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[new findings on the ecology and epidemiology of murine herpes virus isolated in slovakia].rodents are important reservoir animals of many human microbial pathogens. of small rodents, trapped on slovakia territory, were several strains of murine herpes virus (mhv) isolated. our purpose was to complete the existing knowledge about circulation of mhv in rodents and to find out, whether also other animal species including man are mhv sensitive or not. the presence of antibodies against mhv in serum of the tested animals and men was followed by virus neutralization test (vnt) and elisa. p ...200010870260
prevalence of igg antibodies response to borrelia burgdorferi s.l. in populations of wild rodents from mazury lakes district region of poland.three rodent species: clethrionomys glareolus, apodemus flavicollis and microtus arvalis from mazury lakes district of poland were examined for antibodies to borrelia burgdorferi by enzyme-labelled protein g assay (elga). c. glareolus had an exceptionally high prevalence of b. burgdorferi antibodies - 58%, but a. flavicollis and m. arvalis also showed significant prevalence of 16.6% and 10.5%, respectively. the elga method is highly specific with good reproducibility. nevertheless, some differen ...200011153035
dobrava hantavirus causes hemorrhagic fever with renal syndrome in central europe and is carried by two different apodemus mice species.in central europe, hemorrhagic fevers with renal syndrome (hfrs) in humans are caused by the hantavirus species puumala (transmitted by voles) and a second, hantaan-related species (transmitted by mice). the second virus could be identified as dobrava virus. to date, 19 clinical cases of dobrava infection have been found in germany and slovakia. all patients exhibited a mild/moderate clinical course and no case fatality occurred. screening for infected rodents revealed that the striped field mou ...200111170053
findings of mycobacteria in insectivores and small rodents.the organs of 30 insectivorous mammals and 62 rodents from areas inhabited by people or livestock where cattle paratuberculosis or mycobacterial infections of swine had been found to occur were examined by cultivation during the monitoring of occurrence and spread of mycobacterioses in cattle and swine. mycobacteria were found in the organs of 3 insectivores (10%) and 6 rodents (9.7%). mycobacterium chelonae was isolated from the organs of the lesser white-toothed shrew (crocidura suaveolens) an ...200011271823
analysis of a novel strain of murine gammaherpesvirus reveals a genomic locus important for acute pathogenesis.infection of mice by murine gammaherpesvirus 68 (mhv-68) is an excellent small-animal model of gammaherpesvirus pathogenesis in a natural host. we have carried out comparative studies of another herpesvirus, murine herpesvirus 76 (mhv-76), which was isolated at the same time as mhv-68 but from a different murid host, the yellow-necked mouse (apodemus flavicollis). molecular analyses revealed that the mhv-76 genome is essentially identical to that of mhv-68, except for deletion of 9,538 bp at the ...200111333912
isolation of dobrava virus from apodemus flavicollis in greece.dobrava virus (dobv) carried by apodemus flavicollis is the causative agent of severe hemorrhagic fever with renal syndrome (hfrs). dobv was isolated from an a. flavicollis mouse trapped in northeastern greece. this is the third dobv cell culture isolate in the world, clustering together with other greek dobv sequences from hfrs patients and rodents.200111376073
morphological and genetic differentiation of rodentolepis straminea (goeze, 1752) and rodentolepis microstoma (dujardin, 1845) (hymenolepididae).the two related species, rodentolepis straminea (goeze, 1782) and rodentolepis microstoma (dujardin, 1845) (cestoda, hymenolepididae), both parasites of rodents, were compared morphologically and electrophoretically. adult worms were isolated from three wild rodent species of the family muridae (apodemus flavicollis, apodemus sylvaticus, and mus musculus) from three different sites in spain and france. although these two species were strikingly similar in morphological appearance, some of the mo ...200111411941
importance of surveillance of tularemia natural foci in the known endemic area of central europe, 1991-1997.marked activation of natural foci of tularemia in the known endemic area of central europe, comprising the borderland of slovakia, austria and the czech republic, led to an epidemic outbreak in western slovakia and an increase in the number of human tularemia cases in the adjoining regions of northeastern austria and southern moravia from 1995 to 1997. the aim of this paper was to present the results of a longitudinal study on the prevalence of infection with francisella tularensis in small mamm ...200111467089
hantavirus infections in greece--an update.hantaviruses are emerging viruses spread worldwide and cause hemorrhagic fever with renal syndrome (hfrs) or hantavirus pulmonary syndrome (hps). two pathogenic hantaviruses are present in greece: dobrava/belgrade virus (dobv) and puumala virus (puuv). the predominant one is dobv, carried in greece by the rodent apodemus flavicollis. most human infections are sporadic, but epidemic outbreaks were also described. the severity of the disease ranges from a mild or moderate form to severe and fatal ...200111599695
antigenic profile of ixodes ricinus: effect of developmental stage, feeding time and the response of different host species.antigens recognized by host species in response to ectoparasite infestation have been widely reported. although differences in the immune responses of different host species have been described, only a very few of these studies compare the range of antigens recognized by different host species in response to infestation. we used western blot analysis to investigate antigenic responses of different host species that were repeatedly infested with ixodes ricinus ticks. antigenic profiles of larval ...200111696166
prevalence and abundance of cryptosporidium parvum and giardia spp. in wild rural rodents from the mazury lake district region of poland.prevalence and abundance of cryptosporodium parvum and giardia spp. were studied in 3 species of rodents from forests and abandoned agricultural fields in n.e. poland (clethrionomys glareolus n = 459; microtus arvalis n = 274; apodemus flavicollis n = 209). overall prevalence was consistently higher in the voles compared with a. flavicollis (70.6, 73.0 and 27.8% respectively for c. parvum and 93.9, 96.3 and 48.3% respectively for giardia spp.). prevalence and abundance of infection also varied m ...200212166517
rodent host specificity of european hantaviruses: evidence of puumala virus interspecific spillover.in order to investigate rodent host specificity of european hantaviruses, experimental infection of colonized and wild-trapped rodents was performed. in addition to the natural rodent reservoir, clethrionomys glareolus, puumala hantavirus (puuv) could infect colonized microtus agrestis and lemmus sibiricus, but not syrian hamsters or balb/c mice. neither c. glareolus, nor m. agrestis, could be readily infected by tula hantavirus (tulv). wild-trapped apodemus flavicollis and a. agrarius, the natu ...200212376967
epidemiologic characteristics and military implications of hemorrhagic fever with renal syndrome in croatia.to analyze epidemiologic characteristics of hemorrhagic fever with renal syndrome in croatia, including military implications of the disease and measures for its prevention.200212402401
genetic interaction between distinct dobrava hantavirus subtypes in apodemus agrarius and a. flavicollis in nature.dobrava virus (dobv) occurs in two different rodent species, apodemus flavicollis (dobv-af) and a. agrarius (dobv-aa). we sequenced the s and m genomic segments from sympatric dobv-af and dobv-aa strains which fell into two distinct genetic lineages. molecular phylogenetic analyses gave evidence for genetic reassortment between s and m segments of dobv-af and dobv-aa and indicated homologous recombination events in dobv evolution. dobv-af and dobv-aa are distinct but also subject to genetic exch ...200312477889
genetic characterization of new dobrava hantavirus isolate from greece.the first complete genome sequence of dobrava hantavirus isolated from yellow-necked mouse apodemus flavicollis trapped in the northeastern greece is described. the s, m, and l segments of the greek isolate of dobrava virus are 1673, 3635, and 6532 nucleotides (nt) long, respectively, and encode the nucleocapsid (n) protein of 429 amino acids (aa), glycoprotein precursor of 1135 aa, and the l protein of 2151 aa. n protein contains three cysteine residues conserved in all known hantaviruses, as w ...200312526053
a comparative analysis of the heavy metal loading of small mammals in different regions of bulgaria i: monitoring points and bioaccumulation features.data on liver and body copper, zinc, lead, and cadmium content of small mammals (rodents and insectivorous) were collected and analyzed. data comparisons were performed in two aspects: (1) points and years of monitoring; (2) monitor species bioaccumulations. specific bioaccumulation features were observed in some of the monitor species. a method for comparative evaluation of heavy metal loads in the different species is proposed using data for liver and body contamination. the loads of clethrion ...200312550095
a comparative analysis of the heavy metal loading of small mammals in different regions of bulgaria ii: chromosomal aberrations and blood pathology.heavy metal content was monitored in small mammals inhabiting mountain ecosystems and two industrial polluted regions in bulgaria. rodents (microtus arvalis, m. rossiaemeridionalis, clethrionomys glareolus, pitymys subterraneus, chionomys nivalis, apodemus flavicollis, a. sylvaticus, and mus macedonicus) were used as zoomonitors. pathological changes in chromosome status, hematological indices, and blood cell morphology were analyzed in the context of heavy metal bioaccumulation. significant cor ...200312550096
bartonella infection in sylvatic small mammals of central sweden.sylvatic small mammals were captured in rural habitats near uppsala, sweden, to measure the prevalence of bartonella infections, characterize bacterial isolates and identify their host range, and increase our understanding of host-pathogen ecology. during 7 nights of trapping at 3 localities, 236 small mammals were captured (trap success 30%). bartonella were isolated from bloods of apodemus flavicollis (19 of 110 tested), apodemus sylvaticus (6/25), clethrionomys glareolus (9/60), microtus agre ...200312613756
the molecular evidence of babesia microti infection in small mammals collected in slovenia.in europe, the zoonotic cycle of babesia microti has not been determined so far. recently, b. microti was detected in ixodes ricinus ticks in slovenia by using molecular methods. in order to investigate the mammalian hosts of b. microti in slovenia we collected 261 small mammals representing 11 species. they were tested for the presence of babesial parasites with a pcr assay based on the nuclear small subunit rrna gene (nss-rdna). the bank vole (clethrionomys glareolus) and yellow-necked mouse ( ...200312636348
empirical evidence for key hosts in persistence of a tick-borne disease.an important epidemiological consequence of aggregated host-parasite associations occurs when parasites are vectors of pathogens. those hosts that attract many vectors will tend to be the focus of transmission. but to what extent, and can we identify characteristics of these key hosts? we investigated these questions with respect to the host-tick relationship of the yellow-necked mouse, apodemus flavicollis, a critical host in the maintenance of the zoonotic disease, tick-borne encephalitis. tra ...200312906875
natural foci of the western type of north american equine encephalomyelitis (wee) in czechoslovakia. v. isolation of the wee virus from the brain of apodemus flavicollis. 195713545060
experimental infection of clethrionomys glareolus and apodemus flavicollis with tick-borne encephalitis virus. 196314062331
hantavirus infections in europe.hantaviruses are enveloped rna viruses each carried by a specific rodent species. three hantaviruses, puumala, dobrava, and saaremaa viruses, are known to cause haemorrhagic fever with renal syndrome. in europe. puumala causes a generally mild disease, nephropathia epidemica, which presents most commonly with fever, headache, gastrointestinal symptoms, impaired renal function, and blurred vision, whereas dobrava infections often also have haemorrhagic complications. there are few available data ...200314522264
preliminary molecular characterization of cryptosporidium parvum isolates of wildlife rodents from poland.isolates of cryptosporidium were collected from 3 species of woodland and field rodents (clethrionomys glareolus, microtus arvalis, and apodemus flavicollis) and were characterized by polymerase chain reaction amplification and sequencing of fragments of the oocyst wall protein (cowp) gene and of the 18s ribosomal rna gene. sequence analysis of these markers revealed that the animals were infected with c. parvum, and that the genotype involved was almost identical to the mouse genotype previousl ...200314627156
biological characterisation of cryptosporidium parvum isolates of wildlife rodents in poland.the study was undertaken to characterise the c. parvum isolates originating from naturally infected woodland and field rodents: clethrionomys glareolus (cg), apodemus flavicollis (af) and microtus arvalis (ma). we found that the measurements of oocyst dimensions and oocyst morphology did not allow distinction between the parasite isolates from the 3 rodent species. the mean dimensions were: for cg 4.67 x 4.21, for af 4.65 x 4.14 and for ma 4.66 x 4.16. these 3 groups of isolates have produced si ...200314677907
two-year study of examination of blood from wild rodents for the presence of antiborrelian antibodies.the aim of our work was to find the positivity rate of antibodrrelian antibodies (igg) in wild-living rodents in a locality situated in north moravia, czech republic. results of a survey for heart rinses (172) and sera (2) antibodies to borrelia burgdorferi sensu lato (s.l.) from 6 species of 174 wild rodents from the northern part of the czech republic are presented. samples were obtained in 2001-2002 at one locality (studenka, 49 degrees 44', 18 degrees 05'). host samples included yellow-necke ...200314677912
high levels of fluctuating asymmetry in populations of apodemus flavicollis from the most contaminated areas in chornobyl.random deviations from the perfect symmetry of normally bilaterally symmetrical characters for an individual with a given genotype occur during individual development due to the influence of multiple environmental factors. fluctuating asymmetry (fa) is often used as a measure of developmental instability, and can be estimated as the variance of the distribution of differences between the left and right sides. we addressed the question of whether levels of fa were elevated in radioactively contam ...200415001292
immunoglobulin g antibodies to borrelia burgdorferi in game animals and small mammals in eastern slovakia.in a survey of game animals and small mammals, the sera of 185 animals were examined for the presence of immunoglobulin g antibodies to the spirochete borrelia burgdorferi sensu lato, which causes lyme borreliosis. these animals comprised 59 fallow deer (dama dama), 56 mouflons (ovis musimon) and 70 small mammals of six different species. the sera of the fallow deer and the mouflons were examined by indirect haemagglutination assay. the sera of the small mammals were examined by modified enzyme- ...200315005560
[puumala and dobrava viruses in the northeastern and central regions of bosnia].bosnia and herzegovina has been known as a highly endemic region for hantavirus infections for more than 50 years. previous studies have shown that at least two different hantaviruses, the murine dobrava (dob) and avricoline puumala (puu) viruses, each carried by a different rodent species, have been circulating in the area. however, there is little information on rodent population density fluctuations in bosnia over the past years as well as on the ratio of puumala to dobrava infection in human ...200315011464
[what is new in the epidemiologic characteristics of hemorrhagic fever with renal syndrome in croatia?].the aim was to describe epidemiologic characteristics of hemorrhagic fever with renal syndrome in croatia.200315011468
yeast-expressed hantavirus dobrava nucleocapsid protein induces a strong, long-lasting, and highly cross-reactive immune response in mice.in europe, dobrava virus (dobv) carried by the yellow-necked field mouse apodemus flavicollis is one of the hantaviruses that can cause severe hemorrhagic fever with renal syndrome in humans. for several hantaviruses, the nucleocapsid (n) protein has proven to be very immunogenic in humans and rodents and even can protect rodents against a virus challenge. to investigate the immunogenicity of dobv n protein, balb/c and c57bl/6 mice were immunized three times with a dobv recombinant n (rn) protei ...200415018668
b chromosomes and developmental homeostasis in the yellow-necked mouse, apodemus flavicollis (rodentia, mammalia): effects on nonmetric traits.b chromosomes are found in almost all populations of the yellow-necked mouse, apodemus flavicollis (rodentia, mammalia). their effects on developmental homeostasis in this species were analyzed using morphological nonmetric traits (number of foramina) in a sample of 218 animals from locality mt jastrebac in the former yugoslavia. variations of the parameters of developmental homeostasis (the degree of fluctuating asymmetry--fa, the number of asymmetrical characters per individual--na, and the to ...200415100709
the zoonotic reservoir of borrelia burgdorferisensu lato in the mazury lakes district of north-eastern poland.the roles of two species of rodents: the bank vole (clethrionomys glareolus) and the yellow-necked mouse (apodemus flavicollis) in maintaining the vector ixodes ricinus and borrelia burgdorferi s.l. were studied. more particularly, seasonal patterns of rodent abundance and infestation rate with i. ricinus ticks as well as the prevalence of b. burgdorferi s.l. and the two species b. garinii and b. afzelii were determined. the studies were carried out in woodlands at urwitałt near mikołajki on the ...200415147002
phylogeographic history of the yellow-necked fieldmouse (apodemus flavicollis) in europe and in the near and middle east.the exact location of glacial refugia and the patterns of postglacial range expansion of european mammals are not yet completely elucidated. therefore, further detailed studies covering a large part of the western palearctic region are still needed. in this order, we sequenced 972 bp of the mitochondrial dna cytochrome b (mtdna cyt b) from 124 yellow-necked fieldmice (apodemus flavicollis) collected from 53 european localities. the aims of the study were to answer the following questions: did th ...200415288056
so close and so different: comparative phylogeography of two small mammal species, the yellow-necked fieldmouse (apodemus flavicollis) and the woodmouse (apodemus sylvaticus) in the western palearctic region.in europe, concordant geographical distribution among genetic lineages within different species is rare, which suggests distinct reactions to quaternary ice ages. this study aims to determine whether such a discrepancy also affects a pair of sympatric species, which are morphologically and taxonomically closely related but which have slight differences in their ecological habits. the phylogeographic structures of two european rodents, the yellow-necked fieldmouse (a. flavicollis) and the woodmou ...200515329664
evolution of mhc-drb class ii polymorphism in the genus apodemus and a comparison of drb sequences within the family muridae (mammalia: rodentia).allelic diversity at major histocompatibility complex (mhc) genes is thought to be maintained by balancing selection over long periods of time, even across multiple speciation events. trans-species sharing of mhc alleles among genera has been supported by many studies on mammals and fish, but in rodents, the results are ambiguous. we investigated natural levels of mhc- drb variability and evolutionary processes in the wood mouse (apodemus sylvaticus) and the yellow-necked mouse (apodemus flavico ...200415351919
identification of bartonella species in rodents, shrews and cats in denmark: detection of two b. henselae variants, one in cats and the other in the long-tailed field mouse.small mammals and stray cats were trapped in two areas of north zealand, denmark, and their blood cultured for hemotrophic bacteria. bacterial isolates were recovered in pure culture and subjected to 16s rdna gene sequencing. bartonella species were isolated from five mammalian species: b. grahamii from microtus agrestis (field vole) and apodemus flavicollis (yellow-necked field mouse); b. taylorii from m. agrestis, a. flavicollis and a. sylvaticus (long-tailed field mouse); b. tribocorum from a ...200415511270
granule cell number, cell death and cell proliferation in the dentate gyrus of wild-living rodents.adult neurogenesis in the dentate gyrus occurs at species-specific levels. wood mice (apodemus flavicollis) show higher proliferation rates than laboratory mice and voles (clethrionomys glareolus, microtus subterraneus). we compare rates of cell death and proliferation and investigate if cell proliferation leads to the long-term recruitment of granule cells. granule and pyknotic cell numbers were estimated in wild-living rodents in different age classes and compared with laboratory mice of mixed ...200415610166
differential gene expression in yellow-necked mice apodemus flavicollis (rodentia, mammalia) with and without b chromosomes.most b chromosomes are heavily heterochromatic, promoting the general idea that they are genetically inert. the b chromosomes of apodemus flavicollis are euchromatic and show a high degree of homology with the a chromosomes. the euchromatic nature of b chromosomes in a. flavicollis suggests that they may carry active genes and have transcriptional activity. we applied the differential display reverse transcription-polymerase chain reaction (dd rt-pcr) in order to analyze and compare gene express ...200515657744
identification of genetic evidence for dobrava virus spillover in rodents by nested reverse transcription (rt)-pcr and taqman rt-pcr.a survey of 158 rodents caught in the czech republic identified dobrava virus sequences closely related to that of the dobrava virus type strain in apodemus sylvaticus and mus musculus rodents. the identity of a. sylvaticus was unequivocally confirmed by random amplified polymorphic dna analysis. the data seem to indicate hantavirus spillover from apodemus flavicollis to other rodents.200515695684
distribution of cadmium and lead in liver and kidney of some wild animals in slovakia.the content of cadmium and lead, as risk factors of environment, in liver and kidneys of wild animals as brown hare (lepus europaeus), yellow-necked mouse (apodemus flavicollis), wood mouse (cleithrionomys glareolus), and red deer (cervus elaphus) were studied. samples were analyzed by the atomic absorption spectrophotometry method (aas). the highest levels of cadmium were found in kidneys (0.213-2.387 mg/kg) of all animal species. the concentration of cadmium in liver was 0.032-0.258 mg/kg. the ...200515756970
seroepidemiology of borrelia burgdorferi sensu lato and anaplasma phagocytophilum in wild mice captured in northern turkey.an expedition across the asian part of the black sea coast and national parks of northern turkey was organized in the summer of 2001 to investigate the presence of borrelia burgdorferi sensu lato (s.l.), lyme borreliosis agent, and anaplasma phagocytophilum, human granulocytic ehrlichiosis, agent, in wild mice. a total of 65 apodemus flavicollis, apodemus sylvaticus, microtus epiroticus, crocidura suaveolens and mus macedonicus, were captured. two out of 22 apodemus sylvaticus specimens were ser ...200515816159
mhc diversity and the association to nematode parasitism in the yellow-necked mouse (apodemus flavicollis).in vertebrates, the genes of the major histocompatibility complex (mhc) are among the most debated candidates accounting for co-evolutionary processes of host-parasite interaction at the molecular level. the exceptionally high allelic polymorphism found in mhc loci is believed to be maintained by pathogen-driven selection, mediated either through heterozygous advantage or rare allele advantage (= frequency dependent selection). while investigations under natural conditions are still very rare, s ...200515910340
cluster of capillaria hepatica infections in non-commensal rodents from the canton of geneva, switzerland.we trapped 664 rodents belonging to five non-commensal species in the canton of geneva, switzerland, and found a significant cluster of capillaria hepatica infections in three species in rural and urbanized areas of the northern part of the canton. c. hepatica infections were discovered in the yellow-necked mouse apodemus flavicollis (n=99) with an overall prevalence (op) of 7.0% and a clustered prevalence (cp) of 20%, in the bank vole clethrionomys glareolus (n=58, op 5.2%; cp 19%), and in the ...200515924224
central european dobrava hantavirus isolate from a striped field mouse (apodemus agrarius).dobrava virus (dobv) is a hantavirus that causes hemorrhagic fever with renal syndrome (hfrs) in europe. it is hosted by at least two rodent species, apodemus flavicollis and a. agrarius. according to their natural hosts they form the distinct genetic lineages dobv-af and dobv-aa, respectively. we have now established a dobv isolate named slovakia (sk/aa) from an a. agrarius animal captured in slovakia. the complete s and m and partial l segment nucleotide sequences of the new isolate were deter ...200515956394
[mycobacterium avium subsp. paratuberculosis in wild animal species and cattle in styria/austria].infections with mycobacterium ovium ssp. paratuberculosis (m. paratuberculosis) are increasingly recognised worldwide. in addition to an increased prevalence of paratuberculosis in austrian cattle herds, recent years have also shown a rise in infections with m. paratuberculosis in wild red and roe deer, chamois and mouflon. during the period from june 2002 to september 2004, mesenteric lymph nodes were taken from a total of 483 wild animals hunted or found dead and from 338 deceased cattle. samp ...200516048043
intra individual variation in the number of b chromosomes in the yellow-necked mouse, apodemus flavicollis (mammalia, rodentia).the yellow-necked mouse, apodemus flavicollis, is characterized by a frequent occurrence of b chromosomes. the frequency of intra individual mosaicism of bs was studied in 995 animals collected at six localities in serbia. it was found that 329 (33.06%) possessed b chromosomes. among these, 87 animals (26.44%) were mosaics. a total of 32 mosaic animals with more than one b chromosome were analyzed for distribution of bs which was found to be quite different between groups of animals with differe ...200516212112
borrelia burgdorferi sensu stricto in yellow-necked mice and feeding ixodes ricinus ticks in a forest habitat of west central poland.wild rodents and the subadult ixodes ricinus (l.) ticks infesting them were examined for the presence of borrelia burgdorferi johnson, schmid, hyde, steigerwalt & brenner s.l. in a sylvatic habitat in west central poland during may-september 2002. in total, 818 feeding ticks were recovered from 73 infested yellow-necked mice, apodemus flavicollis melchior; in addition, bank voles, clethrionomys glareolus schreber, were rarely captured and proved to be weakly parasitized. only 2.7% of a. flavicol ...200516363171
hantavirus and arenavirus antibody prevalence in rodents and humans in trentino, northern italy.the spatial and temporal distribution of hantavirus and arenavirus antibody-positive wild rodents in trentino, italy, was studied using immunofluorescence assays (ifa) in two long-term sites trapped in 2000-2003, and six other sites trapped in 2002. the overall hantavirus seroprevalence in the bank voles, clethrionomys glareolus (n=229) screened for puumala virus (puuv) antibodies was 0.4%, and that for apodemus flavicollis mice (n=1416) screened for dobrava virus (dobv) antibodies was 0.2%. ant ...200616371172
babesia microti: prevalence in wild rodents and ixodes ricinus ticks from the mazury lakes district of north-eastern poland.infections of babesia microti (apicomplexa, piroplasmida), a common erythroparasitic protozoon of holarctic rodents, are not widely acknowledged in poland. the presence of this parasite in various species of wild rodents has been well documented throughout the northern temperate zone of north america, europe, and eurasia. however, human babesiosis attributable to infection with b. microti has been reported only from the north-eastern and upper midwestern united states and japan. we recently carr ...200616524774
is there an association of pneumocystis infection with the presence of arena-, hanta-, and poxvirus antibodies in wild mice and shrews in finland?as part of studies on the nature of the endemic virus infections in natural rodent hosts, the possible association of cyst forms of pneumocystis spp. with the presence of hanta-, cowpox-, and arenavirus antibodies in wild mice (apodemus flavicollis, n=105; apodemus agrarius, n=63; micromys minutus, n=50) and the common shrew (sorex araneus, n=101) was studied in south-central finland. one hantavirus (saaremaa virus, saav) seropositive a. agrarius, and 2 cowpoxvirus (cpxv) seropositive s. araneus ...200616556344
murine gammaherpesvirus (mhv) mk3 gene sequence diversity among 72, 4556, and 68 strains.murid herpesvirus 4 (muhv-4) currently serves as a model for study of human gamma-herpesvirus pathogenesis. it codes for mk3 protein that similarly as k5 protein of kaposi's sarcoma-associated herpesvirus are members of a family of structurally related viral immune evasion molecules possessing ring-ch finger domain with ubiquitin ligase activity. murine herpesvirus 72 (mhv-72) isolated from the same species of free-living small rodent is considered as closely related to murine herpesvirus 68 (mh ...200616791419
[prevalence of ixodes ricinus infection with borrelia burgdorferi s.l.: seasonal and annual variations].the present study deals with the ecology of lyme borreliosis in northern poland. the complexity of environmental conditions are: (1) the presence of certain rodent hosts for the borrelia, (2) the seasonal patterns of abundance and infection rate of i. ricinus in the population of rodents and on vegetation, (3) the prevalence of b. burgdorferi s.l., b. garinii and b. afzelii. the long-term studies were carried out on a monthly basis from april to october (1998-2001) in woodlands at urwitałt near ...200416859032
[the co-occurence of cryptosporidium parvum, giardia spp. and helminth infections in small rodent populations].during long-term (1998-2000) studies on rodent parasite populations in mazury lake district there were collected and analyzed data on co-occurrence of intestinal protozoa (cryptosporidium parvum, giardia spp.) and helminths. there were performed 178 autopsies of common vole microtus arvalis, 85 autopsies of yellow-necked mouse apodemus flavicollis and 386 autopsies of bank vole clethrionomys glareolus. positive effect of helminth infections was found in c. glareolus. voles infected with nematode ...200416859041
[anoplura of rodents (rodentia) in northern poland].anoplura of rodents (rodentia) in northern poland. above 100 rodents belonging to 6 species (clethrionomys glareolus, microtus agrestis, m. arvalis, apodemus flavicollis, a. sylvaticus, mus musculus) caught in the various habitations were examined. the parasites found represented three species of anoplura: hoplopleura acanthopus, h. affinis and polyplax serrata. h. acanthopus appeard to be the most common parasite; it was found in all examined hosts, while mostly on the bank vole.200416859044
[co-infection of borrelia garinii and b. afzelii in a population of wild rodents from woodland].the maintenance of borrelia burgdorferi s.l. in the environment is dependent on the zoonotic cycle involving tick vectors and certain reservoir hosts. it is well known, that the same species of wild rodents, as well as the vector ixodes ricinus, are often co-infected with at least two genomospecies of b. burgdorferi s.l.: b. afzelii and b. garinii. the ticks collected from two rodent species: clethrionomys glareolus and apodemus flavicollis were examined for the presence of b. burgdorferi s.l., ...200116886420
[the ecology of cryptosporidium parvum infection in small rodent populations].the prevalence and abundance of cryptosporidium parvum were studied over a three year period (1997-1999) in three species of rodents sampled from forest and abandoned fields in the mazury lake district, poland. the overall prevalence was consistently higher in voles compared with apodemus flavicollis (70.6% in clethrionomys glareolus, 73.0% in microtus arvalis and 27.8% in a. flavicollis). the prevalence and abundance of infection also varied across the 3 years of the study with 1998 being the y ...200116886421
simple epidemiological model predicts the relationships between prevalence and abundance in ixodid ticks.we tested whether the prevalence of ticks can be predicted reliably from a simple epidemiological model that takes into account only mean abundance and its variance. we used data on the abundance and distribution of larvae and nymphs of 2 ixodid ticks parasitic on small mammals (apodemus agrarius, apodemus flavicollis, apodemus uralensis, clethrionomys glareolus and microtus arvalis) in central europe. ixodes trianguliceps is active all year round, occurs in the study area in the mountain and su ...200717032480
selection in a cycling population: differential response among skeletal traits.population density cycles influence phenotypic evolution through both density-dependent selection during periods of high density and through enhanced genetic drift during periods of low density. we investigated the response of different phenotypic traits to the same density cycles in a population of the yellow-necked mouse, apodemus flavicollis, from białowieza national park in poland. we examined nonmetric skull traits, skull and mandible size, skull and mandible shape, and transferrin allele f ...200617089976
[wild small mammals are the reservoir hosts of the bartonella genus bacteria in the south of moscow region].a total of 103 blood samples collected from wild small mammals captured in the prioksko-terrasny reserve on the south of moscow region were studied to determine the bartonellae prevalence. the examined species were the yellow-necked mice apodemus flavicollis (35 samples), the european wood mouse apodemus uralensis (10 samples), the bank vole clethrionomys glareolus (51 samples), the house mouse mus musculus (3 samples), the common vole microtus arvalis (2 samples), and the shrew sorex araneus (2 ...200617094651
parasites of two abundant sympatric rodent species in relation to host phylogeny and ecology.in the present study, two abundant sympatric rodent species (27 apodemus flavicollis and 33 a. sylvaticus) were studied for their endo- and ectoparasite fauna. the rodents were trapped in dormagen, a city in north rhine-westphalia, germany. a total of 20 different parasites species were identified, 13 endoparasite (2 digenea, 5 cestoda and 7 nematoda) and 7 ectoparasite (5 insecta and 2 arachnida) species. thirteen parasite species were found inhabiting both rodent species. the predominant endop ...200717120043
[helminth fauna of rodents (arvicolidae and muridae) from the kampinos national park].the aim of the study was to examine the parasite fauna of rodents living in natural environment, but in close contact with human seats (small village at the area of the natural big forest).200617120995
seasonal variations in detecting borrelia burgdorferi sensu lato in rodents from north eastern austria.austria is well known as an endemic area of lyme borreliosis. to assess the annual variation of rodent populations that may host agents of lyme borreliosis we collected rodents in northeastern austria. life traps were set out every six weeks during a year consecutively in one each of the three different zones (hohenau, ernstbrunn, vienna woods) that cover the main habitat characteristics of small mammals in northeastern austria. rodents were collected and identified. samples of heart, urine blad ...200617186171
the role of sex in parasite dynamics: model simulations on transmission of heligmosomoides polygyrus in populations of yellow-necked mice, apodemus flavicollis.we investigated possible mechanisms that could cause sex-biased parasite transmission of the helminth heligmosomoides polygyrus in its rodent host, apodemus flavicollis, using a modelling approach. two, not mutually exclusive, hypotheses were examined: that sex-biased parasite transmission is caused by differences in immunity that influence the success of free-living stages and/or is caused by sex differences in host behaviour and the dissemination of infective stages. model simulations were com ...200717188276
abundance of wild rodents, ticks and environmental risk of lyme borreliosis: a longitudinal study in an area of mazury lakes district of poland.the results of a longitudinal epidemiological survey in two contrasting habitats in an area of the mazury lakes district of poland indicate that both host and vector (ixodes ricinus) densities, may be the most important risk factors for the tick-transmitted spirochetes of borrelia burgdirferi s.l. however, the results also highlight that even related host species, such as the wild rodents apodemus flavicollis and clethrionomys glareolus that share the same habitat, can show quite different dynam ...200617196004
molecular detection of bartonella species infecting rodents in slovenia.rodents, collected in three zoogeographical regions across slovenia, were tested for the presence of bartonellae using direct pcr-based amplification of 16s/23s rrna gene intergenic spacer region (its) fragments from splenic dna extracts. bartonella dna was detected in four species of rodents, apodemus flavicollis, apodemus sylvaticus, apodemus agrarius and clethrionomys glareolus, in all three zoogeographic regions at an overall prevalence of 40.4%. the prevalence of infection varied significan ...200717374132
detection of ehrlichia muris in a yellow-necked mouse (apodemus flavicollis) in central slovakia. 200717432949
detection of dobrava hantaviruses in apodemus agrarius mice in the transdanubian region of hungary.dobrava hantavirus (dobv) belongs to the genus hantavirus of the family bunyaviridae, and is carried by yellow necked and striped field mice (apodemus flavicollis and apodemus agrarius), respectively. the aim of this study was to detect and genetically characterize new dobv strains in rodents captured in the transdanubian region of hungary. rodent corpses were dissected and lung tissues were used for hantavirus detection by sybr green-based real-time rt-pcr using specific primers located in the ...200717524512
an attempt to control a natural focus of leptospirosis grippotyphosa by rodenticide--a long-term study (1977-2004).the purpose of the study was to suppress a known natural focus of field fever exerting an influence on animal hosts of leptospires--small terrestrial mammals (s.t.m.) by rodenticide. after repeated application of the zinc phosphide rodenticide, the s.t.m. were regularly live-trapped and checked for leptospirosis by dark-field microscopy and culture of their renal tissue and serological examination. isolated leptospira strains were typed by help of rabbit factor sera. the deratization influenced ...200717655177
tick-borne zoonotic bacteria in wild and domestic small mammals in northern spain.the prevalence and diversity of tick-borne zoonotic bacteria (borrelia spp., anaplasma phagocytophilum, coxiella burnetii, and spotted fever group rickettsiae) infecting 253 small mammals captured in the basque country (spain) were assessed using pcr and reverse line blot hybridization. trapping sites were selected around sheep farms (study 1, 2000 to 2002) and recreational parks (study 2, 2003 to 2005). the majority of the studied mammals (162) were wood mice (apodemus sylvaticus), but six othe ...200717693556
temporal variation of ixodes ricinus intensity on the rodent host apodemus flavicollis in relation to local climate and host dynamics.the risk to humans of contracting tick-borne zoonotic diseases depends on the risk of a bite from an infected tick, which can be broken down into its component parts as the number of host-seeking ticks in the environment, in particular nymphs, and the prevalence of tick-borne pathogens they are carrying. in turn, the prevalence of tick-borne pathogens is dependent upon tick biting intensity on hosts that support transmission between ticks; namely rodents. these ticks once fed moult into the next ...200717760511
[sex chromosomes at early meiosis in three wood mice species of the genus apodemus (rodentia, muridae)].the prophase of the first meiotic division was studied in field mice of the species apodemus (sylvaemus) flavicollis, a. (s.) ponticus, and a. (s.) uralensis by light and electron microscopy. the karyotypes of the species were described on the base of electron microscopy of synaptonemal complexes in spermatocytes i. the axial elements of the sex chromosomes at early-middle pachytene can synapse along the major portion of the y axis; at late pachytene-early diplotene, the synapsis region shrinks; ...200717853806
host specificity and genealogy of the louse polyplax serrata on field mice, apodemus species: a case of parasite duplication or colonisation?the genealogy, population structure and population dynamics of the sucking louse polyplax serrata were analysed across four host species of the genus apodemus. an analysis of 126 sequences of cytochrome c oxidase subunit i using phylogenetic approaches and haplotype networking revealed a clear structure of european samples, forming three distinct and genetically distant clades with different host specificities. although a clear connection was detected between the host and parasite genealogies/ph ...200818021782
[the impact of nematode invasions on the pattern of cryptosporidium parvum infection in wild rodents].fragmentation of the environment by natural barriers (lakes, mountain ranges) and human activities (towns, major roads, agriculture) can lead to isolated subpopulations of hosts. the study was carried out in mazury lake district in north-east of poland, the region rich in forests, lakes, rivers and canals, which are able to create passable such barriers. population of bank voles (myodes glareolus) and yellow-necked mice (apodemus flavicollis)--dominant woodland rodents--showed local differences ...200718075159
bartonella spp. infection in rodents from different habitats in the mazury lake district, northeast poland.four rodent species (clethrionomys glareolus, apodemus flavicollis, microtus arvalis, m. oeconomus) were captured in the period 2004-2006 in the mazury lake district, northeast poland, to determine the prevalence and genetic diversity of bartonella species. the presence of bartonellae was assessed using polymerase chain reaction (pcr) with primers cs140f and bhcs1137n, amplifying a fragment of the glta gene. bartonella dna was detected in 313 (30.6%) of 1024 rodents sampled: in 181 c. glareolus, ...200818399782
estimating the exposure of small mammals at three sites within the chernobyl exclusion zone--a test application of the erica tool.an essential step in the development of any modelling tool is the validation of its predictions. this paper describes a study conducted within the chernobyl exclusion zone to acquire data to conduct an independent test of the predictions of the erica tool which is designed for use in assessments of radiological risk to the environment. small mammals were repeatedly trapped at three woodland sites between early july and mid-august 2005. thermoluminescent dosimeters mounted on collars were fitted ...200818450342
the effects of social structure and sex-biased transmission on macroparasite infection.mathematical models of disease dynamics tend to assume that individuals within a population mix at random and so transmission is random, and yet, in reality social structure creates heterogeneous contact patterns. we investigated the effect of heterogeneity in host contact patterns on potential macroparasite transmission by first quantifying the level of assortativity in a socially structured wild rodent population (apodemus flavicollis) with respect to the directly-transmitted macroparasitic he ...200818814808
between-year variation and spatial dynamics of cryptosporidium spp. and giardia spp. infections in naturally infected rodent populations.prevalence and abundance of cryptosporidium spp. and giardia spp. infections were studied over the 8-year period in 3 species of rodents in n.e. poland (bank vole myodes glareolus-1523; yellow-necked mouse apodemus flavicollis- 638; common vole microtus arvalis- 419). prevalence was 53.8, 28.1 and 62.3% respectively for cryptosporidium spp. and 58.3, 24.4 and 74.2% respectively for giardia spp. prevalence and abundance of infection varied markedly across 8 years of the study with 1998 and 2002 b ...200818992178
incidence of various tick-borne microorganisms in rodents and ticks of central slovakia.in this study, we detected rickettsia helvetica, candidatus midichloria mitochondrii, anaplasma phagocytophilum, ehrlichia muris, candidatus neoehrlichia mikurensis, and bartonella sp. infections in wild rodents and ticks collected from the vegetation of central slovakia. the microorganisms were identified by pcr and sequencing. yellow-necked mice (apodemus flavicollis) were infected with e. muris and bartonella sp., while ticks ixodes ricinus collected from the vegetation were infected with r. ...200818999892
[the helminth fauna structure of wild rodents from differential sites of wrocław area].the parasite fauna of rodents was studied in the wrocław area from 2001 to 2005. the first location was irrigation fields (wrocław osobowice), the second--a water distribution area (wrocław mokry dwór). helminthological material was collected during parasitological examination of 447 specimens of wildlife rodents (belonging to 7 species of muridae). the helminth population and the helminth communities' structure were analyzed, their qualitative and quantitative characteristics were described by ...200819055070
heligmosomoides polygyrus reduces infestation of ixodes ricinus in free-living yellow-necked mice, apodemus flavicollis.free-living animals are usually inhabited by a community of parasitic species that can interact with each other and alter both host susceptibility and parasite transmission. in this study we tested the prediction that an increase in the gastrointestinal nematode heligmosomoides polygyrus would increase the infestation of the tick ixodes ricinus, in free-living yellow-necked mice, apodemus flavicollis. an extensive cross-sectional trapping survey identified a negative relationship between h. poly ...200919154651
absence of spermatozoal cd46 protein expression and associated rapid acrosome reaction rate in striped field mice (apodemus agrarius).in rodents, the cell surface complement regulatory protein cd46 is expressed solely on the spermatozoal acrosome membrane. ablation of the cd46 gene is associated with a faster acrosome reaction. sperm from apodemus flavicollis (yellow-necked field mice), a. microps (pygmy field mice) and a. sylvaticus (european wood mice) fail to express cd46 protein and exhibit a more rapid acrosome reaction rate than mus (house mice) or balb/c mice. a. agrarius (striped field mice) belong to a different apode ...200919371423
the hantaviral load in tissues of naturally infected rodents.hantaviruses cause a lifelong and asymptomatic infection in naturally infected hosts as well as in experimentally infected rodents. understanding the ecology and pathogenesis of hantaviruses requires an interdisciplinary research approach, which links laboratory experiments with results gained from field studies. although several studies report hantavirus persistence and tissue infection patterns for experimentally infected rodents, field data is very limited. for this reason, the aim of our stu ...200919397875
genetic diversity and geographic distribution of hantaviruses in russia.haemorrhagic fever with renal syndrome (hfrs) is the most prevalent zoonotic disease in russia. it is caused by several hantavirus species hosted by small rodents. we describe spatial and temporal patterns of hfrs incidence in the russian federation, and the geographic distribution of prevalent hantavirus species: puumala (puuv) and dobrava (dobv). partial sequencing of nucleocapsid and glycoprotein genes of 117 puuv strains and 78 dobv strains revealed several distinct genetic subgroups. the rn ...200919486318
patterns of orthopox virus wild rodent hosts in south germany.although cowpox virus (cpxv) infections in a variety of dead-end hosts have been investigated in germany for more than 50 years, data on species and geographical distribution of cpxv in reservoir hosts are sparse. here we present the first comprehensive study of 825 rodents that have been collected in bavaria, southern germany. in summary, six different rodent species (apodemus flavicollis, myodes glareolus, microtus arvalis, apodemus sylvaticus, microtus agrestis, and arvicola amphibius) were t ...200919492947
cd55 and cd59 protein expression by apodemus (field mice) sperm in the absence of cd46.the mammalian female reproductive tract has an abundance of complement components, which play a vital role in protection against genital pathogens. sperm may be protected against complement-mediated damage by complement regulatory proteins, including membrane cofactor protein (cd46), decay accelerating factor (cd55) and cd59. however, sperm from apodemus (field mice) do not express cd46 protein. the aim of the present study was to determine whether apodemus sperm may be protected against complem ...200919501411
spatial and temporal dynamics of lymphocytic choriomeningitis virus in wild rodents, northern italy.we determined the prevalence of infection with lymphocytic choriomeningitis virus (lcmv) among small mammals in northern italy and analyzed long-term dynamics of lcmv in a rodent population in the province of trento. lcmv is circulating among the most widespread and common wild rodent species in this area (apodemus flavicollis, myodes glareolus, and microtus arvalis); overall prevalence is 6.8%. during 2000-2006, intensive monitoring of lcmv in a population of yellow-necked mice (a. flavicollis) ...200919624914
six degrees of apodemus separation.social network analysis has been widely used to help understand the transmission of human diseases. its application to wildlife disease is very much in its infancy, largely because of the difficulty of recording contacts between wild animals. sarah perkins et al. have constructed contact networks for yellow-necked mice (apodemus flavicollis) in the italian alps, comparing networks derived from radio-tracking and mark-recapture data. they found that the method producing the most informative data ...200919682159
genetic detection of dobrava/belgrade virus in a czech patient with haemorrhagic fever with renal syndrome.in the summer of 2008, a 15-year-old boy was hospitalized in a paediatric intensive care unit in the czech republic. laboratory diagnosis of hantavirus infection was established by serological and molecular methods. sequence and phylogenetic analyses showed that the causative strain was dobrava/belgrade virus, which is genetically closer to strains associated with apodemus flavicollis rodents.201019832712
co-circulation of three pathogenic hantaviruses: puumala, dobrava, and saaremaa in hungary.hantaviruses (bunyaviridae) cause hemorrhagic fever with renal syndrome (hfrs) in eurasia and hantavirus (cardio)pulmonary syndrome (hcps) in the americas. hfrs is caused by hantaan virus (htnv), seoul virus (seov), dobrava virus (dobv), saaremaa virus (saav), and puumala virus (puuv). of those, only htnv is not present in europe. in recent years, hantaviruses, described in other parts of europe, were also detected at various locations in hungary. to study the genetic properties of hungarian han ...200919856478
validation of internal reference genes for quantitative real-time pcr in a non-model organism, the yellow-necked mouse, apodemus flavicollis.reference genes are used as internal standards to normalize mrna abundance in quantitative real-time pcr and thereby allow a direct comparison between samples. so far most of these expression studies used human or classical laboratory model species whereas studies on non-model organism under in-situ conditions are quite rare. however, only studies in free-ranging populations can reveal the effects of natural selection on the expression levels of functional important genes. in order to test the f ...200920030847
epidemiological study of hantavirus infection in the samara region of european russia.european russia is a highly endemic area of hemorrhagic fever with renal syndrome (hfrs), a rodent-borne zoonotic disease, caused by hantaviruses. in total, 145 small mammals of four species (myodes glareolus, apodemus flavicollis, a. agrarius, and a. uralensis) were trapped in the samara region of european russia in august 2005 and examined for the presence of hantavirus (hv). anti-hv antibodies were found in six of 68 (8.8%) m. glareolus and in one of 19 (5.3%) a. flavicollis by indirect immun ...200920046023
ljungan virus detected in bank voles (myodes glareolus) and yellow-necked mice (apodemus flavicollis) from northern italy.identified in 1998, ljungan virus (lv; picornaviridae) causes type 1 diabetes-like symptoms and myocarditis in bank voles (myodes glareolus) from sweden and denmark, and may be a zoonotic agent of several important diseases (e.g., intrauterine fetal death, type 1 diabetes, guillain-barré syndrome, and myocarditis). using a real-time reverse transcriptase-polymerase chain reaction assay and sequence analysis, we detected lv in bank voles, and for the first time, in yellow-necked mice (apodemus fl ...201020090041
the relative importance of host characteristics and co-infection in generating variation in heligmosomoides polygyrus fecundity.we examined the relative importance of intrinsic host factors and microparasite co-infection in generating variation in heligmosomoides polygyrus fecundity, a parameter that serves as a proxy for infectiousness. we undertook extensive trapping of apodemus flavicollis, the yellow-necked mouse in the woodlands of the italian alps and recorded eggs in utero from the dominant nematode species h. polygyrus, and tested for the presence of five microparasite infections. the results showed that sex and ...201020109249
heavy metal content in the femora of yellow-necked mouse (apodemus flavicollis) and wood mouse (apodemus sylvaticus) from different types of polluted environment in slovakia.heavy metal content in the femora of yellow-necked mouse (apodemus flavicollis) and wood mouse (apodemus sylvaticus) caught in different polluted biotopes of a low hill level in slovakia (nováky and kolínany) was investigated in the present study. length, weight and histological structure of mouse bones have also been analysed. according to our results, higher concentrations of cd, ni, fe, cu and zn were detected in the femora of a. flavicollis from kolínany area. similarly, we observed higher c ...201020135219
seasonality of the ectoparasite community of woodland rodents in a mazurian forest, poland.myodes glareolus and apodemus flavicollis support a large and diverse community of arthropod ectoparasites. this study of rodents in a mazurian woodland sampled at monthly intervals between 2007 and 2009 revealed an ectoparasite community composed of 2 species of tick, 1 louse, 9 flea species, 7 species of gamasid mites, 4 fur mites and one trombiculid mite. a strong seasonality was noted in the dynamics of the ectoparasite community, with the fur mite listrophorus sp. and the hypopus larva of a ...200920209812
[host and site-specific pattern of occurrence of digenetic trematodes in rodent communities from lower silesia, poland].trematodes of the class digenea are parasites with complex life cycles and often use small mammals as definitive hosts; however, they are usually not highly prevalent in this group of mammals. in our work the patterns of occurrence of digeneans parasitizing small mammals were analyzed. the surveys were conducted at four locations, i.e., irrigation fields (osobowice), a water distribution area (mokry dwor), recreational grounds (redzin forest), and nature reserve "stawy milickie". overall 894 rod ...200920209813
the ecology of bartonella spp. infections in two rodent communities in the mazury lake district region of poland.prevalence and abundance of bartonella spp. infections were studied over a 3-year period in woodland and grassland rodents in north-eastern poland. prevalence of bacterial infections was similar in the two rodent communities, with one leading host species in each habitat (46.3% in apodemus flavicollis versus 29.1% in myodes glareolus in forest, or 36.9% in microtus arvalis versus 13.7% in mi. oeconomus in grassland). prevalence/abundance of infections varied markedly across the 3 years with 2006 ...201020388232
tula virus in populations of small terrestrial mammals in a rural landscape.over 5 years (2000-2004), populations of small mammals from a rural landscape in southern moravia (czech republic) were investigated for the presence of tula virus (tulv) antigen using the elisa set hantagnost. in total, 1566 individuals from 10 species were examined. the prevalence in the common vole (microtus arvalis pallas 1778), the main reservoir of tulv, was 10% (n = 871). the prevalence of tulv antigen increases with its population numbers. the highest number of tulv antigen-positive comm ...201020420534
molecular evolution of trichuris muris isolated from different muridae hosts in europe.a phylogeographic study was carried out of trichuris muris, nematode parasitizing murinae rodents from the muridae family, isolated from four different hosts and from different geographical regions of europe by amplification and sequencing of the its1-5.8s-its2 fragment of the ribosomal dna. t. muris was found in the apodemus sylvaticus, apodemus flavicollis, mus domesticus, and rattus rattus rodents. the molecular results confirm the presence of dna polymorphisms among t. muris isolates from eu ...201020473527
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