Publications

isolation and characterization of a novel dicistrovirus associated with moralities of the great freshwater prawn, macrobrachium rosenbergii.	the giant freshwater prawn, macrobrachium rosenbergii, is an economically important crustacean and is farmed in many countries. since 2009, a larval mortality syndrome of m. rosenbergii has broken out and spread widely in the main breeding area, including zhejiang, jiangsu, guangxi, and guangdong provinces in mainland china. a novel virus, named macrobrachium rosenbergii taihu virus (mrtv), was isolated from the moribund larvae and was determined to be the causative agent of the m. rosenbergii l ...	2016	26848659
ensemble cryo-em uncovers inchworm-like translocation of a viral ires through the ribosome.	internal ribosome entry sites (iress) mediate cap-independent translation of viral mrnas. using electron cryo-microscopy of a single specimen, we present five ribosome structures formed with the taura syndrome virus ires and translocase eef2•gtp bound with sordarin. the structures suggest a trajectory of ires translocation, required for translation initiation, and provide an unprecedented view of eef2 dynamics. the ires rearranges from extended to bent to extended conformations. this inchworm-li ...	2016	27159452
a novel method of real-time reverse-transcription loop-mediated isothermal amplification developed for rapid and quantitative detection of a new genotype (yhv-8) of yellow head virus.	a new genotype of yellow head virus (yhv), designated as yhv-8, was found in farmed shrimp fenneropenaeus chinensis suffering suspectedly from ems/ahpns (early mortality disease/acute hepatopancreatic necrosis disease) in china in 2012. in this study, a one-step, real-time reverse-transcription loop-mediated isothermal amplification (rrt-lamp) assay was developed for better detection of both genotypes of yhv-1 and yhv-8. a set of six specific primers was successfully designed targeting a conserv ...	2016	27221155
ictv virus taxonomy profile: dicistroviridae.	dicistroviridae is a family of small non-enveloped viruses with monopartite, linear, positive-sense rna genomes of approximately 8-10 kb. viruses of all classified species infect arthropod hosts, with some having devastating economic consequences, such as acute bee paralysis virus in domesticated honeybees and taura syndrome virus in shrimp farming. conversely, the host specificity and other desirable traits exhibited by several members of this group make them potential natural enemies for inten ...	2017	28366189