Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| new insight in the mechanism of omeprazole antimicrobial combinations to eradicate helicobacter pylori. | 1995 | 7717343 | |
| ph and cure of h. pylori infection: it is difficult to have insights when one is in the dark. | 1995 | 7717344 | |
| helicobacter pylori and serum pepsinogen a, pepsinogen c, and gastrin: a methodological note. | 1995 | 7717349 | |
| eradication of helicobacter pylori infection in primary low-grade gastric lymphoma of mucosa-associated lymphoid tissue. | to determine the effect of eradicating helicobacter pylori infection on the course of low-grade gastric mucosa-associated lymphoid tissue (malt) lymphoma. | 1995 | 7717599 |
| [clinical study on helicobacter pylori infected chronic gastritis treated with supplementing qi and promoting blood circulation drugs]. | the syndrome of qi deficiency and blood stasis of chronic gastritis infected by helicobacter pylori (hp) was treated with the principle of supplementing qi and promoting blood circulation. the clinical symptoms, inhibiting and killing of hp and pathohistological study have been observed. it was proved that the treatment could improve the clinical symptoms, reduce the infiltration of inflammatory cells and ameliorate the hyperemia and edema of gastric mucosa. its inhibition and killing of hp was ... | 1994 | 7719103 |
| [gastric cancer in taiwan]. | the study of gastric cancer is important in clinical medicine as well as in public health. environmental factors play an important role in gastric carcinogenesis and thus primary prevention is feasible after improvement of these factors. the 5-year survival rate of resected early gastric cancer is over 90% and this provides an excellent paradigm for secondary prevention. though its mortality rate has declined since 1970, gastric cancer remains common and carries a high mortality in taiwan where ... | 1994 | 7719165 |
| significance of rapid urease test for identification of helicobacter pylori in comparison with histological and culture studies. | helicobacter pylori in the stomach is an etiological factor of gastritis and peptic ulcer. it is now considered that gastric cancer can be, at least in some cases, a late complication of h. pylori infection. in 123 consecutive endoscopic antral biopsies obtained from patients with the okamoto hospital, the specimens were subjected to the rapid urease test (rut), histology (h&e stain), and culture, for the identification of h. pylori. the results of these methods were compared semi-quantitatively ... | 1995 | 7719409 |
| protection of cultured rat gastric cells against oxidant stress by iron chelation. role of lipid peroxidation. | reactive oxygen metabolites may be involved in the pathogenesis of ethanol-, nonsteroidal antiinflammatory drug-, helicobacter pylori-, or ischemia/reoxygenation-induced gastric mucosal injury in vivo. iron plays a critical role in mediating oxidant injury in vitro. the present study examined a possible role of lipid peroxidation in inducing oxidant damage by determining the effect of iron chelation on cytotoxicity and on lipid peroxidation in cultured rat gastric cells. cytotoxicity was quantif ... | 1995 | 7720485 |
| helicobacter pylori gastritis therapy with omeprazole and clarithromycin increases serum carbamazepine levels. | an antibiotic combination that includes a proton pump inhibitor such as omeprazole and an antibiotic such as clarithromycin is likely to become the new standard regimen for treatment of helicobacter pylori gastritis because this combination is extremely effective and very well tolerated. the current report highlights a potentially significant pharmakokinetic drug interaction between clarithromycin and carbamazepine in two patients with long-standing epilepsy who were given such therapy for helic ... | 1995 | 7720489 |
| limitation of histology for detecting helicobacter pylori. | 1995 | 7721013 | |
| non-steroidal anti-inflammatory drugs (nsaid) cause gastrointestinal ulcers mainly in helicobacter pylori carriers. | 1995 | 7721023 | |
| postoperative alkaline reflux gastritis following vagotomy. | this study was undertaken to evaluate the incidence and severity of postoperative alkaline reflux gastritis in 798 symptomatic duodenal ulcer patients who had undergone vagotomy. the condition was identified on the basis of the unique endoscopic and histological findings in 116 (14.5%) of them. it was more frequent and severe in patients with truncal vagotomy and gastrojejunostomy than in those with truncal vagotomy and pyloroplasty, while it was not at all observed in cases with proximal gastri ... | 1994 | 7721240 |
| effect of helicobacter pylori on dbc-amp stimulated acid secretion by human parietal cells. | this study examines the effect of different h.p. strains (a-d) on dbc-amp stimulated acid secretion by human parietal cells in vitro. h.p. strains a and d reduced acid secretion dose-dependently between 20 and 80%. in contrast, h.p. strains b and c had little or no effect. we conclude that h.p. strains vary in their ability to suppress acid secretion, and that the site of inhibition lies beyond the c-amp level, possibly involving the k+h(+)-atpase of the parietal cell. interference with acid sec ... | 1994 | 7721241 |
| the prevalence of helicobacter pylori positivity in a symptom-free population, aged 1 to 40 years. | epidemiologic data about the prevalence of helicobacter pylori positivity as determined by serology are presented in a large series of asymptomatic subjects (n = 1046). serology is nowadays generally accepted as a valid non-invasive screening method for the detection of a helicobacter pylori infection. blood samples were taken from apparently healthy children (n = 480; aged 1-17 years) and pregnant women (n = 566; age 18-40 years) who were admitted for routine pre-surgery or pre-natal blood anal ... | 1994 | 7722542 |
| cytomegalovirus (cmv) and helicobacter pylori (hp) found in oral mucosal ulcers. | the possible involvement of cytomegalovirus (cmv) and helicobacter pylori (hp) in oral mucosal ulcers is suggested by their role in the development of ulceration at other mucosal sites of the gastrointestinal tract. a series of 29 incisional biopsies from 29 consecutive and apparently immunocompetent patients attending the clinic for oral ulceration were examined by routine histopathology as well as by in situ hybridisation (ish) with biotinylated cmv and hp dna probes. in 14/29 biopsies, giemsa ... | 1995 | 7722916 |
| [relationship between molecular typing of helicobacter pylori by pcr-rflp analysis and specificity of disease]. | 1995 | 7723175 | |
| effect of helicobacter pylori eradication on peptic ulcer healing. | in a prospective study designed to assess the effect of helicobacter pylori eradication on peptic ulcer healing, 85 consecutive patients with h. pylori-positive peptic ulcer disease were treated with a triple therapy regimen consisting of colloidal bismuth subcitrate 120 mg four times daily for 28 days, with metronidazole 400 mg three times daily and tetracycline 500 mg three times daily for the first seven days of treatment. h. pylori status was assessed by clo test and histology at least four ... | 1995 | 7724441 |
| peptic ulcer: psychosomatic or infectious disease? etiologic factors revisited ten years after the campylobacter-helicobacter advent. | 1995 | 7724861 | |
| [the drug prophylaxis of peptic ulcer exacerbations]. | 453 patients with ulcer located in the duodenal bulb and pyloric part of the stomach in the presence of helicobacter pylori were examined before and followed up after hospital treatment of the ulcer. the authors findings support the importance of maintenance with current antisecretory drugs and on-demand therapy as well as of combined antibacterial therapy against helicobacter pylori. adequate chemotherapy in the ulcer exacerbation was able to reduce the number of recurrences and complications. | 1995 | 7725253 |
| [stress-induced abdominal pain or helicobacter pylori infection?]. | 1995 | 7725568 | |
| [antibiotic therapy of primary malt stomach lymphomas--have surgery and radiation been replaced?]. | 1995 | 7725760 | |
| relationships between the degree of helicobacter pylori colonisation and the degree and activity of gastritis, surface epithelial degeneration and mucus secretion. | this study investigates the question as to whether, in helicobacter pylori (h.p.) gastritis, any statistically significant relationships are to be found between the following histological parameters: degree of h.p. colonisation, the degree and activity of gastritis, degree of replacement of the foveolar epithelium by regenerating epithelium, and degree of mucus depletion. forceps biopsy material obtained from 240 patients with nud and h.p. gastritis (3 specimens from the antrum, 2 from the corpu ... | 1995 | 7725762 |
| inhibitory action of lansoprazole and its analogs against helicobacter pylori: inhibition of growth is not related to inhibition of urease. | the proton pump inhibitors omeprazole and lansoprazole and its acid-activated derivative ag-2000, which are potent and specific inhibitors of urease of helicobacter pylori (k. nagata, h. satoh, t. iwahi, t. shimoyama, and t. tamura, antimicrob. agents chemother. 37:769-774, 1993), inhibited the growth of h. pylori. the growth was inhibited not only in urease-positive clinical isolates but also in their urease-negative derivatives which had no urease polypeptides. ag-1789, a derivative of lansopr ... | 1995 | 7726537 |
| costs of duodenal ulcer therapy with antibiotics. | intermittent or maintenance therapy with histamine2 antagonists, highly selective vagotomy, or antibiotic therapy to eradicate helicobacter pylori all represent distinct, viable options to manage duodenal ulcer disease. comparing the costs associated with these four approaches could help in deciding among them. | 1995 | 7726700 |
| [is there a relationship between digestive symptoms and h. pylori infection?]. | infection by h. pylori is a common finding in the general population, its prevalence being higher in certain gastroduodenal diseases, particularly peptic ulcer and chronic gastritis. there is no general agreement on whether there is an association between digestive symptoms and the presence of h. pylori infection. | 1995 | 7727174 |
| prevalence of helicobacter pylori infection and gastritis among young adults in china. | to investigate the prevalence of gastritis and h. pylori infection among young chinese in henan province, a high incidence area for oesophageal cancer in china, the gastric mucosa was examined in 194 asymptomatic subjects, aged 15-26 years, in the course of an epidemiological study of precursor lesions of oesophageal cancer. histopathological grading of gastritis and determination of h. pylori infection were performed on haematoxylineosin and warthin-starry stained section. an enzyme-linked immu ... | 1995 | 7728100 |
| "helicobacter heilmannii" infection in a patient with gastric cancer. | 1995 | 7729256 | |
| gastric juice ammonia vs clo test for diagnosis of helicobacter pylori infection. | the aim of the present study was to compare the gastric juice ammonia test to the clo test for the diagnosis of h. pylori infection in culture-proven cases by receiver operating characteristic (roc) curve analysis. we studied 75 subjects (44 with chronic gastritis, 10 with gastric ulcer, 6 with duodenal ulcer, 8 with gastric cancer, and 7 normal) by endoscopy with biopsy for tissue diagnosis, culture of h. pylori. clo test, and by gastric juice ammonia determinations. the culture-positive group ... | 1995 | 7729268 |
| an endoscopic study on relationship between helicobacter pylori infection and endoscopic gastric ulcer scars. | a two-year endoscopic follow-up study of 45 gastric ulcer patients was conducted in order to ascertain the relationship between helicobacter pylori infection, the transformation of ulcer scar patterns, and ulcer relapse during maintenance therapy. endoscopic findings of gastric ulcer scar patterns, which established the quality of ulcer scars, were classified as follows: sa, with a central depression, sb, with a coarse regenerating mucosal pattern up to the center, and sc, with a fine pattern. t ... | 1995 | 7729269 |
| discriminant analysis of factors distinguishing patients with functional dyspepsia from patients with duodenal ulcer. significance of somatization. | patients with duodenal ulcer or functional dyspepsia do not differ on dyspeptic symptoms. the aim of the present study was to test the hypothesis that functional dyspepsia and duodenal ulcer are two different diagnostic entities by examining the discriminating power of several anamnestic, biological, and psychosocial variables. ninety-four patients with duodenal ulcer and 86 patients with functional dyspepsia were included. anamnestic data, global assessment, helicobacter pylori status, blood gr ... | 1995 | 7729272 |
| the importance of local acid production in the distribution of helicobacter felis in the mouse stomach. | helicobacter felis colonizes the gastric mucosa of rodents. preliminary studies showed differences in the distribution of the organism in different parts of the stomach that seemed related to the secretory capacity of the mucosa. the aim of this study was to determine the localization of h. felis in the mouse stomach and to investigate the influence of acid-suppressive agents. | 1995 | 7729630 |
| double-blind trial of omeprazole and amoxicillin to cure helicobacter pylori infection in patients with duodenal ulcers. | anti-helicobacter pylori treatment with combinations of omeprazole and amoxicillin is a promising treatment option. the aim of this study was to investigate whether a daily omeprazole dose of 120 mg combined with amoxicillin would cure h. pylori infection at a rate comparable with that achieved with "triple therapy." | 1995 | 7729633 |
| helicobacter pylori requires an acidic environment to survive in the presence of urea. | the aim of this work was to study the significance of the urease enzyme in promoting helicobacter pylori survival in various environments. a urease-positive h. pylori isolate, strain n6, and an isogenic urease-negative strain, strain n6(ureb::tnkm), were incubated in phosphate-buffered saline at a ph ranging from 2.2 to 7.2 for 60 min at 37 degrees c in both the presence and the absence of 10 mm urea. the number of cfu per milliliter in each solution, the ph of the bacterial supernatant, and the ... | 1995 | 7729871 |
| interleukin-8 response of gastric epithelial cell lines to helicobacter pylori stimulation in vitro. | gastric infection with helicobacter pylori activates a mucosal inflammatory response by mononuclear cells and neutrophils that includes expression of cytokines interleukin-1 beta (il-1 beta), il-6, tumor necrosis factor alpha, and il-8. in this study, we analyzed the il-8 response of human gastric cancer cell lines (kato iii, ags, and mkn28) to h. pylori infection in vitro. il-8 mrna expression was detected by reverse transcription-pcr amplification of rna extracted from epithelial cells after i ... | 1995 | 7729872 |
| stimulation of interleukin-8 production in epithelial cell lines by helicobacter pylori. | following exposure to helicobacter pylori cells, epithelial cell lines secreted interleukin-6 (il-6) and il-8 but not tumor necrosis factor alpha. purified il-6 alone did not stimulate il-8 production from the cell lines tested, indicating that il-6 was not an intermediary in il-8 induction. enhanced il-8 secretion occurred in a time- and dose-dependent manner. none of 12 antibiotics tested exhibited a significant effect on il-8-inducing activity, suggesting that preformed antigens were responsi ... | 1995 | 7729879 |
| additive effect of clarithromycin combined with 14-hydroxy clarithromycin, erythromycin, amoxycillin, metronidazole or omeprazole against helicobacter pylori. | the in-vitro activities of clarithromycin, 14-oh clarithromycin, erythromycin, amoxycillin, metronidazole and omeprazole against helicobacter pylori were determined at ph 7.2 and 5.5. at ph 5.5 the activities of clarithromycin and erythromycin decreased approximately 16 times while 14-oh clarithromycin was less influenced. chequerboard titration indicated that the combined activity of clarithromycin and the other compounds was additive. | 1994 | 7730216 |
| improvement of gastric inflammation and resolution of epithelial damage one year after eradication of helicobacter pylori. | to investigate the effect of eradication of helicobacter pylori infection on gastric epithelial damage and gastritis, scored according to the sydney system. | 1995 | 7730488 |
| drug resistance in helicobacter pylori. | 1995 | 7731077 | |
| helicobacter pylori clearance and eradication with triple therapy in duodenal ulcer patients. | triple therapy was given to 49 chronic helicobacter pylori positive chronic duodenal ulcer cases to see its efficacy in h. pylori clearance, eradication and ulcer healing. h. pylori clearance and eradication rates at week 5 and 8 were 87.8% and 81.5% while ulcer healing rates 68.2% and 81.5% respectively. seven (18%) cases failed to clear h. pylori and were classified as non-responders. histologically 60% showed post-treatment regression of gastritis. tolerance to drugs was excellent with a good ... | 1995 | 7731082 |
| [13c-urea breath test for the detection of helicobacter pylori infection and the assessment of therapeutic effect]. | 1995 | 7731098 | |
| [detection of helicobacter pylori using ota's procedure and mucous immunohistochemistry]. | 1995 | 7731100 | |
| [helicobacter pylori infection as causal factor in the development of carcinoma and lymphoma of the stomach; report who consensus conference]. | 1995 | 7731465 | |
| [cure of a low-grade gastric lymphoma following treatment of helicobacter pylori infection]. | 1995 | 7731470 | |
| [helicobacter pylori in benign gastroduodenal diseases]. | (a light- and electronmicroscopic study). we have examined the occurrence of helicobacter pylori (hp) in 2937 gastric antral biopsy specimens from 979 patients with upper gastrointestinal symptoms. the incidence of hp proved to be 50.5%. the endoscopic diagnoses were: gastritis (62 cases), gastric erosion (425), gastric ulcer (51), duodenitis (22), duodenal erosion (119), duodenal ulcer (122) and the hp incidence was 29, 46, 63,, 50, 66 and 73%, respectively. microscopic findings were: chronic g ... | 1995 | 7731670 |
| [non ulcerative dyspepsia: relationship of symptomatology, gastritis and helicobacter pylori]. | histological alterations of gastric mucosa and its colonization by helicobacter pylori are postuled to be implicated in the pathogenesis of non ulcer dyspepsia. | 1994 | 7732227 |
| association of helicobacter pylori gastric infection with the suppressed thomsen-friedenreich antigen natural humoral response. | a low natural humoral immune response to thomsen-friedenreich antigen (tfa) is a general phenomenon in patients with cancer, including gastric cancer, and in some premalignant conditions. it has been also shown that helicobacter pylori infection is associated with increased risk of gastric cancer. the possible link between the tfa immune response and h. pylori infection was investigated. | 1995 | 7732332 |
| intestinal metaplasia in h. pylori gastritis. | 1995 | 7732343 | |
| what are the real problems for patients with functional dyspepsia? | patients with functional dyspepsia (fd) have more complaints than just the dyspepsia. | 1995 | 7732344 |
| toward an optimal treatment of helicobacter pylori-positive peptic ulcers. | 1995 | 7733070 | |
| impact of colloidal bismuth subnitrate in the eradication rates of helicobacter pylori infection-associated duodenal ulcer using a short treatment regimen with omeprazole and clarithromycin: a randomized study. | recent trials have shown that duodenal ulcers treated by h2-blockers heal faster if helicobacter pylori is eradicated concurrently. | 1995 | 7733075 |
| double pylorus: report of a longitudinal follow-up in two refractory cases with underlying diseases. | double pylorus is either a congenital abnormality or an acquired complication of peptic ulcer disease. we had followed two patients for 3 and 5 yr, respectively, to observe the processes of formation and the prognosis of double pylorus. initially, duodenal ulcer was found in one patient with diabetes mellitus and chronic renal failure, and gastric ulcer was found in the other with chronic obstructive pulmonary disease. both developed double pylorus with refractory courses. in spite of intensive ... | 1995 | 7733094 |
| [kuhn's paradigms and helicobacter pylori: disencounters]. | 1995 | 7734713 | |
| adhesion to and invasion of hela cells by helicobacter pylori. | eight clinical isolates and two reference strains of helicobacter pylori were studied with regard to their interactions with hela cells. all the isolates adhered poorly to hela cells and the number of invasive bacteria was very low. no correlation was found between the adherence and invasiveness of the isolates on one hand, and the corresponding patients having ulcer or non-ulcer disease, or the ability of the strains to produce cytotoxin and to induce an oxidative burst of human polymorphonucle ... | 1995 | 7734829 |
| metronidazole susceptibility testing of helicobacter pylori with the pdm epsilometer test (e test). | the bacteriostatic activity of metronidazole against helicobacter pylori was determined with the pdm epsilometer test (e test) and with an agar dilution test. both methods correlated in the minimum inhibitory concentration (mic) ranges (< or = 0.5- > 32 mg/l) and in the mic 50 (e test: 1 mg/l; agar dilution test: 2 mg/l) and mic 90 (> 32 mg/l) values. however, comparison of test results of single strains revealed that 14 out of 105 strains (13.3%) were classified as resistant by one method but c ... | 1995 | 7734833 |
| helicobacter pylori infection in children with recurrent abdominal pain. | helicobacter pylori was cultured and helicobacter-like organisms (hlo) were seen in 6 (16%) of 37 children with recurrent abdominal pain. five children had concomitant histological inflammation, but none had endoscopic changes. all 6 children demonstrated positive serology. compared with the total group, they were more often from developing countries, larger families and lower social groups. treatment with phenoxymethyl penicillin and colloidal bismuth subcitrate did not result in side effects o ... | 1994 | 7734870 |
| mechanisms of gastric mucosal damage. | 1994 | 7735047 | |
| gastric epithelial cell proliferation. | 1994 | 7735048 | |
| the diagnosis of helicobacter pylori in gastric preneoplastic and neoplastic lesions. | 1994 | 7735049 | |
| helicobacter pylori: the portuguese scene. grupo de estudo portugues do helicobacter pylori (gephp). | 1994 | 7735050 | |
| the prevalence of helicobacter pylori infection in patients with intestinal metaplasia and in controls: a serological and histological study in four united kingdom centres. the uk sub-group, the ecp-euronut intestinal metaplasia study group. | 1994 | 7735051 | |
| the frequency of helicobacter pylori associated peptic ulcer disease and of autoimmune-associated conditions in gastric and renal cancer: a retrospective comparison in 267 patients. | 1994 | 7735052 | |
| the ecp-im intervention study. | 1994 | 7735056 | |
| role of helicobacter pylori in gastric carcinoma. | helicobacter pylori infection has recently been incriminated in the pathogenesis of gastric carcinoma and chronic atrophic gastritis and intestinal metaplasia are considered to be precursors of this condition. although the incidence of helicobacter pylori infection in india is high that of gastric carcinoma is low. we, therefore, decided to examine the association between helicobacter pylori, intestinal metaplasia and gastric carcinoma in a prospective study. | 1995 | 7735060 |
| 6th international symposium on helicobacter pylori and its diseases. tokyo, japan, 16-17 september 1993. | 1994 | 7735922 | |
| helicobacter pylori infection in japan: current status and future options. | the combination of the high prevalence of helicobacter pylori infection in japan and the availability of methods to diagnose and treat the infection suggest that elimination of the infection from the population might be beneficial. therefore we reviewed the epidemiology, consequences and possible benefits of elimination of h. pylori in japan. | 1994 | 7735923 |
| pharmacological effects of metronidazole+tetracycline+bismuth subcitrate versus omeprazole+amoxycillin+bismuth subcitrate in helicobacter pylori-related gastritis and peptic ulcer disease. | two 4-week triple-therapy treatment regimens, metronidazole+tetracycline+bismuth subcitrate and omeprazole+amoxycillin+bismuth subcitrate, were compared in a randomly allocated double-blind trial for their efficacy in eradicating helicobacter pylori from the gastric mucosa of patients with gastritis and/or peptic ulcer disease. | 1994 | 7735924 |
| non-steroidal anti-inflammatory drugs associated with gastroduodenal injury and helicobacter pylori. | to clarify the relationship between non-steroidal anti-inflammatory drug (nsaid)-associated gastroduodenal mucosal injury and helicobacter pylori infection. | 1994 | 7735925 |
| are there ulcerogenic strains of helicobacter pylori? | aim: to outline the evidence for and against ulcerogenic strains of helicobacter pylori. controversy: although h. pylori is now well established as a predisposing factor in peptic ulcer disease the question of why only a minority of people infected with h. pylori develop peptic ulceration remains unanswered and is the subject of much controversy. common view: perhaps the most accepted view to date is the belief that there are ulcerogenic strains of h. pylori which produce a specific cytotoxin re ... | 1994 | 7735926 |
| eradication of helicobacter pylori. | to critically review current indications and therapies for helicobacter pylori eradication. | 1994 | 7735927 |
| effects of anti-ulcer agents on antibiotic activity against helicobacter pylori. | to investigate the mechanism of action of a series of potential combination therapies for use against helicobacter pylori. | 1994 | 7735928 |
| combination therapy with clarithromycin and sofalcone for eradication of helicobacter pylori. | to clarify the efficacy of combination therapy with clarithromycin and sofalcone for eradication of helicobacter pylori. | 1994 | 7735929 |
| characteristics of vacuolating toxin produced by helicobacter pylori. | we sought a good indicator cell line to use in detecting the vacuolating toxin produced by helicobacter pylori and in examining the characteristics of the toxin. | 1994 | 7735930 |
| vacuolating cytotoxin production by helicobacter pylori isolates from peptic ulcer, atrophic gastritis and gastric carcinoma patients. | we investigated the production of vacuolating cytotoxin by helicobacter pylori isolates from patients with peptic ulcer, atrophic gastritis or gastric carcinoma in order to examine the pathophysiological significance of vacuolating cytotoxin in these diseases. | 1994 | 7735931 |
| mucosal interleukin-8 and helicobacter pylori-associated gastroduodenal disease. | to review the role of interleukin (il)-8 in the immunopathology of helicobacter pylori-associated gastroduodenal disease. | 1994 | 7735932 |
| effects of cytotoxic factors of helicobacter pylori on superoxide generation in situ in the rabbit stomach. | to evaluate the effect of certain cytotoxic products of helicobacter pylori on superoxide generation in situ and on the infiltration by polymorphonuclear cells into the gastric mucosa. the agents studied were ammonia, a culture supernatant of h. pylori, and n-formyl-methionyl-leucyl-phenylalanine (fmlp), a chemotactic factor. | 1994 | 7735933 |
| effect of gastric mucosal blood flow on the pathogenesis of ammonia in helicobacter pylori-induced gastric mucosal injury. | we investigated the effects of the gastric mucosal blood flow on the pathophysiology of ammonia-induced gastric mucosal damage. | 1994 | 7735934 |
| essential role of helicobacter pylori urease in gastric colonization: definite proof using a urease-negative mutant constructed by gene replacement. | to investigate the involvement of urease in helicobacter pylori colonization in the nude mouse stomach by using a genetically defined urease-negative mutant. | 1994 | 7735935 |
| toxic factors of helicobacter pylori. | to review the various toxic factors produced directly or indirectly by helicobacter pylori and discuss their relative importance in h. pylori infection. | 1994 | 7735936 |
| genetic heterogeneity of helicobacter pylori by pulse-field gel electrophoresis and re-evaluation of dna homology. | the genetic heterogeneity of helicobacter pylori isolates was re-evaluated by using pulse-field gel electrophoresis to examine macrorestriction patterns and by studying dna homology. | 1994 | 7735937 |
| gastric disease in ferrets: effects of helicobacter mustelae, nitrosamines and reconstructive gastric surgery. | animal models are being used to study the mechanisms by which helicobacter spp. induce gastric disease. to assess the effects of a natural gastric pathogen, helicobacter mustelae, in the development of chronic gastritis, premalignancy and cancer, the ferret model was studied under natural and experimental conditions. | 1994 | 7735938 |
| the use of a mouse model in the study of helicobacter sp.-associated gastric cancer. | hypothesis: long-term infection with helicobacter pylori and the associated gastritis is now thought to cause a predisposition to gastric cancer through cellular changes resulting from inflammatory damage or because of direct effects of the bacterium. mice as models for h. pylori-associated gastric cancer: long-term infection of conventional swiss mice with either h. felis or h. heilmannii results in atrophic gastritis. infection of specific pathogen-free balb/c mice results in the development o ... | 1994 | 7735939 |
| establishment of an animal model for chronic gastritis with helicobacter pylori: potential model for long-term observations. | to assess the suitability of an established experimental model for chronic gastritis associated with helicobacter pylori for use in long-term observations. | 1994 | 7735940 |
| intestinal metaplasia, atrophic gastritis and stomach cancer: trends over time. | the pathogenetic association of chronic atrophic gastritis and intestinal metaplasia with gastric cancer implies that the trends seen in these disorders over time should be similar. both should similarly decrease in incidence with time, and a time-related relationship should occur between the incidence of gastric cancer and the rate of development of atrophic gastritis in the stomach of helicobacter pylori-infected subjects. | 1994 | 7735941 |
| relationship between helicobacter pylori and atrophic gastritis. | to investigate the relationship between helicobacter pylori and atrophic gastritis. | 1994 | 7735942 |
| the effect of the immune response to helicobacter pylori in the development of intestinal metaplasia. | to determine whether cytotoxic helicobacter pylori antibodies occur in gastric mucosa, and whether these antibodies contribute to the development of intestinal metaplasia. | 1994 | 7735943 |
| helicobacter pylori infection in gastric carcinoma. | this study was undertaken to compare the pathoclinical findings in gastric adenocarcinoma with serum igg antibody to helicobacter pylori. | 1994 | 7735944 |
| current status of helicobacter pylori in peptic ulcer disease. | all patients with documented, past or present gastric or duodenal ulcers and who are infected with helicobacter pylori should undergo antimicrobial therapy to eradicate it. data do not yet support giving antimicrobial therapy to treat nonulcer dyspepsia or to prevent gastric neoplasia. h pylori infection is the main cause of chronic superficial gastritis and is associated with both gastric and duodenal ulcers. however, it has no proven relationship with nonulcer dyspepsia. h pylori infection is ... | 1995 | 7736634 |
| genome dna analysis and genotyping of clinical isolates of helicobacter pylori. | the genotype of genome dna from seventeen clinical isolates of helicobacter pylori by pulsed-field gel electrophoresis (pfge) and arbitrarily primed polymerase chain reaction (ap-pcr) was determined. three restriction enzymes, apa i, kpn i and not i, were found to produce distributions of dna fragments which were useful for analysis of the chromosome-sized dna from h. pylori nctc11637t by pfge. many of the isolates of h. pylori could not be genotyped by pfge after digestion reaction with apa i, ... | 1994 | 7736770 |
| a substantial proportion of non-ulcer dyspepsia patients have the same abnormality of acid secretion as duodenal ulcer patients. | acid secretion in response to gastrin releasing peptide (grp) is increased six-fold in helicobacter pylori positive duodenal ulcer (du) patients and threefold in h pylori positive healthy volunteers, and this fully resolves after eradication of the infection. this study was undertaken to determine whether a proportion of h pylori positive patients with non-ulcer dyspepsia (nud) have an acid secretion disturbance similar to du patients. basal and grp stimulated gastrin concentrations and acid out ... | 1995 | 7737559 |
| effect of helicobacter pylori status on intragastric ph during treatment with omeprazole. | to test the hypothesis that helicobacter pylori infection is associated with a decreased intragastric acidity during omeprazole therapy, ambulatory 24 hour dual point gastric ph recordings were performed in 18 h pylori positive and 14 h pylori negative subjects. there was a four to six week washout period between the two ph recordings made in each subject after one week courses of placebo or omeprazole, 20 mg daily. during placebo, median 24 hour ph values were not different in the corpus (h pyl ... | 1995 | 7737560 |
| helicobacter pylori eradication in the african setting, with special reference to reinfection and duodenal ulcer recurrence. | the aim of this study was to determine the effect of helicobacter pylori eradication on the natural history of duodenal ulcer disease, and to determine the incidence of reinfection in adult patients where h pylori had been eradicated in a community with a high prevalence of the infection. an investigator blinded study, with 24 month endoscopic follow up, in subjects where h pylori had been eradicated, and similarly treated subjects where it had not been eradicated was conducted at a tertiary ref ... | 1995 | 7737561 |
| [what is the connection between helicobacter pylori and dyspepsia?]. | 1995 | 7737618 | |
| [diagnosis of gastrointestinal infections]. | 1995 | 7737805 | |
| helicobacter pylori infection, serum pepsinogen level and gastric cancer: a case-control study in japan. | we conducted a case-control study to evaluate the effect of helicobacter pylori (hp) infection on the risk of gastric cancer in tokyo, japan. the sera at the time of diagnosis from 282 gastric cancer cases and 767 sex- and age-matched cancer-free controls were tested for the presence of anti-hp igg antibody (hm-cap elisa kit) and serum pepsinogen (pg) level (pg i and pg ii riabead). no significant association was observed in all sets [matched odds ratio (or) = 1.04, 95% confidence interval: 0.73 ... | 1995 | 7737912 |
| in-vitro hepatotoxic factor in helicobacter hepaticus, h. pylori and other helicobacter species. | several inbred strains of mice in closed breeding colonies were found to have spiral-shaped bacteria associated with active, chronic hepatitis. a new species of helicobacter, h. hepaticus, was isolated from the infected livers of some strains of mice. other strains of mice were colonised with h. hepaticus in the caecum and colon, but not the liver. filtersterilised supernatant fluid from five strains of h. hepaticus was tested in a mouse liver cell line (atcc no. ccl 9.1) for cytotoxic activity. ... | 1995 | 7739025 |
| [newly developed detection system for serum helicobacter pylori antibodies using elisa and its clinical significance]. | using elisa, a specific and sensitive system that detects serum immunoglobulin g antibodies against all soluble antigens of helicobacter pylori (hp) has been developed. this system is used at three different concentrations of hp antigens coated on the solid phase of the elisa. anti-hp antibodies were judged positive when the difference in the elisa values between high and middle or middle and low concentrations of antigen were over the specific values. for the elisa system, called the three poin ... | 1995 | 7739119 |
| [clinical and etiological studies of igg antibodies to helicobacter pylori detected by enzyme-linked immunosorbent assay]. | recently, helicobacter pylori (h. pylori) has been reported that it is involved in the pathogenesis of duodenal ulcer and might be a risk factor for gastric cancer. to diagnose h. pylori infection, detection of serum antibody is much less stressful and more cost effective than gastric biopsy. using a serological method, we have reported that the prevalence of serum anti-h. pylori igg was elevated with age among healthy subjects and over 80% among elder people. thus, it would be essential to inve ... | 1995 | 7739120 |
| helicobacter pylori infection and the risk for duodenal and gastric ulceration. | to determine whether a preexisting helicobacter pylori infection increases the risk for developing duodenal or gastric ulcer. | 1994 | 7741826 |
| genetic abnormalities during transition from helicobacter-pylori-associated gastritis to low-grade maltoma. | 1995 | 7741894 | |
| [the effect of "triple therapy" on the eradicating of h. pylori and the healing of a duodenal ulcer. the initial study and 6 months later]. | helicobacter pylori plays an important role in the pathogenesis of peptic ulcer disease, and many therapy regimens have been used to eradicate it. | 1995 | 7742047 |