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comparison of the gonadal response of wild and laboratory field voles (microtus agrestis) to different photoperiods.weanling male and female field voles from laboratory stock and from the f1 generation of wild-caught animals were placed in a long (16l:8d) or short (6l:18d) photoperiod for 28 or 56 days. both types of field vole showed the well-established effect of photoperiod upon sexual maturation, with animals in the long photoperiod having larger and more active gonads than animals in the short photoperiod. after 28 and 56 days laboratory stock females were more mature, sexually, and had a higher growth r ...19873546683
serological studies of british leptospiral isolates of the sejroe serogroup. iii. the distribution of leptospires of the sejroe serogroup in the british isles.some 94 strains of leptospires belonging to the sejroe serogroup isolated in the british isles were identified to the serovar level using specific factor sera. seventy strains were identified as leptospira interrogans serovar hardjo, 66 from cattle, 2 from pigs and 1 each from a sheep foetus and a human. twenty-four strains were identified as l. interrogans serovar saxkoebing, most strains were isolated from either wood mice, bank or field voles but strains were also isolated from badgers, a fox ...19873609169
basic carriers of trichophyton mentagrophytes var. gypseum in the sverdlovsk region.tests for myococarriers were made on 4.297 wild small mammals. clinical examinations only were carried out on 1,204 animals, both clinical and laboratory examinations on 3,093 animals. the suppurative form of trichophytosis was diagnosed in only one specimen of microtus oeconomus out of 1,204 animals examined. t. ectothrix microides was found in the hair taken from the focus. t. mentagrophytes var. gypseum was obtained by culture on nutrient media. no clinical signs of mycosis were found in 3,09 ...19873680938
dnase i sensitivity in facultative and constitutive heterochromatin.in situ nick translation allows the detection of dnase i sensitive and insensitive regions in fixed mammalian mitotic chromosomes. we have determined the difference in dnase i sensitivity between the active and inactive x chromosomes in microtus agrestis (rodent) cells, along both their euchromatic and constitutive heterochromatic regions. in addition, we analysed the dnase i sensitivity of the constitutive heterochromatic regions in mouse chromosomes. in microtus agrestis female cells the activ ...19853905296
[the effect of methylnitronitrosoguanidine on dna synthesis in human and animal cells. inhibition of dna synthesis in asynchronous and synchronous cultured cells].methylnitronitrosoguanidine (mnng) is reported to inhibit dna synthesis in intact human cells, in the cells from patients with ataxia telangiectasia (at) or the cells from two rodent species. dna synthesis in different cell lines exhibits varying sensitivity to mnng inhibitory effect. 4-5-fold higher concentrations of mnng are required for 50% inhibition of dna synthesis in at cells or in field vole cells as compared with the concentration required for human cells or chinese hamster. the differe ...19853916233
localization of repetitive dna in the chromosomes of microtus agrestis by means of in situ hybridization. 20144104367
sebaceous glands on the hindquarters of the vole, microtus agrestis. 19724119254
fluorescence banding pattern of the chromosomes of microtus agrestis with a benzimidazol derivative. 19734126706
the repeated dna sequences of microtinae. i. microtus agrestis, microtus pennsylvanicus and ellobius lutescens. 19734128137
application of an established diploid microtus agrestis cell line as a model for the understanding of mammalian heterochromatin. 19744131765
fluorochromes and heterochromatin. a study of the chromosomes of microtus agrestis l. 19714142019
seasonal changes of pelage in the vole (microtus agrestis). 3. the role of the endocrine system. 19714323875
the induction of tumours with rous sarcoma virus in microtus agrestis: a preliminary note. 19704325786
photoperiodic control of testis activity in the vole, microtus agrestis. 19744415059
seasonal dynamics of parasitocoenosis in field-vole (microtus arvalis, pallas, 1778) populations living in large-acreage lucerne fields. 19744454298
the concurrence of two species of nematodes of the genus heligmosomum in a field-vole (microtus arvalis) population in large-acreage lucerne fields. 19744454301
social environment and ovulation in the vole, microtus agrestis. 19744473548
field and laboratory studies on the control of luteinizing hormone secretion and gonadal activity in the vole, microtus agrestis. 19734522408
the c-band and g-band patterns of microtus agrestis chromosomes. 19724561269
polyploidization in vitro: formation of a predominantly triploid cell population in an originally diploid tissue culture of microtus agrestis. 19744600713
seasonal changes in pituitary prolactin and growth hormone content of field voles in different reproductive states (microtus arvalis pall., rodentia). 20154619281
loss of heteropycnosis of the constitutive heterochromatin in specifically activated cells of the thyroid gland of microtus agrestis. 19734693092
[amino acid composition of blood proteins of field voles (microtus oeconomus pall.), living in different radioecological conditions]. 20034780543
the development of the ovary from birth to maturity in the bank vole (clethrionomys glareolus) and the vole (microtus agrestis). 19744829082
heterochromatin and chromosomal aberration in microtus agrestis: role of chromosomal association. 19744842085
[structure and position of heterochromatic chromosomes in interphase nuclei of microtus agrestis]. 19694900457
the fine structure of babesia microti in the natural host, microtus agrestis. 19704992453
a study of spermatogenesis in the developing and mature vole (microtus agrestis). 19725017010
pattern of repetitive dna of the chromosomes of microtus agrestis. 19725025666
fluorescence of constitutive heterochromatin of microtus agrestis. 19725036994
a cytoplasmic organelle in adenohypophysial cells of the vole, microtus agrestis. 20165070833
tritiated uridine induced chromosome aberrations in relation to heterochromatin and nucleolar organisation in microtus agrestis l. 19715096941
radiation-induced deletions and translocations of microtus agrestis sex chromosomes in vivo. 19715097521
a developmental study of constitutive heterochromatin in microtus agrestis. 19715103061
constitutive heterochromatin in microtus agrestis: binding of actinomycin-d and transcriptional inactivity. 19715116080
cytological variations in the constitutive heterochromatin of microtus agrestis. 19715131757
isolation, fractionation and biochemical analysis of the metaphase chromosomes of microtus agrestis. 19715131758
the morphology and life-history of trypanosoma (herpetosoma) microti of the field-vole, microtus agrestis. 19695372140
[deletion and translocation of heterochromatic chromosome segments of microtus agrestis]. 19695391960
[distribution of radiation-induced breaks in the sex chromosomes of microtus agrestis]. 19695391961
differential rna synthesis of eu- and heterochromatin in microtus agrestis. 19705412268
constitutive heterochromatin during early embryogenesis of microtus agrestis. 19705413549
ovulation and associated histological changes in the ovary following coitus in the vole (microtus agrestis). 19705421106
genetic inactivity of heterochromatin and heteropycnosis in microtus agrestis. 19705436406
expression of constitutive heterochromatin in cultured fibroblasts from microtus agrestis. 19705459844
quantitative autoradiography of heterochromatin replication in microtus agrestis. 19705480728
ovarian changes during pregnancy and pseudopregnancy in the vole, microtus agrestis. 19705492027
the electron microscopy of the adenohypophysis of the vole, microtus agrestis. 19705500821
hypothalamic influence on pituitary and serum levels of lh in the vole, microtus agrestis. 19705500823
deletions of the x chromosomes in microtus agrestis cells in vitro. 19705519129
effect of photoperiod on ovarian function in the vole, microtus agrestis. 19705528678
louping-ill and semliki forest virus infections in the short-tailed vole microtus agrestis (l.). 19705530345
seasonal changes of pelage in the vole (microtus agrestis). i. correlation with changes in the endocrine glands. 19715550926
seasonal changes of pelage in the vole (microtus agrestis). ii. the effect of daylength. 19715550927
hypothalamo-hypophysial control of ovulation in the vole (microtus agrestis). 19715558384
repetitive dna of microtus agrestis. 19715563308
[pairing behaviour of the sex chromosomes during male meiosis of microtus agrestis]. 19715574764
binding of actinomycin d to constitutive heterochromatin in microtus agrestis. 19715580888
the chromosomes of long term cultivated field-vole cells. 19675585054
[seasonal and age variations in the skeletal dose of radiation due to incorporated strontium 90 in field voles under natural conditions]. 20035608542
interrupted ongoing behaviour in two species of vole (microtus agrestis and clethrionomys britannicus). i. response as a function of preceding activity and the context of an apparently "irrelevant" motor pattern. 19685639892
interrupted ongoing behaviour in two species of vole (microtus agrestis and clethrionomys britannicus). ii. extended analysis of motivational variables underlying fleeing and grooming behaviour. 19685639894
pregnancy-block in microtus agrestis and induced ovulator. 19685668444
formation and division of binucleated cells in kidney cell cultures of microtus agrestis. 19685704434
a biochemical and ecological study of plasma esterase polymorphism in natural populations of the field vole, microtus agrestis l. 19685707672
oestrus and ovarian histology in the lactating vole (microtus agrestis). 19695791681
[distribution of chromosomes to the daughter cell nuclei of multipolar mitoses in euploid tissue cultures of microtus agrestis]. 19695800669
the relation of sex chromosomes to chromocenters in somatic cells of microtus agrestis (l.). 19655826652
[on the neurosecretory hypothalamo-hypophyseal system in rodents: the field mouse (microtus agrestis)]. 19655826828
[dna reduplication pattern in the giant sex chromosomes of microtus agrestis]. 19655857561
the fine structure of the sex vesicle and sex chromosome association in spermatocytes of mouse, golden hamster and field vole. 19665972764
trichophyton persicolor infection in the field vole and pipistrelle bat. 19666006211
changes in the hypothalamo-hypophysial neurosecretory system and the gonads of the vole (microtus agrestis). 19676034721
effect of light and temperature upon gonad activity in the vole (microtus agrestis). 19676034722
a serum esterase variation in microtus agrestis (l.). 19676064102
resistance of the short-tailed vole microtus agrestis (l.) to infection with two arboviruses. 19676075434
[studies of the ecology of some blood protozoa of wild small mammals in north germany (author's transl)].in 1977 and 1978, 696 small mammals of 9 different species were surveyed for protozoal blood parasites. the following parasites were found: hepatozoon sylvatici in apodemus flavicollis, h. erhardovae and trypanosoma evotomys in clethrionomys glareolus, t. microti and babesia microti in microtus agrestis and t. croicidurae in crocidura russula. h. erhardovae showed regularly high infection-rates (more than 70%) during all the years in 1977 and 1978. h. sylvatici was found only in 5.6% of the yell ...19806104423
[demonstration of the virus of hemorrhagic fever with renal syndrome in the organs of rodents from natural foci of the infection in the ussr and the serodiagnosis of the diseases].an indirect fluorescent antibody test (ifat) and an enzyme-immunological test (elisa) were used for the detection of hfrs virus in organs of rodents from hfrs foci in the ussr. the virus was found in 115 out of 1120 bank voles, 9 out of 92 redbacked voles, and 2 field voles examined. spontaneous infection-rate of bank voles in population varied from 1.3 to 100% correlating with the epidemiological situation in foci. ifat and elisa were successfully used for serodiagnosis of hfrs. examinations of ...19816121425
[transmission and course of parasitemia of babesia microti (hannover i strain) in the bank vole (clethrionomys glareolus) and field vole (microtus agrestis)].in germany only m. agrestis has been found to be naturally infected with b. microti while in other european countries several rodent species were found as mammalian hosts. in the laboratory c. glareolus got easily infected by german strains of b. microti, if parasitized blood was inoculated. but results of this method are not transferable to natural conditions. therefore this study was carried out. it was to prove whether c. glareolus is susceptible to b. microti transmitted by nymphs of i. rici ...19846150621
association of pp60src and src protein kinase activity with the plasma membrane of nonpermissive and permissive avian sarcoma virus-infected cells.the intracellular localization of pp60src and src protein kinase activity in avian sarcoma virus (asv)-infected chicken embryo fibroblasts and transformed and morphologically reverted field vole cells was examined by subcellular fractionation procedures. fractionation by differential centrifugation of dounce-homogenized cellular extracts prepared from vole cells showed that 83 to 91% of pp60src sedimented with particulate subcellular components from both transformed and revertant vole cells. a s ...19806257928
loss of tumorigenicity correlates with a reduction in pp60src kinase activity in a revertant subclone of avian sarcoma virus-infected field vole cells.we have recently isolated an interesting revertant subclone (revertant 866-4) of esv-infected field vole cells that is indistinguishable from uninfected vole cells with respect to its lack of transformed cell properties. these revertants are not only normal morphologically, but they do not grow in soft agar and are nontumorigenic in athymic nude mice. despite this lack of transformed cell properties, we have found that this cell line still contains pp60src at concentrations (0.30 microgram/mg ce ...19816261958
karyotype analysis and quantitation of viral transforming genes in rous sarcoma virus transformed, revertant, and retransformed field vole cells.comparative studies of the number of cellular chromosomes and viral genes, including the gene required for malignant transformation, were performed on several clones of rous sarcoma virus-transformed, revertant, and spontaneously retransformed field vole cells. the results of these studies indicate that no appreciable differences in either total viral gene equivalents or transforming gene sequences can be detected between transformed and revertant cell types, even though considerable differences ...19816262017
increase in the phosphotransferase specific activity of purified rous sarcoma virus pp60v-src protein after incubation with atp plus mg2+.pp60v-src, the product of the rous sarcoma virus src gene, was partially purified by immunoaffinity chromatography from extracts of rous sarcoma virus-transformed field vole cells. incubation of this preparation with atp plus mg2+ and subsequent repurification by chromatography on hexylamine-agarose resulted in a net increase in the specific activity of the src protein kinase. this increase in phosphotransferase activity was detected by using a variety of substrates including casein, tubulin, an ...19836314123
pineal influences hypothalamic gn-rh content in the vole, microtus agrestis. 19836339718
postnatal development of intestinal villi in the field vole (microtus montebelli): a scanning electron microscopic study. 19836358986
identification of a reservoir of leptospira interrogans serovar muenchen in voles (microtus agrestis and clethrionomys glareolus) in england.infection with leptospires of the australis serogroup is widespread in voles in southern england and the serovar identification of five randomly-selected isolates was determined by cross agglutination absorption. two isolates from short-tailed voles (microtus agrestis) and three isolates from bank voles (clethrionomys glareolus) were all identified as serovar muenchen. the only previous isolation of this serovar is that from a human in germany.19836372316
observations on uterine mast cells during early pregnancy in the vole, microtus agrestis.the vole, microtus agrestis, was chosen for this study of mast cells during early pregnancy because this species does not show spontaneous estrous cycles. mast cell numbers in the uterus are known to vary during the estrous cycle in some species (rat, cow, syrian hamster). mast cell changes during early pregnancy in the vole could not reflect hormonal changes which had occurred during a preceding estrous cycle. mast cells in the uterus (myometrium, endometrium, and mesometrial triangle) and ear ...19846375459
microtus species as new herbivorous laboratory animals: reproduction; bacterial flora and fermentation in the digestive tracts; and nutritional physiology.in a study of the possible introduction of japanese field vole (microtus montebelli ) and hungarian voles (m. arvalis) as herbivorous experimental animals, the following biological characteristics were investigated: breeding and reproductive performance; bacterial flora and fermentation in the digestive tracts; and nutritional physiology. the animals are polyestrus , show postpartum estrus on the day of parturition, and there is little or no delay in implantation due to lactation, especially in ...19846377675
effect of mating on the metabolic activity of the brain and pituitary gland assessed by [14c]2-deoxyglucose in a reflex ovulator, the vole (microtus agrestis).the neural pathways involved in reflex ovulation in the vole (microtus agrestis) have been investigated with the [14c]2-deoxyglucose (2-dg) method. female voles were injected i.p. with 2-dg and either not mated, sham-mated (mounted by males by vagina was taped) or mated for a period of 45 min after the injection, after which the animals were decapitated. the brain was processed for autoradiography and the relative metabolic activities (rma) of selected areas of the brain and pituitary gland were ...19846388729
[breeding and rearing of japanese field voles (microtus montebelli milne-edwards) and hungarian voles (microtus arvalis pallas) as new herbivorous laboratory animal species].microtus species are very useful as experimental small animals with herbivorous characteristics. in this report, to approach establishment of the use of japanese field voles (m. montebelli) and hungarian voles (m. arvalis) as experimental animals, the biological characteristics, breeding methods and reproductive performance of these animal species were comparatively investigated. the number of chromosomes of m. arvalis is 12n = 46, differing from those of m. montebelli, 2n = 30. the breeding and ...19826754391
cell cycle-dependent regulation of excision repair of uv damage.the incision step of excision repair of uv-damaged dna, represented by the accumulation of dna strand breaks in the presence of hydroxyurea and 1-beta-d-arabinofuranosylcytosine, was measured in cultured cells of microtus agrestis during quiescence and at different times after release from quiescence. the uv dose-dependent kinetics of enzymic incision change rapidly through the first cell cycle after release, with a maximum potential for enzymic incision and a minimum affinity of the incision sy ...19826754399
feulgen-dna changes in the germ cells of the male vole (microtus agrestis) during their development.consistent with changes in ploidy during germ cell maturation, the quantity of feulgen dna in round spermatids of voles is approximately a quarter of that in primary spermatocytes. the amount increases slightly in elongated spermatids, and then declines in spermatozoa from the testis, epididymis and vas deferens, below the level of round spermatids. simultaneously nuclear area decreases so that in spermatozoa it is about one tenth that of primary spermatocytes. the rise in feulgen dna in elongat ...19806760273
[occurrence of white japanese field vole (microtus montebelli) in the laboratory].some field voles with a white coat color were found in the breeding process in the laboratory, originated from a wild population captured in the riverside of the arakawa in okegawa, saitama prefecture in japan. they had been raised in a room and fed with pelleted feed for herbivore. an attempt was made to analyze their breeding records and mode of inheritance for the white coat color. as a result, the average litter size was 3.80 +/- 1.52, and the age of the first birth was 121 +/- 46.8 in days. ...19826762967
[the life-history of sarcocystis singaporensis zaman and colley, 1976 in the definitive and intermediate host (author's transl)].sporulated oocysts and sporocysts (9.3 x 7.3 micrometer) of sarcocystis singaporensis - isolated from freshly imported snakes (python reticulatus) - were fed to various animals to test their function as suitable intermediate hosts (nmri-mice, albino rats, meriones unguiculatus, golden hamsters, guinea pigs, mastomys natalensis, field-voles [microtus arvalis], pigeons, and chickens). only in rats were muscle-cysts formed. the optimal dose was 150 sporocysts per rat. two generations of merogony co ...19806771934
gonadotrophin levels in male voles (microtus agrestis) reared in long and short photoperiods.male voles were reared from birth to the age of 56 days in photoperiods of 16l:8d or 6l:18d. in 16l:8d testes increased 10-fold in size between the age of 14 and 56 days, and there were concomitant increases in diameter of seminiferous tubules and seminal vesicle weight. spermatozoa were present in tubules by 35 days. in 6l:18d no significant changes with age occurred in testis size, diameter of seminiferous tubules or seminal vesicle weight. lh secretion increased with age in 16l:8d, but not in ...19826816930
prevalence of pneumocystis carinii delanoë & delanoë, 1912 in rodents in denmark.pneumocystis carinii has been found in 17 of 90 (19%) wild living trapped brown rats (rattus norvegicus). the positive brown rats originated from about 25% of the trapping localities examined. among brown rats of two breeding stocks, h and s, pneumocysts were found in 43.5% of the h rats, but in none of the s rats. by keeping brown h rats on a low protein diet for 8 weeks, it was possible to augment the prevalence to 53.8%. pneumocystis carinii has furthermore been found in one of eight (12.5%) ...19806965782
effect of bromocriptine treatment on the ovulatory response to oestradiol benzoate in the reflex ovulator, microtus agrestis.in some animals which ovulate spontaneously, oestrogen may stimulate prolactin secretion and high levels of prolactin may inhibit steroid-induced surges of lh. the possibility was investigated that such conditions were operating in the reflex ovulator microtus agrestis to prevent spontaneous ovulation. however, bromocriptine treatment to suppress prolactin secretion did not enhance the poor ovulatory response to administration of oestradiol benzoate.19806988538
a note on the ploidy of purkinje cells; sex chromatin in field vole (microtus agrestis) and man.examination of sex chromatin bodies in purkinje cell nuclei suggests only a diploid chromosomal content: there is no increase in number or size above that seen in diploid cells.19806990292
allozyme variation in natural populations of field vole (microtus agrestis l.). i. survey of the 'semi-stable' population in southern sweden. 19806991456
cerebrospinal fluid-contacting area in the pineal recess of the vole (microtus agrestis), guinea pig (cavia cobaya), and rhesus monkey (macaca mulatta).the ventricular lining in the pineal recess of the vole (microtus agrestis), guinea pig (cavia cobaya) and rhesus monkey (macaca mulatta) was investigated light and electron microscopically. deep in the pineal recess of all three species the ependymal lining exhibits interruptions. a varying proportion of pinealocytes penetrates through this ependymal area, so that the surface of the protruding cells is directly exposed to the cerebrospinal fluid (csf). at their base, these cells are anchored in ...19806996824
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