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[differences in the white blood picture and blood glucose concentration of fed and starving spiny mice (acomys cahirinus, desmarest, 1819)]. 19695346728
helminthic infection of cairo spiny mouse. acomys cahirinus (e. geoffroy, st. hilaire, 1803) in u.a.r. 19695393691
studies in spiny mice (acomys cahirinus): metabolic state and pancreatic insulin release in vitro. 19695407070
the kidney of spiny mice (acomys cahirinus): electron microscopy of glomerular changes associated with ageing and tubular glycogen accumulation during hyperglycemia. 19705432358
insulin of spiny mice (acomys cahirinus)--partial characterization and evidence for two insulins. 19715540066
[obesity and diabetes mellitus in acomys cahirinus]. 19675583112
[the implantation time and the effect of lactation on it in acomys cahirinus dimidiatus]. 19675583113
[on the cerebralization of the nest-escaping acomys (cahirinus) minous (bate, 1906) in comparison with the nest-dwelling (albino mouse, apodemus sylvaticus (linnaeus, 1758) and albino rat). ii. morphology and allometry of postnatal brain development of acomys (cahirinus) minous, of the albino mouse, and of the albino rat]. 19685719048
[the myelogenesis of a nidifugious type (acomys (cahirinus) minous, bate 1906) in comparison to a nidicolous type (albino mouse)]. 19676053711
acanthocephala of the genus moniliformis from rodents of egypt with the description of a new species from the egyptian spiny mouse (acomys cahirinus). 19676066757
response of hepatic fructokinase to long-term sucrose diets and diabetes in spiny mice, albino mice and rats.the activity of hepatic fructokinase increased about 2-fold in desert-derived spiny mice (acomys cahirinus) and laboratory bred albino mice and rats, maintained on a 50% sucrose diet for 3 months. the role of fructose as the specific inducer was apparent, as 25% fructose diet produced activity increases similar to those of sucrose in contrast to 25% glucose diet. the activity of hexokinase was not affected by the sucrose diet, that of glucokinase rose marginally but those of pyruvate kinase and ...19846088170
perinatal development of the lung in rat and spiny mouse: its relation to altricial and precocial timing of birth.rat and spiny mouse (acomys cahirinus) are closely related murinoid species that represent altricial (rat) and precocial (spiny mouse) modes of development. the late intrauterine developmental stages of the spiny mouse therefore seem comparable to the early extrauterine developmental stages of the rat. to elucidate the question to what extent the development of the lung is related to the developmental timing of birth, we have studied some enzymes involved in the de novo synthesis of phosphatidyl ...19846326867
enzymatic and metabolic responses to affluent diet of two diabetes-prone species of spiny mice: acomys cahirinus and acomys russatus.the adaptive responses to sucrose and fat diets were investigated in two species of spiny mice, acomys russatus and acomys cahirinus, in relation to their propensity to develop diabetic-like symptoms. a russatus gained weight pronouncedly, both on regular and fat-rich seed diet, did not exhibit hyperglycemia or hyperlipidemia but had highly increased hepatic triglyceride content in association with high levels of circulating free fatty acids and incidence of ketonuria in 10 of 41 animals. on the ...19836360745
sucrose diet induced enzymatic and hormonal responses affecting carbohydrate, lipid and energy metabolism in two species differing in insulin availability: spiny and ob/ob mice.the low-insulin responding spiny mice (acomys cahirinus), maintained on a 50% sucrose diet vs isocaloric regular diet, responded with an impressive increase in the activity of hepatic enzymes of glycolysis and lipogenesis and in hyperlipidemia. there was no hyperinsulinemia or hyperglycemia and spiny mice did not gain weight on sucrose due to loss of adipose tissue. serum t3 levels rose 1.8 fold and the activity of the hepatic mitochondrial fad-glycerol-3-phosphate oxidase became induced 2.6 fol ...19846370752
paternal behavior in the spiny mouse (acomys cahirinus).the responsiveness of adult male spiny mice (acomys cahirinus) to both their own and alien precocial young was investigated. paternal behavior was manifested primarily by the males huddling with their offspring and the coordination of pup attendance between adult males and females. with less than 2 days exposure to their own neonates, males were found to discriminate between their own and alien young. experience plays an important role in the development of paternal behavior in spiny mice. males ...19846487216
chromosomal phylogeny of muridae: a study of 10 genera.the karyotypes of 10 different species of the family muridae (acomys airensis, arvicanthis niloticus, hylomyscus stella, malacomys longipes, mastomys huberti, myomys daltoni, mus musculus, rattus norvegicus, thamnomys gazellae, and uranomys ruddi) are compared by different banding techniques. from a reconstruction of the presumed ancestral karyotype of the muridae the sequence of the various rearrangements leading to the present karyotypes is proposed in order to determine their phylogenetic rel ...19836617265
archicortex and neocortex in the precocial murid acomys cahirinus. a comparison with two altricial species: mus musculus and rattus norvegicus.a morphological analysis of some structures of the archicortex and neocortex was performed in the acomys cahirinus (spiny mouse), the only precocial murid. the data obtained indicate that the spiny mouse brain is an interesting case of a largely developed hippocampus with respect to the neocortex when compared to the brains of the mouse and rat. the precocious pups of the spiny mouse present the peculiarity among murids of an early olfactory imprinting.19836668122
hippocampal maturation in the precocial murid rodent acomys cahirinus.growth rates in the dentate gyrus and hippocampus proper of the precocial murid acomys cahirinus were examined by measuring age-related changes in laminar volume in 0-, 10-, 20-, and 60-day postpartum animals. a biphasic course of maturation was observed in both structures, with rapid expansion occurring in the first 10 postnatal days and more gradual growth thereafter. this pattern of growth resembles those reported for newborn altricial murids such as the laboratory mouse and rat. however, due ...19846713169
brain acetylcholinesterase and its molecular forms in a precocial murid, acomys cahirinus, and rat during post-natal development.brain acetylcholinesterase (ache) and its molecular forms of a precocial murid, acomys cahirinus, characterized by a large hippocampus, were measured during post-natal development and compared with rat. the activity of soluble ache in acomys increased slightly up to 4 weeks after birth. the total ache activity increased somewhat more but, in rats, this increase was still greater. three main molecular forms of ache were separated by 7.5% polyacrylamide gel electrophoresis. their close similarity ...19846720191
olfactory bulb maturation in acomys cahirinus: is neural growth similar in precocial and altricial murids?olfactory bulb maturation was assessed in the precocial murid acomys cahirinus by quantifying developmental changes in laminar volume and glomerular and mitral cell size. at the time of birth (38 days postconception), the acomys bulb is in a developmental state similar to that of altricial murids of the same gestational age. rapid growth occurs in acomys during the first 10 postnatal days with more gradual changes occurring thereafter. altricial murids also exhibit accelerated bulb development i ...19836871728
delayed or biphasic glucose-induced insulin secretion of pancreatic islets isolated from spiny mice (acomys cahirinus) : relation to age of animals.the dynamics of insulin release from spiny mouse perifused pancreatic islets was investigated. in agreement with earlier studies we found no initial (0-10 min) insulin secretion in response to glucose in islets prepared from mice up to 35 weeks of age. the islets of animals older than 40 weeks, however, were characterized by greater insulin content, and a restored typical biphasic insulin secretion profile. the results suggest that immediate glucose response is modified by environmental or other ...19806989661
accumulation of pancreas-specific products during organogenesis of acomys cahirinus. 19806997134
comparison of insulin secretion by the isolated perfused pancreas and perifused islets of the spiny mouse (acomys cahirinus).the dynamics of glucose-stimulated insulin release were studied in the perfused pancreas and in isolated perifused islets of spiny mice. the pattern of insulin release induced by an increase of the glucose concentration from 2.8 mm to 16.7 mm was different in the two preparations. in the perfused pancreas there was an early insulin release contrasting with an absence of the early response in isolated islets. the later insulin release response (5 min to 30 min) was present and similar in both pre ...19817020305
[pyroantimonate-bound cations in the beta-cells of spiny mice pancreas (acomys cahirinus)]. 19817032701
intermediary metabolism during the development of obesity and diabetes in the desert rodent acomys cahirinus.the spiny mouse acomys cahirinus, which exhibits beta-cell hyperplasia but low insulin secretion in captivity responded with hyperlipidemia without obesity or diabetes on a sucrose diet and became obese, and glucose-intolerant on a diet of fat-rich seeds. a three-month sucrose diet induced a marked rise in the activity of regulatory enzymes of glycolysis and lipogenesis in the liver but not in adipose tissue. there was also increased energy waste on this diet evident from a three-fold rise in th ...19827118367
the oestrous cycle of the spiny mouse (acomys cahirinus).the oestrous cycle of the spiny mouse (acomys cahirinus), as determined by vaginal smears, is 11.1 +/- 1.9 (s.d.) days (n = 110). the vaginal smears show cell patterns similar to those seen in the rat, but secretion of mucus is greater than in the rat. the average age at vaginal opening is 45 +/- 2.77 (s.e.m.) days, but the first litter (sired by litter mates) did not occur until 103 +/- 4.04 (s.e.m.) days. the decidual response to uterine trauma indicates tha there is an active luteal phase. th ...19817193735
the response of the egyptian spiny mouse (acomys cahirinus) and two other species of commensal rodents to anticoagulant rodenticides.the response of acomys cahirinus to three anticoagulant rodenticides was investigated in the laboratory. in contrast to the other commensal rodents rattus rattus and r. norvegicus, this species appears to be naturally very resistant to warfarin, difenacoum and brodifacoum. it is considered unlikely that anticoagulant poisons would be effective in the field for the control of a. cahirinus.19817240734
experiential influences on the development of huddling preferences and "sibling" recognition in spiny mice.the role of experience in the development of huddling preferences and sibling recognition by spiny mouse (acomys cahirinus) weanlings was investigated. in the 1st experiment, pups separated from their littermates and fostered onto unfamiliar females (and their offspring) on the day of birth, day 10, or day 20, subsequently showed preferential huddling with their foster littermates. huddling by biological siblings was as infrequent as huddling by unrelated, unfamiliar agemates. the 2nd study reve ...19817250526
development of the adult pelage in normal and hormone-injected spiny mice (acomys cahirinus).the dorsal pelage of the adult egyptian spiny mouse (acomys cahirinus) consists primarily of coarse brittle spines which differ from those of the juvenile pelage. the development of the adult pelage in juvenile spiny mice was examined in normal and estradiol- or testosterone-injected animals. females complete the development of their adult pelage significantly faster than males. both estradiol and testosterone injections speed pelage development in males. testosterone causes a significant delay ...19817338723
maternal behavior and the milk ejection reflex in a precocial murid (acomys cahirinus). 19807362595
interaction between acari ectoparasites and rodents in suez governorate, egypt.from the medical point of view, the relation between man and rodents comes in the priority. some rodent populations are wild but others are commensal and live in close association with man. they steal his food and conveying many zoonotic diseases. their arthropod ectoparasites play an important role in conveying or transmitting these zoonotic diseases. several disorders and diseases of man are tick borne relapsing fever, rocky mountain spotted fever, lyme disease, and many others. besides numero ...19957665934
biotransformation in egyptian spiny mouse acomys cahirinus.the activities of several representative biotransformation enzymes were determined in male and female spiny mouse tissues. cytochrome p450 monooxygenase activity toward benzo(a)pyrene was significantly greater in female spiny mouse intestine than in males. activity toward benzphetamine in both sexes was high in the liver, with little activity in the kidney and intestine. sulfotransferase activity was high in kidney and intestine of female spiny mice but undetectable in the same tissues in males. ...19957749597
organ-to-body weight ratio in the egyptian spiny mouse acomys cahirinus. 19947933979
ultrastructure of kolmer's crystalloid in the pinealocytes of the common spiny mouse (acomys cahirinus dimidiatus).light- and electron-microscopical observations revealed a rod-like inclusion body in the pinealocytes of the common spiny mouse (acomys cahirinus dimidiatus). ultrastructurally, the body is composed of a varying number of tubes whose wall consists of thin filaments aligned in helical arrangement. the inner and outer surface of the wall is covered with ribosome-like granules. based on a morphological analysis it is concluded that the body described in the present investigation is identical with k ...19938269483
daily rhythms of body temperature in acomys russatus: the response to chemical signals released by acomys cahirinus.two species of spiny mice of the genus acomys--the golden spiny a. russatus and the common spiny a. cahirinus--are sympatric in the arid and hot parts of the rift valley in israel. the coexistence of these two species is due to exclusion of a. russatus mice by a. cahirinus mice from nocturnal activity. the aim of this research was to study if odor signals released by a. cahirinus mice can play a role in the exclusion of a. russatus mice. a. russatus mice with an implanted transmitter recording b ...19938319316
larval occurrence of hydatigera taeniaeformis batsch (1786) (cestoda: taeniidae) in the liver of wild rodents in egypt.hydatigera taeniaeformis batsch (1786) was found in the liver of six species of egyptian wild rodents. wanas et al., (1990) found the total incidence of this larval stage to be 20.0% among cestode infection. it was found in (40.9%) rattus norvegicus; (33.3%) gerbillus gerbillus; (26.8%) rattus rattus; (25.0%) mus musculus; (16.6%) acomys cahirinus; and (7.2%) arvicanthis niloticus. the cysts of hydatigera taenioformis was always occupying the marginal surfaces of both right and left lobes and so ...19938376855
stability of preference for odors after short-term exposure in young spiny mice.the stability of olfactory preferences for artificial odors was studied in young spiny mouse pups (acomys cahirinus). subjects aged between 2 and 20 days were exposed to the odor of either cinnamon or cumin for 1.5 hr. the durability of preferences for the familiar versus novel odor was subsequently monitored in a three-choice preference test. the results suggest the existence of a sensitive phase for learning odor characteristics, through simple exposure, between days 2 and 18 of the pups' post ...19938440404
the cairo spiny mouse acomys cahirinus shows a strong affinity to the mongolian gerbil meriones unguiculatus.the classification of the african spiny mice (genus acomys) within the muridae family of rodents has been fraught with controversy. morphological data suggest a close affinity between this group and true old world mice of the genus mus. however, the combined results of immunological, biochemical, and dna melting studies suggest that spiny mice should not even be considered as members of the murinae subfamily. to further elucidate the position of the spiny mice within the rodent phylogenetic tree ...19968583903
development and consequences of insulin resistance: lessons from animals with hyperinsulinaemia.studies involving genetically and nutritionally induced diabetes in animals indicate that early hyperinsulinaemia is the causative factor of tissue insulin resistance, leading to compensatory insulin oversecretion and pancreatic beta-cell dysfunction. the models for this syndrome, which occurs in association with obesity (thus termed "diabesity" here), concern either species with a sturdy pancreas, capable of long-lasting oversecretion, or those with labile beta cells which cannot sustain the in ...19968792092
respiratory rhythm generation in a precocial rodent in vitro preparation.in vitro preparations for studying the neural control of respiration consisting of brainstem and spinal cord regions isolated from the newborn (po-p1) precocial rodent, acomys cahirinus (spiny mouse) are described. spiny mice have a longer gestation period (39 days) than laboratory rats (22 days) and mice (20 days) and thus are born in a considerably more mature state. we sought to determine if in vitro preparations isolated from spiny mice would spontaneously generate a respiratory motor patter ...19968833542
effect of passage of babesia ovis in the gerbil (acomys cahirinus) on the course of infection in splenectomized lambs.splenectomized gerbils (acomys cahirinus) have been found to be susceptible to babesia ovis applied via blood inoculation, whereas intact gerbils were not infected. blood from splenectomized latently infected gerbils caused infection in a splenectomized lamb. intact acomys cahirinus gerbils did not become infected by b. ovis, and all captured rodents in an enzootic area, intact and splenectomized, were found to be negative for b. ovis. it can thus be concluded that acomys cahirinus does not serv ...19968916410
the chromosome complement of acomys spp. (rodentia, muridae) from oursi, burkina faso--the ancestral karyotype of the cahirinus-dimidiatus group?we present here data on chromosome banding analysis (r- and c-bands) of acomys sp. (rodentia, muridae) from oursi, burkina faso, characterized by 2n = fn = 68 and comparison of its banding patterns with those of acomys dimidiatus from saudi arabia (2n = 38, fn = 70), studied previously. the study revealed complete homology between acrocentric chromosomes of acomys sp. and chromosome arms of 16 pairs of metacentric and two pairs of acrocentric chromosomes of a. dimidiatus. in addition to monobrac ...19968939364
a new coccidian from acomys cahirinus desmarest, 1819, from evolution canyon, lower nahal oren, mount carmel, israel.in 1994, fresh fecal samples were collected and examined for coccidian parasites from 43 spiny mice (acomys cahirinus) and from 60 wood mice (apodemus mystacinus). the 2 genera of rodents inhabit an area in lower nahal oren. mount carmel, israel, known as evolution canyon, which consists of opposite-facing slopes that are geologically identical, but micro-climatically very different. acomys cahirinus is found primarily on the warmer and drier south-facing slope (sfs), whereas a. mystacinus prima ...19979105310
histology and enzymatic activity in the postnatal development of limb muscles in rodents.the present work examines how increases in spontaneous motor capabilities during postnatal development are reflected in enzymatic activity and the histology of hindlimb muscles of the dormouse (eliomys melanurus), the jird (meriones tristrami), the vole (microtus socialis), and the spiny mouse (acomys cahirinus). the precocial neonate of the spiny mouse had the most advanced developmental state of young myofibers with striations as early as 1 week after delivery. at the same age, the altricial n ...19989523911
intrageneric phylogeny of acomys (rodentia, muridae) using mitochondrial gene cytochrome b.this paper investigates interspecies relationships within the genus acomys (spiny mice) by analyzing entire mitochondrial cytochrome b gene (1141 bp). this gene provides strong phylogenetic signal, as shown by high support of the topology obtained (bootstrap value and rna support number). the phylogeny is congruent with inferences from allozymes for the species considered. controversial taxonomy of acomys cahirinus, dimidiatus, airensis, and ignitus is clarified, with their specific ranks confir ...19989668005
photoperiodic responses of four wild-trapped desert rodent species.the purpose of this study was to examine the effect of the photoperiod on reproductive status and body and lipid masses in four egyptian desert rodent species (dipodillus dasyurus, acomys cahirinus, gerbillus andersoni, and gerbillus pyramidum). adult males and females were housed in long days for 11 wk. at that time, one-half of the animals were killed and the remaining animals were moved to short days (sds) for 11 wk. some individuals of gerbillus andersoni and gerbillus pyramidum had access t ...19989843891
analysis of some biophysical and biochemical parameters of long bones of spiny mouse (acomys cahirinus) in its life cycle. 199910353008
differential behavioural and hormonal responses of voles and spiny mice to owl calls.rodents usually respond to the presence of owls by reducing overall activity, in particular foraging. in this study, a playback of recorded tawny owl, strix aluco, calls was sufficient to induce a marked effect in the social (gunther's) vole, microtus socialis. some of the voles exposed to owl calls reduced their activity ('freeze' pattern) unlike control voles exposed to a human voice. other voles, however, dashed around the cage ('flee' pattern). owl calls also increased corticosterone levels ...199910564611
seasonal thermogenic acclimation of diurnally and nocturnally active desert spiny mice.diurnally active golden spiny mice (acomys russatus) and nocturnal common spiny mice (acomys cahirinus) coexist in hot rocky deserts of israel. diurnal and nocturnal activities expose these species to different climatic conditions. nonshivering thermogenesis (nst) capacity of individuals of both species immediately upon removal from the field exhibited seasonal changes, with no significant interspecific difference. colony-reared mice of either species transferred in the laboratory from long to s ...200610685905
overnutrition in spiny mice (acomys cahirinus): beta-cell expansion leading to rupture and overt diabetes on fat-rich diet and protective energy-wasting elevation in thyroid hormone on sucrose-rich diet.previous studies: the investigation of diabetes propensity in spiny mice, performed in geneva and jerusalem colonies, is reviewed. spiny mice live in semi-desert regions of the eastern mediterranean countries. those transferred to geneva in the 1950s were maintained on a rodent diet supplemented by fat-rich seeds. they became obese, exhibited pancreatic islet hyperplasia and hypertrophy. low insulin secretion response was characteristic of this species, despite ample pancreatic content of insuli ...200010751749
intestinal helminths of spiny mice (acomys cahirinus dimidiatus) from st katherine's protectorate in the sinai, egypt.spiny mice, acomys cahirinus dimidiatus, inhabiting the wadis close to st katherine in the mountains of the sinai peninsula, were trapped and their helminth parasites were studied. sixty one mice provided faeces for analysis and 27 were killed and autopsied. six species of helminths were recorded (the spirurid nematodes, protospirura muricola (74.1%) and mastophorus muris (11.1%), the oxyuroid nematodes, dentostomella kuntzi (59.3%), aspiculuris africana (3.7%), and syphacia minuta (3.7%) and th ...200010831051
notes on mites of the family myobiidae (acari: prostigmata) parasitising rodents (mammalia: rodentia) in iran.six mite species of the family myobiidae, radfordia (austromyobia)persica sp. n., radfordia (austromyobia) merioni bochkov, dubinina et chirov, 1990, radfordia (radfordia) acomys fain et lukoschus, 1977, radfordia (radfordia) affinis (poppe, 1896), radfordia (graphiurobia) dyromys fain et lukoschus, 1973, and myobia (myobia) murismusculi (schrank, 1781) were found in iran on the rodents gerbillus cheesmani thomas, meriones libycus lichtenstein, acomys cahirinus (desmarest), alus musculus l., dry ...200010833020
temporal partitioning among diurnally and nocturnally active desert spiny mice: energy and water turnover costs.nocturnal acomys cahirinus and diurnally active a. russatus coexist in hot rocky deserts. diurnal and nocturnal activity exposes them to different climatic challenges. a doubly-labelled water field study revealed no significant differences in water turnover between the species at all seasons, reflecting the adaptations of a. russatus to water conservation. in summers the energy expenditure of a. russatus tended to be higher than that of a. cahirinus. energy requirements of a. cahirinus in winter ...200111163930
morphology, topography and cytoarchitectonics of the otic ganglion in egyptian spiny mouse (acomys cahirinus, desmarest).using the thiocholine method of koelle and friedenwald and histological techniques, the otic ganglion in egyptian spiny mouse (acomys cahirinus, desmarest) was studied. the ganglion was found to be a single oval cluster of neurocytes, situated at the medial and posterior surface of the mandibular nerve just above the maxillary artery. the ganglion is composed of typical ganglionic neurons in compact arrangement without a thick connective-tissue capsule.200111234700
audiograms of five species of rodents: implications for the evolution of hearing and the perception of pitch.behavioral audiograms were determined for five species of rodents: groundhog (marmota monax), chipmunk (tamias striatus), darwin's leaf-eared mouse (phyllotis darwinii), golden hamster (mesocricetus auratus), and egyptian spiny mouse (acomys cahirinus). the high-frequency hearing of these animals was found to vary inversely with interaural distance, a typical mammalian pattern. with regard to low-frequency hearing, the animals fell into two groups: those with extended low-frequency hearing (chip ...200111470193
[structural characteristics of certain rodents spines (rodentia: myomorpha, hystricomorpha)].the architectonics of spines and hair was studied in neacomys spinosus, arvicanthis somalicus, leopoldamys sabanus, l. edwardsi, maxomys moi, m. surifer, niviventer fulvescens, n. confucianus, n. cremoriventer, acomys cahirinus, a. somalica, hystrix indica, h. cristata, atherurus macrourus, erethizon dorsatum, proechimys steerei, and lonchotrix emiliae. the presence of a dorsal longitudinal furrow covered by a modified cuticle is a common structural feature of spines in all studied species excep ...201611525125
albert renold memorial lecture: molecular background of nutritionally induced insulin resistance leading to type 2 diabetes--from animal models to humans.albert renold strived to gain insight into the abnormalities of human diabetes by defining the pathophysiology of the disease peculiar to a given animal. he investigated the israeli desert-derived spiny mice (acomys cahirinus), which became obese on fat-rich seed diet. after a few months hyperplasia and hypertrophy of beta-cells occurred leading to a sudden rupture, insulin loss and ketosis. spiny mice were low insulin responders, which is probably a characteristic of certain desert animals, pro ...200111795838
dietary-dependent cross-species similarities in maternal chemical cues.acomys cahirinus pups preferred chemical cues from conspecific lactating females maintained on the maternal diet as compared to such cues from females fed an unfamiliar diet. likewise, chemical cues from maternal diet mus musculus were preferred over those from unfamiliar diet conspecific females. thus, the production of maternal chemical stimuli may be basically similar in acomys and mus, with maternal diet being more critical than genetically programmed species-specific characteristics in dete ...197711803674
comparative non-shivering thermogenesis in adjacent populations of the common spiny mouse (acomys cahirinus) from opposite slopes: the effects of increasing salinity.we compared non-shivering thermogenesis between two adjacent populations of the common spiny mouse acomys cahirinus from different habitats, in relation to increasing salinity. individuals were captured from the north- and south-facing slopes of the same valley, that represent "mediterranean" and "desert" habitats, respectively. we hypothesized that the two populations of mice would differ in their thermoregulatory capacities, reflecting their need to cope with the environmental stress in each h ...200211824399
the effects of season and dietary salt content on body temperature daily rhythms of common spiny mice from different micro-habitats.we compared body temperature (t(b)) daily rhythms in two populations of common spiny mice, acomys cahirinus, during summer and winter months in relation to increasing dietary salt content. mice were collected from the north and south facing slopes (nfs and sfs) of the same valley, that are exhibiting mesic and xeric habitats, respectively. during the summer, whilst mice were offered a water source containing 0.9% nacl, sfs individuals had t(b) peak values at 24:00, whereas nfs individuals had pe ...200212020645
the structure of the spiny mouse (acomys cahirinus) ovary during development.the study presents the structure of the ovaries of the spiny mouse (acomys cahirinus) during the first months of life. the ovaries in neonate females exhibit a large number of primordial and primary follicles, sometimes clustered in nests. the growing follicles were also observed within the ovary at that period. the first, early antral follicles appeared in the ovary during the second week of life. in the group of 60-day old females, the structure of the ovaries was characterized by a significan ...200212056623
morphology, topography and cytoarchitectonics of the pterygopalatine ganglion in egyptian spiny mouse (acomys cahirinus, desmarest).using the thiocholine method of koelle and friedenwald and histological techniques the pterygopalatine ganglion in egyptian spiny mouse (acomys cahirinus, desmarest) was studied. the ganglion was found to be a single irregular cluster of neurocytes, situated on the medial surface of the maxillary nerve. the ganglion is composed of oval, elliptical and sometimes fusiform ganglionic neurones in compact arrangement without a thick connective-tissue capsule.200212164048
host specificity and foraging efficiency in blood-sucking parasite: feeding patterns of the flea parapulex chephrenis on two species of desert rodents.parasite species can adapt to ecological, behavioral, physiological and biochemical traits of a particular host species. the flea parapulex chephrenis occurs on the spiny mouse acomys cahirinus, but does not occur on a co-existing gerbil, gerbillus dasyurus. to test the hypothesis that the host species affects feeding parameters of a host-specific flea, we studied the feeding rate, rate of blood digestion and resistance to starvation of p. chephrenis when feeding on a. cahirinus and g. dasyurus. ...200312739133
a comparative study on cardiac ganglia in midday gerbil, egyptian spiny mouse, chinchilla laniger and pigeon.using the thiocholine method and histological techniques, the topography and morphology of cardiac ganglia in midday gerbil, egyptian spiny mouse, chinchilla laniger and pigeon were studied. the results demonstrated that cardiac ganglia in all investigated species are embedded in epicardial fat. they formed plexo-ganglionic structures. each of them composed of many ganglia (from seven up to 36) different in size and shape, and interconnected by fascicles of nerve fibres. comparative analysis sho ...200312823098
local variation in helminth burdens of egyptian spiny mice (acomys cahirinus dimidiatus) from ecologically similar sites: relationships with hormone concentrations and social behaviour.populations of egyptian spiny mice (acomys cahirinus dimidiatus) in a fragmented montane wadi system in the sinai showed significant differences in the abundance of gut helminths. differences in parasite load between populations were positively associated with measures of androgen activity but showed no significant relationship with glucocorticoid activity. social discrimination tests with adult males from different wadis showed that those from sites with greater helminth abundance were less lik ...200312895278
[intraspecific and intraindividual chromosomal polymorphism in acomys minous bate (mammalia--rodentia--muridae). cytological study of acomys minous male x acomys cahirinus female hybrids. the mechanism of centric fusions]. 196314096525
the behaviour of plasmodium berghei and plasmodium vinckei in the spiny mouse acomys cahirinus. 196114448536
rodents in open space adjust their behavioral response to the different risk levels during barn-owl attack.previous studies have revealed that the response of prey species to predatory risk comprised either freezing (when the prey remained immobile), or fleeing (when it ran frantically in order to remove itself from the vicinity of the predator). other studies, however, have suggested that the prey will adjust its behavior to risk level. the present study was designed to follow the attacks of a barn owl (tyto alba) on common spiny mice (acomys cahirinus) and social voles (microtus socialis guntherei) ...200314614781
human zoonotic cutaneous leishmaniasis and associated sand flies (diptera: psychodidae) in sheikh atiya village, southern sinai, egypt.zoonotic cutaneous leishmaniasis is endemic in sinai peninsula. human cases were recorded from the northern sinai, however little was known about the disease in southern sinai. during entomological surveys conducted southern sinai in summers of 1997-1999, a clinically confirmed zcl case was encountered for the first time in sheikh atiya village in june 1999. the parasite was isolated and identified as l. major using cellulose acetate electrophoresis. a total of 784 phlebotomine sand flies were c ...200314708854
differential energy costs of winter acclimatized common spiny mice acomys cahirinus from two adjacent habitats.the common spiny mouse acomys cahirinus, of ethiopian origin, has a widespread distribution across arid, semi-arid and mediterranean parts of the arabian sub-region. we compared the daily energy expenditure (dee), water turnover (wto) and sustained metabolic scope (susms=dee/resting metabolic rate) of two adjacent populations during the winter. mice were captured from north- and south- facing slopes (nfs and sfs) of the same valley, comprising mesic and xeric habitats, respectively. both dee and ...200415123215
anatomical and histological data on the ciliary ganglion in the egyptian spiny mouse (acomys cahirinus desmarest).the morphology and topography of the ciliary ganglion in the egyptian spiny mouse were studied with use of histochemical and histological techniques. the ciliary ganglion of the egyptian spiny mouse consisted of between 3 and 4 agglomerations of nerve cells. the largest was situated at the point where the ventral branch of the oculomotor nerve divides into two branches. the next two smaller aggregations were located on the superior and lateral surfaces of the optic nerve where it crossed the ocu ...200415478100
locomotor activity in common spiny mice (acomys cahirinuse): the effect of light and environmental complexity.rodents typically avoid illuminated and open areas, favoring dark or sheltered environments for activity. while previous studies focused on the effect of these environmental attributes on the level of activity, the present study tested whether the spatio-temporal structure of activity was also modified in illuminated compared with dark and complex compared with open arenas. for this, we tested common spiny mice (acomys cahirinus) in empty or stone-containing arenas with lights on or lights off.200415537426
the spiny mouse (acomys cahirinus) completes nephrogenesis before birth.the spiny mouse is relatively mature at birth. we hypothesized that like other organs, the kidney may be more developed in the spiny mouse at birth, than in other rodents. if nephrogenesis is complete before birth, the spiny mouse may provide an excellent model with which to study the effects of an altered intrauterine environment on renal development. due to its desert adaptation, the spiny mouse may have a reduced cortex-to-medulla ratio but an equivalent total nephron number to the c57/bl mou ...200515741606
energy costs of blood digestion in a host-specific haematophagous parasite.fleas consume and digest blood from their hosts. we hypothesized that the energy costs of digestion of blood by fleas is dependent on the host species. to test this hypothesis, we studied co2 emission, a measure of energy expenditure, during digestion of a blood meal taken by parapulex chephrenis from a preferred (acomys cahirinus) and a non-preferred (gerbillus dasyurus) host. we predicted that the energy cost of digestion would be lower for a. cahirinus blood than that for g. dasyurus. male an ...200515961735
sex-biased parasitism, seasonality and sexual size dimorphism in desert rodents.we investigated seasonality of gender differences in the patterns of flea infestation in nine rodent species to test if sex-biased parasitism in terms of mean abundance, species richness, prevalence and the level of aggregation (a) varies among hosts and between seasons, and (b) is linked to sexual size dimorphism. sexual size differences were significant in both summer and winter in acomys cahirinus, gerbillus pyramidum and meriones crassus, and in winter only in acomys russatus, gerbillus dasy ...200516025350
circadian activity rhythms in the spiny mouse, acomys cahirinus.circadian locomotor rhythms were examined in adult common spiny mice, acomys cahirinus. spiny mice demonstrated nocturnal activity, with onset of activity coinciding promptly with onset of darkness. re-entrainment to 6-h delays of the light-dark cycle was accomplished faster than to 6-h advances. access to running wheels yielded significant changes in period and duration of daily activity. novelty-induced wheel running had no effect on phase of activity rhythms. circadian responses to light at v ...200516176823
geographic variation in body size: the effects of ambient temperature and precipitation.latitudinal trends in body size have been explained as a response to temperature- or water-related factors, which are predictors of primary production. we used the first principal component calculated from three body parameters (weight, body length and the greatest length of the skull) of a sample of mammals from israel and sinai to determine those species that vary in size geographically, and whether such variation is related to annual rainfall, average minimum january temperature and average m ...200616525785
temporal variation in parasite infestation of a host individual: does a parasite-free host remain uninfested permanently?host individuals not infested by parasites at a given time are either permanently free from parasites or could be infested at other times. we studied temporal variation in the presence or absence of fleas (siphonaptera) on individual rodents of two species (gerbillus dasyurus and acomys cahirinus) and questioned if and how an individual rodent can change its infestation status temporally. change in infestation status by fleas over time was found in 45.5% of g. dasyurus and 35.9% of a. cahirinus. ...200616628454
spiny mice (acomys cahirinus) do not respond to thymus-independent type 2 antigens.analysis of the immune system of spiny mice (acomys cahirinus) has been limited. originally grouped with mus, acomys has recently been placed closer to meriones (gerbils). this study compared immunity in acomys, mus, and meriones. lymphocytes from all rodents examined proliferated in response to mitogen and superantigen stimulation. only mus t cells responded to anti-cd3 stimulation. acomys, like meriones, and mus that express xid, did not respond to thymus-independent type 2 antigens. flow cyto ...200616698082
nutritionally induced diabetes in desert rodents as models of type 2 diabetes: acomys cahirinus (spiny mice) and psammomys obesus (desert gerbil).the dietary effects of hyperglycemia increasingly result in type 2 diabetes in humans. two species, the spiny mice (acomys cahirinus) and the desert gerbil (psammomys obesus), which have different metabolic responses to such effects, are discussed. spiny mice exemplify a pathway that leads to diabetes without marked insulin resistance due to low supply of insulin on abundant nutrition, possibly characteristic of a desert animal. they respond with obesity and glucose intolerance, beta-cell hyperp ...200616804196
immunohistochemical localization of estrogen receptors eralpha and erbeta in the spiny mouse (acomys cahirinus) ovary during postnatal development.this study was designed to determine the expression pattern of estrogen receptor (er) subtypes in the acomys cahirinus ovarian cells during its postnatal development. immunohistochemical studies revealed the presence of eralpha and erbeta in germinal epithelium cells and interstitial tissue. both these er subtypes were also seen in granulosa cells and oocytes of growing follicles, however, the level of erbeta expression was higher in comparison with eralpha. in contrast to erbeta, eralpha protei ...200717180742
between-host phylogenetic distance and feeding efficiency in hematophagous ectoparasites: rodent fleas and a bat host.we hypothesized that a parasite exploits most effectively its principal host, less effectively a host that is phylogenetically close to its principal host, and least effectively a host that is phylogenetically distant from its principal host. we tested this hypothesis by quantifying the feeding efficiency of two flea species (parapulex chephrenis and xenopsylla ramesis) on two rodents, acomys cahirinus, the specific host of p. chephrenis, and meriones crassus, a preferred host of x. ramesis, and ...200717297629
topography of arterial circle of the brain in egyptian spiny mouse (acomys cahirinus, desmarest).using stained acryl latex-injected techniques, the arterial circle of the brain in acomys cahirinus desmarest was studied. results revealed an important individual variability of investigated structure. three morphological variants were found: (1) the lack of typical arterial circle--opened in front and the back side, (2) partial opened at the back side, (3) completely closed arterial circle. this finding is opposed to many species of mammals, including rodents, and especially laboratory mouse. ...200717371389
maternal creatine: does it reach the fetus and improve survival after an acute hypoxic episode in the spiny mouse (acomys cahirinus)?we hypothesized that elevating creatine in the maternal diet would reach fetal and placental tissues and improve fetal survival after acute hypoxia at birth.200818295173
the effects of sex, age and commensal way of life on levels of fecal glucocorticoid metabolites in spiny mice (acomys cahirinus).we studied levels of fecal glucocorticoid metabolites (gcm) in a social rodent - egyptian spiny mouse. as breeding adults are socially dominant over subadults, and adolescent males are driven away by the dominant males, we addressed the question whether animals within extended families are stressed differently depending upon their social category. in addition, we evaluated whether there are differences between non-commensal (outdoor) and commensal (adapted to human settlements) populations. conc ...200818586285
helminths collected from imported pet murids, with special reference to concomitant infection of the golden hamsters with three pinworm species of the genus syphacia (nematoda: oxyuridae).a total of 210 individuals of 13 species belonging to 4 subfamilies of muridae imported into japan as pets were examined; 5 species of syphacia (nematoda: oxyuridae), aspiculuris tetraptera (nematoda: heteroxynematidae), and rodentolepis nana (cestoidea: hymenolepididae) were collected. concurrent infection with 3 pinworm species, syphacia mesocriceti, syphacia stroma, and syphacia peromysci, was recorded for the first time in the golden hamster, mesocricetus auratus. syphacia mesocriceti was al ...200818605784
does acquired resistance of rodent hosts affect metabolic rate of fleas?we studied whether (a) previous infestation of a rodent host with fleas and (b) the reproductive effort of fleas affect the rate of co(2) emission in two flea species, host-specific parapulex chephrenis and host-opportunistic xenopsylla ramesis when feeding on their typical and atypical rodent hosts. we measured the rate of co(2) emission in preovipositing and ovipositing female fleas fed on either pristine or previously infested acomys cahirinus (typical host of p. chephrenis) and dipodillus da ...200919350621
burrowing: a sensitive behavioural assay, tested in five species of laboratory rodents.in the burrowing test, mice or rats spontaneously empty a tube filled with food pellets, gravel or other substances. the test is extremely simple to perform, the apparatus is inexpensive and readily constructed. it exploits a natural rodent behaviour, provides quantitative data under controlled laboratory conditions, and has proved extremely sensitive to prion disease in mice (mus musculus), cytokines in rats (rattus norvegicus), lipopolysaccharide in mice and rats, strain differences and brain ...200919373978
apparatus for collection of fecal samples from undisturbed spiny mice (acomys cahirinus) living in a complex social group.assessment of fecal glucocorticoid metabolites has become a widely used method for monitoring stress responses. because most small rodents are social animals whose physiologic parameters are affected by social stimuli, individual housing may compromise these data. nevertheless, housing rodents in families or social groups may be an important limitation to the experimental design. the challenge is to collect samples from individual rodents while avoiding stress-associated effects from the samplin ...200919383218
behavioural effects of near-term acute fetal hypoxia in a small precocial animal, the spiny mouse (acomys cahirinus).we have previously developed a model of near-term intra-uterine hypoxia producing significant neonatal mortality (37%) in a small laboratory animal - the spiny mouse - which has precocial offspring at birth. the aim of the present study was to determine if this insult resulted in the appearance of behavioural abnormalities in those offspring which survived the hypoxic delivery. behavioural tests assessed gait (using footprint patterns), motor coordination and balance on an accelerating rotarod, ...201019590246
detection of bartonella spp. in wild rodents in israel using hrm real-time pcr.the prevalence of bartonella spp. in wild rodents was studied in 19 geographical locations in israel. one hundred and twelve rodents belonging to five species (mus musculus, rattus rattus, microtus socialis, acomys cahirinus and apodemus sylvaticus) were included in the survey. in addition, 156 ectoparasites were collected from the rodents. spleen sample from each rodent and the ectoparasites were examined for the presence of bartonella dna using high resolution melt (hrm) real-time pcr. the met ...200919595521
neuroprotective properties of melatonin in a model of birth asphyxia in the spiny mouse (acomys cahirinus).birth asphyxia is associated with disturbed development of the neonatal brain. in this study, we determined if low-dose melatonin (0.1 mg/kg/day), administered to the mother over 7 days at the end of pregnancy, could protect against the effects of birth asphyxia in a precocial species - the spiny mouse (acomys cahirinus). at 37 days of gestation (term is 38-39 days), pups were subjected to birth asphyxia (7.5 min uterine ischemia) and compared to cesarean section-delivered controls. at 24 h of a ...200919684403
seasonal variation of infestation rate with lice, tick and mite among rodents in certain egyptian regions.four species of mites (ornithonyssus bacoti, haemolaelaps glusgowi, echinolaelaps echinolelaps & dermanyssus gallinae), two species of ticks (rhipicephalus sanguineus & hyalomma dromedarrii) and one species of lice (polyplax spinulose) were identified on rodents during 4 successive seasons (2005) trapped in five governorates (suez, menoufia, giza, damietta and beni-sewaf). the rodents were rattus norvegicus, rattus rattus alexandrinus, rattus rattus frugivourus, acomys cahirinus and mus musculus ...200919795768
neuropathology and functional deficits in a model of birth asphyxia in the precocial spiny mouse (acomys cahirinus).birth asphyxia can result in sensory impairment, learning and memory deficits without gross brain injury and severe motor deficits. we developed a model of birth asphyxia resulting in mild neurological injury and cognitive impairment using a long-gestation species with precocial fetal development. spiny mice (acomys cahirinus) underwent caesarean-section delivery or 7.5 min of asphyxia at 37 days gestational age (term is 39 days). brain histology was examined at 1 and 7 days of age, and behaviou ...200919851070
masking and temporal niche switches in spiny mice.activity patterns are the product of interactions between an internal circadian clock and direct responses to photic and nonphotic features of the environment that are said to "mask" the influence of that clock. evolutionary transitions between nocturnality and diurnality involve changes in mechanisms underlying both of these processes. here, the authors examined how masking influences activity patterns of golden spiny mice ( acomys russatus), which can be either nocturnal or diurnal, and common ...201020075300
spiny mice modulate eumelanin to pheomelanin ratio to achieve cryptic coloration in "evolution canyon," israel.coat coloration in mammals is an explicit adaptation through natural selection. camouflaging with the environment is the foremost evolutionary drive in explaining overall coloration. decades of enquiries on this topic have been limited to repetitive coat color measurements to correlate the morphs with background/habitat blending. this led to an overwhelming endorsement of concealing coloration as a local phenotypic adaptation in animals, primarily rodents to evade predators. however, most such s ...201020090935
the substructure of the suprachiasmatic nucleus: similarities between nocturnal and diurnal spiny mice.evolutionary transitions between nocturnal and diurnal patterns of adaptation to the day-night cycle must have involved fundamental changes in the neural mechanisms that coordinate the daily patterning of activity, but little is known about how these mechanisms differ. one reason is that information on these systems in very closely related diurnal and nocturnal species is lacking. in this study, we characterize the suprachiasmatic nucleus (scn), the primary brain structure involved in the genera ...201020134153
distribution of androgen and progesterone receptors in the spiny mouse (acomys cahirinus) ovary during postnatal life.this study describes the localization of androgen (ar) and progesterone (pr) receptors in the developing ovary in the spiny mouse. the immunohistochemical analysis showed for the first time the expression of ar and pr proteins in the ovary as early as in one day-old females. both ar and pr were present in germinal epithelium cells, stromal cells as well as in the granulosa and theca layer of ovarian follicles. on days 7, 14, 21, 30, 60 and 90, the distribution of ar and pr depended on the stage ...201020349022
infestation experience of a rodent host and offspring viability of fleas: variation among host-parasite associations.we studied survival and development of preimagoes and the ability to withstand starvation of adults in two flea species, host-specific parapulex chephrenis and host-opportunistic xenopsylla ramesis, when parent fleas fed on a typical (acomys cahirinus and dipodillus dasyurus, respectively) or an atypical (d. dasyurus and a. cahirinus, respectively) rodent host that either had never been parasitized by fleas (pristine) or had previously been exposed to fleas. we asked whether a repeatedly infeste ...201020853416
acomys, the closest relatives to gerbils, do express pdx-1 protein and have similar islet morphology to gerbils.acomys, also called spiny mice, were once used as a diabetes model. we have recently demonstrated that the closest relatives to the acomys, members of the family gerbillinae, lack the transcription factor pdx-1. therefore, we sought to determine if members of this family also lack pdx-1, and describe the pancreatic morphology in three different species of acomys: acomys cahirinus (egyptian spiny mouse), acomys cilicicus (asia minor spiny mouse) and acomys dimidiatus (eastern spiny mouse). we suc ...200921099272
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