Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| risk factors for an outbreak of leptospirosis in california sea lions (zalophus californianus) in california, 2004. | leptospirosis has been reported in california sea lions (zalophus californianus) since 1970; however, the source of infection and mode of transmission remain unknown. to elucidate these features, demographic and environmental risk factors for leptospirosis were evaluated. california sea lion stranding records from northern california for 2004 were used to identify cases of leptospirosis (n = 316) and controls (n = 143). demographic characteristics (age class, sex) and environmental factors, repr ... | 2008 | 18957639 |
| potential for the emergence of japanese encephalitis virus in california. | the potential risk for the introduction and establishment of japanese encephalitis virus (jev) within california is described based on the literature. jev is a mosquito-borne arbovirus endemic to asia that when transmitted to humans can lead to japanese encephalitis (je), a disease affecting mostly children with a fatality rate up to 30%. the geographical expansion of jev in asia along with the recent introduction and rapid spread of west nile virus (wnv) across the united states, demonstrates t ... | 2009 | 18973447 |
| assisted reproduction for couples affected by human immunodeficiency virus in california. | survey results demonstrate that the majority of fertility clinics in california are willing to care for couples affected by human immunodeficiency virus (hiv) if legal restrictions are removed. in response to scientific advances and evolving clinical standards, california reversed the limitations placed on the provision of assisted reproduction for hiv-positive men in 2008. | 2009 | 18973880 |
| delinquent mortgages, neglected swimming pools, and west nile virus, california. | adjustable rate mortgages and the downturn in the california housing market caused a 300% increase in notices of delinquency in bakersfield, kern county. this led to large numbers of neglected swimming pools, which were associated with a 276% increase in the number of human west nile virus cases during the summer of 2007. | 2008 | 18976560 |
| [giuseppe attardi: mitochondrial genetic system and its influence in the study of the mitochondrial diseases]. | aim: to describe the scientific contributions and biography of giuseppe attardi (1923-2008), in particular his work on the human mitochondrial genetic system of crucial importance for the discovery and understanding of the mechanisms that produce the mitochondrial diseases. development: giuseppe attardi was an italian-born medical doctor that worked with outstanding researchers as james watson, francois jacob, and renato dulbecco, all nobel prizes of medicine until 1963 that was promoted to prof ... | 2008 | 18985599 |
| cervical cancer control research in vietnamese american communities. | census data show that the u.s. vietnamese population now exceeds 1,250,000. cervical cancer among vietnamese american women has been identified as an important health disparity. available data indicate the cervical cancer disparity may be due to low papanicolaou (pap) testing rates rather than variations in human papillomavirus infection rates and/or types. the cervical cancer incidence rates among vietnamese and non-latina white women in california during 2000 to 2002 were 14.0 and 7.3 per 100, ... | 2008 | 18990732 |
| a metaphor at midlife: 'the tragedy of the commons' turns 40. | since 1968, when garrett hardin wrote his essay entitled 'the tragedy of the commons', the idea that human reproduction must be brought under the coercive control of state power has been rejected by every government on earth, with the qualified exception of the people's republic of china. the metaphor that hardin used to convey his message, however, has proliferated, adapted and evolved. its original neo-malthusian message now largely forgotten, 'the tragedy of the commons' has become a wildly p ... | 2008 | 18996596 |
| cruel and unusual punishment: distinguishing distributive and retributive justice. | 2008 | 19004436 | |
| avian flu school: a training approach to prepare for h5n1 highly pathogenic avian influenza. | since the reemergence of highly pathogenic avian influenza (h5n1 hpai) in 2003, a panzootic that is historically unprecedented in the number of infected flocks, geographic spread, and economic consequences for agriculture has developed. the epidemic has affected a wide range of birds and mammals, including humans. the ineffective management of outbreaks, mainly due to a lack of knowledge among those involved in detection, prevention, and response, points to the need for training on h5n1 hpai. th ... | 2008 | 19006974 |
| risk factors for infection with pathogenic and antimicrobial-resistant fecal bacteria in northern elephant seals in california. | the goal of this study was to identify potential environmental and demographic factors associated with campylobacter jejuni (c. jejuni), salmonella enterica (salmonella spp.), and antimicrobial-resistant escherichia coli (e. coli) infection in northern elephant seals stranded along the california coastline. | 2008 | 19006978 |
| sesquiterpenes from the sponge axinyssa isabela. | further research on the constituents of the sponge axinyssa isabela collected in the gulf of california has led to the isolation of nine new sesquiterpenes, the eudesmanes axinisothiocyanates m and n (1, 2), the bisabolane axinythiocyanate a (3), and the aristolane derivatives axinysones a-e (4-8) and axinynitrile a (9), together with four known sesquiterpenoids (10-13). the structures of the new metabolites have been established by spectroscopic techniques.the absolute configuration of axinyson ... | 2008 | 19007287 |
| understanding and managing experiential aspects of soundscapes at muir woods national monument. | research has found that human-caused noise can detract from the quality of the visitor experience in national parks and related areas. moreover, impacts to the visitor experience can be managed by formulating indicators and standards of quality as suggested in park and outdoor recreation management frameworks, such as visitor experience and resource protection (verp), as developed by the u.s. national park service. the research reported in this article supports the formulation of indicators and ... | 2009 | 19020928 |
| elevated house dust and serum concentrations of pbdes in california: unintended consequences of furniture flammability standards? | studies show higher house dust and body burden levels of pbde flame retardants in north america than europe; but little is known about exposure variation within north america, where california's furniture flammability standard affects pbde use. we compared dust samples from 49 homes in two california communities with 120 massachusetts homes and with other published studies. dust concentrations [median (range) ng/g] in california homes of bde-47, -99, and -100 were 2700 (112-107,000), 3800 (102-1 ... | 2008 | 19031918 |
| risks for cervical intraepithelial neoplasia 3 among adolescents and young women with abnormal cytology. | to estimate the risks of cervical intraepithelial neoplasia (cin) 3 among girls and women aged 13 to 24 years who were referred for abnormal cytology while receiving care in a large health maintenance organization. | 2008 | 19037044 |
| sexual solicitation of latino male day laborers by other men. | to examine the likelihood of latino day laborers being solicited for sex by other men. | 2008 | 19039432 |
| enzootic rabies elimination from dogs and reemergence in wild terrestrial carnivores, united states. | to provide molecular and virologic evidence that domestic dog rabies is no longer enzootic to the united states and to identify putative relatives of dog-related rabies viruses (rvs) circulating in other carnivores, we studied rvs associated with recent and historic dog rabies enzootics worldwide. molecular, phylogenetic, and epizootiologic evidence shows that domestic dog rabies is no longer enzootic to the united states. nonetheless, our data suggest that independent rabies enzootics are now e ... | 2008 | 19046506 |
| new rabies virus variant in mexican immigrant. | a novel rabies virus was identified after death in a man who had immigrated from oaxaca, mexico, to california, usa. despite the patient's history of exposure to domestic and wild carnivores, molecular and phylogenetic characterizations suggested that the virus originated from insectivorous bats. enhanced surveillance is needed to elucidate likely reservoirs. | 2008 | 19046517 |
| does variation in culex (diptera: culicidae) vector competence enable outbreaks of west nile virus in california? | since the invasion of california by west nile virus (family flaviviridae, genus flavivirus, wnv) in 2003, we have annually monitored vector competence for the ny99 strain in culex tarsalis coquillett, culex pipiens quinquefasciatus say, culex p. pipiens l., and culex stigmatosoma dyar populations from four areas: deserts of coachella valley, densely urbanized maritime los angeles, southern san joaquin valley in kern county, and southern sacramento valley near davis in sacramento county. overall, ... | 2008 | 19058638 |
| low stage follicular lymphoma: biologic and clinical characterization according to nodal or extranodal primary origin. | studies suggest that primary extranodal follicular lymphoma (fl) is not infrequent but it remains poorly characterized with variable histologic, molecular, and clinical outcome findings. we compared 27 extranodal fl to 44 nodal fl using morphologic, immunohistochemical, and molecular genetic techniques and evaluated the clinical outcome of these 2 similarly staged groups. eight cases of primary cutaneous follicle center lymphoma were also studied. in comparison to nodal fl, a greater number of e ... | 2009 | 19065102 |
| chromosomal abnormalities among children born with conotruncal cardiac defects. | conotruncal heart defects compose 25% to 30% of nonsyndromic congenital heart defects. this study describes the frequency of chromosome abnormalities and microdeletion of 22q11 associated among infants and fetuses delivered with conotruncal heart malformations. | 2009 | 19067405 |
| simulating extracorporeal membrane oxygenation emergencies to improve human performance. part i: methodologic and technologic innovations. | extracorporeal membrane oxygenation (ecmo) is a form of long-term cardiopulmonary bypass used to treat infants, children, and adults with respiratory and/or cardiac failure despite maximal medical therapy. mechanical emergencies on extracorporeal membrane oxygenation (ecmo) have an associated mortality of 25%. thus, acquiring and maintaining the technical, behavioral, and critical thinking skills necessary to manage ecmo emergencies is essential to patient survival. traditional training in ecmo ... | 2006 | 19088593 |
| simulating extracorporeal membrane oxygenation emergencies to improve human performance. part ii: assessment of technical and behavioral skills. | healthcare professionals are expected to make rapid, correct decisions in critical situations despite what may be a lack of real practical experience in a particular crisis situation. successful resolution of a medical crisis depends upon demonstration not only of appropriate technical skills but also of key behavioral skills (eg, leadership, communication, and teamwork). we have developed a hands-on, high fidelity, simulation-based training program (ecmo sim) to provide healthcare professionals ... | 2006 | 19088594 |
| a public health model for the molecular surveillance of hiv transmission in san diego, california. | current public health efforts often use molecular technologies to identify and contain communicable disease networks, but not for hiv. here, we investigate how molecular epidemiology can be used to identify highly related hiv networks within a population and how voluntary contact tracing of sexual partners can be used to selectively target these networks. | 2009 | 19098493 |
| polybrominated diphenyl ether flame retardants in the u.s. marine environment: a review. | polybrominated diphenyl ethers (pbdes) are used as flame retardants in polymeric materials such as furnishing foam, rigid plastics and textiles. the u.s. has historically led the world production of these man-made chemicals and was responsible for about 50% of the total global demand in 2001. paradoxically, scientific studies addressing sources, behavior and fate of pbdes in the u.s. environment are limited when compared to those in europe. this paper reviews the distribution of pbdes in marine ... | 2009 | 19100622 |
| an area-level model of vehicle-pedestrian injury collisions with implications for land use and transportation planning. | there is growing awareness among urban planning, public health, and transportation professionals that design decisions and investments that promote walking can be beneficial for human and ecological health. planners need practical tools to consider the impact of development on pedestrian safety, a key requirement for the promotion of walking. simple bivariate models have been used to predict changes in vehicle-pedestrian injury collisions based on changes in traffic volume. we describe the devel ... | 2009 | 19114148 |
| evaluation of the first year of a pilot program in community pharmacy: hiv/aids medication therapy management for medi-cal beneficiaries. | the advent of combined antiretroviral therapy (art) has increased treatment effectiveness but created new challenges for patients infected with human immunodeficiency virus (hiv) and for community pharmacists managing patients' drug therapy. the ability of pharmacist-provided medication therapy management (mtm) services to increase medication adherence, improve health outcomes, and reduce overall medical costs has been demonstrated in community pharmacies for chronic diseases such as diabetes an ... | 2009 | 19125548 |
| zoonotic bartonella species in fleas collected on gray foxes (urocyon cinereoargenteus). | bartonella spp. are fastidious, gram-negative, rod-shaped bacteria and are usually vector-borne. however, the vector has not been definitively identified for many recently described species. in northern california, gray foxes (urocyon cinereoargenteus) are infected with two zoonotic bartonella species, b. rochalimae and b. vinsonii subsp. berkhoffii. fleas (range 1-8 fleas per fox) were collected from 22 (41.5%) of 54 gray foxes from urban and backcountry zones near hoopa, california. the flea s ... | 2009 | 19125660 |
| frequency and etiology of solitary hot spots in the pelvis at whole-body positron emission tomography/computed tomography imaging. | to determine the frequency and etiology of a single hypermetabolic focus within the pelvis with no other areas of increased 18-fluorodeoxyglucose (fdg) uptake in the reminder of the whole body in an oncological population. | 2009 | 19135929 |
| biogeographic patterns in genomic diversity among a large collection of vibrio cholerae isolates. | vibrio cholerae strains are capable of inhabiting multiple niches in the aquatic environment and in some cases cause disease in humans. however, the ecology and biodiversity of these bacteria in environmental settings remains poorly understood. we used the genomic fingerprinting technique enterobacterial repetitive intergenic consensus sequence pcr (eric-pcr) to profile 835 environmental isolates from waters and sediments obtained at nine sites along the central california coast. we identified 1 ... | 2009 | 19139224 |
| human physique and sexual attractiveness in men and women: a new zealand-u.s. comparative study. | men and women living in new zealand and california completed five studies regarding human physique and sexual attractiveness. in studies 1-3, women rated images of male stimuli and, in studies 4-5, men rated female stimuli. in study 1, women in both countries rated mesomorphic (muscular) and average male somatotypes as most attractive, followed by ectomorphic (slim) and endomorphic (heavily built) figures. in study 2, amount and distribution of masculine trunk hair (chest and abdominal) was alte ... | 2010 | 19139985 |
| a randomized controlled trial evaluating an alternative mouse or forearm support on change in median and ulnar nerve motor latency at the wrist. | the purpose of this study was to determine the effects of an alternative mouse and/or a forearm support board on nerve function at the wrist among engineers. | 2009 | 19142961 |
| polychlorinated biphenyls (pcbs) and their hydroxylated metabolites (oh-pcbs) in livers of harbor seals (phoca vitulina) from san francisco bay, california and gulf of maine. | bioaccumulation of endocrine disruptors in marine mammals positioned at the top of the food chain is of toxicological concern. livers from four pups and ten adult harbor seals (phoca vitulina) stranded in san francisco bay (sfb) and the gulf of maine (gom) were analyzed for polychlorinated biphenyls (pcbs) and their hydroxylated metabolites (oh-pcbs). we used gc-ecd and gc-nci/ms to investigate the presence of 28 pcbs and 8 oh-pcb metabolites, respectively. sigma(28)pcb concentrations (di- to oc ... | 2009 | 19150735 |
| genetic polymorphisms in the thioredoxin 2 (txn2) gene and risk for spina bifida. | txn2 encodes human thioredoxin 2, a small redox protein important in cellular antioxidant defenses, as well as in the regulation of apoptosis. txn2 knockout mice fail to complete neural tube closure by e10.5 and die in utero. we hypothesized that genetic variation in human txn2 gene may alter the function of the encoded protein in a manner associated with an increased risk for neural tube defects (ntds). a dna re-sequencing effort of the human txn2 gene was taken. after a variation in the promot ... | 2009 | 19165900 |
| prevalence and correlates of unknown hiv infection among patients seeking care in a public hospital emergency department. | screening for human immunodeficiency virus (hiv) infection in the emergency department (ed) has been proposed as an effective approach to increase early hiv diagnosis. to evaluate the potential for the implementation of routine screening, we determined the prevalence of unknown hiv infection among patients being seen in an urban public hospital ed. | 2008 | 19166088 |
| rapid hiv testing in transgender communities by community-based organizations in three cities. | this article describes the demographic and behavioral characteristics, human immunodeficiency virus (hiv) testing history, and results of hiv testing of transgender (tg) people recruited for rapid hiv testing by community-based organizations (cbos) in three cities. | 2008 | 19166094 |
| spatial spreading of west nile virus described by traveling waves. | in this work, we propose a spatial model to analyze the west nile virus propagation across the usa, from east to west. west nile virus is an arthropod-borne flavivirus that appeared for the first time in new york city in the summer of 1999 and then spread prolifically among birds. mammals, such as humans and horses, do not develop sufficiently high bloodstream titers to play a significant role in the transmission, which is the reason to consider the mosquito-bird cycle. the model aims to study t ... | 2009 | 19167405 |
| local veterinary diagnostic laboratory, a model for the one health initiative. | the san diego county animal disease diagnostic laboratory (addl) is unique in its emphasis on protecting both human and animal health in san diego county, and its use of interagency and community collaboration to create strong, effective public health programs. this article describes the addl core programs of avian and vector-borne disease surveillance, rabies testing, and animal abuse investigations and uses selected case studies to illustrate the need for a local veterinary diagnostic laborato ... | 2009 | 19185199 |
| distribution and diversity of the enterococcal surface protein (esp) gene in animal hosts and the pacific coast environment. | this study sought to evaluate the distribution of the enterococcal surface protein (esp) gene in enterococcus faecium in the pacific coast environment as well as the distribution and diversity of the gene in northern california animal hosts. | 2009 | 19187132 |
| repeated west nile virus epidemic transmission in kern county, california, 2004-2007. | west nile virus (wnv) has remained epidemic in kern county, ca, since its introduction in 2004 through 2007 when the human case annual incidence increased from 6-8 to 17 per 100,000, respectively. the 2007 increase in human infection was associated with contradicting surveillance indicators, including severe drought, warm spring but cool summer temperature anomalies, decreased rural and urban mosquito abundance but increased early season infection in urban culex quinquefasciatus say, moderate av ... | 2009 | 19198528 |
| multimedia transport and risk assessment of organophosphate pesticides and a case study in the northern san joaquin valley of california. | this paper presents a framework for cumulative risk characterization of human exposure to pesticides through multiple exposure pathways. this framework is illustrated through a case study of selected organophosphate (op) pesticides in the northern san joaquin valley of california. chemical concentrations in environmental media were simulated using a multimedia environmental fate model, and converted to contamination levels in exposure media. the risk characterization in this study was based on a ... | 2009 | 19211125 |
| integrative therapies in hospice and home health: introduction and adoption. | integrative therapies comprise a variety of nonpharmacologic methods that provide pain and symptom management. these therapies are increasingly gaining acceptance in the healthcare community as complementary to traditional treatments for pain. this article details the introduction, scope, and challenges healthcare organizations face when incorporating integrative therapies into their care plans. | 2009 | 19212218 |
| prognostic impact of human epidermal growth factor-like receptor 2 and hormone receptor status in inflammatory breast cancer (ibc): analysis of 2,014 ibc patient cases from the california cancer registry. | inflammatory breast cancer (ibc) is an aggressive form of breast cancer associated with overexpression of her2/neu (human epidermal growth factor-like receptor 2 (her2)) and poor survival. we investigated survival differences for ibc patient cases based on hormone receptor status and her2 receptor status using data from the california cancer registry, as contrasted with locally advanced breast cancer (labc), metastatic breast cancer (mbc) and non-t4 breast cancer. | 2009 | 19228416 |
| storm drains are sources of human fecal pollution during dry weather in three urban southern california watersheds. | coastal urbanized areas in southern california experience frequent beach water quality warnings in summer due to high concentrations of fecal indicator bacteria (fib). remediation can be difficult, as sources are often unknown. during two summers, we sampled three urbanized watersheds in santa barbara, ca at sites with historically high fib concentrations to determine if human fecal matter was influencing water quality. by quantification of a human-specific bacteroides marker (hbm), human waste ... | 2009 | 19238954 |
| courts. man denied release from hospital partly due to hiv delusions. | 2009 | 19255979 | |
| evaluation of a human on-site urine multidrug test for emergency use with dogs. | a rapid, human on-site urine multidrug test was used to screen canine urine samples for the presence of five illegal drugs and drugs from three commonly abused drug classes. each sample was sent to a toxicology laboratory for gas chromatography/mass spectrometry (gc/ms) validation. on-site test results and gc/ms assays confirmed that the human on-site test kit did identify barbiturates, opiates, benzodiazepines, and amphetamines/methamphetamines in urine from dogs that had received these common ... | 2009 | 19258416 |
| methicillin-resistant staphylococcus aureus skin infections from an elephant calf--san diego, california, 2008. | methicillin-resistant staphylococcus aureus (mrsa) infections are a major cause of human skin and soft tissue infections in the united states. mrsa colonization and infection also have been observed in turtles, bats, seals, sheep, rabbits, rodents, cats, dogs, pigs, birds, horses, and cattle, and mrsa infections with an epidemiologic link to animal contact have been reported in veterinary personnel, pet owners, and farm animal workers. on january 29, 2008, the county of san diego health and huma ... | 2009 | 19265780 |
| parkinson's disease and residential exposure to maneb and paraquat from agricultural applications in the central valley of california. | evidence from animal and cell models suggests that pesticides cause a neurodegenerative process leading to parkinson's disease (pd). human data are insufficient to support this claim for any specific pesticide, largely because of challenges in exposure assessment. the authors developed and validated an exposure assessment tool based on geographic information systems that integrated information from california pesticide use reports and land-use maps to estimate historical exposure to agricultural ... | 2009 | 19270050 |
| cyp1a1/2 haplotypes and lung cancer and assessment of confounding by population stratification. | prior studies of lung cancer and cyp1a1/2 in african-american and latino populations have shown inconsistent results and have not yet investigated the haplotype block structure of cyp1a1/2 or addressed potential population stratification. to investigate haplotypes in the cyp1a1/2 region and lung cancer in african-americans and latinos, we conducted a case-control study (1998-2003). african-americans (n = 535) and latinos (n = 412) were frequency matched on age, sex, and self-reported race/ethnic ... | 2009 | 19276377 |
| sex differences in humeral bilateral asymmetry in two hunter-gatherer populations: california amerinds and british columbian amerinds. | this study uses two prehistoric amerindian populations of hunter-gatherer subsistence patterns to determine whether levels of sexual dimorphism in humeral bilateral cross-sectional asymmetry are related to sex-specific differences in activities among these populations. results confirmed that males of the california amerind population who engaged in the more unimanual activities of spear hunting and warfare were more asymmetrical than were their female counterparts who engaged in the more bimanua ... | 2009 | 19280674 |
| reptile infection with anaplasma phagocytophilum, the causative agent of granulocytic anaplasmosis. | granulocytic anaplasmosis (ga) is a potentially fatal tick-borne rickettsial disease that occurs sporadically in the far western united states. we evaluated the prevalence of anaplasma phagocytophilum in multiple species of lizards and snakes from enzootic sites in northern california, described the infestation prevalence of its tick vector ixodes pacificus on reptiles, and conducted an experimental challenge of western fence lizards (sceloporus occidentalis) and pacific gopher snakes (pituophis ... | 2009 | 19281295 |
| one in four california adolescent girls have had human papillomavirus vaccination. | 2009 | 19288623 | |
| resuscitation of likely nonviable newborns: would neonatology practices in california change if the born-alive infants protection act were enforced? | the effects of the born-alive infants protection act of 2002, which defines the legal status of live-born infants have not been evaluated. | 2009 | 19336366 |
| long-term historical analysis of benthic communities and physical habitat in an agricultural stream in california's san joaquin river watershed. | this study was designed to characterize long-term annual temporal and spatial trends (2001 to 2007) in physical habitat and benthic communities and to determine relationships of habitat and benthic communities during this 7-year period in an agricultural stream in the san joaquin river watershed in california (del puerto creek). the canonical discriminant analysis indicated that there were no overall significant temporal patterns for the habitat metrics although spatial patterns were prominent f ... | 2009 | 19337917 |
| dispersion of response times reveals cognitive dynamics. | trial-to-trial variation in word-pronunciation times exhibits 1/f scaling. one explanation is that human performances are consequent on multiplicative interactions among interdependent processes-interaction dominant dynamics. this article describes simulated distributions of pronunciation times in a further test for multiplicative interactions and interdependence. individual participant distributions of approximately 1,100 word-pronunciation times were successfully mimicked for each participant ... | 2009 | 19348544 |
| mercury contamination in three species of anuran amphibians from the cache creek watershed, california, usa. | fish and wildlife may bioaccumulate mercury (hg) to levels that adversely affect reproduction, growth, and survival. sources of hg within the cache creek watershed in northern california have been identified, and concentrations of hg in invertebrates and fish have been documented. however, bioaccumulation of hg by amphibians has not been evaluated. in this study, adult and juvenile american bullfrogs (lithobates catesbeianus) and foothill yellow-legged frogs (rana boylii), adult northern pacific ... | 2010 | 19353298 |
| swine influenza a (h1n1) infection in two children--southern california, march-april 2009. | on april 17, 2009, cdc determined that two cases of febrile respiratory illness occurring in children who resided in adjacent counties in southern california were caused by infection with a swine influenza a (h1n1) virus. the viruses from the two cases are closely related genetically, resistant to amantadine and rimantadine, and contain a unique combination of gene segments that previously has not been reported among swine or human influenza viruses in the united states or elsewhere. neither chi ... | 2009 | 19390508 |
| ecology of anaplasma phagocytophilum infection in gray foxes (urocyon cinereoargenteus) in northwestern california. | although granulocytic anaplasmosis, caused by infection of anaplasma phagocytophilum, is an emerging human and domestic animal disease, the ecology and natural history of the parasite is not well understood. gray foxes (urocyon cinereoargenteus) are relatively common, occasionally peri-urban mesocarnivores whose geographic distribution overlaps the reported distribution of granulocytic anaplasmosis in humans and domestic animals in north america. we evaluated the potential of foxes as hosts and ... | 2009 | 19395744 |
| availability of hiv postexposure prophylaxis services in los angeles county. | postexposure prophylaxis after sexual exposure to human immunodeficiency virus (hiv) is recommended by state and national agencies. a cross-sectional survey of 117 los angeles county sites found that 17 sites (14.5%) offer postexposure prophylaxis. ten sites (8.5%) offer postexposure prophylaxis to patients who are uninsured. general availability of postexposure prophylaxis should be a public health priority. | 2009 | 19400685 |
| update: infections with a swine-origin influenza a (h1n1) virus--united states and other countries, april 28, 2009. | since april 21, 2009, cdc has reported cases of respiratory infection with a swine-origin influenza a (h1n1) virus (s-oiv) transmitted through human-to-human contact. this report updates cases identified in u.s. states and highlights certain control measures taken by cdc. as of april 28, the total number of confirmed cases of s-oiv infection in the united states had increased to 64, with cases in california (10 cases), kansas (two), new york (45), ohio (one), and texas (six). cdc and state and l ... | 2009 | 19407737 |
| update: drug susceptibility of swine-origin influenza a (h1n1) viruses, april 2009. | since april 21, 2009, cdc has reported cases of respiratory infection with a swine-origin influenza a (h1n1) virus (s-oiv) that is being spread via human-to-human transmission. as of april 28, the total number of confirmed s-oiv cases in the united states was 64; these cases occurred in california (10 cases), kansas (two), new york (45), ohio (one), and texas (six). the viruses contain a unique combination of gene segments that had not been reported previously among swine or human influenza viru ... | 2009 | 19407738 |
| update: swine influenza a (h1n1) infections--california and texas, april 2009. | on april 21, 2009, cdc reported that two recent cases of febrile respiratory illness in children in southern california had been caused by infection with genetically similar swine influenza a (h1n1) viruses. the viruses contained a unique combination of gene segments that had not been reported previously among swine or human influenza viruses in the united states or elsewhere. neither child had known contact with pigs, resulting in concern that human-to-human transmission might have occurred. th ... | 2009 | 19407739 |
| changes in sediment and organic carbon accumulation in a highly-disturbed ecosystem: the sacramento-san joaquin river delta (california, usa). | we used the sacramento-san joaquin river delta ca (delta, hereafter) as a model system for understanding how human activities influence the delivery of sediment and total organic carbon (toc) over the past 50-60 years. sediment cores were collected from sites within the delta representing the sacramento river (sac), the san joaquin river (sjr), and franks tract (ft), a flooded agricultural tract. a variety of anthropogenic tracers including (137)cs, total dde (sigma dde) and brominated diphenyl ... | 2009 | 19409575 |
| the 'millionaires tax' and mental health policy in california. | despite long-standing and widespread opposition to new taxes, in 2004 californians approved a so-called millionaires tax, levied on those with taxable net income over $1 million. the proceeds, estimated to be $700 million to $1 billion per year, can only be spent on improving mental health services for people with or at risk of a disabling mental disorder. progress has been made in access to services, prevention programs, supported housing, and integrating mental health with the other human serv ... | 2009 | 19414891 |
| accuracy and precision of the volume-concentration method for urban stormwater modeling. | land use based models have been widely used to estimate stormwater pollutant loads for establishing standards and selecting best management practices. land use information is required to assign imperviousness or runoff coefficients and event mean concentrations for selected pollutants to the areas of the watersheds. this approach is useful to estimate the total mass discharges, but is dependent on various assumptions for parameters, which have rarely been validated with full-scale field data. th ... | 2009 | 19439339 |
| hydroxylated pcb metabolites (oh-pcbs) in archived serum from 1950-60s california mothers: a pilot study. | we are studying participants selected from the child health and development studies (chds), a longitudinal birth cohort of over 20,000 california pregnancies between 1959 and 1967, for associations between maternal body burden of organochlorine contaminants and thyroid function. we designed a pilot study using 30 samples selected among samples with high and low pcb concentrations to evaluate the feasibility of measuring oh-pcbs in the larger study population. gc-ecd and gc-nci/ms were used to de ... | 2009 | 19439357 |
| swine-origin influenza a (h1n1) virus infections in a school - new york city, april 2009. | on april 24, 2009, cdc reported eight confirmed cases of swine-origin influenza a (h1n1) virus (s-oiv) infection in texas and california. the strain identified in u.s. patients was confirmed by cdc as genetically similar to viruses subsequently isolated from patients in mexico. since april 24, the number of cases in the united states and elsewhere has continued to rise. as of april 28, approximately half (45) of all u.s. cases of s-oiv infection had been confirmed among students and staff member ... | 2009 | 19444151 |
| tumor markers and rectal cancer: support for an inflammation-related pathway. | inflammation may be a key element in the etiology of colorectal cancer. in our study, we examine associations between factors related to inflammation and specific rectal cancer mutations. a population-based study of 750 rectal cancer cases with interview and tumor dna were compared to 1,205 population-based controls. study participants were from utah and the northern california kaiser permanente medical care program. tumor dna was analyzed for tp53 and kras2 mutations and cpg island methylator p ... | 2009 | 19452524 |
| migration patterns of the emerging plant pathogen phytophthora ramorum on the west coast of the united states of america. | phytophthora ramorum (oomycetes) is the causal agent of sudden oak death and ramorum blight on trees, shrubs, and woody ornamentals in the forests of coastal california and southwestern oregon and in nurseries of california, oregon, and washington. in this study, we investigated the genetic structure of p. ramorum on the west coast of the united states, focusing particularly on population differentiation potentially indicative of gene flow. in total, 576 isolates recovered from 2001 to 2005 were ... | 2009 | 19453234 |
| the basis for ecotoxicological concern in aquatic ecosystems contaminated by historical mercury mining. | the coast range of california is one of five global regions that dominated historical production of mercury (hg) until declining demand led to the economic collapse of the hg-mining industry in the united states. calcines, waste rock, and contaminated alluvium from inactive mine sites can release hg (including methylmercury, mehg) to the environment for decades to centuries after mining has ceased. soils, water, and sediment near mines often contain high concentrations of total hg (tothg), and a ... | 2008 | 19475915 |
| the legacy of mercury cycling from mining sources in an aquatic ecosystem: from ore to organism. | clear lake is the site of an abandoned mercury (hg) mine (active intermittently from 1873 to 1957), now a u.s. environmental protection agency superfund site. mining activities, including bulldozing waste rock and tailings into the lake, resulted in approximately 100 mg of hg entering the lake's ecosystem. this series of papers represents the culmination of approximately 15 years of hg-related studies on this ecosystem, following hg from the ore body to the highest trophic levels. a series of ph ... | 2008 | 19475916 |
| mercury in abiotic matrices of clear lake, california: human health and ecotoxicological implications. | mercury (hg) from hg mining at clear lake, california, usa, has contaminated water and sediments for over 130 years and has the potential to affect human and environmental health. with total mercury (tothg) concentrations up to 438 mg/kg (dry mass) in surficial sediments and up to 399 ng/l in lake water, clear lake is one of the most hg-contaminated lakes worldwide. particulate hg in surface water near the mine ranges from 10,000 to 64,000 ng/g; tothg declines exponentially with distance from th ... | 2008 | 19475922 |
| spatiotemporal trends in fish mercury from a mine-dominated ecosystem: clear lake, california. | clear lake, california, usa, receives acid mine drainage and mercury (hg) from the sulphur bank mercury mine, a u.s. environmental protection agency (u.s. epa) superfund site that was active intermittently from 1873 to 1957 and partially remediated in 1992. mercury concentrations were analyzed primarily in four species of clear lake fishes: inland silversides (menidia beryllina, planktivore), common carp (cyprinus carpio, benthic scavenger/omnivore), channel catfish (ictalurus punctatus, benthic ... | 2008 | 19475924 |
| mercury residues and productivity in osprey and grebes from a mine-dominated ecosystem. | mercury (hg) and reproduction and status of western and clark's grebes (aechmophorus sp.) and osprey (pandion haliaetus) were studied from 1992 through 2001 and then less intensely through 2006 at clear lake, california, usa. remediation to reduce hg loading from the sulphur bank mercury mine was initiated in 1992. mercury in grebe feathers declined monotonically from approximately 23 mg/kg dry mass (dm) in 1967-1969 to 1 mg/kg in 2003, but then increased to 7 mg/kg in 2004-2006. mercury in ospr ... | 2008 | 19475927 |
| clear lake sediments: anthropogenic changes in physical sedimentology and magnetic response. | we analyzed the sedimentological characteristics and magnetic properties of cores from the three basins of clear lake, california, usa, to assess the depositional response to a series of land use changes that occurred in the watershed over the 20th century. results indicate that distinct and abrupt shifts in particle size, magnetic concentration/mineralogy, and redox conditions occur concurrently with a variety of ecological and chemical changes in lake bed sediments. this coincidence of events ... | 2008 | 19475928 |
| anthropogenic stressors and changes in the clear lake ecosystem as recorded in sediment cores. | sediment cores were collected to investigate multiple stresses on clear lake, california, usa, through the period of european occupation to the present day. earlier workers suggested the hypothesis that the use of mechanized earthmoving equipment, starting in the 1920s and 1930s, was responsible for erosion, mercury (hg) contamination, and habitat loss stresses. cores (approximately 2.5 m in depth) were collected in 1996 and 2000 from each of the three arms of the lake. carbon-14 dating suggests ... | 2008 | 19475929 |
| vertical stability of mercury in historic and prehistoric sediments from clear lake, california. | clear lake, california, usa, is the site of the sulphur bank mercury mine, now a u.s. environmental protection agency superfund site. intermittent mining from 1873 to 1957 resulted in approximately 100 mg of mercury (hg) being deposited into the lake's ecosystem. sediment cores to approximately 2.5 m depth (dated using 210pb and 14c) represent approximately 3000 years of sedimentation. clear lake sediments have experienced hg deposition from anthropogenic sources (mining) during historic times ( ... | 2008 | 19475930 |
| hospitalized patients with novel influenza a (h1n1) virus infection - california, april-may, 2009. | since april 15 and 17, 2009, when the first two cases of novel influenza a (h1n1) infection were identified from two southern california counties, novel influenza a (h1n1) cases have been documented throughout the world, with most cases occurring in the united states and mexico. in the united states, early reports of illnesses associated with novel influenza a (h1n1) infection indicated the disease might be similar in severity to seasonal influenza, with the majority of patients not requiring ho ... | 2009 | 19478723 |
| atmospheric chemistry: the man who smells forests. | 2009 | 19478760 | |
| what's needed next: a culture of candor. | if there's one thing that the past decade's business disasters should teach us, it's that we need to stop evaluating corporate leaders simply on the basis of how much wealth they create for investors. a healthier yardstick would be this: the extent to which leaders create firms that are economically, ethically, and socially sustainable. the first step toward accomplishing that task is to create a culture of candor. companies can't innovate, respond to stakeholder needs, or run efficiently unless ... | 2009 | 19496471 |
| new perspectives in human stem cell therapeutic research. | human stem cells are in evaluation in clinical stem cell trials, primarily as autologous bone marrow studies, autologous and allogenic mesenchymal stem cell trials, and some allogenic neural stem cell transplantation projects. safety and efficacy are being addressed for a number of disease state applications. there is considerable data supporting safety of bone marrow and mesenchymal stem cell transplants but the efficacy data are variable and of mixed benefit. mechanisms of action of many of th ... | 2009 | 19519878 |
| bartonella quintana in body lice and head lice from homeless persons, san francisco, california, usa. | bartonella quintana is a bacterium that causes trench fever in humans. past reports have shown bartonella spp. infections in homeless populations in san francisco, california, usa. the california department of public health in collaboration with san francisco project homeless connect initiated a program in 2007 to collect lice from the homeless to test for b. quintana and to educate the homeless and their caregivers on prevention and control of louse-borne disease. during 2007-2008, 33.3% of bod ... | 2009 | 19523290 |
| the incidence and clinical characteristics of herpes zoster among children and adolescents after implementation of varicella vaccination. | the varicella-zoster virus (vzv) vaccine strain may reactivate to cause herpes zoster. limited data suggest that the risk of herpes zoster in vaccinated children could be lower than in children with naturally acquired varicella. we examine incidence trends, risk and epidemiologic and clinical features of herpes zoster disease among children and adolescents by vaccination status. | 2009 | 19536039 |
| the complete genome of klassevirus - a novel picornavirus in pediatric stool. | diarrhea kills 2 million children worldwide each year, yet an etiological agent is not found in approximately 30-50% of cases. picornaviral genera such as enterovirus, kobuvirus, cosavirus, parechovirus, hepatovirus, teschovirus, and cardiovirus have all been found in human and animal diarrhea. modern technologies, especially deep sequencing, allow rapid, high-throughput screening of clinical samples such as stool for new infectious agents associated with human disease. | 2009 | 19538752 |
| a prospective, multicenter, randomized trial to assess efficacy of pioglitazone on in-stent neointimal suppression in type 2 diabetes: popps (prevention of in-stent neointimal proliferation by pioglitazone study). | the aim of this study was to clarify whether pioglitazone suppresses in-stent neointimal proliferation and reduces restenosis and target lesion revascularization (tlr) after percutaneous coronary intervention (pci). | 2009 | 19539256 |
| trophy-taking and dismemberment as warfare strategies in prehistoric central california. | we document evidence for trophy-taking and dismemberment with a new bioarchaeological database featuring 13,453 individuals from prehistoric central california sites. our study reveals 76 individuals with perimortem removal of body parts consistent with trophy-taking or dismemberment; nine of these individuals display multiple types of trophy-taking and dismemberment for a total of 87 cases. cases span almost 5,000 years, from the early period (3000-500 bc) to the late period (ad 900-1700). coll ... | 2010 | 19544576 |
| fishing from past to present: continuity and resilience of red abalone fisheries on the channel islands, california. | archaeological data from coastal shell middens provide a window into the structure of ancient marine ecosystems and the nature of human impacts on fisheries that often span millennia. for decades channel island archaeologists have studied middle holocene shell middens visually dominated by large and often whole shells of the red abalone (haliotis rufescens). here we use modern ecological data, historical accounts, commercial red abalone catch records, and zooarchaeological data to examine long-t ... | 2009 | 19544733 |
| role of metabolic syndrome components in human immunodeficiency virus-associated stroke. | metabolic syndrome (mets) is a cluster of risk factors, including elevated mean arterial pressure (map), atherogenic dyslipidemia (elevated triglycerides [trg]), abdominal obesity (increased body mass index [bmi]), glucose intolerance (elevated glucose [glu]), and prothrombotic/inflammatory state (increases in uric acid [ua]), that are associated with increased risk of cerebrovascular disease. we studied if an association existed between mets components and human immunodeficiency virus (hiv)-ass ... | 2009 | 19562611 |
| a multimodal aging and dying course for first-year medical students improves knowledge and attitudes. | when medical schools change their curricula, this opens up opportunities for the development of new material and often eliminates previously designed courses. emory university's school of medicine revised its curriculum in 2007, combining clinical medicine and basic sciences in the first 18 months. as part of its first section on "the healthy human," it included a weeklong module on aging. the main objective of this study was to evaluate attitudes and knowledge about aging issues before and afte ... | 2009 | 19563520 |
| rapid-test sensitivity for novel swine-origin influenza a (h1n1) virus in humans. | 2009 | 19564634 | |
| percutaneous suture edge-to-edge repair of the mitral valve. | to describe a new approach to percutaneous mitral valve repair and an illustrative first-in-man experience, we introduce a suture mediated "double orifice", "edge-to-edge" procedure which can be an effective surgical therapy for mitral regurgitation (mr) in selected patient. | 2009 | 19577987 |
| influenza vaccination among adults with asthma findings from the 2007 brfss survey. | asthma prevalence among u.s. adults is estimated to be 6.7%. people with asthma are at increased risk of complications from influenza. influenza vaccination of adults and children with asthma is recommended by the advisory committee on immunization practices. the healthy people 2010 objectives call for annual influenza vaccination of at least 60% of adults aged 18-64 years with asthma and other conditions associated with an increased risk of complications from influenza. | 2009 | 19589448 |
| evaluation of four cell lines for assay of infectious adenoviruses in water samples. | human viral contamination in drinking and recreational waters poses health risks. the application of pcr-based molecular technology has advanced our knowledge of the occurrence and prevalence of human viruses in water; however, it has provided no information on viral viability and infectivity. four human cell lines were compared for their sensitivity to different serotypes of human adenoviruses using the tcid50 test. the sensitivity of each cell line varied with different serotypes of adenovirus ... | 2009 | 19590132 |
| imported human rabies--california, 2008. | compared with rabies in developing countries, human rabies is rare in the united states, but animal rabies is common. in the united states, most human rabies cases are associated with rabid bats, whereas in developing countries, dogs are the most common reservoir and vector species. in march 2008, a case of imported human rabies in a recently arrived, undocumented mexican immigrant was laboratory confirmed by public health officials in california. the rabies virus isolated from the patient was a ... | 2009 | 19590490 |
| increased hemoglobin associated with vegf inhibitors in advanced renal cell carcinoma. | we retrospectively analyzed whether increased hemoglobin is a surrogate biomarker of efficacy for vascular endothelial growth factor (vegf) inhibitors in advanced renal cell carcinoma (rcc) patients. twelve patients were identified who had received bevacizumab alone or as combination therapy. eleven patients experienced a rise in hemoglobin. median change was 1.6 g/dl (0-4.0). degree of peak increase correlated with longer progression-free survival (pfs) in metastatic patients: increase of < 15% ... | 2009 | 19603304 |
| influenza vaccination and mortality: differentiating vaccine effects from bias. | it is widely believed that influenza (flu) vaccination of the elderly reduces all-cause mortality, yet randomized trials for assessing vaccine effectiveness are not feasible and the observational research has been controversial. efforts to differentiate vaccine effectiveness from selection bias have been problematic. the authors examined mortality before, during, and after 9 flu seasons in relation to time-varying vaccination status in an elderly california population in which 115,823 deaths occ ... | 2009 | 19625341 |
| tumor marker phenotype concordance in second primary breast cancer, california, 1999-2004. | breast cancer is the most common cancer among women. it is estimated that 7% of women who have breast cancer will develop a subsequent second independent breast tumor within 10 years of the first. the status of estrogen (er), progesterone (pr) and human growth hormone (her2) receptors, individually and as phenotypic combinations, impacts the clinical course of breast cancer and may impact the course of subsequent primary tumors and patient survival. our aims were to determine tumor marker phenot ... | 2010 | 19629680 |
| beyond the "model minority" stereotype: trends in health risk behaviors among asian/pacific islander high school students. | asian/pacific islander (api) students have been stereotyped as the "model minority." the objective of this study was to examine the trends in health risk behaviors among api students who participated in the san diego city schools youth risk behavior survey (yrbs) between 1993 and 2005. | 2009 | 19630868 |
| using behavioral economics to promote physical activity. | behavioral economics is a relatively new field of economics that uses experimental techniques to produce insights about human decision-making. one of its key findings is that people's preferences for actions are not absolute, but rather relative to some anchor point, and can therefore be influenced by changing the anchor. anchor points can be social norms, habits acquired in childhood, or a cultural frame-whether physical activity is presented as fun or as drudgery. physical activity promotion c ... | 2009 | 19632266 |
| genetic variation in cyp17a1 and pancreatic cancer in a population-based case-control study in the san francisco bay area, california. | pancreatic cancer is the fourth leading cause of cancer-related death in men and women in the united states. reproductive factors and steroid hormones have been suspected risk factors for many years, but the results from epidemiologic studies to date have been inconclusive. cyp17a1 encodes cytochrome p450c17alpha, an enzyme with 17alpha-hydroxylase and 17,20-lyase activities in estradiol biosynthesis. a polymorphism in the 5'utr promoter region of cyp17a1-34t/c(a1/a2) has been associated with ci ... | 2010 | 19642097 |
| sporotrichosis: a retrospective evaluation of 23 cases seen in northern california (1987-2007). | sporotrichosis is an uncommon to rare cutaneous and subcutaneous mycosis of animals and humans caused by the dimorphic fungus sporothrix schenckii. twenty-three mammalian cases of sporotrichosis examined between 1987 and 2007 at the university of california, davis - veterinary medical teaching hospital, were retrospectively evaluated with regard to the historical, clinical, diagnostic and treatment findings. cats were the most common species affected (n = 14). in addition, sporotrichosis was dia ... | 2009 | 19659536 |