Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| [urogenital tuberculosis in antituberculosis dispensary practice]. | the investigations carried out within the district depending upon the dispensary showed that urogenital tuberculosis incidence is in the second place, after respiratory tuberculosis; in 47% of the cases it was the only manifestation of the disease, in the other cases it was secondary to or accompanied other tuberculous localizations. | 1996 | 174176 |
| receptor-mediated control of cholesterol metabolism. | 1996 | 174194 | |
| [etiologic role of cytomegalovirus in infectious mononucleosis and certain viral diseases]. | 1975 | 174231 | |
| interaction of ultrasound with neoplastic tissue. ii. systemic effects after local sonic irradiation. | local sonic irradiation was applied to subcutaneously implanted furth-columbia rat wilms' tumor. the weight and the rate of tritiated thymidine uptake were measured in host organs distal to the application field. kidney and spleen weights were inhibited by the wilms' tumor, and sonication of the tumor removed all or part of this inhibition. liver weight was increased after sonication of tumor-bearing rats but not in nontumor-bearing rats. this may have been a response to tumor-specific substance ... | 1976 | 174264 |
| association of herpes simplex virus type 1 dna with host chromosomal dna during productive infection. | 1976 | 174293 | |
| [electron microscopy of malignant synovialoma]. | 1996 | 174333 | |
| the nasal fundus ectasia. | the object of this work has been to describe an eye anomaly consisting of a series of individual characteristics. as a name for the disorder "the nasal fundus ectasia" has been selected. special attention has been paid to the bitemporal visual field defects which can easily lead to a suspicion of tumour in the region of the optic chiasm. | 1996 | 174383 |
| metabolism of thymine in tumor tissue: the origins of beta-aminoisobutyric acid. | 1975 | 174403 | |
| rheumatology rounds at the hospital for special surgery. aspects of systemic lupus erythematosus: consideration of viral and genetic factors, and remarks on therapy. | the presentation of sle in one member of a twin pair has provided the background for discussion of genetic and environmental variables involved in the pathogenesis of the syndrome. there are promising leads (developing in parallel with studies in man and in nzb mice) suggesting that sle results from the interaction of genetic factors with an etiologic stimulus provided by type-c rna viruses. the principles of management of sle have been reviewed briefly. | 1975 | 174427 |
| accumulation of some secretory enzymes in venom glands of vipera palaestinae. | secretion of venom in the venom glands of vipera palaestinae was studied by measuring the protein content and enzymatic activities of l-amino acid oxidase (lao), phosphodiesterase (pde), and benzoylarginine ethyl esterase (baee). these were tested in the accumulating venom and gland homogenates at 0, 2, 3, 4,6, and 15 days after an intitial emptying of the venom glands by milking. changes in the total activities of the enzymes and in the protein concentration were found in the venom samples, but ... | 1996 | 174447 |
| [biopsy and morphology]. | 1996 | 174513 | |
| galactose metabolism in relation to cataract formation in marsupials. | erythrocytic galactokinase and/or galactose-1-phosphate uridyl transferase activity were low in many species of marsupials. however, cataract formation was observed only in pouch-young members of these species when reared on cow's milk. the galactose tolerance of young kangaroos was found to be greatly impaired, but improved rapidly and markedly at the stage of which the definitive structure of the ruminant type of stomach as in adults is formed. the combination of high absorption of galactose a ... | 1975 | 174538 |
| murine leukaemia virus expression in the akr following thymectomy. | thymectomy effectively prevents the development of spontaneous lymphoma in the akr but how this effect is achieved remains to be determined. one possible mechanism, namely suppression of genomic expression of the oncogenic murine leukaemia virus now seems unlikely since levels of the group specific mulv antigen were in comparision with their sham operated controls unaltered in both neonatally and adult thymectomized akr. | 1975 | 174705 |
| increased cyclic adenosine 3',5'-monophosphate content in guinea pig ileum after exposure to staphylococcus aureus delta-toxin. | to compare staphylococcus aureus delta-toxin with cholera toxin, which is known to increase cellular cyclic adenosine 3',5'-monophosphate (camp), studies were undertaken to determine the effect of delta-toxin on the camp content of guinea pig ileum maintained in vitro. concentrations of delta-toxin as low as 0.40 mug/ml increased camp levels in guinea pig ileum after 2 h of incubation. histological damage was seen in ileum exposed for 2 h to delta-toxin concentrations of 100 mug/ml. as little as ... | 1976 | 175015 |
| immunological properties of bovine serum lipoproteins and chemical analysis of their protein moieties. | four classes of bovine serum lipoproteins were isolated by precipitation with dextran sulfate, ultracentrifugation, and preparative electrophoresis on polyacrylamide gel. very low density lipoprotein (d less than 1.019 g/ml) was related immunologically to low density lipoprotein-two (d 1.039 to 1.060 g/ml) and high density lipoprotein (d 1.060 to 1.210 g/ml) was related immunologically to low density lipoprotein-one (d 1.019 to 1.039 g/ml), but the two pairs were immunologically distinct. the ma ... | 1976 | 175102 |
| poisonous snakebite: a review. 2. symptomatology and treatment. | 1997 | 175130 | |
| parathyroid function tests with edta infusions in infancy and childhood. | to determine the functional capabilities of the parathyroid glands, 17 edta infusions were given to 11 children (ages 1 month to 12 years) and to two mothers of four of the children. serum ionized ca fell from 4.1 mg/dl to 3.4 mg/dl. excessive parathyroid hormone responses were elicited during seven of nine edta infusions in five children and in one adult with hypophosphatemic rickets, during the active phase of rickets. in four of five subjects with problems related to hypercalcemia, borderline ... | 1997 | 175144 |
| ultrastructure of mycoplasma-like organisms purified from clover phyllody-affected plants. | 1976 | 175171 | |
| translation of oncogenic virus rna in xenopus laevis oocytes. | 1976 | 175294 | |
| clinical applications of cell surface markers. | 1975 | 175398 | |
| dependence of myocardial redox systems on the concentration of exogenous substrate. | isolated rat hearts were perfused according to langendorff at a range of perfusion pressures and the variations of intracellular oxygenation were studied under these conditions by optical methods. the oxygen consumption was directly related to left ventricular performance in all cases examined, the relationship being independent of both the substrate used (glucose, beta-oh-butyrate) and its concentration (2.5, 5.0, 10.0 mm). the changes in the respiratory rate were accompanied by modifications o ... | 1975 | 175412 |
| [the current state of masculine contraception]. | the present state of male contraception is reviewed with reference to pharmacological methods only. since spermatogenesis is the result of a long chain of endocrine mechanisms starting in the hypothalamus, any review of contraceptive techniques must follow these physiological links. spermatogenesis itself involves different stages and each of them can be a target for pharmacological compounds. although no drug is currently available that offers all the necessary guarantees required of a contrace ... | 1997 | 175439 |
| behaviorally evoked hippocampal theta waves: a cholinergic response. | forced running in a treadmill results in the instantaneous appearance of a synchronous electroencephalographic pattern in the dorsal hippocampus of the rat. a similar bioelectric response in the absence of movement is induced by physostigmine. both responses are blocked with scopolamine. lesions of the medial septal nucleus abolish hippocampal theta waves induced by forced running or physostigmine. | 1975 | 175440 |
| [leukocytosis and polynucleosis in infectious disease]. | during bacterial infections, the intensity of the polymorphonuclear leukocytosis depends on the bacterium but also on the mechanism and extent of the infection. polymorphonuclear leukocytosis is greater during pyogenic and anaerobic infections. it is due to deep suppuration, septicemia of thrombophlebitic origin, acute endocarditis, purulent meningitis and pneumonia. the increase in the number of polymorphonuclear cells is, on the other hand, less marked in sub-acute bacterial endocarditis. apar ... | 1975 | 175454 |
| [association of behçet's disease and pelvispondylitis in a subject without hla w 27 antigen]. | the authors report a new case of behcet's disease in association with ankylosing spondylitis. a study of the hla system in this patient, showed the presence of an hla 5 (behcet's disease) and the absence of hla w 27 (ankylosing spondylitis). the authors recall the frequency of hla w 27 during ankylosing spondylitis, whether primary or associated with psoriasis, or enteric disease. desensitisation to autologous saliva proved a failure. a trial of d-penicillamine produced no beneficial effect on t ... | 1997 | 175493 |
| pancytopenia and "caillary leak syndrome" with infectious mononucleosis. | a 19-year-old man with documented infectious mononucleosis presented with pancytopenia and a megaloblastic bone marrow. he developed a "capillary leak syndrome" with an expanded plasma volume of 9,290 ml and normal right heart and pulmonary artery pressures. the patient had a dramatic recovery after corticosteroid therapy. | 1976 | 175508 |
| estrogen binding and estrogen receptors in the prostate. | 1997 | 175521 | |
| [dermatofollicular method of vaccination of chickens against newcastle disease and pox]. | 1975 | 175550 | |
| villous adenomas of the colorectum. | during a ten-year period 258 patients with villous adenomas were seen at the massachusetts general hospital: seventy-four of these patients (29%) had invasive cancer that developed in adenomas. the operative mortality ascribed to removal of benign adenomas was zero, but for cancer arising in villous adenomas it was 3 per cent. therapy often is difficult because of the size and location of the tumors. methods of removal have been considered in detail. | 1997 | 175719 |
| effects of cholera enterotoxin, glucagon, and dibutyryl cyclic amp on rat liver alkaline phosphatase, bile flow, and bile composition. | cholera enterotoxin, 45 mug per 250 g body weight, administered intravenously to rats, caused a 6-fold rise in the activity of liver alkaline phosphatase in 12 hr. there was no change in bile volume or in the concentration or total bile content of na+, k+, hco3-, or cl- for 36 hr after the administration of cholera toxin. however, bile phospholipid output fell markedly from a control level of 15.0 +/- 1.0 mumol per 6 hr to a low level of 4.0 +/- 1.2 mumol per 6 hr in the 12- to 18-hr collection, ... | 1976 | 176082 |
| immune host response to corneal grafts sensitized to herpes simplex virus. | experiments were performed to study the fate of corneal grafts sensitized to herpes antigens when grafted to hsv-sensitized hosts. nonsensitized grafts in systemically sensitized hosts remained clear, whereas all locally sensitized grafts in systemically sensitized hosts became opaque within ten days. the stroma showed severe lymphocytic and plasma cell infiltration and neovascularization. one-half of the corneas from systemically sensitized hosts grafted to eyes previously infected opacified in ... | 1976 | 176129 |
| activation of adenylate cyclase by cholera toxin in rat liver homogenates. | the effect of cholera toxin on adenylate cyclase from rat liver has been studied in a broken cell preparation. the activation of the enzyme in this in vitro preparation requires the addition of nicotinamide adenine dinucleotide (nad) to the incubation medium and the presence of cell components other than the membrane-bound adenylate cyclase. once the activation of the cyclase is produced, the effect persists despite repeated washing or solubilization of the enzyme. the effect can be obtained wit ... | 1976 | 176181 |
| mechanism of activation adenylate cyclase in vitro by polymyxin-released, heat-labile enterotoxin of escherichia coli. | heat-labile enterotoxic material released from escherichia coli by polymyxin b activates the adenylate cyclase of pigeon erythrocyte ghosts in a time- and concentration-dependent manner. the activation requires nicotinamide adenine dinucleotide, adenosine triphosphate, and another component of the erythrocyte supernatant. the active species has a molecular weight of about 23,000-24,000 daltons, is inhibited by antibodies to the toxin of vibrio cholerae, and is not irreversibly denatured by sodiu ... | 1976 | 176279 |
| mode of action of vibrio cholerae enterotoxin in cultured adrenal tumor cells. | the effects of vibrio cholerae enterotoxin on steroidogenesis and on formation of adenosine 3':5'-cyclic phosphate (cyclic amp) in two adrenal tumor cell lines were compared. steroidogenesis was half-maximal at concentrations of 1 ng of cholera toxin/ml in the mutant os-3 cells and 3 ng of cholera toxin/ml in the parent y-1 cells. at the end of an 8-hr incubation, toxin-induced formation of cyclic amp in the mutant cell line was reduced by 90%. a molar ratio of gm1 ganglioside (galactosyl-n-acet ... | 1976 | 176280 |
| multiple roles of erythrocyte supernatant in the activation of adenylate cyclase by vibrio cholerae toxin in vitro. | peptide a1 of vibrio cholerae toxin, nicotinamide adenine dinucleotide, adenosine triphosphate, and a soluble protein present in erythrocyte supernatant are required for the activation of pigeon erythrocyte ghost adenylate cyclase but are not required to maintain the activated state. the compounds are all required simultaneously, and when all are added to ghosts, adenylate cyclase activity increases at a linear rate without delay. under optimal conditions significant activation of cyclase is giv ... | 1976 | 176281 |
| cholera toxin and the adenylate cyclase-activating signal. | studies with chemically modified cholera toxin derivatives showed that all treatments that decreased the ability of toxin to bind to mouse thymus cells or to polystyrene-coupled gm1 ganglioside caused a concomitant reduction in the toxin's ability to increase adenosine 3':5'-cyclic phosphate (cyclic amp) in thymus cells and skin vascular permeability in rabbits. dissociation of the h (heavy) and l (light) subunits abolished the biologic activity without inhibiting receptor binding, as did treatm ... | 1976 | 176282 |
| interaction of vibrio cholerae toxin with sarcoma 180 cell membranes. | three discrete phases are discernible in the activation, by vibrio cholerae toxin, of adenylate cyclase in fragments of sarcoma 180 cell membranes. in the first, or preparatory, phase the toxin must be exposed to dithiothreitol or nicotinamide adenine dinucleotide (nad) in the absence of the membranes. in the second phase, the prepared toxin is dissociated to yield a macromolecular cyclase-activating factor (mcaf) in the presence of the membranes. in the third phase, membrane basal adenylate cyc ... | 1976 | 176283 |
| orphan airlift. enteric pathogens isolated from vietnamese children immigrating to the united states. | isolation studies for bacterial and parasitic agents were carried out on stool specimens from vietnamese infants at the time of their mass airlift to the united states. one or more bacterial pathogens were found in 49% of the 367 stool specimens cultured. the isolates included enteropathogenic escherichia coli (161), shigella (16), salmonella (15), but no salmonella typhi or vibrio cholerae. parasites identified in 88 stool specimens included giardia lamblia (10), ascaris lumbricoides (7), and e ... | 1976 | 176481 |
| inhibition of enterotoxin-induced intestinal secretion by the polypeptide antibiotic, polymyxin. | 1976 | 176498 | |
| structure and function of cholera toxin and hormone receptors. | the enterotoxin from vibrio cholerae is a protein of 100,000 mol wt which stimulates adenylate cyclase activity ubiquitously. the binding of biologically active 125i-labeled choleragen to cell membranes is of extraordinary affinity and specificity. the binding may be restricted to membrane-bound ganglioside gm1. this ganglioside can be inserted into membranes from exogenous sources, and the increased toxin binding in such cells can be reflected by an increased sensitivity to the biological effec ... | 1976 | 176537 |
| [the effect of multiple injections of acth (alone and combined with sodium ribonucleinate) on incorporation of p32-orthophosphate into the mitochondrial rna of the liver, spleen and heart of white rats]. | 1976 | 176651 | |
| [effect of cyclic amp on the proliferation and differentiation of hematopoietic cells (literature survey)]. | 1975 | 176654 | |
| zollinger-ellison syndrome. | 1995 | 176667 | |
| a chemical approach for the localization of membrane sites involved in lymphocyte activation. | 1995 | 177007 | |
| cofactor recycling in liquid membrane-enzyme systems. | 1995 | 177010 | |
| positive inotropic activity of cholera enterotoxin on the embryonic chick heart. | the characteristics of the positive inotropic effect of different preparations of cholera toxin on the isolated 4-day-old embryonic chick heart were investigated. crude (cct) as well as partially purified and purified (pct)preparations of cholera toxin were shown to have positive inotropic activity. contractility was increased within 1 minute and reached a maximum at approximately 40 minutes after exposure to toxin. activities of all three toxin preparations were abolished by heating, their effe ... | 1976 | 177757 |
| barriers to research in psychiatric-mental health nursing: implications for preparing the nurse researcher. | 1996 | 177768 | |
| psychophysiological reactions as a function of life stress and behavioral rigidity. | studies have shown that vulnerability to disease is a function of psychosocial factors. this study hypothesized that disease onset is antedated by life changes and is influenced by the individual's "behavioral rigidity." the subjects were 160 female college students from three undergraduate general elective courses. an index of life change (lci) was administered to each subject, presenting descriptions of important pressures and conflicts, with instruction that she indicate which ones she had pe ... | 1996 | 177772 |
| functional incorporation of ganglioside into intact cells: induction of choleragen responsiveness. | nctc 2071 cells are unable to synthesize the monosialoganglioside gm1. when grown in chemically defined medium these cells contained no detectable gm1 and did not accumulate 3': 5'-cyclic amp in response to choleragen. incubation of the cells with [3h]gm1 permitted quantification of ganglioside uptake which was dependent on time and concentration of [3h]gm1 in the medium. responsiveness to choleragen was demonstrated with binding of as few as 17,000 molecules of [3h]gm1 per cell; a maximal respo ... | 1976 | 177969 |
| pregnancy interrupting effects of some bacterial toxins. | embryotoxic properties of shigella dysenteriae and clostridium perfringens toxins, of e. coli endotoxin, v. cholerase and e. coli enterotoxins were compared in mice. e. coli endotoxin has embryotoxic effects at all stages of pregnancy. e. coli enterotoxin v. cholerae enterotoxin and shigella dysenteriae toxin are most effective mainly at earlier stages of pregnancy. clostridium perfringens toxin has no embryotoxic effect. | 1976 | 178014 |
| ovarian tumours in childhood: a 27-year review. | twenty-five children treated for ovarian neoplasms at the royal hospital for sick children, yorkhill,glasgow, between 1947 and 1974 are reported. eight of the patients had malignant tumours and 17 benign. the patients with benign tumours were treated by either salpingo-oophorectomy or oophorectomy. the malignant cases were treated with either surgery alone or in combination with deep x-ray therapy and/or chemotherapy. two patients died of malignant teratoma, but the remaining 6 with malignant te ... | 1996 | 178398 |
| monolayer cultures of normal adult rat adrenocortical cells: steroidogenic responses to nucleotides, bacterial toxins and antimicrotubular agents. | monolayer cultures of normal rat adrenocortical cells were treated with agents which stimulate steroidogenesis by y-1 adrenal tumour cells. choleragen was active, whereas cyclic nucleotides other than cyclic amp, bacterial endotoxins and antimicrotubular agents were inactive. | 1976 | 178525 |
| activation of intestinal mucosal adenylate cyclase by shigella dysenteriae i enterotoxin. | because the mechanism whereby shigella dysenteriae i enterotoxin induces intestinal secretion is unclear, the effect of this toxin on adenylate cyclase activity in rabbit ileal mucosa was studied under various in vitro and in vivo conditions. activation of adenylate cyclase by shigella enterotoxin was observed only when substrate (atp) concentrations above the km of adenylate cyclase were employed. these concentrations of atp are greater than those required to demonstrate activation of adenylate ... | 1976 | 178569 |
| pregnenolone, 17-oh-pregnenolone, and testosterone in plasma of patients with congenital adrenal hyperplasia. | both pregnenolone and 17-oh-pregnenolone were found to be higher in the plasma of patients with poorly controlled congential adrenal hyperplasia than in normal subjects. the plasma levels of these precursor steroids were significantly correlated with urinary 17-ketosteroid and pregnanetriol excretion and with plasma testosterone. the mechanism where by plasma pregnenolone and 17-oh-pregnenolone levels are elevated in patients with 21-hydroxylase deficiency is unknown, but the phenomenon of produ ... | 1997 | 178685 |
| oppositional effects of acetylcholine and isoproterenol on isometric tension and cyclic nucleotide concentrations in rabbit atria. | the effects of acetylcholine chloride and isoproterenol on myocardiial cyclic gmp, cyclic amp and on isometric tension were studied in isolated electrically driven rabbit atria. acetylcholine (0.5 mum) produced a significant decrease in isometric force that was associated with a significant elevation in atrial cyclic gmp. cyclic amp was significantly lowered at 15 seconds after the addition of acetylcholine, but was only slightly decreased at earlier time periods. both the negative inotropic act ... | 1975 | 178695 |
| rhinovirus multistranded rna: dependence of the replicative form on the presence of actinomycin d. | the multistranded and double-stranded rnas synthesized in hela cells infected with rhinovirus in the presence and in the absence of actinomycin d have been characterized by polyacrylamide gel electrophoresis and hybridization studies. the replicative form is only found in infected cells treated with actinomycin d, whereas the replicative intermediate is found in both the presence and the absence of the drug. the significance of these results is discussed. | 1997 | 178930 |
| [symptomatology of diseases caused by c1. perfringens]. | 1976 | 178949 | |
| [prevention of relapse in the era of depot neuroleptics and social psychiatry]. | 1997 | 179025 | |
| [antibodies to viral antigens in rheumatoid arthritis]. | 1976 | 179153 | |
| viral diseases of cats: current concepts. | 1976 | 179185 | |
| [localization of genome rna synthesis in sendai virus]. | localization of sendai virus 50s rna in ehrlich ascitic carcinoma cells was studied. at 48 hours postinfection virus-specific 50s rna was found in the nucleus after 30 min exposure to 3h-uridine, and its amount increased after 1-hour exposure to the precursor reaching 18% of the total nucleus virus-specific rna. after 2-hour or longer exposure to the precursor the amount of 50s rna in the nuclei decreased considerably and in the cytoplasm in this gradient region a considerable radioactivity appe ... | 1975 | 179216 |
| [health aspects of the study of bdellovibrio bacteriovorus as a natural factor in the self-purification of reservoirs]. | 1975 | 179245 | |
| [the biological role of estriol]. | it was demonstrated on the uteri of women and guinea pigs that estriol (in vitro) possessed a marked affinity to the estradiol-binding system of human and guinea pig uteri; the activity of steroid-receptor interaction of estriol in vitro constituted 9.4% for guinea pigs and 17% for man in relation to the estradiol activity. administration of estriol to guinea pigs in vivo in a dose of 0.25-0.5 mg led to a sharp reduction of the estradiol-binding capacity of the receptor system of the uterus. it ... | 1975 | 179639 |
| [the diuretic action of morphine in rats]. | 1976 | 179647 | |
| [role of bioenergetic changes in the mechanism of action of nonsteroid anti-inflammatory agents]. | in experiments on rats the antiphlogistic action of sodium mephenaminate and salicylate was found to be more pronounced under conditions of ovalbumin than that of dextran inflammation. the antiphlogistic effect of sodium salicylate was greater than that of mephenaminate in ovalbumin inflammation; this correlated with a more marked drop in the content of lactic acid in the blood and with a more complete elimination of uncoupling of oxidative phosphorylation in the hepatic mitochondria than in cas ... | 1976 | 179649 |
| arginyl-trna synthetase from baker's yeast. purification and some properties. | arginyl-trna synthetase from baker's yeast (saccharomyces cerevisiae, strain 836) was obtained pure by a large-scale preparative method, which involves four chromatographic columns and one preparative polyacrylamide gel electrophoretic step. the enzyme has a high specific activity (9000 u/mg) and consists of a single polypeptide chain of molecular weight approximately 73000 as determined by polyacrylamide gel electrophoresis in the presence of sodium dodecylsulphate. amino acid analysis of the e ... | 1976 | 179818 |
| biochemical and mechanical effects of phenylephrine on the heart. | injections of phenylephrine into isolated perfused guinea pig hearts increased cyclic amp and phosphorylase a. reserpine pretreatment or propranolol decreased or abolished the phenylephrine-induced biochemical changes without affecting the contractile response. phentolamine, on the other hand, shifted the phenylephrine dose-response curve for contractility to the right without affecting the other parameters. the biochemical effects of phenylephrine are apparently due to the release of noradrenal ... | 1976 | 179825 |
| studies on the adduct of 4-phenyl-1,2,4-triazoline-3,5-dione with vitamin d3. | 1985 | 180271 | |
| [radioreceptor assay of gonadotropin]. | 1976 | 180307 | |
| sodium-stimulated alpha-aminoisobutyric acid transport by membrane vesicles from simian virus-transformed mouse cells. | uptake of alpha-aminoisobutyric acid, by membrane vesicles derived principally from the plasma membrane and endoplasmic reticulum of mouse 3t3 cells transformed by simian virus 40, is stimulated by sodium chloride. both in the presence and absence of na+ uptake is time-dependent and osmotically sensitive. the na+-stimulated uptake is inhibited by other amino acids. the kinetics of transport of alpha-aminoisobutyric acid are shown to be biphasic both in whole cells and in the membrane vesicles. o ... | 1976 | 180527 |
| inhibition of avian sarcoma virus replication by glucosamine: a specific effect on the synthesis and processing of viral proteins. | 2003 | 180659 | |
| [studies on the physiopathology of cholera in bari]. | during a small epidemic of cholera in south italy in summer of 1973, the infection showed some peculiarities and differences in comparison with cholera classic picture of asiatic areas. in this paper epidemiological, pathogenetic, clinical and biochemical data of patients admitted to the institute of infectious diseases of bari are reported. the age of the majority of patients (over 50) is an important factor for understanding cause of infection; but also preexistent basal diseases are responsib ... | 1975 | 180912 |
| nitrogenase of azotobacter chroococcum. kinetics of the reduction of oxidized iron-protein by sodium dithionite. | the kinetics of the reduction of oxidized fe-protein of nitrogenase from azotobacter chroococcum by sodium dithionite were studied by stopped-flow and rapid-freezing e.p.r. (electron-paramagnetic-resonance) spectroscopy. the appearance of the gav. = 1.94 e.p.r. signal (0.24 electron integrated intensity/mol) was associated with a one-electron reduction by so2--with k greater than 10(8)m-1-s-1 at 23 degrees c. a value of k = 1.75s-1 was obtained for the rate of dissociation of s2o42- into 2so2-- ... | 1976 | 180978 |
| endonucleolytic cleavage of murine leukemia virus 35s rna by microsome-associated nuclease. | 1976 | 180996 | |
| arthroscopic findings of the knee in patients with pseudogout. | 2003 | 181011 | |
| pseudogout: clinical observations and chemical analyses of deposits. | 2003 | 181012 | |
| phosphorylation of the active, a1 component of cholera toxin by protein kinase. | cholera toxin, an activator of adenylate cyclase in a wide variety of cells, is a substrate for the phosphotransferase reaction catalyzed by purified cyclic adenosine 5'-monophosphate dependent bovine cardiac muscle protein kinase and the protein associated with human erythrocyte membranes. phosphorylation occurs when the toxin is dissociated with 5-20 mm dithiothreitol and is restricted to the a1 or "adenylate cyclase activating" subunit of the toxin. | 1976 | 181050 |
| in vitro anamnestic antibody response: differential cellular and calcium requirements for induction by antigen and regulation by cyclic amp. | 1976 | 181149 | |
| characteristics of immunity induced by neuraminidase-treated lymphosarcoma cells in c3h (mtv+) and c3h (mtv-) mice. | the immunogenicity of 6c3hed lymphosarcoma ascites tumor cells was greatly enhanced upon treatment with vibrio cholerae neuraminidase. as a result, mammary tumor virus (mtv)-free c3h mice which had been repeatedly immunized with the treated cells resisted a challenge of 10(6) untreated viable cells inoculated i.p., whereas all control animals died after receiving less than 10 lymphosarcoma tumor cells. in contrast, there was no increase in the refractoriness to challenge when mtv-infected c3h mi ... | 1976 | 181351 |
| interferon action: role of membrane gangliosides. | 1976 | 181911 | |
| trophoblastic pseudotumor of the uterus: an exaggerated form of "syncytial endometritis" simulating a malignant tumor. | twelve cases of a hitherto unrecognized pseudotumorous trophoblastic invasion of the myometrium are analyzed. human chorionic gonadotropin (hcg) was identified by an immunoenzyme technique in the cytoplasm of the invasive cells. the lesion may be localized and only superficially invasive or deeply invasive and have a gross appearance suggesting a neoplasm in the excised uterus. in either case, this process has been confused with various types of malignant tumors, most often choriocarcinoma, from ... | 1976 | 182351 |
| the effects of cholera toxin on the adrenal weight in hypophysectomized rats. | the effects of cholera on adrenal weight in hypophysectomized rats were investigated, in an attempt to demonstrate an acth-like, adrenal trophic effect of the toxin. the results suggested that the toxin probably exerts is acth-like action on the adrenal via adenylate cyclase. cholera toxin was also shown to have a thermolytic action, similar to that of acth, probably due to stimulation of adrenal glucocorticoid secretion. | 1976 | 182572 |
| similarity of responses of cultured sertoli cells to cholera toxin and fsh. | the effects of cholera toxin on the responses of cultured sertoli cells were compared with those elicited by follicle-stimulating hormone (fsh), and n6o2'-dibutyryl-3',5'-cyclic amp (bu2camp). addition of fsh or cholera toxin increased camp levels. subsequently there was greater rates of conversion of testosterone to 17beta-estradiol, formation of androgen-binding protein (abp), and incorporation of [3h]thymidine into dna by sertoli cells prepared from testes of immature rats and cultured in the ... | 1976 | 182580 |
| stimulatory and inhibitory effects of cyclic amp on pancreatic glucagon release from monolayer cultures and the controlling role of calcium. | when glucagon release from monolayer cultures of newborn rat pancreas was measured over four hours in media containing 2.5 mm ca++, a significant cyclic amp-related inhibition of release was observed. this was noted whether intracellular cyclic amp levels were raised by the addition of exogenous cyclic amp or dibutyryl cyclic amp, by phosphodiesterase inhibition with theophylline, or by the stimulation of adenylate cyclase with cholera toxin. the inhibition was concentration dependent for cyclic ... | 1976 | 182608 |
| augmented immunogenicity of tumor cell membranes produced by surface budding viruses: parameters of optimal immunization. | membranes prepared from tumor cells infected with surface budding viruses are much more immunogenic than membranes from uninfected tumor cells. factors affecting immunization with membranes from virus-infected tumor cells were studied. preparations made with influenza virus were clearly superior to those prepared with vesicular stomatitis virus (vsv). membranes infected with vsv were maximally immunogenic at a dose equivalent to a 10% cell pack whereas influenza-virus-infected membranes were imm ... | 1976 | 182646 |
| inflammatory cells in solid murine neoplasms. i. tumor disaggregation and identification of constituent inflammatory cells. | mechanical and enzymatic methods of disaggregating tumors were studied with the goals of (1) minimizing cell losses while (2) maintaining functional and surface membrane markers needed to objectively identify inflammatory cells (ic)1 in resultant suspensions. application of the principles and methods described makes accurate estimation of the percentage of each ic type present in neoplasms possible for the first time. compared to purely mechanical means of disaggregating tumors, all enzyme mixtu ... | 1976 | 182647 |
| the biochemistry of sugars. | in animal cells the utilization of sugars involves one or more of the three major pathways known to occur in these cells. the glycolytic (embden-meyerhof) pathway is quantitatively the most important, and this pathway, coupled to the citric acid cycle, serves as a major source of energy. glycolysis and the citric acid cycle also provide most of the precursors for the synthesis of proteins, nucleic acids and lipids. the pentose phosphate, or hexose monophosphate oxidation, pathway is a major sour ... | 2003 | 182650 |
| studies in a phenotypic female with 17-alpha-hydroxylase deficiency. | in a 19-year-old phenotypic female (46, xy) with hypertension and hypokalemia, studies confirmed 17-alpha-hydroxylase deficiency. prior to diagnosis she had been considered to have testicular feminization. increased plasma progesterone and urinary pregnanediol levels were present before treatment. increased secretion rates of deoxycorticosterone and corticosterone and abnormally low production of cortisol and aldosterone were present. following treatment with hydrocortisone, plasma progesterone, ... | 1991 | 182944 |
| comparison of jc and bk human papovaviruses with simian virus 40: dna homology studies. | studies were performed to ascertain the relationship of human papovavirus jc to bk virus and to simian virus 40 (sv40) by further restriction endonuclease analysis and by dna-dna competition hybridization on membrane filters. form i dna extracted from two new isolates from cases of progressive multifocal leukoencephalopathy of human papovaviruses that were jc-like in their antigenic properties were found to yield restriction endonuclease fragmentation patterns similar to those of prototypic jc v ... | 1976 | 183019 |
| redistribution of immunoglobulin receptors on human neutrophils and its relationship to the release of lysosomal enzymes;. | release of the lysosomal enzyme beta-glucuronidase from human neutrophils was induced by igg or its fc fragment, aggregated by immune precipitation or by coating on latex particles. such release was inhibited when the cells were preincubated with free igg or fc fragments; f(ab')2 fragments were ineffective in both inducing and inhibiting beta-glucuronidase release. neutrophils incubated with igg or fc fragments, when challenged with anti-igg antibody, released lysosomal enzymes without the relea ... | 1976 | 183051 |
| increase of glucagon receptors in hyperthyroidism. | 1976 | 183145 | |
| parametrial calcification in cervical carcinoma patients treated with radioactive gold. | a unique appearance of soft tissue calcification in the pelvis which may be specific for patients treated with parametrial injection of 198au colloid is described. the calcification appears in the area of maximum radiation dose and can appear within 5 years of treatment. it is significant because it occurred in approximately one-half of the cases radiographically reviewed and may be confused with calcification from other etiologies. | 1991 | 183543 |
| cyclic amp and growth of ehrlich ascites tumor cells. lack of cyclic amp elevation in nutritionally deprived cells and mechanism of retardation of growth by dibutryl cyclic amp. | cyclic amp levels in ehrlich ascites tumor cells changed little after deprivation of cells of essential nutrients, serum, glucose and amino acids, deprival of each of which leads to marked inhibition of growth and protein synthesis. cyclic amp levels also changed little after the addition of these nutrients to deprived cells. thus cyclic amp is not likely to be the intracellular mediator for growth regulation by these three nutrients. elevation of cyclic amp levels for short periods by exposure ... | 1976 | 183828 |
| [adenylate cyclase system of the liver]. | 1976 | 183838 | |
| cytomegalovirus hepatitis in an artificial kidney unit. | serum hepatitis is a dreaded risk in connection with regular dialysis treatment (rdt). liver damage, however, can be cuased by other diseases, such as infection with cytomegalovirus (cmv). two cases in our artificial kidney unit revealed signs of liver damage with increased liver enzyme activity. case 1, a woman, was on rdt after an unsuccessful renal transplantation, and case 2, a man, belonged to the staff. serum hepatitis was initially suspected in both cases, but repeated examinations of the ... | 1976 | 184060 |
| cytochrome c peroxidase catalyzed oxidations of substitution inert iron(ii) complexes. | 1989 | 184138 | |
| [lymphographic investigation of the face-neck-region (author's transl)]. | indirect lymphography is shown to be a technically uncomplicated and easy to use method of displaying the lymph nodes and -vessels of the face and neck regions. "lipiodol-ultra-fluid" an oily contrast medium which has used in experiments with minipigs can be radiologically and histologically demonstrated in nodes for months. the histological findings in the course of a year are, at the beginning a phase of non-specific reaction followed by a phase of granulomatous reaction between two weeks and ... | 1990 | 184356 |
| neurophysiological defects in temperature-sensitive paralytic mutants of drosophila melanogaster. | a new temperature-sensitive paralytic mutant of drosophila, comatose, is compared behaviorally and physiologically with the previously known types, para and shi. all three have different properties with respect to kinetics of paralysis at high temperature and recovery from paralysis; com is hypersensitive to paralysis by cooling. neurophysiological experimeents indicate different mechanisms for paralysis in each of the mutants. | 1990 | 184469 |
| [clinical and statistical study of 100 vitiligo patients. i. etiologic factors and clinical study]. | a study of the etiological factors in 100 cases of vitiligo showed female predominance (59%) variable age of onset, absence of radial factor, moderate influence of psychological, physical or endocrine factors, the large number of subjects belonging to group b, a family history in 18% of cases. the morphology site and course of the lesions were also studied. there was no significant correlation between the course of the disease and the various etiological and clinical parameters studied. | 1990 | 184543 |
| [conservative treatment of patients with small cell lung cancer]. | 1983 | 184622 |