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chromosomal pairing in deer mice heterozygous for the presence of heterochromatic short arms.the pattern of chromosomal pairing was analyzed in male deer mice (peromyscus maniculatus and peromyscus sitkensis) heterozygous for the presence of heterochromatic short arms. g- and c-banding of somatic metaphases indicated that the presence of heterochromatic short arms increased the length of chromosome 4 by 15% in p. sitkensis and that of chromosome 8 by 9% in p. maniculatus. analysis of silver-stained late zygotene and early pachytene nuclei revealed a low frequency of unequal axial length ...19883371655
identification of p-450alc in microsomes from alcohol dehydrogenase-deficient deermice: contribution to ethanol elimination in vivo.isozyme 3a of rabbit hepatic cytochrome p-450, also termed p-450alc, was previously isolated and characterized and was shown to be induced 3- to 5-fold by exposure to ethanol. in the present study, antibody against rabbit p-450alc was used to identify a homologous protein in alcohol dehydrogenase-negative (adh-) and -positive (adh+) deermice, peromyscus maniculatus. the antibody reacts with a single protein having an apparent molecular weight of 52,000 on immunoblots of hepatic microsomes from u ...19883395117
susceptibility of the gray wolf (canis lupus) to infection with the lyme disease agent, borrelia burgdorferi.four juvenile gray wolves (canis lupus) were inoculated with live borrelia burgdorferi. one received an intravenous inoculum, a second was inoculated subcutaneously, and two more were fed peromyscus maniculatus sucklings which had earlier been inoculated with b. burgdorferi. the intravenously inoculated wolf developed a generalized lymphadenopathy and a persistent serum antibody titer to the spirochete which peaked at 1:512. borrelia burgdorferi was visualized in liver sections of this wolf usin ...19883411709
stress-induced opioid analgesia and activity in deer mice: sex and population differences.we compared restraint stress-induced opioid, analgesic and locomotory responses of 4 different populations of male and female deer mice, peromyscus maniculatus artemisiae and p. m. nebrascensis from mainlands, and p. m. angustus and p. m. triangularis from small islands. all of the deer mice displayed immobilization-induced analgesia which was blocked by the prototypical mu-opiate antagonist, naloxone (1.0 mg/kg). in all of the populations males displayed significantly greater levels of analgesi ...19873427425
the molecular organization of the beta-globin complex of the deer mouse, peromyscus maniculatus.recombinant dna clones have been isolated that contain 80 kb of the beta-globin complex from the deer mouse, peromyscus maniculatus. comparisons of this complex with that from the laboratory mouse, mus domesticus (with an order 5'-hbby, hbb-bho, hbb-bhl, hbb-bh2, hbb-bh3, hbb-bl, hbb-b2 3') highlight organizational trends in the beta-globin complex since the two species diverged. unlike other mammals studied thus far, the deer mouse possesses three adult genes. partial sequence analysis indicate ...19873447002
accelerated wound repair in old deer mice (peromyscus maniculatus) and white-footed mice (peromyscus leucopus).the closure of bilateral full thickness cutaneous wounds, made over the back with a sharp paper punch, was measured and assessed histologically in outbred deer mice (peromyscus maniculatus) and white-footed mice (peromyscus leucopus). in contrast to inbred c57bl/6j laboratory mice (mus musculus), in which the rate of wound repair was more rapid in young than in mature or aged mice (cohen et al., 1987), wound repair in peromyscus was most rapid in aged animals. aged peromyscus (45 to 70 months) a ...19873571866
platinum coat color locus in the deer mouse.platinum coat color in the deer mouse, peromyscus maniculatus, is an autosomal recessive trait marking a locus, pt, distinct from silver (si), albino (c), blonde (bl), brown (b), and agouti (a). platinum deer mice are conspicuously pale, with light ears and tail stripe. the pewter trait is allelic with and phenotypically identical to platinum, and represents an independent recurrence of this mutant. the rate of recoveries of coat color mutations from wild deer mice is consistent with available d ...19873611714
neurons in the suprachiasmatic area are labelled after intravenous injections of horseradish peroxidase.intravenous injections of horseradish peroxidase (hrp) produced labelled neurons in the suprachiasmatic area of house mice (mus musculus), deer mice (peromyscus maniculatus bairdi), and white-footed mice (peromyscus leucopus). in the two species of peromyscus, a significant proportion of the labelled cells was found within the suprachiasmatic nucleus (scn). these results suggest that when hrp is injected in the eyes to trace retinal inputs to the hypothalamus, some of the reaction product seen i ...19873622673
gonadal regression induced by caloric restriction is not mediated by the pineal gland in deer mice (peromyscus maniculatus).the role of the pineal gland in mediating reproductive regression in response to nonphotoperiodic cues was assessed. a proportion of deer mice (peromyscus maniculatus) undergo gonadal regression subsequent to moderate food restriction. the reproductive regression after inanition qualitatively and quantitatively resembles short-day-induced regression. the physiological mechanisms responsible for gonadal regression after food restriction are unknown. the hypothesis that the mechanisms underlying p ...19873625465
sex and day-night differences in opiate-induced responses of insular wild deer mice, peromyscus maniculatus triangularis.we examined the effects of mu and kappa opiate agonists on the day- and night-time nociceptive, locomotory and ingestive behaviors of an island population of wild male and female deer mice, peromyscus maniculatus triangularis. the prototypical mu opiate agonist, morphine, had significant analgesic and locomotory effects, which were blocked by naloxone, and the specific delta opiate antagonist, ici 154,129, respectively. the specific kappa opiate agonist, u-50,488, had significant analgesic actio ...19873659070
sex differences in magnetic field inhibition of morphine-induced responses of wild deer mice, peromyscus maniculatus triangularis.an exposure for 60 min to a 0.5 hz weak rotating magnetic field (1.5-90 g) reduced the day-time locomotory and analgesic effects of morphine (10 mg/kg) in a wild population of deer mice. peromyscus maniculatus triangularis. females displayed significantly lower levels of morphine-induced responses and sensitivity to the inhibitory effects of the magnetic fields than did the males. these responses indicate that there are sex differences in the effects of weak magnetic fields on the opiate-mediate ...20133671517
disruption of ejaculates by male copulation in deer mice (peromyscus maniculatus).six experiments were conducted to analyze possible disruption of sperm transport occurring when one male deer mouse copulates soon after another male ejaculates. when a second male mated soon after the first, females had significantly fewer uterine sperm 1 hr later than when a delay of 7 or 15 min was imposed between males. however, it was impossible to detect any effect of such disruption on pregnancy initiation. similarly, artificial stimulation soon after an ejaculation was ineffective in dis ...19873685153
a model to assess survival mechanisms of parasites in a genetically defined host system.we examined a host system (peromyscus maniculatus) in which a single autosomal gene controls susceptibility or resistance to infection by the cestode parasite hymenolepis citelli. parasite deaths of both primary and secondary (challenge) infections were examined, using a probabilistic model, to see if deaths were random and uncorrelated within each genotype. within susceptible hosts, post-patent survival of primary worms was not random and heterogeneity was due to among-host effects rather than ...19863714298
effects of three plant growth regulators on the immune response of young and aged deer mice peromyscus maniculatus. 19863729546
oral infection of peromyscus maniculatus with borrelia burgdorferi and subsequent transmission by ixodes dammini.we determined if deer mice (peromyscus maniculatus) could be infected by borrelia burgdorferi and develop sufficient spirochetemia to infect larval ixodes dammini. ten p. maniculatus were infected orally with 0.05 ml phosphate buffered saline containing approximately 400 b. burgdorferi. on days 21 or 28 after infection (ai) larval i. dammini were fed on the deer mice. each of the p. maniculatus developed antibodies (up to 7 log2) to b. burgdorferi and b. burgdorferi was isolated from the blood o ...19873826500
heat loss regulation: role of appendages and torso in the deer mouse and the white rabbit.thermal conductance was subdivided into the component conductances of the appendages and torso using a heat transfer analysis for the deer mouse, peromyscus maniculatus, and the white rabbit, oryctolagus cuniculus. our analysis was based on laboratory measurements of skin temperature and respiratory gas exchange made between air temperatures of 8 and 34 degrees c for the deer mouse, and from published data for the white rabbit. two series conductances to heat transfer for each appendage and tors ...19853837023
evaporative water loss: thermoregulatory requirements and measurements in the deer mouse and white rabbit.using a physical model of the capacity for non-evaporative heat loss and measurements of metabolic heat production, i evaluated the evaporative requirements for thermoregulation in the deer mouse, peromyscus maniculatus, and the white rabbit, oryctolagus cuniculus. the physical limit to non-evaporative heat loss was calculated from the heat transfer properties of the two animals and expressed as a maximum thermal conductance (cmax). two physiologically-based thermal conductances were derived fro ...19853837024
effects of ambient temperature and altitude on ventilation and gas exchange in deer mice (peromyscus maniculatus).the effects of different ambient temperatures (ta) on gas exchange and ventilation in deer mice (peromyscus maniculatus) were determined after acclimation to low and high altitude (340 and 3,800 m). at both low and high altitude, oxygen consumption (vo2) decreased with increasing ta at ta from -10 to 30 degrees c. the vo2 was 15-20% smaller at high altitude than at low altitude at ta below 30 degrees c. increased vo2 at ta below thermoneutrality was supported by increased minute volume (vi) at b ...19853837039
chronic and acute trypanosomiasis in mice: a study by in vitro cloning of lymphohaematopoietic progenitors.a semi-solid culture system was used to study the effects of trypanosome infection in two species of mice on the propagation of progenitor cells from the bone marrow and spleen. the deer mouse (peromyscus maniculatus) survived infection with trypanosoma (t.) equiperdum for more than 15 days. during the first 10 days there was inhibition of development of granulocyte-monocyte colonies from progenitor cells in the bone marrow. b-lymphocyte progenitors in the spleen showed increased activity, produ ...19853873680
failure of 2-deoxy-d-glucose to stimulate feeding in deermice.deermice (peromyscus maniculatus) did not increase their food intake above baseline following treatment with 2-deoxy-d-glucose (2dg, 500 or 1000 mg/kg). they did eat more following food deprivation or treatment with insulin at a high dose (100 u/kg). house mice (mus musculus) showed hyperphagia to 2dg, low dose of insulin (5 u/kg) and deprivation.19853898162
low p50 in deer mice native to high altitude.whereas it is widely believed that animals native to high altitude show lower o2 partial pressures at 50% hemoglobin saturation (p50) than do related animals native to low altitude, that "fact" has not been well documented. consequently, p50 at ph 7.4, pco2(7.4), the co2 bohr effect, and the buffer slope (delta log pco2/delta ph) were determined via the mixing technique in peromyscus maniculatus native to a range of altitudes but acclimated to 340 or 3,800 m. pco2(7.4) and buffer slope were subs ...19853917990
photic cues induce multiple neuroendocrine adjustments in testicular function.neuroendocrine responses were evaluated in an outbred population of deer mice (peromyscus maniculatus nebrascensis) after exposure to an inhibitory photoperiod (8:16 light-dark) for 10 wk. deer mice were chosen as an animal model for this study because they are typical of naturally selected species that rely on environmental factors to signal the onset or cessation of annual reproductive effort. short photoperiods induced multiple neuroendocrine adjustments as judged by three types of spermatoge ...19863946637
effects of intrahypothalamically administered norepinephrine, serotonin and bombesin on thermoregulation in the deermouse (peromyscus maniculatus).norepinephrine, serotonin, and bombesin administered intrahypothalamically affected thermoregulation in the deermouse, peromyscus maniculatus. at a ta of 22 degrees c, doses of 3 micrograms and 6 micrograms of ne resulted in transient hypothermia (maximum drop of 1.6 +/- 1.0 degrees c and 4.3 +/- 2.3 degrees c, respectively). a 1.5 microgram dose of 5-ht induced a persistent hyperthermia (maximum increase of 1.8 +/- 0.8 degrees c) which persisted for more than 2 h. a 6 microgram dose of 5-ht did ...19863947967
the mechanism of autosomal synapsis and the substaging of zygonema and pachynema from deer mouse spermatocytes.surface-spread and silver-stained spermatocytes of peromyscus maniculatus and p. sitkensis were analyzed in order to develop criteria for the recognition of meiotic substages from early zygonema through early diplonema. the continuous sequence of changes in the morphology of the autosomal axes (lateral elements) of the synaptonemal complexes (sc), sex chromosome axes, and nucleoli enabled the recognition of three substages of zygonema and five of pachynema. the proposed system of subdivision is ...19863948599
photoperiodic time measurement in the male deer mouse, peromyscus maniculatus.weanling male deer mice, peromyscus maniculatus, were exposed for three weeks either to light-dark (ld) cycles with periods (t=l+d) ranging from t=23 (1l:22d) to t=25.16 (1l:24.16d) or to 24-h ld cycles with photoperiods ranging from 1 (1l:23d) to 19 (19l:5d) h. both the circadian locomotor activity rhythms and the response of the reproductive system to these ld cycles were assessed. the results demonstrate that the photoperiodic effectiveness of light depends on the phase of the light relative ...19854005352
studies of pericopulatory pregnancy blockage and the gestation period in deer mice (peromyscus maniculatus).it has previously been shown that female deer mice in cycling estrus that copulate with or are exposed to more than one male at the time of mating have a lower probability of delivering a litter than when mating with and being exposed to just one male. in the present research the effect of post-mating exposure to the bedding of a strange versus a familiar male was studied in females in postpartum estrus. in four experiments females in postpartum estrus were protected from pericopulatory pregnanc ...19854007797
reproductive development in male deer mice exposed to aggressive behavior.male deer mice (peromyscus maniculatus bairdii) were reared in a long photoperiod and housed individually from 3 weeks of age until they were killed 2, 4, or 6 weeks later. males that were exposed to aggressive females for 2 min, three times per week, were of normal body weight and healthy, but had smaller reproductive organs than did males exposed to a control treatment. reproductive development in male deer mice is responsive to at least two classes of social stimuli: pheromones and aggressive ...19854039275
eimeria species (apicomplexa: eimeriidae) infecting peromyscus rodents in the southwestern united states and northern mexico with description of a new species.of 198 deermice (peromyscus spp) collected from various localities in the southwestern united states and northern mexico, 106 (54%) had eimerian oocysts in their feces when examined. these included 50 of 106 (47%) peromyscus truei, 34 of 54 (63%) peromyscus maniculatus, 4 of 17 (24%) peromyscus leucopus, and 18 of 21 (86%) peromyscus eremicus. the following eimeria were identified from infected mice: eimeria arizonensis and eimeria langebarteli from p. truei; e. arizonensis, eimeria peromysci, a ...19854057004
effects of laryngeal denervation on ultrasound production and male sexual behavior in rodents.adult male house mice (mus musculus) and deer mice (peromyscus maniculatus bairdi) were used to investigate the effects of partial denervation of the larynx on ultrasound production. in addition the masculine sexual behavior of vocalizing and muted males was assessed on tests with receptive females. for both species, unilateral transections of the inferior laryngeal nerve (iln) significantly reduced the proportion of males that emitted ultrasonic vocalizations. however, the inability to vocalize ...19854059379
chromosome variation in peromyscus: a new mechanism.differences in total chromosome lengths between two karyotypically divergent groups of peromyscus maniculatus are taken as evidence for an deletion mechanism of chromosomal variation in the species. the differences may be due in part to variation in the amount of constitutive heterochromatin in the two karyotypes.20144113739
chromosomes of peromyscus (rodentia, cricetidae). 3. polymorphism in peromyscus maniculatus. 19724119112
control of plague vectors on peromyscus maniculatus by use of 2 percent carbaryl dust in bait stations. 19744208145
pathogenesis of trypanosoma equiperdum in deer mice (peromyscus maniculatus). 19744210290
modoc viral infections in the deer mouse peromyscus maniculatus.the pathogenesis of modoc virus and its mechanism of transmission were investigated in peromyscus maniculatus gambeli (deer mouse) as a model to understand the natural history of this virus. animals were readily infected by the intranasal or subcutaneous route of inoculation. virus could be detected by direct isolation techniques in many organs and body fluids during the first 7 to 9 days after intranasal inoculation. increases in viral titers were detectable first in lungs and then the spleen, ...19744215763
recovery of an adenovirus from a feral rodent peromyscus maniculatus. 19674290459
some developmental observations on the effects of prolonged deprivation of low-voltage fast-wave sleep in the deermouse, peromyscus maniculatus bairdi. 19714353538
experimental infection with western equine encephalomyelitis virus in wild rodents indigenous to kern county, california.six species of rodents from kern county, california, were inoculated subcutaneously with western equine encephalomyelitis (wee) virus to determine their susceptibility to infection and their potential as natural hosts. ammospermophilus nelsoni, citellus beecheyi, dipodomys heermanni, dipodomys nitratoides, peromyscus maniculatus, and sciurus griseus were readily infected. infection was usually fatal in dipodomys species, c. beecheyi, and s. griseus, but was clinically inapparent in other species ...19744426699
the ecology of the deer mouse, peromyscus maniculatus, in a coastal coniferous forest. iii. stomach-weight variation. 19744434276
genetic compatibility of peromyscus maniculatus and peromyscus melanotis, as indicated by breeding studies and morphometrics. 19744443646
artificial insemination of deermice (peromyscus maniculatus) with sperm from other rodent species. 19744448940
peromyscus: effect of early pairing on reproduction.sibling mating in prairie deer mice (peromyscus maniculatus bairdi) results in poor reproductive performance. siblings experimentally paired before puberty exhibit delayed reproduction when adult. a behavioral mechanism is involved in this reproductive delay, since prepubertal familiarity also delays reproduction in nonsibling pairs. such a reproductive delay may act to reduce inbreeding depression and regulate population growth.19744469697
intake and requirements of energy and protein for the breeding of wild deermice, peromyscus maniculatus. 19734522377
odor preferences of female peromyscus maniculatus bairdi for male mouse odors of p. m. bairdi and p. leucopus noveboracensis as a function of estrous state. 19724673475
host resistance in a natural host-parasite system. resistance to hymenolepis citelli by peromyscus maniculatus. 19734687483
observations on the breeding success of the deer mouse, peromyscus maniculatus nubiterrae. 19734705258
reactions of deer mice (peromyscus maniculatus) and white-footed mice (peromyscus leucopus) to homospecific and heterospecific urine odors. 19734737448
recovery of reproductive function by prairie deermice (peromyscus maniculatus bairdii) from asymptotic populations. 19734748748
immunity to hymenolepis citelli by peromyscus maniculatus: genetic control and ecological implications. 19744814797
emotionality and alcohol selection in deer mice (peromyscus maniculatus). 20164827295
studies on sylvatic echinococcosis. iv. ecology of echinococcus multilocularis in the intermediate host, peromyscus maniculatus, in north dakota, 1965-1972. 19744847041
7s-gamma-1, 7s-gamma-2 and igm immunoglobulins in the deer mouse (peromyscus maniculatus). 19694981681
growth in two subspecies of peromyscus maniculatus. 19725016684
a comparative and developmental analysis of the midventral sebaceous glands in 18 taxa of peromyscus, with an examination of gonadal steroid influences in peromyscus maniculatus bairdii. 19725016688
novelty-induced self-food deprivation in wild and semi-domestic deermice (peromyscus maniculatus bairdii). 19725058880
effects of olfactory experience on aggression in mus musculus and peromyscus maniculatus. 19725064952
behavioral consequences of crowding in the deermouse (peromyscus maniculatus). 19725066262
chromosome polymorphism in interbred subspecies of peromyscus maniculatus (deer mouse). 19715110191
hormonal regulation of srna methylase activity in regional brain areas in peromyscus maniculatus bairdii. 19715113522
postnatal development in peromyscus maniculatus-polionotus hybrids. ii. tail and hind foot growth. 19715143701
yersinia philomiragia sp. n., a new member of the pasteurella group of bacteria, naturally pathogenic for the muskrat (ondatra zibethica).a bacterium experimentally pathogenic for muskrats (ondatra zibethica), white mice, mountain voles (microtus montanus), and deer mice (peromyscus maniculatus) was isolated from the tissues of a sick muskrat captured on the bear river migratory bird refuge (brigham city, utah) and from four surface water samples collected within 15 miles of that point. in culture, the cells are chiefly coccoid, but in the tissues of muskrats and voles they resemble the bizarre forms of yersinia pestis, except for ...19695361214
weights of selected organs of deer mice (peromyscus maniculatus bairdii) from asymptotic laboratory populations. 19695362361
topography and vascularization of brown fat in a small nonhibernator (deer mouse, peromyscus maniculatus). 19695378703
the karyotype in peromyscus maniculatus nubiterrae. 19695389197
chromosomes of peromyscus (rodentia, cricetidae). ii. the y chromosome of peromyscus maniculatus. 19705412047
chromosome polymorphism in deer mouse siblings (peromyscus maniculatus). 19705439624
sea-level and high-altitude breeding colonies of peromyscus maniculatus sonoriensis. 19705461949
papillomas (warts) in hairless mice. mus musculus and peromyscus maniculatus gambeli. 19705515192
correlations between physiological parameters of blood and altitude in peromyscus maniculatus. 19715581378
the chromosomes of peromyscus maniculatus hollesteri (deer mouse). 19675594480
electrophoretic examination of hemoglobin and plasma proteins from three altitude groups of peromyscus maniculatus nerbascensis. 19685651282
hemoglobin polymorphism in the deer mouse, peromyscus maniculatus. 19685717667
echinococcus multilocularis in peromyscus maniculatus and vulpes vulpes from minnesota. 19685757663
studies on sylvatic echinococcosis. 1. ground beetle transmission of echinococcus multilocularis leuckart, 1863, to deer mice, peromyscus maniculatus (wagner). 19685757728
axonal dystrophy in a deer mouse (peromyscus maniculatus) with an inherited ataxia and tremor. 19695787431
malignant tumors associated with subcutaneously implanted 60co radioactive wires in peromyscus maniculatus. 19695817789
cestode in north dakota: echinococcus in field mice.field mice (microtus pennsylvanicus and peromyscus maniculatus) are naturally infected with echinococcus multilocularis. thus, the sylvatic cycle (fox to field mice to fox) has been established in north dakota. this cestode is expected to extend its range to other agricultural regions of the continental united states where similar conditions favorable for the completion of its life cycle exist.19655891703
haemoglobin variants in a species of wild mice-peromyscus maniculatus. 19665914910
hexose-6-phosphate dehydrogenase found in human liver.starch-gel electrophoresis of extracts of human liver revealed the presence of a new hexose-6-phosphate dehydrogenase that was slower-moving at ph 8.6 than the sex-linked glucose-6-phosphate dehydrogenase. when the gel plate was stained, galactose-6-phos phate being used as a substrate, this enzyme band stained intensely, but the sex-linked glucose-6-phosphate dehydro genase failed to stain. this new human enzyme may well be homologous with the autosomally inherited glucose-6-phosphate dehydroge ...19665917551
distress vocalizations of young in two subspecies of peromyscus maniculatus. 19665930720
autosomal polymorphism due to pericentric inversions in the deer mouse (peromyscus maniculatus), and some evidence of somatic segregation. 19665932751
mice: individual recognition by olfactory cues.mice discriminated between two male mice of the same inbred strain on the basis of olfactory cues. mice could also discriminate by olfactory cues between two different species, c3h mus musculus and peromyscus maniculatus, and between males and females.19676057298
adrenal weight in prairie deer mice (peromyscus maniculatus bairdii) and white-footed mice (peromyscus leucopus noveboracensis). 19676070648
a possible role for the thyroid in reproductive inhibition in laboratory populations of the prairie deermouse (peromyscus maniculatus).serum thyroxine concentrations were determined and found to be reduced in reproductively inhibited deermice selected from controlled growth laboratory populations. daily injections of 1 microgram thyroxine in reproductively inhibited male deermice were shown to significantly increase testis weight and the number of spermatids with acrosome formation. daily feeding of thyroxine to a controlled growth population promoted an increase in the mean weights of the reproductive organs of both sexes that ...19846142798
serum acth and adrenal histology in reproductively inhibited male prairie deermice (peromyscus maniculatus bairdi).exogenous acth will cause adrenal hypertrophy and gonad dysfunction in reproductively capable male deermice. the ultrastructure of the zona fasciculata of inhibited animals is substantially different from acth stimulated animals which suggests that acth alone does not produce the inhibition. although acth concentrations were variable, there was no clear demonstration that any differences existed between reproductively capable vs inhibited animals at the time when corticosterone is known to be el ...19846146448
linkage relationships among eleven biochemical loci in peromyscus.interspecific f1 hybrids of peromyscus maniculatus (deermice) and p. polionotus (oldfield mice) were backcrossed to p. maniculatus. backcross progeny were electrophoretically typed for 11 variant protein markers: albumin, transferrin, leucine aminopeptidase, amylase, 6-phosphogluconate dehydrogenase, nucleoside phosphorylase, dipeptidase, tripeptidase, glutamate oxaloacetate transaminase, alcohol dehydrogenase, and sorbitol dehydrogenase. genetic variation for each protein was attributed to a si ...19836200103
experimental colorado tick fever virus infection in colorado mammals.one hundred and twenty-four small mammals of six species were inoculated with three strains of colorado tick fever (ctf) virus to define viremia and neutralizing (n) antibody responses. adult eutamias minimus and eutamias embrinus, and juvenile peromyscus maniculatus and spermophilus lateralis, were highly susceptible to development of viremic infection. adult s. lateralis and p. maniculatus were moderately susceptible (greater than or equal to 50% viremic). five sylvilagus nuttalli did not beco ...19816259958
the ecology of colorado tick fever in rocky mountain national park in 1974. ii. infection in small mammals.field studies of colorado tick fever (ctf) in small mammals in rocky mountain national park (rmnp) in 1974 established that eutamias minimus and spermophilus lateralis were the most important hosts for ctf virus and were the source of virus for immature stages of the tick vector, dermacentor andersoni. other species (peromyscus maniculatus, spermophilus richardsonii, eutamias umbrinus) are secondary hosts. the intensity of viral activity in rodents varied greatly from locality to locality. highe ...19816263122
effects of experimental infection of the deer mouse (peromyscus maniculatus) with mouse hepatitis virus.three deer mice (peromyscus maniculatus) given 10(4) tcid50 of mouse hepatitis virus -s intranasally all had significant serum neutralization titers to mouse hepatitis virus -s 3 weeks later. ten other deer mice were given 10(3) tcid50 of mouse hepatitis virus -3 intranasally and placed with sentinel laboratory mice (cf1, c3h/rv, and nu/nu) and uninoculated deer mice. one inoculated deer mouse died, but mouse hepatitis virus was not isolated. no other inoculated or uninoculated animals exhibited ...19826285078
medroxyprogesterone, immunosuppression, and conceptus size in peromyscus.effects of exogenous medroxyprogesterone acetate (mpa) on skin transplant retention and conceptus size were studied in the deer mouse, peromyscus maniculatus, and the oldfield mouse peromyscus polionotus. daily injections of 2 mg mpa significantly prolonged survival of allografts in p. maniculatus and transspecific grafts between p. maniculatus and p. polionotus. allografts were retained significantly longer than transspecific grafts (17.2 vs 12.4 days) on mpa-treated p. maniculatus. near-term f ...19836345716
normal testicular structure and reproductive function in deermice lacking retinol and alcohol dehydrogenase activity.it was found that a strain of deermice (peromyscus maniculatus), which genetically lacks liver alcohol dehydrogenase activity also displays no such activity in the testis and is devoid of the enzyme activity that converts retinol to retinal, both in liver and in the testis; nevertheless, these animals exhibit normal reproduction and testicular histology. therefore, one must reconsider the theory that the testicular atrophy and aspermatogenesis commonly found in alcoholics is due, at least in par ...19846365975
non-alcohol dehydrogenase-mediated metabolism of methylazoxymethanol in the deer mouse, peromyscus maniculatus.the concept that alcohol dehydrogenase (adh) is involved in the metabolism of methylazoxymethanol (mam) was examined in a model consisting of two strains of the deer mouse, peromyscus maniculatus, one of which has a normal complement of the enzyme [adh(+)], and the other, which completely lacks it [adh(-)]. both the adh(+) and the adh(-) strains rapidly metabolized [14c]mam, administered in the form of the acetic acid ester, [14c] mamoac , to 14co2, and the rates and extents of metabolism were v ...19846372998
reservoirs of giardia spp. in southwestern alberta.a survey of potential hosts of giardia spp. was carried out during 1982 and 1983 in the kananaskis valley and banff national park, alberta, canada. diagnosis was based mainly on fecal analysis but a few animals were examined at necropsy and scrapings from the small intestine analyzed. a total of 304 specimens was examined from humans (homo sapiens l.) and a variety of animal species. cysts and/or trophozoites of giardia were found in 10.5% of the specimens examined. positive samples were found f ...19846397598
effect of indomethacin on reproduction under laboratory and field conditions in deermice (peromyscus maniculatus).the purpose of this investigation was to determine the long-term effect of enterically administered indomethacin (a prostaglandin synthetase inhibitor) on reproduction in peromyscus maniculatus (deermice) under both laboratory and field conditions. indomethacin-coated wheat (1 mg/kg wheat) was provided to the experimental animals in the laboratory and under field conditions ad libitum. rat chow was also provided to the animals in the laboratory. the laboratory data indicate that the number and s ...19836403066
evidence for heterosynaptic pairing of the inverted segment in pericentric inversion heterozygotes of the deer mouse (peromyscus maniculatus).silver-stained pachytene cells of male deer mice, peromyscus maniculatus, which were heterozygous for a naturally occurring pericentric inversion of chromosome 6, were analyzed by light microscopy. the presence of the terminally positioned inversion, involving approximately 30% of the length of chromosome 6, was detected by g-banding. within the inversion, c-band-positive heterochromatin was restricted to the centromeric region. silver-staining of spermatocytes revealed the synaptonemal complexe ...19846467983
involvement of the circadian system in photoperiodic control of pubertal development in female deer mice, peromyscus maniculatus.pubertal development in female deer mice, peromyscus maniculatus, was stimulated by exposure to light cycles of ld 16:8, ld 6:30 or ld 6:54, but not by exposure to cycles of ld 6:18 or ld 6:42. these results support the hypothesis that female deer mice use a circadian rhythm of responsiveness to light to measure photoperiodic time.19846468610
kinetics of cytoplasmic aspartate aminotransferase from three genotypes of the deer mouse (peromyscus maniculatus).three genotypic forms of the cytoplasmic enzyme, aspartate aminotransferase from the deer mouse (peromyscus maniculatus) were each analyzed kinetically after partial purification. kmapp and vmax for aspartate decreased in value as temperature changed from 37.9 to 15 degrees c for all three forms. for the aa genotype, the binding enthalpies were highest at 37.9 degrees c and lowest at 25 degrees c, while for the a'a' form, they were lowest at 37.9 degrees and highest at 25 degrees c. results for ...19846478801
atropine esterase status of laboratory mice.fifty eight inbred strains of laboratory mice and two species of wild mice [mus castaneus (inbred) and peromyscus maniculatus bairdii (closed colony)] were tested for the presence of atropine esterase by the microhematocrit tube test of tucker and beattie. the results show clearly that laboratory mice do not have significant levels of atropine esterase as determined either by the microhematocrit tube test or by the agar plate test, and therefore that under these conditions atropine esterase is n ...19846482377
industrial lead contamination of an illinois wildlife refuge and indigenous small mammals.deer mice (peromyscus maniculatus) were trapped from a sand prairie at various distances from an adjacent battery lead reclamation plant. analysis of liver, kidney, and bone for lead concentrations showed an increase of tissue lead concentrations over controls to a distance of approximately 400 m. soil and plant lead concentrations roughly correlated with the findings in deer mouse tissues. at higher tissue lead concentrations, acid-fast staining intranuclear inclusions within renal tubular epit ...19846511573
photosensitive stages in pubertal development of male deer mice (peromyscus maniculatus).male deer mice (peromyscus maniculatus bairdii) were exposed to a long (15l:9d) or short (6l:18d) photoperiod during four stages of development. at 6 weeks of postnatal age degree of pubertal development was determined by measurement of testis and seminal vesicle weights and area of the androgen-dependent sebaceous gland. continuous exposure to a short photoperiod beginning before conception (i.e. mother kept in short days), at conception, or at birth markedly retarded pubertal development. init ...19846512755
effect of transitional photoperiods on testicular development and puberty in male deer mice (peromyscus maniculatus).in a series of five experiments, young male deer mice (peromyscus maniculatus bairdii) were exposed to photoperiods ranging in length from 3 to 19 h per 24-h period, as well as to constant light and constant darkness. reproductive organ growth as measured at 6 weeks of age was inhibited by less than or equal to 11.5 h of light. in males receiving 11.5-19 h of light, there was a quantitative increase in reproductive organ size as a function of photoperiod. rather than a 'critical' photoperiod par ...19846512756
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