950s in the management of pediatric infections. erythromycin is the drug of choice for infants and children with legionnaire's disease, pertussis, diphtheria, lower respiratory tract infections caused by mycoplasma pneumoniae, chlamydia pneumoniae and chlamydia trachomatis and enteritis caused by campylobacter jejuni. it is also indicated for treatment of syphilis; for streptococcal, staphylococcal and pneumococcal infecti ... | 1997 | 9109154 |
| [the antibiotic susceptibility of campylobacter strains isolated in moldova. the possibilities for estimation and the results]. | susceptibility to antibiotics of 39 campylobacter jejuni/coli strains was appreciated using the modified disc method (sowing by loop). eighteen strains were examined in duplicate using the conventional disc susceptibility method (sowing by inundation). based on the diameters (mm) of growth inhibition zones and on the respective critical concentrations (mcg/ml) the mics were also appreciated. all the strains were resistant to rifampicin, polymyxin m sulphate, ketokonazole, cephalotin, cephazolin; ... | 1996 | 9116399 |
| the campylobacter jejuni porin trimers pack into different lattice types when reconstituted in the presence of lipid. | purified major outer membrane protein of campylobacter jejuni exhibited different classes of molecules by sds/page and immunoblotting. a high-molecular-mass product (120-140 kda) was observed under mild conditions of solubilization, a folded monomeric form of 35 kda was seen when treated at high sds concentrations and finally, a single band around 45 kda occurred when the sample was heated to 96 degrees c [bolla, j. m., loret, e., zalewski. m. & pages, j. m. (1995) j. bacteriol. 177, 4266-4271]. ... | 1997 | 9119026 |
| close association of guillain-barré syndrome with antibodies to minor monosialogangliosides gm1b and gm1 alpha. | cumulative evidence supports the theory that anti-ganglioside antibodies function in the development of guillain-barré syndrome (gbs). some patients have developed gbs after the administration of monosialoganglioside extracted from bovine brain. to clarify the pathogenesis of gbs associated with and without administration of the monosialoganglioside fraction, we investigated serum antibodies to the minor monosialogangliosides gm1b and gm1 alpha in patients with gbs and in control patients. gm1b ... | 1997 | 9119976 |
| a mixed foodborne outbreak with salmonella heidelberg and campylobacter jejuni in a nursing home. | to investigate a mixed salmonella heidelberg and campylobacter jejuni foodborne outbreak in a nursing home. | 1997 | 9120239 |
| identification of the tetracycline resistance gene, tet(o), in streptococcus pneumoniae. | five isolates of streptococcus pneumoniae resistant to tetracycline but lacking tet(m) were studied. the tetracycline resistance gene, tet(o), was detected for the first time in the pneumococcus. the gene was amplified and sequenced and found to share 99% nucleotide sequence identity and 99, 99, and 98% deduced amino acid sequence identity with the tet(o) resistance genes of streptococcus mutans, campylobacter coli, and campylobacter jejuni, respectively. | 1996 | 9124862 |
| antibiotic resistance of campylobacter jejuni with reference to plasmid profiles of clinical and chicken isolates. | a total of 47 clinical isolates and 52 poultry isolates of campylobacter jejuni were characterized by their resistance to 16 antimicrobial agents and by plasmid profiles on agarose gel electrophoresis. almost all isolates were susceptible to erythromycin, chloramphenicol, gentamycin and nitrofuratoin. plasmids were detected in 19% of c. jejuni strains isolated from feces of children patients and in 36% of strains isolated from chicken. the presence of plasmid dna was not found to be correlated w ... | 1996 | 9127480 |
| complete nucleotide sequence of the campylobacter jejuni 72dz asd gene. | campylobacter jejuni asd gene was sequenced. the gc content of the gene coding region is 32.7%. the codon usage is typical for a gene in a genome with low gc content. the structure of the gene regulatory sequences resembles that one used for escherichia coli gene transcription and translation. the amino acid sequence of the asd protein exhibits significant homology to asd gene products from other microorganisms. | 1996 | 9127485 |
| detection of the coccoid form of campylobacter jejuni with the use of polymerase chain reaction. | the incubation of campylobacter jejuni in aerobic conditions results in transformation of spiral cells into coccoid form. it is shown in presented paper that the assay of coccoid of c. jejuni with pcr is limited. its detectability decreases with the increase of time and temperature of cell storage. | 1996 | 9127486 |
| genotype analysis of human blood isolates of campylobacter jejuni in england and wales. | genomic profiles were obtained for 76 strains of campylobacter jejuni isolated from bacteraemic patients in england and wales over the period 1981-94. genotyping was performed by restriction fragment length polymorphism (rflp) analysis using a random cloned dna probe, and by ribotyping with a pcr-generated c. jejuni 16s ribosomal dna probe. phenotypic characterization was achieved by heat-stable (hs) and heat-labile (hl) serogrouping, and preston phagetyping and biotyping. the blood isolates wer ... | 1997 | 9129583 |
| the serotype distribution of campylobacter jejuni and c. coli isolated from patients with diarrhoea and controls at tikur anbassa hospital, addis ababa, ethiopia. | sixty-eight isolates of campylobacter jejuni and c. coli isolated from patients with diarrhoea (n = 630) and controls (n = 220) at tikur anbassa hospital, addis ababa, ethiopia were serotyped on the basis of the heat-labile (hl) and the heat-stable (hs) antigens, by using 16 and 34 antisera, respectively, for the two methods. with the antisera against heat labile antigens, 89.3% of the c. jejuni and 75% of the c. coli were typable. the hl serotypes 1, 2, 3, 4, 5, 6 and 7 were the most common amo ... | 1997 | 9129584 |
| cloning of an outer membrane protein gene from campylobacter jejuni. | an antigen in the outer membrane protein (omp) fraction of campylobacter jejuni was identified and characterized. western blot analysis demonstrated antigenic differences in this protein between two congenic c. jejuni strains. strain a74/c, which colonizes chickens, expressed the antigen at 34 kda, while strain a74/o, which poorly colonizes chickens, expressed the antigen at 32 and 34 kda. a genomic library was constructed in lambdagt11 with dna from a74/o and screened with antibody raised again ... | 1997 | 9142743 |
| in vitro permeation of human chorioamniotic membranes by campylobacter jejuni. | in vitro penetration of human chorioamniotic membranes by campylobacter jejuni was investigated by an organ culture model. membrane permeation was detected by an immunoperoxidase technique and viable bacterial counts of membrane homogenates. human clinical isolates of c. jejuni inoculated on the maternal side of the membranes penetrated to the fetal side suggesting that chorioamniotic membranes constituted a weak barrier against campylobacter infection. chicken fecal isolates did not penetrate c ... | 1997 | 9144913 |
| [a case of guillain-barré syndrome after the travel in southeast asia--isolation of campylobacter jejuni pen 5 serotype]. | a 57-year-old man, while on travel in malaysia, suffered from diarrhea after he ate fruits. he developed limbs weakness without sensory disturbance after his return to japan. serum from the patient had high igg anti-gm1 antibody titer. campylobacter jejuni was isolated from his stool. the serotype belonged to pen 5. the patient received double-filtration plasmapheresis 7 times during from days 6 to 17. muscle strength began to recover gradually on day 10, and returned to normal 5 months after th ... | 1997 | 9146072 |
| campylobacter spp. and salmonella spp. in black-headed gulls (larus ridibundus). | cloacal examination of 41 juvenile black-headed gulls (larus ridibundus) by cultivation demonstrated campylobacter jejuni in 26 (63%) and salmonella typhimurium in 21 (51%) of them. all the bird samples were collected in a breeding colony near the town hodonin, south moravia, czech republic in 1996. twenty six campylobacter isolates were tested for antibiotic and drug sensitivity: all were resistant to at least three agents (penicillin, tetracyclin and sulfomethoxazol-trimethoprim) while all wer ... | 1997 | 9151001 |
| [analysis of the swimming pattern and the velocity of bacteria using video tracking method]. | the swimming patterns and the velocities of several flagellated bacteria were measured by a computer assisted video tracking method. the moving path of the individual bacterium revealed that the bacterium frequently changed its swimming direction and velocity. the velocity among bacterial strains varies widely. in low viscous environment. campylobacter jejuni has characteristic swimming pattern with frequent changes in their swimming direction. as the viscosity increase, c. jejuni increases its ... | 1997 | 9154715 |
| immunological detection of lipopolysaccharide antigens of thermophilic campylobacters captured on polymyxin-coated polyester cloth. | cholate-extracted lipopolysaccharide (lps) antigens from thermophilic campylobacters were captured on polymyxin-coated polyester cloth. the captured antigens were detected by sequential reactions with rabbit anti-campylobacter antibody, anti-rabbit igg peroxidase conjugate and chromogenic peroxidase substrate. a polyclonal rabbit antibody elicited against a single campylobacter-jejuni strain detected the reference strains of the twenty most frequently isolated thermophilic campylobacters in the ... | 1996 | 9157052 |
| flagellin gene profiling of campylobacter jejuni heat-stable serotype 1 and 4 complex. | flagellin gene (flaa) sequence polymorphisms were used to discriminate amongst 167 strains of campylobacter jejuni serotype hs1 and the hs4 complex. direct pcr of cell suspensions provided a rapid method for analysing dnase-negative strains, whereas purified dna was necessary for the dnase-positive strains. nine different pcr-rflp patterns (genotypes) were identified by analysis with hinfl and 12 with ddel, giving a total of 19 combined flaa profile types. the most common combined fla types were ... | 1996 | 9157491 |
| [campylobacter jejuni septicemia with cutaneous sites in a patient with human immunodeficiency virus infection]. | 1997 | 9161581 | |
| primary structure analysis and adhesion studies on the major outer membrane protein of campylobacter jejuni. | the major outer membrane protein of campylobacter jejuni (momp, 43 kda), supposed to be one of the structures responsible for adhesion to int 407 cells, was isolated from the crude outer membrane preparation by treatment with n-octyl-beta-d-glucopyranoside followed by preparative sds-polyacrylamide gel electrophoresis. by cleavage of the isolated protein with cyanogen bromide and proteolytic enzymes, peptides were generated, separated by reverse phase high pressure liquid chromatography, and seq ... | 1997 | 9163918 |
| resuscitation of 'non-culturable' cells from aged cultures of campylobacter jejuni. | when stationary phase batch cultures of campylobacter jejuni were stored in sealed flasks under static conditions, viable numbers declined from 2 x 10(9) c.f.u. ml-1 to around 10(3)-10(6) c.f.u. ml-1 within 4-6 weeks. when the aged cultures were sparged with a microaerobic gas mixture, there was a rapid increase in viable numbers accompanied by a change from predominantly coccoid to vibrioid morphology. the most probable number (mpn) technique was used to distinguish resuscitation of injured or ... | 1997 | 9168608 |
| changes with growth rate in the membrane lipid composition of and amino acid utilization by continuous cultures of campylobacter jejuni. | methods and media (defined and complex) are described which permit studies designed to determine the influence of single environmental factors on the survival and virulence of campylobacter jejuni. the effect of growth rate on selected physiological traits (amino acid utilization, membrane lipid composition, motility, cell morphology) was studied in continuous culture. in both media, growth was at the expense of amino acid (serine, aspartate, glutamate and proline) catabolism. slow growth in the ... | 1997 | 9172406 |
| fulminant guillain-barré syndrome with universal inexcitability of peripheral nerves: a clinicopathological study. | the pathological basis of nerve inexcitability in guillain-barré syndrome has not been established with certainty. we report the clinicopathological findings in a 67-year-old patient with fulminant guillain-barré syndrome who died 18 days after onset. three serial electrophysiological studies revealed nerve inexcitability. antibodies to campylobacter jejuni were present but there was no antiganglioside reactivity. spinal root sections revealed extensive and almost pure macrophage-associated demy ... | 1997 | 9179157 |
| campylobacter jejuni gastroenteritis in turkish children. | four hundred children between the ages of 1 month and 14 years with the complaint of diarrhea were studied to assess campylobacter jejuni isolation rates in childhood acute gastroenteritis in turkey and to clarify clinical presentations of c. jejuni enteritis. c. jejuni was found to be the second most common isolate with a rate of 8.3%, the first being shigella strains. the highest isolation rate was in the 6 to 14-year age range at 12%. the most frequent symptoms in patients with c. jejuni ente ... | 1997 | 9181383 |
| oral administration of antibodies as prophylaxis and therapy in campylobacter jejuni-infected chickens. | passive immunity against gastrointestinal infections has recently been successfully applied as prophylaxis and therapy in patients in a variety of virally and bacterially induced infections. campylobacter jejuni is frequently associated with acute diarrhoea in humans, and several species of animals have been shown to transmit the disease, although birds have been implicated as the main source of infection. we used bovine and chicken immunoglobulin preparations from the milk and eggs, respectivel ... | 1997 | 9182891 |
| cloning, sequencing, and expression of a campylobacter jejuni periplasmic binding protein (p29) involved in histidine transport. | 1997 | 9192026 | |
| serendipitous detection of persistent campylobacter jejuni subspecies jejuni bacteremia in a patient undergoing bone marrow transplantation. | 1997 | 9195103 | |
| nested polymerase chain reaction strategy simultaneously targeting dna sequences of multiple bacterial species in inflammatory joint diseases. i. screening of synovial fluid samples of patients with spondyloarthropathies and other arthritides. | bacteria play a crucial pathogenetic role in lyme arthritis (la), reactive arthritis (rea), other forms of spondyloarthropathy (spa), and possibly in undifferentiated oligoarthritis (uoligo). polymerase chain reaction (pcr) technology has been applied to detect bacterial dna of individual microbes in synovial fluid (sf) of patients with arthritides. we screened for dna sequences of 8 bacterial species simultaneously in sf of patients with inflammatory joint disease. | 1997 | 9195515 |
| nested polymerase chain reaction strategy simultaneously targeting dna sequences of multiple bacterial species in inflammatory joint diseases. ii. examination of sacroiliac and knee joint biopsies of patients with spondyloarthropathies and other arthritides. | bacteria play a crucial pathogenetic role in reactive arthritis (rea) and other forms of spondyloarthropathy (spa) and in lyme arthritis. although there is evidence of local persistence of bacterial antigens no definitive method revealing microbes in peripheral joints has been established. we detected dna of individual bacteria in synovial material by pcr. applying molecular technology we screened simultaneously for 8 bacterial genomes in arthritis and sacroiliitis. | 1997 | 9195516 |
| [intervention of campylobacter jejuni subsp. jejuni flagella in the adhesion to cellular cultures: bacteriological and immunological evidence]. | the participation of the flagella of a virulent strain (o52) of campylobacter jejuni subsp. jejuni in the adhesion to hep-2 cells and their inhibition by means of homologous polyclonal antibodies, monoclonal anti-flagella antibodies and colostral natural antibodies (iga) was studied. an aflagellated strain (t1) was used as negative control. adhesion was observed in higher rates with o52 strain (72%) than with t1 strain (27.5%). polyclonal, monoclonal and colostral antibodies inhibited o52 strain ... | 1996 | 9197015 |
| restriction endonuclease analysis, dna relatedness and phenotypic characterization of campylobacter jejuni and camp. coli isolates involved in food-borne disease. | seven cases of campylobacter infection, each of them involving two isolates, were analysed. study of their biochemical profiles and susceptibility patterns allowed the identification of camp. jejuni and camp. coli isolates and the effective typing of camp. jejuni strains into biotypes. genotyping was carried out by comparing chromosomal dna restriction patterns obtained by cleavage with bg/ii and ecorv and by southern hybridization experiments. these studies revealed clonal homogeneity between b ... | 1997 | 9202438 |
| adherence, invasion and cytotoxin assay of campylobacter jejuni in hela and hep-2 cells. | campylobacter jejuni is an important human enteropathogen worldwide. chickens are the major reservoir and source of campylobacter infection. ten clinical isolates from human and five chicken strains were tested for the adherence, invasion and cytotoxin assay in hela and hep-2 cells. all human strains adhered to both the hela (10(3) to 3 x 10(4) bacteria/ml of cell lysate) and hep-2 cells (2 x 10(3) to 4 x 10(4) bacteria/ml of lysate). all chicken strains also adhered to the hep-2 cells (10(2) to ... | 1996 | 9203788 |
| disc susceptibility testing for thermomphilic campylobacters. | the minimum inhibitory concentrations (mics) and zone diameters around nccls strength discs of 100 clinical isolates of thermophilic campylobacter species, including 79 strains of campylobacter jejuni subsp. jejuni, 19 of c. coli and two of c. lari, plus three type strains of these species, were determined for erythromycin, clindamycin, nalidixic acid, norfloxacin, ciprofloxacin, ampicillin, piperacillin, cephalothin, ceftriaxone, chloramphenicol, gentamicin and tetracycline. using error-rate bo ... | 1997 | 9213344 |
| fatal campylobacter jejuni infection in a patient splenectomised for thalassaemia. | a 35 year old man with a fatal campylobacter jejuni infection is described. he had hbe/beta zero thalassaemia and had undergone splenectomy nine months previously for hypersplenism; he also had chronic hepatitis c infection. he presented with high grade fever but no gastrointestinal symptoms and rapidly progressed to septicaemic shock and hepatic encephalopathy despite treatment with penicillin, gentamicin, and, later, chloramphenicol and ceftazidime. only one case of campylobacter jejuni septic ... | 1997 | 9215130 |
| stimulation of peripheral blood lymphocytes with campylobacter jejuni generates a gammadelta t cell response in patients with guillain-barrésyndrome. | in three patients whose guillain-barré syndrome (gbs) was preceded by gastrointestinal infection due to campylobacter jejuni, gammadelta t cells were generated from peripheral blood in response to in vitro stimulation with c. jejuni. in one of the patients, where a diagnostic sural nerve biopsy was performed, gammadelta t cells were also isolated following culture of the nerve tissue. studies with healthy volunteers and c. jejuni gastroenteritis patients also showed preferential enrichment for g ... | 1997 | 9218834 |
| identification and molecular cloning of a gene encoding a fibronectin-binding protein (cadf) from campylobacter jejuni. | campylobacter jejuni, a gram-negative bacterium, is a common cause of gastrointestinal disease. by analogy with other enteric pathogens such as salmonella and shigella, the ability of c. jejuni to bind to host cells is thought to be essential in the pathogenesis of enteritis. scanning electron microscopy of infected int407 cells suggested that c. jejuni bound to a component of the extracellular matrix. binding assays using immobilized extracellular matrix proteins and soluble fibronectin showed ... | 1997 | 9220003 |
| a new cytolethal distending toxin (cdt) from escherichia coli producing cnf2 blocks hela cell division in g2/m phase. | escherichia coli strain 1404, isolated from a septicaemic calf, carries a transferable plasmid called pvir which codes for the cytotoxic necrotizing factor type 2 (cnf2). a 4h interaction between strain 1404 and hela cells induced the formation of giant mononucleated cells blocked in g2/m phase. mating experiments between strain 1404 and a non-pathogenic recipient strain demonstrated that the factor(s) encoded by pvir mediated the cell-cycle arrest. a 3.3 kb dna fragment isolated from a dna bank ... | 1997 | 9220015 |
| comparison of disc diffusion and agar dilution methods for antibiotic susceptibility testing of campylobacter jejuni subsp. jejuni and campylobacter coli. | the correlation between disc diffusion and agar dilution susceptibility testing of five antibiotics was studied against 145 campylobacter strains: 99 campylobacter jejuni subsp. jejuni and 46 campylobacter coli. the percentages of true results and 95% ci for disc diffusion for resistant strains were 100% (93.2-100%) for tetracycline (53 strains tested), 100% (77.2-100%) for ciprofloxacin (13 strains tested), 86.7% (62.1-96.3%) for nalidixic acid (15 strains tested), 100% (56.6-100%) for erythrom ... | 1997 | 9222038 |
| association of campylobacter jejuni serotype with antiganglioside antibody in guillain-barré syndrome and fisher's syndrome. | using penner's method and lior's scheme, we serotyped 31 isolates from patients with guillain-barré syndrome, 7 isolates from those with fisher's syndrome, and isolates from patients with sporadic enteritis. pen 19 of campylobacter jejuni was isolated more frequently from the guillain-barré syndrome patients (16/31 isolates, 52%) than from the sporadic enteritis patients (5%). lio 7 of c. jejuni also was isolated more frequently from the gillain-barré syndrome patients (14/31 isolates, 45%) than ... | 1997 | 9225682 |
| toxin production by campylobacter spp. | of all the virulence factors that were proposed for campylobacter jejuni and related species to cause disease in humans, the discovery of toxin production was the most promising but led to a rather confusing and even disappointing stream of data. the discussion of whether proteinaceous exotoxins are relevant in disease remains open. one important reason for this lack of consensus is the anecdotal nature of the literature reports. to provide a basis for an unbiased opinion, this review compiles a ... | 1997 | 9227862 |
| molecular discrimination between campylobacter jejuni, campylobacter coli, campylobacter lari and campylobacter upsaliensis by polymerase chain reaction based on a novel putative gtpase gene. | polymerase chain reaction (pcr) mediated dna fingerprinting has resulted in the identification of a novel campylobacter jejuni gene, encoding a gtpase protein. the gene, consisting of 383 amino acids contained semi-conserved gtp-binding sites (designated g-1 to g-4), that are characteristic for members of the gtpase protein superfamily. remarkably, this gene from c. jejuni appears to encode a member of a novel family of gtp-binding proteins, containing two separate putative gtp-binding domains, ... | 1997 | 9232616 |
| differentiation of campylobacter jejuni and campylobacter coli by polymerase chain reaction. | a multiplex pcr assay was developed using two primer sets for the identification and differentiation of campylobacter coli and campylobacter jejuni. primer set i amplifies a 460-bp fragment present in c. coli and c. jejuni. set ii amplifies a 160-bp target unique to c. jejuni. when the assay was performed on reference strains, amplification of c. coli yielded only the 460-bp fragment. amplification of c. jejuni generated both the 160- and 460-bp fragments. campylobacter field strains (n = 85) is ... | 1997 | 9232618 |
| evaluation of the nasba nucleic acid amplification system for assessment of the viability of campylobacter jejuni. | although nasba uses rna as a target molecule for amplification, the nucleic acid amplification system cannot be used for differentiating viable and non-viable c. jejuni. it was shown that 16s rrna, or the defined sequence within the 16s rrna enclosed by the primer set applied, is fairly stable and resistant to heating at 100 degrees c. false-positive results can occur in case of direct nasba detection of c. jejuni in foods. these false positive results due to amplification of rna from dead cells ... | 1997 | 9237117 |
| characterization of monoclonal antibodies for the rapid detection of foodborne campylobacters. | the specificity of 97 monoclonal antibodies (mabs) to the campylobacter jejuni lior serogroup 6 reference strain was assessed using an indirect enzyme linked immunosorbent assay (elisa). four mabs, m316, m337, m357 and m637, reacted with whole cells of the c. jejuni, c. coli and c. lari reference strains of the 20 most common lior serogroups and 25 recent c. jejuni and c. coli isolates, and did not react with most of the 42 other campylobacter and non-campylobacter spp. tested. immunoblot analys ... | 1997 | 9237126 |
| preferential interaction of the his pause rna hairpin with rna polymerase beta subunit residues 904-950 correlates with strong transcriptional pausing. | rna secondary structures (hairpins) that form as the nascent rna emerges from rna polymerase are important components of many signals that regulate transcription, including some pause sites, all rho-independent terminators, and some antiterminators. at the his leader pause site, a 5-bp-stem, 8-nt-loop pause rna hairpin forms 11 nt from the rna 3' end and stabilizes a transcription complex conformation slow to react with ntp substrate. this stabilization appears to depend at least in part on an i ... | 1997 | 9237994 |
| [participation of campylobacter jejuni flagellar epitopes in cellular adhesion]. | using a flagellated (052) and an aflagellated (t-1) strains we studied the participation of flagellar epitopes of c. jejuni in the adhesion to hep-2 cells in vitro. strain 052 was significantly more adherent than strain t-1. when adhesion assays were carried out with antiflagella monoclonal antibodies, strain 052 showed inhibition of their adhesive capacity that varied between 64.3 and 92.9%. with an elisa test it was demonstrated that those monoclonal antibodies were specific and directed exclu ... | 1996 | 9239884 |
| campylobacter 0:41 isolation in guillain-barré syndrome. | over a period of 15 months, 17 children were admitted to the red cross war memorial children's hospital (rcwmch) in cape town with guillain-barré syndrome. stool specimens were collected from 14 children and campylobacter was isolated from nine. six of the nine isolates of campylobacter jejuni were further identified as c jejuni biotype 2, serotype 0:41. this biotype 2, serotype 0:41 has been identified in only 12 of the 7119 campylobacter isolates at the rcwmch over a 19 year period. eight of t ... | 1997 | 9245852 |
| overproduction of campylobacter ferritin in escherichia coli and induction of paracrystalline inclusion by ferrous compound. | the ferritin gene (cft) of campylobacter jejuni was overexpressed in cells of escherichia coli using a t7 rna polymerase expression system. many round particles which were the same size as the ferritin particles purified from c. jejuni were observed in the lysate of the cft-overexpressed e. coli cells. since most of them were devoid of a central electron dense core consisting of ferric irons, the campylobacter ferritins over-produced in e. coli seemed to be apoferritin. when large amounts of fer ... | 1997 | 9251057 |
| invasive and enterotoxic properties in campylobacter jejuni and campylobacter coli strains isolated from humans and animals. | invasive properties of 15 strains of thermotolerant campylobacter (12 c. jejuni and 3 c. coli) were studied using hela cells cultures. in four of them (3 c. jejuni and 1 c. coli), randomly selected, intestinal perfusion experiments were conducted in order to asses enterotoxigenicity. all strains were able to invade hela cells. the number of invaded hela cells ranged from 3 to 46%. in addition to their invasive properties, the 4 strains used in perfusion experiments were able to induce either a n ... | 1995 | 9251750 |
| helicobacter pylori induces an array of pro-inflammatory cytokines in human gastric epithelial cells: quantification of mrna for interleukin-8, -1 alpha/beta, granulocyte-macrophage colony-stimulating factor, monocyte chemoattractant protein-1 and tumour necrosis factor-alpha. | despite the fact that helicobacter pylori is known to be non-invasive, mucosal infiltration of inflammatory cells have been observed in the gastric mucosa. the exact pathogenesis of such an inflammatory reaction has not been well defined. we explored the repertoire of cytokine genes expressed in human gastric epithelial cells in response to coculture with h. pylori. after gastric epithelial cells, snu-5 and kato iii, were infected with h. pylori, expression of several cytokine genes was assessed ... | 1997 | 9257236 |
| [serodiagnosis of helicobacter pylori infections by detection of immunoglobulin g antibodies with an immunoblot technique]. | serological testing has recently been proposed as an aid in diagnosis of h. pylori infections. in this study, an immunoblot method has been evaluated to diagnose h. pylori infection serologically by comparing 104 serum specimens from patients with a positive gram stain and/or culture result and a positive urease test on biopsy material, as well as 30 serum specimens from patients with negative urease test, and negative microscopy and culture results. thirteen bands could be identified by immunob ... | 1996 | 9275637 |
| evidence for recombination in the flagellin locus of campylobacter jejuni: implications for the flagellin gene typing scheme. | the flagellin subunit of the flagellar filament in campylobacter jejuni is encoded by two highly homologous tandem genes, flaa and flab. the flaa gene was sequenced in 18 strains of c. jejuni, including isolates from three outbreak groups. sequences obtained were compared with flaa sequences available in the genbank database, and all were analyzed for mosaic gene structure by using recently described statistical tests for detecting gene conversion among aligned sets of sequences. strong evidence ... | 1997 | 9276421 |
| rapid pcr with nested primers for direct detection of campylobacter jejuni in chicken washes. | rapid detection of campylobacter jejuni by pcr directly from foods, without prior growth steps, would be beneficial for the poultry industry. we have previously reported a pcr assay that allows detection of this bacterium after 48 h growth on campy cefex agar. we have now developed a more rapid nested pcr assay that specifically detects c. jejuni in chicken washes that have not undergone any lengthy growth steps prior to pcr. for the nested reaction, an external set of primers, c-1 and c-4, are ... | 1997 | 9281412 |
| economic costs and trade impacts of microbial foodborne illness. | this article presents the economic costs of foodborne diseases for selected countries, the approaches used to calculate these costs, and a discussion on the interaction between microbial food safety issues and international trade in food. the human illness costs due to foodborne pathogens are estimated most completely in the united states of america, where, each year, 7 foodborne pathogens (campylobacter jejuni, clostridium perfringens, escherichia coli o157:h7. listeria monocytogenes, salmonell ... | 1997 | 9282387 |
| effect of cytolethal distending toxin on f-actin assembly and cell division in chinese hamster ovary cells. | cytolethal distending toxin (cdt) is a newly described toxin produced by a number of enteropathogens, including campylobacter jejuni, various escherichia coli strains, and a few shigella species. cdt induces distension and eventual death of a number of transformed cell lines. here, we extend previous studies by demonstrating that morphological changes in cdt-treated chinese hamster ovary cells are coincident with changes in cytoskeletal structure and an inhibition of cell proliferation. cdt-trea ... | 1997 | 9284151 |
| [guillain-barré syndrome of axonal type, campylobacter jejuni infection and anti-ganglioside gm1 antibodies]. | infection by campylobacter jejuni (c. jejuni) has been reported in 17 to 55 p. 100 of the gbs. the "axonal" gbs has been recently attributed to such an association. it is characterized by rapid progression to severe widespread paralysis, respiratory failure, poor and delayed recovery. the acute "axonal" form of guillain-barré syndrome has been and remains a matter of controversy. a typical case of gbs with serological evidence of recent c. jejuni infection and increased antibodies to gm1 is repo ... | 1997 | 9296136 |
| norfloxacin resistance in campylobacter jejuni and campylobacter coli isolates from swedish patients. | this study focused on the frequency of campylobacter jejuni and campylobacter coli strains resistant to norfloxacin. included were 1659 consecutive stool specimens isolated between 1992 and 1995, from as many swedish patients with diarrhoea. the patients were divided with regard to place of infection and age. all strains were tested for susceptibility to norfloxacin by means of disc diffusion test on blood-agar plates. norfloxacin-resistant strains (n = 310) were furthermore tested for resistanc ... | 1997 | 9301992 |
| evaluation of antibodies reactive with campylobacter jejuni in egyptian diarrhea patients. | serum and stool samples were collected from 128 individuals: 96 diarrhea patients and 32 apparently healthy controls. stool specimens were cultured for enteric bacterial pathogens, while sera were screened by enzyme-linked immunosorbent assay for campylobacter jejuni-reactive antibodies. of 28 diarrhea patients who demonstrated c. jejuni-reactive antibodies (titers, > 100), 14 were culture positive for this organism. the 32 healthy controls showed significantly lower antibody titers (p < 0.05) w ... | 1997 | 9302201 |
| [infection of ascitic fluid by campylobacter jejuni in cirrhotic patients]. | 1997 | 9303616 | |
| induction of anti-gm1 ganglioside antibodies by campylobacter jejuni lipopolysaccharides. | a frequent association exists between acute motor neuropathy, antecedent campylobacter jejuni (cj) and anti-gm ganglioside antibodies. despite the chemical and immunological similarity between cj lipopolysaccharides (lps) and gm1, the mechanism of induction of anti-gm1 antibodies is still unclear. we used cj lps to immunize rats, mice and immunodeficient mice lacking in nk, cd8+ or t-cell populations. none of these animals developed significant anti-gm1 titers. however, rats immunized with keyho ... | 1997 | 9307238 |
| pore-forming molecules in gram-negative anaerobic bacteria. | little information is available about porin molecules in anaerobes. porins from bacteroides fragilis and porphyromonas, fusobacterium, and campylobacter species have been described. a pore-forming outer membrane (om) porin protein was isolated from b. fragilis (omp-200); it is exposed at the cell surface and dissociated by boiling and application of reducing agents. fusobacterium nucleatum foma, an om porin protein of 40 kd, had a deduced topology of foma similar to that of established porins, d ... | 1997 | 9310708 |
| pcr detection, identification to species level, and fingerprinting of campylobacter jejuni and campylobacter coli direct from diarrheic samples. | three sets of primers were designed for pcr detection and differentiation of campylobacter jejuni and campylobacter coli. the first pcr assay was designed to coidentify c. jejuni and c. coli based on their 16s rrna gene sequences. the second pcr assay, based on the hippuricase gene sequence, identified all tested reference strains of c. jejuni and also strains of that species which lack detectable hippuricase activity. the third pcr assay, based on the sequence of a cloned (putative) aspartokina ... | 1997 | 9316909 |
| serum antibodies against gangliosides and campylobacter jejuni lipopolysaccharides in miller fisher syndrome. | seven patients with miller fisher syndrome (mfs), six in the acute phase and one in the recovery phase, were investigated for serum antibodies against gangliosides and purified lipopolysaccharides (lps) from different strains of campylobacter jejuni, including the mfs-associated serotypes o:2 and o:23. immunoglobulin g antibodies against gangliosides gt1a and gq1b were found in five of six patients in the acute phase of disease. three of these patients also displayed antibodies to ganglioside gd ... | 1997 | 9317004 |
| distribution of serotypes of campylobacter jejuni and c. coli from danish patients, poultry, cattle and swine. | the number of human cases of enteritis caused by campylobacter jejuni and c. coli is increasing in denmark and other european countries. no systemic typing has earlier been performed on campylobacter isolates of danish origin. the primary purpose of this study was to provide a serotype distribution of campylobacter isolates from danish patients and the major food production animals. in addition, the occurrence of intestinal carriers of thermophilic campylobacters among these food production anim ... | 1997 | 9322068 |
| cloning and characterization of helicobacter pylori succinyl coa:acetoacetate coa-transferase, a novel prokaryotic member of the coa-transferase family. | sequencing of a fragment of helicobacter pylori genome led to the identification of two open reading frames showing striking homology with coenzyme a (coa) transferases, enzymes catalyzing the reversible transfer of coa from one carboxylic acid to another. the genes were present in all h. pylori strains tested by polymerase chain reaction or slot blotting but not in campylobacter jejuni. genes for the putative a and b subunits of h. pylori coa-transferase were introduced into the bacterial expre ... | 1997 | 9325289 |
| application of multiplex polymerase chain reaction for rapid identification of campylobacter jejuni and c coli associated with reproductive failure. | to evaluate a multiplex polymerase chain reaction (pcr) to distinguish campylobacter jejuni from c coli as causes of reproductive failure. | 1997 | 9328656 |
| antimicrobial susceptibility patterns of thermophilic campylobacter spp. from humans, pigs, cattle, and broilers in denmark. | the mics of 16 antimicrobial agents were determined for 202 campylobacter jejuni isolates, 123 campylobacter coli isolates, and 6 campylobacter lari isolates from humans and food animals in denmark. the c. jejuni isolates originated from humans (75), broilers (95), cattle (29), and pigs (3); the c. coli isolates originated from humans (7), broilers (17), and pigs (99); and the c. lari isolates originated from broilers (5) and cattle (1). all isolates were susceptible to apramycin, neomycin, and ... | 1997 | 9333055 |
| restriction fragment length polymorphism analysis and random amplified polymorphic dna analysis of campylobacter jejuni strains isolated from patients with guillain-barré syndrome. | campylobacter jejuni serotype o19 strains associated with the guillain-barré syndrome (gbs) and other strains were examined by restriction fragment length polymorphism (rflp) analysis of polymerase chain reaction products of the flaa genes and by random amplified polymorphic dna (rapd) analysis. rflp analysis showed that regardless of lio serotype, geographic origins, or association with gbs, the o19 isolates shared an identical digestion pattern by each of four restriction endonucleases, ddei, ... | 1997 | 9333178 |
| a longitudinal study of circulating lymphocyte subsets in the peripheral blood during the acute stage of guillain-barré syndrome. | activated t cells are implicated in the pathogenesis of guillain-barré syndrome (gbs). blood samples from 16 patients with gbs were studied with flow cytometry during the acute stage of their disease to define circulating lymphocyte populations. during the progressive phase of gbs the t-suppressor/inducer (cd4/cd45ra) subset was decreased (10.3 +/- 4.4%, p < 0.05) and the t-helper/ inducer (cd4/cd29) subset was increased (34.9 +/- 9.2%, p < 0.05) compared to sex and age matched patients with oth ... | 1997 | 9335007 |
| discrimination of campylobacter jejuni isolates by fla gene sequencing. | comparison of the entire coding sequence of flaa (1,764 nucleotides) from 15 isolates of campylobacter jejuni showed two regions of high variability, one region approximately from base positions 700 to 1,450 and a short variable region (svr) from base positions 450 to 600. parsimony analysis of the svr sequences yielded a dendrogram similar to that which was derived by analysis of the entire gene. pcr was used to generate templates, and the svr was sequenced with primers constructed to hybridize ... | 1997 | 9350739 |
| bacterial flavohaemoglobins: a consensus sequence and identification of a discrete enterobacterial group and of further bacterial globins. | the amino acid sequences of haemoglobin-like proteins from the bacteria alcaligenes eutrophus, bacillus subtilis, erwinia chrysanthemi, escherichia coli, vibrio parahaemolyticus, vitreoscilla sp. and the yeast saccharomyces cerevisiae were studied. phylogenies based on distance and parsimony analysis showed that the eubacterial group can be easily distinguished from the other haemoglobin-like proteins. the construction of a consensus bacterial flavohaemoglobin based on the alignment of six bacte ... | 1997 | 9351199 |
| acute hepatitis associated with campylobacter jejuni bacteraemia. | a case of acute hepatitis associated with campylobacter jejuni bacteraemia is reported. transaminase levels were increased over 50-fold in a patient with clinical features of enteritis and septicaemia. campylobacter jejuni was isolated from blood and faecal cultures. other infective and noninfective causes of acute hepatitis were excluded. the patient's symptoms and liver function values improved after antimicrobial therapy. hepatitis should be considered as a complication of human campylobacter ... | 1997 | 9352262 |
| humoral immune response against campylobacter jejuni lipopolysaccharides in guillain-barré and miller fisher syndrome. | in this study we characterized the igg antibodies against lipopolysaccharides (lps) of campylobacter jejuni in serum from patients with guillain-barré syndrome (gbs), miller fisher syndrome (mfs), c. jejuni enteritis and normal controls. in patients with gbs and mfs long-lasting titers of igg1 and igg3 antibodies against lps from gbs and mfs associated c. jejuni were found. the subclass and course of these antibodies were highly associated with those of antibodies against gm1 and gq1b in gbs and ... | 1997 | 9357448 |
| specific detection and confirmation of campylobacter jejuni by dna hybridization and pcr. | conventional detection and confirmation methods for campylobacter jejuni are lengthy and tedious. a rapid hybridization protocol in which a 1,475-bp chromogen-labelled dna probe (pdt1720) and campylobacter strains filtered and grown on 0.22-micron-pore-size hydrophobic grid membrane filters (hgmfs) are used was developed. among the environmental and clinical isolates of c. jejuni, campylobacter coli, campylobacter jejuni subsp. doylei, campylobacter lari, and arcobacter nitrofigilis and a panel ... | 1997 | 9361442 |
| detection of campylobacter jejuni invasion of hep-2 cells by acridine orange-crystal violet staining. | 1997 | 9361745 | |
| [a case of axonal form of guillain-barré syndrome associated with anti-gm1b igg antibody following penner 4 campylobacter jejuni infection]. | a 41-year-old woman was admitted to the hospital because of diarrhea followed by progressive weakness of all extremities and dysphagia. on neurological examination, she showed facial diplegia, bulbar palsy, flaccid quadriplegia, and absence of all deep tendon reflexes in addition to laségue's sign. the campylobacter jejuni penner type 4 was isolated from the culture of stool. the test of anti-gm1b antibody (igg) was positive in the serum. the protein content was elevated in the cerebrospinal flu ... | 1997 | 9366179 |
| produce handling and processing practices. | in the past decade, outbreaks of human illness associated with the consumption of raw vegetables and fruits (or unpasteurized products produced from them) have increased in the united states. changes in agronomic, harvesting, distribution, processing, and consumption patterns and practices have undoubtedly contributed to this increase. pathogens such as listeria monocytogenes, clostridium botulinum, and bacillus cereus are naturally present in some soil, and their presence on fresh produce is no ... | 1997 | 9366597 |
| historical overview of key issues in food safety. | foodborne transmission of pathogenic and toxigenic microorganisms has been a recognized hazard for decades. even half a century ago we knew about the dangers of botulism from underprocessed canned foods; staphylococcal poisoning from unrefrigerated cream-filled pastries, sliced ham, meat, and poultry salads; and salmonellosis from infected animal products. despite new protective measures, changes in preservation techniques and failure to follow recognized procedures have created new dangers. mor ... | 1997 | 9366600 |
| is undifferentiated seronegative spondyloarthropathy a forme fruste of reactive arthritis? | undifferentiated spondyloarthropathy (uspa) may either represent a forme fruste of other spondyloarthropathies like reactive arthritis or be a different disease entity. to study the link between uspa and reactive arthritis, we studied the presence of iga antibodies to yersinia enterocolitica, salmonella typhimurium, shigella flexneri, campylobacter jejuni and chlamydia trachomatis in sera from 14 patients with uspa (european spondyloarthropathy study group criteria) using elisa. escherichia coli ... | 1997 | 9376974 |
| both dna gyrase and reverse gyrase are present in the hyperthermophilic bacterium thermotoga maritima. | like all hyperthermophiles yet tested, the bacterium thermotoga maritima contains a reverse gyrase. here we show that it contains also a dna gyrase. the genes top2a and top2b encoding the two subunits of a dna gyrase-like enzyme have been cloned and sequenced. the top2a (type ii dna topoisomerase a protein) is more similar to gyra (dna gyrase a protein) than to parc [topoisomerase iv (topo iv) c protein]. the difference is especially striking at the c-terminal domain, which differentiates dna gy ... | 1997 | 9380682 |
| subtypes of campylobacter jejuni from sporadic cases of diarrhoeal disease at different locations in england are highly diverse. | serotyping (heat stable antigens) was performed on 398 strains of campylobacter jejuni from faeces of human enteritis cases in england. strains isolated over 12 months at three locations were heterogeneous with 33 hs serotypes represented. hs1 and hs4 complex were the predominant types (34% of all strains). the monthly strain frequency distributions were similar at the three locations. the late spring peak appeared to be associated with a rise in miscellaneous serotypes rather than with the emer ... | 1997 | 9384275 |
| acute diarrhea associated with campylobacter jejuni subsp. doylei in são paulo, brazil. | 1997 | 9384354 | |
| [antimicrobial activities of clarithromycin against recent obtained clinical isolates]. | in order to evaluate antimicrobial activities of clarithromycin (cam), minimum inhibitory concentrations (mics) of cam and control drugs were determined against clinical isolates that were obtained from outpatients in 1994 and 1996. the results are summarized as follows; 1. it was not showed that cam-resistant strains were increasing among staphylococcus spp., beta-streptococci, moraxella subgenus branhamella catarrhalis, haemophilus influenzae, bordetella pertussis, campylobacter jejuni subsp. ... | 1997 | 9394238 |
| [campylobacter jejuni enteritis in three patients with hiv infection]. | gatrointestinal symptoms, which include diarrhea, are as common as respiratory symptoms in patients with hiv infection. gastrointestinal symptoms may result from infections, neoplasma, hiv enteropathy or drug toxicity. three hiv-infected patients admitted to our hospital complaining of diarrhea and fever. we confirmed their diagnosis as campylobacter jejuni enteritis by bacteriological examination of their feces. all of them had eaten inadequately cooked meat in restaurants before the onset of t ... | 1997 | 9394561 |
| cloning and characterization of a campylobacter jejuni 72dz/92 gene encoding a 30 kda immunopositive protein, component of the abc transport system; expression of the gene in avirulent salmonella typhimurium. | three gene libraries of campylobacter jejuni 72dz/92 dna were prepared using lambda gt11, psupercos and pwsk129 cloning vectors. screening of the libraries with escherichia coli absorbed antiserum generated against whole c. jejuni revealed several immunoreactive clones of apparent molecular masses 19, 28, 30 and 50 kda. the most commonly isolated clones expressed 30 kda protein. the nucleotide sequence of the 1768 bp c. jejuni dna yielded one complete (orf2) and two partial open reading frames ( ... | 1997 | 9395059 |
| clinical and epidemiologic features of guillain-barré syndrome. | guillain-barré syndrome (gbs) is defined clinically as a peripheral neuropathy causing limb weakness that progresses for up to 4 weeks before reaching a plateau. the symptoms may be caused by inflammatory demyelination, axonal degeneration, or both. gbs occurs throughout the world, with a median incidence of 1.3 cases/100,000 population (range, 0.4-4.0). males are more commonly affected than females, and there are peaks in young adults and the elderly. there is no clear seasonal association in w ... | 1997 | 9396689 |
| guillain-barré syndrome: multifactorial mechanisms versus defined subgroups. | the clinical spectrum of guillain-barré syndrome (gbs) is summarized in relation to antecedent infections and anti-ganglioside antibodies. associations exist between a pure motor form of gbs, diarrhea, campylobacter jejuni infection, and anti-gm1 antibodies; between cranial nerve involvement and miller fisher syndrome, c. jejuni infection, and anti-gq1b antibodies; and between variants, such as severe sensory involvement and cytomegalovirus infection. these three clinical variants are suggested ... | 1997 | 9396690 |
| epidemiologic and clinical features of campylobacter jejuni infections. | gram-negative bacteria of the genus campylobacter and of related genera frequently colonize the gastrointestinal tracts of humans, other mammals, and birds. one organism, campylobacter jejuni, has been recognized as an important human pathogen, usually causing a diarrheal illness. infection is common throughout the world, but clinical and epidemiologic features differ in developed and developing countries. the high incidence of c. jejuni infections and their propensity to invade tissue and to in ... | 1997 | 9396691 |
| microbiologic approaches for studying campylobacter species in patients with guillain-barré syndrome. | campylobacter jejuni is now considered to be the most common cause of bacterial diarrheal disease in the united states. sufficient evidence exists to support the hypothesis that c. jejuni induces guillain-barré syndrome (gbs); however, many questions about the biology of the organism and host factors need to be answered. in order to study the role of c. jejuni and other campylobacter species as a cause of gbs, isolates from patients with different forms of gbs and appropriate control populations ... | 1997 | 9396692 |
| structure and conserved characteristics of campylobacter jejuni lipopolysaccharides. | the lipid a component of campylobacter jejuni lipopolysaccharides (lpss) contains the same architectural principle as that found in other bacterial species; however, unlike the case with other bacterial species, the lipid a backbone of c. jejuni strains is composed of a phosphorylated beta(1'-6)-linked disaccharide containing 2,3-diamino-2,3-dideoxy-d-glucose and d-glucosamine as the major molecular species. despite a backbone that differs structurally from that of classic enterobacterial lipid ... | 1997 | 9396693 |
| association between campylobacter infection and guillain-barré syndrome. | guillain-barré syndrome (gbs), a neurologic disease that produces ascending paralysis, affects people all over the world. acute infectious illnesses precede 50%-75% of the gbs cases. although many infectious agents have been associated with gbs, the strongest documented association is with campylobacter infection. the first line of evidence supporting campylobacter infection as a trigger of gbs is anecdotal reports. the second line of evidence is serologic surveys, which have demonstrated that s ... | 1997 | 9396695 |
| campylobacter jejuni isolates from japanese patients with guillain-barré syndrome. | serologic evidence of recent campylobacter jejuni infection was found in 92 (45%) of 205 japanese patients with guillain-barré syndrome (gbs), and 49% of those 92 patients also had antibodies to gm1. sixteen independent clinical isolates from gbs patients were serotyped: 12 belonged to penner's heat-stable (hs) o serotype hs-19, 3 to hs-2, and 1 to hs-4. of the patients whose c. jejuni isolates belonged to hs-19, 80% had elevated anti-gm1 antibodies. although the correlation was significant betw ... | 1997 | 9396696 |