Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| a chemically modified tetracycline (cmt-3) is a new antifungal agent. | several chemically modified tetracycline analogs (cmts), which were chemically modified to eliminate their antibacterial efficacy, were unexpectedly found to have antifungal properties. of 10 cmts screened in vitro, all exhibited antifungal activities, although their efficacies varied. among these compounds, cmt-315, -3, and -308 were found to be the most potent as antifungal agents. the mics of cmt-3 against 47 strains of fungi in vitro were determined by using amphotericin b (amb) and doxycycl ... | 2002 | 11959581 |
| current situation of tinea capitis in southeastern austria. | 2002 | 11973055 | |
| antimicrobial activities of a new schizozygane indoline alkaloid from schizozygia coffaeoides and the revised structure of isoschizogaline. | extracts from schizozygia coffaeoides showed antimicrobial activity against fungal and bacterial species. alkaloids isolated using bioassay-guided fractionation were isoschizogaline, schizogynine, and a new indoline alkaloid, 7,8-dehydro-19beta-hydroxyschizozygine, shown to be the most active antifungal compound. the structure of isoschizagaline, the only active antibacterial, is revised on the basis of nmr analysis. | 2002 | 11975502 |
| endemic scalp ringworm: an object lesson in control of a common fungal infection. | 2001 | 11979119 | |
| trichophyton violaceum is the dominant cause of tinea capitis in children in tripoli, libya: results of a two year survey. | the causative agents of tinea capitis in libyan nationals attending the out patient dermatology clinic of the tripoli medical centre over the period december 1997 to december 1999 were investigated. samples (hair and scalp scrapings) were taken from 940 patients who presented with suspected tinea capitis. the etiological agents were identified in 584 cases. trichophyton violaceum was found to be the most prevalent organism isolated being responsible for 64.4% (376/584) of culture positive cases, ... | 2002 | 11998877 |
| occurrence of keratinophilic fungi and dermatophytes on domestic birds in nigeria. | feathers, nails and beaks of one hundred and twenty common birds in nigeria, chicken [50], ducks [20], turkeys [15] and pigeons [35], were examined using the soil plate technique for their mycoflora. 15 species of fungi were recovered and they belong to the genera chrysosporium, trichophyton, microsporum, aspergillus, fusarium, mucor rhizopus, penicillium and trichoderma. microsporum gypseum was the species most frequently isolated (35% of the samples). the most common genus was chrysosporium an ... | 2002 | 12000131 |
| a randomized, double-blind, parallel-group, duration-finding study of oral terbinafine and open-label, high-dose griseofulvin in children with tinea capitis due to microsporum species. | tinea capitis, a common clinical pattern of dermatophyte infection in children is becoming a public health hazard in some countries. several studies have reported terbinafine to be a safe and well-tolerated fungicidal drug for the treatment of this infection. however, the optimal treatment duration for its use in the treatment of tinea capitis caused by microsporum species has not yet been determined. | 2002 | 12000378 |
| dermatophytes and other fungi associated with skin mycoses in tripoli, libya. | this study sought to determine the prevalence of skin infections and their causative agents in the libyan population. samples were collected from 2224 patients attending the dermatology clinics of the tripoli medical centre (tmc) between august 1997 and december 1999 and were submitted to a mycology laboratory for analysis. diagnosis was confirmed by microscopic examination in 1180 cases (53.1%) and the causative agent was isolated and cultured in 1160 cases (52.2%). dermatophytes, malassezia fu ... | 2002 | 12000510 |
| a study of dermatophytoses in sana'a, yemen republic. | the present study describes the extent and causative agents of dermatophytoses in sana'a, the capital of yemen republic. out of 1100 patients with various skin diseases, 16.6% were affected with dermatophytoses. among them, 70% were male and the age group 11-20 years was most susceptible to tinea infections. tinea corporis was the most common disease, followed by tinea capitis. one hundred and seventy isolates of dermatophytes related to 9 species were identified. microsporum canis was the most ... | 2002 | 12000511 |
| case report. rosacea-like tinea incognito. | we report a case of dermatophytosis of the face due to microsporum canis that was exacerbated and altered clinically by a long-term application of topical corticosteroids. we considered this case a rosacea-like tinea incognito of the beard area. | 2002 | 12000520 |
| skin scraping from a cat. | 2002 | 12019472 | |
| drug efficacy of terbinafine hydrochloride (lamisil) during oral treatment of cats, experimentally infected with microsporum canis. | cats represent a primary source of microsporum canis infections in humans. terbinafine hydrochloride (lamisil) is commonly used in the treatment of microsporosis in humans as its fungicidal action permits short periods of treatment. the aim of the present study was to estimate the efficacy of the drug in cats. nine cats were experimentally infected with m. canis and treated with terbinafine hydrochloride at a dose of 10-20 mg/kg (once daily, sid; low-dose group, ldg). another nine cats were simi ... | 2002 | 12019941 |
| tinea capitis in schoolchildren from lvory coast (western africa). a 1998-1999 cross-sectional study. | tinea capitis is a worldwide public health problem that poses specific therapeutic challenges. this dermatophytosis of the scalp is endemic in africa. the objectives of this study were to determine the prevalence, the associated demographic factors, causative species, and clinical types of tinea capitis in abidjan, ivory coast. | 2002 | 12031027 |
| proximal white subungual onychomycosis caused by microsporum canis in systemic lupus erythematosus. | we report the case of a mexican lupus patient who developed proximal white subungual onychomycosis on multiple toenails. microsporum canis was the causative agent. both nail invasion by m. canis and proximal white subungual onychomycosis are rare conditions indicative of an underlying immunodeficiency. | 2002 | 12036214 |
| production of extracellular enzymes by microsporum canis and their role in its virulence. | microsporum canis is the most prevalent dermatophyte of domestic animals. several enzymes produced by dermatophytes, particularly keratinases, are considered to play a role in the virulence of this fungus. to investigate the possible relationship between the clinical status of m. canis infection and enzymatic activity of isolates, we studied the relationship between keratinase, elastase, lipase and dnase levels produced in vitro by different isolates and virulence as expressed in a guinea pig mo ... | 2001 | 12054058 |
| in vitro susceptibility of microsporum canis and other dermatophyte isolates from veterinary infections during therapy with terbinafine or griseofulvin. | we investigated the in vitro activity of terbinafine against fresh veterinary isolates of microsporum canis and the potential of this organism to develop resistance in vivo during oral therapy. dermatophyte cultures (n = 300) were obtained from naturally infected cats and dogs undergoing oral therapy with terbinafine or griseofulvin. m. canis comprised 92% of isolates; other species included microsporum gypseum and trichophyton mentagrophytes. minimum inhibitory concentrations (mics) and minimum ... | 2002 | 12058731 |
| yeasts of the genus candida are the dominant cause of onychomycosis in libyan women but not men: results of a 2-year surveillance study. | the reported frequency of recovery of fungi from infected nails varies according to the geographical area. | 2002 | 12072073 |
| evaluation of the efficacy of oral lufenuron combined with topical enilconazole for the management of dermatophytosis in catteries. | the efficacy of oral lufenuron, a chitin synthetase inhibitor, combined with topical enilconazole, was evaluated for the management of microsporum canis infection in 100 cats housed in two catteries in france. the cats were treated with weekly rinses with enilconazole (0.2 per cent) for four weeks and, in each cattery, one group (a) was also treated with micronised griseofulvin (25 mg/kg administered orally twice a day for five weeks) and a second group (b) was treated with 60 mg/kg lufenuron ad ... | 2002 | 12081306 |
| use of the sensititre colorimetric microdilution panel for antifungal susceptibility testing of dermatophytes. | the sensititre yeastone antifungal panel was used to test 49 dermatophytes belonging to the species epidermophyton floccosum, microsporum gypseum, microsporum canis, trichophyton tonsurans, trichophyton rubrum, and trichophyton mentagrophytes. the mics of four antifungals obtained with the sensititre yeastone antifungal panel were compared with those obtained by the reference nccls microdilution method. the levels of agreement between the two methods (<or=2 dilutions) were 81.6% with amphoterici ... | 2002 | 12089289 |
| copper complexes with bioactive ligands. part ii--antifungal activity. | antifungal activity of new copper(ii) complexes of 2-methylthionicotinate (2-mesnic) of the composition cu(2-mesnic)2(menia)(2).4h2o (where menia is n-methylnicotinamide), and cu(2-mesnic)2(nia)(2).2h2o (where nia is nicotinamide) and cu(2-mesnic)2l2 (where l is isonicotinamide, inia, or ethyl nicotinate, etnic) were tested on various strains of filamentous fungi by the macrodilution method. most sensitive against copper(ii) adducts with bioactive ligands were rhizopus oryzae and microsporum gyp ... | 2002 | 12094729 |
| tinea capitis due to microsporum gypseum. | 2002 | 12095884 | |
| prevalence of tinea capitis as well as of asymptomatic carriers in school children in nablus area (palestine). | a study of tinea capitis was carried out during october 1998, involving 8531 school children aged 6-14 years (4718 males and 3813 females), attending 12 primary schools located in urban, rural, and refugee camp communities in the nablus district in the palestinian authority. a total of approximately 1389 of the school children aged 6-12 years (724 males and 665 females) were also surveyed on three occasions at 2-3 month intervals, over a 9-month period (october 1998-may 1999) using the hair brus ... | 2002 | 12100538 |
| report of two cases of tinea infection with scutula-like lesions caused by microsporum gypseum. | 2002 | 12100698 | |
| plumieride from allamanda cathartica as an antidermatophytic agent. | plumieride has been isolated as an active principle of the leaves of allamanda cathartica. it showed strong fungitoxicity against some dermatophytes causing dermatomycosis to animals and human beings. it exhibited a noncytotoxic nature against a p(388) mouse leukaemia cell line. | 2002 | 12112301 |
| [infectious skin diseases in childhood. 1: bacteria and fungi]. | infections may lead to a multitude of pathological skin alterations, and represent the most common diseases in pediatric dermatology. a prerequisite for successful treatment is an accurate diagnosis based on the medical history, clinical presentation and the culture of pathogens. of importance among the bacterial skin diseases in pediatrics are impetigo, scarlet fever, borreliosis and cat-scratch fever. dermatophytoses caused by trichophyton or species of microsporum affect either hair-bearing s ... | 2002 | 12136669 |
| infectious keratitis manifesting as a white plaque on the cornea. | 2002 | 12149067 | |
| [a method for group identification of hair infected with microsporum]. | a method for identifying the group appurtenance of biological objects from subjects suffering from various diseases is developed. the method can be used in examination of putrefactive objects (blood, secretions, hair, etc.) and in cases when the group appurtenance cannot be identified by other methods. | 2002 | 12165954 |
| [morphological study of human hair infected with microsporum canis]. | some aspects in forensic medical examination of hairs damaged by microsporum canis are discussed. the data of microscopic, fluorescent, and serological studies of damaged hairs and methods for their examination are presented. | 2002 | 12165955 |
| terbinafine: efficacy and tolerability in young children with tinea capitis due to microsporum canis. | we carried out an open, prospective, uncontrolled study to evaluate the efficacy and tolerability of terbinafine in the treatment of young children with tinea capitis due to microsporum canis. | 2002 | 12195561 |
| incidence of dermatophytes and cyclohexamide resistant fungi on healthy children hairs and nails in nurseries. | in order to estimate the prevalence of dermatophytes and other fungi on healthy children hairs and nails, 92 hair samples and 85 nail samples (groups of 10 finger nails from each child) were collected from 5 nurseries (children aged 9 months up to 4 years) in assiut city. from hair samples 22 species were collected, trichophyton (2 species) and microsporum (2 species) were the only recovered dermatophytes in addition to well known keratinophilic genus chrysosporium (4 species). from nail samples ... | 2002 | 12206316 |
| degradation of keratin substrates by fungi isolated from sewage sludge. | four fungal species including two dermatophytes and two saprophytes were isolated from sewage sludge samples at basrah (iraq) they were tested for their degradative ability towards three types of keratin substrates (human hair, chicken feathers and wool). the rate of keratin degradation was expressed as weight loss over three weeks of incubation using a liquid culture medium. human hair had the highest degradation rate by colonization of chrysosporium pannicola and microsporum gypseum at a rate ... | 2002 | 12206319 |
| stereoselective synthesis and in vitro antifungal evaluation of (e)- and (z)-imidazolylchromanone oxime ethers. | a series of (e)- and (z)-2, 3-dihydro-3-(1h-imidazol-1-yl)-4h-1-benzopyran-4-one oxime ethers have been synthesized and tested for antifungal activity. most compounds showed moderate to potent in vitro antifungal activity. among the tested compounds, compound (e)-3d was the most active agent against candida albicans and aspergillus niger, and compounds (z)-(3a) and (e)-3a were the most potent compounds against microsporum gypseum. detailed stereoselective synthesis, spectroscopic, and biological ... | 2002 | 12207281 |
| survey of dermatophyte infections in the lausanne area switzerland. | the dermatophytes are important in the swiss medical environment since 5-10% of consultations in dermatology concern mycotic infections. | 2002 | 12218248 |
| secreted metalloprotease gene family of microsporum canis. | keratinolytic proteases secreted by dermatophytes are likely to be virulence-related factors. microsporum canis, the main agent of dermatophytosis in dogs and cats, causes a zoonosis that is frequently reported. using aspergillus fumigatus metalloprotease genomic sequence (mep) as a probe, three genes (mep1, mep2, and mep3) were isolated from an m. canis genomic library. they presented a quite-high percentage of identity with both a. fumigatus mep and aspergillus oryzae neutral protease i genes. ... | 2002 | 12228297 |
| unusual presentation of microsporum canis in human hair. | this study reports an unusual presentation of microsporum canis in infected human hair in a three-year-old boy. infected hairs showed ectothrix colonization with a mass of small conidia and numerous macroconidia typical of the genus microsporum. the infected hairs also showed strong invasion by hyphae bearing small numbers of arthroconidia. these hyphae were thinner and longer than those normally found in hair and scalp. it is well known that in cases of tinea capitis due to m. canis, ectothrix ... | 2002 | 12230223 |
| antimicrobial and anti-inflammatory activity of folklore: mallotus peltatus leaf extract. | since ages mallotus peltatus (geist) muell. arg. var acuminatus (euphorbiaceae) leaf and stem bark is used in folk medicine to cure intestinal ailments and skin infections. in several intestinal ailments, localized inflammation is of common occurrence and hence we have evaluated the antimicrobial as well as anti-inflammatory activity of m. peltatus leaf extract. the crude methanol extract of m. peltatus leaves was found to be active against staphylococcus aureus, staphylococcus saprophyticus, st ... | 2002 | 12242000 |
| chemical analysis and antifungal activity of the essential oil of calea clematidea. | the chemical composition of the essential oils of calea clematidea baker obtained by hydrodistillation of the leaves and flowers was analysed by gc and gc/ms and the oils were assayed for their antifungal activities. the essential oil of the leaves showed a high content of a new natural epoxy terpenoid, named clemateol (ca. 70 %), with minor amounts of o-vanillin (6.5 %), spathulenol (4.2 %), alpha-terpinene (4.0 %), germacrene b (2.9 %), yomogi alcohol (1.8 %), ( e)-caryophylene (1.7 %), m-cyme ... | 2002 | 12357399 |
| characteristics of dermatophytoses in children treated at the department of dermatology and venerology, dr josip bencevic general hospital, slavonski brod, croatia, from february 1993 till february 2000. | dermatophytoses are common infections in children. during the period from february 1993 till february 2000, 308 children with dermatophytoses were examined at the department of dermatology and venerology, dr.josip bencević general hospital, slavonski brod, croatia. out of these 308 pediatric patients, there were 157 (50.97%) male and 151 (49.03%) female children aged 3 months to 15 years. microsporum spp. infection was detected in 251 (81.49%) and trichophyton spp. infection in 57 (18.51%) cases ... | 2002 | 12377108 |
| can zinc be used for the treatment of microsporum gypseum dermatitis in man as well as in sheep? | 2002 | 12385705 | |
| antifungal evaluation of bis mannich bases derived from acetophenones and their corresponding piperidinols and stability studies. | the development of resistance to current antifungal therapeutics drives the search for effective new agents. the fact that some acetophenone-derived mannich bases had shown antifungal activities in our previous studies led us to design and synthesize acetophenone-derived bis mannich bases, b1-b5, bis(beta-aroylethyl)methylamine hydrochlorides, to evaluate their antifungal activity. these bis mannich bases were then converted to the corresponding piperidinols, c1-c5, which are structural isomers ... | 2002 | 12392084 |
| isolation of a microsporum canis gene family encoding three subtilisin-like proteases expressed in vivo. | microsporum canis is the main agent of dermatophytosis in dogs and cats and is responsible for frequent zoonosis. the pathogenesis of the disease remains largely unknown, however. among potential fungal virulence factors are secreted keratinolytic proteases, whose molecular characterization would be an important step towards the understanding of dermatophytic infection pathogenesis. m. canis secretes a 31.5 kda keratinolytic subtilisin-like protease as the major component in a culture medium con ... | 2002 | 12406327 |
| did earthworms contribute to the parasitic evolution of dermatophytes? | the survival of dermatophyte species in the gut of four species of earthworms was studied by feeding the fungi to the earthworms. recovery of the dermatophyte species in culture from the guts was only possible for microsporum gypseum and chrysosporium keratinophilum. in the light of these findings, we presume that earthworms could have influenced the parasitic evolution of certain dermatophytes. | 2002 | 12421289 |
| safety and immunologic effects after inoculation of inactivated and combined live-inactivated dermatophytosis vaccines in cats. | to determine antidermatophyte immunologic effects of an experimental combined live-inactivated dermatophytosis vaccine (clidv) and a commercial inactivated dermatophytosis vaccine (idv) in cats and to evaluate adverse effects associated with administration of these vaccines. | 2002 | 12428663 |
| fluconazole downregulates metallothionein expression and increases copper cytotoxicity in microsporum canis. | azole antifungals are widely used to treat infections with dermatophyte fungi. whereas it is well established that this class of drugs interferes with fungal ergosterol synthesis, little is known about its potential other biological effects. here we report the isolation and structural organization of microsporum canis metallothionein gene and demonstrate that fluconazole is able to downregulate the baseline as well as copper-induced expression of this gene. since this effect occurred within 30 m ... | 2002 | 12470632 |
| involvement of tnf-alpha changes in human cancer development, prevention and palliative care. | cancer development and ageing are complex sciences. from the study on the process of rodent carcinogenesis, we identified tumor necrosis factor-alpha (tnf-alpha) as an important mediator of cancer development. this paper presents three clinical examples of tnf-alpha up-regulation: by cord factors of mycobacterium tuberculosis, such as trehalose 6-monomycolate, as an activator of protein kinase c and by a cord factor like fraction of microsporum canis obtained in the air inside houses in thailand ... | 2002 | 12470903 |
| fungal flora of human toe webs. | a total of 100 young adults (67 males and 33 females) participated in the study. clinical evaluation showed that only 10 of the volunteers showed some scaling, fissuring and peeling of the toe webs. four of these complained of occasional itching. fourteen different genera of fungi were recovered from 78 of the 100 youths screened. yeasts were recovered from 21 (27%) of the positive cases, nondermatophytes from 38 (49%) and dermatophytes from 19 (24%). microsporum gypseum was the most commonly re ... | 2002 | 12472726 |
| in vitro antimicrobial activity of ethanol and water extracts of cassia alata. | crude ethanol and water extract of leaves and barks from cassia alata were tested in vitro against fungi, (aspergillus fumigatus and microsporum canis), yeast (candida albicans) and bacteria (staphylococcus aereus and escherichia coli). c. albicans showed concentration-dependent susceptibility towards both the ethanol and water extracts from the barks, but resistant towards the extracts of leaves. the degree of susceptibility varied, the water extract from barks showed bigger inhibition zone tha ... | 2003 | 12499068 |
| [anti-yeast activity of ethanol extracts of lilium candidum l]. | the paper deals with anti-yeast activity of ethanolic extracts from the flowers and bulbs of lilium candidum l., liliaceae, as well as some compounds isolated from these extracts. several different methods were used for the determination of anti-yeast activity: lowry method of protein determination, dilution and cultivation method. the extract from the bulbs was shown to be more active than the extract from the flowers, while isolated compounds were inactive against the tested yeasts. | 2002 | 12501491 |
| in vitro antifungal activity of 3-phenyl-2h-benzoxazine-2,4(3h)-diones. | a series of 81 3-phenyl-2h-benzoxazine-2,4(3h)-diones with substitution at c(6) on the benzoxazine ring and on the phenyl moiety was synthesized; the compounds were evaluated for antifungal activity against five strains of potentially pathogenic fungi (absidia corymbifera, aspergillus fumigatus, candida albicans, microsporum gypseum and trichophyton mentagrophytes). structure-activity relationships against t. mentagrophytes and m. gypseum were determined using the free-wilson method, which was f ... | 2002 | 12503392 |
| fluconazole in the treatment of pediatric tinea capitis caused by microsporum canis. | fluconazole has been shown to be effective in the treatment of fungal scalp infections in children; however, there is limited experience of its use in microsporum scalp infections. we studied 11 children with tinea capitis caused by microsporum canis who received oral fluconazole at a dose of 5-7.5 mg/kg/day for 6 weeks. mycological cure was observed in two of the 11 patients at week 4 from the start of therapy, in four patients at week 8 and in three patients at week 16. one of the remaining pa ... | 2002 | 12512234 |
| [an outbreak of tinea capitis in a child care center]. | we describe an outbreak of tinea capitis in a kindergarten. individuals with relation to the institution were examined clinically and mycologically (n = 98). microsporum audouinii was cultured from 12 people, out of whom eight patients had tinea capitis and seven patients had tinea corporis. three patients had both tinea capitis and tinea corporis. the problems with spread of anthropophilic infections and the difficulties with treatment of microsporum dermatophytes are discussed. | 2002 | 12523227 |
| [chemical constituents of the essential oil from the fruits of lindera glauca and its antifungal activities]. | the chemical constituents of the two essential oils extracted from the fruits of lindera glauca by hydrodistillation and petroleum ether have been studied by means of gc-ms. among which, 32 kinds of constituents were identified in distilling oil and 22 kinds in solvent oil. the main components in distilling oil were n-carpric acid (25.39%), germacrene a (10.71%), n-dodecanole acid (10.08%), epishyobunol acetate (7.29%) and caryophyllene oxide (5.44%), and in solvent oil were camphene (17.55%), 3 ... | 1999 | 12575067 |
| [study on the inhibitory activity, in vitro, of baicalein and baicalin against skin fungi and bacteria]. | in this paper, we concentrated in examining, in vitro, the antiseptic activity of the baicalein and baicalin upon the seventeen pathogenic skin fungal and sixteen skin bacterial strains, these two flavonic compounds were known principally as the biosubstances of a traditional chinese medicinal plant: scutellaria baicalensis. in agar media, the baicalein possessed potent specific activity against the pathogenic yeasts with mics of 70-100 micrograms/ml; but in the same condition, no inhibitory eff ... | 2000 | 12575154 |
| tinea capitis in cleveland: survey of elementary school students. | tinea capitis, a fungal infection of the scalp, is of increasing public health importance, and trichophyton tonsurans has become the primary causative agent in north america. | 2003 | 12582387 |
| the fungicidal activity of novel nanoemulsion (x8w60pc) against clinically important yeast and filamentous fungi. | surfactant nanoemulsions are water in oil preparations that proved to have a broad spectrum biocidal activity against a variety of microorganisms including gram-positive and gram-negative bacteria, spores and enveloped viruses. these preparations are non-toxic to the skin, mucous membrane and gastrointestinal tissues at biocidal concentrations. in this study, 0.1% of the nanoemulsion designated x8w60pc has shown fungicidal activity against yeast including candida albicans and c. tropicalis in 15 ... | 2002 | 12650595 |
| dermatophytes isolated from patients in university hospital, kuala lumpur, malaysia. | a total of 576 dermatophytes were isolated from patients with a variety of skin infections from january 1993 to may 2000. ten species of dermatophytes were identified: epidermophyton floccosum (0.7%), microsporum audouinii (1.1%), m. canis (3.1%), m. gypseum (0.3%), trichophyton concentricum (3.5%), t. equinum (0.2%), t. mentagrophytes (36.1%), t. rubrum (53.8%), t. verrucosum (0.2) and t. violaceum (1.0%). the body sites most frequently affected by dermatophytes were the buttocks, nails and tru ... | 2002 | 12650596 |
| direct detection of dermatophytes in skin samples based on sequences of the chitin synthase 1 (chs1) gene. | for the direct detection of dermatophytes in skin scrapings and hairs from animals, a primer pair specific to the chitin synthase 1 (chs1) gene of dermatophytes was constructed. by pcr analysis with the primer pair, dermatophyte dna could be diagnosed directly and rapidly in clinical skin samples. | 2003 | 12655126 |
| synergistic inhibition of the growth in vitro of microsporum canis by miconazole and chlorhexidine. | an agar dilution technique was used to assess the minimum inhibitory concentrations (mic) of miconazole, chlorhexidine and a 1:1 combination of both agents for 10 isolates of microsporum canis. for nine of 10 of the isolates, a combination of miconazole and chlorhexidine was more effective than either agent alone; fractional inhibitory concentration indices indicated a synergistic effect for five isolates and an additive effect for four. these results illustrate the potent antimycotic effect of ... | 2003 | 12662267 |
| characteristics of superficial mycoses in malta. | a study was conducted to determine the chief agents of superficial mycoses in malta. data were collected over a 5-year period from mycologic investigations carried out on all dermatologic specimens sent to the mycology laboratory at st. luke's hospital in malta. | 2003 | 12694490 |
| a study of dermatophytes and their in-vitro antifungal sensitivity. | of the 150 clinically suspected cases of dermatophytosis studied, majority of the cases were from age group 11-20 and 21-30 (51.4%), tinea corporis (48.7%) and tinea capitis (18%) were the commonest clinical types. the isolation rate was 24% (36) of which 19 (52.7%) were trichophyton rubrum, 11 (30.55%) were trichophyton mentagrophytes and 4 (11.1%) were trichophyton violaceum. one isolate each of microsporum gypseum & epidermophyton floccosum were obtained. griseofulvin proved to be the best dr ... | 2002 | 12696733 |
| antifungal activity of essential oils from leaves and flowers of inula viscosa (asteraceae) by apulian region. | some essential oils from several plants (artemisia verlotorum, lavandula augustifolia, ocimum gratissimum) have proved to have acaricidal, antifungal and antibacterial activity. inula viscosa ait. (asteraceae), a plant growing spontaneously in the mediterranean area, is currently used by popular medicine for its therapeutic effects. flavonoids, azulenes, sesquiterpenes, and essential oils have been isolated and identified from its leaves. this paper reports the results of the composition and ant ... | 2002 | 12701377 |
| an outbreak of tinea capitis in a child care centre. | we describe an outbreak of tinea capitis in a kindergarten. individuals with relation to the institution were examined clinically and mycologically (n-98), microsporum audouinii was cultured from 12 people, out of whom eight patients had tinea capitis, four patients had tinea corporis, and three patients had both. the problems with spread of anthropophilic infections and the difficulties with treatment of microsporum dermatophytes are discussed. | 2003 | 12705146 |
| tinea capitis in a newborn infected by microsporum audouinii in spain. | 2003 | 12705769 | |
| dermatophytes isolated from symptomatic dogs and cats in tuscany, italy during a 15-year-period. | between january, 1, 1986 and december, 31, 2000, dermatological specimens from 10.678 animals (7.650 cats and 3.028 dogs) were examined for dermatophytes. all the animals presented clinical signs of ringworm. two thousand-four hundred fifty-six of the 10.678 (23%) examined animals scored positive for dermatophytes, 566 out of 3.028 canine (18.7%) and 1890 out of 7.650 feline specimens (24.7%). microsporum canis constituted 83% and 97% of the isolated dermatophytes respectively in dogs and cats, ... | 2002 | 12715942 |
| [clinical and epidemiological survey of dermatophytoses in jaen (spain)] | prevalence of dermatophytosis, with respect to age and sex and dermatophyte species, in jaen was investigated during a period of three years (1996-1999). the prevalence of dermatophytosis over three years was 4.48 cases / 1000 inhabitants. the isolated species were: microsporum canis (48.6%), trichophyton mentagrophytes (27.1%), epidermophyton floccosum (10%), trichophyton rubrum (8.6%), trichophyton violaceum (4.3%), and microsporum gypseum (1.4%). the most frequently observed dermatophytoses w ... | 2002 | 12716229 |
| in vitro antagonistic activity of monoterpenes and their mixtures against 'toe nail fungus' pathogens. | the antibiotic effect of the active ingredients in meijer medicated chest rub (eucalyptus oil, camphor and menthol) as well as the inactive ingredients (thymol, oil of turpentine, oil of nutmeg and oil of cedar leaf) were studied in vitro using the fungal pathogens responsible for onychomycosis, such as the dermatophytes tricophyton rubrum, trichophyton mentagrophytes, microsporum canis, epidermophyton fl occosum and epidermophyton stockdale. the zones of inhibition data revealed that camphor (1 ... | 2003 | 12722144 |
| parmelia cirrhatum: a potential source of broad spectrum natural antifungal. | during antifungal screening of some plants, the water extract of lichen, parmelia cirrhatum was found to be most effective against tested pathogenic fungi at the range of 60-80 microl/ml concentrations. the extract showed heavy doses of inoculum potential at 80 microl/ml and the antifungal activity of the extract did not expire up to 24 months of storage. the extract did not showed any irritation on mammalian skin up to 10% concentration. thus, the water extract of parmelia cirrhatum can be used ... | 2003 | 12722148 |
| effects of lufenuron treatment in cats on the establishment and course of microsporum canis infection following exposure to infected cats. | to determine effects of lufenuron treatment in cats on the establishment and course of microsporum canis infection following exposure to infected cats. | 2003 | 12725307 |
| fluorescent method for studying the morphogenesis and viability of dermatophyte cells. | the dermatophyte microsporum canis is commonly isolated from human and animal infection. the morphogenesis of this fungus was studied during its developmental stages through the fluorescent method fluorescein diacetate and ethidium bromide. to this end, 50 microl dermatophyte suspension were transferred onto cellophane wrapping esterilized discs (2.5 cm of diameter) placed over the surface of sabouraud dextrose agar on petri dishes and incubated at 25 degrees c for 30 days. every 60 minutes duri ... | 2003 | 12733625 |
| incidence of keratinophilic fungi from selected soils of kerala state (india). | one hundred and fifty-eight soil samples were collected from various areas of four districts of kerala and screened for prevalence of keratinophilic fungi and related dermatophytes. from the positive samples (60.75%), a total of eight genera with 15 species were isolated viz., arthroderma simii (0.63%), chrysosporium indicum (20.25%), c. keratinophilum (6.96%). c. lobatum (1.26%), c. pannicola (1.26%), c. tropicum (5.06%), chrysosporium state of arthroderma cuniculi (1.26%), chrysosporium state ... | 2002 | 12749581 |
| ecology of dermatophytes and other keratinophilic fungi in swimming pools and polluted and unpolluted streams. | the biodiversity and richness of keratinophilic fungal communities including dermatophytes were assessed in three stream sites and three swimming pools in the nablus district in palestine, using hair baiting (hbt) and surface dilution plate (sdp) techniques, over 8- and 6-month periods, respectively. the effect of wastewater effluent and selected ecological factors on these fungi in relation to species diversity and population densities were also considered. fifty keratinophilic fungal species w ... | 2002 | 12749584 |
| molecular taxonomy of dermatophytes and related fungi by chitin synthase 1 (chs1) gene sequences. | in the present study, the nucleotide sequences of the chs1 gene from dermatophytes and related fungi in the genera chrysosporium, epidermophyton, microsporum and trichophyton were investigated using molecular methods. about 440-bp genomic dna fragments of the chs1 gene from 21 species were amplified by polymerase chain reaction (pcr) and sequenced. the chs1 nucleotide sequences of these fungi showed more than 83% similarity. the molecular taxonomy of the chs1 gene sequences revealed that microsp ... | 2003 | 12755475 |
| which drug is most effective in treating childhood tinea capitis caused by microsporum species? | 2003 | 12765508 | |
| the prevalence of immediate and delayed type hypersensitivity reactions to microsporum canis antigens in cats. | spontaneous recovery from microsporum canis infections in cats is thought to be dependent on the development of a competent immune response. the purpose of this study was to determine the prevalence of positive delayed type hypersensitivity reactions in cats with and without dermatophytosis. four groups of cats were intradermally skin tested with m canis extract and test sites were evaluated both subjectively and objectively at 0, 24 and 48 h after injection. delayed intradermal testing (idt) re ... | 2003 | 12765626 |
| tinea capitis in brussels: epidemiology and new management strategy. | we found pre-established directives inadequate to cope with the current increase in anthropophilic tinea capitis in brussels. | 2003 | 12771493 |
| differentiating the dermatophytes. | 2002 | 12778950 | |
| antifungal activity of sterols and triterpenes isolated from ganoderma annulare. | three sterols, 5alpha-ergost-7-en-3beta-ol, 5alpha-ergosta-7,22-dien-3beta-ol and 5,8-epidioxy-5alpha,8alpha-ergosta-6,22-dien-3beta-ol and five triterpenes, applanoxidic acids a, c, f, g and h, have been isolated from ganoderma annulare. the applanoxidic acids a, c and f were found to inhibit the growth of the fungi microsporum cannis and trichophyton mentagrophytes at concentrations of 500 to 1000 microg/ml. | 2003 | 12781809 |
| anti dermatophytic activity of azardirachta indica (neem) by invitro study. | the leaf and seed extracts of the plant azardirachta indica were tested for antidermatophytic activity against dermatophytes such as trichophyton ruberum, trichophyton, mentagrophytes, trichophyton violaceum, microsporum nanum and epidermophyton floccosum by tube dilution technique. the minimum inhibitory concentration (mic) of neem seed extract was found to be lower tan that of neem leaf when tested against different species of dermatophytes. | 2002 | 12785173 |
| dermatomycoses in the rijeka area, croatia, before, during and after the war 1990-1999. | the frequency of dermatomycoses as well as the spectrum of causative agents in the rijeka area, northwestern part of croatia, in the periods before and during the war (1990-1994) and in the postwar period (1995-1999) were analyzed. a total of 20 463 patients with clinically suspected dermatomycoses referred to the department of dermatovenerology, clinical hospital center rijeka, was examined. in the period from 1990 till 1994, 2462 samples were positive, compared with 2250 positive samples durin ... | 2003 | 12801365 |
| prevalence of tinea capitis in primary schools in turkey. | the aim of our study was to determine the prevalence of tinea capitis in middle anatolia. between february 2000 and april 2000, a school survey of 4760 primary school children was carried out and 34 cases of tinea capitis were clinically diagnosed. sixteen (0.3%) of them were diagnosed both clinically and using culture. eighteen cases (52.9%) were diagnosed microscopically whereas the remaining 16 cases (47.0%) had a clinical diagnose. we also isolated and identified the following species of fun ... | 2003 | 12801366 |
| dermatophytes isolated from domestic animals in iran. | between 1994 and 1998, a total of 790 feather, hair and skin specimens from a variety of animals with suspected dermatophytoses were studied, of which 248 (31.4%) yielded dermatophytes. the most frequent dermatophytes isolated were microsporum canis (38.3%), trichophyton verrucosum (31.8%), t. mentagrophytes (13.3%) and m. gypseum (7.7%). there was a significantly higher proportion of positive cultures from cats (54.8%) than dogs (8.2%), and m. canis was the most common species isolated (87.2 an ... | 2003 | 12801367 |
| [prevalence of zoophilic dermatophytes in the sarajevo region]. | zoophlic dermatophytes are common cause of tinea infections in europe, especially in mediterranean area. the aim of our study was to determine the prevalence of zoophilic dermatophytes in sarajevo area, during a five-year period (1998-2002). samples (skin scrapings or nail fragments) were taken from 2,142 patients who presented with suspected dermatophytoses and cultured on sabouraud agar. after three weeks of incubations 465 (21.7%) dermatophytes were identified based on macroscopic and microsc ... | 2003 | 12822383 |
| [three years incidence of dermatophytes in a hospital in porto (portugal)]. | we evaluated the incidence of dermatophytes isolated at our hospital in the years of 1997 to 2000 and correlated it with anatomical site and age. trichophyton rubrum was the predominant species in all anatomical sites, excluding scalp, followed by microsporum canis, the leading agent of tinea capitis. all dermatophytosis, except tinea capitis by m. canis and trichophyton schoenleinnii appeared mainly in adult patients. our results revealed no substantial differences to other portuguese studies r ... | 2002 | 12825982 |
| antifungal activity of the methanolic extract and alkaloids of glaucium oxylobum. | the methanolic extract and total alkaloids of the aerial parts of glaucium oxylobum exhibited good activity against microsporum gypseum, microsporum canis, trichophyton mentagrophytes and epidermophyton floccosum. four alkaloids, dicentrine, glaucine, protopine, and alpha-allocryptopine, were identified as the compounds responsible for the antifungal activity of this plant. | 2003 | 12837370 |
| [dermatomycoses in the cat]. | 2003 | 12843846 | |
| onychomycosis in systemic lupus erythematosus: a case control study. | immunosuppressed patients are prone to develop onychomycosis. in systemic lupus erythematosus (sle) there are no previous studies. we aimed to establish the prevalence, clinical characteristics, and organisms causing onychomycosis in sle patients compared with controls. | 2003 | 12858446 |
| flurbiprofen, a unique non-steroidal anti-inflammatory drug with antimicrobial activity against trichophyton, microsporum and epidermophyton species. | the objective of this study was to determine the antifungal activity of flurbiprofen against dermatophytes like trichophyton, microsporum and epidermophyton species. | 2003 | 12859660 |
| inhibition of dermatophytes by optical brighteners. | the aim of this study was to investigate a possible effect of optical brighteners on the growth of dermatophytes. typical strains of trichophyton rubrum, t. mentagrophytes, microsporum canis and epidermophyton floccosum were grown on agar plates containing two different brighteners of stilbenedisulfonic acid type in concentrations between 5 x 10(-5) and 1 x 10(-2) mol l-1 and their thallus diameters were compared with controls. in addition, hyphae grown with brighteners were compared with contro ... | 2003 | 12870200 |
| synthesis and antimicrobial properties of 3-aryl-1-(1,1'-biphenyl-4-yl)-2-(1h-imidazol-1-yl)propanes as 'carba-analogues' of the n-arylmethyl-n-[(1,1'-biphenyl)-4-ylmethyl])-1h-imidazol-1-amines, a new class of antifungal agents. | a new series of 3-phenyl-1-(1,1'-biphenyl-4-yl)-2-(1h-imidazol-1-yl)propane derivatives 2a-l (related to the antifungal bifonazole) was synthesized and tested for antimicrobial activity. a number of substituents on the phenyl ring were chosen to compare the relative biological properties with those of corresponding aza-analogues, previously described by us. the in vitro antifungal activities of the newly synthesized azoles were tested against several pathogenic fungi responsible for human diseas ... | 2003 | 12875886 |
| recombinant expression and antigenic properties of a 31.5-kda keratinolytic subtilisin-like serine protease from microsporum canis. | a secreted 31.5-kda keratinolytic subtilase (sub3; aj431180) is thought to be a microsporum canis virulence factor and represents a candidate for vaccination trials. in this study, the recombinant keratinase (r-sub3) was produced by the pichia pastoris expression system and purified to homogeneity. recombinant sub3 displayed identical biochemical properties with the native protease. experimentally cutaneously infected guinea pigs showed specific lymphoproliferative response towards r-sub3, while ... | 2003 | 12900052 |
| [two cases of tinea capitis by microsporum ferrugineum believed infected in myanmar]. | we report two cases of tinea capitis by microsporum (m) ferrugineum. a two year old boy (case 1) visited our hospital 3 months after his return from myanmar. about a year later, we observed the same symptom on the scalp of his mother (case 2). in both cases itraconazole was effective clinically and mycologically. in japan, although m. ferrugineum was the most common organism of tinea capitis before the 1960s, no cases of tinea are found caused by this species nowdays. we believe these cases to h ... | 2003 | 12913810 |
| [analysis of dermatophyte flora at a private clinic in sapporo during the period 1992 to 2001]. | statistical analysis was made of a total of 5530 patients (6798 cases) of dermatophytoses presenting at our private clinic during the period 1992 to 2001. the number of patients and cases represents 8.0% and 9.8% of the entire outpatient population during that time, respectively. sex ratio (male/female) was 1.5. among the 6798 dermatophytoses cases, tinea pedis was most frequent (65.8%), followed by tinea unguium (20.7%), tinea cruris (7.2%), tinea corporis (3.9%), tinea manuum (2.4%) and tinea ... | 2003 | 12913811 |
| tinea corporis due to microsporum gypseum in a cat fancier. | 2003 | 12928537 | |
| [study of the cerbiden spectrum of antifungal activity against fungi pathogenic to humans]. | a comparatively wide spectrum of cerbiden antifungal activity against the fungi pathogenic for human has been determined. cerbiden is active against clinical and museum strains of candida spp. and other yeasts; trichophyton spp., microsporum spp. of dermatophytaceae family, museum strains of some species from mucor, rhizopus, rhizomucor genera of mucoraceae family; and it is not active with respect to studied fungi of aspergillus and penicillium genera of moniliaceae family. | 2003 | 12945196 |
| abbreviated oral itraconazole therapy for tinea corporis and tinea cruris. | the present study was designed to determine the lowest dose of orally administered itraconazole and the shortest duration of therapy necessary for treatment of tinea corporis and tinea cruris. for all patients, the itraconazole dose was 100 mg twice a day immediately after meals. twenty-eight patients received itraconazole on days 1 and 8, 12 patients received itraconazole on days 1 and 2, and five patients received itraconazole only on day 1. clinical and mycological evaluations were performed ... | 2003 | 12950901 |
| presence of dermatophytes on the nails of tinea capitis patients. prospective study in the area of sfax (tunisia). | between january 1995 and december 2000, 512 cases with mycologically confirmed tinea capitis have been diagnosed in our laboratory. in addition, finger nail samples have been taken from 211 patients out of 512. the culture of the nail samples taken was positive for 80 patients (38%). the isolated dermatophytes were the same in the nails and the scalp. microsporum canis was isolated in 82% of nail samples. trichophyton violaceum grew only in 18% and trichophyton quinckeanum in one case. a t. viol ... | 2003 | 12950904 |
| isolation of dermatophytes and non-dermatophytic fungi from soil in nigeria. | a total of 60 soil samples were collected from ifite awka, nnamdi azikiwe university and amawbia, all located in awka urban, anambra state, nigeria. an additional sample was collected from a household rug-carpet vacuum cleaner from a house located in enugu city, enugu state (a neighbouring state). the 61 samples were investigated for the occurrence of dermatophytic and non-dermatophytic fungi, using the hair-bait technique and agar dilution procedure. the medical importance of the isolates in th ... | 2003 | 12950905 |
| antimycobacterial and antifungal isosters of salicylamides. | a set of 40 derivatives of 3-hydroxypicolinic acid and 2-sulfanylbenzoic acid, isosteric to salicylanilides was synthesized. the compounds were evaluated for in vitro activity against mycobacterium tuberculosis, mycobacterium kansasii and mycobacterium avium, candida albicans, candida tropicalis, candida krusei, candida glabrata, trichosporon beigelii, aspergillus fumigatus, absidia corymbifera, trichophyton mentagrophytes and microsporum gypseum. structure-activity relationships of antimycobact ... | 2003 | 12953220 |
| [tinea capitis et corporis due to microsporum canis in an immunocompromised female adults patient]. | tinea capitis as well as tinea corporis in adults may occur under conditions of immunosuppression. if suspected clinically, direct microscopy and examination by culture is indispensable. therapeutic intervention should start without delay. a proven fungal infection of scalp hairs warrants immediate initiation of systemic treatment. hereby prevention of disfiguring hair loss, permanent formation of scar tissue, spread of fungal organisms to other cutaneous regions as well as infection of other pe ... | 2003 | 12955848 |
| [the change of dermatophyte spectrum in dermatomycoses]. | the spectrum of dermatophytes out of mycotic skin lesions had changed in last 70 years. before the second world war in germany microsporum audouinii and epidermophyton floccosum held the first position, since the fifties of last century trichophyton rubrum is the most frequently isolated dermatophyte accounting for 80-90% of the strains, followed by t. mentagrophytes. this development is typical for central and north europe and is connected with the increase in the incidence of tinea pedis. in c ... | 2003 | 12955853 |