Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| dental implant infections. | dental implants provide a restorative tool to support crowns, bridge abutments, and removable dentures. osseointegrated implants are titanium posts that are surgically implanted in alveolar bone. a tight immobile bond (osseointegration) forms between bone and titanium, and prosthetic and restorative fixtures are attached to the implants. titanium implants differ from natural teeth, which may make them more susceptible to mechanical stress. a small proportion of implants are not successful and ma ... | 1997 | 9310682 |
| periodontitis patient and the spouse: periodontal bacteria before and after treatment. | suspected periodontal pathogens can be transmitted between spouses. the treatment response may be unsuccessful in periodontitis patients, if the spouse harbors these bacteria. the aim of the present 6-month follow-up study was to clarify whether the microbiological treatment outcome of periodontitis patients is related to the detection of suspected periodontal pathogens in the saliva of the spouse. 10 patients with advanced periodontitis and their spouses were included in the study. the patients ... | 1997 | 9442426 |
| microbial complexes in subgingival plaque. | it has been recognized for some time that bacterial species exist in complexes in subgingival plaque. the purpose of the present investigation was to attempt to define such communities using data from large numbers of plaque samples and different clustering and ordination techniques. subgingival plaque samples were taken from the mesial aspect of each tooth in 185 subjects (mean age 51 +/- 16 years) with (n = 160) or without (n = 25) periodontitis. the presence and levels of 40 subgingival taxa ... | 1998 | 9495612 |
| effect of red blood cells on the growth of porphyromonas endodontalis and microbial community development. | establishment of a microbial community in the root canal system depends on numerous factors, of which nutrient availability may be one of the most important. we hypothesized that the presence of red blood cells or hemoglobin in this environment could cause shifts in microbial composition of communities, resulting in organisms such as porphyromonas endodontalis becoming more dominant. an in vitro model system using mixed, batch cultures was performed with the bacteria p. endodontalis, fusobacteri ... | 1998 | 9573801 |
| prevalence of peptostreptococcus micros morphotypes in patients with adult periodontitis. | the prevalence of the smooth and rough colonial morphotypes of peptostreptococcus micros was examined with culture technique in 123 patients with adult periodontitis (age 24-68 years). of all subgingival samples, 91% contained the smooth morphotype of p. micros. the smooth morphotype constituted a mean percentage of the total anaerobic viable biota of 6.0%, with a range of 0.02-35.7%. of these samples, 49% contained colonies of the rough morphotype as well, with a mean percentage of the total an ... | 1998 | 9573826 |
| [subacute infectious endocarditis in prosthetic valve by peptostreptococcus micros]. | 1998 | 9586375 | |
| aminopeptidase activities in peptostreptococcus spp. are statistically correlated to gelatin hydrolysis. | one hundred peptostreptococcus isolates from five species were assessed for their ability to hydrolyze gelatin. most peptostreptococcus magnus (95.8%) and peptostreptococcus micros isolates (79.0%) hydrolyzed gelatin in contrast to peptostreptococcus asaccharolyticus (8.0%), peptostreptococcus anaerobius (10.0%), and peptostreptococcus prevotii isolates (16.7%). gelatin hydrolysis in peptostreptococcus magnus and peptostreptococcus micros isolates correlated (r = 0.80; p = 0.0019) with more amin ... | 1998 | 9606913 |
| oral microbiota in smokers and non-smokers in natural and experimentally-induced gingivitis. | the present study primarily aimed at investigating the oral microbiota in smokers and non-smokers with established gingivitis and monitoring its composition during experimental gingivitis. secondly, it aimed at examining whether the composition of the microbiota is associated with different levels of gingival inflammation during this experimental gingivitis trial. for this purpose, 25 non-dental university students with gingivitis were recruited. 11 subjects were smokers and 14 were non-smokers. ... | 1998 | 9722273 |
| microorganisms in closed periapical lesions. | the purpose of this study was to investigate the microorganisms of strictly selected closed periapical lesions associated with both refractory endodontic therapy and pulpal calcification. definitive criteria were established that assured complete clinical isolation of the periapical lesion from the oral and periodontal environment. a total of 13 criteria-referenced lesions were selected from 70 patients with endodontic surgical indications. a well controlled culturing method was used in all case ... | 1998 | 9823127 |
| additional clinical and microbiological effects of amoxicillin and metronidazole after initial periodontal therapy. | the aims of this study were to evaluate the clinical and microbiological effects of initial periodontal therapy (it) and to determine the additional effects of systemic amoxicillin (flemoxin solutab) 375 mg tid plus metronidazole 250 mg tid therapy, in patients with adult actinobacillus actinomycetemcomitans (aa)-associated periodontitis in conjunction with either porphyromonas gingivalis (pg), bacteroides forsythus (bf) and/or prevotella intermedia (pi). in addition the adverse effects of the a ... | 1998 | 9846793 |
| proficiencies of three anaerobic culture systems for recovering periodontal pathogenic bacteria. | anaerobic culture is employed routinely in the primary isolation of periodontal pathogenic bacteria. however, little or no data exist on the relative abilities of the coy anaerobic chamber (coy laboratory products, grass lake, mich.), the gaspak (becton dickinson microbiology systems, cockeysville, md.), and the anaeropack (mitsubishi gas chemical america, inc., new york, n.y.) systems to grow important periodontal species, including porphyromonas gingivalis, prevotella intermedia/nigrescens, ba ... | 1999 | 9854085 |
| trichomonas tenax empyema in an immunocompromised patient with advanced cancer. | a 53-year-old male acromegalic patient with advanced rectal adenocarcinoma developed pleuritis in the course of cobalt irradiation, steroid treatment and chemotherapy. examination of drained pleural fluid demonstrated numerous motile organisms, which were identified as trichomonas tenax by giemsa staining. peptostreptococcus micros was also detected in the cultures of pleural fluid and blood. treatment with metronidazole successfully eliminated the protozoa and cured the pyothorax. | 1998 | 9879561 |
| pathogenicity of peptostreptococcus micros morphotypes and prevotella species in pure and mixed culture. | recently, an atypical rough colony morphotype of peptostreptococcus micros, a species which is found in ulcerating infections, including periodontitis, was isolated. the virulence of morphotypes alone and in combination with prevotella intermedia and p. nigrescens was investigated both in vivo and in vitro. all strains tested induced abscesses containing fluid pus in a mouse skin model, and lesions caused by monocultures of the rough morphotype strains of p. micros were statistically significant ... | 1998 | 9879956 |
| [clinical evaluation of lung abscess diagnosed by transtracheal aspiration]. | we have diagnosed lung abscess according to findings of infiltration with cavity formation on chest x-ray and/or ct-scan and pathogens isolated from transtracheal aspirates. we evaluated the clinical features of 20 patients with lung abscess (18 males and 2 females, mean age; 54.3 years). diabetus mellitus and periodontal diseases were prominent underlying diseases in patients with lung abscess. cough was complained in 13 patients, chest or back pain in 9, purulent sputum in 8 and hemosputum in ... | 1998 | 9884505 |
| isolation of fusobacterium necrophorum from cancrum oris (noma). | a study of the predominant microflora in active sites of noma (cancrum oris) lesions was carried out in eight noma patients 3-15 years of age in sokoto state in northwestern nigeria. paper point sampling and conventional anaerobic microbiologic techniques were used. fusobacterium necrophorum was recovered from 87.5% of the noma lesions. oral microorganisms included prevotella intermedia, alpha-hemolytic streptococci, and actinomyces spp. which were isolated from 75.0%, 50.0%, and 37.5% of the pa ... | 1999 | 9988340 |
| elastase activity of anaerobes isolated from amniotic fluid with preterm premature rupture of membranes. | a total of 131 anaerobes isolated from amniotic fluid with preterm premature rupture of membranes and stored were examined for elastolytic activity by the method described by williams et al (lett appl microbiol 1988;7:173-6). | 1999 | 9988804 |
| relationship of the subgingival microbiota to a chairside test for aspartate aminotransferase in gingival crevicular fluid. | the aim of the present study was to evaluate the association between the occurrence of certain specific periodontal pathogens and aspartate aminotransferase (ast) levels in gingival crevicular fluid (gcf). | 1999 | 10052771 |
| clinical and microbiological characteristics of smokers with early onset periodontitis. | cigarette smoking is a potential risk factor which has recently been associated with periodontal disease progression. the objective of this study was to compare the microbial profile of smokers and non-smokers in a group of patients with early onset periodontitis. the study population consisted of 60 healthy individuals, 40 males and 20 females aged 22 to 35 yr, exhibiting early onset periodontitis. thirty patients were smokers (30.9 cigarettes/d) and 30 non-smokers. smokers had a higher proport ... | 1999 | 10086883 |
| the microbiota of periodontal pockets with different depths in therapy-resistant periodontitis. | this study presents the composition of the cultivable microbiota colonising periodontal pockets of different depths among 2 patient-groups classified as non-responsive (nr-group; 11 participants) or responsive (r-group; 10 participants) to periodontal treatment. microbiological samples from three types of pocket (< 4 mm deep a-samples; 4-5 mm b-samples; > 5 mm c-samples) were analysed by cultural methods for putative periodontitis pathogens, microbial groups constituting > or = 5% of the total c ... | 1999 | 10100039 |
| microbiota of successful osseointegrated dental implants. | the long-term survival of dental implants depends, in part, on control of bacterial infection in the peri-implant region. periodontal pathogens colonized implants symptomatic through infection, whereas the microbiota of successful implants was similar to that of periodontal health. this study examined the impact on the peri-implant microbiota of crown restorations; implant type; length of time of loading; history of implant or periodontal infections; and whether implants replaced single or multi ... | 1999 | 10102550 |
| cloning of fiba, encoding an immunogenic subunit of the fibril-like surface structure of peptostreptococcus micros. | although we are currently unaware of its biological function, the fibril-like surface structure is a prominent characteristic of the rough (rg) genotype of the gram-positive periodontal pathogen peptostreptococcus micros. the smooth (sm) type of this species as well as the smooth variant of the rg type (rgsm) lack these structures on their surface. a fibril-specific serum, as determined by immunogold electron microscopy, was obtained through adsorption of a rabbit anti-rg type serum with excess ... | 1999 | 10198013 |
| coaggregation of candida dubliniensis with fusobacterium nucleatum. | the binding of microorganisms to each other and oral surfaces contributes to the progression of microbial infections in the oral cavity. candida dubliniensis, a newly characterized species, has been identified in human immunodeficiency virus-seropositive patients and other immunocompromised individuals. c. dubliniensis phenotypically resembles candida albicans in many respects yet can be identified and differentiated as a unique candida species by phenotypic and genetic profiles. the purpose of ... | 1999 | 10203506 |
| adherence of peptostreptococcus micros morphotypes to epithelial cells in vitro. | peptostreptococcus micros, which is associated with oral and non-oral mixed anaerobic infections, occurs in three colony morphotypes, the smooth type, the rough type and the smooth variant of the rough type. these types differ in surface structures; the rough type expresses large fibrillar surface appendages, which are absent on the surface of both the smooth and the smooth variant of the rough type. to determine the role of these surface structures in adherence we characterized the adherence of ... | 1999 | 10204480 |
| metronidazole susceptibility testing of anaerobic bacteria associated with periodontal disease. | the aim of the present investigation was to determine the susceptibility of prevotella intermedia, porphyromonas gingivalis, fusobacterium and peptostreptococcus micros to metronidazole in vitro. two methods were applied on each isolated strain: agar dilution and epsilometer etest. a total of fifty three wild test strains (13 p.intermedia, 14 p. gingivalis, 14 f.spp and 12 p.micros) were isolated from patients with periodontitis. the etest appears to be a simple, rapid and reliable method for th ... | 1999 | 10223399 |
| microbiological and clinical effects of a 1% chlorhexidine-gel in untreated periodontal pockets from adult periodontitis patients. | the aim of this study was to report the microbiological and clinical effects of repeated subgingival administration of a 1% chlorhexidine-gel in periodontal pockets from 10 patients with adult periodontitis. results showed that the experimental treatment significantly improved clinical parameters (plaque index, gingival bleeding index, and pocket probing depth). direct subgingival administration of chlorhexidine-gel also produced a remarkable modification in the proportions of putative periodont ... | 1999 | 10322610 |
| fungi in therapy-resistant apical periodontitis. | the occurrence of yeasts in 967 microbiological endodontic samples taken from root canals in persistent endodontic infections was studied. the sampling was done by general practitioners in various parts of finland from root canal infections which did not respond favourably to standard conservative therapy. the samples were cultivated aerobically on a non-selective enriched horse blood agar medium, on tsbv agar medium in 5% co2 and anaerobically on horse blood agar medium. micro-organisms were fo ... | 1997 | 10332243 |
| effects of hydrogen peroxide on growth and selected properties of porphyromonas gingivalis. | in this study we first evaluated the effects of hydrogen peroxide (h2o2) on growth and selected properties of porphyromonas gingivalis, and compared them with those obtained by a reducing agent (cysteine). the growth of p. gingivalis was only moderately affected when h2o2 was added at concentrations up to 30 mm in a complex culture medium. however, when a defined basal medium was used, h2o2 at a concentration of 3 mm completely inhibited growth of p. gingivalis. incorporation of cysteine at conc ... | 1999 | 10339828 |
| antibiotic susceptibility of putative periodontal pathogens in advanced periodontitis patients. | in the present study, the antibiotic susceptibility of most prevalent micro-organisms in advanced periodontitis patients was evaluated. in 56 patients, pooled subgingival plaque samples were taken from the deepest site of each quadrant and were cultivated anaerobically. from each patient, the 4 most frequently encountered types of bacterial colonies were subcultured and identified (rapid id 32 a). from all bacterial species identified in the 224 subcultures, the 4 most prevalent were used for su ... | 1999 | 10382573 |
| flow cytometry to monitor phagocytosis and oxidative burst of anaerobic periodontopathogenic bacteria by human polymorphonuclear leukocytes. | the reduced susceptibility to phagocytosis found among some periodontopathogenic anaerobes may account for the differences between invasive and non-invasive strains. we applied flow cytometry as a powerful tool to analyze and quantify phagocytosis using standardized cultures of oral anaerobes (porphyromonas gingivalis, prevotella intermedia, p. nigrescens, capnocytophaga gingivalis, c. ochracea, c. sputigena, fusobacterium nucleatum and peptostreptococcus micros) and heparinized whole blood. bac ... | 1999 | 10384401 |
| destructive knee joint infection caused by peptostreptococcus micros: importance of early microbiological diagnosis. | peptostreptococcus micros is a commensal of the oral cavity and the genitourinary tract that rarely causes serious infections. a case of a destructive knee joint infection with rapid progress caused by p. micros is presented. the significance of the microbiological findings was initially not acknowledged, which contributed to a nonsuccessful clinical outcome. | 1999 | 10405436 |
| clinical and microbiological effects of initial periodontal therapy in conjunction with amoxicillin and clavulanic acid in patients with adult periodontitis. a randomised double-blind, placebo-controlled study. | the aim of the present study was to investigate the clinical and microbiological effects of initial periodontal therapy in conjunction with systemic amoxicillin plus clavulanic acid in adult periodontitis patients using a double-blind, parallel-group, and placebo-controlled protocol. 21 patients with a clinical diagnosis of generalised adult periodontitis were recruited. clinical measurements and microbiological assessments were carried out at baseline, 3, and 12 months post-treatment. approxima ... | 1999 | 10412851 |
| periodontitis associated bacteria in supragingival plaque of dental hygienists: stability of carrier state and clinical development. | the purpose of this study was the clinical and microbiological re-examination of dental hygienists, who, 30 months before, had shown remarkably high supragingival levels of periodontitis-associated micro-organisms. interdental plaque was collected from the same molar sites and investigated by the same immunofluorescence assay with taxa-specific monoclonal antibodies as at the initial examination. on average, the 15 re-examined subjects showed slightly increased plaque levels but unchanged bleedi ... | 1999 | 10424388 |
| infection-stimulated infraosseus inflammation and bone destruction is increased in p-/e-selectin knockout mice. | infections of the dental pulp commonly result in infraosseus inflammation and bone destruction. however, the role of phagocytic leucocytes in the pathogenesis of pulpal infections has been uncertain. in this work we used p/e-/- selectin-deficient mice, which lack rolling adhesion of leucocytes to endothelium and mimic the human syndrome, leucocyte adhesion deficiency ii (lad-ii), to test the hypothesis that phagocytic leucocytes protect against pulpal infection and subsequent periapical infraoss ... | 1999 | 10447722 |
| in vitro activity of gemifloxacin (sb 265805) against anaerobes. | gemifloxacin mesylate (sb 265805), a new fluoronaphthyridone, was tested against 359 recent clinical anaerobic isolates by the national committee for clinical laboratory standards reference agar dilution method with supplemented brucella blood agar and an inoculum of 10(5) cfu/spot. comparative antimicrobials tested included trovafloxacin, levofloxacin, grepafloxacin, sparfloxacin, sitafloxacin (du-6859a), penicillin g, amoxicillin clavulanate, imipenem, cefoxitin, clindamycin, and metronidazole ... | 1999 | 10471570 |
| [clinical evaluation of anaerobic infections in patients with bronchopulmonary infections diagnosed by transtracheal aspiration]. | we evaluated the clinical and bacteriologic features in the patients with bronchopulmonary infections isolated anaerobes from transtracheal aspirates between april 1990 and march 1998. some anaerobe was isolated in 42 (10.9%) in 387 patients whom we performed transtracheal aspiration (tta), in 42 (15.7%) of 268 in whom some organism was isolated from tta, or in 42 (16.3%) of 257 patients in whom some bacterium excluding acid-fast bacteria, fungi or mycoplasma from tta. the isolation rate of anae ... | 1999 | 10481403 |
| microbiological features of papillon-lefèvre syndrome periodontitis. | papillon-lefevre syndrome patients exhibit hyperkeratosis palmo-plantaris and severe periodontitis. the syndrome is an autosomal recessive trait, but the mechanism of periodontal destruction is not known. this report presents the clinical and microbiological features of an 11-year old girl with papillon-lefèvre syndrome. clinical examination included conventional periodontal measurements and radiographic analysis. in samples from 3 deep periodontal lesions, the occurrence of major suspected peri ... | 1999 | 10487314 |
| tetracycline-coated polytetrafluoroethylene barrier membranes in the treatment of intraosseous periodontal lesions. | periodontal pathogens are detrimental to periodontal healing in barrier membrane-assisted periodontal therapy. tetracycline-coating of barrier membranes may reduce levels of infecting pathogens. this study evaluated the clinical and microbiological effects of tetracycline-coated expanded polytetrafluoroethylene (t-eptfe) barrier membranes in the treatment of 2- to 3-wall intraosseous periodontal lesions around mandibular molars. | 1999 | 10505803 |
| microbiological understandings and mysteries of noma (cancrum oris). | the microbiologic history of noma was reviewed. studies have associated the disease process with large numbers of fusiform bacilli and spirochetal organisms. in order to study the microbiology of the staging and infection periods of noma 62 nigerian children, aged 3-14 years, 22 children had acute necrotizing ulcerative gingivitis (anug) and were also malnourished, 20 exhibited no acute necrotizing ulcerative gingivitis but were malnourished and 20 were free of acute necrotizing ulcerative gingi ... | 1999 | 10522213 |
| beta-hemolytic streptococci and other beta-hemolytic organisms in apical periodontitis and severe marginal periodontitis. | thirteen teeth with necrotic pulps and apical periodontitis and nine severe periodontal pockets were cultured for presence of beta-hemolytic streptococci and other beta-hemolytic organisms. samples were dispersed and plated on two non-selective and one selective growth media and incubated anaerobically and in 10% co2 in air. a total of 59 beta-hemolytic colonies were purified and identified. eight beta-hemolytic streptococcal isolates were obtained from three of the severe marginal periodontitis ... | 1999 | 10530151 |
| activities of gemifloxacin (sb 265805, lb20304) compared to those of other oral antimicrobial agents against unusual anaerobes. | the activities of gemifloxacin (sb 265805, lb20304) and comparator agents were determined by an agar dilution method against 419 clinical strains of less-commonly identified species of anaerobes. gemifloxacin was generally more active than trovafloxacin against gram-positive strains by one to two dilutions. peptostreptococci (peptostreptococcus asaccharolyticus, peptostreptococcus magnus, peptostreptococcus micros, and peptostreptococcus prevotii) and porphyromonas spp. (porphyromonas asaccharol ... | 1999 | 10543754 |
| peptostreptococcus micros coaggregates with fusobacterium nucleatum and non-encapsulated porphyromonas gingivalis. | coaggregation is one of the potential colonization strategies of oral microorganisms, often involving fimbrial structures in the interactions. in this study, the coaggregation characteristics of the rough and smooth genotypes of the periodontal pathogen peptostreptococcus micros were compared to investigate the role of the fibril-like structures of the rough genotype in coaggregation. of the 11 oral species tested, only fusobacterium nucleatum strains and non-encapsulated porphyromonas gingivali ... | 2000 | 10612731 |
| lack of antimicrobial effect on periodontopathic bacteria by ultrasonic and sonic scalers in vitro. | the purpose of this study was to assess the antimicrobial effects of a sonic and ultrasonic scaler generally used for subgingival scaling on gram-negative and gram-positive periodontopathic bacteria. | 2000 | 10703657 |
| peptostreptococcus micros smooth and rough genotypes in periodontitis and gingivitis. | two genotypes can be distinguished within the species peptostreptococcus micros: a smooth (sm) and a rough (rg) type. to date no systematic study has been performed on the prevalence and proportion of both types in untreated periodontitis patients and subjects without destructive periodontal disease. therefore, the present study was performed to investigate: 1) the relative importance of the sm and the rg genotype of p micros in periodontitis and gingivitis; 2) the correlation between smoking an ... | 2000 | 10711611 |
| a case of paraspinal abscess and diskitis due to peptostreptococcus micros. | 2000 | 10722468 | |
| early microbial colonization of permucosal implants in edentulous patients. | in edentulous patients, the microbial colonization of permucosal implants of sintered hydroxyapatite was studied. samples were taken from mucosa and dentures before insertion of implants and from supra- and subgingival sites two to 10 weeks after insertion. in total, five patients and 10 implants with clinically healthy peri-implant tissues were studied. the samples were investigated by dark-field microscopy and anaerobic culture. the supragingival plaque of the implants was dominated by gram-po ... | 1987 | 10872401 |
| the periodontal abscess (i). clinical and microbiological findings. | little information is available regarding the diagnosis and microbiology of periodontal abscesses. the aim of this descriptive clinical and microbiological study was to provide more information in order to help in the characterisation of the periodontal abscess associated to periodontitis. | 2000 | 10883867 |
| proteolysis and utilization of albumin by enrichment cultures of subgingival microbiota. | subgingival dental plaque consists mainly of microorganisms that derive their energy from amino acid fermentation. their nutrient requirements are met by the subgingival proteolytic system, which includes proteases from microorganism and inflammatory cells, and substrate proteins from sulcus exudate, including albumin. to determine the selective effect of individual proteins on microbiota, we used albumin as the main substrate for growth. eight subgingval plaque samples from untreated periodonta ... | 1999 | 10895689 |
| toll-like receptor 4-deficient mice have reduced bone destruction following mixed anaerobic infection. | c3h/hej mice have an impaired ability to respond to lipopolysaccharide (lps) due to a mutation in the gene that encodes toll-like receptor 4 (tlr4). the effect of tlr4 deficiency on host responses to endodontic infections is unknown. in the present study, we compared periapical bone destruction, sepsis, and inflammatory cytokine production in lps-hyporesponsive c3h/hej and wild-type control c3h/heouj mice. the mandibular first molars of both strains were subjected to pulpal exposure and infectio ... | 2000 | 10899873 |
| characterization of bacterial orofacial infections using a new murine model. | we devised a new murine orofacial infection model using bacteria from odontogenic infection origins and characterized the experimental infections. in this model, bacteria were injected into the submandible of mice. streptococcus constellatus and peptostreptococcus micros produced a single abscess at the injection site and their abscess-forming and lethal abilities were low: the median abscess-forming dose (af(50)) of s. constellatus and p. micros were 10(8.5-10.7)and 10(10.2-10.6)cfu/mouse, and ... | 2000 | 10906266 |
| "checkerboard" assessments of periodontal microbiota and serum antibody responses: a case-control study. | we explored the association between subgingival microbial profiles and serum igg responses to periodontal microbiota in relation to clinical periodontal status. | 2000 | 10914791 |
| b-cell deficiency predisposes mice to disseminating anaerobic infections: protection by passive antibody transfer. | we have previously demonstrated that a high proportion of rag-2 scid knockout mice, which lack t and b cells, develop orofacial abscesses and disseminated infections following pulpal infection, whereas immunocompetent control mice do not. in the present study, we sought to identify the components of the adaptive immune response which contribute to protection against disseminating anaerobic infections and sepsis. for this purpose, various genetically engineered immunodeficient mice were employed, ... | 2000 | 10992465 |
| detection of major putative periodontopathogens in korean advanced adult periodontitis patients using a nucleic acid-based approach. | although extensive microbial analyses have been performed from subgingival plaque samples of periodontitis patients, systematic analysis of subgingival microbiota has not been carried out in a korean population so far. the purpose of this study was to describe the prevalence of major putative periodontopathogens in korean patients by culture-independent methods. | 2000 | 11022767 |
| differences in the composition of the subgingival microbiota of two periodontitis populations of different geographical origin. a comparison between spain and the netherlands. | the purpose of this study was to compare the subgingival microbiota of two geographically distinct patient populations using identical clinical and bacteriological methods. adult patients with a diagnosis of periodontitis were consecutively selected according to pre-defined clinical criteria. microbiological samples were taken from the deepest four sites with bleeding. the samples were plated on blood agar plates, for the determination of the total anaerobic counts and identification of specific ... | 2000 | 11037754 |
| bacterial susceptibility to amoxicillin and potassium clavulanate in advanced periodontitis patients not responding to mechanical therapy. | between 4 and 8% of periodontitis patients are reported to respond poorly to conventional therapy. in these cases, adjunctive use of systemic antibiotics might be a reasonable therapeutic approach. the purpose of this study was to evaluate the effects of systemic amoxicillin/clavulanate as adjunct to periodontal surgery on the predominant subgingival microorganisms in patients not responding to mechanical therapy. furthermore, the bacterial susceptibility to amoxicillin/clavulanate was analyzed ... | 2000 | 11073328 |
| bacteriology of histopathologically defined appendicitis in children. | acute appendicitis is the most common surgical emergency in childhood. however, the pathogenesis and detailed microbiology are obscure. | 2000 | 11099090 |
| profile of subgingival microbiota in children with mixed dentition. | a diversity of microbial species has been detected in children's oral flora at an early age. to investigate the composition of the subgingival microbiota of different groups of teeth in children with mixed dentition, 40 systemically healthy children, aged 7-8 years, randomly chosen, were examined. subgingival plaque samples were taken from the mesiobuccal sites of 21, 41, 16 and 36 permanent teeth and 53, 73, 64 and 84 deciduous teeth. the samples were cultured for bacterial isolation anaerobica ... | 2000 | 11155173 |
| interleukin-6 deficiency increases inflammatory bone destruction. | periapical bone destruction occurs as a consequence of pulpal infection. in previous studies, we showed that interleukin-1 (il-1) is the primary stimulator of bone destruction in this model. il-6 is a pleiotropic cytokine that is induced in these infections and has both pro- and anti-inflammatory activities. in the present study, we determined the role of il-6 in regulating il-1 expression and bone resorption. the first molars of il-6 knockouts (il-6(-/-)) and wild-type mice were subjected to su ... | 2001 | 11159963 |
| early colonization of dental implants by putative periodontal pathogens in partially edentulous patients. | there is limited scientific information available on the early colonization of the peri-implant pockets in partially edentulous individuals. knowledge about this process is one step in better understanding the etiology and pathogenesis of peri-implantitis. in this study, the early colonization of the peri-implant pockets by putative periodontal pathogens was studied in 20 partially edentulous individuals using anaerobic culture techniques. at baseline, the presence and levels of putative periodo ... | 2000 | 11168244 |
| growth inhibitory activity of gutta-percha points containing root canal medications on common endodontic bacterial pathogens as determined by an optimized quantitative in vitro assay. | gutta-percha points containing calcium hydroxide, zinc oxide (zno), a mixture of zno and chlorhexidine (zno/chx), iodine-polyvinylpyrrolidone (zno/j-pvp), or a mixture of chx and j-pvp and zno (zno/chx/j-pvp) were tested for their ability to inhibit growth of pure cultures of bacterial species commonly involved in endodontic infections (peptostreptococcus micros, streptococcus intermedius, enterococcus faecalis, and porphyromonas gingivalis). to quantitate growth inhibition, an in vitro assay wa ... | 2000 | 11199764 |
| molecular epidemiology and association of putative pathogens in root canal infection. | the purpose of this study was to investigate the epidemiology of putative pathogens in root canals with apical periodontitis and to determine the associations among the putative pathogens. eighteen symptomatic and 20 asymptomatic teeth from 36 subjects were studied. this research was performed with polymerase chain reaction and hybridization using rrna-based oligonucleotide probes. the most frequently found species was fusobacterium sp. (68.4%), followed by peptostreptococcus micros (44.7%) and ... | 2000 | 11199802 |
| detection of peptostreptococcus micros dna in clinical samples by pcr. | peptostreptococcus micros is a gram-positive anaerobic coccus which, although considered to be a natural commensal of the human oral cavity, is associated with periodontal, endodontal and peritonsillar infections. identification of the organism has to date relied upon conventional culture methods and biochemical analyses. the purpose of this study was to develop a pcr method for rapid and specific identification of this organism in clinical samples. a pair of primers was selected, each of which ... | 2001 | 11232771 |
| comparison of microbial composition in the subgingival plaque of adult crowded versus non-crowded dental regions. | it has been reported in the literature that certain species of bacteria (periodontopathogens) present in the subgingival plaque are associated with destructive periodontal disease. the purpose of this study was to investigate and compare the presence and proportional distribution of periodontopathogens in the subgingival plaque of adult crowded versus non-crowded dental regions. thirty adult patients with anterior dental crowding were selected from the orthodontic clinic of the university of pen ... | 2000 | 11307190 |
| amoxicillin plus metronidazole in the treatment of adult periodontitis patients. a double-blind placebo-controlled study. | the aim of this double-blind, parallel study was to evaluate the adjunctive effects of systemically administered amoxicillin and metronidazole in a group of adult periodontitis patients who also received supra- and subgingival debridement. | 2001 | 11314884 |
| recovery of anaerobic bacteria from 3 patients with infection at a pierced body site. | we describe 3 adolescents who developed infections due to anaerobes at pierced body sites: the nipple, the umbilicus, and the nasal septum. anaerobes (prevotella intermedia and peptostreptococcus anaerobius) were recovered from pure culture of specimens obtained from 1 patient with nipple infection and were mixed with aerobic bacteria in cultures of specimens obtained from 2 patients (streptococcus aureus, peptostreptococcus micros, and prevotella melaninogenica were recovered from a patient wit ... | 2001 | 11389513 |
| smoking affects the subgingival microflora in periodontitis. | tobacco smoking has been identified as one major risk factor for destructive periodontal disease. scaling and root planing have been shown to be less effective in smokers with periodontitis. the aim of the present study was to compare the subgingival microbial flora of treated and untreated smokers and non-smokers. | 2001 | 11394403 |
| [pharmacological and pharmacokinetic properties of azithromycin (zithromac), a novel 15-membered ring macrolide antibacterial agent]. | azithromycin (zithromac), a 15-membered ring macrolide antibacterial agent, was approved to be manufactured in japan in march 2000. it showed good in vitro and/or in vivo antibacterial activities against staphylococcus aureus, streptococcus pneumoniae, streptococcus pyogenes, peptostreptococcus micros, haemophilus influenzae, moraxella catarrhalis, mycoplasma pneumoniae and chlamydia pneumoniae. its activity against h. influenzae was particularly more potent than that of currently used macrolide ... | 2001 | 11411344 |
| microbiological characteristics of subgingival microbiota in adult periodontitis, localized juvenile periodontitis and rapidly progressive periodontitis subjects. | to describe the prevalence of the cultivable subgingival microbiota in periodontal diseases and to draw attention to the polymicrobial nature of periodontic infections. | 2001 | 11422244 |
| an in vitro evaluation of the antimicrobial efficacy of irrigants on biofilms of root canal isolates. | the bactericidal effect of four antimicrobial agents was investigated against single-species biofilms derived from a range of root canal isolates. | 2001 | 11482142 |
| antibacterial properties of electron beam-sterilized gutta-percha cones. | the purpose of the study was to determine the effect of electron beam sterilization on gutta-percha cones (gpcs) at different times after sterilization. an agar diffusion test was used with -one aerobic bacterium (bacillus subtilis) and five oral anaerobic bacteria (fusobacterium nucleatum, peptostreptococcus micros, porphyromonas gingivalis, propionibacterium acnes, and veillonella parvula). with each microorganism 30 agar plates were prepared, evenly distributed among three groups (group 1: un ... | 2001 | 11487145 |
| molecular analysis of peptostreptococcus micros isolates from patients with periodontitis. | recent studies provide strong evidence implicating peptostreptococcus micros in the pathogenesis of various oral infections, including oropharyngeal abscesses and periodontal disease. to date, very little is known regarding the role of p. micros in periodontal disease. therefore, a genetic analysis was initiated to differentiate among strains of p. micros infecting periodontal patients. | 2001 | 11495135 |
| efficacy of manual and powered toothbrushes (ii). effect on microbiological parameters. | the purpose of the present investigation was to determine the effect of self-performed supragingival plaque removal using either manual (crest complete) or power (braun 3d plaque remover) toothbrushing on supra and subgingival plaque composition. | 2001 | 11686813 |
| absence of a specific subgingival microflora in adults with down's syndrome. | periodontal disease in down's syndrome (ds) is generally characterized by a high degree of bone loss. bone loss of 5 mm or more is observed in 70% of these subjects. among ds subjects, considerable differences in disease progression occur. so far, no studies have been conducted in which specific properties of the subgingival microflora have been related to the condition observed. | 2001 | 11686820 |
| association of early onset periodontitis microbiota with aspartate aminotransferase activity in gingival crevicular fluid. | the objective of this study was to determine the relationship between the activity of the enzyme aspartate aminotransferase (ast) in gingival crevicular fluid (gcf) using the colorimetric periogard (ptm) test and the subgingival microflora in early onset periodontitis lesions. | 2001 | 11737506 |
| aggressive periodontitis associated with fanconi's anemia. a case report. | fanconi's anemia is an autosomal recessive disease associated with chromosomal breakage as well as pancytopenia, skin pigmentation, renal hypoplasia, cardiac defects, microcephaly, congenital malformations of the skeleton, hypogonadism, and increased risk of leukemia. the present report describes the periodontal clinical and microbiological status of an 11-year old male having fanconi's anemia. | 2001 | 11759873 |
| [a comparative study of various evaluation methods of the antibiotic sensitivity of strict anaerobic bacteria of the subgingival flora]. | the study on the sensitiveness of slow-growing anaerobes bacteria to antibiotics is delicate when you consider the technical motives that make it difficult to transpose the standard methods frequently used in microbiological laboratories. the three main methods used to determine susceptibility to antibiotics are: disk-diffusion test, antibiotics containing microdilution plates and atb ana (biomérieux). the aim of this study is to compare the effectiveness of each of these methods on severe anaer ... | 2001 | 11808376 |
| antimicrobial effects of 2.94 microm er:yag laser radiation on root surfaces: an in vitro study. | this in vitro study investigated the antimicrobial effects of 2.94 microm er:yag laser radiation on root surfaces. | 2002 | 11846852 |
| effects of instrumentation, irrigation and dressing with calcium hydroxide on infection in pulpless teeth with periapical bone lesions. | the aim of this study was to evaluate the fate of microorganisms in root canals of teeth with infected pulps and periapical bone lesions with and without the use of calcium hydroxide medication. | 2002 | 11858203 |
| in vitro activity of gemifloxacin compared to seven other oral antimicrobial agents against aerobic and anaerobic pathogens isolated from antral sinus puncture specimens from patients with sinusitis. | using a microbroth method for aerobes and agar dilution for anaerobes, we studied the comparative in vitro activity of gemifloxacin, three fluoroquinolones, two macrolides and two beta-lactams, against 207 aerobic and 162 anaerobic antral sinus puncture isolates. gemifloxacin was active at < or = 0.25 ug/ml against 198/207 [96%] aerobes and 127/162 [78%] anaerobes or 325/369 [88%] of all isolates and was the most active quinolone on a weight basis against gram-positive organisms. all haemophilus ... | 2002 | 11858906 |
| periodontal bacteria in rabbit mandibular and maxillary abscesses. | despite the high incidence of odontogenic abscesses in pet rabbits, published data on the bacteriology of these infections are lacking, and clinical cultures are often ambiguous, making antibiotic choices difficult. in order to define the bacteriology of these infections, 12 rabbit mandibular and maxillary abscesses were cultured aerobically and anaerobically. all specimens yielded pathogenic bacteria, including fusobacterium nucleatum, prevotella heparinolytica, prevotella spp., peptostreptococ ... | 2002 | 11880435 |
| maternal periodontitis and prematurity. part ii: maternal infection and fetal exposure. | clinical data from the first 812 deliveries from a cohort study of pregnant mothers entitled oral conditions and pregnancy (ocap) demonstrate that both antepartum maternal periodontal disease and incidence/progression of periodontal disease are associated with preterm birth and growth restriction after adjusting for traditional obstetric risk factors. in the current study we present measures of maternal periodontal infection using whole chromosomal dna probes to identify 15 periodontal organisms ... | 2001 | 11887461 |
| subgingival microbiota of indigenous indians of central america. | to define the subgingival microbial profiles of adult subjects from a previously identified rural community of indigenous indians in guatemala, central america. | 2002 | 11895544 |
| bacteriology and antimicrobial susceptibility of gram-positive cocci isolated from pus specimens of orofacial odontogenic infections. | we recently reported the beta-lactamase production and antimicrobial susceptibility of anaerobic gram-negative rods isolated from pus specimens of 93 orofacial odontogenic infections. in this report, we determine the bacteriology and antimicrobial susceptibility of bacteria other than anaerobic gram-negative rods, mainly gram-positive cocci, isolated from the same specimens. streptococcus constellatus and peptostreptococcus micros were frequent isolates from all types of infection examined. pept ... | 2002 | 11929563 |
| treatment of papillon-lefèvre syndrome periodontitis. | conventional mechanical treatment of papillon-lefèvre syndrome periodontitis has a poor prognosis. this report describes an effective antimicrobial treatment of rapidly progressing periodontitis in an 11-year old girl having papillon-lefèvre syndrome. | 2002 | 11966936 |
| quantitative microbiological study of human carious dentine by culture and real-time pcr: association of anaerobes with histopathological changes in chronic pulpitis. | the bacteria found in carious dentine were correlated with the tissue response of the dental pulps of 65 teeth extracted from patients with advanced caries and pulpitis. standardized homogenates of carious dentine were plated onto selective and nonselective media under anaerobic and microaerophilic conditions. in addition, real-time pcr was used to quantify the recovery of anaerobic bacteria. primers and fluorogenic probes were designed to detect the total anaerobic microbial load, the genera pr ... | 2002 | 11980945 |
| parotid salivary s-iga antibodies during experimental gingivitis in smokers and non-smokers. | persons who smoke display a less pronounced increase of gingival bleeding in the experimental gingivitis model as compared with non-smokers. the aim of the present study was to investigate whether this could partly be explained by differences in levels of parotid total secretory iga (s-iga) or parotid s-iga reactive with selected oral microorganisms. parotid saliva samples were obtained from 11 smoking and 14 non-smoking volunteers, at baseline, after 5 and 14 days of full mouth experimental gin ... | 2002 | 12009188 |
| invasion of dentinal tubules by oral bacteria. | bacterial invasion of dentinal tubules commonly occurs when dentin is exposed following a breach in the integrity of the overlying enamel or cementum. bacterial products diffuse through the dentinal tubule toward the pulp and evoke inflammatory changes in the pulpo-dentin complex. these may eliminate the bacterial insult and block the route of infection. unchecked, invasion results in pulpitis and pulp necrosis, infection of the root canal system, and periapical disease. while several hundred ba ... | 2002 | 12097359 |
| combinations of bacterial species in endodontic infections. | this study was undertaken to investigate combinations of bacteria found in root-canal infections of teeth with periapical bone destruction without clinical signs and symptoms. | 2002 | 12196223 |
| genotypic diversity of clinical actinomyces species: phenotype, source, and disease correlation among genospecies. | we determined the frequency distribution of actinomyces spp. recovered in a routine clinical laboratory and investigated the clinical significance of accurate identification to the species level. we identified 92 clinical strains of actinomyces, including 13 strains in the related arcanobacterium-actinobaculum taxon, by 16s rrna gene sequence analysis and recorded their biotypes, sources, and disease associations. the clinical isolates clustered into 21 genogroups. twelve genogroups (74 strains) ... | 2002 | 12202591 |
| initial effect of controlled release chlorhexidine on subgingival microorganisms. | little or no data exist on the ability of subgingival application of periochip (2.5 mg chlorhexidine gluconate in a biodegradable chip; astra pharmaceuticals, westborough, ma, usa) to suppress periodontopathic microorganisms. the present study compared the subgingival microbiota of periodontitis sites receiving the chlorhexidine chip plus scaling and root planing (sc/rp) or sc/rp alone. | 2002 | 12366861 |
| recovery of anaerobic bacteria from a glossal abscess in an adolescent. | glossal abscess is infrequent in children. anaerobic bacteria are rarely recovered from this infection and never have been reported in children or adolescents. a 15-year-old patient presented with a tongue abscess following trauma. aspirate of the abscess yielded polymicrobial anaerobic flora: prevotella melaninogenica, fusobacterium nucleatum, and peptostreptococcus micros. the patient recovered following incision and drainage and 14 days of antimicrobial therapy with clindamycin. this report i ... | 2002 | 12395007 |
| two-part implants inserted in a one-stage or a two-stage procedure. a prospective comparative study. | the aim of this study was to evaluate the feasibility of using a two-part implant system in a one-stage procedure and to monitor the microflora in the peri-implant area in relation to clinical and radiographic outcome. | 2002 | 12445222 |
| heterogeneity within the gram-positive anaerobic cocci demonstrated by analysis of 16s-23s intergenic ribosomal rna polymorphisms. | peptostreptococci are gram-positive, strictly anaerobic bacteria which, although regarded as members of the commensal human microflora, are also frequently isolated from sites of clinical infection. the study of this diverse group of opportunist pathogens has been hindered by an inadequate taxonomy and the lack of a valid identification scheme. recent re-classification of the peptostreptococcus family into five distinct genus groups has helped to clarify the situation. however, this has been on ... | 2002 | 12448679 |
| comparison of 16s rdna-based pcr and checkerboard dna-dna hybridisation for detection of selected endodontic pathogens. | molecular methods have been used recently to investigate the bacteria encountered in human endodontic infections. the aim of the present study was to compare the ability of a 16s rdna-based pcr assay and checkerboard dna-dna hybridisation in detecting actinobacillus actinomycetemcomitans, bacteroides forsythus, peptostreptococcus micros, porphyromonas endodontalis, por. gingivalis and treponema denticola directly from clinical samples. specimens were obtained from 50 cases of endodontic infectio ... | 2002 | 12466407 |
| porphyromonas gingivalis, bacteroides forsythus and other putative periodontal pathogens in subjects with and without periodontal destruction. | bacteria play an essential role in the pathogenesis of destructive periodontal disease. it has been suggested that not all bacteria associated with periodontitis may be normal inhabitants of a periodontally healthy dentition. in particular, porphyromonas gingivalis and actinobacillus actinomycetemcomitans have been isolated infrequently from subjects without periodontitis. the aim of the present study was to compare prevalence and proportions of a number of periodontal bacteria in periodontitis ... | 2002 | 12472995 |
| dna from periodontopathogenic bacteria is immunostimulatory for mouse and human immune cells. | although bacterial dna (bdna) containing unmethylated cpg motifs stimulates innate immune cells through toll-like receptor 9 (tlr-9), its precise role in the pathophysiology of diseases is still equivocal. here we examined the immunostimulatory effects of dna extracted from periodontopathogenic bacteria. a major role in the etiology of periodontal diseases has been attributed to actinobacillus actinomycetemcomitans, porphyromonas gingivalis, and peptostreptococcus micros. we therefore isolated d ... | 2003 | 12540566 |
| the microflora recovered from the outer-surfaces of the frialit-2 implanto-prosthetic connector. | the aim of the present investigation was to examine the outer-surface microbiota of the prosthetic connector of frialit-2 implants, and to compare the microbial findings with the peri-implant parameters 2 years after functional loading. in 16 implant-treated patients (55.8 +/- 9.5 years) the outer-surface micro-organisms of the prosthetic connectors were determined in 32 frialit-2 implants. the functional loading time of the prosthetic suprastructures was 24.1 +/- 13.8 months on average. after r ... | 2003 | 12562362 |
| peptostreptococcus micros in primary endodontic infections as detected by 16s rdna-based polymerase chain reaction. | a 16s rdna-based polymerase chain reaction (pcr) method was used to detect peptostreptococcus micros in primary root canal infections. samples were collected from 50 teeth having carious lesions, necrotic pulps, and different forms of periradicular diseases. dna extracted from the samples was amplified using the pcr assay, which yielded a specific fragment of p. micros 16s rdna. p. micros was detected in 6 of 22 root canals associated with asymptomatic chronic periradicular lesions (27.3%), 2 of ... | 2003 | 12597709 |
| bactericidal activities of methoxyfluoroquinolones gatifloxacin and moxifloxacin against aerobic and anaerobic respiratory pathogens in serum. | gatifloxacin (bristol-myers squibb) and moxifloxacin (bayer) are new methoxyfluoroquinolones with broad-spectrum activity against aerobic and anaerobic pathogens of the respiratory tract. in this investigation, we analyzed the bactericidal activity in serum over time of these antimicrobials against three aerobic (streptococcus pneumoniae, haemophilus influenzae, and staphylococcus aureus) and four anaerobic (peptostreptococcus micros, peptostreptococcus magnus, fusobacterium nucleatum, and prevo ... | 2003 | 12654663 |
| an immunohistological study of the localization of bacteria invading root pulpal walls of teeth with periapical lesions. | we immunohistologically examined the prevalence and localization of bacteria invading dentinal tubules of the roots of teeth with infected canals. forty extracted teeth with apical lesions were selected and divided into two groups: a group of untreated teeth and a group of canal-enlarged teeth. the bacteria in the specimens were detected by brown-brenn stain and the labeled-streptavidin-biotin method with specific antisera for 16-bacteria. seventy percent of the examined teeth showed bacteria in ... | 2003 | 12669880 |
| differences in antimicrobial activity of four commercial 0.12% chlorhexidine mouthrinse formulations: an in vitro contact test and salivary bacterial counts study. | to evaluate the in vitro and in vivo antimicrobial activity of four commercial 0.12% chlorhexidine mouthrinses. | 2003 | 12694428 |