Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| [pyoderma in dogs]. | bacterial infections associated with cutaneous commensal organisms like staphylococcus pseudintermedius are frequently encountered in small animal practice. in this review, pathogenesis, clinical signs, and topical and systemic therapeutic options are discussed. | 2011 | 22167166 |
| Bactericidal properties of pradofloxacin against veterinary pathogens. | Pradofloxacin is a new veterinary 8-cyano-fluoroquinolone developed for use against bacterial infections in dogs and cats involving both aerobic and anaerobic bacteria. The minimal bactericidal concentrations have been determined against clinical isolates of Staphylococcus pseudintermedius, Staphylococcus aureus, Escherichia coli, Pasteurella multocida, Streptococcus canis, Proteus spp., Fusobacterium spp., Porphyromonas gingivalis and Prevotella species. A subset of these species was selected, ... | 2011 | 22209121 |
| methicillin-resistant staphylococcus pseudintermedius isolated from canine pyoderma in north china. | aims: to determine the prevalence of carriage of methicillin-resistant staphylococcus pseudintermedius (mrsp) among dogs with pyoderma from two small animal hospitals in north china during a 21-month period, and to characterize these isolates. methods and results: swabs were taken from 260 dogs with pyoderma, the staphylococcal species isolated and methicillin resistance were confirmed phenotypically and genotypically. the identified mrsp isolates were characterized by multilocus sequence typi ... | 2012 | 22229826 |
| what's happened to staphylococcus intermedius? taxonomic revision and emergence of multi-drug resistance. | staphylococcus intermedius has been the predominant coagulase-positive staphylococcus isolated from canine skin and mucosae and the most commonly reported staphylococcal pathogen in small animal practice for the last 35 years. although microbiological tests have historically indicated variability in biochemical characteristics amongst s. intermedius isolates from animals, an acceptable level of diagnostic accuracy for clinical purposes was readily achievable with routine phenotypic testing. howe ... | 2012 | 22251285 |
| distribution of sccmec-associated phenol-soluble modulin in staphylococci. | the recently described phenol-soluble modulin psm-mec was detected in staphylococcus aureus, staphylococcus epidermidis, staphylococcus fleuretti, staphylococcus hominis, staphylococcus pseudintermedius, staphylococcus saprophyticus, staphylococcus simulans and staphylococcus vitulinus from different hosts (humans, goats, dogs, cats, pigs, cattle and turkeys). it was identified in isolates harbouring sccmec types ii, iia, iib, iid, iii, viii and in some irregular or truncated elements. | 2012 | 22251619 |
| clonal diversity and biofilm-forming ability of methicillin-resistant staphylococcus pseudintermedius. | the aim of this study was to investigate the clonal epidemiology of methicillin-resistant staphylococcus pseudintermedius (mrsp) isolates from dogs in norway and to evaluate the antimicrobial resistance patterns and determine the biofilm-forming abilities of the isolates. | 2012 | 22258925 |
| insertion sequence is256 in canine pyoderma isolates of staphylococcus pseudintermedius associated with antibiotic resistance. | staphylococcus pseudintermedius is the most frequent staphylococcal species isolated from canine pyoderma. the control of s. pseudintermedius infection is often difficult due to the expanded antimicrobial resistance phenotypes. antibiotic resistance in staphylococcal pathogens is often associated to mobile genetic elements such as the insertion sequence is256 that was first described as a part of the transposon tn4001, which confers aminoglycoside resistance in staphylococcus aureus and in staph ... | 2011 | 22261238 |
| activity, expression and genetic variation of canine β-defensin 103: a multifunctional antimicrobial peptide in the skin of domestic dogs. | the skin functions as more than a physical barrier to infection. epithelial cells of the skin can synthesize antimicrobial peptides, including defensins, which exhibit direct antimicrobial activity. here we characterize the expression pattern, genetic variation and activity of the major β-defensin expressed in canine skin, canine β-defensin 103 (cbd103). the gene encoding cbd103 exhibits two forms of polymorphism: a common 3-basepair deletion allele and a gene copy-number variation. golden retri ... | 2012 | 22261569 |
| comparative genomic analysis of the genus staphylococcus including staphylococcus aureus and its newly described sister species staphylococcus simiae. | staphylococcus belongs to the gram-positive low g + c content group of the firmicutes division of bacteria. staphylococcus aureus is an important human and veterinary pathogen that causes a broad spectrum of diseases, and has developed important multidrug resistant forms such as methicillin-resistant s. aureus (mrsa). staphylococcus simiae was isolated from south american squirrel monkeys in 2000, and is a coagulase-negative bacterium, closely related, and possibly the sister group, to s. aureus ... | 2012 | 22272658 |
| comparative activity of pradofloxacin and marbofloxacin against coagulase-positive staphylococci in a pharmacokinetic-pharmacodynamic model based on canine pharmacokinetics. | pradofloxacin (pra), a novel veterinary 8-cyano-fluoroquinolone (fq), is active against staphylococcus pseudintermedius, the primary cause of canine pyoderma. an in vitro pharmacokinetic-pharmacodynamic model was used to compare the activities of pra and marbofloxacin (mar) against three clinical isolates of s. pseudintermedius and reference strain staphylococcus aureus atcc 6538. experiments were performed involving populations of 10(10) cfu corresponding to an inoculum density of approximately ... | 2012 | 22276681 |
| selection of antibiotics for meticillin-resistant staphylococcus pseudintermedius: time to revisit some old drugs? | the aim of this review is to consider systemic therapy options for meticillin-resistant staphylococcus pseudintermedius (mrsp). infections caused by mrsp in small animals--particularly dogs--have been frustrating veterinarians in recent years. after a susceptibility test is performed, veterinarians are left to select from drugs that have not been frequently encountered on a susceptibility report. some of these are old drugs that have not been used regularly by veterinary dermatologists. as mrsp ... | 2012 | 22313056 |
| treatment outcome of dogs with meticillin-resistant and meticillin-susceptible staphylococcus pseudintermedius pyoderma. | the prevalence of meticillin- and multidrug-resistant staphylococcus pseudintermedius (mrsp) in canine pyoderma has been increasing in recent years; thus, treatment of these cases has become challenging. | 2012 | 22364681 |
| prevalence of meticillin-resistant staphylococcus pseudintermedius (mrsp) from skin and carriage sites of dogs after treatment of their meticillin-resistant or meticillin-sensitive staphylococcal pyoderma. | meticillin-resistant staphylococci are significant pathogens in veterinary dermatology, yet longitudinal studies of the impact of routine antimicrobial therapy on emergence or resolution of resistance are lacking. | 2012 | 22364707 |
| [staphylococcus pseudintermedius and pasteurella dagmatis associated in a case of community-acquired pneumonia]. | 2012 | 22366256 | |
| antibiotic treatments of a methicillin-resistant staphylococcus pseudintermedius infection in a dog: a case presentation. | 2012 | 22378055 | |
| comparative mutant prevention concentration and mechanism of resistance to veterinary fluoroquinolones in staphylococcus pseudintermedius. | the problem of antibacterial drug resistance is increasing worldwide, in part due to the therapeutic concentrations currently used based on the minimal inhibitory concentration (mic) as a measure of potency are often the very concentrations required to selectively enrich the resistant mutant portion of the population. a mutant prevention concentration (mpc)-based dosing strategy is suggested to improve the therapeutic outcome based on the mic. | 2012 | 22409306 |
| in vitro antimicrobial activity of miconazole and polymyxin b against canine meticillin-resistant staphylococcus aureus and meticillin-resistant staphylococcus pseudintermedius isolates. | meticillin-resistant staphylococcus aureus (mrsa) and meticillin-resistant staphylococcus pseudintermedius (mrsp) infections are increasingly reported in dogs, and these bacteria may be isolated from ear infections. | 2012 | 22409321 |
| carriage of methicillin-resistant staphylococcus pseudintermedius in dogs--a longitudinal study. | methicillin-resistant s. pseudintermedius strains (mrsp) are reported with increasing frequency in bacterial cultures from dogs. the objectives of this study were to determine whether mrsp could be found in dogs several months after a clinically apparent infection and whether the length of carriage varied depending on systemic antimicrobial treatment, diagnosis at time of the first positive mrsp culture and the presence of skin disease or wounds. thirty-one dogs previously diagnosed with a clini ... | 2012 | 22444911 |
| recovery of staphylococci from computer keyboards in a veterinary medical centre and the effect of routine cleaning. | computers play a vital role in veterinary clinics for grading, examining results, updating records, giving discharge instructions and maintaining billing information. few studies have documented the degree of contamination or practical methods to disinfect computer equipment within the veterinary clinic setting. the intent of the present study was to characterise the frequency of recovery of staphylococcus species from computer keyboards from a veterinary teaching hospital setting and to evaluat ... | 2012 | 22447457 |
| meticillin-resistant staphylococcus pseudintermedius: clinical challenge and treatment options. | meticillin-resistant staphylococcus pseudintermedius (mrsp) has emerged as a major therapeutic challenge for small animal veterinarians over the past 10 years and continues to spread worryingly in many countries. this review focuses on the clinical aspects of mrsp infections seen in patients with skin disease and on currently available treatment options. in addition, it discusses the implications for in-contact people, other animals and the environment, because infection control strategies are l ... | 2012 | 22486942 |
| staphylococcus pseudintermedius in the dog: taxonomy, diagnostics, ecology, epidemiology and pathogenicity. | the dog is the natural host of staphylococcus pseudintermedius. many research efforts are currently being undertaken to expand our knowledge and understanding of this important canine commensal and opportunistic pathogen. the objective of this review is to summarize the current knowledge of the species, including the latest research outcomes, with emphasis on taxonomy, diagnostics, ecology, epidemiology and pathogenicity. despite the important taxonomic changes that have occurred over the past f ... | 2012 | 22515504 |
| the in vitro activity of 15 antimicrobial agents against bacterial isolates from dogs. | the in vitro activity of 15 antimicrobial agents against clinical isolates of staphylococcus pseudintermedius, staphylococcus aureus, escherichia coli, pasteurella spp. and streptococcus canis from dogs was investigated. for staphylococcus spp., the highest frequency of resistance was observed for penicillin, followed by ampicillin, tetracycline and chloramphenicol. the highest frequency of resistance in e. coli isolates was recorded for tetracycline and streptomycin. pasteurella spp. and s. can ... | 2012 | 22516694 |
| genetic and phenotypic characterization of methicillin-resistant staphylococci isolated from veterinary hospitals in south korea. | staphylococci were isolated from veterinary staff, hospitalized animals, and medical equipment from 2 major tertiary veterinary hospitals in south korea to investigate antimicrobial resistance and genetic relatedness. the detection rate for staphylococci was 55.2% (111/201 samples), and 11 species were identified among the collected staphylococcal strains. the most prevalent species were staphylococcus pseudintermedius (52/111, 46.8%), staphylococcus epidermidis (21/111, 18.9%), and staphylococc ... | 2012 | 22529115 |
| methicillin-resistant staphylococcal contamination of cellular phones of personnel in a veterinary teaching hospital. | hospital-associated infections are an increasing cause of morbidity and mortality in veterinary patients. with the emergence of multi-drug resistant bacteria, these infections can be particularly difficult to eradicate. sources of hospital-associated infections can include the patients own flora, medical staff and inanimate hospital objects. cellular phones are becoming an invaluable feature of communication within hospitals, and since they are frequently handled by healthcare personnel, there m ... | 2012 | 22533923 |
| misuse of antimicrobials and selection of methicillin-resistant staphylococcus pseudintermedius strains in breeding kennels: genetic characterization of bacteria after a two-year interval. | methicillin-resistant staphylococcus pseudintermedius (mrsp) strains have been isolated from dogs with increasing frequency; prolonged or excessive use of antimicrobials is associated with the selection of mrsp, and misuse of antimicrobials is frequent in breeding kennels. this study was carried out in two breeding kennels (a and b) in which we had isolated mrsp in 2008: the aim was to assess colonization of previously positive bitches and of other bitches sharing the same environment and to ass ... | 2013 | 22551469 |
| factors associated with methicillin-resistant versus methicillin-susceptible staphylococcus pseudintermedius infection in dogs. | to compare methicillin-resistant staphylococcus pseudintermedius (mrsp) and methicillin-susceptible s pseudintermedius (mssp) infections in dogs. | 2012 | 22657928 |
| antimicrobial resistance of staphylococcus pseudintermedius. | staphylococcus pseudintermedius, staphylococcus intermedius and staphylococcus delphini together comprise the s. intermedius group (sig). within the sig, s. pseudintermedius represents the major pathogenic species and is involved in a wide variety of infections, mainly in dogs, but to a lesser degree also in other animal species and humans. antimicrobial agents are commonly applied to control s. pseudintermedius infections; however, during recent years s. pseudintermedius isolates have been iden ... | 2012 | 22681522 |
| evidence for production of a bacteriocin-like substance by staphylococcus pseudintermedius, inhibitory to staphylococcus aureus from foods. | this study assessed the production of a bacteriocin-like substance by staphylococcus pseudintermedius s28, and evaluates its inhibitory effect against isolates of s. aureus from foods. all indicator isolates were sensitive to the substance produced from s. pseudintermedius s28, showing growth inhibition zones ranging from 14.2 to 28.3 mm. the inhibitory substance has no effect against the producer strain. the inhibitory substance was affected by proteolytic enzymes, while glycolytic and lipolyti ... | 2013 | 22703567 |
| occurrence of methicillin-resistant staphylococci in surgically treated dogs and the environment in a swedish animal hospital. | to investigate whether hospitalised dogs treated surgically may become culture positive for methicillin-resistant staphylococcus pseudintermedius or methicillin-resistant staphylococcus aureus. | 2012 | 22747733 |
| staphylococcus pseudintermedius colonization patterns and strain diversity in healthy dogs: a cross-sectional and longitudinal study. | this is the first large-scale study of staphylococcus pseudintermedius colonization and diversity in healthy dogs where samples were collected over a long time and strains were identified by pcr according to the current taxonomy of the s. intermedius group and typed by a highly discriminatory method such as pulsed field gel electrophoresis (pfge). a cross-sectional study of nasal, oral, perineal and inguinal carriage in 119 healthy dogs was followed by a longitudinal study where oral and perinea ... | 2012 | 22770516 |
| prevalence and characterization of methicillin-resistant staphylococcus pseudintermedius in pets from south china. | the aim of this study was to determine the presence of and characterize methicillin-resistant staphylococcus pseudintermedius (mrsp) isolated from pets in south china. from 2007 to 2009, 898 samples were collected from 785 pets in guangdong province. the identity of staphylococcal species and the presence of methicillin resistance were confirmed by phenotypic and genotypic assays. the genetic relationships of mrsp isolates were determined by multilocus sequence typing (mlst), pfge and spa typing ... | 2012 | 22770517 |
| evaluation of cefoxitin disk diffusion breakpoint for detection of methicillin resistance in staphylococcus pseudintermedius isolates from dogs. | cefoxitin disk diffusion susceptibility testing is a recommended screening method for the detection of methicillin resistance in human isolates of staphylococcus aureus and coagulase-negative staphylococci. a retrospective analysis of 1,146 clinical isolates of staphylococcus pseudintermedius from dogs was conducted to determine if screening by the cefoxitin disk method can be similarly useful with s. pseudintermedius. the distribution of cefoxitin growth inhibition zone diameters within this co ... | 2012 | 22786971 |
| in vitro miconazole susceptibility of meticillin-resistant staphylococcus pseudintermedius and staphylococcus aureus. | the emergence and dissemination of meticillin-resistant staphylococci has created significant treatment challenges in veterinary medicine and increased interest in topical therapy for superficial infections. concern has been expressed regarding the use of some topical antimicrobials in animals because of the potential for emergence of resistance, and additional options are required. miconazole has limited antibacterial properties that include antistaphylococcal activity. | 2012 | 22830415 |
| case-control study of staphylococcus lugdunensis infection isolates from small companion animals. | coagulase-negative staphylococcus lugdunensis has recently been shown to cause invasive infections of people, which are similar in pathogenic effect to those caused by staphylococcus aureus. little is known about the pathogenicity of s. lugdunensis in companion animals. | 2012 | 22862546 |
| antimicrobial resistance in bacteria from breeding dogs housed in kennels with differing neonatal mortality and use of antibiotics. | this work examines the antimicrobial resistance of potentially pathogenic bacteria (staphylococcus pseudintermedius, streptococcus canis, escherichia coli) found in the vaginal tract in prepartum mammary secretions and postpartum milk of bitches housed in breeding kennels (n = 20; 92 bitches). the kennels were divided into three categories: no routine antimicrobial administration around parturition (category 1); routine administration of one antibiotic around parturition (category 2); routine ad ... | 2012 | 22898018 |
| comparative genomics of the staphylococcus intermedius group of animal pathogens. | the staphylococcus intermedius group consists of three closely related coagulase-positive bacterial species including s. intermedius, staphylococcus pseudintermedius, and staphylococcus delphini. s. pseudintermedius is a major skin pathogen of dogs, which occasionally causes severe zoonotic infections of humans. s. delphini has been isolated from an array of different animals including horses, mink, and pigeons, whereas s. intermedius has been isolated only from pigeons to date. here we provide ... | 2012 | 22919635 |
| methicillin-resistant staphylococcus pseudintermedius in sweden. | staphylococcus pseudintermedius is an opportunistic pathogen that is one of the most frequent causes of infections in dogs. in europe, there are increasing reports of methicillin-resistant s. pseudintermedius (mrsp), and in sweden, mrsp has also been more frequently isolated during recent years. however, there is limited knowledge regarding the epidemiology and genetic relationship among the swedish isolates. this study therefore investigated the genetic relationship of mrsp isolated from compan ... | 2012 | 22931056 |
| multi-resistant staphylococcus pseudintermedius: a wake-up call in our approach to bacterial infection. | 2012 | 22931397 | |
| susceptibility of canine and feline bacterial pathogens to pradofloxacin and comparison with other fluoroquinolones approved for companion animals. | in this study, 908 bacterial pathogens from defined infections of dogs and cats were tested for their susceptibility to the novel fluoroquinolone pradofloxacin, which was approved in 2011 for use in cats and dogs. most of the bacteria tested (staphylococcus aureus, staphylococcus pseudintermedius, escherichia coli, β-haemolytic streptococci, pasteurella multocida and bordetella bronchiseptica) exhibited low pradofloxacin mic(90) values of ≤ 0.25 μg/ml. solely proteus spp. and pseudomonas aerugin ... | 2013 | 22939523 |
| in vitro evaluation of topical biocide and antimicrobial susceptibility of staphylococcus pseudintermedius from dogs. | staphylococcus pseudintermedius is an important canine pathogen, and the emergence and widespread dissemination of meticillin-resistant strains (mrsp) is of significant concern. multidrug-resistant infections may require alternative approaches, such as the use of topical therapy. there is minimal information about the in vitro susceptibility of meticillin-susceptible s. pseudintermedius (mssp) and mrsp to biocides and topical antimicrobials. | 2012 | 23050904 |
| transcription of canine toll-like receptor 2, β-defensin 1 and β-defensin 103 in infected atopic skin, non-infected atopic skin, healthy skin and the cpek cell line. | dogs and humans with atopic dermatitis (ad) have a high prevalence of recurrent staphylococcal pyoderma. β-defensins (bds) and toll-like receptors (tlrs) are important in innate immunity against bacterial skin infections, and decreased bd and tlr2 expression has been associated with human ad. however, findings from recent studies of bd expression in human and canine ad have been variable and contradictory. the aim of this study was to further our understanding of the role of antimicrobial protei ... | 2013 | 23067725 |
| evaluation of minocycline susceptibility of methicillin-resistant staphylococcus pseudintermedius. | methicillin-resistant staphylococcus pseudintermedius (mrsp) is an increasingly important cause of opportunistic infections in dogs and cats. treatment options are often limited because of the high level of antimicrobial resistance. doxycycline resistance is common, but variable mechanisms of doxycycline resistance exist, with some conferring resistance to doxycycline but not minocycline. however, there has been limited study of minocycline susceptibility in clinical mrsp isolates nor has the as ... | 2013 | 23107659 |
| multilocus sequence typing for characterization of staphylococcus pseudintermedius. | staphylococcus pseudintermedius is an opportunistic pathogen in dogs. four housekeeping genes with allelic polymorphisms were identified and used to develop an expanded multilocus sequence typing (mlst) scheme. the new seven-locus technique shows s. pseudintermedius to have greater genetic diversity than previous methods and discriminates more isolates based upon host origin. | 2013 | 23115265 |
| high diversity of staphylococcus aureus and staphylococcus pseudintermedius lineages and toxigenic traits in healthy pet-owning household members. underestimating normal household contact? | forty-three unrelated pet-owning households were screened in spain to study the staphylococcus aureus and staphylococcus pseudintermedius nasal carriage, their genetic lineages and virulence traits. sixty-seven healthy owners and 66 healthy pets were investigated. isolates characterization was performed and potential interspecies transmission was assessed. s. aureus was present in 51.2% of households studied while s. pseudintermedius in 30.2%. twenty-eight owners (41.8%) carried s. aureus: one m ... | 2013 | 23153600 |
| efficacy of clarithromycin on biofilm formation of methicillin-resistant staphylococcus pseudintermedius. | surgical site infections (ssis) caused by biofilm-forming methicillin-resistant staphylococcus pseudintermedius (mrsp) have emerged as the most common hospital-acquired infections in companion animals. no methods currently exist for the therapeutic remediation of ssis caused by mrsp in biofilms. clarithromycin (cla) has been shown to prevent biofilm formation by staphylococcus aureus. this study aims to assess the in vitro activity of cla in eradicating mrsp biofilm formation on various material ... | 2012 | 23171620 |
| feasibility of magnetic resonance electrical impedance tomography (mreit) conductivity imaging to evaluate brain abscess lesion: in vivo canine model. | to show the feasibility of magnetic resonance electrical impedance tomography (mreit) conductivity imaging in terms of its capability to provide new contrast information of abscess lesion and characterize time-course variations before and after the induction of brain abscess. | 2013 | 23239506 |
| methicillin-resistant staphylococcus pseudintermedius in rats. | 2013 | 23260061 | |
| molecular characterization of high-level mupirocin resistance in staphylococcus pseudintermedius. | the genetic analysis of high-level mupirocin resistance (hi-mup(r)) in a staphylococcus pseudintermedius isolate from a dog is presented. the hi-mup(r) iles2 gene flanked by a novel rearrangement of directly repeated insertion sequence is257 elements was located, together with the aminoglycoside resistance aaca-aphd determinant, on a conjugative plasmid related to the psk41/pgo1 family plasmids. | 2012 | 23269741 |
| pathogenicity potential of staphylococcus pseudintermedius strains isolated from canine carriers and from dogs with infection signs. | 2013 | 23328490 | |
| serum anti-staphylococcus pseudintermedius ige and igg antibodies in dogs with atopic dermatitis and nonatopic dogs. | dogs and humans with atopic dermatitis (ad) are predisposed to colonization and recurrent infection with staphylococcus spp. studies in humans suggest that staphylococcus-specific immunoglobulin e (ige) plays a key role in disease pathogenesis. few such studies have been undertaken in dogs. | 2013 | 23331675 |
| in vitro antiseptic susceptibilities for staphylococcus pseudintermedius isolated from canine superficial pyoderma in japan. | topical therapy, particularly with chlorhexidine, is becoming increasingly common as a treatment option for canine pyoderma; however, there are limited studies on the susceptibility of staphylococcus pseudintermedius to chlorhexidine compounds. | 2013 | 23331688 |
| usefulness of cefovecin disk-diffusion test for predicting meca gene-containing strains of staphylococcus pseudintermedius and clinical efficacy of cefovecin in dogs with superficial pyoderma. | cefovecin has been widely used to treat skin infections in dogs. the relationship of the cefovecin disk-diffusion test results to the presence of the meca gene and the clinical efficacy of cefovecin have not been fully evaluated. | 2013 | 23331693 |
| identification and antibiotic susceptibility of bacterial isolates from dogs with otitis externa in australia. | to identify and quantify the five most frequently isolated significant bacterial microorganisms, and their antibiotic susceptibility, from bacterial cultures of samples taken from the ears of dogs with otitis externa. | 2012 | 23356371 |
| residual antibacterial activity of dog hairs after therapy with antimicrobial shampoos. | topical antimicrobial treatment for canine pyoderma is becoming increasingly important, but little is known about the mechanism of action and persistence of activity of antimicrobial shampoos. | 2013 | 23432432 |
| successful treatment of encrusted cystitis associated with staphylococcus pseudintermedius infection in the urinary bladder of a dog. | a 5-year-old female spayed mixed-breed dog was examined because of signs of persistent stranguria following treatment for urethral obstruction. | 2013 | 23445291 |
| methicillin-resistant staphylococcus pseudintermedius infection in a bone marrow transplant recipient. | staphylococcus pseudintermedius is a veterinary pathogen that has seldom been described as an agent of human disease. features of this probably underreported coagulase-positive staphylococcus species are depicted here through the description of a graft-versus-host disease-related wound infection caused by a multidrug-resistant strain. | 2013 | 23486715 |
| genome sequence of staphylococcus pseudintermedius strain e140, an st71 european-associated methicillin-resistant isolate. | we report the first genome sequence of the methicillin-resistant staphylococcus pseudintermedius (mrsp) strain e140, isolated from a canine bite wound infection in denmark. this strain represents the dominant clonal lineage associated with canine mrsp infections in europe. | 2013 | 23516230 |
| characterization of methicillin-resistant staphylococcus pseudintermedius isolated from dogs and cats. | the aim of this study was to explore the presence of methicillin-resistant staphylococcus pseudintermedius (mrsp) in a collection of s. pseudintermedius strains isolated from dogs and cats with dermatitis in japan and to compare their genotypic and phenotypic characteristics. clonal relationships were determined by pulse field gel electrophoresis (pfge), staphylococcal chromosomal cassette mec (sccmec) typing, and multilocus sequence typing (mlst). biofilm formation assay was performed using saf ... | 2013 | 23607810 |
| may staphylococcus pseudintermedius be non-haemolytic? | 2013 | 23618797 | |
| a comparative evaluation of methicillin-resistant staphylococci isolated from harness racing-horses, breeding mares and riding-horses in italy. | to investigate the prevalence of methicillin-resistant staphylococci (mrs) which is a potencial risk factor of transmission between animals and humans in different types of horses (harness racing-horses, breeding mares and riding-horses) and to compare the antimicrobial resistance of the isolates. | 2013 | 23620832 |
| necrotizing fasciitis caused by methicillin-resistant staphylococcus pseudintermedius at a previously irradiated site in a dog. | a great dane dog was presented with a small, superficial wound on the left tarsus that rapidly progressed to a large necrotic area. the dog had undergone radiation therapy in the left tarsal region 33 months previously. necrotizing fasciitis was diagnosed on histopathological examination, and bacterial culture revealed methicillin-resistant staphylococcus pseudintermedius. | 2012 | 23633717 |
| mutant prevention concentration of orbifloxacin: comparison between escherichia coli, pseudomonas aeruginosa, and staphylococcus pseudintermedius of canine origin. | the mutant prevention concentration (mpc) is an important parameter to evaluate the likelihood of growth of fluoroquinolone-resistant mutants for antimicrobial-pathogen combinations. the mpcs of fluoroquinolones for different canine pathogens have not been compared. in this study, we compared for the first time orbifloxacin mpcs between susceptible strains of escherichia coli, pseudomonas aeruginosa, and staphylococcus pseudintermedius of canine origin. | 2013 | 23634902 |
| characterization of the biofilm forming ability of staphylococcus pseudintermedius from dogs. | staphylococcus pseudintermedius is an opportunistic pathogen of dogs and has emerged as a leading cause of skin, wound and surgical site infections worldwide. methicillin resistance is common and clinical infections as a result of methicillin-resistant s. pseudintermedius (mrsp) pose a clinical challenge. in other staphylococci, biofilm formation has been shown to be a virulence factor for infection, however, it has received little attention in s. pseudintermedius. the objectives of this study w ... | 2013 | 23641755 |
| staphylococcus pseudintermedius heterogeneously expresses the meca gene. | 2013 | 23642412 | |
| prevalence of staphylococcal enterotoxins in staphylococcus pseudintermedius isolates from dogs with pyoderma and healthy dogs. | to investigate the role of staphylococcal enterotoxins (ses) produced by staphylococcus pseudintermedius in the pathogenesis of pyoderma, isolates from dogs with pyoderma and healthy dogs were analyzed. according to reverse passive latex agglutination, 14/184 isolates (7.6%) from dogs with pyoderma and 9/87 (10.3%) from healthy dogs produced ses (sea, sec or sed). according to multiplex pcr, 99 isolates (53.7%) from dogs with pyoderma and 97 (90.8%) from healthy dogs possessed one or more se gen ... | 2013 | 23659343 |
| methicillin-resistant staphylococcal contamination of clothing worn by personnel in a veterinary teaching hospital. | to determine the methicillin-resistant staphylococcus aureus (mrsa) and methicillin-resistant staphylococcus pseudintermedius (mrsp) contamination rate of white coats (wc) and surgical scrubs (ss) worn by personnel at the ontario veterinary college health sciences centre (ovchsc) and to identify risk factors associated with clothing contamination. | 2013 | 23662728 |
| antimicrobial resistance, virulence genes, and genetic lineages of staphylococcus pseudintermedius in healthy dogs in tunisia. | nasal swabs of 100 healthy dogs were obtained in 2011 in tunisia and tested for staphylococcus pseudintermedius recovery. antimicrobial resistance profile and virulence gene content were determined. multilocus-sequence-typing (mlst) and smai-pulsed-field gel electrophoresis (pfge) were investigated. s. pseudintermedius was recovered in 55 of the 100 tested samples (55 %), and one isolate per sample was further studied. all 55 s. pseudintermedius isolates were susceptible to methicillin (mssp) bu ... | 2013 | 23686400 |
| the joint in vitro action of polymyxin b and miconazole against pathogens associated with canine otitis externa from three european countries. | canine otitis externa, an inflammation of the external ear canal, can be maintained and worsened by bacterial or fungal infections. for topical treatment, combinations of anti-inflammatory and antimicrobial ingredients are mainly used. | 2013 | 23721182 |
| multi-drug and methicillin resistance of staphylococci from canine patients at a veterinary teaching hospital (2006-2011). | over the past 10 years, an increase in methicillin and multi-drug resistant staphylococcal species has been identified worldwide and anecdotally reported within our veterinary teaching hospital. | 2013 | 23721478 |
| methicillin-resistant staphylococcus pseudintermedius as causative agent of dairy cow mastitis. | 2013 | 23723102 | |
| in vitro efficacy of the essential oil from leptospermum scoparium (manuka) on antimicrobial susceptibility and biofilm formation in staphylococcus pseudintermedius isolates from dogs. | staphylococcus pseudintermedius is a common pathogen of skin and ear infections in dogs. the widespread and rapid emergence of meticillin-resistant s. pseudintermedius (mrsp) has created therapeutic challenges in veterinary medicine and the need for alternative treatments. | 2013 | 23772881 |
| first detection of methicillin-resistant staphylococcus aureus st398 and staphylococcus pseudintermedius st68 from hospitalized equines in spain. | eight coagulase-positive staphylococci from equines with different pathologies obtained between 2005 and 2011 were investigated. isolates were characterized by different molecular techniques (spa-, agr-, mlst), and clonal relatedness of strains was investigated by apai and smai pfge. anti-microbial resistance and virulence profiles were determined. six isolates were identified as staphylococcus aureus, and two as staphylococcus pseudintermedius. of these, four isolates were methicillin-resistant ... | 2014 | 23773775 |
| detection of mecc-positive staphylococcus aureus (cc130-mrsa-xi) in diseased european hedgehogs (erinaceus europaeus) in sweden. | recently, a novel mec gene conferring beta-lactam resistance in staphylococcus aureus has been discovered. this gene, mecc, is situated on a sccmec xi element that has to date been identified in clonal complexes 49, 130, 425, 599 and 1943. some of the currently known isolates have been identified from animals. this, and observations of meca alleles that do not confer beta-lactam resistance, indicate that mec genes might have a reservoir in staphylococcus species from animals. thus it is importan ... | 2013 | 23776626 |
| genome sequence of methicillin-resistant staphylococcus pseudintermedius sequence type 233 (st233) strain k7, of human origin. | we report the genome sequence of the methicillin-resistant staphylococcus pseudintermedius strain k7, isolated from the nares of a veterinarian in seoul, south korea. | 2013 | 23788539 |
| in vitro comparison of the effectiveness of polihexanide and chlorhexidine against canine isolates of staphylococcus pseudintermedius, pseudomonas aeruginosa and malassezia pachydermatis. | polihexanide (polyhexamethylene biguanide) is an antiseptic substance that plays a prominent role in the treatment of critically colonized or infected acute and chronic wounds in humans. | 2013 | 23789723 |
| molecular characterization of the multiple interactions of spsd, a surface protein from staphylococcus pseudintermedius, with host extracellular matrix proteins. | staphylococcus pseudintermedius, a commensal and pathogen of dogs and occasionally of humans, expresses surface proteins potentially involved in host colonization and pathogenesis. here, we describe the cloning and characterization of spsd, a surface protein of s. pseudintermedius reported as interacting with extracellular matrix proteins and corneocytes. a ligand screen and western immunoblotting revealed that the n-terminal a domain of spsd bound fibrinogen, fibronectin, elastin and cytokerati ... | 2013 | 23805283 |
| genetic relatedness, antimicrobial and biocide susceptibility comparative analysis of methicillin-resistant and -susceptible staphylococcus pseudintermedius from portugal. | forty methicillin-resistant and -susceptible staphylococcus pseudintermedius (mrsp and mssp, respectively) from colonization and infection in dogs and cats were characterized for clonality, antimicrobial, and biocide susceptibility. mssp were genetically more diverse than mrsp by multi-locus sequence typing and pulsed-field gel electrophoresis. three different spa types (t06, t02, t05) and two sccmec types (ii-iii and v) were detected in the mrsp isolates. all mrsp and two mssp strains were mult ... | 2014 | 23819785 |
| in vitro adherence of staphylococcus pseudintermedius to canine corneocytes is influenced by colonization status of corneocyte donors. | the current knowledge of in vitro adherence of staphylococcus pseudintermedius to canine corneocytes is limited to comparative analyses between strains, staphylococcal species or corneocytes collected from different breeds, body sites and hosts. however, the role played by colonization status of corneocyte donors remains unknown. the aim of this study was to evaluate the adherence properties of commensal s. pseudintermedius strains to corneocytes collected from dogs with different colonization s ... | 2013 | 23834238 |
| inactivation of microorganisms by low-frequency high-power ultrasound: 1. effect of growth phase and capsule properties of the bacteria. | the aim of this study was to determine the effects of high-intensity low-frequency (20 khz) ultrasound treatment on the viability of bacteria suspension. more specifically, we have investigated the relationship between the deactivation efficiency and the physical (size, hydrophobicity) and biological (gram-status, growth phase) properties of the microbes. enterobacter aerogenes, bacillus subtilis, staphylococcus epidermidis, s. epidermidis sk and staphylococcus pseudintermedius were chosen for t ... | 2014 | 23835398 |
| clonal dynamics of nasal staphylococcus aureus and staphylococcus pseudintermedius in dog-owning household members. detection of mssa st(398). | the objective of this study was to investigate the dynamics of nasal carriage by staphylococcus aureus (sa) and staphylococcus pseudintermedius (sp) among healthy dog-owning household members involved in 7 previous index cases of suspected anthropozoonotic (n = 4) and zoonotic (n = 3) interspecies transmission [4 direct cases, identical sa (n = 3) or sp (n = 1) in owner and dog; three indirect, sp in owner (n = 2) or sa in dog (n = 1)]. co-carriage with methicillin-resistant coagulase-negative s ... | 2013 | 23874949 |
| antibiotic treatment of resistant infections in small animals. | there are few veterinary clinical studies to support a recommended use and dose for treating resistant bacterial infections in small animals. resistance against many common antibiotics is possible and a susceptibility test is advised. infections caused by pseudomonas aeruginosa presents a special problem. staphylococcus isolated from small animals is most likely to be staphylococcus pseudintermedius. the most important resistance mechanism for staphylococcus is methicillin resistance. the only a ... | 2013 | 23890241 |
| animal and human staphylococcus aureus associated clonal lineages and high rate of staphylococcus pseudintermedius novel lineages in spanish kennel dogs: predominance of s. aureus st398. | methicillin-susceptible staphylococcus aureus (mssa) and staphylococcus pseudintermedius (mssp) are gaining interest to track the evolution of emerging methicillin-resistant strains in animals and humans. we focused on the characterization of the methicillin-susceptible coagulase-positive staphylococci (mscops) recovered from nasal samples of 98 healthy kennel-dogs. isolates were typed by spa, agr, mlst and smai/apai-pfge. antimicrobial resistance and virulence profiles were investigated. presen ... | 2013 | 23932077 |
| in vitro evaluation of dispersinb on methicillin-resistant staphylococcus pseudintermedius biofilm. | methicillin resistant staphylococcus pseudintermedius (mrsp) is an important canine pathogen that has been shown to produce biofilm in vitro. biofilm production may be an important virulence factor and methods to eliminate biofilm-associated infections are required. an enzyme of aggregatibacter actinomycetemcomitans, dispersinb, has been shown to degrade the extracellular matrix in the biofilm of a variety of bacteria including staphylococcus aureus and staphylococcus epidermidis. the objective ... | 2013 | 23932310 |
| pharmacodynamics of doxycycline and tetracycline against staphylococcus pseudintermedius: proposal of canine-specific breakpoints for doxycycline. | doxycycline is a tetracycline that has been licensed for veterinary use in some countries, but no clinical breakpoints are available for veterinary pathogens. the objectives of this study were (i) to establish breakpoints for doxycycline and (ii) to evaluate the use of tetracycline as a surrogate to predict the doxycycline susceptibility of staphylococcus pseudintermedius isolates. mics and inhibition zone diameters were determined for 168 canine s. pseudintermedius isolates according to clinica ... | 2013 | 23966509 |
| novel pseudo-staphylococcal cassette chromosome mec element (ψsccmec57395) in methicillin-resistant staphylococcus pseudintermedius cc45. | genetic characterization of methicillin-resistant staphylococcus pseudintermedius (mrsp) from thailand and israel revealed the presence of a predominant atypical clonal lineage which was not typeable by smai-pfge and sccmec typing. all the atypical isolates (n = 34) belonged to cc45 (30 st45 and 2 st179 isolates, 1 st57 isolate, and 1 st85 isolate). the isolates originated from healthy and diseased dogs and cats, as well as from the environment of one clinic. cfr9i-pulsed-field gel electrophores ... | 2013 | 23979735 |
| a novel fexa variant from a canine staphylococcus pseudintermedius isolate that does not confer florfenicol resistance. | transposon tn558 integrated in the chromosomal radc gene was detected for the first time in staphylococus pseudintermedius. it carried a novel fexa variant (fexav) that confers only chloramphenicol resistance. the exporter fexav exhibited two amino acid substitutions, gly33ala and ala37val, both of which seem to be important for substrate recognition. site-directed mutagenesis that reverted the mutated base pairs to those present in the original fexa gene restored the chloramphenicol-plus-florfe ... | 2013 | 23979755 |
| first report in south america of companion animal colonization by the usa1100 clone of community-acquired meticillin-resistant staphylococcus aureus (st30) and by the european clone of methicillin-resistant staphylococcus pseudintermedius (st71). | methicillin-resistant staphylococci can colonize and cause diseases in companion animals. unfortunately, few molecular studies have been carried out in brazil and other countries with the aim of characterizing these isolates. consequently, little is known about the potential role of companion animals in transmitting these resistant bacteria to humans. in this work we searched for meca gene among staphylococcus isolates obtained from nasal microbiota of 130 healthy dogs and cats attended in a vet ... | 2013 | 23981343 |
| evaluation of the affinity of various species and strains of staphylococcus to adhere to equine corneocytes. | meticillin-resistant staphylococcus aureus (mrsa) strain usa 500 predominately colonizes horses and people working with them. previous studies demonstrate that some staphylococcus species exhibit higher affinity for corneocytes of specific mammalian species. | 2013 | 23992283 |
| incidence of inducible clindamycin resistance in staphylococcus pseudintermedius from dogs. | clindamycin is increasingly used to treat canine pyoderma. eight of 608 staphylococcus pseudintermedius isolates were positive for inducible clindamycin resistance by double-disk diffusion testing and pcr detection of ermb. staphylococcus pseudintermedius isolates that are erythromycin resistant but clindamycin susceptible by in vitro antimicrobial susceptibility testing should be tested for inducible clindamycin resistance. | 2013 | 24025915 |
| an in vitro study to determine the minimal bactericidal concentration of sodium hypochlorite (bleach) required to inhibit meticillin-resistant staphylococcus pseudintermedius strains isolated from canine skin. | meticillin-resistant staphylococcus pseudintermedius (mrsp) is becoming a more common pathogen in animals treated in veterinary hospitals, raising concerns for transmission and possible contamination of the hospital itself. the identification of effective agents for the decontamination of veterinary patients and hospitals is crucial. sodium hypochlorite (6.15%) or 'bleach' is an inexpensive and frequently used decontamination agent in human and veterinary hospitals and an adjunctive treatment fo ... | 2013 | 24118401 |
| an investigation of resistance to β-lactam antimicrobials among staphylococci isolated from pigs with exudative epidermitis. | a high proportion of staphylococci isolated from pigs affected with exudative epidermitis were found to be resistant to β-lactam antimicrobials. the primary objective of this research was to investigate and characterize β-lactam resistance in staphylococcus hyicus, staphylococcus aureus and other staphylococci isolated from these pigs. | 2013 | 24131819 |
| characterisation of a catalase-negative methicillin-resistant staphylococcus aureus isolate from a dog. | a catalase-negative mrsa strain and a methicillin resistant staphylococcus pseudintermedius strain (mrsp) were isolated from a dog affected by a severe form of pododermatitis. the catalase negative isolate was typed as sccmec i, pvl negative, st5 t002 strain. a deletion at position 487 of the kat gene altered the functionality of the catalase enzyme. this is the first report of a catalase-negative mrsa in animals. as catalase test is a rapid assay routinely employed for the identification of sta ... | 2013 | 24139722 |
| adverse effects of rifampicin in dogs and serum alanine aminotransferase monitoring recommendations based on a retrospective study of 344 dogs. | rifampicin has been reported to have potent activity against staphylococci, including meticillin-resistant staphylococcus pseudintermedius. there is limited documented information regarding adverse effects and recommendations for serum biochemistry monitoring. | 2013 | 24164464 |
| canine antimicrobial peptides are effective against resistant bacteria and yeasts. | antimicrobial peptides (amps) are small proteins present in most living species and they are involved in the defence against pathogenic organisms. β-defensins and cathelicidin are the most frequently studied amps in both people and dogs. | 2014 | 24215268 |
| use of linezolid to treat mrsp bacteremia and discospondylitis in a dog. | a 1.5 yr old male german shepherd dog was evaluated for recurrent intermittent episodes of fever and lethargy. clinicopathologic abnormalities were suggestive of a discospondylitis at the seventh and eighth thoracic vertebrae. blood and urine cultures yielded growth of methicillin-resistant staphylococcus pseudintermedius (mrsp) that was resistant to all commonly used antibiotics. extralabel antibiotic susceptibility testing demonstrated susceptibility of both blood and urine isolates to linezol ... | 2015 | 24216492 |
| dam-to-offspring transmission and persistence of staphylococcus pseudintermedius clones within dog families. | staphylococcus pseudintermedius is an opportunistic pathogen that causes mainly skin infections in dogs. although vertical transmission of s. pseudintermedius strains from dam to offspring has been reported, the persistence of the dam's strains in offspring over long periods of time is virtually unknown. | 2014 | 24267321 |
| case-control risk factor study of methicillin-resistant staphylococcus pseudintermedius (mrsp) infection in dogs and cats in germany. | methicillin-resistant staphylococcus pseudintermedius (mrsp) has emerged as a highly drug-resistant small animal veterinary pathogen. although often isolated from outpatients in veterinary clinics, there is concern that mrsp follows a veterinary-hospital-associated epidemiology. this study's objective was to identify risk factors for mrsp infections in dogs and cats in germany. clinical isolates of mrsp cases (n=150) and methicillin-susceptible s. pseudintermedius (mssp) controls (n=133) and the ... | 2014 | 24290489 |
| prevalence of methicillin-resistant staphylococcus spp. in the conjunctival sac of healthy dogs. | to determine the prevalence of selected coagulase-positive methicillin-resistant staphylococcus aureus (mrs) in the conjunctival sac in a group of healthy dogs and to compare the prevalence of ocular mrs colonization with colonization of typically assessed body sites including the nasal cavity and rectum. | 2015 | 24299189 |
| canine superficial bacterial folliculitis: current understanding of its etiology, diagnosis and treatment. | superficial bacterial folliculitis (sbf) is more common in the dog than other mammalian species. until recently, a successful outcome in cases of canine sbf was possible by administering a potentiated amoxicillin, a first generation cephalosporin or a potentiated sulfonamide. unfortunately, this predictable susceptibility has changed, because methicillin resistant staphylococcus pseudintermedius (mrsp) and staphylococcus aureus (mrsa) are becoming more prevalent in canine sbf cases. the increasi ... | 2014 | 24345778 |
| design and application of a loop-mediated isothermal amplification assay for the rapid detection of staphylococcus pseudintermedius. | staphylococcus pseudintermedius is a commensal and opportunistic pathogen of dogs. it is mainly implicated in canine pyoderma, as well as other suppurative conditions of dogs. although bacterial culture is routinely used for clinical diagnosis, molecular methods are required to accurately identify and differentiate s. pseudintermedius from other members of the staphylococcus intermedius group. these methods, owing largely to their cost, are not easy to implement in nonspecialized laboratories or ... | 2014 | 24398904 |