Publications

TitleAbstractYear
Filter
PMID(sorted ascending)
Filter
procoagulant activity of activated monocytes.endotoxin-stimulated monocytes develop a very high tissue-factor-like activity as compared to an equivalent number of monocytes in a preparation of monocyte-enriched mononuclear blood cells obtained by ficoll-urovision density gradient centrifugation which is not exposed to endotoxin. in monocytes which were obtained by plastic adherence from the monocyte-enriched mononuclear blood cells, the tissue factor activity was as high as in the endotoxin-stimulated monocytes.1977346452
influence of bacteriological media constituents on the reproduction of salmonella enteritidis bacteriophages.three different salmonella enteritidis phages were isolated and purified from raw sewage by agar-layer technique. the sensitivity of the host organisms toward phages was changed when they were grown on different bacteriological media. the effect of single components of the medium on phage reproduction was determined by the omission of that substance from the medium. cacl2,mgso4, and glycerol each had a pronounced stimulatory effect on the phage reproduction, while bile salts had a profound inhib ...1978350148
immunochemistry of salmonella o-antigens: preparation of an octasaccharide-bovine serum albumin immunogen representative of salmonella serogroup b o-antigen and characterization of the antibody response.the o-antigenic polysaccharide of phenol-water extracted salmonella typhimurium (o antigens 4, 12) lipopolysaccharide was enzymatically cleaved by phage p22 endorhamnosidase. an octasaccharide with the (formula: see text) structure gal-man-rha-gal-man-rha was isolated and shown to retain the o-antigen 4 specificity of the native polysaccharide. after oxidation of the terminal reducing rhamnose residue to the corresponding aldonic acid, the octasaccharide was covalently linked to bovine serum alb ...1978351058
diarrhoeal disorders of bacterial origin in jakarta.during a 21-month period from april 1974 to february 1976, 948 children with gastroenteritis were studied. aetiologic agents were identified in 43% of these patients. isolates were identified as follows: v. cholera el tor, 273 (67%); salmonella enteritidis, 64 (16%); enteropathogenic e. coli, 28 (7%); shigella, 28 (7%); vibrio (nag), 9 (2%): and v. parahaemolyticus, 7,2%). gastroenteritis with dehydration is a serious continuing pediatric problem in jakarta, constituting 30% of admissions to sum ...1977351819
[transfer of substituted sex factor f'lac in salmonellae]. 1978352052
[identification of lac+ -salmonellae]. 1978352068
studies in vitro on the reaction of peritoneal exudate cells from mice immune to infection with nematospiroides dubius with the infective third stage larvae of this parasite.the results of the present study show that peritoneal exudate cells from mice immune to infection with nematospiroides dubius are able in vitro to damage the third stage infective larvae as measured by a loss in infectivity. the ability of these cells to function in the absence of specific antibody seems to be related to the presence of trypsin labile factors on their surfaces. lymphocytes from immune mice are also able to damage the larvae. the suggestion is made that 'activated' macrophages ma ...1978352325
microfloral comparison of fresh and thawed frozen fryers. 1978353775
animal salmonellosis in peninsular malaysia. ii. annual and zoological distribution of salmonella serotypes over the 10-year period 1966-1975.a total of 860 salmonella isolations were made in peninsular malaysia from 15 animal species (domestic and wild), eggs, molluscs, flies, and animal feed. the isolations were distributed among 31 serotypes in eight groups. the most common serotype isolated was salmonella pullorum, followed by s. choleraesuis and s. infantis. s. typhimurium had the widest zoological distribution. the importance of controlling animal salmonellosis is emphasized.1978354419
transconjugant analysis: limitations on the use of sequence-specific endonucleases for plasmid identification.we used the sequence-specific endonucleases ecori, smai, bamhi, hsui, and haeiii as identification tools in following the conjugal transfer of the well-studied r plasmids sa, r388, rp4, and r6k. transfers were both intergeneric and intrageneric. plasmid fingerprints were generated from both single- and combination-enzyme digests. the sa transconjugants yielded plasmids showing consistent fingerprints for each of the respective endonucleases used, whereas the three other r-plasmid transconjugants ...1978357414
biological and physicochemical characteristics of four serotypes of salmonella enteritidis.four serotypes of salmonella enteritidis, anatum atcc 9270, newbrunswick atcc 1608, oranienburg 200 e, and pullorum rm, were studied to determine biological, chemical, or physical differences which might explain variations in salmonella virulence as previously reported by mccullough and eisele (j. infect. dis. 88:278-289, 1951; 89:259-265, 1951). these investigators found that serotype pullorum was significantly less virulent than serotypes newport, derby, barielly, meleagridis and anatum when f ...1978361563
growth of salmonellae in orally infected germfree mice.germfree mice were infected intragastrically, intravenously, or intraperitoneally with 10(3) to 10(9) viable salmonella typhi ty2, s. gallinarum 9240, or s. enteritidis 5694. the 50% lethal doses were compared with those for conventionally raised mice. substantial growth of the salmonellae occurred in the intestinal tract of the germfree mice but, despite the presence of more than 10(9) viable s. typhi or s. gallinarum in the lumen, the liver and spleen cultures remained salmonella-free, and all ...1978361568
endotoxin-induced interruption of early pregnancy in the rabbit.endotoxin derived from salmonella enteritidis (boivin) completely interrupted pregnancy in the rabbit when given as a single dose (10 or 20 microgram/kg) intravenously on day 4 or day 8 of pregnancy. indomethacin (2 or 10 mg/kg) was unable to prevent this effect.1978361951
[institutional epidemic gastroenteritis caused by salmonella enteritis worthington type in 1976].an outbreak of gastroenteritis that occurred in a boarding school in mexico is described. the attack rate was 100% since all of 151 pupils were involved. salmonella enteritidis serotype worthington was identified as the only etiologic agent. this microorganism was isolated from 60% of the samples studied. due to the delay in notification the food ingested during the outbreak could not be analyzed.1979363132
[biochemical properties of salmonella enteritidis used for rodent control]. 1978364255
protective effects of a supernatant factor from salmonella typhimurium on salmonella typhimurium infection of inbred mice.a supernatant factor prepared from 48-h cultures of salmonella typhimurium has been used to immunize mice against subsequent challenge with normally lethal doses of s. typhimurium. the mouse strains used, c57bl and balb/c, were sensitive to s. typhimurium with 50% lethal doses of less than 50 organisms. two doses of supernatant factor, given intraperitoneally 20 days apart, protected mice against a subcutaneous challenge dose 10 days later of 100 50% lethal doses of s. typhimurium, resulting in ...1978365739
intestinal colonization and virulence of salmonella in mice.within 3 h after oral challenge of mice with salmonella typhimurium, foci of infection developed in the peyer's patches of the small intestine. the numbers of organisms in the cecum, although in excess of those found in the small intestine, were not firmly associated with the cecal wall but were present largely in the cecum's contents. the peyer's patches at first were remarkably incapable of eliminating even small numbers of salmonella, but at about 7 days after infection developed the ability ...1978365768
incidence of infections with salmonella enteritidis serotypes in black and indian children. a 16-year survey.a 16-year survey (1960--1975) of salmonella infections other than typhoid fever in black and indian children admitted to king edward viii hospital, durban, is reported. the 3,393 patients yielded 3,688 salmonella enteritidis serotypes, mainly typhimurium, johannesburg/duval, manhattan, enteritidis, and senftenberg. organisms were isolated from one or more of the following: stool, urine, blood, cerebrospinal fluid, liver, sputum, subcutaneous tissue, ear and bone. patients' ages varied from 1 day ...1978366775
bone and joint infections due to salmonella.a search of the records at the new york city department of health and the charts of patients at columbia presbyterian hospital identified 37 cases of bone infection and nine cases of joint infection due to salmonella between 1964 and 1978. factors that apparently contributed to the development of either osteomyelitis or septic arthritis in 23 of the patients included hemoglobinopathy, previous trauma or surgery, connective tissue disorder, and lymphoma. salmonella typhimurium and salmonella ente ...1978368264
the child who is a salmonella carrier. to treat or not to treat? 1979371891
contraceptive properties of endotoxin in rabbits.endotoxin derived from salmonella enteritidis-boivin at a dose of 20 micrograms/kg intravenously interfered with follicular rupture normally induced by human chorionic gonadotropin (hcg) in rabbits. this action was greatest when the endotoxin was given 5 to 6 hours after the administration of hcg. the failure of follicular rupture resulted in entrapment of ova. endotoxin (5 micrograms/kg) given intravenously to rabbits on day 4 of pregnancy resulted in failure of implantation. indomethacin (2 mi ...1979371991
abdominal aortic salmonellosis.a recent example of salmonella mycotic abdominal aortic aneurysm is presented together with a review of the 24 other cases in the literature. emphasis is placed on common modes of presentation, diagnosis, and surgical management. a review of current theories of etiology is presented along with a new, more descriptive classification of mycotic aneurysms.1979373152
mucosal defenses against salmonella infection in the mouse.specific pathogen-free icr (institute of cancer research) mice were challenged with salmonella orally, aerogenically, or parentally 24 hr after they received sublethal whole-body irradiation. the early growth for the sublethal inoculum was identical in irradiated and control mice. in the irradiated group, salmonella multiplied in the liver and spleen until death of the host. increasing the dose of irradiation reduced the size of the mean lethal dose for the intravenous, intraperitoneal, and aero ...1979374651
protective effect of oral salmonella enteritidis 11rx infection against colon tumor induction by 1,2-dimethylhydrazine in mice.infection of mice with salmonella enteritidis 11rx has been shown previously to cause nonspecific immune stimulation and, consequently, resistance to subsequent challenge with a variety of transplantable tumors. the present study has examined the effect of infection with this organism in a chemical carcinogenesis system. colonic tumors were induced in laca and balb/c x c57bl/6jf1 mice by weekly s.c. injection of 1,2-dimethylhydrazine (15 mg/kg) for 28 weeks. infection of mice p.o. with live s. e ...1979376122
the incidence of salmonella in random-source cats purchased for use in research.in research facilities, cats are routinely ignored as a potential source of salmonella infection. over a period of 18 months, 142 cats received from commercial vendors for use in research were screened for enteric salmonella. salmonella was isolated from 15 animals, an incidence of 10.6%. five (29%) of the 17 shipments contained animals that were positive for salmonella. the serotypes isolated were salmonella derby, salmonella typhimurium, salmonella anatum, salmonella enteritidis, and salmonell ...1979376759
[purification and physico-chemical analysis of the fimbrial antigen in two different genera of enterobacteriacea: salmonella enteritidis and yersinia enterocolitica (author's transl)].chemical, physical and immunological properties of the fimbrial antigen of two different genera of enterobacteriaceae, namely salmonella (s. enteritidis) and yersinia (y. enterocolitica) were analysed. only a few strains of these two bacterial genera possess a fimbrial antigen which proved to be identical in all tests. purified fimbriae are unstable in buffer solutions. they tend to form aggregates, patterns of which are between 240000 and 270000. submitted to solubility testing by various metho ...1979377854
late deoxyribonuclease activity of salmonell enteritidis.as a result of chance observations, the authors studied for deoxyribonuclease activity 16 strains of salmonella, including six fresh isolates and ten stock cultures, with positive results in 13. reactions characteristically occurred at 48 hours or later, with the majority being manifest at 72 hours and the latest at six days. no other positive reaction was observed among approximately 7,000 enterobacteriaceae tested, except for serratia species and proteus vulgaris. deoxyribonuclease screening p ...1979377948
increased insulin responsiveness in endotoxicosis.the relation of endotoxicosis to insulin responsiveness was evaluated in male holtzman rats. salmonella enteritidis lipopolysaccharide at 0.5 or 1.0 mg per 300 g rat increased lethality in convulsive seizure deaths to 0.25, 0.50, or 1.0 u insulin sc. the hypoglycemic nadir induced by 0.05, 0.10, or 0.25 u of insulin sc was greater in rats rendered endotoxic with 1 mg of lipopolysaccharide iv. oxidation of u-14c-d-glucose to 14 co2 by endotoxic tissues in vitro was augmented in liver slices, epid ...1979378453
[epidemiological study of an outbreak of gastroenteritis caused by salmonella enteritidis ser hildelberg in mexico, 1975]. 1978380013
genetics of natural resistance to salmonellae in mice.the genetics of natural resistance to salmonellae were studied in f1 hybrid and backcross mice. overall resistance to salmonella typhimurium c5 is complex, but one parameter, the early net growth rate of the organism in vivo, is controlled by a single autosomal gene or cluster of genes. 'slow' net growth rate is necessary but insufficient, for resistance to s. typhimurium c5. resistance requires the participation of other mechanisms, detectable by the end of the first week, which presumably invo ...1979381179
the removal of 14c labeled endotoxin by activated charcoal.endotoxin shock due to gram-negative enteric bacteria is of major medical concern with an estimated 100,000 fatalities in the united states per year. an effective therapy for endotoxin shock, particularly in combination with significant liver damage, has not been available to date. since activated charcoal is known as a universal sorbent, the use of activated charcoal in a hemoperfusion apparatus to remove endotoxin has interesting possibilities. current assays for endotoxin are inadequate. the ...1979381215
transmissible antibiotic resistance in salmonella isolated from random-source cats purchased for use in research.salmonella isolates from random-source cats designated for use in research were examined for antibiotic susceptibilities and the presence of plasmids containing r factors. the serotypes studied were salmonella derby, s typhimurium, s anatum, s enteritidis, and s bredeney. eighty percent of the isolates were resistant to one or more antibiotics. the greatest frequency of resistance was to streptomycin. the majority of the salmonella isolates transferred all or a part of their antibiotic resistanc ...1979382928
fever and survival in the rat. the effect of enhancing fever.to study the effect of fever on infectious disease in a mammal, rats, partially restrained by an antirotatory device and with chronically implanted preoptic thermodes, were injected with salmonella enteritidis and, in some of them, the hypothalamus was then continuously cooled to enhance the febrile response. all animals developed a fever that peaked 2 days after the infection, reaching 40.9 +/- 0.2 (sd) degrees c in the nine hypothalamic cooled and only 39.8 +/- 0.4 degrees c in the 13 control ...1979384358
[comparison of the methods of detection of different types of salmonella in dairy products]. 1979384497
evaluation of several methods of detecting salmonellae in groups of chickens.chickens exposed experimentally to salmonella agona, s. blockley, s. enteritidis, s. infantis, and s. typhimurium were tested serologically by microagglutination and microantiglobulin procedures and culturally by cloacal swabs and environmental samples. chicks infected at one day old yielded the highest level of positive cloacal swab cultures, whereas exposure of older birds gave maximal serologic titers. recovery of salmonella from environmental samples is dependent on a number of factors, incl ...1979384988
reiter's syndrome after salmonella infection: occurrence in hla--b27 positive brothers. 1979385003
[urinary infection caused by salmonella enteritidis in schistosoma haematobium bilharziasis]. 1979386258
[effectiveness of oral immunization of white mice with a complex s. typhimurium antigen].the protective properties of hydroxylamine preparation obtained from a virulent strain of s. typhimurium were studied in experiments with natural infection after a single oral immunization. the new data obtained in these experiments suggest that the treatment of bacteria with hydroxylamine allows to produce the preparation which, when administered orally, has the immunizing dose only 20 times as great as its immunizing dose for subcutaneous administration. the action of gastric juice on hydroxyl ...1979386669
[salmonelloses in africa. bacteriological and epidemiological findings]. 1979387361
[meningitis caused by salmonellas]. 1979387362
endophthalmitis due to salmonella enteritidis. 1979387934
effect of capsular polysaccharide of klebsiella pneumoniae on host resistance to bacterial infections. iii. further study of its effects on interactions between peritoneal leukocytes and virulent salmonella enteritidis.the mechanism for the infection-promoting effect of the capsular polysaccharide of klebsiella pneumoniae (cps-k) was investigated using the experimental system in which mice were infected intraperitoneally (i.p.) with a virulent strain of salmonella enteritidis immediately after i.p. injection of cps-k. in the peritoneal phagocytes of cps-k-untreated control mice, approximately 70, 3, and 10% of phagocytized bacteria survived 6, 12, and 24 hr after challenge, respectively, when calculated from t ...1979388155
interferon and cytotoxic factor (cytotoxin) released in the blood of mice infected with mycobacterium bovis bcg. ii. influence of time after bcg inoculation on production of interferon and cytotoxin by capsular polysaccharide of klebsiella pneumoniae or by bacterial lipopolysaccharide and on hyperreactivity to their lethal effects.the time course of the occurrence of hyperreactivity in interferon and cytotoxin responses to the active substance (neutral fraction) of the capsular polysaccharide of klebsiella pneumoniae (neutral cps-k) and bacterial lipopolysaccharide (lps) and of the hyperreactivity to their lethal effects was followed after infection with bcg in sma and icr strains of mice. the duration of these hyperreactivities of bcg-infected mice depended on the inoculum doses of bcg. the time patterns of the hyperreac ...1979388156
[clinico-epidemiological analysis of an outbreak of salmonella bredeney infection in newborn infants]. 1979388542
endocarditis caused by salmonella enteritidis.a case of endocarditis caused by salmonella enteritidis is reported in a 20-year-old african woman. this is only the fourth published case. the development of this rare infection in the patient reported here probably resulted from a reduction in immunity caused by pregnancy and a past splenectomy.1979389258
isolation of pathogens other than yersinia pestis during plague investigations.from 1975 to 1978, 37 isolates of pasteurella multocida, 1 of salmonella enteriditis, and 5 of francisella tularensis were recovered from 42 mammalian specimens and 1 flea pool submitted for examination for evidence of infection with yersinia pestis. most of the specimens were collected during investigations of either a human plague infection or a reported epizootic among rodent populations. all specimens were of species regularly or occasionally involved in plague or tularemia cycles in nature ...1979392123
a biological study on hot-water extract from delipidated mycobacterium bovis strain bcg.the biological activity of a hot-water extract from delipidated bcg, designated as hsa (hot-water soluble adjuvant), was investigated. the hsa did not induce hyperreactivity to bacterial endotoxin. the hot-water extract from which nucleic acids had been removed by streptomycin (sm-hsa) was found to enhance the delayed-type hypersensitivity as evidenced by the results of footpad reaction of mice. the hsa and sm-hsa could be injected to mice by an intraperitoneal route for 20 consecutive days with ...1979392813
[interaction between salmonella and schistosomes. scanning electron microscopy study].in our attempts to elucidate the pathogenesis of prolonged salmonella bacteremia in patients with schistosoma mansoni or schistosoma haematobium infection, we have utilised meb. our results are significant. they show an association exists between bilharziasis and salmonellosis.1979393422
subtraction serum bactericidal assay: a method for estimating in vivo effects of antibiotic combinations.the subtraction serum bactericidal assay has been developed to assess the effects of the individual components of antibiotic combinations in serum specimens from patients with serious bacterial infection. the technique can be performed easily with conventional microtiter technology, and the results compare favorably with those obtained by conventional in vitro determinations of the additive and synergistic activity of fixed antibiotic combinations against various enterobacteriaceae. three combin ...1979393780
[enterotoxigenicity of salmonellae]. 1978394392
resistance of essential fatty acid-deficient rats to endotoxic shock.the role of lipids in the altered energy metabolism of shock remains to be delineated fully. during the course of our studies of endotoxic shock, the susceptibility of essential fatty acid (efa)-deficient rats to endotoxin was evaluated. intravenous administration of s. salmonella enteritidis endotoxin (1 mg/100 gm) in normal male long-evans rats (7--8 weeks old) produced severe shock with an 88% mortality. in marked contrast, injection of this dose of endotoxin in efa-deficient rats of the same ...1979394879
diagnosis of salmonella infections: specificity of indirect immunofluorescence for rapid identification of salmonella enteritidis and usefulness of enzyme-linked immunosorbent assay.an indirect immunofluorescence (ifl) method was used for diagnosis of infections caused by salmonella enteritdis during an epidemic. antiserum prepared against the synthetic disaccharide tyvelose 1 leads to alpha 3 d-mannose, representative of salmonella o antigen 9, covalently linked to bovine serum albumin, was used. of 43 decal samples examined, 28 were positive for s. enteritidis by culture. ifl was applied (1) directly on fecal smears, (2) on enrichment broth cultures after incubation for 1 ...1979396337
shigella dysenteriae 1-like cytotoxic enterotoxins produced by salmonella strains.a salmonella enteritidis strain produced a cytotoxin in addition to heat-labile (lt) and heat-stable (st) enterotoxins. two strains of serotypes salmonella kapemba and salmonella thompson were lt and st negative, but exhibited a cytotoxic effect. after sephadex g-100 fractionation of the crude s. enteritidis material, some high and low molecular fractions had both cytotonic and cytotoxic activities. of the two other salmonellae, only some high molecular fractions contained the cytotoxic substanc ...1979396765
cross-protection aginst salmonella enteritidis infection in mice. i. immunization trials.mice were immunized subcutaneously with live and killed vaccines, with and without complete adjuvant incorporating salmonella typhi-murium m206, salmonella gallinarum 9r, salmonella pullorum sp223 as well as homologous salmonella enteritidis se795. the animals were challenged 21 days post-vaccination with 100 ld50 of virulent s. enteritidis 5694 smr subcutaneously along with unvaccinated control mice. to assess the immunity against acute and chronic infections, the percentage of absolute survivo ...1979397731
cross-protection against salmonella enteritidis infection in mice.mice were immunized subcutaneously with live vaccines and live vaccines with complete adjuvant incorporating salmonella enteritidis se 795, salmonella typhi-murium m206, salmonella gallinarum 9r or salmonella pullorum sp223. they were challenged along with unvaccinated controls with 100 ld50 of virulent s. enteritidis 5694 smr subcutaneously on the 21st day post-vaccination. the humoral immune response was studied by assessing the sequential level of agglutinins, complete and incomplete somatic ...1979397732
cross-protection against salmonella enteritidis infection in mice. iii. delayed hypersensitivity reaction and clearance of the challenge organism.mice were immunized with live vaccines and with live vaccines with complete adjuvant incorporating salmonella enteritidis, salmonella typhi-murium, salmonella gallinarum or salmonella pullorum. on the 21st day after vacination, the hypersensitivity reactions elicited by the mice to extracts of the challenge organism (s. enteritidis 5694 smr) were assessed. the degree of delayed hypersensitivity reaction was compared with the level of protection induced by the vaccine. the role in protection of d ...1979397733
a supplemental test system to measure competitive exclusion of salmonellae by native microflora in the chicken gut.an improved individual challenge test system is described for evaluation of competititve exclusion of salmonellae in day-old chicks by native gut microflora. evaluation of salmonella protection is based on culture of cloacal and fecal samples by enrichment methods plus enumeration of salmonellae in fresh droppings collected from test groups. the use of a nalidixic-acid-resistant strain of salmonella allowed for ease of measurement. comparative data are included that were developed by parallel te ...1979397829
inhibition of the growth of lewis lung carcinoma in syngeneic mice by salmonella antigens.administration of a protein antigen preparation from salmonella enteritidis 11rx at the site of challenge with lewis lung carcinoma inhibited tumour development in mice previously immunised with live bacteria, but not control mice. the kinetics of tumour growth indicated that the inhibition of tumour development was due to a reduction of the initial tumour inoculum rather than the development of specific anti-tumour immunity.1979398698
the intestinal flora and infant botulism.the intestinal flora of experimental animals interferes with infection by species of salmonella and shigella. protection against infection with these organisms appears to be related to high concentrations of volatile acids, low ph, and low oxidation-reduction potential of the intestinal contents of animals with an intact flora. there are no data to show that the flora influences colonization of the intestine with clostridial species, but indirect evidence suggests that the intestinal flora may b ...1979399374
[infections by enteritis-salmonellae in newborn and premature infants]. 1979399405
carbohydrate metabolism in c3h/hej (nonresponder) mice during endotoxic shock.this study was undertaken to evaluate the hypoglycemic effects of endotoxin in c3h/hej (nonresponder) mice. endotoxin from salmonella enteritidis ser typhimurium strain sr-11 was used and the median lethal dosed (ld50) for random-outbred swiss-webster mice and c3h/hej mice were 450 microgram and 3,000 microgram, respectively. at intervals after intraperitoneal injection of endotoxin (1 ld50) animals were killed, and blood glucose, liver glucose, and liver glycogen levels were killed, and blood g ...1979400573
enhancement of nonspecific immunity to bacterial infection by cord factor (6,6'-trehalose dimycolate).the capacity of mycobacteria to enhance the nonspecific resistance of mice to bacterial infections was related to the presence of cord factor. after enzymatic digestion and delipidation, cell walls lost their immunopotentiating activity, which was restored, however, by the addition of cord factor. cord factor administered alone protected mice effectively against virulent organisms unrelated to mycobacteria. moreover, although this glycolipid is usually injected as a solution in mineral oil, our ...1977404368
[study of intestinal infections in experiments on monkeys]. 1977410189
[mechanism of the changes in the animal reactivity to tularemia in mixed infection].experiments were conducted on albino rats infected with listeria or salmonelloses, and then with tularemia; differences were revealed in the duration of manifestation of nonspecific resistance associated with peculiarities of pathogenesis and immunogenesis of the background infections. one of the significant factors causing an increase of albino rats resistance to tularemia in mixed infection was activation of the immunomorphological reaction promoting accelerated development of specific immunit ...1978415458
[aggravation of experimental dysentery in mice and acceleration of the process of multiplication of pathogenic and conditionally pathogenic bacteria under the effect of yeast rna].simultaneous infection of mice with sh. flexneri subtype 2a, culture, with various doses of rna sodium salt (narna) or administration of the preparation 3 hours prior to or 6, 12, and 18 hours after the infection was accompanied by aggravation of the experimental infection in mice. this was expressed in a greater number of animals which contracted the disease and died, and in increased blood and peritoneal exudate microbiol density. the same processes were noted in mice infected with equal doses ...1978415460
[salmonella-cholecystitis (author's transl)].gastroenteritis due to salmonella enteritis is an endemic disease in our region, extraintestinal manifestations however are rare. we report a 8 years old girl who presented after 4 days of an unspecific diarrheal disease with watery liquid stools, vomiting, abdominal cramps, fever above 39 grad c and symptoms and signs of an acute abdominal emergency. mid abdominal laparotomy disclosed a cholecystitis with reactive peritonitis. cultures of bile showed salmonella group b as the causative organism ...1979530733
lethality for mice and chick embryos, pyrogenicity in rabbits and ability to gelate lysate from amoebocytes of limulus polyphemus by lipopolysaccharides from bacteroides, fusobacterium and veillonella.phenol-water extracted lipopolysaccharides (lps) from veillonella, fusobacterium nucleatum, bacteroides fragilis and bacteroides melaninogenicus were lethal for mice and 11-days-old chick embryos, pyrogenic in rabbits, and gelated limulus amoebocyte lysate. mouse lethality was considerably enhanced by actinomycin-d. in all test systems the endotoxin activity of veillonella and fusocbacterium lps was comparable to that of lps from salmonella enteritidis, which was included as a reference endotoxi ...1977564596
[structure of the salmonella from animals, birds and the environment through the period of 1970-1975].studied were biochemically and serologically the species of a total of 8738 salmonella cultures. most of the investigated strains belonged to subgenus i--95 species; to subgenus ii belonged one species (salmonella sofia); to subgenus iii belonged 4 species: salmonella arizonae 11:b:1, 7; salmonella arizonae 35:r:z35; salmonella arizonae 35:z52:1, 5, 7; salmonella arizonae 58:rz53:z57 of three serologic groups. the attention was focused on more than 20 (new to this country) salmonellae among whic ...1977595376
[serological examinations on natural infections with mouse pathogens in inbred mouse strains: difference in antibody detection among the strains (author's transl)].serological surveys on several infections were performed on the inbred mouse strains maintained at the central institute for experimental animals. in the first survey, 11 strains of mouse, which were 8 weeks of age or older and were kept in separate cages in the same animal room, were tested for antibodies to salmonella enteritidis, corynebacterium kutscheri, tyzzer's organisms, mycoplasma pulmonis, mouse hepatitis virus (mhv), sendai virus (hvj), pneumonia virus of mice (pvm) and minute virus o ...1978631200
studies on the immune response in chickens i. effect of various immunization procedures on the primary and secondary antibody responses to bovine serum albumin.antibody response and generation of immunological memory in chickens after stimulation by bovine serum albumin (bsa) were investigated. a single intravenous injection of bsa induced a relatively high primary antibody response but failed to generate definite memory for the secondary antibody response. variation in antigen dosage and the time interval between antigen injections did not affect significantly the levels of the primary and secondary antibody responses. the immunogenicity of deaggregat ...1978676427
[effects in the rat of a weak dose of acrolein inhaled continuously].the results of an experiment on 173 s. p. f. rats inhaling 0.55 ppm of acrolein, compared to 173 control rats, are reported. in what concerns the respiratory apparatus, this dose of acrolein affects its defense mechanisms, leading to a greater susceptibility to the airborne salmonella enteritidis infection, compared to the control group. these phenomena disappear spontaneously when intoxication is prolonged more than three weeks. on the contrary, the general toxic action, manifesting itself thro ...1975765136
fever: exchange of shivering by nonshivering pyrogenesis in cold-acclimated guinea pigs.the pyrogenic response of adult, unanesthetized guinea pigs to 2 mug/kg iv of salmonella enteritidis endotoxin was measured at 27 and 7 degrees c ambient temperatures, both before and after an 8-wk exposure to 7 degrees c. there were no significant differences between the onset, maximum height, and total duration of the fevers produced before and after cold acclimation in both thermal environments. however, in 27 degrees c, before cold acclimation, fever production was associated with vigorous s ...1976765315
effect of propranolol on endotoxin-induced pyrogenesis in newborn and adult guinea pigs.previous studied have shown that nonshivering thermogenesis (nst) is the prevailing mechanism of fever production in both newborn (during the first 2-3 wk of life) and adult cold-acclimated guinea pigs. this study was undertaken to determine whether this process may be mediated by noradrenergic sympathetics. the temperatures in the interscapular brown fat pad (tbat) and the colon (tre), the rate of oxygen consumption (vo2), and shivering activity were measured continuously for 5 h at 27 degrees ...1976765316
endotoxin toxicity in rats is enhanced by tilorone.the relatively nontoxic drug, tilorone, greatly enhanced the susceptibility of rats to lethal effects of endotoxin. the magnitude of the synergy was similar to that produced by adrenalectomy, but the effect of tilorone was not mediated by the adrenal glands. the histopathologic effects of endotoxin plus tilorone resembled those produced by much larger doses of endotoxin alone, including instances of the generalized shwartzman reaction.1976766017
[chemical and serological characterization of salmonella lipopolysaccharides from different phases of growth (author's transl)].chemical and serological investigations were carried out on lipopolysaccharides of 4 salmonella s-forms and of 1 sr-mutant, extracted from bacteria at different ages of culture (early exponential to stationary growth phase). the results show that the fatty acid composition of lipid a (lauric-, myristic-, palmitic-, and beta-hydroxy-myristic acids) does not undergo any significant change during the growth of the cultures. however, there are differences in the molar ratios of the fatty acids from ...1975766501
febrile illnesses resulting in hospital admission: a bacteriological and serological study in jakarta, indonesia.a study of 741 indonesian patients with fever was carried out in order to determine what serious febrile illnesses are prevalent in jakarta. all patients were hospitalized primarily because of fever and were studied by bacteriological and serological methods. bacteremia due to salmonella typhi (150 cases), s. enteritidis (36 cases), or both (2 cases) was common in both children and adults. one s. enteritidis isolate was chloramphenicol resistant. serological evidence of salmonella infection was ...1976769571
failure of endotoxin to increase nonspecific resistance to infection of lipopolysaccharide low-responder mice.in vitro and in vivo responses to lipopolysaccharide (lps) and various other bacterial immunostimulants were compared in c3h/he low-responder mice. the principal findings were as follows. (i) their splenic lymphocytes were stimulated by various gram-negative mitogens such as an escherichia coli peptidoglycan, a detoxified derivative of lps, and even endotoxins extracted by trichloroacetic acid that are known to contain protein; spleen cells of these mice were also transformed by two other b-cell ...1976773822
immunosuppressive effect of bacterial lipopolysaccharide on antibody response.injection of endotoxins (bacterial lipopolysaccharide: lps) several days prior to immunization causes the suppression of antibody response. the supressive effects of several kinds of lps preparations on the plaque-forming cell (pfc) antibody response in the spleen of mice were examined after immunization with sheep red blood cells (srbc). glycolipids obtained from heptoseless mutants(reform) of salmonella or its lipid a preparation coupled artificially with bovine serum albumin (bsa) are capable ...1976775151
[some epidemiological and microbiological aspects of food poisoning due to salmonellae]. 1975775228
induction of generalized shwartzman reaction(gsr) in irradiated rabbits by a single injection of endotoxin. 1976775679
salmonella in horses: a source of contamination of horsemeat in a packing plant under federal inspection.cecal samples from 270 slaughter horses revealed that 41 samples (15.1%) contained salmonella. of 233 horsemeat samples tested, salmonella was isolated from 62 samples, or 26.6%. only 2 of 158 human stool specimens from the plant workers revealed salmonella. predominant serotypes isolated from the horsemeat were salmonella enteritidis good and anatum, whereas the serotypes agona and derby predominated the horse cecal isolates. preliminary data indicate that the high percentage of meat contaminat ...1976776084
role of host factors in the pathogenesis of salmonella-associated arthritis in rats.to evaluate the roles of the infectious agent and the host in the pathogensis of salmonella-associated arthritis (saa), 1o(3) to 10(6) heat-killed salmonella enteritidis were injected directly into involved carpal joints in normal and actively immunized rats and in hosts adoptively immunized by the intravenous transfer of spleen cells from syngeneic donors with ongoing saa. as many as 10(6) living salmonellae invariably failed to generate more than a transient inflammatory response in normal rat ...1976776830
[induced filament formation in salmonella enteritidis by means of sodium chloride].induced morfological variations of bacteria by means of different agents has been known for many years. in this study the influence of sodium chloride on filament formation of s. enteritidis is studied, and the concentrations between 5-7% has been found effective in filament formation.1976778550
transformation of escherichia coli by r404 factor dna and properties of the transformants.three r-determinants (cb cm cf) out of eight present in r404 factor were transferred in transformation of escherichia coli by the plasmid dna isolated from minicells. the r-determinants acquired in this way formed the replicon tr404-1 and were untransferable by conjugation unless another self-transmissible plasmid was present in recipient. the evidences are presented in support of hypothesis that the transfer events consist in infection of transformant cells with sex factor, recombination betwee ...1976779405
salmonella enteritidis infection in rats: antigens involved in cell-mediated immunity.when rats are sub-lethally infected with s. entertidis by the intravenous route, there is a period of at least 14 days in which peritoneal exudate cells are unable to migrate from capillary tubes on to glass surfaces; thereafter they migrate as do macrophages from normal animals. the migration of peritoneal cells from rats infected 18-21 days previously is inhibited by lipopolysaccharide (lps) prepared from homologous and heterologous strains of salmonella. the apparent non-specificity of lps ac ...1975779743
adhesive properties of vibrio cholerae: nature of the interaction with intact mucosal surfaces.two companion papers in this series have characterized the interaction between vibrio cholerae and the surfaces of eukaryotic cells. the present paper reports studies of the association between vibrios or salmonella enteritidis and intact slices of intestinal tissue. a significant number of differences were noted in the characteristics of bacterial adhesion in these systems. the results are interpreted to indicate the presence of at least two receptors for vibrio adhesion on the mucosal surface ...1976780274
[resistance of the salmonella used for deratization to some environmental factors]. 1976783016
[influence of mutation in the gene-suppressor su-str on the virulence of salmonella enteritidis].virulent and avirulent cells resistant to streptomycin were revealed in the population of avirulent streptomycin-resistant mutant (obtained from the supressor revertant str-d s. enteritidis mutant) in seeding on a medium with streptomycin. transduction analysis of the isolated avirulent and virulent strains demonstrated that mutation in the gene-suppressor su-str+ led to the loss of virulence. in connection with the presence in the genom of suppressor revertants of the streptomycin-dependent mut ...1976785903
bioassay of endotoxin clearance in vivo and by perfused rat liver.endotoxin clearances in vivo and by the isolated perfused rat liver were evaluated via bioassay in lead-sensitized rats. a linear relationship between the probit of shock lethality and the endotoxin dose in the probit range of 4-6 was validated. endotoxin clearance in normal, fed rats displayed a linear relationship between the logarithm of the blood endotoxin concentration and time throughout the period of 15-240 min at doses of 500 and 1,000 mug/ rat; the half-time values were 58-63 min. decre ...1976786043
hypoglycemic depression of res function.the intravascular removal rates of colloidal carbon and of biologically active endotoxin by the reticuloendothelial system (res) were evaluated as a function of blood-glucose levels. there was a significant negative correlation of carbon clearance half time on blood glucose in both saline-treated and insulin-treated rats. insulin hypoglycemia depressed res carbon clearance with the maximal effect occurring at blood glucose values below 30 mg/dl. insulin hypoglycemia also severely impaired the in ...1976786044
salmonella food poisoning from turkeys: a combined medical veterinary investigation. 1976786953
adjuvant action of capsular polysaccharide of klebsiella pneumoniae on antibody response. v. further biological properties of the active substance.the neutral fraction (neutral cps-k) of klebsiella pneumoniae capsular polysaccharide (cps-k) from type 1, kasuya strain, has already been reported as the active substance responsible for the strong adjuvant effect of cps-k. the present results demonstrate that neutral cps-k exhibits further common biological activities with lipopolysaccharide (lps) isolated from salmonella enteritidis. the intensity of the lethality in mice of neutral cps-k by the intraperitoneal route is very similar to that o ...1976787603
phage typing system for salmonella enteritidis.a system is described for the phage typing of salmonella enteritidis. the system was developed using a number of bacteriophages that were isolated from sewage.1976788636
[induced filament formation in s. enteritidis by means of different sodium and chloride salts and different carbohydrates].we have previously observed filament formation in s. enteritidis which grew on media containing different salts and carbohydrates. in this study, sodium citrate, sod. carbonate, sod. molybdate, sod. acetate, sod. sulfate, potassium chloride, calcium chloride, saccharose and glucose were used as inducing agents. different concentrations of most of the above substances were effective in filament formation in s. enteritidis. temperature (37 degrees c and room temperature), ph of media and state of ...1976790103
[comparison of various aspects of normal and filament forms of s. enteritidis iv].induced filament formation of s. enteritidis by means of sodium chloride was previously reported. in this study various aspects of normal and filament forms of s. enteritidis are compared. filament forms had lost some of their biochemical activities when compared with the normal forms of s. enteritidis. there was no serological difference between the two forms. we were unable to show any difference in antibiotic sensitivity, because concentrated sodium chloride inhibited cell growth. no differen ...1976790106
[post-salmonellosis rheumatism].reports of forty-six cases of aseptic polyarthritis following intestinal salmonlla infections have been published. the organism involved is always a "minor" salmonella either typhimurium or enteritidis. the interval separating the diarrhoea from the joint manifestations is usually one or two weeks. post-salmonellosis rheumatism is most frequently polyarthritis involving the large joints accompanied by fever that is sometimes high. the sedimentation rate is increased and hyperleucytosis and discr ...1976790532
effect of capsular polysaccharide of klebsiella pneumoniae on host resistance to bacterial infections. ii. effects on peritoneal leukocytes of normal mice and mice infected with virulent salmonella enteritidis.in normal mice, the total count of peritoneal leukocytes was markedly decreased after intraperitoneal (i.p.) injection of the capsular polysaccharide of klebsiella pneumoniae (cps-k) depending on the dosage injected. this decrease was mainly due to the depletion of macrophages, and a decrease in the number of lymphocytes occurred to a lesser extent. cps-k in relatively smaller doses mobilized polymorphonuclear neutrophilic leukocytes (pmn) into the peritoneal fluid but it decreased them transien ...1976792533
ineffectiveness of lipopolysaccharide for preventing the tolerance induction in bone marrow-derived lymphoid cells with dinitrophenyl-poly-l-(glutamic acid, lysine).the effect of endotoxin or lipopolysaccharide (lps) on tolerance induction in bone marrow-derived lymphoid cells (b cells) was investigated. dinitrophenylated amino acid copolymer-l-(glutamic acid, lysine) (dnp-gl) acts as a potent tolerogen on normal and dnp-primed b cells. lps significantly enhanced the anti-sheep red blood cell plaque-forming cell (anti-srbc pfc) response that occurred after the immunization with a low dose of srbc. lps did not induce the primary anti-dnp pfc response after t ...1976792534
agglutination with o antisera of salmonella exposed to antibiotics.five strains of salmonella were grown on agar containing subinhibitory concentrations of ampicillin, gentamicin, tetracycline, or chloramphenicol, and on drug-free agar (control). antigens were prepared by heating bacteria suspensions in saline solution at 100 c or by suspension in alcohol. antigens were tested for agglutinability with somatic o antisera and fluorescent antibody staining. the alcohol-treated antigens prepared from organisms grown in the presence of antibiotics other than ampicil ...1976793377
microbial formation of nitrosopyrrolidine from nitrosoproline.the fate of orally administered npro was determined in rats. unchanged npro could be recovered in the urine, while npy was detected in the faeces of two of three rats tested. after successive administration of npro to the same rats, their intestinal contents were inoculated into media containing npro to test for npy formation. decarboxylation of npro occurred in the faeces cultures from those rats whose faeces had contained npy. when the faeces from 10 mice were inoculated into the npro media, a ...1976793983
Displaying items 101 - 200 of 6195