Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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| canine and feline vector-borne diseases in italy: current situation and perspectives. | in italy, dogs and cats are at risk of becoming infected by different vector-borne pathogens, including protozoa, bacteria, and helminths. ticks, fleas, phlebotomine sand flies, and mosquitoes are recognized vectors of pathogens affecting cats and dogs, some of which (e.g., anaplasma phagocytophilum, borrelia burgdorferi, dipylidium caninum, leishmania infantum, dirofilaria immitis, and dirofilaria repens) are of zoonotic concern. recent studies have highlighted the potential of fleas as vectors ... | 2010 | 20145730 |
| biogeography of tick-borne bhanja virus (bunyaviridae) in europe. | bhanja virus (bhav) is pathogenic for young domestic ruminants and also for humans, causing fever and affections of the central nervous system. this generally neglected arbovirus of the family bunyaviridae is transmitted by metastriate ticks of the genera haemaphysalis, dermacentor, hyalomma, rhipicephalus, boophilus, and amblyomma. geographic distribution of bhav covers southern and central asia, africa, and southern (partially also central) europe. comparative biogeographic study of eight know ... | 2010 | 20182535 |
| potential role of ticks as vectors of bluetongue virus. | when the first outbreak of bluetongue virus serotype 8 (btv8) was recorded in north-west europe in august 2006 and renewed outbreaks occurred in the summer of 2007 and again in 2008, the question was raised how the virus survived the winter. since most adult culicoides vector midges are assumed not to survive the northern european winter, and transovarial transmission in culicoides is not recorded, we examined the potential vector role of ixodid and argasid ticks for bluetongue virus. four speci ... | 2010 | 20358393 |
| characterization of the substrate specificity of human carboxypeptidase a4 and implications for a role in extracellular peptide processing. | cpa4 (carboxypeptidase a4) is a member of the metallocarboxypeptidase family. cpa4 was originally found in a screen of mrnas up-regulated by sodium butyrate-induced differentiation of cancer cells. further studies suggested a relation between cpa4 and prostate cancer aggressiveness. in the present study, we determined that cpa4 is secreted from cells as a soluble proenzyme (pro-cpa4) that can be activated by endoproteases, such as trypsin. three complementary approaches were used to study the su ... | 2010 | 20385563 |
| human anaplasmosis and anaplasma ovis variant. | 2010 | 20507768 | |
| prevalence of tick-borne pathogens in ticks in sicily. | the prevalence of anaplasma, ehrlichia, rickettsia and babesia/theileria species was analysed in questing and feeding adult ticks in sicily. a total of 678 ticks were collected and analysed in this study. of these, 29 were questing ticks and 649 were collected from infested cattle, sheep, goats or dogs. tick species analysed included rhipicephalus bursa, r. turanicus, r. sanguineus, hyalomma lusitanicum, h. marginatum, dermacentor marginatus, ixodes ricinus, r. (boophilus) annulatus and haemaphy ... | 2010 | 20537102 |
| ixodid ticks (acari: ixodidae) infesting humans in tokat province of turkey: species diversity and seasonal activity. | ixodid ticks (acari: ixodidae) are the major vectors of pathogens threatening animal and human health. tokat province, turkey, is a suitable habitat for extended tick activity with its moderate climate and vegetation. in the present study, we surveyed humans visiting health centers to determine the species diversity, geographical distribution, and seasonal activity of ixodid ticks infesting them. out of 5,999 adult ticks collected from humans from april to september, 2008, 800 ticks were identif ... | 2010 | 20618665 |
| application of highly sensitive saturation labeling to the analysis of differential protein expression in infected ticks from limited samples. | abstract: | 2010 | 20704695 |
| ticks infesting the endangered italian hare (lepus corsicanus) and their habitat in an ecological park in southern italy. | the italian hare (lepus corsicanus) is an endangered species whose natural populations have decreased in recent years. this study's objective was to identify ticks infesting hares and their habitats in a wildlife reserve in southern italy. in june 2009, ticks were collected by dragging in three transects set in a meadow habitat within an enclosure inhabited by hares and in three similar transects outside this enclosure. fifty-five ticks were collected by dragging, being 54 inside and 1 outside t ... | 2011 | 20711803 |
| flexibility of the thrombin-activatable fibrinolysis inhibitor pro-domain enables productive binding of protein substrates. | we have previously reported that thrombin-activatable fibrinolysis inhibitor (tafi) exhibits intrinsic proteolytic activity toward large peptides. the structural basis for this observation was clarified by the crystal structures of human and bovine tafi. these structures evinced a significant rotation of the pro-domain away from the catalytic moiety when compared with other pro-carboxypeptidases, thus enabling access of large peptide substrates to the active site cleft. here, we further investig ... | 2010 | 20880845 |
| pathogens and symbionts in ticks: a survey on tick species distribution and presence of tick-transmitted micro-organisms in sardinia, italy. | a total of 1485 adult ticks were collected from mammalian hosts in south-eastern sardinia, italy, during the years 2007-2008. ticks were identified and tested by pcr analysis for presence of rickettsia species of the spotted fever group, ehrlichia canis, anaplasma phagocytophilum, coxiella burnetii, bartonella species and leishmania species. among all tick species examined (rhipicephalus sanguineus, rhipicephalus turanicus, rhipicephalus bursa, rhipicephalus pusillus, hyalomma marginatum margina ... | 2010 | 20884769 |
| ixodid ticks in bosnia and herzegovina. | ticks of the ixodidae family represent an enormous threat to human and animal health. from january to december 2004, a total of 10,050 ixodid ticks were collected from 26 areas in bosnia and herzegovina and determined to the species level. ticks were collected from dogs, sheep, cows, goats, rodents, humans and plants. ixodes ricinus was the most prevalent species, followed by dermacentor marginatus marginatus, rhipicephalus bursa, hyalomma marginatum marginatum, rhipicephalus sanguineus, haemaph ... | 2010 | 20967487 |
| crimean-congo hemorrhagic fever in european part of turkey: genetic analysis of the virus strains from ticks and a seroepidemiological study in humans. | abstract a survey of ticks from domestic ruminants, together with a serosurvey in humans was conducted in thrace (northwestern turkey) to evaluate the prevalence of crimean-congo hemorrhagic fever virus (cchfv) in ticks and humans. more prevalent ticks were hyalomma marginatum, hyalomma aegyptium, rhipicephalus bursa, and rhipicephalus (boophilus) annulatus, with low numbers of dermacentor marginatus, rhipicephalus sanguineus group, and ixodes ricinus. no differences in the tick faunal compositi ... | 2010 | 21028961 |
| detection of babesia and theileria species infection in cattle from portugal using a reverse line blotting method. | babesiosis and theileriosis are tick-borne diseases widespread in tropical and sub-tropical regions with high economic impact worldwide. in portugal there are at least 4 tick vectors known to be competent for the transmission of babesia and theileria sp. identified: rhipicephalus bursa, rhipicephalus (boophilus) annulatus, ixodes ricinus and haemaphysalis punctata. all these potential babesia and theileria tick vectors are widely distributed in portugal, although they are predominant in the sout ... | 2010 | 21036481 |
| crimean-congo hemorrhagic fever virus, northeastern greece. | 2011 | 21192882 | |
| species diversity of ixodid ticks feeding on humans in amasya, turkey: seasonal abundance and presence of crimean-congo hemorrhagic fever virus. | ticks (acari:ixodidae) are important pests transmitting tick-borne diseases such as crimean-congo hemorrhagic fever (cchf) to humans. between 2002 and 2009, numerous cchf cases were reported in turkey, including amasya province. in the current study, species diversity, seasonal abundance of ticks, and presence of cchf virus (cchfv) in ticks infesting humans in several districts of amasya province were determined. in the survey, a total of 2,528 ixodid ticks were collected from humans with tick b ... | 2011 | 21337953 |
| tick-borne bacteria in mouflons and their ectoparasites in cyprus. | the cypriot mouflon (ovis orientalis ophion), a once almost extirpated species of wild sheep, is under strict surveillance because it can be threatened by likely transmission of pathogenic bacteria, such as anaplasma spp., rickettsia spp., and coxiella burnetii, primarily from domestic ungulates. we collected 77 blood samples from cypriot mouflons and 663 of their ectoparasites (rhipicephalus turanicus, rhipicephalus sanguineus, rhipicephalus bursa, hyalomma anatolicum excavatum, hyalomma margin ... | 2011 | 21441182 |
| the hard-tick fauna of mainland portugal (acari: ixodidae): an update on geographical distribution and known associations with hosts and pathogens. | this work is an updated revision of the available information on portuguese ixodid tick species. it includes data on tick biology, ecology, taxonomy and host/pathogen-associations. the current list of portuguese ixodid ticks comprises twenty species: dermacentor marginatus (sulzer, 1776), dermacentor reticulatus (fabricius, 1794), haemaphysalis hispanica gil collado, 1938, haemaphysalis inermis birula, 1895, haemaphysalis punctata canestrini & fanzago, 1878, hyalomma lusitanicum koch, 1844, hyal ... | 2011 | 21452063 |
| detection of new francisella-like tick endosymbionts in hyalomma spp. and rhipicephalus spp. (acari: ixodidae) from bulgaria. | we report on the identification of two new francisella-like endosymbionts (fles) found in three different tick species from bulgaria. the fles were characterized by 16s rrna and tul4 gene sequencing and seem to lack the molecular marker rd1. these two new taxa seem to be facultative secondary endosymbionts of ticks. | 2011 | 21705542 |
| ixodid ticks of road-killed wildlife species in southern italy: new tick-host associations and locality records. | the present study aimed to identify ticks collected from road-killed wildlife species retrieved in several localities of southern italy and to assess the presence of borrelia burgdorferi sensu lato, anaplasma phagocytophilum and rickettsia spp. dna in ticks. collections were carried out from january 2000 to december 2009 on wild animals found dead within the territories of 11 municipalities from three regions (i.e., apulia, basilicata, and calabria). in total, 189 carcasses of wild animals belon ... | 2011 | 21728058 |
| crimean-congo hemorrhagic fever virus in ticks collected from humans, livestock, and picnic sites in the hyperendemic region of turkey. | abstract during june and july 2007, about 3125 adult ticks were collected from humans, animals, and vegetation in a hyperendemic region (sivas and tokat) of turkey. a total of 2193 ticks were pooled in 225 pools and screened for the crimean congo hemorrhagic fever virus (cchfv) presence by antigen-capture enzyme-linked immunosorbent assay. infection rates were calculated as the maximum likelihood estimation with 95% confidence intervals (ci). the dominant tick species was found to be hyalomma ma ... | 2011 | 21736490 |
| evaluation of surrogate animal models of melioidosis. | burkholderia pseudomallei is the gram-negative bacterial pathogen responsible for the disease melioidosis. b. pseudomallei establishes disease in susceptible individuals through multiple routes of infection, all of which may proceed to a septicemic disease associated with a high mortality rate. b. pseudomallei opportunistically infects humans and a wide range of animals directly from the environment, and modeling of experimental melioidosis has been conducted in numerous biologically relevant mo ... | 2010 | 21772830 |
| species diversity and geographic distribution of hard ticks (acari: ixodoidea: ixodidae) infesting domestic ruminants, in qazvin province, iran. | this report presents the results of the first faunistic study of hard ticks in qazvin province of iran. the primary objective was to determine the species diversity and geographic distribution of hard ticks that parasitize domestic ruminants. information about the abiotic preferences of these species has been provided. a total of 286 cattle, 1,053 goats, and 2,050 sheep were examined in 13 villages in 28 flocks distributed throughout the studied areas. total direct body collections of ticks were ... | 2011 | 21805220 |
| New insights into the epidemiology of bovine piroplasmoses in Italy. | Few studies have been published on bovine piroplasmoses in Italy, and therefore a clear picture of the epidemiology of these infections is difficult to obtain. Vertebrate and invertebrate hosts in Central and Northern Regions of Italy were investigated in 2005 and 2006, when microscopy, molecular tools and serological tests were applied to 468 blood samples drawn from cattle in order to evaluate the presence of these protozoa and identify possible risk factors. Ticks were also collected, identif ... | 2011 | 21864982 |
| Species distribution and detection of Crimean Congo Hemorrhagic Fever Virus (CCHFV) in field-collected ticks in Ankara Province, Central Anatolia, Turkey. | Ticks may act as vectors for a number of infectious diseases including Crimean Congo Hemorrhagic Fever (CCHF). The causative agent is Crimean Congo Hemorrhagic Fever Virus (CCHFV), a member of Bunyaviridae, causing extensive ecchymosis, visceral bleeding and hepatic dysfunction with a high fatality rate in the affected individuals. CCHF was initially recognized in Turkey in 2002 and the current number of reported cases exceeds 4,400. This study was conducted to confirm the presence of tick speci ... | 2012 | 21910017 |
| spotted fever group rickettsiae in ticks collected from wild animals in israel. | we report molecular evidence for the presence of spotted fever group rickettsiae (sfgr) in ticks collected from roe deer, addax, red foxes, and wild boars in israel. rickettsia aeschlimannii was detected in hyalomma marginatum and hyalomma detritum while rickettsia massiliae was present in rhipicephalus turanicus ticks. furthermore, a novel uncultured sfgr was detected in haemaphysalis adleri and haemaphysalis parva ticks from golden jackals. the pathogenicity of the novel sfgr for humans is unk ... | 2011 | 22049050 |
| Crimean-Congo hemorrhagic fever virus in various ixodid tick species from a highly endemic area. | Ticks are major vectors of numerous diseases affecting animals and humans. Presence of various tick-borne pathogens such as Crimean-Congo hemorrhagic fever virus (CCHFV) in various tick species was documented. CCHF is a severe tick-borne illness caused by the CCHFV which is a member of the Nairovirus genus (family: Bunyaviridae). Presence of CCHFV was shown in the most prevalent ixodid tick species such as Hyalomma marginatum and Rhiphicephalus bursa in Turkey. In the present study, prevalence a ... | 2011 | 22119389 |
| first molecular detection of theileria ovis in rhipicephalus sanguineus tick in iran. | to determine tick infestation of domestic ruminants and their infection to ovine theileriosis in northern iran. | 2012 | 22182639 |
| a deep insight into the sialotranscriptome of the gulf coast tick, amblyomma maculatum. | saliva of blood sucking arthropods contains compounds that antagonize their hosts' hemostasis, which include platelet aggregation, vasoconstriction and blood clotting; saliva of these organisms also has anti-inflammatory and immunomodullatory properties. perhaps because hosts mount an active immune response against these compounds, the diversity of these compounds is large even among related blood sucking species. because of these properties, saliva helps blood feeding as well as help the establ ... | 2011 | 22216098 |
| serological evaluation of crimean-congo hemorrhagic fever in humans with high-risk professions living in enzootic regions of isfahan province of iran and genetic analysis of circulating strains. | crimean-congo hemorrhagic fever (cchf) is a zoonotic viral disease that is asymptomatic in infected livestock, but causes a serious threat to humans with a mortality rate up to 50%. although the cchf virus (cchfv) is often transmitted by ticks, livestock-to-human and human-to-human transmission also occurs. in the current study, we focused on cchf in the province of isfahan, located in the center of iran and deemed to be the second most infected province. human and livestock sera and resident ti ... | 2012 | 22217167 |
| crystal structure of novel metallocarboxypeptidase inhibitor from marine mollusk nerita versicolor in complex with human carboxypeptidase a4. | nvci is a novel exogenous proteinaceous inhibitor of metallocarboxypeptidases from the marine snail nerita versicolor. the complex between human carboxypeptidase a4 and nvci has been crystallized and determined at 1.7 å resolution. the nvci structure defines a distinctive protein fold basically composed of a two-stranded antiparallel β-sheet connected by three loops and the inhibitory c-terminal tail and stabilized by three disulfide bridges. nvci is a tight-binding inhibitor that interacts with ... | 2012 | 22294694 |
| molecular and biomorphometrical identification of ovine babesiosis in iran. | ovine babesiosis is the most important haemoparasitic tick-borne disease of small ruminants in iran caused by babesia ovis, b. motasi, and b. crassa. the aim of this study was to characterize the species of ovine babesia species isolated from different geographical region of iran. | 0 | 22347262 |
| a survey of ixodid ticks feeding on cattle and prevalence of tick-borne pathogens in the black sea region of turkey. | the study reports the frequency of infestation and the prevalence of tick-borne pathogens in feeding adult ticks detached from cattle in two climatic zones of the black sea region of turkey. a total of 2160 adult ticks were collected during 2007-2008. of these, 1062 were randomly selected, divided into 224 pools, and tested for the presence of bovine theileria, babesia, and anaplasma species. eleven tick species were recognized on cattle in the study. hyalomma marginatum was widely disrubuted in ... | 2012 | 22365338 |
| tri-domain bifunctional inhibitor of metallocarboxypeptidases a and serine proteases isolated from marine annelid sabellastarte magnifica. | this study describes a novel bifunctional metallocarboxypeptidase and serine protease inhibitor (smci) isolated from the tentacle crown of the annelid sabellastarte magnifica. smci is a 165-residue glycoprotein with a molecular mass of 19.69 kda (mass spectrometry) and 18 cysteine residues forming nine disulfide bonds. its cdna was cloned and sequenced by rt-pcr and nested pcr using degenerated oligonucleotides. employing this information along with data derived from automatic edman degradation ... | 2012 | 22411994 |
| molecular detection of theileria spp. in sheep and vector ticks in the north khorasan province, iran. | a survey was carried in north khorasan province, iran in 2010-2011, designed to identify theileria spp. infections of both sheep and ticks. the tick species were also examined. ninety sheep from different flocks were clinically examined, and blood samples and ixodid ticks were collected. light microscopy of blood smears revealed theileria spp. infection in 37 (41.1 %), while 74 (82.2 %) of blood samples were positive using semi-nested pcr. theileria ovis, theileria lestoquardi, and mixed infecti ... | 2013 | 22791188 |
| association of environmental traits with the geographic ranges of ticks (acari: ixodidae) of medical and veterinary importance in the western palearctic. a digital data set. | we compiled information on the distribution of ticks in the western palearctic (11°w, 45°e; 29°n, 71°n), published during 1970-2010. the literature search was filtered by the tick's species name and an unambiguous reference to the point of capture. records from some curated collections were included. we focused on tick species of importance to human and animal health, in particular: ixodes ricinus, dermacentor marginatus, d. reticulatus, haemaphysalis punctata, h. sulcata, hyalomma marginatum, h ... | 2012 | 22843316 |
| molecular detection of theileria spp. and babesia spp. in sheep and ixodid ticks from the northeast of iran. | theilerioses and babesioses are important diseases in iranian sheep. the present study was undertaken to identify and classify/specify theileria spp. and babesia spp. in sheep and vector ticks. investigation was carried out from 2009 to 2011 in the khorasan razavi province, iran. in total, 302 sheep originating from 60 different flocks were clinically examined and their blood collected. in addition, from the same flocks, ixodid ticks were sampled. stained blood smears were microscopically examin ... | 2013 | 22924924 |
| rickettsia species in ticks removed from humans in istanbul, turkey. | a total of 167 ticks collected from humans in istanbul (turkey) in 2006 were screened for rickettsia species, and nested pcrs targeting glta and ompa rickettsial fragment genes were carried out. rickettsia monacensis (51), r. aeschlimannii (8), r. conorii subsp. conorii (3), r. helvetica (2), r. raoultii (1), r. africae (1), r. felis (1), and other rickettsia spp. (2), were detected. to our knowledge, these rickettsia species (except r. conorii) had never been reported in ticks removed from huma ... | 2012 | 22925016 |
| anaplasma phagocytophilum in horses and ticks in tunisia. | anaplasma phagocytophilum , the causative agent of granulocytic anaplasmosis, affects several species of wild and domesticated mammals, including horses. we used direct and indirect methods to compare and evaluate exposure to a. phagocytophilum in horses in northern tunisia. | 2012 | 22935132 |
| a survey of ectoparasite infestation in dogs in tehran, iran. | this survey was conducted to identify and estimate the frequencies of ectoparasites of dogs in tehran, iran. a total of 143 dogs attended at the small animal hospital of the veterinary school, the university of tehran, were examined for the presence of ectoparasites and dermatological lesions. ectoparasite specimens and blood samples were sent to parasitology and hematology laboratories, respectively. ticks were the most frequent ectoparasite (36.4%, 52/143), followed by fleas (29.4%, 42/143), m ... | 2012 | 23070452 |
| first detection of ehrlichia canis in rhipicephalus bursa ticks in sardinia, italy. | canine monocytic ehrlichiosis is a common and widespread disease. this disease is present in sardinia year-round because the temperate weather on the island permits the survival of many types of tick vectors. a total of 35 ticks was collected from goats in south-eastern sardinia, italy, and tested for ehrlichia dna using polymerase chain reaction and dna sequencing. this study provides the first evidence of the presence of ehrlichia canis in rhipicephalus bursa ticks. the data presented here inc ... | 2012 | 23140896 |
| rickettsia slovaca from dermacentor marginatus ticks in sardinia, italy. | nineteen ticks belonging to the species dermacentor marginatus, rhipicephalus bursa, and haemaphysalis sulcata were collected from wild animals (wild boar, deer, and mouflon) in south-western sardinia, italy. five d. marginatus ticks from wild boar were pcr-positive when analyzed using glta-specific and ompa-specific primers, leading to the identification and first isolation in cell culture of rickettsia slovaca, the causative agent of tick-borne lymphadenopathy (tibola), on the island of sardin ... | 2012 | 23140897 |
| matrix-assisted laser desorption ionization-time of flight mass spectrometry for rapid identification of tick vectors. | a method for rapid species identification of ticks may help clinicians predict the disease outcomes of patients with tick bites and may inform the decision as to whether to administer postexposure prophylactic antibiotic treatment. we aimed to establish a matrix-assisted laser desorption ionization-time of flight mass spectrometry (maldi-tof ms) spectrum database based on the analysis of the legs of six tick vectors: amblyomma variegatum, rhipicephalus sanguineus, hyalomma marginatum rufipes, ix ... | 2013 | 23224087 |
| hard ticks (acari, ixodidae) of croatia. | the present paper is based on original and literature data. in croatia the first studies on the occurrence of ixodid species were made about 80 years ago. the number of tick species recorded in croatia considerably increased during the 1950s, 60s, 70s and 80s of the past century. a total of 21 species of hard tick belonging to 5 genera have been recorded in croatia. ixodes is the best represented genus, with seven species recorded. haemaphysalis is represented by six species, followed by rhipice ... | 2012 | 23372407 |
| the seasonal activity of ixodes ricinus tick in amol, mazandaran province, northern iran. | the present study aimed to demonstrate the seasonal activities of ixodes ricinus at the pasture level and on the host. | 2012 | 23378970 |
| species diversity and abundance of ticks in three habitats in southern italy. | a 2-year study was conducted from march 2010 to march 2012 in a forested area in southern italy to evaluate the species diversity and abundance of free-living ticks in 3 different habitats: (i) a meadow habitat within an enclosure inhabited by roe deer (capreolus capreolus); (ii) a man-made trail located in a high-altitude, forested area; and (iii) a grassland near a house inhabited by 3 people. in total, 10,795 ticks were collected. ixodes ricinus was the most abundant species (69.0%), followed ... | 2013 | 23403153 |
| molecular evidence for bacterial and protozoan pathogens in hard ticks from romania. | the aim of the present study was to provide a preliminary insight into the diversity of tick-borne pathogens circulating at the domestic host-tick interface in romania. for this, feeding and questing ticks were analyzed by real-time polymerase chain reaction (pcr) for the presence of anaplasma phagocytophilum, anaplasma platys, ehrlichia canis, borrelia burgdorferi sensu latu, and by pcr and subsequent sequencing for rickettsia spp., babesia spp. and theileria spp. a total of 382 ticks, encompas ... | 2013 | 23428204 |
| prevalence and genetic diversity of piroplasm species in horses and ticks from tunisia. | the genetic diversity and prevalence of babesia and theileria species in the equine population of tunisia were studied using reverse line blot (rlb) hybridization on blood samples and unfed adult ticks collected from apparently healthy horses from three bioclimatic zones in tunisia. piroplasms were identified in 13 of 104 of the horse blood samples analyzed (12.5%) and five genotype groups were identified: theileria equi group a (nine animals, 8.7%), group c (one animal, 1.0%) and group d (three ... | 2013 | 23542456 |
| first survey of hard ticks (acari: ixodidae) on cattle, sheep and goats in boeen zahra and takistan counties, iran. | to carry out the distribution survey of hard ticks of livestock in boeen zahra and takistan counties of qazvin province from april 2010 to september 2010. | 2012 | 23569956 |
| genetic analysis and epidemiology of crimean congo hemorrhagic fever viruses in baluchistan province of pakistan. | pakistan is considered as an endemic country for crimean-congo hemorrhagic fever with numerous outbreaks and sporadic cases reported during the past two decades. majority of cases are reported from baluchistan province with subsequent transmissions to non-endemic regions mainly through infected animals directly or via infested ticks. we hereby describe the molecular investigations of cchf cases reported during 2008 in quetta city of baluchistan province. | 2013 | 23641865 |
| single genotype of anaplasma phagocytophilum identified from ticks, camargue, france. | 0 | 23697386 | |
| spatial disaggregation of tick occurrence and ecology at a local scale as a preliminary step for spatial surveillance of tick-borne diseases: general framework and health implications in belgium. | the incidence of tick-borne diseases is increasing in europe. sub national information on tick distribution, ecology and vector status is often lacking. however, precise location of infection risk can lead to better targeted prevention measures, surveillance and control. | 2013 | 23800283 |
| sex-biased differences in the effects of host individual, host population and environmental traits driving tick parasitism in red deer. | the interactions between host individual, host population, and environmental factors modulate parasite abundance in a given host population. since adult exophilic ticks are highly aggregated in red deer (cervus elaphus) and this ungulate exhibits significant sexual size dimorphism, life history traits and segregation, we hypothesized that tick parasitism on males and hinds would be differentially influenced by each of these factors. to test the hypothesis, ticks from 306 red deer-182 males and 1 ... | 2013 | 23819112 |
| crimean-congo hemorrhagic fever in iran. | the presence of crimean-congo hemorrhagic fever virus (cchfv) in iran was first identified in studies of livestock sera and ticks in the 1970s, but the first human infection was not diagnosed until 1999. since that time, the number of cases of cchf in iran has markedly increased. through january 2012, articles in the published literature have reported a total of 870 confirmed cases, with 126 deaths, for a case fatality rate (cfr) of 17.6%. the disease has been seen in 26 of the country's 31 prov ... | 2013 | 23872313 |
| morphological and genetic diversity of rhipicephalus sanguineus sensu lato from the new and old worlds. | the taxonomic status of the brown dog tick (rhipicephalus sanguineus sensu stricto), which has long been regarded as the most widespread tick worldwide and a vector of many pathogens to dogs and humans, is currently under dispute. | 2013 | 23880226 |
| mediterranean spotted fever in southeastern romania. | although cases of mediterranean spotted fever (msf) have been reported for decades in southeastern romania, there are few published data. we retrospectively studied 339 patients, diagnosed with msf at the national institute of infectious diseases "prof. dr. matei bals" between 2000 and 2011, in order to raise awareness about msf in certain regions of romania. according to the raoult diagnostic criteria 171 (50.4%) had a score >25 points. mean age was 52.5 years. one hundred and fifty-five (90.6% ... | 2013 | 24024190 |
| a molecular study of tick-borne haemoprotozoan parasites (theileria and babesia) in small ruminants in northern tunisia. | in this study, the frequency of theileria and babesia species in sheep and goats was assessed via reverse line blotting (rlb). a total of 263 apparently healthy sheep and goats, from 16 randomly selected flocks located in 9 localities situated in 3 bioclimatic zones in tunisia, were investigated for the blood protozoans. rlb hybridization with polymerase chain reaction detected only theileria ovis in sheep and goats, accounting for 22.4% (95% confidence interval [ci]: 17.6-27.1%) positive sample ... | 2013 | 24029713 |
| prevalence of ixodid tick infestation of sheep in the arasbaran region of iran. | this survey was carried out in sheep herds of arasbaran region in northwest of iran. the aims of this survey were assessment of occurrence hard ticks on sheep in this region and speciation and identification of detached ticks from sheep. in addition determination of tick distribution on sheep body surface was studied. in this study 330 sheep were examined and ticks from infested animals were collected. in parasitological laboratory speciation of ticks were done by stereomicroscope and using of t ... | 2012 | 24082534 |
| comparative analysis of mitochondrial markers from four species of rhipicephalus (acari: ixodidae). | mitochondrial sequences of four mitochondrial markers: 12s rrna, 16s rrna, cytochrome c oxidase subunit i (cox1) and cytochrome b (cytb) from four rhipicephalus species were analyzed to establish genetic relationships and enable molecular identification. field-collected samples from the species rhipicephalus annulatus, rhipicephalus bursa, rhipicephalus sanguineus and rhipicephalus turanicus were amplified by pcr and compared with genbank™ annotated sequences. pcr products were obtained using pr ... | 2013 | 24091196 |
| update on tick-borne rickettsioses around the world: a geographic approach. | tick-borne rickettsioses are caused by obligate intracellular bacteria belonging to the spotted fever group of the genus rickettsia. these zoonoses are among the oldest known vector-borne diseases. however, in the past 25 years, the scope and importance of the recognized tick-associated rickettsial pathogens have increased dramatically, making this complex of diseases an ideal paradigm for the understanding of emerging and reemerging infections. several species of tick-borne rickettsiae that wer ... | 0 | 24092850 |
| comparative analyses of mitochondrial and nuclear genetic markers for the molecular identification of rhipicephalus spp. | the genus rhipicephalus (acari: ixodidae) comprises a large number of vectors of pathogens of substantial medical and veterinary concern; however, species identification based solely on morphological features is often challenging. in the present study, genetic distance within selected rhipicephalus species (i.e., rhipicephalus bursa, rhipicephalus guilhoni, rhipicephalus muhsamae, rhipicephalus sanguineus sensu lato and rhipicephalus turanicus), were investigated based on molecular and phylogene ... | 2013 | 24103336 |
| seasonal dynamics of tick species in an urban park of rome. | regular collections were obtained in the natural reserve of the insugherata of rome during 2011 in order to obtain the tick species composition and the respective seasonal dynamics of the area. a total of 325 ticks was collected in selected sites by means of drag sampling. among the identified species, rhipicephalus turanicus was the most abundant (72.3%), followed by ixodes ricinus (19.7%), dermacentor marginatus (6.5%), haemaphysalis punctata (1.2%), and rhipicephalus bursa (0.3%). r. turanicu ... | 2013 | 24140501 |
| detection of rickettsia in rhipicephalus sanguineus ticks and ctenocephalides felis fleas from southeastern tunisia by reverse line blot assay. | ticks (n = 663) and fleas (n = 470) collected from domestic animals from southeastern tunisia were screened for rickettsia infection using reverse line blot assay. evidence of spotted fever group rickettsia was obtained. we detected rickettsia felis in fleas, rickettsia massiliae bar 29 and the rickettsia conorii israeli spotted fever strain in ticks, and rickettsia conorii subsp. conorii and rickettsia spp. in both arthropods. the sensitivity of the adopted technique allowed the identification ... | 2013 | 24226919 |
| overexpression of multiple detoxification genes in deltamethrin resistant laodelphax striatellus (hemiptera: delphacidae) in china. | the small brown planthopper (sbph), laodelphax striatellus (fallén), is one of the major rice pests in asia and has developed resistance to multiple classes of insecticides. understanding resistance mechanisms is essential to the management of this pest. biochemical and molecular assays were performed in this study to systematically characterize deltamethrin resistance mechanisms with laboratory-selected resistant and susceptible strains of sbph. | 2013 | 24324548 |
| molecular and serological evidence for the circulation of the tick symbiont midichloria (rickettsiales: midichloriaceae) in different mammalian species. | the midichloriaceae is a novel family of the order rickettsiales, that encompasses intracellular bacteria associated with hard ticks (ixodidae) and other arthropods. the most intensively investigated member of this family is midichloria mitochondrii, a symbiotic bacterium of the sheep tick ixodes ricinus, characterized by the capacity of multiplying inside the mitochondria. a recent study suggested that these bacteria might be inoculated into the human host during the tick bite. the purpose of t ... | 2013 | 24330701 |
| [molecular-genetic characterization of the bhanja virus (bhav) and the razdan virus (razv) (bunyaviridae, phlebovirus) isolated from the ixodes ticks rhipicephalus bursa (canestrini and fanzago, 1878) and dermacentor marginatus (sulzer, 1776) in transcaucasus]. | two bunyaviruses, bhanja (bhav, leiv-az1818) isolated from the ixodes ticks rhipecephalus bursa (canestrini and fanzago, 1878) in azerbaijan (1973) and razdan (razv; strain leiv-arm2741) isolated from the dermacentor marginatus (sulzer, 1776) ticks in armenia (1972), were de novo sequenced (on the illumina platform). the amino acid identity between these viruses proteins were 95.8% (rdrp, l-segment), 90.3% (gngc, m-segment), and 92.5% (n, s-segment). thus, razv was classified to bhav group. gngc ... | 2016 | 24354060 |
| control of tick infestations and pathogen prevalence in cattle and sheep farms vaccinated with the recombinant subolesin-major surface protein 1a chimeric antigen. | despite the use of chemical acaricides, tick infestations continue to affect animal health and production worldwide. tick vaccines have been proposed as a cost-effective and environmentally friendly alternative for tick control. vaccination with the candidate tick protective antigen, subolesin (sub), has been shown experimentally to be effective in controlling vector infestations and pathogen infection. furthermore, escherichia coli membranes containing the chimeric antigen composed of sub fused ... | 2014 | 24398155 |
| detection of naturally infected vector ticks (acari: ixodidae) by different species of babesia and theileria agents from three different enzootic parts of iran. | diagnostic study of vector ticks for different pathogens transmitted specifically have been done by iranian old scientists working on the basis of biological transmission of pathogens. in this study we decided to confirm natural infection of different collected ticks from three different provinces of iran. | 2013 | 24409442 |
| a survey of ixodid tick species and molecular identification of tick-borne pathogens. | this study was undertaken in two different climatic areas of turkey to determine the presence of tick-borne pathogens of medical and veterinary importance. the ticks were removed from humans, pooled according to species and developmental stages, and analyzed by pcr, reverse line blot (rlb) and sequencing. of the 2333 removed ticks from 10 species, 1238 (53.06%) were obtained from the arid cold zone, and the remaining 1095 (46.93%) were obtained from the humid zone. the removed ticks were identif ... | 2014 | 24424312 |
| crimean-congo hemorrhagic fever virus, greece. | seroprevalence of crimean-congo hemorrhagic fever virus (cchfv) is high in some regions of greece, but only 1 case of disease has been reported. we used 4 methods to test 118 serum samples that were positive for cchfv igg by commercial elisa and confirmed the positive results. a nonpathogenic or low-pathogenicity strain may be circulating. | 0 | 24447877 |
| hard tick factors implicated in pathogen transmission. | ticks are the most common arthropod vector, after mosquitoes, and are capable of transmitting the greatest variety of pathogens. for both humans and animals, the worldwide emergence or re-emergence of tick-borne disease is becoming increasingly problematic. despite being such an important issue, our knowledge of pathogen transmission by ticks is incomplete. several recent studies, reviewed here, have reported that the expression of some tick factors can be modulated in response to pathogen infec ... | 2014 | 24498444 |
| assessment of exposure to piroplasms in sheep grazing in communal mountain pastures by using a multiplex dna bead-based suspension array. | piroplasms are tick-borne hemoprotozoans with a major impact on extensive management systems. detection of sub-clinical low-level carriers, which can act as source of infection for vector ticks, is key to protect livestock trade and facilitate preventive control programs. the purpose of this study was to develop a method for the detection of ovine piroplasms and to use it in a field study aimed at investigating piroplasms infection in semi-extensive production systems in the basque country (nort ... | 2013 | 24499621 |
| molecular and serological detection of theileria equi and babesia caballi infection in horses and ixodid ticks in iran. | equine piroplasmosis is a hemoprotozoan tick-borne disease with worldwide distribution that is caused by theileria equi and babesia caballi. however, the geographical distribution of equine piroplasmosis in iran is unknown. the aim of the current study was to determine the causative agents and vector ticks of equine piroplasmosis in horses in the north khorasan province. in the year 2011, 100 horses were randomly selected from 14 villages. blood samples and ixodid ticks were collected and examin ... | 2014 | 24556274 |
| retrospective study of hemoparasites in cattle in southern italy by reverse line blot hybridization. | tick-borne diseases are widespread in tropical and temperate regions and are responsible for important economic losses in those areas. in order to assess the presence and prevalence of various pathogens in southern italy, we retrospectively analyzed cattle blood samples collected for a previous study in 2000 using reverse line blot (rlb) hybridization. the study had been carried out in three regions of southern italy on 1,500 randomly selected and apparently healthy adult cattle. rlb showed that ... | 2014 | 24614604 |
| prevalence of piroplasms in small ruminants in north-west tunisia and the first genetic characterisation of babesia ovis in africa. | in this study, the prevalence of piroplasms in sheep and goats was assessed with giemsa-stained blood smear examination, pcr and nested pcr-restriction fragment length polymorphism (rflp) to identify babesia and theileria species, respectively, in 338 small ruminants (172 sheep and 166 goats) from three sites in north-west tunisia during the 2011 summer season. the overall infection prevalence of piroplasms in giemsa-stained blood smears was 3.2% (11/338), with a parasitaemia ranging from 0.01 t ... | 2014 | 24849588 |
| pcr-based detection of babesia ovis in rhipicephalus bursa and small ruminants. | this study aimed to assess the prevalence of babesia ovis infection in adult rhipicephalus bursa and small ruminants in west azerbaijan province, iran. blood samples were collected from 280 sheep and 122 goats of forty randomly selected flocks. specific b. ovis fragment was detected in 67 animals (16.7%), of which 52 animals (18.6%) were sheep and 15 animals (12.2%) goats (p < 0.05). of the 848 r. bursa collected from naturally infested small ruminants and farm dogs, babesia ovis was detected by ... | 2014 | 24876944 |
| a novel ap92-like crimean-congo hemorrhagic fever virus strain, greece. | ticks were collected from various regions of northern greece and tested for the presence of crimean-congo hemorrhagic fever virus (cchfv) rna. human and animal sera were collected in the regions where cchfv-positive ticks were detected, and they were tested for the presence of igg antibodies against the virus. a cchfv strain was detected in rhipicephalus bursa ticks collected from sheep in kastoria regional unit, differing by 9.7% at the nucleotide level from the ap92 strain, which was isolated ... | 2014 | 24953797 |
| a 24-48 h fed amblyomma americanum tick saliva immuno-proteome. | multiple tick saliva proteins, the majority of which are unknown, confer tick resistance in repeatedly infested animals. the objective of this study was to identify the 24-48 h fed amblyomma americanum tick saliva immuno-proteome. the 24-48 h tick-feeding phase is critical to tick parasitism as it precedes important events in tick biology, blood meal feeding and disease agent transmission. fed male, 24 and 96 h fed female phage display cdna expression libraries were biopanned using rabbit antibo ... | 2014 | 24962723 |
| molecular evidence for trans-stadial and transovarial transmission of babesia occultans in hyalomma marginatum and rhipicephalus turanicus in turkey. | a total of 1064 adult ticks identified as hyalomma marginatum (n=965), rhipicephalus turanicus (n=86), haemaphysalis inermis (n=9) and rhipicephalus bursa (n=4) along with 20 egg masses derived from h. marginatum (n=18) and r. bursa were screened for babesia occultans. the ticks were combined into 328 pools and infection rates were calculated as the maximum likelihood estimation (mle) with 95% confidence intervals (ci). of these pools, 23 (7%) were positive for b. occultans, and the overall mle ... | 2014 | 25002306 |
| spotted fever rickettsia species in hyalomma and ixodes ticks infesting migratory birds in the european mediterranean area. | a few billion birds migrate annually between their breeding grounds in europe and their wintering grounds in africa. many bird species are tick-infested, and as a result of their innate migratory behavior, they contribute significantly to the geographic distribution of pathogens, including spotted fever rickettsiae. the aim of the present study was to characterize, in samples from two consecutive years, the potential role of migrant birds captured in europe as disseminators of rickettsia-infecte ... | 2014 | 25011617 |
| ticks infesting humans in italy and associated pathogens. | ticks may transmit a large variety of pathogens, which cause illnesses in animals and humans, commonly referred to as to tick-borne diseases (tbds). the incidence of human tbds in italy is underestimated because of poor surveillance and the scant amount of studies available. | 2014 | 25023709 |
| prevalence of crimean-congo hemorrhagic fever virus antibodies in greek residents in the area where the ap92 strain was isolated. | crimean-congo hemorrhagic fever (cchf) is a viral disease with fatality rate up to 30%. up to date, only one cchf case has been reported in greece, while a distinct virus strain (ap92) had been isolated in 1975 from ticks in imathia prefecture, northern greece. the aim of the present study was to estimate the cchf virus (cchfv) seroprevalence among humans residing in the prefecture of imathia, and the neighboring prefecture of pella, and to investigate the risk factors associated with the seropo ... | 0 | 25031510 |
| role of migratory birds in spreading crimean-congo hemorrhagic fever, turkey. | we investigated migratory birds' role in spreading crimean-congo hemorrhagic fever virus (cchfv) through attached ticks. we detected cchfv rna in ticks on migratory birds in turkey. two isolates showed similarity with cchfv genotype 4, suggesting a role for ticks in cchfv epidemics in turkey and spread of cchfv by birds. | 0 | 25062428 |
| identification of tick-borne pathogens in ticks feeding on humans in turkey. | the importance of tick-borne diseases is increasing all over the world, including turkey. the tick-borne disease outbreaks reported in recent years and the abundance of tick species and the existence of suitable habitats increase the importance of studies related to the epidemiology of ticks and tick-borne pathogens in turkey. the aim of this study was to investigate the presence of and to determine the infection rates of some tick-borne pathogens, including babesia spp., borrelia burgdorferi se ... | 2014 | 25101999 |
| survey on cattle ticks in nur, north of iran. | to survey the prevalence of cattle ticks in nur county and prepare a list of tick fauna in this district. | 2014 | 25182439 |
| distribution of ticks (acari: ixodidae) infesting domestic ruminants in mountainous areas of golestan province, iran. | to determine the prevalence of ticks on cattle in the mountainous areas of golestan province and their geographical distribution. | 0 | 25183090 |
| a new multiple-locus variable-number tandem repeat analysis reveals different clusters for anaplasma phagocytophilum circulating in domestic and wild ruminants. | anaplasma phagocytophilum is a tick-borne intragranulocytic alpha-proteobacterium. it is the causative agent of tick-borne fever in ruminants, and of human granulocytic anaplasmosis in humans, two diseases which are becoming increasingly recognized in europe and the usa. however, while several molecular typing tools have been developed over the last years, few of them are appropriate for in-depth exploration of the epidemiological cycle of this bacterium. therefore we have developed a multiple-l ... | 2014 | 25228371 |
| crimean-congo hemorrhagic fever virus clades v and vi (europe 1 and 2) in ticks in kosovo, 2012. | despite being a small country, kosovo represents one of the few foci of crimean-congo hemorrhagic fever (cchf) in europe. the distribution of kosovar tick vectors and the evolution of cchf virus in ticks are both as yet unknown. a better description of the extent and the genetic diversity of cchfv in ticks from endemic settings is essential, in order to be controlled. we investigated the 2012 distribution of kosovar ticks alongside the prevalence and the phylogeography of tick-derived cchfv. hya ... | 2014 | 25255381 |
| molecular identification of theileria and babesia in ticks collected from sheep and goats in the black sea region of turkey. | a molecular survey was undertaken in the black sea region of turkey to determine the presence of theileria and babesia species of medical and veterinary importance. the ticks were removed from sheep and goats, pooled according to species and locations, and analyzed by pcr-based reverse line blot (rlb) and sequencing. a total of 2241 ixodid ticks belonging to 5 genus and 12 species were collected and divided into 310 pools. infection rates were calculated as the maximum likelihood estimation (mle ... | 2015 | 25260692 |
| molecular epizootiology and diagnosis of porcine babesiosis in sardinia, italy. | the recent characterization of the 18s ribosomal rna (rrna) of a pathogenic babesia species in a domestic sow paved the way for establishing diagnostic and epidemiological tools for porcine babesiosis. here, we developed the first specific babesia sp. suis pcr, and we applied this test to a panel of samples collected from animals living in a typical mediterranean environment (sardinia, italy), including domestic pigs, wild boars, and ticks. in domestic pigs, pcr coupled with sequencing revealed ... | 2014 | 25325315 |
| prevalence of ixodid ticks on cattle, sheep and goats in ilam county, ilam province, iran. | this survey was performed to find out the infestation rate of ixodidae ticks in domestic ruminants in ilam county during 21 march 2009 to 23 august 2009. sampling was performed in 25 villages and 15 animal farm from different areas of this county. a total of 1,316 ticks were collected from 416 cattle, 208 sheep and 147 goats. the overall prevalence of ticks was recorded: 43, 23.5, and 49/6 % in cattle, sheep, and goats respectively. the number of ticks that collected from cattle, sheep, and goat ... | 2013 | 25698857 |
| circulation of crimean-congo hemorrhagic fever virus in the former yugoslav republic of macedonia revealed by screening of cattle sera using a novel enzyme-linked immunosorbent assay. | there are only few assays available for the detection of crimean-congo hemorrhagic fever virus (cchfv)-specific antibodies in animals, and data about diagnostic sensitivity and specificity are incompletely documented for most of these tests. this is unfortunate since cchfv antibodies in animals can be used as indicator for virus circulation in a geographic area and therewith potential risk of human exposure. this paper therefore reports on a novel elisa for the detection of cchfv-specific antibo ... | 2015 | 25742017 |
| ectoparasite load in the crested porcupine hystrix cristata linnaeus, 1758 in central italy. | the crested porcupine hystrix cristata is a large body-sized rodent, occurring in europe only in the italian peninsula, where it may have been introduced in early medieval times. its parasite fauna is currently poorly known and limited to few anecdotal observations. we have analyzed the ectoparasite load of 165 crested porcupines from tuscany and latium (central italy). both captured and road-killed individuals were checked for fleas and ticks. overall, only 39 porcupines were infested by four s ... | 2015 | 25773184 |
| hard ticks (ixodidae) and crimean-congo hemorrhagic fever virus in south west of iran. | ticks are vectors of some important arthropod-borne diseases in both fields of veterinary and medicine, such as lyme, tularemia, rocky mountain spotted fever, and some types of encephalitis as well as crimean congo hemorrhagic fever (cchf). iran is known as one of the main foci of cchf in west of asia. this study was conducted in darrehshahr county because of the development of animal husbandry in this area to detect the fauna and viral infection of the hard ticks of livestock. a cross-sectional ... | 2015 | 25796025 |
| preliminary investigation on tick fauna in the neighborhood of tarquinia, lazio, italy. | this study represents a preliminary inquiry on tick fauna composition carried out in maremma, central italy, where very few data are available. | 2015 | 25857387 |
| the recent evolution of a maternally-inherited endosymbiont of ticks led to the emergence of the q fever pathogen, coxiella burnetii. | q fever is a highly infectious disease with a worldwide distribution. its causative agent, the intracellular bacterium coxiella burnetii, infects a variety of vertebrate species, including humans. its evolutionary origin remains almost entirely unknown and uncertainty persists regarding the identity and lifestyle of its ancestors. a few tick species were recently found to harbor maternally-inherited coxiella-like organisms engaged in symbiotic interactions, but their relationships to the q fever ... | 2015 | 25978383 |
| identification of tick species and disseminate pathogen using hemolymph by maldi-tof ms. | matrix assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tof ms) is increasingly emerging tool for identification of arthropods including tick vectors using whole or body part of specimens. the challenges of the present study were to assess maldi-tof ms profiling for the both identification of tick species and rickettsia spp. in infected ticks using hemolymph as protein mixture. | 2015 | 26051210 |
| [distribution of tick species spread in kütahya vicinity]. | this study was performed to determine the tick species infested to the cattle and small ruminants in kütahya province and their seasonal activity and prevalence. | 2015 | 26081885 |
| anaplasma infection in ticks, livestock and human in ghaemshahr, mazandaran province, iran. | anaplasmosis is an important issue for animal breeders in terms of economic losses as well as a health concern to human. ticks are considered as the main vector of this disease. lack of documented information about anaplasma species in iran was the scope of this study to determine the population of ticks and the presence of anaplasma in ticks, domestic ruminants and also human beings in northern iran. | 2014 | 26114134 |
| transmission of babesia ovis by different rhipicephalus bursa developmental stages and infected blood injection. | in this report, the transmission efficacy of babesia ovis, the principal causative agent of ovine babesiosis, was studied by infestation of lambs with different rhipicephalus bursa stages or by injection of infected blood. infected blood injection induced acute babesiosis in splenectomized lambs, while only mild clinical signs were observed in intact animals. both splenectomized and intact lambs developed high antibody titer, detectable for at least 180 days post infection. infestation of splene ... | 2016 | 26253782 |