Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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| qi-shao-shuang-gan, a combination of astragalus membranaceus saponins with paeonia lactiflora glycosides, ameliorates polymicrobial sepsis induced by cecal ligation and puncture in mice. | the present study was performed to investigate the anti-septic effects of qi-shao-shuang-gan (qssg), a combination of astragalus membranaceus saponins (sam) and paeonia lactiflora glycosides (gpl), in septic mice induced by cecal ligation and puncture. qssg was shown to elevate the survival rate of mice, decrease infiltration of polymorphonuclear leukocytes into livers and lungs, lower serum levels of myeloperoxidase, nitric oxide, and lactate dehydrogenase, and decrease mrna expressions of indu ... | 2011 | 20237952 |
| the effects of paeoniflorin on lps-induced liver inflammatory reactions. | paeoniflorin (pf), a monoterpene glucoside, is a primary bioactive component of paeony, the root extract of paeonia lactiflora. we tested the antioxidant effects of pf and its ability to prevent lipopolysaccharide (lps)-induced oxidative stress. we intraperitoneally administered pf (2.5, 5, or 10 mg/kg) to rats for 20 days. on day 21, we injected the rats with lps 4 h before sacrifice and measured serum levels of glutamate oxaloacetate transaminase, glutamate pyruvate transaminase, lactate dehyd ... | 2010 | 20607502 |
| bioactivity-guided isolation of 1,2,3,4,6-penta-o-galloyl-d-glucopyranose from paeonia lactiflora roots as a ptp1b inhibitor. | the inhibition of protein tyrosine phosphatase 1b (ptp1b) is of substantial interest for the treatment of type-2 diabetes mellitus. using an in vitro enzyme assay with human recombinant ptp1b 1,2,3,4,6-penta-o-galloyl-d-glucopyranose was isolated from the roots of paeonia lactiflora as an inhibitor of ptp1b, with an ic(50) value of 4.8 μm. additionally, 1 was shown to act as an insulin sensitizer in human hepatoma cells (hcc-1.2) at a concentration of 10 μm. thus, a potential new mechanism of ac ... | 2010 | 20806783 |
| platelet anti-aggregatory and blood anti-coagulant effects of compounds isolated from paeonia lactiflora and paeonia suffruticosa. | the roots of two paeoniaceae family members have long been used as traditional medicines in korea, china, and japan. dry roots of paeonia lactiflora and dry root bark of p. suffruticosa are used under the traditional names of paeoniae radix and moutan cortex, respectively. both paeoniae radix and moutan cortex have been used as remedies for cardiovascular diseases, for improving blood circulation, or for other uses. it was postulated that both plants may contain common active constituents that c ... | 2010 | 20824965 |
| in vitro bace-1 inhibitory activity of resveratrol oligomers from the seed extract of paeonia lactiflora. | a new resveratrol oligomer (1) together with eight related components (2- 9) were isolated from the seed extract of paeonia lactiflora (paeoniaceae) as active principles responsible for the inhibition of beta-site app-cleaving enzyme 1 (bace-1) in vitro. the chemical structure of 1 was established as (-)-7a,8a- cis- ε-viniferin with the aid of spectroscopic analyses including noesy experiments. all isolated resveratrol oligomers (1- 9) demonstrated significant inhibition on baculovirus-expressed ... | 2010 | 20890809 |
| protective effect of a molecular chaperone inducer, paeoniflorin, on the hcl- and ethanol-triggered gastric mucosal injury. | we previously found that paeoniflorin, a major constituent of paeonia lactiflora pall, could induce heat shock proteins (hsps) in cultured mammalian cells without apparent toxicity (yan et al. 2004). we here investigated the induction of hsps by paeoniflorin in mouse stomach and the effect of paeoniflorin on the hcl- and ethanol-triggered gastric mucosal injury in mouse. | 2010 | 21167840 |
| comparative pharmacokinetics of paeoniflorin in plasma of vascular dementia and normal rats orally administrated with danggui-shaoyao-san or pure paeoniflorin. | danggui-shaoyao-san (dss), a traditional chinese medicinal prescription, is clinically used for the treatment of vascular dementia (vd). this study compared the pharmacokinetics of paeoniflorin, the main active ingredients in paeonia lactiflora pall, in vd and normal rats administrated with dss or pure paeoniflorin. the absorptions of paeoniflorin in both vd and normal group of rats were better when orally administrated with dss than that with pure paeoniflorin, which justified the combined use ... | 2010 | 21185921 |
| peoniflorin suppresses tumor necrosis factor-α induced chemokine production in human dermal microvascular endothelial cells by blocking nuclear factor-κb and erk pathway. | peoniflorin (pf) extracted from the root of paeonia lactiflora pall displays anti-inflammation and antioxidant properties in several animal models. chemokines are vital for directing the movement of circulating leukocytes to the sites of inflammation and are involved in the pathogenesis of various inflammatory skin diseases. herein, we investigated the effects and potential mechanisms of pf on tumor necrosis factor-α (tnf-α) induced chemokine production in human dermal microvascular endothelial ... | 2010 | 21190116 |
| paeonia lactiflora pall inhibits bladder cancer growth involving phosphorylation of chk2 in vitro and in vivo. | extracts of paeonia lactiflora pall (rpa), a traditional chinese medicines has been shown to treat cancers. | 2011 | 21396995 |
| effects of total glucosides from paeony (paeonia lactiflora pall) roots on experimental atherosclerosis in rats. | total glucosides of paeony (tgp), compounds extracted from the roots of paeonia lactiflora pall, have been used as an anti-inflammatory drug for the treatment of rheumatoid arthritis (ra) in china. inflammation plays a critical role in the development of atherosclerotic vascular disease. risk of cardiovascular diseases is significantly higher in patients with ra than in normal population. it has a great significance to study the effects of tgp on atherosclerosis. | 2011 | 21453765 |
| identification of novel pregnane x receptor activators from traditional chinese medicines. | to investigate the ability of traditional chinese medicines (tcms) and their bioactive compounds to activate pregnane x receptor (pxr) signalling pathway. | 2011 | 21524698 |
| anti-inflammatory and immunomodulatory effects of paeonia lactiflora pall., a traditional chinese herbal medicine. | in china, korea, and japan, a decoction of the dried root without bark of paeonia lactiflora pall. has been used in the treatment of rheumatoid arthritis, systemic lupus erythematosus, hepatitis, dysmenorrhea, muscle cramping and spasms, and fever for more than 1200 years. a water/ethanol extract of the root is now known as total glucosides of peony (tgp), which contains more than 15 components. paeoniflorin is the most abundant ingredient and accounts for the pharmacological effects observed wi ... | 2011 | 21687505 |
| pharmacological evaluation of insulin mimetic novel suppressors of pepck gene transcription from paeoniae rubra radix. | paeoniae rubra radix (root of paeonia lactiflora) has been frequently employed in traditional chinese medicine (tcm) as and anti-diabetic therapy to enhance blood circulation and dissipate stasis. | 2011 | 21704145 |
| metabonomic study on chronic unpredictable mild stress and intervention effects of xiaoyaosan in rats using gas chromatography coupled with mass spectrometry. | ethnopharmacology: xiaoyaosan (xys), a famous chinese prescription, composed of radix bupleuri (bupleurum chinense dc.), radix angelicae sinensis (angelica sinensis (oliv.) diels), radix paeoniae alba (paeonia lactiflora pall.), rhizoma atractylodis macrocephalae (atractylodes macrocephala koidz.), poria (poria cocos (schw.) wolf), radix glycyrrhizae (glycyrrhiza uralensis fisch.), herba menthae (mentha haplocalyx briq.), and rhizoma zingiberis recens (zingiber officinale rosc.), has been widely ... | 2011 | 21718771 |
| paeoniflorin protects against lipopolysaccharide-induced acute lung injury in mice by alleviating inflammatory cell infiltration and microvascular permeability. | objective: the present study aims to explore the effects of paeoniflorin (pf), a monoterpene glycoside isolated from the roots of paeonia lactiflora pallas, on acute lung injury (ali) and the possible mechanisms. materials and method: ali was induced in mice by an intratracheal instillation of lipopolysaccharide (lps, 1 mg/kg), and pf was injected intraperitoneally 30 min prior to lps administration. after 24 h, lung water content, histology, microvascular permeability and proinflammatory cytoki ... | 2011 | 21744312 |
| protective effects of peoniflorin against hydrogen peroxide-induced oxidative stress in human umbilical vein endothelial cells. | peoniflorin (pf), extracted from the root of paeonia lactiflora pall., has been reported to have anti-inflammation and antioxidant effects in several animal models. herein, we investigated the protective effects of pf against hydrogen peroxide (h(2)o(2))-induced oxidative damage in human umbilical vein endothelial cells (huvecs). huvecs were treated by h(2)o(2) (240 µmol/l) with or without pf. pf significantly increased the percent cell viability of huvecs injured by h(2)o(2) using the 3-(4,5-di ... | 2011 | 21777057 |
| influence of paeonia lactiflora roots extract on camp-phosphodiesterase activity and related anti-inflammatory action. | background: paeonia lactiflora root (baishao in chinese) is a commonly used herb in tcm. research has shown baishao to have positive pharmacological actions, including, particularly, anti-inflammatory properties. in this paper we studied the influence of baishao extract on camp-phosphodiesterase (pde) activity and related anti-inflammatory action to identify new pharmacologic action for its clinically widespread use. methods: pde activity was calculated by camp change examined with hplc, respira ... | 2011 | 21782011 |
| paeoniflorin inhibits function of synoviocytes pretreated by ril-1+¦ and regulates ep(4) receptor expression. | ethnopharmacological relevance: to investigate the effect of the paeoniflorin (pae), a main active component of total glucosides of paeony (tgp) extracted from the root of paeonia lactiflora, on regulation of synoviocytes cultured from rats collagen-induced arthritis (cia) in vitro. materials and methods: cia was induced in male sprague-dawley rats immunized with chicken type ii collagen (ccii) in freund's complete adjuvant. the levels of interleukin-1 (il-1), tumor necrosis factor +¦ (tnf-+¦), ... | 2011 | 21840386 |
| paeoniflorin reduced acute toxicity of aconitine in rats is associated with the pharmacokinetic alteration of aconitine. | ethnopharmacological relevance: to investigate the influence of paeoniflorin (major bioactive component of paeonia lactiflora pall.) on the pharmacokinetic behavior of aconitine (major toxic and bioactive component of aconitum carmichaeli debx.) and potential detoxifying effect of paeoniflorin on the acute toxicity of aconitine, which may provide in depth understanding to the toxicity reduction effect of paeonia lactiflora to aconitum carmichaeli. materials and methods: ultra high performance li ... | 2011 | 21930193 |
| a standardized extract from paeonia lactiflora and astragalus membranaceus attenuates liver fibrosis induced by porcine serum in rats. | paeonia lactiflora and astragalus membranaceus are two popular traditional chinese medicines, commonly used in chinese herb prescription to treat liver disease. the extract prepared from the roots of paeonia lactiflora and astragalus membranaceus (pae) demonstrated better hepatoprotective activity than the herbs used individually as shown in our previous studies. this study was carried out to investigate the effects of pae on liver fibr ... | 2011 | 22109673 |
| Anti-depressant-like effect of peony: a mini-review. | Context: Depression is a common psychiatric disorder, yet the clinical efficacy of antidepression therapies is unsatisfactory. Thus, the search for new anti-depressants continues, and natural products remain a promising source of new therapeutic agents. The root part of Paeonia lactiflora Pall. (Ranunculaceae), known as peony, is often used in Chinese herbal prescriptions for the treatment of depression-like disorders. Objectives: The objective of this review is to provide scientific evidence ... | 2012 | 22196583 |
| old formula, new rx: the journey of phy906 as cancer adjuvant therapy. | phy906, is a decoction of a mixture of the four herbs scutellaria baicalensis geori, glycyrrhiza uralensis fisch, paeonia lactiflora pall, and ziziphus jujuba mill. a combination of these four herbs has been in continuous use in traditional chinese medicine for over 1800 years for treating a variety of gastrointestinal distress such as diarrhea, cramps, nausea, vomiting etc. | 2012 | 22326673 |
| food- and gender-dependent pharmacokinetics of paeoniflorin after oral administration with samul-tang in rats. | samul-tang (si-wu-tang in chinese, shimotsu-to in japanese), widely used in eastern asia, is composed of angelica gigas (angelicae gigantis radix), cnidium officinale (cnidii rhizoma), paeonia lactiflora (paeonia radix) and rehmannia glutinosa (rehmanniae radix preparata). paeoniflorin, one of active components in samul-tang has anti-platelet, anti-inflammation, anti-cancer and neuroprotective properties. however, there is no information about the effects of gender and food intake on the pharmac ... | 2012 | 22543167 |
| growth-inhibiting effects of paeonia lactiflora root steam distillate constituents and structurally related compounds on human intestinal bacteria. | the growth-inhibiting activities of paeonia lactiflora (paeoniaceae) root steam distillate constituents and structurally related compounds against nine harmful intestinal bacteria and eight lactic acid-producing bacteria were compared with those of two antibiotics, amoxicillin and tetracycline. thymol, α-terpinolene, (-)-perilla alcohol and (1r)-(-)-myrtenol exhibited high to extremely high levels of growth inhibition of all the harmful bacteria, whereas thymol and α-terpinolene (except for lact ... | 2012 | 22805939 |
| growth-inhibiting, bactericidal, and urease inhibitory effects of paeonia lactiflora root constituents and related compounds on antibiotic-susceptible and -resistant strains of helicobacter pylori. | an assessment was made of the growth-inhibiting, bactericidal, and urease inhibitory activities of paeonol (pa), benzoic acid (ba), methyl gallate (mg), and 1,2,3,4,6-penta-o-galloyl-β-d-glucopyranose (pgg) identified in paeonia lactiflora root, structurally related compounds, and four antibiotics toward three reference strains and four clinical isolates of helicobacter pylori using broth dilution bioassay and western blot. ba and pa showed strong bactericidal effect at ph 4, while mg and pgg we ... | 2012 | 22891951 |
| inhibitory effects of korean indigenous plants on tyrosinase and melanogenesis. | to search for new depigmenting cosmetic ingredients from korean herbal extracts of traditional korean medicines (tkms), we screened about 17 tkm extracts collected in the republic of korea. samples were prepared from the natural plants, including medicinal plants such as chrysanthemum indicum (flower), using methanol, methylene chloride, ethyl acetate (etoac), n-butyl alcohol, and water as the extraction and/or the partitioning solvents. we then tested their inhibitory effects on melanogenesis b ... | 2013 | 23578837 |
| anti-viral activity of water extract of paeonia lactiflora pallas against human respiratory syncytial virus in human respiratory tract cell lines. | paeonia lactiflora pallas (p. lactiflora, ranunculaceae) is a common ingredient of sheng-ma-ge-gen-tang (smggt; shoma-kakkon-to) and ge-gen-tang (ggt; kakkon-to). smggt and ggt are different prescriptions of traditional chinese medicine with different ingredients designed for airway symptoms. both smggt and ggt have anti-viral activity against human respiratory syncytial virus (hrsv). therefore, p. lactiflora was hypothesized to be the effective ingredient of both smggt and ggt against hrsv. how ... | 2013 | 23711143 |
| pharmacokinetic comparisons of two different combinations of shaoyao-gancao decoction in rats: competing mechanisms between paeoniflorin and glycyrrhetinic acid. | shaoyao-gancao decoction (sgd), a well-known traditional chinese medicine prescription, is a combination of radix paeoniae alba (paeonia lactiflora pall, root) and glycyrrhizae uralensis (glycyrrhiza uralensis fisch., root and rhizome, honeyed) for spasmolysis and emergency pain relief. paeoniflorin (pf) and glycyrrhetinic acid (ga) are two typical active components of sgd for pain relief. | 2013 | 23867078 |
| a standardized extract from paeonia lactiflora and astragalus membranaceus induces apoptosis and inhibits the proliferation, migration and invasion of human hepatoma cell lines. | paeonia lactiflora and astragalus membranaceus are two traditional chinese medicines, which are commonly used in chinese herb prescription to treat liver diseases. the protective effects of the extract prepared from the roots of paeonia lactiflora and astragalus membranaceus (pae) on liver fibrosis have been demonstrated in previous studies. however, its effect on hepatocellular carcinoma (hcc) has not been investigated to date. in this study, the effects of pae on the apoptosis, proliferation, ... | 2013 | 24002667 |
| identification of multiple ingredients for a traditional chinese medicine preparation (bu-yang-huan-wu-tang) by liquid chromatography coupled with tandem mass spectrometry. | bu-yang-huan-wu-tang (byhwt) is a popular traditional chinese medicine formula consisting of seven herbal medicines (astragalus membranaceus, angelica sinensis, paeonia lactiflora, ligusticum chuanxiong, carthamus tinctorius, amygdalus persica and pheretima aspergillum), that has been used in china for centuries to overcome stroke-induced disability. to ensure the consistency of quality, a reliable analytical method is required, therefore, we developed a liquid chromatography with tandem mass sp ... | 2013 | 24036516 |
| characterization of the anti-influenza activity of the chinese herbal plant paeonia lactiflora. | bai shao (bs, the root of paeonia lactiflora pall.), a common chinese herb in many recipes used to treat viral infection and liver diseases, is recognized for its ability to nourish menstruation, its yin convergence, and as an antiperspirant. however, the mechanism and components for its antiviral function remain to be elucidated. in this study, an ethanolic extract of bs was further partitioned into aqueous and organic parts (eaex) for in vitro functional study and in vivo efficacy testing. eae ... | 2014 | 24762393 |
| in vitro synergistic antioxidant activity and identification of antioxidant components from astragalus membranaceus and paeonia lactiflora. | many traditionally used herbs demonstrate significantly better pharmacological effects when used in combination than when used alone. however, the mechanism underlying this synergism is still poorly understood. this study aimed to investigate the synergistic antioxidant activity of astragalus membranaceus (ame) and paeonia lactiflora (pl), and identify the potential antioxidant components by 1,1-diphenyl-2-picrylhydrazine (dpph) radical spiking test followed by a high performance liquid chromato ... | 2014 | 24816851 |
| chemical interaction between paeonia lactiflora and glycyrrhiza uralensis, the components of jakyakgamcho-tang, using a validated high-performance liquid chromatography method: herbal combination and chemical interaction in a decoction. | the herbal combination is the basic unit of a herbal formula that affects the chemical characteristics of individual herbs. in the present study, a method of simultaneous determination of the 11 marker compounds in jakyakgamcho-tang was developed using high-performance liquid chromatography with photodiode array detection. the validated analytical method was successfully applied to approach the chemical interaction between paeonia lactiflora and glycyrrhiza uralensis in co-decoction. in p. lacti ... | 2014 | 25044951 |
| an emerging translational model to screen potential medicinal plants for nephrolithiasis, an independent risk factor for chronic kidney disease. | pharmacological therapy for urolithiasis using medicinal plants has been increasingly adopted for the prevention of its recurrence. a drosophila melanogaster model developed for translational research of urolithiasis was applied to evaluate agents with potential antilithic effects and calcium oxalate (caox) formation. potential antilithic herbs were prepared in a mixture of food in a diluted concentration of 5,000 from the original extract with 0.5% ethylene glycol (eg) as the lithogenic agent. ... | 2014 | 25097661 |
| dynamic analysis of the endogenous metabolites in depressed patients treated with tcm formula xiaoyaosan using urinary (1)h nmr-based metabolomics. | xiaoyaosan (xys), one of the best-known traditional chinese medicine prescriptions with a long history of use, is composed of bupleurum chinense dc., paeonia lactiflora pall., poria cocos (schw.) wolf, angelica sinensis (oliv.) diels, zingiber officinale rosc., atractylodes macrocephala koidz., glycyrrhiza uralensis fisch., and mentha haplocalyx briq. for centuries, xys has been widely used in china for the treatment of mental disorders such as depression. however, the complicated mechanism unde ... | 2014 | 25448502 |
| anti-inflammatory effects of huangqin tang extract in mice on ulcerative colitis. | huangqintang (hqt) is a traditional chinese formula which is composed of scutellaria baicalensis georgi, paeonia lactiflora pall, glycyrrhiza uralensis fisch, and ziziphus jujube mill. hqt has been used in china for a wide range of disorders, especially in gastrointestinal inflammation with symptoms of nausea, vomiting, diarrhea, abdominal cramps and so on. | 2015 | 25576893 |
| plant-derived natural medicines for the management of depression: an overview of mechanisms of action. | depression is a serious widespread psychiatric disorder that affects approximately 17% of people all over the world. exploring the neurological mechanisms of the antidepressant activity of plant-derived agents could have a crucial role in developing natural drugs for the management of depression. the aim of the present study is to review the neurological mechanisms of action of antidepressant plants and their constituents. for this purpose, electronic databases, including pubmed, science direct, ... | 2015 | 25719303 |
| traditional herbal formula jakyakgamcho-tang (paeonia lactiflora and glycyrrhiza uralensis) impairs inflammatory chemokine production by inhibiting activation of stat1 and nf-κb in hacat cells. | a traditional herbal formula jakyakgamcho-tang (jygct; paeonia lactiflora and glycyrrhiza uralensis) has been used for treatment of backache, muscle pain, acute abdominal pain, neuralgia, bronchial asthma, and painful peripheral neuropathy in oriental medicine. we report on our experiments using the hacat human keratinocyte cell line showing that a traditional herbal formula jygct has inhibitory effects on inflammatory responses in skin. stimulation with tumour necrosis factor-alpha (tnf-α) and ... | 2015 | 25765840 |
| molecular identification of botrytis cinerea, botrytis paeoniae and botrytis pseudocinerea associated with gray mould disease in peonies (paeonia lactiflora pall.) in southern chile. | in chile, the peony is the most important ornamental flower exported from the country. gray mould is a phytopathological problem of this crop. this disease is caused by botrytis cinerea and botrytis paeoniae. | 2016 | 25982419 |
| the traditional herbal medicine, ge-gen-tang, inhibits pacemaker potentials by nitric oxide/cgmp dependent atp-sensitive k(+) channels in cultured interstitial cells of cajal from mouse small intestine. | ge-gen-tang (ggt) is a traditional chinese medicinal formula composed of puerariae radix (pueraria lobata ohwi), ephedrae herba (ephedra sinica stapf), cinnamomi ramulus (cinnamomum cassia blume), paeoniae radix (paeonia lactiflora pallas), glycyrrhizae radix preparata (glycyrrhiza uralensis fischer), zingiberis rhizoma (zingiber officinale roscoe), and zizyphi fructus (ziziphus jujuba mill. var. inermis rehder) and is widely used to ameoliorate the symptoms of gastrointestinal (gi) disorders re ... | 2015 | 26003723 |
| prescription of chinese herbal medicine in pattern-based traditional chinese medicine treatment for depression: a systematic review. | traditional chinese medicine (tcm) treatments are often prescribed based on individuals' pattern diagnoses. a systematic review of randomized controlled trials in chinese and english literatures on tcm pattern-based treatment for depression has therefore been conducted. a total of 61 studies, 2504 subjects, and 27 tcm patterns were included. due to the large variation of tcm pattern among participants, we only analyzed the top four commonly studied tcm patterns: liver qi depression, liver depres ... | 2015 | 26180532 |
| digital gene expression analysis to screen disease resistance-relevant genes from leaves of herbaceous peony (paeonia lactiflora pall.) infected by botrytis cinerea. | herbaceous peony (paeonia lactiflora pall.) is a well-known traditional flower in china and is widely used for landscaping and garden greening due to its high ornamental value. however, disease spots usually appear after the flowering of the plant and may result in the withering of the plant in severe cases. this study examined the disease incidence in an herbaceous peony field in the yangzhou region, jiangsu province. based on morphological characteristics and molecular data, the disease in thi ... | 2015 | 26208357 |
| the antithrombotic effect of rsnk in blood-stasis model rats. | reduction of sheng-nao-kang decoction (rsnk), composed of salvia miltiorrhiza bge., ligusticum chuanxiong hort., astragalus membranaceus (fisch.) bunge., pueraria lobata (willd.) ohwi., paeonia lactiflora pall. and panax notoginseng (burk.) f. h. chen., is a modified traditional chinese medicinal formula of sheng-nao-kang pill preparation, which has been investigated its protective effect on focal cerebral ischemia-reperfusion injury in rat in our previous report. | 2015 | 26216512 |
| the difference between blood-associated and water-associated herbs of danggui-shaoyao san in theory of tcm, based on serum pharmacochemistry. | danggui-shaoyao san (dss) is a famous chinese formula for activating blood circulation and promoting urination. this study was to investigate the difference of material basis between a blood-associated herbs group and a water-associated herbs group. according to the theory of traditional chinese medicine, the formula can be divided into a blood-associated herbs group (angelica sinensis, paeonia lactiflora and ligusticum chuanxiong) and a water-associated herbs group (atractylodes macrocephala, a ... | 2016 | 26270156 |
| identification of mirnas responsive to botrytis cinerea in herbaceous peony (paeonia lactiflora pall.) by high-throughput sequencing. | herbaceous peony (paeonia lactiflora pall.), one of the world's most important ornamental plants, is highly susceptible to botrytis cinerea, and improving resistance to this pathogenic fungus is a problem yet to be solved. micrornas (mirnas) play an essential role in resistance to b. cinerea, but until now, no studies have been reported concerning mirnas induction in p. lactiflora. here, we constructed and sequenced two small rna (srna) libraries from two b. cinerea-infected p. lactiflora cultiv ... | 2015 | 26393656 |
| analysis of codon usage patterns in herbaceous peony (paeonia lactiflora pall.) based on transcriptome data. | codon usage bias, which exists in many genomes, is mainly determined by mutation and selection. to elucidate the genetic features and evolutionary history of herbaceous peony (paeonia lactiflora), a well-known symbol of prosperity in china, we examined synonymous codon usage in 24,216 reconstructed genes from the p. lactiflora transcriptome. the mean gc content was 44.4%, indicating that the nucleotide content of p. lactiflora genes is slightly at rich and gc poor. the p. lactiflora genome has a ... | 2015 | 26506393 |
| [clinical observation of breast hyperplasia treated with auricular point sticking therapy and xiaopijian]. | to observe the efficacy difference in the treatment of breast hyperplasia between the combined therapy of auricular point sticking and xiaopijian and the simple application of xiaopijian. | 2015 | 26571890 |
| influence of herbal combinations on the extraction efficiencies of chemical compounds from cinnamomum cassia, paeonia lactiflora, and glycyrrhiza uralensis, the herbal components of gyeji-tang, evaluated by hplc method. | during decoction process, the ingredients of herbal formula interact with each other, such that therapeutic properties and chemical extraction characteristics are altered. the crude drugs, cinnamomum cassia (cc), paeonia lactiflora (pl), and glycyrrhiza uralensis (gu), are the main herbal constituents of gyeji-tang, a traditional herbal formula. to evaluate the chemical interaction between cc, pl, and gu during the course of decoction, quantification of 16 marker compounds in the herbal decoctio ... | 2016 | 27399342 |
| danggui-shaoyao-san: new hope for alzheimer's disease. | danggui-shaoyao-san (dss), also called toki-shakuyaku-san (tj-23) or dangguijakyak-san (djs), is a well-known herbal formula (angelica sinensis (oliv.) diels., ligusticum chuanxiong hort., paeonia lactiflora pall., poria cocos (schw.) wolf, alisma orientalis (sam.) juzep., atractylodes macrocephala koidz.), which has been widely used in oriental countries for the treatment of various gynecological diseases. recent studies show that dss has an effect on free radical-mediated neurological diseases ... | 2016 | 27493835 |
| neuroprotective effect of a novel chinese herbal decoction on cultured neurons and cerebral ischemic rats. | historically, traditional chinese medicine has been widely used to treat stroke. based on the theory of chinese medicine and the modern pharmacological knowledge of herbal medicines, we have designed a neuroprotective formula called post-stroke rehabilitation (psr), comprising seven herbs - astragalus membranaceus (fisch.) bunge, salvia miltiorrhiza bunge, paeonia lactiflora pall., cassia obtusifolia l., ligusticum chuanxiong hort., angelica sinensis (oliv.) diels, and glycyrrhiza uralensis fisc ... | 2016 | 27814708 |
| ameliorating effects of herbal formula hemomine on experimental subacute hemorrhagic anemia in rats. | hemomine (hm) is an herbal mixture consisting of 5 varieties of the hematopoietic herbal extracts (angelica gigas nakai, cnidium officinale makino, paeonia lactiflora pall., rehmannia glutinosa liboschitz ex stueudel, glycyrrhiza uralensis fischer). | 2017 | 28089715 |
| paeonia lactiflora inhibits cell wall synthesis and triggers membrane depolarization in candida albicans. | fungal cell walls and cell membranes are the main targets of antifungals. in this study, we report on the antifungal activity of an ethanol extract from paeonia lactiflora against candida albicans, showing that the antifungal activity is associated with the synergistic actions of preventing cell wall synthesis, enabling membrane depolarization, and compromising permeability. first, it was shown that the ethanol extract from p. lactiflora was involved in damaging the integrity of cell walls in c. ... | 2017 | 28100900 |
| jakyakgamcho-tang and its major component, paeonia lactiflora, exhibit potent anti-glycation properties. | advanced glycation end products (ages) have been implicated in the pathogenesis of diabetes and other age-related diseases. age inhibitors or breakers, such as aminoguanidine and alagebrium, have been proposed as therapeutic agents for age-related disorders. jakyakgamcho-tang (jgt) is a well-known traditional herbal formula, which consists of the radix of paeonia lactiflora pallas (pr) and the radix and rhizome of glycyrrhiza uralensis fisch (gr). the purpose of this study was to evaluate the in ... | 2016 | 28150470 |