Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| effects of phonophoresis with arnica montana onto acute inflammatory process in rat skeletal muscles: an experimental study. | this study aimed at verifying the effects of phonophoresis associated with arnica montana on the acute phase of an inflammatory muscle lesion. forty wistar male rats (300+/-50 g), of which the tibialis anterior muscle was surgically lesioned, were divided into four groups (n=10 each): control group received no treatment; the ultrasound group (us) was treated in pulsed mode with 1-mhz frequency, 0.5 w/cm(2) intensity (spatial and temporal average - sata), duty cycle of 1:2 (2 ms on, 4 ms off, 50% ... | 2009 | 19152953 |
| temperature is the key to altitudinal variation of phenolics in arnica montana l. cv. arbo. | plants in alpine habitats are exposed to many environmental stresses, in particular temperature and radiation extremes. recent field experiments on arnica montana l. cv. arbo indicated pronounced altitudinal variation in plant phenolics. ortho-diphenolics increased with altitude compared to other phenolic compounds, resulting in an increase in antioxidative capacity of the tissues involved. factors causing these variations were investigated by climate chamber (cc) experiments focusing on tempera ... | 2009 | 19194724 |
| sesquiterpene lactones in arnica montana: helenalin and dihydrohelenalin chemotypes in spain. | an analytical rplc method for sesquiterpene lactones in arnica montana has been extended to include quantitative analyses of dihydrohelenalin esters. lc-esi-ms-ms distinguished the isomeric helenalin and dihydrohelenalin esters. the dihydrohelenalin esters have lower response factors for uv detection than do helenalin esters, which must be taken into account for quantitative analyses. analyses of flowers from 16 different wild populations of a. montana in spain showed differing proportions of he ... | 2009 | 19235681 |
| perioperative risks and benefits of herbal supplements in aesthetic surgery. | most medications, herbal preparations, and nutraceutical supplements have notable effects on biochemical pathways and may influence wound healing, coagulation, and cardiovascular function. they can also interact with other drugs. a large portion of the data available regarding the effects of naturopathic medicines is anecdotal. marketing of certain products may be misleading and potentially harmful, and quality control standards are highly variable. in order to ensure quality control and standar ... | 2016 | 19371848 |
| remedies containing asteraceae extracts: a prospective observational study of prescribing patterns and adverse drug reactions in german primary care. | the use of complementary therapies by patients has increased over the past 20 years, both in terms of self-medication and physician prescriptions. among herbal medicines, those containing extracts of asteraceae (compositae), such as echinacea spp., arnica montana, matricaria recutita and calendula officinalis, are especially popular in the primary-care setting. however, there remains a gap between the growing acceptance of these remedies and the lack of data on their safety. | 2009 | 19591533 |
| helenalin suppresses essential immune functions of activated cd4+ t cells by multiple mechanisms. | helenalin is a naturally occuring sesquiterpene lactone extracted from arnica montana and arnica chamissonis ssp. foliosa. helenalin and its derivatives are known for anti-cancer and anti-inflammatory effects via inhibiting nf-kappab and telomerase activity and impairing protein and dna synthesis, suggesting that helenalin is a potential candidate for the treatment of deregulated and unwanted t cell-mediated immune responses. here we show that helenalin induces apoptosis in activated cd4+ t cell ... | 2009 | 19656571 |
| evaluation of inhibitory activities of plant extracts on production of lps-stimulated pro-inflammatory mediators in j774 murine macrophages. | whole plant methanolic extracts of 14 traditionally used medicinal herbs were evaluated for their anti-inflammatory activity. extracts of grindelia robusta, salix nigra, arnica montana, and quassia amara showed up to 4.5-fold inhibition of nitric oxide (no) production in the j774 murine macrophage cells challenged with lps without cytotoxicity. these four selected extracts significantly reduced the protein levels of inducible no synthase (inos) and the cyclooxygenase-2 (cox-2) as observed by wes ... | 2010 | 19813079 |
| optimization of culture conditions of arnica montana l.: effects of mycorrhizal fungi and competing plants. | arnica montana is a rare plant that needs special protection because of its intensive harvesting for medicinal purposes. the present work was aimed at finding optimal culture conditions for arnica plants in order to enable their successful reintroduction into their natural stands. plants were cultivated under controlled greenhouse conditions on substrata with different nitrogen (n) concentration. as arnica is always colonized by arbuscular mycorrhizal fungi (amf) in nature, a fact that has been ... | 2010 | 19838743 |
| variation of sesquiterpene lactone contents in different arnica montana populations: influence of ecological parameters. | in ten grassland or heathland sites along a geographic (north to south) and climatic gradient in germany, flowerheads of arnica montana were collected, and the total content of sesquiterpene lactones (sls) as well as the content of the detected single compounds were determined. the ratios of helenalin (h)- and corresponding 11 alpha,13-dihydrohelenalin(dh)-type compounds were calculated. all habitats were characterised concerning the climatic and soil conditions, and the values obtained were cor ... | 2010 | 20101561 |
| arbuscular mycorrhiza of arnica montana under field conditions--conventional and molecular studies. | two distinct populations of arnica montana, an endangered medicinal plant, were studied under field conditions. the material was investigated using microscopic and molecular methods. the analyzed plants were always found to be mycorrhizal. nineteen arbuscular mycorrhizal fungal dna sequences were obtained from the roots. they were related to glomus group a, but most did not match any known species. some showed a degree of similarity to fungi colonizing liverworts. conventional analysis of spores ... | 2010 | 20195874 |
| no effect of a homoeopathic combination of arnica montana and bryonia alba on bleeding, inflammation, and ischaemia after aortic valve surgery. | " arnica montana is a popular homoeopathic treatment with potential haemostatic and anti-inflammatory properties. a homoeopathic combination of a. montana and bryonia alba was used in aortic valve surgery to evaluate its effectiveness in reducing bleeding, inflammation, pain and myocardial ischaemia. | 2010 | 20233176 |
| evaluation of homeopathic arnica montana for ecchymosis after upper blepharoplasty: a placebo-controlled, randomized, double-blind study. | ecchymosis is commonly encountered after upper eyelid blepharoplasty. the use of homeopathic preparations of arnica montana, a flowering herb, has been advocated by physicians, patients, and manufacturers for reduction of postsurgical ecchymosis. the authors evaluate its efficacy after upper eyelid blepharoplasty. | 2010 | 20683279 |
| the effect of topical arnica on muscle pain. | the herb arnica montana, in topical formulations, has been reputed to decrease bruising and muscle pain. this claim has been inadequately and incompletely addressed. | 2010 | 20807867 |
| quantitative analysis of sesquiterpene lactones in extract of arnica montana l. by 1h nmr spectroscopy. | (1)h nmr spectroscopy was used as a method for quantitative analysis of sesquiterpene lactones present in a crude lactone fraction isolated from arnica montana. eight main components - tigloyl-, methacryloyl-, isobutyryl- and 2-methylbutyryl-esters of helenalin (h) and 11α,13-dihydrohelenalin (dh) were identified in the studied sample. the method allows the determination of the total amount of sesquiterpene lactones and the quantity of both type helenalin and 11α,13-dihydrohelenalin esters separ ... | 2011 | 20837387 |
| the effect of polyphenolic-polysaccharide conjugates from selected medicinal plants of asteraceae family on the peroxynitrite-induced changes in blood platelet proteins. | lots of plants belonging to asteraceae family are very popular in folk medicine in poland. these plants are also known as being rich in acidic polysaccharides, due to the presence of hexuronic acids or its derivatives. our preliminary experiments have shown that the extract from conyza canadensis l. possesses various biological activity, including antiplatelet, antiocoagulant and antioxidant properties. the aim of our study was to assess if macromolecular glycoconjugates from selected herbal pla ... | 2010 | 20869393 |
| inflammatory process modulation by homeopathic arnica montana 6ch: the role of individual variation. | the effects of arnica montana 6ch on the individual modulation of acute inflammation kinetics in rats were evaluated. adult male wistar rats were inoculated with 1% carrageenan into the footpad and treated with arnica montana 6ch, dexamethasone (4.0?mg/kg; positive control) or 5% hydroalcoholic solution (negative control), per os, each 15 minutes, between 30 and 180 minutes after the irritant inoculation. histopathological and immunohistochemistry procedures were done in order to get a panel of ... | 2011 | 21318109 |
| identification and characterization of two new derivatives of chlorogenic acids in arnica (arnica montana l.) flowers by high-performance liquid chromatography/tandem mass spectrometry. | arnica montana is a medicinally important plant due to its broad health effects, and it is used in ayurvedic, homeopathic, unani, and folk medicines. we have used lc-ms(n) (n = 2-5) to detect and characterize in arnica flowers 11 quantitatively minor fumaric and methoxyoxalic acid-containing chlorogenic acids, nine of them not previously reported in nature. these comprise 1,5-dicaffeoyl-3-methoxyoxaloylquinic acid, 1,3-dicaffeoyl-4-methoxyoxaloylquinic acid, 3,5-dicaffeoyl-4-methoxyoxaloylquinic ... | 2011 | 21413809 |
| determination of the hydroxycinnamate profile of 12 members of the asteraceae family. | the hydroxycinnamates of the leaves of 12 plants of the astreraceae family, achillea millefolium, arnica montana, artemesia dracunculus, cichorium intybus, cnicus benedictus, cynara scolymus, echinops humilis, inula helenium, lactuca sativa, petasites hybridus, solidago virgaurea, and tanacetum parthenium were investigated qualitatively by lc-ms(n). thirty-nine chlorogenic acids were detected and all characterized to regioisomeric level on the basis of their fragmentation pattern in the tandem m ... | 2011 | 21453943 |
| in vitro antimicrobial activity of romanian medicinal plants hydroalcoholic extracts on planktonic and adhered cells. | the aim of this study was to assess the antibacterial and antifungal potential of some romanian medicinal plants, arnica--arnica montana, wormwood--artemisia absinthium and nettle--urtica dioica. in order to perform this antimicrobial screening, we obtained the vegetal extracts and we tested them on a series of gram-positive and gram-negative bacteria, and also against two fungal strains. the vegetal extracts showed antimicrobial activity preferentially directed against the planktonic fungal and ... | 2011 | 21717806 |
| potential of the homeopathic remedy, arnica montana 30c, to reduce dna damage in escherichia coli exposed to ultraviolet irradiation through up-regulation of nucleotide excision repair genes. | to examine to what degree an ultra-highly diluted homeopathic remedy, arnica montana 30c (am-30c), used in the treatment of shock and injury, can modulate the expression of nucleotide excision repair genes in escherichia coli exposed to ultraviolet (uv) irradiation. | 2012 | 22409925 |
| a homeopathic remedy from arnica, marigold, st. john's wort and comfrey accelerates in vitro wound scratch closure of nih 3t3 fibroblasts. | drugs of plant origin such as arnica montana, calendula officinalis or hypericum perforatum have been frequently used to promote wound healing. while their effect on wound healing using preparations at pharmacological concentrations was supported by several in vitro and clinical studies, investigations of herbal homeopathic remedies on wound healing process are rare. the objective of this study was to investigate the effect of a commercial low potency homeopathic remedy similasan® arnica plus sp ... | 2012 | 22809174 |
| effects of microcurrent application alone or in combination with topical hypericum perforatum l. and arnica montana l. on surgically induced wound healing in wistar rats. | this study evaluated the wound healing activity of microcurrent application alone or in combination with topical hypericum perforatum l. and arnica montana l. on skin surgical incision surgically induced on the back of wistar rats. | 2012 | 22818231 |
| efficacy of a non-hormonal treatment, brn-01, on menopausal hot flashes: a multicenter, randomized, double-blind, placebo-controlled trial. | homeopathic medicines have a place among the non-hormonal therapies for the treatment of hot flashes during the menopause. | 2012 | 22852580 |
| árnica: a multivariate analysis of the botany and ethnopharmacology of a medicinal plant complex in the iberian peninsula and the balearic islands. | medicinal plant complexes of different species sharing vernacular names, morphological and aromatic characteristics and uses are common in traditional medicine of different cultures. a quantitative methodology as a tool for ethnopharmacological studies is presented for systematically analyzing morphological and therapeutic features shared by several species integrating such complexes. | 2012 | 22947388 |
| evaluation of antioxidant and cytoprotective activities of arnica montana l. and artemisia absinthium l. ethanolic extracts. | arnica montana l. and artemisia absinthium l. (asteraceae) are medicinal plants native to temperate regions of europe, including romania, traditionally used for treatment of skin wounds, bruises and contusions. in the present study, a. montana and a. absinthium ethanolic extracts were evaluated for their chemical composition, antioxidant activity and protective effect against h2o2-induced oxidative stress in a mouse fibroblast-like nctc cell line. | 2012 | 22958433 |
| quality control of saffron (crocus sativus l.): development of scar markers for the detection of plant adulterants used as bulking agents. | a method based on sequence-characterized amplified regions (scars) was developed from random amplified polymorphic dna markers (rapds) specific for arnica montana l., bixa orellana l., calendula officinalis l., carthamus tinctorius l., crocus vernus l. (hill), curcuma longa l., and hemerocallis sp. to detect these common bulking agents in commercial saffron (crocus sativus). the method enabled the unequivocal detection of low amounts (up to 1%) of each adulterant, allowing the preemptive rejecti ... | 2012 | 22989071 |
| a systematic review and meta-analysis on the use of hypericum perforatum (st. john's wort) for pain conditions in dental practice. | hypericum perforatum (st. john's wort) has been used for a variety of medicinal indications. most recent research has focussed on its use in herbal form for depression, but its claimed analgesic and anti-inflammatory properties in homeopathic form have also led to a number of studies in patients with acute pain conditions. this systematic review overviews the literature on the use of st. john's wort for pain conditions in homeopathic dental practice. | 2012 | 23089215 |
| traditional knowledge on medicinal and food plants used in val san giacomo (sondrio, italy)--an alpine ethnobotanical study. | this work increases the ethnobotanical data from northern italy and, in particular, the lombardy region, till now poorly documented, safeguarding the local folk knowledge, and provides information on new or scarcely reported properties of medicinal plants, whose traditional use needs to be validated experimentally. | 2013 | 23220197 |
| effect of the oral administration homeopathic arnica montana on mitochondrial oxidative stress. | to analyze the effect of homeopathic arnica on mitochondrial oxidative stress induced by ca(2+) plus inorganic phosphate and/or fe(2+)-citrate-mediated lipid peroxidation through changes in oxygen consumption rates. | 2013 | 23290879 |
| quantification of sesquiterpene lactones in asteraceae plant extracts: evaluation of their allergenic potential. | sesquiterpene lactones (sls), mainly those with an activated exocyclic methylene group, are important allergens in asteraceae (compositae) plants. as a screening tool, the compositae mix, consisting of five asteraceae plant extracts with allergenic potential (feverfew, tansy, arnica, yarrow, and german chamomile) is part of several national patch test baseline series. however, the sl content of the compositae mix may vary due to the source material. therefore, a simple spectrophotometric method ... | 2017 | 24106675 |
| a homeopathic arnica patch for the relief of cellulitis-derived pain and numbness in the hand. | arnica montana, belonging to the compositae family, is a plant with a longstanding tradition of relieving pain and/or inflammation in muscles and joints and may thus represent an alternative to nonsteroidal antiinflammatory drugs, which are often ineffective or lead to a number of adverse effects. a homeopathic arnica patch (3x dilution according to the homeopathic pharmacopoeia of the united states) was developed to alleviate pain symptoms in the back and neck muscles and joints. | 2012 | 24278813 |
| propagation and introduction of arnica montana l. into cultivation: a step to reduce the pressure on endangered and high-valued medicinal plant species. | arnica montana (l.) is an endangered and endemic medicinal plant species in europe. the pressure on natural sources of this plant is alleviated by a suitable use of arnica resources in the european region and introduction into cultivation. the objective of this study was to describe the impact of different ways of plant propagation and introduction on the growth and reproduction mode of this species. during the six consecutive years of the field experiment, the vegetative and reproductive traits ... | 2013 | 24282381 |
| practice patterns in the perioperative treatment of patients undergoing septorhinoplasty: a survey of facial plastic surgeons. | importance the common practices used in the perioperative care of patients undergoing septorhinoplasty are diverse and controversial. a consensus statement on the preferred clinical pathway in the perioperative treatment of patients undergoing septorhinoplasty has yet to be approached formally. objectives to investigate the perioperative treatment of patients undergoing septorhinoplasty and to identify common practice patterns based on the preferences of leading facial plastic surgeons. design, ... | 2015 | 24311187 |
| inhibitory effects of β-cyclodextrin-helenalin complexes on h-tert gene expression in the t47d breast cancer cell line - results of real time quantitative pcr. | nowadays, the encapsulation of cytotoxic chemotherapeutic agents is attracting interest as a method for drug delivery. we hypothesized that the efficiency of helenalin might be maximized by encapsulation in β-cyclodextrin nanoparticles. helenalin, with a hydrophobic structure obtained from flowers of arnica chamissonis and arnica montana, has anti-cancer and anti-inflammatory activity but low water solubility and bioavailability. β-cyclodextrin (β-cd) is a cyclic oligosaccharide comprising seven ... | 2013 | 24377631 |
| differences in the chemical composition of arnica montana flowers from wild populations of north italy. | the flower heads of fourteen wild arnica montana l. populations were collected in the summer of 2010 in the provinces of trento, brescia and bergamo (italy). the dried flowers were analyzed to assess their chemical diversity. hlpc-ms analysis led to the identification of phenolic derivatives and sesquiterpene lactones in the samples, confirming literature data. quali-quantitative analysis of the flower heads showed similar qualitative patterns both for the phenolic as well as sesquiterpene lacto ... | 2014 | 24660447 |
| comparison of cytotoxic and anti-platelet activities of polyphenolic extracts from arnica montana flowers and juglans regia husks. | polyphenolic compounds of plant origin are well known to be beneficial to human health: they exert protective effects on haemostasis and have a particular influence on blood platelets. however, the anti-platelet properties of polyphenolic compounds observed so far have not been weighed against their potential cytotoxic action against platelets. the aim of this study was to demonstrate that anti-platelet and cytotoxic effects on blood platelets may interfere and therefore, may often lead to confu ... | 2015 | 24679412 |
| dental practice scenario in a government homeopathic hospital in west bengal, india. | this pilot investigation initiated a research-targeted systematic dental homeopathy data collection in the dental outpatient section in a government homeopathic hospital in west bengal, india. one conventionally trained dentist and 3 homeopathic doctors collected data from 949 appointments of 411 patients over 3 months. a specifically designed excel spreadsheet enabled recording of consecutive dental appointments that was subjected to data synthesis and analysis in the end. a total of 87.3% cond ... | 2014 | 24742607 |
| characterization and pharmacodynamic properties of arnica montana complex. | a dark brown polymeric complex was isolated from flowering parts of medicinal plant arnica montana l. by hot alkaline extraction followed by neutralization and multi-step extractions with organic solvents. it was recovered in 5.7% yield, on gpc showed two peaks of molecular mass of 9 and 3.5kda. the compositional analyses of arnica complex revealed the presence of carbohydrates (26%), uronic acids (12%), phenolics (1.25mm or 213mg of gae/1g), and low protein content (∼1%). the carbohydrate moiet ... | 2014 | 24875316 |
| ethnobotanical and phytomedical knowledge in the north-western ligurian alps. | the ethnobotany of european alpine regions is much diversified and scarcely investigated. these regions retain a well-developed heritage culture and botanical traditional knowledge, favored by the isolated montane location. we carried out a study of therapeutic and traditional uses of native plants of a poorly explored area of the western italian alps in the ligurian region (nw italy). the area has been the object of human activities since prehistoric ages, and an obliged crossroad for people mo ... | 2014 | 24910407 |
| a sensitive sensor cell line for the detection of oxidative stress responses in cultured human keratinocytes. | in the progress of allergic and irritant contact dermatitis, chemicals that cause the generation of reactive oxygen species trigger a heat shock response in keratinocytes. in this study, an optical sensor cell line based on cultured human keratinocytes (hacat cells) expressing green fluorescent protein (gfp) under the control of the stress-inducible hsp70b' promoter were constructed. exposure of hacat sensor cells to 25 µm cadmium, a model substance for oxidative stress induction, provoked a 1.7 ... | 2014 | 24967604 |
| effectiveness and safety of arnica montana in post-surgical setting, pain and inflammation. | arnica montana has been widely used as a homeopathic remedy for the treatment of several inflammatory conditions in pain management and postoperative settings. this review gives an overview of the therapeutic use of arnica montana in the above-mentioned fields also focusing on its mechanisms of action learned from animal models and in vitro studies. arnica montana is more effective than placebo when used for the treatment of several conditions including post-traumatic and postoperative pain, ede ... | 2016 | 25171757 |
| core-hom: a powerful and exhaustive database of clinical trials in homeopathy. | the core-hom database was created to answer the need for a reliable and publicly available source of information in the field of clinical research in homeopathy. as of may 2014 it held 1048 entries of clinical trials, observational studies and surveys in the field of homeopathy, including second publications and re-analyses. 352 of the trials referenced in the database were published in peer reviewed journals, 198 of which were randomised controlled trials. the most often used remedies were arni ... | 2014 | 25439037 |
| fourteen polymorphic microsatellite markers for the threatened arnica montana (asteraceae). | 2015 | 25606354 | |
| plants with topical uses in the ripollès district (pyrenees, catalonia, iberian peninsula): ethnobotanical survey and pharmacological validation in the literature. | the skin is the main structure that protects the human body from environmental factors and has, in addition, a relevant relationship to people׳s appearance and beauty. official medicine and cosmetics have shown interest on elaborating products to protect the dermal system, yet the role of folk medicine is highly unknown in this field. taking this into account, we performed an ethnobotanical study in a catalan district of the eastern pyrenees (northeast iberian peninsula), with the purpose of ass ... | 2015 | 25666424 |
| identification of hsp70-inducing activity in arnica montana extract and purification and characterization of hsp70-inducers. | the expression of heat shock proteins (hsps), particularly hsp70, is receiving considerable attention in the field of cosmetics, particularly given our recent report that ultraviolet-induced melanin production, skin damage and wrinkle formation were all suppressed in transgenic mice expressing hsp70. | 2015 | 25724362 |
| perioperative arnica montana for reduction of ecchymosis in rhinoplasty surgery. | studies of homeopathic therapies to decrease postrhinoplasty ecchymosis have previously used subjective measurements, limiting their clinical significance. recently, arnica montana was shown to decrease postoperative ecchymosis after rhytidectomy, using an objective measuring tool. we believe that oral a. montana, given perioperatively, can be objectively shown to reduce extent and intensity of postoperative ecchymosis in rhinoplasty surgery. | 2016 | 25954844 |
| cumulative therapeutic effects of phytochemicals in arnica montana flower extract alleviated collagen-induced arthritis: inhibition of both pro-inflammatory mediators and oxidative stress. | the plant arnica montana is used in folk medicine to alleviate pain, inflammation and swelling of muscles and joints associated with rheumatoid arthritis and other inflammatory conditions. the present study aimed to investigate the therapeutic effects and mechanism of action of a. montana flower methanol extract (amme) against both inflammation and oxidative stress in a collagen-induced arthritis (cia) rat model. | 2016 | 25966322 |
| endophytic streptomyces in the traditional medicinal plant arnica montana l.: secondary metabolites and biological activity. | arnica montana l. is a medical plant of the asteraceae family and grows preferably on nutrient poor soils in mountainous environments. such surroundings are known to make plants dependent on symbiosis with other organisms. up to now only arbuscular mycorrhizal fungi were found to act as endophytic symbiosis partners for a. montana. here we identified five streptomyces strains, microorganisms also known to occur as endophytes in plants and to produce a huge variety of active secondary metabolites ... | 2015 | 26036671 |
| physiotherapy and a homeopathic complex for chronic low-back pain due to osteoarthritis: a randomized, controlled pilot study. | osteoarthritis (oa) is a common cause of chronic low-back pain (clbp) and can be managed with drug therapy and physiotherapy. homeopathic remedies may assist managing oa; however, research that supports their effectiveness is limited. | 2016 | 26773321 |
| assessing the effectiveness of arnica montana and rhododendron tomentosum (ledum palustre) in the reduction of ecchymosis and edema after oculofacial surgery: preliminary results. | the purpose of this study was to provide preliminary data on the potential effectiveness of the combination of topical arnica montana and rhododendron tomentosum (ledum palustre) in reducing postoperative ecchymosis and edema in a select population of healthy volunteers after oculofacial surgery. | 2017 | 26863038 |
| chemometrics-based approach in analysis of arnicae flos. | arnica montana flowers have a long history as herbal medicines for external use on injuries and rheumatic complaints. | 2015 | 27013791 |
| arnica montana effects on gene expression in a human macrophage cell line. evaluation by quantitative real-time pcr. | arnica montana is a popular traditional remedy widely used in complementary medicine, also for its wound healing properties. despite its acknowledged action in clinical settings at various doses, the molecular aspects relating to how a. montana promotes wound healing remain to be elucidated. to fill this gap, we evaluated the whole plant extract, in a wide range of dilutions, in thp-1 human cells, differentiated into mature macrophages and into an alternative il-4-activated phenotype involved in ... | 2016 | 27211321 |
| developmental and environmental effects on sesquiterpene lactones in cultivated arnica montana l. | the amount of sesquiterpene lactones and the lactone profile of arnica montana l. in flowering and seed formation stages in vitro and in vivo propagated from seeds of german, ukrainian, and austrian origin and grown in two experimental fields were studied. it was found that in vitro propagated 2-year plants in full flowering stage accumulated higher amount of lactones in comparison to in vivo propagated 3-year plants and to the seed formation stage, respectively. helenalins predominated in in vi ... | 2016 | 27368426 |
| genetic structure of colline and montane populations of an endangered plant species. | due to land-use intensification, lowland and colline populations of many plants of nutrient-poor grasslands have been strongly fragmented in the last decades, with potentially negative consequences for their genetic diversity and persistence. populations in mountains might represent a genetic reservoir for grassland plants, because they have been less affected by land-use changes. we studied the genetic structure and diversity of colline and montane vosges populations of the threatened perennial ... | 2016 | 27519913 |
| commentary: arnica montana effects on gene expression in a human macrophage cell line: evaluation by quantitative real-time pcr. | 2016 | 27660630 | |
| response to commentary: arnica montana effects on gene expression in a human macrophage cell line. evaluation by quantitative real-time pcr. | 2016 | 27667990 | |
| arnica montana stimulates extracellular matrix gene expression in a macrophage cell line differentiated to wound-healing phenotype. | arnica montana (arnica m.) is used for its purported anti-inflammatory and tissue healing actions after trauma, bruises, or tissue injuries, but its cellular and molecular mechanisms are largely unknown. this work tested arnica m. effects on gene expression using an in vitro model of macrophages polarized towards a "wound-healing" phenotype. the monocyte-macrophage human thp-1 cell line was cultured and differentiated with phorbol-myristate acetate and interleukin-4, then exposed for 24h to arni ... | 2016 | 27832158 |
| re: "assessing the effectiveness of arnica montana and rhododendron tomentosum (ledum palustre) in the reduction of ecchymosis and edema after oculofacial surgery: preliminary results". | 2017 | 28060247 | |
| reply re: "assessing the efficacy of arnica montana and rhododendron tomentosum (ledum palustre) in the reduction of ecchymosis and edema after oculofacial surgery: preliminary results". | 2017 | 28060248 | |
| feasibility, acceptability, and tolerability of rgn107 in the palliative wound care management of chronic wound symptoms. | to assess the feasibility, acceptability and tolerability of rgn107 use, a natural powder blend of arnica montana, calendula officinalis, mentha arvensis and santalum album, among hospice patients and their wound caregivers in the palliative wound care management of chronic wound symptoms at end-of-life. | 2017 | 28105900 |
| is there a role for homeopathy in breast cancer surgery? a first randomized clinical trial on treatment with arnica montana to reduce post-operative seroma and bleeding in patients undergoing total mastectomy. | this study aimed to evaluate the benefits of arnica montana on post-operative blood loss and seroma production in women undergoing unilateral total mastectomy by administering arnica montana 1000 korsakovian dilution (1000 k). | 2017 | 28163953 |
| phytomedicine in joint disorders. | chronic joint inflammatory disorders such as osteoarthritis and rheumatoid arthritis have in common an upsurge of inflammation, and oxidative stress, resulting in progressive histological alterations and disabling symptoms. currently used conventional medication (ranging from pain-killers to biological agents) is potent, but frequently associated with serious, even life-threatening side effects. used for millennia in traditional herbalism, medicinal plants are a promising alternative, with lower ... | 2017 | 28275210 |