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limitations in the use of 14c-glycocholate breath and stool bile acid determinations in patients with chronic diarrhea.analysis of a modified 14c-glycocholate breath test on 165 consecutive in-patients being investigated for chronic diarrhea showed that the measurement of 14co2 between 3 and 6 h after oral dosing of 5 microci of 14c-glycocholic acid was of only limited use to distinguish between patients with crohn's disease (cd), idiopathic bile salt wastage (ibw), or ileal resection (ir) from those with the irritable bowel syndrome (ibs). continuing 14co2 collections for up to 24 h was of little more help in e ...20113090133
annual summary 1984. reported morbidity and mortality in the united states. 20113092006
ontogenetic development of pancreatic thyrotropin-releasing hormone in human foetuses and in infants.the ontogeny of thyrotropin-releasing hormone (trh) in pancreata of human foetuses from 15-36 weeks of gestation and of infants has been studied. trh was detectable in the pancreas of a 15 week old foetus; a progressive increase of pancreatic trh content was observed until the 34th week of gestation, whereas a progressive decrease was found in the late period of pregnancy and in 1 year old infants. in contrast, the pancreatic insulin content showed a progressive increase during the entire pregna ...19863092527
effect of aldose reductase inhibitor (sorbinil) on integration of polyol pathway, pentose phosphate pathway, and glycolytic route in diabetic rat lens.this study examines the effect of an aldose reductase inhibitor (sorbinil) on the flux of specifically labeled glucose through alternative pathways of metabolism in the lens of normal and diabetic rats 1 wk after the induction of diabetes with alloxan. in the diabetic rat lens, there was an apparent increase in the flux of glucose through the pentose phosphate pathway (ppp), as measured by the difference in the yields of 14co2 from [1-14c]glucose and [6-14c]glucose [c1-c6], this value was 0.087 ...19863093302
discordant effects of prednisone on anticardiolipin antibodies and the lupus anticoagulant. 20113094545
purification and partial characterization of a vibrio hollisae hemolysin that relates to the thermostable direct hemolysin of vibrio parahaemolyticus.hemolysin produced by vibrio hollisae (vh-rtdh), which is related to the thermostable direct hemolysin (vp-tdh) of vibrio parahaemolyticus, was studied. vh-rtdh was purified by successive column chromatographies on diethylaminoethyl-cellulose and an immunoaffinity column coupled with anti vp-tdh immunoglobulin. the purified toxin was homogeneous, as demonstrated by conventional and sodium dodecyl sulfate--polyacrylamide gel electrophoresis (page). the molecular weight of vh-rtdh was slightly sma ...19863094925
metastatic melanoma to the epididymis suspected on preoperative ultrasound. 20103095399
evaluation of a bacteriological screening method for drinking water control on board ships. 20113095683
intracellular distribution of 73,000 and 72,000 dalton heat shock proteins in hela cells.intracellular localization of 73,000 and 72,000 dalton heat shock proteins (hsp73/72) in hela cells that were heat shocked or treated with chemical stressors was investigated using indirect immunofluorescent staining. the antiserum used specifically recognized the hsp73/72 in hela cells, and hsps were increased by heating cells at 42 degrees c for 2 or 4 h and by prior treatment with chemical stressors (sodium arsenite, cadmium chloride, 8-hydroxyquinoline and ethanol). there was diffuse cytopla ...19863098874
thromboxane a2 biosynthesis in human disease.thromboxane a2 (txa2), the predominant cyclooxygenase product of human platelets, is a potent vasoconstrictor and platelet agonist. although its biological properties are readily appreciable in vitro, it has been difficult to define its biological importance in vivo. to a large extent this reflected the problems associated with efforts to monitor biosynthesis of this eicosanoid and the lack of selective pharmacological probes that prevented the synthesis of txa2 or antagonized its biological act ...19873100340
induction of phage-like particles from a pathogenic strain of vibrio parahaemolyticus by mitomycin c.a rapid drop of absorbance of cell suspensions due to cell lysis was observed midway in cell growth of a pathogenic strain, vibrio parahaemolyticus wp1, when the cells were incubated in a growth medium containing mitomycin c. we succeeded in isolating phage-like particles from the cell lysate, but not from that of the non-pathogenic strain, wp28. the purified particle has a clear-cut envelope and is hexagonal in shape with no tail. the size of particles is about 65 millimicrons on the diagonal a ...19863101681
evidence for neoplastic cell differentiation in mediastinal t lymphoblastic lymphoma.immunostaining of frozen sections from a mediastinal t lymphoblastic lymphoma (t-ll) revealed the existence of two neoplastic cell populations characterized by different degrees of maturation. several large nodules of 3a1+/t11+/t9+ t6-/t4-/t8-/t3- lymphoid cells, resembling normal early thymocytes, were surrounded by 3a1+/t11+/t9+/t6+/t4+/t8+/t3- cells resembling normal cortical thymocytes. the junctional area between early and cortical lymphocytes was occupied by numerous leu-m3+/pam-1+/dr+ ret ...19873103325
lessons from a nursing home. 20113103447
characterization of impermeability variants of pseudomonas aeruginosa isolated during unsuccessful therapy of experimental endocarditis.we characterized five amikacin-resistant variants of pseudomonas aeruginosa isolated from aortic valve vegetations during unsuccessful therapy of experimental endocarditis. these organisms were cross resistant to other aminoglycosides. no aminoglycoside-modifying enzymes were produced by these strains. however, all five variants demonstrated significant defects in permeability and intracellular uptake of [3h]amikacin when compared with the amikacin-susceptible parental strain (0 to 26% of that o ...19873105442
characterization of impermeability variants of pseudomonas aeruginosa isolated during unsuccessful therapy of experimental endocarditis.we characterized five amikacin-resistant variants of pseudomonas aeruginosa isolated from aortic valve vegetations during unsuccessful therapy of experimental endocarditis. these organisms were cross resistant to other aminoglycosides. no aminoglycoside-modifying enzymes were produced by these strains. however, all five variants demonstrated significant defects in permeability and intracellular uptake of [3h]amikacin when compared with the amikacin-susceptible parental strain (0 to 26% of that o ...19873105442
salt tolerance of lactose-grown vibrio parahaemolyticus carrying escherichia coli lac genes.lac- strains of vibrio parahaemolyticus were converted to lac+ on receiving a hybrid plasmid containing the lactose utilization genes of escherichia coli k-12. a v. parahaemolyticus strain containing this hybrid plasmid exhibited optimal growth rates on glucose and other carbon sources in the presence of 0.2 to 0.4 m nacl. growth of the same strain on lactose was inhibited at similar concentrations of nacl. the altered growth rate responses in lactose medium appeared to be attributable to effect ...19873105458
[antimicrobial susceptibility of vibrio parahaemolyticus and vibrio alginolyticus isolated from human feces and foods]. 19873106535
saliva lithium monitoring in prepubertal children. 20113108230
biosynthesis and processing of platelet gpiib-iiia in human megakaryocytes.platelet membrane glycoprotein iib-iiia forms a calcium-dependent heterodimer and constitutes the fibrinogen receptor on stimulated platelets. gpiib is a two-chain protein containing disulfide-linked alpha and beta subunits. gpiiia is a single chain protein. these proteins are synthesized in the bone marrow by megakaryocytes, but the study of their synthesis has been hampered by the difficulty in obtaining enriched population of megakaryocytes in large numbers. to examine the biosynthesis and pr ...19873108266
differences between saccharomyces cerevisiae and bacillus subtilis in secretion of human lysozyme.saccharomyces cerevisiae secreted human lysozyme in the medium as an active form when the signal peptides of chicken lysozyme and a chicken lysozyme-aspergillus awamori glucoamylase hybrid were used, whereas it did not synthesize any human lysozyme protein by using the signal peptide of a. awamori glucoamylase. the secreted lysozyme was easily purified and crystallized. on the other hand, bacillus subtilis secreted an inactive human lysozyme, which seemed to have incorrect disulfide bonds, with ...19873109419
caloric requirements in total parenteral nutrition.resting energy expenditure (ree) was measured in 100 consecutive total parenteral nutrition (tpn) patients. only forty-eight percent of the measured rees were within 90-110% of the predicted harris-benedict values. a literature review revealed 191 published guidelines for non-protein caloric requirements of hospitalized tpn patients. these guidelines were appropriately matched and applied to the 100 individual tpn patients. the relationship between the recommended caloric supply and measured cal ...20113110244
stimulation by hyphopichia burtonii and bacillus amyloliquefaciens of aflatoxin production by aspergillus flavus in irradiated maize and rice grains.aspergillus flavus was grown on maize and rice extract agars and on irradiated viable cracked maize and rice grains, either in pure culture or in dual culture with wild strains of either hyphopichia burtonii or bacillus amyloliquefaciens. aflatoxin production by a. flavus and its growth and interactions with the other microorganisms were studied at three water activities (aw) (0.98, 0.95, and 0.90) and two temperatures (25 and 16 degrees c). both h. burtonii and b. amyloliquefaciens markedly sti ...19873111368
lower oesophageal contractility as an indicator of brain death in paralysed and mechanically ventilated patients with head injury. 20113111608
expression of genes in cloned murine cell lines that can be maintained in both interleukin 2- and interleukin 3-dependent growth states.two cloned murine cell lines, fd.c/1 and 32dcl-23 exhibit switching of lymphokine-dependent growth states. the bone marrow-derived fd.c/1 and 32dcl-23 cell lines are normally grown in culture medium supplemented with interleukin 3 (il3). the replacement of il3 with interleukin 2 (il2) in the medium results in an increase in il2 receptor expression in fd.c/1 and 32dcl-23 cells and the switching of cells to an il2-dependent growth state. we have compared patterns of protein and phosphoprotein synt ...20113111985
[drug-resistance and transferable r plasmids in vibrio cholerae o-1 and non o-1, v. fluvialis and v. parahaemolyticus recently isolated from human sources]. 19873112272
reliability of road accident statistics. 20113112385
oesophageal pain exacerbated by propranolol. 20113113570
distribution of indicator bacteria and vibrio parahaemolyticus in sewage-polluted intertidal sediments.the impact of a sewage point source on the bacterial densities in an intertidal mud flat in boston harbor, mass., was investigated. the area, savin hill cove, acts as a receiving basin for a combined storm and sewage outlet (cso). preliminary examination of sediments and overlying water at high tide demonstrated that fecal coliforms were present in sediments at abundances 2 to 4 orders of magnitude higher than in the overlying water column. the following bacterial counts were determined from sed ...19873116932
refractive surgery. 20113120886
deficiency of eosinophil peroxidase detected by automated cytochemistry. 20113122494
purification and characterization of a hemolysin produced by a clinical isolate of kanagawa phenomenon-negative vibrio parahaemolyticus and related to the thermostable direct hemolysin.a clinical isolate (strain 4037) of kanagawa phenomenon-negative vibrio parahaemolyticus was studied. although the strain was judged to be kanagawa phenomenon-negative by various conventional tests, it produced a new hemolysin (named vp-trh, for thermostable direct hemolysin [vp-tdh]-related hemolysin) that was related to the vp-tdh produced by ordinary kanagawa phenomenon-positive v. parahaemolyticus. vp-trh was purified by ammonium sulfate fractionation and successive column chromatographies o ...19883126151
modification of arachidonic metabolism by flavonoids.the pharmacological effects of many plants depend on their flavonoid constituents. this review is concerned with the influence of flavonoids on arachidonic metabolism as the possible mechanism of action of such natural products. special attention has been paid to structure-activity relationships since this knowledge may allow the synthesis of more potent and selective analogs with therapeutic applications.20113126368
decreased locomotor activity produced by repeated, but not single, administration of murine-recombinant interferon-gamma in mice.a single treatment with murine-recombinant interferon-gamma (murifn-gamma; 30 micrograms/mouse), whether evaluated immediately after, or four hrs after, intraperitoneal injection, does not alter open field activity levels. on the other hand, repeated murifn-gamma administration (30 micrograms/mouse/day for 5 days) results in decreased spontaneous locomotor activity and an increase in body weight.19883126371
a triple amputation. 20113126419
quality assurance in ambulatory health care. 20113126476
[vibrio parahaemolyticus infectious disease caused by kanagawa phenomenon-negative o3:k6 originated from maldives]. 19873127502
[enterostoma therapy--a pilot course in the essen education center of the german nursing association]. 20113127632
implications of drug levels in body fluids: basic concepts.drug concentrations in biological fluids are affected by the dose, route of administration, pattern of drug use, and the dispositional kinetics (distribution, metabolism, and excretion) of the drug. as most drugs are distributed to the site of action by blood, drug concentration measurement in this body fluid provides the best information as to the potential effect on behavior such as driving impairment or on psychological high. due to wide individual variations in the pharmacokinetics and pharm ...20113127724
[use of the o-nitrophenyl-beta-d-galactopyranoside test in the rapid diagnosis of strains of enterobacteria]. 20113130711
high progesterone/estradiol ratio in follicular fluid at oocyte aspiration for in vitro fertilization as a predictor of possible pregnancy.eighteen women undergoing in vitro fertilization (ivf) procedures were studied. all had optimal (900 to 1600 pg/ml) peak serum estradiol (e2) response to the same stimulation regimen with clomiphene citrate and menotropins; fertilization rate was above 64%; and two to four embryos in two to eight cell stages were replaced in each patient. all were considered to have optimal chances for conception. the authors compared progesterone (p), e2, and p/e2 ratio in serum and follicular fluid (ff) at the ...20113131157
records involving riders of powered two-wheeled vehicles. 20113131520
valproate-associated hepatotoxicity and its biochemical mechanisms.intake of the anticonvulsant drug valproic acid, or its sodium salt, has been associated with occasional instances of severe and sometimes fatal hepatotoxicity. probably at least 80 cases have occurred worldwide. the syndrome affects perhaps 1 in 10,000 persons taking the drug, and usually develops in the early weeks or months of therapy. most instances have involved children, usually those receiving more than 1 anticonvulsant. multiple cases have occurred in 2 families. the typical presentation ...20113131628
surgical aspects of drug smuggling. 20113133033
departmental divisions and the crisis in undergraduate medical education. 20113133048
risk of upper respiratory tract infection and malaria prophylaxis. 20113133070
serum albumin adducts in the molecular epidemiology of aflatoxin carcinogenesis: correlation with aflatoxin b1 intake and urinary excretion of aflatoxin m1.aflatoxin-serum albumin adducts in the blood of 42 residents of guangxi province, people's republic of china, were determined and compared with intake of aflatoxin b1 (afb1) and excretion of aflatoxin m1 (afm1) in urine. blood specimens were obtained during the same period that urine was collected and that diet was sampled. serum albumin was isolated from blood by affinity chromatography on reactive blue 2-sepharose and subjected to enzymatic proteolysis using pronase. immunoreactive products we ...19883133131
prostacyclin biosynthesis and phospholipase activity in hypoxic rat myocardium.phospholipid metabolism was studied in rat myocardial slices that were incubated under normoxia or hypoxia for up to 24 hours. phospholipid degradation was prominent in hypoxic myocardium, particularly phosphatidylcholine, which markedly decreased after 24 hours of hypoxia. in contrast, lysophosphatidylcholine increased. the mechanism of phospholipid degradation in hypoxic myocardium was studied. the highest activity for phospholipase a2 among subcellular fractions was found in microsomal fracti ...19883133132
bone mineral metabolism in experimental diabetes mellitus: osteocalcin as a measure of bone remodeling.the etiology of diabetic osteopenia has not been established. the value of serum osteocalcin (bgp) as a marker of the bone abnormalities and the possible role of the polyol pathway in diabetic osteopenia were investigated. three groups of rats were studied over 7 weeks: group d (n = 12), rats with streptozotocin (55 mg/kg)-induced diabetes given saline by gavage; group ds (n = 12), rats with streptozotocin-induced diabetes given the aldose reductase inhibitor sorbinil (25 mg/kg) daily by gavage; ...19883133194
on the diagnostic significance of cft in respiratory-syncytial virus infection in children over one year old. 19873133290
biosynthesis of porphyrins and left ventricle function in patients with terminal renal insufficiency. 20113133291
industry weighs merits of long-term care bills. 20113133303
evaluation of eight and a half years of neonatal screening for haemoglobinopathies in birmingham.a pilot neonatal screening programme for haemoglobinopathies linked with screening for phenylketonuria and congenital hypothyroidism was reviewed. during 1978 to december 1986 137,000 neonates were tested. there were improvements in the detection rate and accuracy of diagnosis for homozygotes and mixed heterozygotes, mainly associated with the introduction of citrate agarose gel electrophoresis as a follow up procedure on all specimens showing any abnormality on the initial cellulose acetate ele ...20103135019
segregation analysis of juvenile myoclonic epilepsy.we examined the inheritance of juvenile myoclonic epilepsy (jme). we looked at both the trait of "epilepsy" and the trait of "epilepsy-plus-eeg abnormalities," since eeg abnormalities are frequently found in the clinically unaffected sibs of jme patients. we tested several modes of inheritance including the fully penetrant recessive and several two-locus models. we could reject all models tested (fully penetrant single-locus and two-locus models) when abnormal eegs were classified as "unaffected ...20103136050
hiv seroprevalence in migrant and seasonal farmworkers--north carolina, 1987. 19883136308
vibrio parahemolyticus-associated diarrhea in spain. 19883137059
development of a highly sensitive bead-elisa to detect bacterial protein toxins.a highly sensitive sandwich enzyme-linked immunosorbent assay to detect bacterial toxins was developed. fab' of anti-toxin igg was conjugated with horseradish peroxidase by the maleimide method and tetramethylbenzidine was used as substrate. as the solid phase, a 6.5 mm diameter polystyrene bead was used and this was coated with the anti-toxin igg. the entire assay could be completed within 3.5 hr. the sensitivity of this bead-elisa was found to be quite high with various bacterial toxins: less ...19883143897
pseudoanaphylaxis: two case studies. 20113143943
poor lifestyle modification among intravenous drug users assisted at a sexually transmitted disease clinic for hiv infection diagnosis, madrid, 1987. 19883146273
imperforate anus in 700,000 consecutive liveborn infants.we have studied the incidence of imperforate anus (anorectal atresia and stenosis) occurring in almost 700,000 consecutive liveborn infants in british columbia (b.c.) from 1964-1982 using the records of a health surveillance registry which uses multiple sources of ascertainment. the estimated incidence rate was 1 in 2,524 live births (273 cases out of 689,118 consecutive liveborn infants). data pertaining to sex ratio, additional anomalies, recurrence, and mortality were also analyzed over the p ...20113146285
prevention of respiratory distress syndrome.rds continues to be a major problem for premature infants despite a better understanding of its pathophysiology and of ways to try to prevent it. to date, prenatal administration of glucocorticoids has been the most widely used method of accelerating fetal lung development. however, several limitations of this therapy have prompted the search for alternative approaches. most efforts have focused on the potential use of combined hormonal therapy with glucocorticoids and either thyroid hormones or ...19883146813
possible interactions between zolpidem, a new sleep inducer and chlorpromazine, a phenothiazine neuroleptic.the combined use of a hypnotic and a neuroleptic is a rather frequent situation, encountered especially in the psychiatric sphere. we therefore tested zolpidem and chlorpromazine in six healthy subjects by using a double-blind latin square design. all of them received single doses of 20 mg zolpidem (zol), 50 mg chlorpromazine (cpz) and the combination of zol + cpz. the medication was given as a single dose in the morning and each treatment being separated by a 1-week interval. zolpidem produced ...20113147477
withdrawal of barbiturate anticonvulsant drugs: prospective controlled study.a barbiturate (phenobarbital or primidone) was withdrawn over a period of 3 months from 25 institutionalized residents, all of whom had had three seizures or less in the past 6 months and were maintained on a nonsedating drug (phenytoin, carbamazepine, or valproic acid). results were compared with a matched comparison group maintained on both drugs. subjects withdrawn from primidone, but not those withdrawn from phenobarbital, had increased seizure frequency, probably due to withdrawal. after 14 ...20113147687
isolation of the early phase of chylomicron formation in intestinal epithelial cells of rats.lipid is first observed electron microscopically in the rough endoplasmic reticulum of intestinal epithelial cells during active lipid absorption. we have been able to isolate this subcellular fraction by using discontinuous sucrose gradients of 0.25/0.86/1.11 m sucrose. a preliminary low speed centrifugation of mucosal homogenate removed the heavier subcellular organelles. the resulting supernatant was centrifuged at 5.25 x 10(6) x g.min. the pellet from this centrifugation was placed on top of ...19883147719
[effects of intracerebroventricularly injected cholecystokinin octapeptide on the electric activities of pain-reacted neurons in nucleus parafascicularis of thalamus in rats]. 19883151154
[esophageal diseases in the elderly]. 20103152439
the iridovirus frog virus 3: a model for trans-acting proteins.the amphibian iridovirus, frog virus 3 (fv3), produces at least two trans-activating proteins that stimulate the expression of viral genes. one of these proteins induces transcription from the promoter of an immediate-early fv3 gene, whereas the other induces transcription from exogenously methylated dna. these proteins may serve as a model for both viral and cellular trans-acting factors.19863153144
anti-idiotypic antibodies: a new generation of vaccines against infectious agents.anti-idiotypic antibodies have been suggested recently as candidates for potential vaccines against numerous infectious organisms. these antibody-based vaccines might represent a new generation of vaccines for inducing protective immunity in susceptible hosts.20103153167
acute leukemia with extramedullary presentation and mixed myeloid and lymphoid expression. 20103153242
effects of acetyl strophanthidin on duration of atrial fibrillation in the neurally-intact and blockaded dog.although the inotropic and dromotropic effects of cardiac glycosides in atrial fibrillation (af) are well recognized, their action on af itself is not clear. accordingly, to determine whether cardiac glycosides prolong af, the duration of electrically induced af, atrioventricular conduction, and left ventricular function were assessed for 30 minutes before and for 30 minutes following intravenous administration of acetyl strophanthidin (as), 20 micrograms/kg, in neurally intact, beta-blocked, an ...19883154634
non-immune igg f(ab')2 binding to group c and g streptococci is mediated by structures on gamma chains.the present investigation was designed to determine whether the heavy or the light immunoglobulin chain is involved in the non-immune binding of igg f(ab')2 fragments to specific surface receptors on human group c and g streptococci. purified human polyclonal igg was mildly reduced with dithiothreitol and alkylated with iodoacetamide. light (l) and heavy (h) chains were separated. intact igg and purified l and h chains of polyclonal immunoglobulin g were tested in an inhibition assay for non-imm ...19853156400
divalent cation-dependent atpase activities in ciliary membranes and other surface structures in paramecium tetraurelia: comparative in vitro studies.cilia membrane preparations from axenically grown paramecium contain atpase activities with distinct electrophoretic mobilities on triton-polyacrylamide gels [m.j. doughty and e.s. kaneshiro (1983) j. protozool. 30, 569-575]. such gel analyses also show additional atpase activity bands associated with ciliary axonemes (dyneins), cell pellicles, exocytotic trichocysts, and the external cell surface (ectoenzyme). in the present report, the in vitro properties of these activities in various cell fr ...20113157347
direct selection of mutations reducing transcription or translation of the reca gene of escherichia coli with a reca-lacz protein fusion.when a reca-lacz protein fusion was cloned into phage lambda, the resulting transducing phage grew normally on wild-type escherichia coli, but its growth was severely inhibited in lexa(def) mutant strains that express reca constitutively at high levels. mutants of the transducing phage that grew on the lexa(def) strains were isolated and were found to affect production of the reca-beta-galactosidase hybrid protein. most mutants, including a number of nonsense mutants, were phenotypically lacz-. ...19853160689
structural and functional studies of the effects of sympathetic nerve stimulation on rabbit submandibular salivary glands.continuous sympathetic stimulation at 8-10 hz caused intense vasoconstriction in the gland, so stimulation was generally given in an interrupted pattern to minimize this detrimental effect on secretion. only a small increase in fluid secretion occurred; it became thick and tended to block the cannula; therefore in later experiments the main duct was not cannulated. after sympathetic stimulation there was substantial degranulation of acinar cells. however, as this was accompanied by little moveme ...19883165262
an investigation into the relative sealing ability of five commercially used temporary restorative materials. 20113165335
cleavage lines of the oral mucosa in japanese cadavers.cleavage lines were experimentally reproduced in the oral mucosa of japanese cadavers. they were investigated macroscopically and histologically. the reproduced cleavage lines showed little directional variation by sex or age. from the histological findings, the mucosal cleavage lines were interpreted to represent cleavage split along the direction of connective tissue fibres in the lamina propria.20113165386
a peculiar complication in le fort i osteotomy.in two cases of routine le fort i osteotomy in secondary cleft palate surgery, a swelling noted in the antral mucosa was biopsied. in both cases, histological examination resulted in a diagnosis of odontogenic myxoma. after analysis of the radiographs, it was concluded that the biopsies were taken from displaced tooth germs. the close histological similarity between myxoma on the one hand and dental papilla tissue, a thickened tooth follicle and a thickened or polypoid antral mucosal lining on t ...20113165391
[pharmacokinetics of cefmenoxime in renal-failure patients undergoing continuous arteriovenous hemofiltration].we investigated the pharmacokinetics of cefmenoxime (cmx) administrated to renal-failure patients undergoing continuous arteriovenous hemofiltration (cavh). cavh was carried out with a filter (0.5 m2) employing a pan-50p (hollow fiber type) made of polyacrylonitrile membrane, with a blood flow rate of 100 ml/min and a filtration rate of 1,200 ml/hr. at 5 and 300 minutes after the cmx administration, the concentrations of cmx in the serum were 126.8 mg/l and 31.5 mg/l, respectively. the t1/2 beta ...20113165473
[cavity lining for composite restorations: critical estimate]. 20113166150
[epidemiology of blindness in the bouche-du-rhône area. methodological approach]. 20113168117
characterization of muscarinic receptor subtypes on human peripheral lung.to better define the role of muscarinic receptors in lung responses and airway diseases, we characterized the binding of the m1-specific antagonist, [3h]pirenzepine (pz), and the nonspecific (m1- and m2-) antagonist, [3h]quinuclidinyl benzilate (qnb), to human peripheral lung tissue. data obtained from 15 different lung specimens showed that the radioligands bound to single high-affinity sites with dissociation constant (kd) values ranging from 1 to 9 nm for [3h]pz and 0.03 to 0.46 nm for [3h]qn ...19883170410
metastatic adenocarcinoma of the carpus: a case report.a patient is described who presented with a painful swelling of the dorsum of the hand which arose from the hamate and proved histologically to be a secondary from a previously resected gastric adenocarcinoma.20113171299
survival of vibrio parahaemolyticus in two gastropod molluscs, clithon retropictus and nerita albicilla. 19883172602
[dynamics of sexuality and sex customs]. 20113173040
haemolytic-uraemic syndrome after treatment with metronidazole.this paper describes the clinical features of six children who developed the haemolytic-uraemic syndrome after treatment with metronidazole. these children were older and were more likely to have undergone recent bowel surgery than are other children with this condition. while the involvement of metronidazole in the aetiology of the haemolytic-uraemic syndrome is not established firmly, the action of this drug in sensitizing tissues to oxidation injury and the reported evidence of oxidation chan ...20113173180
jurisprudent obstetrics. 20113176291
isolation from a coastal fish of vibrio hollisae capable of producing a hemolysin similar to the thermostable direct hemolysin of vibrio parahaemolyticus.a vibrio isolated from the intestine of a coastal fish was identified as vibrio hollisae by its biochemical characteristics. the isolate reacted with the gene probe for the thermostable direct hemolysin of vibrio parahaemolyticus. the hemolysin produced by the isolate from the fish had traits identical to those of the thermostable direct hemolysin-like hemolysin produced by a clinical strain of v. hollisae.19883178217
community based health care in the philippine highlands: the hanunuo mangyans of mindoro. 20113179104
epidemiology of htlv-i in gabon (western equatorial africa).in 1986 a survey to determine the distribution of htlv-i infection was conducted in gabon in a representative sample of adults and children. five samples were taken in adults and 2 samples in children living in urban and rural areas. samples were taken by the cluster sampling technique, i.e., clusters of randomly selected households. sera were tested for igg antibodies to htlv-i by elisa. elisa-positive sera were retested by western blot. the study comprised 1,874 adults and 684 children, all ap ...20113182104
temporal relationship of vibrio parahaemolyticus in patients and the environment.we prospectively compared the occurrence of vibrio parahaemolyticus in patients and the environment in the pacific northwest. inpatient and outpatient stool and wound specimens and water samples from 10 estuarine sites were cultured for v. parahaemolyticus over a period of 3 years. v. parahaemolyticus infections were detected in 13 patients (8 with gastroenteritis; 5 with wound infections), and all of the infections were found in outpatients in physicians' offices. ten of the infections were loc ...19883183022
the 'holy plane' of rectal surgery. 20113184105
criteria that discriminate between native proteins and incorrectly folded models.various theoretical concepts, such as free energy potentials, electrostatic interaction potentials, atomic packing, solvent-exposed surface, and surface charge distribution, were tested for their ability to discriminate between native proteins and misfolded protein models. misfolded models were constructed by introducing incorrect side chains onto polypeptide backbones: side chains of the alpha-helical hemerythrin were modeled on the beta-sheeted backbone of immunoglobulin vl domain, whereas tho ...20083186690
sodium butyrate increases glucose transporter expression in llc-pk1 cells.the effect of sodium butyrate on the expression of the facilitated glucose transporter (gt) was investigated in the pig kidney cell line llc-pk1. when cells were treated with butyrate, gt mrna expression was remarkably enhanced with a maximal effect at 5 mm. levels of gt mrna were increased at 1 day after butyrate treatment and continued to increase for at least 4 days; however, acetate and propionate did not affect gt mrna levels significantly. the induction of gt mrna by butyrate was accompani ...19883186708
hepatotoxicity of cyclophosphamide in man: pharmacokinetic analysis.of 44 patients with neoplasia treated with cyclophosphamide (cpa), 19 (43%) had a transient elevation of serum levels of aminotransferases. in these patients, regardless of the combination chemotherapy regimen given, the incidence of liver dysfunction was 33%, when the total cpa dose was less than 400 mg/m2 (group a) and 73% with higher doses (group b). prior to the initiation of cpa treatment, pharmacokinetics of cpa were investigated in 15 patients. plasma aucs of cpa and phosphoramide mustard ...19883187190
helping the deaf in kenya. 20113187393
differential modulation of host cell and hiv gene expression by combinations of avarol and azt in vitro.human immunodeficiency virus type 1 (hiv-1) gene expression is modulated by some virus-encoded proteins, possibly acting at multiple levels of control, which are also known to be involved in the regulation of gene expression in uninfected cells (transcriptional, post-transcriptional, nucleocytoplasmic transport, and translational control). two anti-hiv-1 drugs, avarol and 3'-azido-3'-deoxythymidine, which inhibit viral replication by differential mechanisms, were used to study the role of cytopl ...19883190740
chicken liver basic fatty acid-binding protein (pi = 9.0). purification, crystallization and preliminary x-ray data.chicken liver basic fatty acid-binding protein (pi = 9.0) has been purified with a high yield by a modification of a method originally applied to rat liver. the final product is highly homogeneous and can be used to grow crystals that belong to two different space groups. the crystals are either tetragonal, space group p4(2)2(1)2 with a = b = 60.2 a and c = 138.1 a or orthorhombic, space group p2(1)2(1)2(1) with a = 60.7 a, b = 40.1 a and c = 66.7 a. the second form appears to be more suitable f ...19883191992
poona district leprosy committee annual report for 1985-86. 20113192982
activities and properties of putrescine-biosynthetic enzymes in vibrio parahaemolyticus.the biosynthetic pathways for putrescine (put) in vibrio parahaemolyticus were delineated by measuring activities of the enzymes which would be involved in its biosynthesis. experiments with labeled arginine and ornithine revealed that both of these amino acids were converted into put by intact cells. the activities of three enzymes, arginine decarboxylase (adc), ornithine decarboxylase (odc), and agmatine ureohydrolase (auh), were detected in cell extracts. adc and odc of v. parahaemolyticus we ...19883193911
the disposition of [2,3-14c]-methyl and [2,3-14c]-2-ethylhexyl acrylate in male wistar albino rats.the disposition of methyl [2,3-14c]-acrylate (ma) and 2-ethylhexyl [2,3-14c]-acrylate (eha) following intraperitoneal and oral administration to rats has been studied. the 14c found in the tissues was mainly associated with liver, kidneys and lungs. loss of 14c from these tissues occurred fairly rapidly, excluding the rats given eha intraperitoneally. most of the administered acrylates underwent rapid metabolism and excretion with expired air (more than 50% of the dose and urine (10-50% of the d ...19883196152
[accidental inversion of the gastroscope in the esophagus]. 20113197612
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