Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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| scrotal circumference and its relationship with testicular growth, age, and body weight in tho tho (bos indicus) bulls. | the present study was undertaken to assess the relationship between the scrotal circumference and testicular parameters with body weight and age in tho tho bulls (bos indicus), which were maintained at around the villages of national research centre on mithun (icar), jharnapani, nagaland, india. a total of 32 tho tho bulls were selected and divided into four groups according to their age and each group consisted of 8 bulls, namely, group i: 18-24 months (n = 8), group ii: 25-36 months (n = 8), g ... | 2014 | 27351012 |
| nacl-, protease-tolerant and cold-active endoglucanase from paenibacillus sp. yd236 isolated from the feces of bos frontalis. | bos frontalis, which consumes bamboo and weeds, may have evolved unique gastrointestinal microorganisms that digest cellulase. a paenibacillus sp. yd236 strain was isolated from b. frontalis feces, from which a gh8 endoglucanase gene, pglue8 (1107 bp, 54.5 % gc content), encoding a 368-residue polypeptide (pglue8, 40.4 kda) was cloned. pglue8 efficiently hydrolyzed barley-β-d-glucan followed by cmc-na, soluble starch, laminarin, and glucan from black yeast optimally at ph 5.5 and 50 °c, and reta ... | 2016 | 27376014 |
| pimply gut condition in mithun (bos frontalis) calves. | the present observation was recorded at national research centre on mithun, jharnapani from may 2010 to september 2012. a total of 15 mithun calves, which died in and around jharnapani, were attended and detailed post-mortem examination was carried out. out of these, five calves (33.33 %) aging between 1 and 1.5 years exhibiting the condition of chronic wasting and diarrhoea were found positive for pimply gut condition based on gross and microscopic examination. post-mortem examination revealed ... | 2016 | 27413288 |
| effects of low-density lipoproteins as additive on quality parameters and oxidative stress following cryopreservation of mithun (bos frontalis) spermatozoa. | artificial breeding of mithun poses several challenges including lack of standard protocol for cryopreservation of spermatozoa. this is further complicated by harmful effects of hen's egg yolk (ey) as additive in extender. purified low-density lipoproteins (ldl) extracted from ey have been shown as beneficial over ey extender for long-term semen storage in several species. this investigation explored use of ldl versus ey on semen quality and oxidative stress following freezing-thawing of spermat ... | 2016 | 27418332 |
| status of tick infections among semi-wild cattle in arunachal pradesh, india. | to explore the seasonal prevalence of tick infections in mithun (bos frontalis) and yak (b. grunniens) a study was conducted in papum pare district, kurung-kumey district and west kameng district of arunachal pradesh, india from december 2012 to november 2014. adult ticks were collected from both the animals during the month of december 2012 to november 2014. ectoparasites were identified on the basis of their morpho-anatomical features observed through light microscope. a total of nine differen ... | 2017 | 27614479 |
| sequence based structural characterization and genetic diversity analysis of full length tlr4 cds in crossbred and indigenous cattle. | the exploration of candidate genes for immune response in cattle may be vital for improving our understanding regarding the species specific response to pathogens. toll-like receptor 4 (tlr4) is mostly involved in protection against the deleterious effects of gram negative pathogens. approximately 2.6 kb long cdna sequence of tlr4 gene covering the entire coding region was characterized in two indian milk cattle (vrindavani and tharparkar). the phylogenetic analysis confirmed that the bovine tlr ... | 2017 | 27715456 |
| evolutionary dynamics of meiotic recombination hotspots regulator prdm9 in bovids. | hybrid sterility or reproductive isolation in mammals has been attributed to allelic incompatibilities in a dna-binding protein prdm9. not only is prdm9 exceptional in being the only known 'speciation gene' in vertebrates, but it is also considered to be the fastest evolving gene in the genome. the terminal zinc finger (zf) domain of prdm9 specifies genome-wide meiotic recombination hotspot locations in mammals. intriguingly, prdm9 zf domain is highly variable between as well as within species, ... | 2017 | 27744561 |
| report of amblyomma testudinarium in mithuns (bos frontalis) from eastern mizoram (india). | physical examination of semi-domesticated, free ranging mithuns (bos frontalis) during an animal health check-up and treatment camp organized at khuwangleng village in the champhai district of mizoram, india and adjacent to myanmar border revealed presence of unusually large blood engorged ticks attaching to the dewlap and inner aspects of thighs. on the basis of morphological study, the ticks were found indistinguishable from female amblyomma testudinarium. prevalence rate of the tick species i ... | 2016 | 27876918 |
| animal fascioliasis: perspectives from high altitudinal regions. | the parasitic flukes of the genus fasciola (platyhelminthes: trematoda: digenea) cause fascioliasis or liver-rot disease in ruminant livestock in tropical and sub-tropical regions of the world. classically, two species of fasciola- f. hepatica and f. gigantica, are universally recognized as taxonomically valid species. our survey studies on ovid and bovid animals including yak and mithun from high altitudinal mountainous regions in northeast india revealed the occurrence of fasciola gigantica an ... | 2016 | 27890078 |
| prioritizing fodder species based on traditional knowledge: a case study of mithun (bos frontalis) in dulongjiang area, yunnan province, southwest china. | livestock rearing is one of the oldest and most important types of smallholder farming worldwide. the sustainability of livestock production depends on the efficient utilization of locally available resources. some traditional methods of raising livestock may offer valuable lessons in this regard. this study documented and evaluated local knowledge of wild forage plants in the dulongjiang area in southwest china in the context of rearing mithun (bos frontalis) in order to provide a sound evidenc ... | 2017 | 28472968 |
| first report on serological evidence of bovine viral diarrhea virus (bvdv) infection in farmed and free ranging mithuns (bos frontalis). | despite reports of bvdv infection in several domestic and wild ruminants, no information exists for mithun (bos frontalis) species. hence, this study was undertaken to determine prevalence of bvdv infection in mithuns, which contribute significantly to local economy in the north eastern region of india. blood and serum samples were collected between 2013 and 2016 from mithuns (n = 466) belonging to the states of nagaland, mizoram, and arunachal pradesh. serum samples were tested for bvdv antibod ... | 2017 | 28504301 |
| effect of season and age on scrotal circumference, testicular parameters and endocrinological profiles in mithun bulls. | mithun is a domesticated free-range bovine species primarily used as a meat animal and is a pride of north eastern hilly regions of india. the present study was conducted to measure the effect of seasons on scrotal & testicular biometrics and endocrinological profiles for different age groups at different seasons in mithun bulls. a total of 30 mithun males were selected from the mithun breeding farm, icar-nrc on mithun, medziphema, nagaland, india and were equally distributed into five groups ba ... | 2017 | 28601151 |
| isolation, identification and retrospective study of foot-and-mouth disease virus from affected mithun (bos frontalis) in north-eastern india. | foot-and-mouth disease (fmd) is a contagious disease of cloven-hoofed animals that causes substantial and perpetual economic loss. apart from the contagious nature of the disease, the fmd virus can establish in a "carrier state" among all cloven-hoofed animals. the mithun (bos frontalis), popularly called the "cattle of mountain," is found in the geographically isolated, hilly region of north-east india: arunachal pradesh, nagaland, manipur and mizoram. despite the geographical inaccessibility, ... | 2017 | 28707820 |
| molecular identification of mecistocirrus digitatus and toxocara vitulorum in the mithun (bos frontalis) from north-east india. | mecistocirrus digitatus and toxocara vitulorum are common pathogenic nematode parasites of mithun (bos frontalis). species identification by morphological features was confirmed by molecular identification of m. digitatus and t. vitulorum. the internal transcribed spacer-2 (its-2) region and beta tubulin gene of m. digitatus were polymerase chain reaction (pcr) amplified and sequenced. its-2 sequence analysis showed 100% homology with other isolates of m. digitatus and 83% identity with haemonch ... | 2017 | 28848270 |
| draft genome of the gayal, bos frontalis. | gayal (bos frontalis), also known as mithan or mithun, is a large endangered semi-domesticated bovine that has a limited geographical distribution in the hill-forests of china, northeast india, bangladesh, myanmar, and bhutan. many questions about the gayal such as its origin, population history, and genetic basis of local adaptation remain largely unresolved. de novo sequencing and assembly of the whole gayal genome provides an opportunity to address these issues. we report a high-depth sequenc ... | 2017 | 29048483 |
| pathological studies on helminth parasitic infection in mithun (bos frontalis). | a pathological study was carried out in different helminth parasite infection organs in 110 animals during the period from 2010 to 2016. histopathological examination of hydatid cysts in the liver, showed extensive fibrous connective tissue proliferation with eosinophilic and lymphocytic infiltration, in lung, parenchyma showed severe emphysema with infiltration of alveolar macrophages and lymphocytes infiltration. in toxocara infection, polymorphonuclear infiltration in the sub-mucosa with hype ... | 2017 | 29114121 |
| species composition and environmental adaptation of indigenous chinese cattle. | indigenous chinese cattle combine taurine and indicine origins and occupy a broad range of different environments. by 50 k snp genotyping we found a discontinuous distribution of taurine and indicine cattle ancestries with extremes of less than 10% indicine cattle in the north and more than 90% in the far south and southwest china. model-based clustering and f4-statistics indicate introgression of both banteng and gayal into southern chinese cattle while the sporadic yak influence in cattle in o ... | 2017 | 29170422 |
| gene cloning and expression of fungal lignocellulolytic enzymes from the rumen of gayal (bos frontalis). | a total of 6,219 positive clones were obtained by constructing a bac library of uncultured ruminal fungi of gayal, and two clones (xynf1 and eglf2) with lignocellulolytic enzyme activity were selected. the sequencing results showed that xynf1 and eglf2 had 903-bp, and 1,995-bp, open reading frames likely to encode β-xylanase (xynf1) and β-glucosidase (eglf2), respectively. the amino acid sequence of xynf1 had 99% coverage and 95% homology to the endo-β-1,4-xylanase encoded by the cellulase gene ... | 2017 | 29225283 |
| isolation and characterization of the major histocompatibility complex dqa1 and dqa2 genes in gayal (bos frontalis). | the species origin of yunnan gayal has been controversial since many years. however, few recent genetic studies have suggested that it has perhaps originated from the hybridization between male bos frontalis and female b. taurus or b. indicus. being an important semi-wild bovid species, this has also been listed under the red list of international union of conservation of nature and natural resources. however, there is limited information available about the immunogenicity of this precarious spe ... | 2018 | 29666331 |
| pervasive introgression facilitated domestication and adaptation in the bos species complex. | species of the bos genus, including taurine cattle, zebu, gayal, gaur, banteng, yak, wisent and bison, have been domesticated at least four times and have been an important source of meat, milk and power for many human cultures. we sequence the genomes of gayal, gaur, banteng, wisent and bison, and provide population genomic sequencing of an additional 98 individuals. we use these data to determine the phylogeny and evolutionary history of these species and show that the threatened gayal is an i ... | 2018 | 29784979 |
| a national serosurvey to determine the prevalence of paratuberculosis in cattle in bhutan following detection of clinical cases. | johne's disease is an economically important ruminant disease predominantly affecting cattle, sheep and goats. the economic losses are due to early culling, reduced growth rate, progressive weight loss and reduced production. it is caused by mycobacterium avium subspecies paratuberculosis (map). johne's disease was reported in cattle in bhutan, based on clinical signs and histopathology; in the late 1990s samples from one mithun that was suspected to have died due to this disease was confirmed b ... | 2018 | 29974632 |
| high-density genotyping reveals genomic characterization, population structure and genetic diversity of indian mithun (bos frontalis). | the current study aimed at genomic characterization and improved understanding of genetic diversity of two indian mithun populations (both farm, 48 animals and field, 24 animals) using genome wide genotype data generated with illumina bovinehd beadchip. eight additional populations of taurine cattle (holstein and ndama), indicine cattle (gir) and other evolutionarily closely related species (bali cattle, yak, bison, gaur and wild buffalo) were also included in this analysis (n = 137) for compara ... | 2018 | 29985484 |
| administration of slow release exogenous melatonin modulates oxidative stress profiles and in vitro fertilizing ability of the cryopreserved mithun (bos frontalis) spermatozoa. | mithun (bos frontalis) is a unique domestic free range bovine species of north eastern hilly regions of india. the present study was designed to assess the seasonal effect of slow release exogenous melatonin (mt) implant on semen quality parameters (sqp) and in vitro zona binding ability (ivz) of spermatozoa. the experimental animals were divided into gr i: control (n = 5) and gr ii: treatment (n = 5; melatonin implant @ 18mg/50 kg bwt). a total of 20 semen samples/group in winter, spring, autum ... | 2018 | 30096619 |
| deletion/insertion polymorphisms of the prion protein gene (prnp) in gayal (bos frontalis). | resistance to fatal disease bovine spongiformencephalopathy (bse), due to misfolded prion protein in cattle, is associated with a 23-bp indel polymorphism in the putative promoter and a 12-bp indel in intron 1 of the prnp gene. gayal (bos frontalis) is an important semiwild bovid species and of great conservation concern, but till today these indel polymorphisms have not been evaluated in gayals. therefore, we collected 225 samples of gayals and evaluated the genetic indel polymorphism in the tw ... | 2018 | 30555062 |
| complete mitochondrial genome of indian mithun, bos frontalis and its phylogenetic implications. | mithun (bos frontalis) is an endangered domestic bovine species native to the hilly areas of china, bangladesh, myanmar, bhutan and india. it is believed to have been domesticated from gaur around 8000 years ago. however, a few studies suggest that mithun is either an independent species or a hybrid descendant of gaur and cattle. therefore, to understand the evolutionary history of mithun, the complete mitochondrial genome of indian mithun was sequenced and compared with the mitochondrial genome ... | 2019 | 30762166 |
| muscle transcriptome signature and gene regulatory network analysis in two divergent lines of a hilly bovine species mithun (bos frontalis). | a massive bovine, bos frontalis, also known as mithun or gayal, found at higher altitude is very promising meat and milk animal. for candidate gene and marker discovery, rna-seq data was generated from longissimus dorsi muscle tissues with illumina-hiseq. such markers can be used in future for genetic gain of traits like feed conversion efficiency (fce) and average daily gain (adg). analysis revealed 297differentially expressed genes (degs) having 173 up and 124 down-regulated unigenes. extensiv ... | 2020 | 30822468 |
| flaxseed oil modulates semen production and its quality profiles, freezability, testicular biometrics and endocrinological profiles in mithun. | mithun (bos frontalis) is a unique domestic free range bovine species of north eastern hilly (neh) regions of india. effect of feed supplementation of flaxseed oil (fso) on semen production and its quality profiles, freezability, oxidative stress, apoptotic sperm percentage and subsequently on endocrinological profiles & scrotal and testicular biometrics in different seasons was studied in mithun. the experimental animals were divided into two groups, gr i: control (n = 3) and gr ii: treatment ( ... | 2019 | 31247386 |
| whole genome sequence and de novo assembly revealed genomic architecture of indian mithun (bos frontalis). | mithun (bos frontalis), also called gayal, is an endangered bovine species, under the tribe bovini with 2n = 58 xx chromosome complements and reared under the tropical rain forests region of india, china, myanmar, bhutan and bangladesh. however, the origin of this species is still disputed and information on its genomic architecture is scanty so far. we trust that availability of its whole genome sequence data and assembly will greatly solve this problem and help to generate many information inc ... | 2019 | 31357931 |
| correction: impact of metal binding on the antitumor activity and cellular imaging of a metal chelator cationic imidazopyridine derivative. | correction for 'impact of metal binding on the antitumor activity and cellular imaging of a metal chelator cationic imidazopyridine derivative' by mithun roy et al., dalton trans., 2011, 40, 4855-4864. | 2019 | 31603176 |
| molecular characterization of blastocystis sp. in captive wildlife in bangladesh national zoo: non-human primates with high prevalence and zoonotic significance. | blastocystis sp. is a protozoan parasite, commonly found in the gastrointestinal tracts of animals and humans globally. the parasitic species has wide genetic diversity. currently the mammalian and avian isolates of the parasite are grouped into 17 well known subtypes (sts), of which ten (st1-st9, st12) are reported in humans. to assess the genetic diversity of blastocystis sp. in wildlife, a total of 200 fresh fecal samples were collected from 32 mammalian wildlife species in bangladesh nationa ... | 2019 | 31867211 |
| the composition of fungal communities in the rumen of gayals (bos frontalis), yaks (bos grunniens), and yunnan and tibetan yellow cattle (bos taurs). | the rumen is a microbial-rich ecosystem in which rumen fungi play an important role in the feed digestion of ruminants. the composition of rumen fungi in free-range ruminants such as gayals, yaks, tibetan yellow cattle, and the domesticated yunnan yellow cattle was investigated by sequencing an internal transcribed spacer region 1 (its1) using illumina miseq. a total of 285 092 optimized sequences and 904 operational taxonomic units (otus) were obtained from the four cattle breeds. the rumen fun ... | 2019 | 31880894 |
| directed modification of a ruminal cellulase gene (cmc-1) from a metagenomic library isolated from yunnan gayal (bos frontalis). | gayal (bos frontalis) of the yunnan region is well adapted to harsh environmental conditions. its diet consists predominantly of bamboo, reeds, and woody plants, suggesting that the rumen of this species contains many fiber-degrading bacteria and cellulases. the aim of this study was to identify and modify specific cellulases found in the gayal rumen. in the present study, a directed evolution strategy of error-prone pcr was employed to improve the activity or optimal temperature of a cellulase ... | 2020 | 32060600 |
| consequences of domestication on gut microbiome: a comparative study between wild gaur and domestic mithun. | although the gut microbiome benefits the host in several ways, how anthropogenic forces impact the gut microbiome of mammals is not yet completely known. recent studies have noted reduced gut microbiome diversity in captive mammals due to changes in diet and living environment. however, no studies have been carried out to understand how the gut microbiome of wild mammals responds to domestication. we analyzed the gut microbiome of wild and captive gaur and domestic mithun (domestic form of gaur) ... | 2020 | 32158434 |
| a genetically unique chinese cattle population shows evidence of common ancestry with wild species when analysed with a reduced ascertainment bias snp panel. | in hong kong, there is a cattle population of ~1,200 individuals of uncertain origin and genetic diversity. this population shows heterogeneous morphology, both in body type and pigmentation. once used as draught animals by the local farmers, they were abandoned around the 1970s due to changes in the economy, and since then have lived as feral populations. to explore the origins of these cattle, we analysed ~50k genotype data of 21 hong kong feral cattle, along with data from 703 individuals of ... | 2020 | 32271816 |
| slow release exogenous melatonin modulates scrotal circumference and testicular parameters, libido, endocrinological profiles and antioxidant and oxidative stress profiles in mithun. | mithun (bos frontalis) is a unique domestic free-range bovine species available in north eastern hilly (neh) regions of india and is reared for its protein rich meat. although, mithun suffers from severe non-cyclical population fluctuations, it is not yet declared as endangered. therefore, present study was conducted to assess the effect of slow release subcutaneous exogenous melatonin (mt) implant on sexual behaviour, scrotal circumference (sc) and testicular parameters, endocrinological profil ... | 2020 | 32470703 |
| the complete mitochondrial genome of indian gaur, bos gaurus and its phylogenetic implications. | the gaur is the largest extant cattle species and distributed across south and southeast asia. around 85% of its current global population resides in india, however there has been a gradual decrease in the gaur population over the last two decades due to various anthropogenic activities. mitochondrial genome is considered as an important tool for species identification and monitoring the populations of conservation concern and therefore it becomes an obligation to sequence the mitochondrial geno ... | 2020 | 32686769 |
| evolution and domestication of the bovini species. | domestication of the bovini species (taurine cattle, zebu, yak, river buffalo and swamp buffalo) since the early holocene (ca. 10 000 bce) has contributed significantly to the development of human civilization. in this study, we review recent literature on the origin and phylogeny, domestication and dispersal of the three major bos species - taurine cattle, zebu and yak - and their genetic interactions. the global dispersion of taurine and zebu cattle was accompanied by population bottlenecks, w ... | 2020 | 32716565 |
| bluetongue in india: a systematic review and meta-analysis with emphasis on diagnosis and seroprevalence. | bluetongue (bt) is an infectious viral disease which affects a wide range of ruminants and was first reported in india in 1964. in view of the absence of comprehensive information on the bt status in india, this study presents the seroprevalence on bt in farm animals of india based-on a systematic review and meta-analysis. a systematic review was conducted to identify the published articles (2001-2018) reporting the seroprevalence of bt in sheep, goats, cattle, buffalo, camels, and mithun (bos f ... | 2020 | 32886028 |