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comparison of the virion polypeptides of group b arboviruses.the virion polypeptides of eight group b arboviruses were compared by polyacrylamide gel coelectrophoresis. all contained three polypeptides, v-1, v-2, and v-3. the mosquito-borne viruses had electrophoretically similar small membrane polypeptides (v-1); the tick-borne viruses had a v-1 of significantly decreased mobility.19724144016
use of the sodium deoxycholate sensitivity test in cell cultures. 19734147146
isolation of st. louis encephalitis and cache valley viruses from saskatchewan mosquitoes. 19734147200
studies on the sequential immunization against group b arboviruses in squirrel monkeys, cynomolgus monkeys, rhesus monkeys, and chimpanzees. 19744204022
[role of birds in importing and preserving arboviruses (a review of the literature)]. 19744213786
[detection of antibodies to a series of arboviruses of groups a, b and bunyamwera on the territory of the georgian ssr]. 19724260426
[epidemiological study of japanese encephalitis in hokkaido. 2. serological survey of japanese encephalitis virus infection for residents of hokkaido]. 19714335385
serologic evidence of arbovirus activity in a moose population in alberta. 19714361127
arbovirus serology in north dakota mule and white-tailed deer. 19734361503
cross-protection between group b arboviruses: resistance in mice to japanese b encephalitis and st. louis encephalitis viruses induced by dengue virus immunization.albino swiss mice, immunized with any of several types and strains of dengue viruses, were afforded substantial protection against peripheral japanese b encephalitis or st. louis encephalitis virus challenge. dengue-2 (new guinea "c")-immunized mice showed, 10 and 20 weeks after immunization, undiminished resistance with concomitant cyclophosphamide treatment and virus challenge. examination of the effects of immunization on japanese b encephalitis virus pathogenesis, after virus challenge with ...19744363234
lead aggravates viral disease and represses the antiviral activity of interferon inducers.lead acetate was administered continuously in the drinking water to cd-1 male mice beginning at 4 weeks of age. an ld(10-20) of the lytic viruses or 300 plaque-forming units of rlv was inoculated intrapertioneally at 6 weeks of age. lead increased the response of the mice to all classes of viruses against which it was tested: an rna picornavirus-encephalomyocarditis (emcv), a dna herpesvirus-pseudoribies, an rna leukemia-virus-rauscher leukemia (rlv), an rna arbovirus b-st. louis encephalitis, a ...19744364644
viral infection and lipemia: a problem of disordered host physiology. 19744366424
virus infections in bats. 19744367453
isolation of st. louis encephalitis virus from man in argentina. 19714396413
on the japanese b--west nile virus complex or an arbovirus problem of six continents. 19714396497
rapid identification of an arbovirus by observation on its morphogenesis in the electron microscope. 19714398898
mosquitoes of british honduras, with some comments on malaria, and on arbovirus antibodies in man and equines. 19714400502
agents encountered during arboviral ecological studies: tampa bay area, florida, 1963 to 1970. 19724400812
effect of tween 80 on the haemagglutinating activity of group b arboviruses. 19724404098
neutralizing antibody against akabane virus in precolostral sera from calves with congenital arthrogryposis-hydranencephaly syndrome. 19744451432
[arbovirus diseases. antibodies against st louis encephalitis in mental patients]. 19744456515
[molecular biological characteristics of arbovirus macromolecules and their biosynthesis]. 19724566001
st. louis encephalitis virus: an ultrastructural study of infection in a mosquito vector. 19734583310
etiologies of the experimental dengues of siler and simmons.four participants in the american army philippine dengue (d) studies of siler (1924-25) and five subjects from the studies of simmons (1929-30) were bled 42 to 48 years after experimental infection. sera were studied by hemagglutination-inhibition, complement-fixation and plaque reduction neutralization (prnt) tests for antibodies to the known viral causes of the dengue syndrome in asia and to st. louis encephalitis virus. prnt tests were done with and without fresh normal human serum (accessory ...19744615598
california encephalitis virus isolations from yukon mosquitoes, 1971. 19724622645
saint louis encephalitis viral ribonucleic acid replication complex.pulse-labeled saint louis encephalitis viral ribonucleic acid (rna) is found in the cytoplasm of infected cells associated with a membranous structure which sediments with an average value of 250s. the integrity of the complex is destroyed by detergents and ribonuclease; however, it is stable in ethylenediaminetetraacetic acid (edta) which differentiates this structure from cellular polyribosomes. with cultures in which cellular rna was highly labeled prior to infection, ribosomal rna could not ...19724623222
proteins specified by group b togaviruses in mammalian cells during productive infections. 19734632654
elimination of repeated clot formation in mouse ascitic fluid containing arbovirus antibodies.repeated clot formation in mouse ascitic fluids containing antiviral antibody was eliminated by acid precipitation of the fibrinogen.19724672320
considerations on the ecology of several arboviruses in eastern long island. 19734684881
wildlife as monitors of disease. 19734687867
house sparrows, passer domesticus (l.), as hosts of arboviruses in hale county, texas. i. field studies, 1965-1969. 19734688420
the effect of environmental temperature upon the transmission of st. louis encephalitis virus by culex pipiens quinquefasciatus. 19734697417
virological studies of avian hosts in the houston epidemic of st. louis encephalitis, 1964. 19734729745
urban st. louis encephalitis surveillance through wild birds. 19744825600
assessment of bird involvement in three urban st. louis encephalitis epidemics. 19744825601
influence of sex and age on natural resistance to st. louis encephalitis virus infection in mice.a difference was observed in susceptibility of adult male and female mice to st. louis encephalitis (sle) virus as measured by the death rate after intravenous challenge. female mice that had susceptibility similar to that of males at 2 months of age had increased resistance to sle virus at 3 and 4 months of age. the increased resistance occurred after sexual maturity, indicating that the resistance factor possibly was related to an aging process in the female. the susceptibility of male mice re ...19744857422
st. louis encephalitis virus infection in mice. electron microscopic studies of central nervous system. 19684974186
stability of st. louis encephalitis virus in the airborne state.the aerosol stability of st. louis encephalitis (sle) virus was studied over a 6-hr period at a temperature of 21 c and relative humidity values of 23, 46, 60, and 80%. aerosols were generated from and collected in 0.75% bovine albumin-buffered saline, and spores of bacillus subtilis var. niger were used as the tracer to determine the physical decay of the aerosols. aerosol samples were titrated in bhk-21 cell monolayers for surviving sle virus. the results of this study indicated that, under th ...19694984205
arbovirus infections in man in british columbia.during the summer of 1971, the first laboratory-proved cases of acute encephalitis in man due to any of the known arboviruses occurred in the south-central region of british columbia. five human cases of encephalitis with two deaths were diagnosed; three of these patients, including one of the fatalities, were proven in the laboratory to have contracted western equine encephalitis.during 1968 and 1969, a human serum survey undertaken in approximately 2000 life-long residents of the province disc ...19725034698
recurrent st. louis encephalitis infection in residents of a flood plain of the trinity river, roosevelt heights (dallas, texas). 19725048980
structural and nonstructural proteins of saint louis encephalitis virus.analysis of purified saint louis encephalitis (sle) virus by acrylamide gel electrophoresis revealed that the virions contained three structural proteins designated sp-1, sp-2, and sp-3 which had molecular weights of 63,000, 18,000, and 8,500, respectively. the envelope contained proteins sp-1 and sp-3 which were removed from the nucleocapsid by nonionic detergent treatment. nucleocapsids prepared by deoxycholate treatment of complete virions had a density of 1.301 in potassium tartrate and cont ...19715102427
effects of thorotrast on humoral antibody, viral multiplication, and interferon during infection with st. louis encephalitis virus in mice. 19715111885
influence of age on infection with st. louis encephalitis virus. 19715111888
trinity river serologic survey. a survey of residents of communities along the course of the trinity river between houston and dallas, texas, for antibodies to the viruses of st. louis encephalitis, western equine encephalitis and california encephalitis. 19715120543
hemagglutination inhibition with arboviruses: relationship between titers and source of erythrocytes.antigens for grand arbaud, hazara, and california arboviruses were able to agglutinate goose and either dog, hamster and guinea pig, or hamster red blood cells (rbc) to the same titer at the same ph; in hemagglutination-inhibition (hi) tests, titers for homologous and related sera were the same with these different types of rbc or occasionally one dilution higher with the mammalian cells. antigens for st. louis encephalitis and eastern equine encephalitis viruses required use of lower antigen di ...19715165837
[the mechanism of interferon induction and its effect in tissue culture arbovirus infections]. 19715167615
[cultivation of various arboviruses in new transplantable lines of mouse fibroblasts]. 19715168877
[study of the interaction between st. louis encephalitis virus and tissue culture cells]. 19695356187
interferon in human infections with st. louis encephalitis virus. 19695360284
[the effect of beta-propiolactone and heat on the antigenic properties of a series of arboviruses]. 19695407009
persistence of antibodies to st. louis encephalitis virus in survivors of florida epidemics. 19705445645
studies of arthropod-borne virus infections in chiroptera. 8. evidence of natural st. louis encephalitis virus infection in bats. 19705453911
virus-induced cataracts. incidence and development in rats after intracerebral inoculation of st. louis encephalitis virus. 19685635093
experimental cyclic transmission of st. louis encephalitis virus in chickens and culex mosquitoes through a year. 19685652338
isolations of st. louis encephalitis virus from post-mortem tissues of human cases in the 1962 florida epidemic. 19685654947
synthesis of saint louis encephalitis virus ribonucleic acid in bhk-21-13 cells.infection of baby hamster kidney cells (bhk-21/13) with saint louis encephalitis (sle) virus depressed the rate of protein and ribonucleic acid (rna) synthesis until viral rna synthesis began 6 hr postinfection (pi). virus-directed rna synthesis was subsequently inhibited until 12 hr pi when virion maturation began. the rate of protein synthesis reached a peak 6 hr pi and was subsequently depressed until just before the onset of virion maturation. density gradient analysis of phenol-extracted rn ...19695771965
arbovirus studies in the ohio-mississippi basin, 1964-1967. ii. st. louis encephalitis virus. 19695817890
transovarian transmission of hemagglutination-inhibition antibody to st. louis encephalitis virus in chickens. 19655840641
[some factors affecting the multiplication of st. louis encephalitis virus cultured in hela cells and human amnion cells]. 19655865560
preparation of inactivated st. louis encephalitis virus vaccine from hamster kidney cell culture. 19665924439
effect of previous dengue infection and yellow fever vaccination on st. louis encephalitis virus serological surveys in tampa bay area of florida. 19665934624
experimental vector studies with strains of st. louis encephalitis virus isolated from mosquitoes during the 1964 epidemics. 19665986746
st. louis encephalitis virus from mosquitoes in southwestern indiana, 1964. 19665986756
isolation of st. louis encephalitis virus from a naturally-infected gray fox urocyon cinereoargenteus. 19676028561
recurring st. louis encephalitis virus infection at an urban homesite. 19676067464
[prevalence of antibodies against st. louis encephalitis virus in various marine birds from panama]. 19846093203
purification of the structural and nonstructural proteins of st. louis encephalitis virus.we have developed a procedure for purifying both the structural and nonstructural proteins of flaviviruses from lysates of infected cell cultures. the procedure involves: immunoprecipitation to concentrate viral proteins and eliminate most of the cellular proteins, preparative polyacrylamide gel electrophoresis to separate the viral proteins, and hydroxyapatite chromatography, which eliminates most of the unlabeled cellular protein. this procedure offers an improvement over previous purification ...19846099371
virus isolations from mosquitoes in southern ontario, 1976 and 1977.following the 1975 epidemic of st. louis encephalitis (sle) in ontario, programs were instituted to monitor virus activity in mosquito populations during 1976 and 1977. mosquitoes were trapped with cdc light traps and co2 cone traps, pooled by species, and tested for virus by intracerebral inoculation of suckling mice. in 1976, 51 175 mosquitoes were tested. sle virus was isolated from two mixed pools of culex pipiens--c. restuans mosquitoes. five isolations of california serogroup viruses were ...19806103747
st. louis encephalitis: a comparison of two epidemics in harris county, texas.the frequency and distribution of cases in two epidemics of st. louis encephalitis in houston, texas are compared by age, sex, race, season, duration, geographic area and resources available. the second epidemic was far less severe than the first. the influence of community intervention on the observed differences between the two epidemics is discussed.19816109458
replication of dengue, yellow fever, st. louis encephalitis and vesicular stomatitis viruses in a cell line (tra-171) derived from toxorhynchites amboinensis.the replication of seven arboviruses in a cell line (tra-171) derived from a nonhematophagous mosquito was studied. four serotypes of laboratory adapted and three serotypes of unadapted dengue viruses replicated in the tra-171 cell line, inducing syncytia. the sensitivity of tra-171 cells to dengue virus infection was comparable to that of aedes albopictus or a. pseudoscutellaris cells. yellow fever, st. louis encephalitis, and vesicular stomatitis viruses also replicated. all four serotypes of ...19816119288
the importance of disease induced changes in mammalian body temperature to mosquito blood feeding.laboratory mice infected with rodent malaria (plasmodium berghei or p. chabaudi) or st. louis encephalitis virus (sle) were not hyperthermic during the infection period. however, all infected animals displayed pathogen-specific periods of hypothermia. hamsters infected with p. berghei were hyperthermic on day 7 postinfection (pi) but became hypothermic on day 8 pi and remained so until death, approximately 20 days pi. body temperatures of mice infected with p. yoelii were not significantly diffe ...19846142803
[biological studies of st. louis encephalitis virus in majé, bayano]. 19846149603
evaluation of the solid-phase radioimmunoassay for diagnosis of st. louis encephalitis infection in humans.since the use of highly purified viral proteins in the solid-phase radioimmunoassay (spria) procedure is not practical for routine diagnostic serology, the procedure was adapted for use with the crude antigens now commonly used to diagnose st. louis encephalitis (sle) virus infections. sle and various other alpha- and flavivirus antigens were tested by both the spria procedure and conventional serological methods. standards were established for use of the crude antigens in the spria procedure. r ...19816168650
interferon-mediated persistent infection of saint louis encephalitis virus in a reptilian cell line.a persistent infection with saint louis encephalitis (sle) virus in a poikilothermic cell line th-1 (turtle heart cells) was studied. infected th-1 cells were subcultured weekly at 31 degrees c for 1 year and continued to produce low levels (10(2) to 10(3) p.f.u./ml) of virus without obvious cytopathic effects or marked cyclic events. indirect fluorescent antibody and infectious centre assays indicated that less than 1% of the cells were producing detectable virus proteins or infectious virus. d ...19826181191
st. louis encephalitis virus temperature-sensitive mutants. i. induction, isolation and preliminary characterization.nine temperature-sensitive (ts) mutants of st. louis encephalitis virus were isolated after "forced mutagenesis" with 5-fluorouracil or 5-azacytidine. the ts mutants could be grouped on the basis of rna synthesis at 40 degrees c, the nonpermissive temperature and complementation analysis. four complementation groups were identified. members of two of the groups were negative for rna synthesis at 40 degrees c while the remainder were positive.19836188441
identification of epitopes on the e glycoprotein of saint louis encephalitis virus using monoclonal antibodies.twenty-one hybridomas producing monoclonal antibodies specific for the e glycoprotein of st. louis encephalitis (sle) virus, strain msi-7, have been isolated. serologic reactivities were initially determined by cross-reactivity indirect immunofluorescence assays using 22 strains of sle virus and 8 other related flaviviruses. four groups demonstrating type-, subcomplex-, supercomplex-, and group-specific reactivity patterns were identified. analysis of hemagglutination-inhibition (hi) and virus n ...19836192585
elucidation of the topography and determination of the protective epitopes on the e glycoprotein of saint louis encephalitis virus by passive transfer with monoclonal antibodies.we have identified and characterized eight antigenic epitopes on the 53,000 dalton envelope (e) glycoprotein of saint louis encephalitis (sle) virus by using monoclonal antibodies. one of these epitopes (e-1c) encoded for the type-specific biologic functions of hemagglutination (ha) and neutralization (n). injection of 50 ng of anti-e-1c antibody protected the majority of mice from peripheral challenge with 100 i.p. ld50 of sle virus. similar levels of protection with antibodies specific for oth ...19846198396
variation in virulence for mice and rhesus monkeys among st. louis encephalitis virus strains of different origin.the virulence characteristics of 67 strains of st. louis encephalitis (sle) virus isolated from various sources in north, middle, and south america were compared in mice and rhesus monkeys. each virus strain was titrated in mice exactly 21 days old and virulence was expressed as the ratio of intracerebral (ic)/intraperitoneal (ip) ld50. virus strains fell into three groups: 1) high virulence (ic/ip ld50 ratio approximately 1.0); 2) intermediate virulence (variable mortality over a wide dose rang ...19806254384
isolation of st. louis encephalitis virus from a patient in belém, brazil.st. louis encephalitis (sle) virus was isolated from a 21-year-old female hospitalized on 4 october 1978 in belém, brazil. symptomatology on admission included fever, chills, severe headache, abdominal pain, myalgia, arthralgia and jaundice. sle virus was isolated from her blood drawn on the 8th day of illness and subsequent seroconversion was documented. serological tests showed the isolate to be closely related to the belém prototype of sle virus but distinct from other flaviviruses tested. th ...19816259956
variation among strains of st. louis encephalitis virus: basis for a genetic, pathogenetic, and epidemiologic classification. 19806261645
transovarial transmission of st. louis encephalitis virus by culex pipiens complex mosquitoes.experiments were conducted to determine whether transovarial transmission (tot) of st. louis encephalitis (sle) virus occurs in culex pipiens complex mosquitoes, the principal vectors of sle virus in the central-eastern united states. in 1978, field-collected mosquitoes from memphis, tennessee, and mcleansboro, illinois, were used; during 1979, colonized mosquitoes from chicago, illinois, and memphis, tennessee, were used. mosquitoes were infected by feeding on viremic chicks inoculated with an ...19816266266
genetic heterogeneity among saint louis encephalitis virus isolates of different geographic origin. 19816270878
[use of the simple radial hemolysis technic for the detection of antibodies to various flaviviruses]. 19826289389
winter survival of blood-fed and nonblood-fed culex pipiens l.comparisons were made between groups of culex pipiens l. with different physiologic histories to test their ability to sucessfully overwinter under field conditions. on 14 december 1978, each group of mosquitoes was marked with a distinctive fluorescent dust and released inside an abandoned ammunition bunker at fort washington, maryland. to insure that dead mosquitoes could be dissected and information obtained on their ovarian development, a sample of females from each group was also released i ...19826289686
comparative arboviral susceptibility of female culex tarsalis (diptera: culicidae) collected in co2-baited traps and reared from field-collected pupae. 19836298431
mode of entry of a neurotropic arbovirus into the central nervous system. reinvestigation of an old controversy.the mechanism by which neurotropic arboviruses gain access to the central nervous system remains uncertain, although it is generally assumed that viremic infection results in growth across or passive diffusion through brain capillaries. in contrast to the natural reservoir hosts of these arboviruses, clinical hosts (e.g., horses, humans) have viremias of very brief duration and low magnitude. we investigated the question of neuroinvasion in 5- to 6-week-old syrian hamsters infected with st. loui ...19836300550
comparative vector competence of culex tarsalis and culex quinquefasciatus from the coachella, imperial, and san joaquin valleys of california for st. louis encephalitis virus.st. louis encephalitis (sle) virus has continued to be active in the colorado desert region of southern california (coachella and imperial valleys) since 1973, while it has virtually disappeared from the sacramento and san joaquin valleys of central california. consequently, comparative vector competence studies were undertaken from 1978 to 1981 to evaluate the susceptibility of populations of culex quinquefasciatus and culex tarsalis from the san joaquin and coachella/imperial valleys to oral i ...19836301301
comparison of biological properties of st. louis encephalitis and rio bravo viruses.st. louis encephalitis (sle) virus, an arbovirus, and rio bravo (rb) virus, a non-arthropod-borne virus, are flaviviruses which cross-react in neutralization tests. several of their biological properties were compared. viral growth curves revealed that greater than 99% of infectious sle (parton) virus remained cell-associated in vero cells but was released slowly into the medium of infected bhk-21 cells. in contrast, rb (m-64) virus was released upon maturation into the fluids of vero and bhk-21 ...19836305222
serologic evidence of natural togavirus infections in panamanian sloths and other vertebrates.plasmas of sloths and other central panamanian wild vertebrates were tested for plaque-reduction neutralizing (prn) antibodies against four flaviviruses and one alpha-virus. forty percent of 97 two-toed sloths, choloepus hoffmanni, and 8% of 168 three-toed sloths, bradypus variegatus, were specifically positive against st. louis encephalitis (sle) virus. the prevalence of antibody against sle virus was considerably higher in sloths than in any other group of wild vertebrates tested, including bi ...19836309027
the house sparrow (passer domesticus) as a sentinel for st. louis encephalitis virus.birds are the primary hosts for st. louis encephalitis (sle) virus in most of north america. because the increased prevalence of antibody in house sparrows (passer domesticus) has been related to human cases, this species has been frequently used as a sentinel of sle virus activity in urban areas. this study investigated the susceptibility of house sparrows to two strains of sle virus, measured antibody profiles, and evaluated the use of house sparrows in an urban surveillance system. house spar ...19836312819
variation in infectivity of saint louis encephalitis viral strains for culex pipiens quinquefasciatus (diptera: culicidae). 19836315940
serologic evidence for widespread infection with la crosse and st. louis encephalitis viruses in the indiana human population.the vast under-reporting of la crosse virus and st. louis encephalitis virus infections in indiana residents was evident when numerous inapparent infections were detected retrospectively using serum dilution neutralization analyses of serum obtained in november 1978-april 1979 from 10,208 persons (0.2% of the state's population). an antibody prevalence rate of 3.6% to st. louis encephalitis virus was detected in the sample population as a whole, with rates as high as 13.2% for residents of indiv ...19846328975
immunoglobulin m antibody capture enzyme-linked immunosorbent assay for diagnosis of st. louis encephalitis.sera from patients with st. louis encephalitis were tested with an immunoglobulin m (igm) antibody capture enzyme immunoassay (mac elisa). the assay used five reagents: antihuman igm, test serum, sucrose-acetone-extracted mouse brain antigen, broadly cross-reactive flavivirus monoclonal antibody conjugated to alkaline phosphatase, and substrate (p-nitrophenyl phosphate). mac elisa endpoint titers correlated (r = 0.893) with the absorbance value of a 1:100 dilution of patient serum. significant ( ...19846386882
arthropod-borne virus infections of the central nervous system.arthropod-borne viruses (arboviruses) are an important cause of meningoencephalitis in north america. this article considers the common features of the four major cns arbovirus infections in this country and gives detailed descriptions of the individual virus infections.19846503938
reservoir of st. louis encephalitis virus in ohio bats.inoculation of the big brown bat (eptesicus fuscus) with a small dose of a st. louis encephalitis (sle) virus strain isolated in ohio indicated that the big brown bat was susceptible to infection. the virus was maintained in the bats through hibernation (70 days), and the bats developed a viremia within 4 days of arousal from hibernation (105 days after inoculation). a field survey of 390 big brown bats and little brown bats (myotis lucifugus) conducted in 5 regions of ohio during 1979 to 1981 r ...19836638648
experimental transovarial transmission of st. louis encephalitis virus by culex and aedes mosquitoes.colonized and field-collected female culex tarsalis, infected with st. louis encephalitis, (sle) virus by intrathoracic inoculation or by feeding on a viremic host, transmitted virus to their f1 adult and/or larval progeny when reared at 18(+/- 1) degree c but not when reared at 27(+/- 1) degrees c. the minimal infection rates (mir) for different populations of cx. tarsalis ranged from 1:32 to less than 1:250 (mean = 1:121) for larval progeny and from 1:32 to less than 1:1, 989 (mean = 1:1,571) ...19846696174
experimental st. louis encephalitis virus infection of sloths and cormorants.experimental infection of 11 bradypus variegatus and choloepus hoffmanni sloths with st. louis encephalitis (sle) virus produced detectable viremias of seven to 27 (median 13) days duration and maximum titers of 2.7 to 6.5 (median 5.1) log10 median suckling mouse intracranial lethal doses (smicld50) per ml. experimental sle viremia onset was delayed and maximum titer depressed in two sloths concurrently infected with naturally acquired viruses. sle viremias in four experimentally inoculated corm ...19836881434
visceral target organs in systemic st. louis encephalitis virus infection of hamsters. 19826891341
antigenuria in st. louis encephalitis.patients with st. louis encephalitis may have urinary tract symptoms when they develop manifestations related to involvement of the central nervous system. during 1976, 12 patients with st. louis encephalitis were studied for the presence of antigenuria, and compared to controls. although virus isolation attempts were negative indirect immunofluorescence, electron microscopy, and immune electron microscopy demonstrated the presence of viral antigen in urine. further study of antigenuria in st. l ...19806989277
antibody-mediated infection of macrophages and macrophage-like cell lines with 17d-yellow fever virus.the 17d vaccine strain of yellow fever virus (17d-yf) produces a safe human arboviral infection that can provide antisera of well-defined specificity under chronologically defined conditions. we studied 17d-yf growth in human peripheral blood macrophages and in two continuous fc receptor-bearing, macrophage-like cell lines, p388d1 of mouse origin and u937 of human origin. cells were infected with virus in the presence or absence of antibody to 17d-yf and to two related flaviviruses, st. louis en ...19817299376
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