Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| serum concentrations of thyroid hormones and activity of iodothyronine deiodinase in peripheral tissues of the house musk shrew, suncus murinus. | serum concentrations of thyroid hormones and the properties of iodothyronine deiodinase in tissues of the house musk shrew, suncus murinus, were examined and compared with those of the rat. serum concentrations of thyroxine (t4) and 3,3',5'-tri-iodothyronine (rt3) were higher, while the serum concentration of 3,5,3'-tri-iodothyronine (t3) was lower in the shrew than in the rat. among liver, kidney, skeletal muscle, heart, brown adipose tissue (bat), spleen, lung, testes and thymus homogenates of ... | 1990 | 2338528 |
| the ultrastructure of the ganglionated nerve plexus in the nasal vestibular mucosa of the musk shrew (suncus murinus, insectivora). | a ganglionated nerve plexus (gnp) found in the nasal vestibular mucosa of the adult musk shrew, and most likely belonging to the nervus terminalis, was studied by electron microscopy. the gnp, which contained ganglion cells and both myelinated and unmyelinated nerve fibers, was located in the subepithelial layer of the mesial vestibular mucosa of the snout processes. the ganglion cells were characterized by an eccentrically located round nucleus, dispersed mitochondria and golgi apparatuses, and ... | 1990 | 2372438 |
| environmental regulation of reproduction in an opportunistic breeder: the musk shrew (insectivora: suncus murinus). | in summary, photoperiod, social cues and food availability impact upon the reproductive system of the male musk shrew to alter the timing of reproductive maturation and hence opportunistic breeding. we can speculate that there might be a hierarchy to these environmental inputs. we suggest that for shrews living on guam, food availability is the primary cue, whereas social and photoperiodic signals play modulatory roles. the relative importance of these three external cues most likely depends upo ... | 1990 | 2381955 |
| genetic relationship among the musk shrews, suncus murinus insectivora, inhabiting islands and the continent based on mitochondrial dna types. | cleavage patterns of mitochondrial dna (mtdna) by restriction endonucleases were examined in musk shrews collected at six trapping sites on two japanese and two indonesian islands, on sri lanka, situated close to the indian subcontinent, and on the mainland of east bengal in bangladesh. no variation of mtdnas was found among the japanese and indonesian shrews, despite their geographical isolation by the sera. in contrast, at least six mtdna types were present in the sri lanka and the bangladesh ... | 1990 | 2383245 |
| prolonged copulatory behavior facilitates pregnancy success in the musk shrew. | female musk shrews (suncus murinus) are sexually receptive and actively seek contact with males during the first ten days of pregnancy. in the series of experiments reported here we examined the effects of prolonged copulatory behavior on pregnancy success. females received multiple ejaculations either on the same day or over the course of up to six days. when ejaculations were distributed over an interval of several days, the number of females delivering litters was significantly increased. the ... | 1990 | 2388938 |
| social cues influence growth and sexual maturation of the male musk shrew (suncus murinus). | musk shrews were maintained from weaning (20 days of age) for 20 or 40 days in one of several social conditions. in exp. 1, young males housed with adult females gained more weight and had heavier sex accessory organs than did young males housed with an adult male or reared alone. in exp. 2 this same pattern of accelerated growth and sexual maturation was found when males were reared directly with an adult female or in a split cage where a wire barrier served to separate the male and his adult f ... | 1990 | 2401994 |
| effects of photoperiod and social variables on reproduction and growth in the male musk shrew (suncus murinus). | in exp. 1, the time course for the photoperiodic response in juvenile male musk shrews was examined by exposing animals to short (10l:14d) or long (14l:10d or 18l:6d) daylengths for 10, 20, 40 or 56 days. when compared with the response of animals maintained in long days, those exposed to short days showed an inhibition of reproductive maturation by 40 days of treatment. in exp. 2, the combined effects of photoperiod and social cues were investigated in juvenile males that were either housed in ... | 1990 | 2401995 |
| biochemical and immunological characterization of suncus murinus mammary tumor virus dna polymerase. | enzymological properties of the rna-directed dna polymerase associated with the suncus murinus mammary tumor virus (sm-mtv) was investigated and its antigenic relatedness to other retroviral dna polymerases was examined. the enzyme exhibited higher activity in the presence of mg2+ than in the presence of mn2+ with endogenous rna as well as with almost all of the synthetic template x primers tested. mg2+ was also effective with poly(2'-o-methylcytidylate) x oligodeoxyguanylate which was known to ... | 1986 | 2417416 |
| ultrastructural characterization of the retrovirus particles (sm-mtv) liberated from the mammary tumor cell line (sm-mt) of a house musk shrew, suncus murinus (insectivora). | detailed ultrastructure of a new type of retrovirus (sm-mtv) released by cultured cells (sm-mt) of a spontaneous mammary tumor from a house musk shrew suncus murinus, insectivora, is described. the virus particles were revealed as three forms: intracellular; budding; and extracellular. the intracellular type a particles were similar in profile to those associated with mouse mammary tumor cells and tended to form a small cluster of several particles in the cytoplasm. in addition, horseshoe-shaped ... | 1986 | 2421890 |
| sensory innervation of gingival and alveolar mucosa of the house musk shrew (suncus murinus). | the lingual gingival and the alveolar mucosa of mandible of the house musk shrew (suncus murinus) were stained by methylene blue vital staining or osmic acid staining, and mounted as whole thickness preparations. the sensory innervation and the distribution of sensory receptors were investigated with a light microscope. the nerve fibers supplying these regions derive from the sublingual nerve, which ascend in the mucosa as they branch out. sensory receptors found in the present study are of four ... | 1986 | 2435019 |
| major structural polypeptides of retrovirus produced by a suncus murinus mammary tumor cell line and type d retrovirus share interspecies antigenic determinants. | constitutive polypeptides of retrovirus produced by a suncus murinus mammary tumor cell line (sm-mtv) were characterized by immunofluorescence and immunoblotting. the major structural polypeptide of sm-mtv, molecular weight 44/43k, immunologically cross reacted with the structural polypeptides of mason-pfizer monkey virus (mpmv) (molecular weights 27k and 12/10k). sm-mtv constitutive polypeptides did not show antigenic relatedness with those of the following mammalian retroviruses: murine mammar ... | 1988 | 2460996 |
| nucleotide sequence of suncus murinus immunoglobulin mu gene and comparison with mouse and human mu genes. | both primates and rodents apparently originated from insectivores and then evolved separately. we isolated the immunoglobulin mu gene from dna of the insectivore suncus murinus and determined its nucleotide sequence. the gene organization was ch1 exon (318 bp)-intron (89 bp)-ch2 exon (345 bp)-intron (80 bp)-ch3 exon (318 bp)-intron (85 bp)-ch4 exon (392 bp)-coding sequence and 3'-untranslated region. comparison of nucleotide sequences of mu genes between mouse, human and suncus murinus indicated ... | 1989 | 2497033 |
| characterization of three forms of cytochrome p-450 inducible by 3-methylcholanthrene in golden hamster livers with special reference to aflatoxin b1 activation. | three forms of cytochrome p-450 of liver microsomes of 3-methylcholanthrene-treated golden hamsters were purified and characterized as regards their catalytic activity toward aflatoxin b1-related hepatocarcinogenic mycotoxins. these include two major forms, designated as cytochrome p-450-afb (p-450-i) and p-450-ii, and one minor form, p-450-iii. cytochromes p-450-afb, p-450-ii, and p-450-iii have their absorption maximum in the carbon monoxide-complex of the reduced form at 448.5, 447.0, and 448 ... | 1989 | 2509440 |
| [three dimensional structure of the connective tissue papillae of the tongue in suncus murinus]. | the surface structure of the connective tissue papillae (cp) of suncus murinus tongue was observed by sem after fixing with karnovsky's fixative and removal of the epithelial cell layer with 3n or 8n hcl. on the surface of the slender conical tongue, there are densely distributed filiform papillae among which fungiform papillae are seen sporadically. a pair of vallate papillae are situated in the posterior region of the tongue. filiform papillae appear somewhat different externally depending on ... | 1989 | 2519278 |
| on the distribution of elastic fibers in the filiform papillae of suncus murinus. | the distribution of elastic fibers in the filiform papillae of 1, 2, 3, 4 and 5 week-old and 6 month-old suncus (suncus murinus; insectivora) was examined by both weigert's resorcin-fuchsin method and ultrastructural means. in the adult suncus (6 months old), elastic fibers in the connective tissue core of the papillae were aligned perpendicularly to the epithelial surface and formed a palisade-like structure which encircled the margin of each connective tissue core. this characteristic structur ... | 2008 | 2519280 |
| testosterone propionate induced changes in testicular phosphatases of musk shrew (suncus murinus l.). | in order to investigate the role of testosterone (tp) on the physiology of the testis of the musk shrew, activities of acid phosphatase, alkaline phosphatase and adenosine triphosphatase, and dna, protein and phospholipid contents ot the testis were compared under high and suppressed testosterone conditions. the result indicates that testosterone propionate administration to intact shrews resulted in a significant increase in the activities of testicular enzymes. following tp the testis phosphol ... | 2013 | 2528927 |
| the distribution of endocrine cells in the mucosa of the gastrointestinal tract of the house musk shrew, suncus murinus (insectivora). | the distribution of endocrine cells in the gastrointestinal tract of the house musk shrew, suncus murinus (family soricidae, order insectivora) was studied immunohistochemically. the hormones investigated were gastrin, cholecystokinin (cck), somatostatin, secretin, glucagon, gastric inhibitory polypeptide (gip), motilin and neurotensin. in the gastric mucosa, gastrin and somatostatin cells were only found in the pyloric regions, and no other hormonal cell-types were observed. in the intestinal m ... | 1989 | 2582480 |
| ultrastructural features of the developing eosinophils in bone marrow and spleen of the musk shrew, suncus murinus. | eosinophilopoiesis in the musk shrew, suncus murinus, a representative of the order insectivora, was studied by light and electron microscopy. to examine biochemical features of cytoplasmic granules, extraction with proteolytic enzymes was carried out on ultrathin sections of bone marrow. in this species, eosinophils are produced in the same manner in both spleen and bone marrow. developing eosinophils were distinguished as belonging to four stages, recognized by ultrastructural changes in cytop ... | 1989 | 2600974 |
| scanning, transmission and immunoelectron microscopical studies of the tonsil-like lymphoid organ of normal and horseradish-peroxidase-injected laboratory suncuses. | fine structures of normal and horseradish peroxidase (hrp)-stimulated tonsil-like lymphoid organs of the laboratory suncus (suncus murinus) were examined by scanning, transmission and immunoelectron microscopies. the normal organs appear as a pair of small oval protrusions at the upper lateral sites of the fauces, and consist of a single lymph nodule with a germinal center and a crypt-like epithelium with prominent lymphoid cell infiltration. postcapillary venules (pcv) and efferent lymphatics a ... | 1989 | 2603630 |
| the intermediate epithelium lining the larynx of the suncus murinus. | in the larynx of the suncus murinus the stratified squamous epithelium lines the tip of the caudal surface of the epiglottis and the region close to the vocal process of the arytenoid cartilage, while the ciliated columnar epithelium is located in the laryngeal sac and the dorsal part of the vocal fold. further, in the transitional zone between the stratified squamous epithelium and the ciliated columnar one there exists the epithelium which shows gradations ranging from stratified squamous thro ... | 1989 | 2608258 |
| the foci of the red bone marrow observed in the laryngeal cartilages of the suncus murinus. | in the suncus murinus, the thyroid, the cricoid and the arytenoid cartilages were in part ossified. the foci of the red bone marrow, termed as the "marrow foci", were observed in the ossified portion of the cartilages. the marrow foci were filled with mature and immature blood cells. it is suggested that the marrow foci take part in active hematopoiesis in the suncus. further, a canal which connected the marrow cavity and the outside of the cartilage was occasionally seen. it seems that the cana ... | 1989 | 2608261 |
| histochemistry of glycoconjugates in ovarian follicles of the adult house musk shrew, suncus murinus. | in ovarian follicles of the adult house musk shrew, suncus murinus, glycoconjugates have been studied by means of light- and electron-microscopic histochemistry. the results obtained are that: (1) glycoconjugates of the zona pellucida of oocytes are provided with vicinal diol and acidic groupings, and sialic acid-galactose dimer, alpha-d-mannose, alpha-d-glucose, beta-d-galactose, n-acetyl-d-glucosamine and alpha-l-fucose residues; (2) glycoconjugates of the intercellular matrix of the granulosa ... | 1989 | 2609922 |
| annual profiles of sex steroids in blood plasma and ovarian tissue of wild female musk shrew, suncus murinus. | relative ovarian weights with bursa and annual profiles of sex steroids have been described in the female musk shrew, suncus murinus, collected in the vicinity of rawalpindi, pakistan. the relative gonadal weight was basal (23.20 +/- 1.20 mg/100 g) during anoestrus but enhanced (39.93 +/- 2.73 mg/100 g) abruptly at the onset of the breeding season. plasma progesterone concentrations, measured during different parts of the year, indicated elevated levels during the late pregnant stage (p less tha ... | 1989 | 2615037 |
| determination of catecholamines and their metabolites in adrenals of stress-loaded and wild suncus (suncus murinus). | the contents of catecholamines and their metabolites were measured in the adrenals of 3 groups of suncus. the first group was naive housed suncus; the second, suncus with stress-loading; and the third, wild ones. there were no significant differences in dopamine, norepinephrine and normetanephrine levels among the control, stress and wild groups. the content of epinephrine, however, decreased in the stress and wild group to 57% and 18%, respectively. these results suggest that housed suncus can ... | 1989 | 2622098 |
| chigger mite infestation of small mammals in a feral biotope of a public park area of south delhi. | examination of bandicota bengalensis (8) and suncus murinus (4) trapped in a feral biotope of a public park area of south delhi revealed presence of the known scrub typhus vector leptotrombidium (l.) deliense, the suspected vector gahrliepia (s.) ligula and gahrliepia (walchia) sp. of chigger mites, on them. the epidemiologically important population indices (chigger infestation rate-cir and incidence rate--1r) were estimated. the overall cir of the three mite species on the hosts was 2.83 mite/ ... | 1989 | 2638383 |
| major ocular glands (harderian gland and lacrimal gland) of the musk shrew (suncus murinus) with a review on the comparative anatomy and histology of the mammalian lacrimal glands. | the harderian gland of the musk shrew suncus murinus is elongated anteroposteriorly from in front of the eye to behind the ear. the gland is divided into two portions: an anterior portion (a portion) and a posterior portion (p portion). the single secretory duct of the gland emerges from the anterior end of the p portion, receives several secretory ducts of the a portion during the course along it, runs around the ventral aspect of the eyeball, and finally opens into the anterior corner of conju ... | 1989 | 2664187 |
| isolation and characterization of shrew (suncus murinus) liver alcohol dehydrogenases. | 1. starch gel electrophoresis of adult shrew (suncus murinus) liver extracts revealed five forms of alcohol dehydrogenase (adh 1-5) and four of them were purified. 2. adh-4 and adh-5 resemble human class i adh in terms of electrophoretic mobility, substrate specificity and sensitivity to pyrazole inhibition. 3. adh-2 does not belong to any of the three classes of human adhs but rather with catalytic properties similar to those of the class b adh found in guinea pig liver. 4. adh-1 prefers second ... | 1989 | 2666017 |
| male-related chemical cues promote sexual receptivity in the female musk shrew. | the role of conspecific chemical cues in the activation of sexual behavior was investigated in the female musk shrew (suncus murinus). in experiment 1, virgin female musk shrews were exposed to either clean cages or cages recently vacated by an adult male. regardless of whether the male used for the sexual behavior test was "familiar" to the female (having spent the 24 h exposure in his vacant cage) or "unfamiliar," females exposed to male-related cues received mounts from males significantly so ... | 1989 | 2705979 |
| ultrastructure of secretory ameloblasts in the house musk shrew, suncus murinus, insectivora. | tooth germs from neonatal house musk shrews, suncus murinus, were used for the study. the tooth morphogenesis was compared electron microscopically to that of primates. in the tooth germ at the bell stage, the ameloblast was 3 x 50 microns in size, columnar in shape and had several tubular-type golgi apparatus which were at the distal end of the cell. most mitochondria were noted at the proximal end of ameloblasts. tomes' processes were 1 micron in width, protruded 10 microns from the ameloblast ... | 1989 | 2718719 |
| suncus murinus. observations on ecology, distribution, status to plague in bombay. | the common house shrew suncus murinus has been shown to play an important role in maintenance and perpetuation of plague infection by earlier plague workers. with the control of human plague there is no knowledge about foci of plague in small mammals associated with man. present study was carried out to fill in this lacuna. studies carried out in the present paper reveal that s. murinus does not harbour any plague infection in bombay. this species is widely distributed in bombay and is found to ... | 1989 | 2723422 |
| comparative studies on the stereo architecture of the connective tissue papillae in some mammalian tongues. | the epithelial cell layer was removed from the underlying connective tissue papillae by the method of long term hydrochloric acid treatment and the connective tissue surface was observed by scanning electron microscopy. tongues of insectivora (suncus murinus), rodentia (mouse, rat, guinea pig), carnivores (dog, cat) and primates (man) were studied. each animal species had proper architecture of connective tissue papillae as to four types of lingual papillae. there was a tendency for the stereo s ... | 1989 | 2748642 |
| organ distribution, purification and characterization of kynureninase in suncus murinus (insectivora) and anthranilic acid level in the serum. | 1. the highest kynureninase activity was measured in suncus liver compared with other organs tested. the holo-enzyme activity detected in liver was 25%. 2. the enzyme mainly localized in liver cytosol was purified to a single protein band by heat treatment, ammonium sulfate fractionation, deae-sepharose, hydroxyapatite and phenyl-sepharose column chromatography. 3. the purified enzyme was effective for both kynurenine and 3-hydroxykynurenine, and showed the optimum ph at 8.5 against both substra ... | 1989 | 2752727 |
| effect of castration on epididymal sperm storage in male musk shrews (suncus murinus) and mice (mus musculus). | reproductively mature male musk shrews and mice were bilaterally castrated. epididymal sperm numbers and motility were assessed 0, 2, 4 and 6 weeks after surgery. seminal vesicle weights and plasma concentrations of total androgens were also measured. in male musk shrews, 30% of the original epididymal sperm numbers were still present 2 weeks after castration and motile spermatozoa were present in 2 of 7 individuals. by 4 and 6 weeks after castration the numbers of spermatozoa remaining declined ... | 1989 | 2754641 |
| development of a laboratory line (sri line) derived from the wild house musk shrew, suncus murinus, indigenous to sri lanka. | five male and 9 female house musk shrews (suncus murinus) captured in koralawella, sri lanka were acquired by our laboratory. one male and 3 females alone contributed to the development of a new laboratory line (sri line). the sri line has been maintained as a closed breeding colony consisting of more than 40 shrews. gestation period and litter size at birth averaged 31.2 days (43 cases) and 2.4 (43 litters), respectively. the sri line shrews were uniformly covered with light gray fur. the body ... | 2008 | 2792205 |
| structural and functional analysis of long terminal repeats of suncus murinus mammary tumor virus. | a 2.7-kilobase (kb) cdna sequence complementary to suncus murinus mammary tumor virus (sm-mtv) genomic rna [corrected] was prepared using purified virions produced by the sm-mt cell line, which had been established from a spontaneous mammary tumor of s. murinus. it was found, by using this cdna in southern hybridization experiments, that sm-mtv was endogenous to this animal and that some 50 copies of endogenous provirus were present per haploid cellular genome. in addition, a proviral sm-mtv dna ... | 1988 | 2831384 |
| characteristics of cardiac beta-adrenoceptors in suncus murinus. | 1988 | 2854498 | |
| isolation of haemorrhagic fever with renal syndrome virus from suncus murinus, an insectivore. | 1985 | 2857871 | |
| serum constituents and liver photomicrographs of wild suncus murinus in the south of taiwan. | serum constituents and liver of the wild male suncus as well as of those bred and fed in our laboratory were examined serologically and histologically. the following results were obtained: the serum glutamic-oxaloacetic transaminase, gamma-glutamyl transaminase, inorganic phosphate, blood urea nitrogen, creatinine, uric acid, and zinc turbidity test levels of wild suncus were higher than those of 4 and 8 week old fed suncus. the total cholesterol level of wild suncus was lower than those of 4 an ... | 1987 | 2880742 |
| cats--source of protection or infection? a case-control study of hemorrhagic fever with renal syndrome. | in the first case-control study analyzing risk factors in sporadic hemorrhagic fever with renal syndrome, 111 cases occurring in shanghai in 1983 and 1984 and 136 matched controls were studied. three factors were associated with risk of disease: travel in the month before onset of illness, intense exposure to rodents in the home, and cat ownership. risk associated with cat ownership was not confounded by exposure to rodents in the home. neither cat ownership nor risk associated with rodent expos ... | 1987 | 2889355 |
| characterization of mixed-function oxidases and purified cytochrome p-450 of livers of house musk shrew, suncus murinus. | characteristics of mixed-function oxidases in the liver of house musk shrew, suncus murinus, were studied. the basal level of cytochrome p-450 and the activity of drug-metabolizing enzyme in hepatic microsomes of suncus murinus is relatively lower than that of rats, while the level of cytochrome b5 and nadph-cytochrome c reductase is approximately the same as that of rats. the treatment of suncus murinus with phenobarbital and 3-methylcholanthrene elevated the level of cytochrome p-450 and the a ... | 1988 | 2894946 |
| suncus murinus as a new experimental model for motion sickness. | characteristics of motion sickness and effects of possible prophylactic drugs were studied using suncus murinus (house musk shrew) for its potential use as an experimental model in motion sickness. mild reciprocal shaking (amplitude: 10-40 mm; frequency: 0.5-3.0 hz) induced vomiting in most of suncus murinus within 2 min. adaptation was observed when the motion stimulus was repeated with an interval of 2 to 3 days. during the repetitive motion training, both the ratio of sensitive animals and th ... | 2010 | 2899827 |
| alanine:glyoxylate aminotransferase activities in liver of suncus murinus (insectivora). | 1. the distribution of l-alanine:glyoxylate aminotransferase (agt) activities were found in suncus liver, 55% in particulate fraction and 45% in supernatant. 2. 65% of agt activities in particulate were dependent on agt isoenzyme 2 (agt 2) having molecular weight 210,000, the remainder (35%) of agt activities were dependent on agt isoenzyme 1 (agt 1) which have aminotransferase activity for serine. agt activities in supernatant were dependent on agt 1, agt 2 and alanine:2-oxoglutarate aminotrans ... | 1988 | 2907870 |
| side gland of suncus murinus as a new model of sebaceous gland: 5 alpha-reductase, androgen receptor, and nuclear androgen content in male and female animals. | the side gland of suncus murinus is composed of well-developed sebaceous glands in both males and females. we measured the 5 alpha-reductase activity, androgen receptor content, and the intranuclear concentrations of testosterone and dihydrotestosterone in this side gland taking it as a new experimental model of human sebaceous glands. lineweaver-burk plot analysis suggested the presence of two classes of 5 alpha-reductase with different km for testosterone in the homogenate. the enzyme activity ... | 1989 | 2919895 |
| effects of prolactin and bromocriptine on physiological status of testis of the musk shrew (suncus murinus l.). | this investigation was undertaken to study the effects of prolactin and bromocriptine on the testis of the musk shrew. none of these treatments had any effect on the weight of testis or on the accessory sex organs. treatment of prolactin or bromocriptine failed to induce any change in esterified and free cholesterol content of the testis. no significant alterations were also recorded in the levels of macromolecules and in the levels of enzymes of the testis and the prostate gland. on the other h ... | 2010 | 2974686 |
| studies on shrew (suncus murinus) epidermal growth factor. | the shrew smg contains a very high level of egf. by heterologous radioreceptor assay, the egf content was determined to be about 300 pmol/mg wet weight in the male. the content is sex dependent; in the female gland, it is only 4% of the male gland level. egf level and egf receptor content in other tissues showed a reciprocal distribution pattern with the parotid gland containing the second highest level of egf and the liver containing the largest amount of egf receptor. shrew egf is heat stable. ... | 1986 | 3008480 |
| genetic differentiation between laboratory lines of the musk shrew (suncus murinus, insectivora) based on restriction endonuclease cleavage patterns of mitochondrial dna. | the cleavage patterns of mitochondrial dna (mtdna) by 17 restriction endonucleases were compared between eight lines of musk shrews derived from different wild-caught stocks. enzymatic digestion by bamhi, pvuii, xbai, and xhoi showed a cleavage pattern common to all lines that were from five japanese islands (nag, ize, oki, tku, and tr), bangladesh (ban), sri lanka (sri), and java (bog), and every line lacked cleavage sites for sali and smai. different cleavage patterns were detected by the rema ... | 1987 | 3039974 |
| preparation and characterization of monoclonal antibodies against a form of hamster liver cytochrome p-450 highly specific to aflatoxin b1. | monoclonal antibodies were prepared against a form of cytochrome p-450 (designated as cytochrome p-450-i) purified from 3-methylcholanthrene-treated hamster livers which is highly specific to aflatoxin b1. the cytochrome p-450-i was detected in elisa and western blots in liver microsomes from 3-methylcholanthrene-treated hamsters and also from non-treated and phenobarbital-treated hamsters in smaller amounts. however, none of the liver microsomes from 3-methylcholanthrene-treated rat, rabbit, gu ... | 1988 | 3132167 |
| seasonal and hormone-induced changes in testicular functions of the musk shrew suncus murinus l. | 1988 | 3169851 | |
| prenatal and postnatal development of the small intestine in the insectivore suncus murinus. | the development of the small intestine in the insectivore suncus murinus was noted during the period from 21 days' gestation to 20 days after birth. at 21 days of gestation, the proximal small intestine exhibited the beginning of villus formation, whereas the distal small intestine preserved the stratified epithelium. stratified epithelium in the distal small intestine changed into a single layer by 24 days' gestation. at 26 days' gestation, each epithelial cell was immature; but by 28 days matu ... | 1988 | 3189198 |
| emesis induced by cancer chemotherapeutic agents in the suncus murinus: a new experimental model. | acute emetic responses to seven cancer chemotherapeutic agents (adriamycin, bleomycin, cisplatin, cyclophosphamide, 5-fluorouracil, methotrexate, mitomycin c) were studied in the suncus murinus. intravenous injection of the drugs caused vomiting with various latency. cisplatin-induced emesis was prevented by the pretreatment with metoclopramide or chlorpromazine but not with domperidone. these results indicate that the suncus murinus is a useful animal for testing emetic activities of cancer che ... | 2011 | 3210455 |
| estrogen binding component in the pilosebaceous tumor developed in suncus murinus. | we transplanted a pilosebaceous tumor developed on the sidegland of suncus murinus to male nude athymic (balb/c-nu/nu) mice. this tumor can be transplanted to female hosts as well, with a lower rate of graft-taking and slower growth rate. in this study we demonstrated the presence of macromolecules which specifically bind to estrogen. measurement of 17 beta-estradiol (e2) binding by a dextran-coated charcoal assay revealed that the number of binding sites and the dissociation constant were 22.3 ... | 1988 | 3215143 |
| observations on commensal rats and their status to plague in bombay. | the distribution pattern of various types of commensal rodents in bombay city reveals that bandicota bengalensis constitutes the predominant commensal rodent species followed by r. rattus and rattus norvegicus. apart from these three types, bandicota indica, m. musculus and an insectivore (suncus murinus) are the three species of commensal small mammals that are frequently encountered in or near human habitations. these small mammals are prevalent throughout the year and their percentage distrib ... | 1988 | 3221091 |
| hormonal correlates of sexual behavior in the female musk shrew: the role of estradiol. | plasma levels of several steroid hormones in the female musk shrew, (suncus murinus), are reported along with experiments on the causational role steroids play in female sexual behavior. gonadally intact females sampled directly after a brief (about 7 minutes on average) sexual interaction with a male had equivalent plasma levels of estradiol (e2) but significantly higher plasma progesterone (p4) levels than resting females. in experiment 2, females that engaged in nonsexual activities with cons ... | 1988 | 3237803 |
| histological observations on the pharynx of the musk shrew, suncus murinus. | 1988 | 3250171 | |
| alleles at plasma alpha-amylase locus(amy-1) of the house musk shrew(suncus murinus): frequency distribution and new variants in laboratory lines and local asian populations. | among nine laboratory shrew lines originating from the japanese islands (nag, tok, tku, ize, tr and oki lines), west java (bog), bangladesh (ban) and sri lanka (sri), nag, tr and bog were fixed with amy-1b and sri with amy-1a. the remaining lines were still highly polymorphic with the two alleles. a new electrophoretic band c was found in the ban line and concluded to be expressed by a codominant allele, amy-1c, which was carried by a single heterozygous female from among eleven wild shrews of t ... | 1988 | 3260870 |
| unique features of secretory granules observed in the pituitary growth hormone-secreting (gh) cells of the musk shrew (suncus murinus l). | unique rod-shaped secretory granules were observed among oval or spherical secretory granules in gh cells of the anterior pituitary gland of musk shrew using the protein a-gold procedure combined with electron microscopy. the rod-shaped and spherical secretory granules were both immunoreactive by the immuno-gold method using antiserum to sheep gh. the rod-shaped secretory granules, which seem to be formed directly from the golgi vesicles, extend from several hundred to several thousand nm in len ... | 1988 | 3342430 |
| ultrastructural and immunocytochemical studies of prolactin-secreting cells (prl cells) in the anterior pituitary gland of the female musk shrew (suncus murinus l.). | prolactin-secreting cells (prl cells) in the anterior pituitary gland of the female musk shrew were identified by the protein a-gold procedure combined with electron microscopy. their secretory granules were spherical, and showed various sizes ranging in diameter from 100 nm to 800 nm according to the difference in physiological conditions of the animals. in pregnant and lactating animals, the prl cells exhibited morphologically active features, i.e., a large prominent golgi apparatus and a well ... | 1988 | 3382031 |
| patterns of sexual receptivity in the female musk shrew (suncus murinus). | female musk shrews (suncus murinus) were tested daily to examine patterns of sexual receptivity. when only mounting was used as a criterion (to avoid pregnancy), nonpregnant females remained sexually receptive to males every day for 14 consecutive days. when insemination was allowed, most females continued to copulate for the first 5 days of pregnancy. receptivity declined markedly around day 10 of gestation, but a few females were receptive even into late pregnancy. lactating females copulated ... | 1988 | 3397051 |
| an electron microscopical observation of the endoneurial mast cells of the laboratory musk shrew: suncus murinus). | histochemical and ultrastructural properties of endoneurial mast cells of the normal and histamine liberator compound 48/80 (48/80)--injected musk shrew, suncus murinus (suncus) were examined by light and electron microscopies. it was observed that the normal mast cells contained numerous cytoplasmic granules, with dense and irregular dense cores, covered at times with slender microvilli. the cells were diffusely located within the endoneurial sheath of the peripheral nerve fibers and in the int ... | 1988 | 3400880 |
| isolation of mycoplasmas from house musk shrews (suncus murinus). | mycoplasmas were isolated from various sites of experimental and wild house musk shrews (suncus murinus). the oral cavity was the most prominent site to harbor mycoplasmas (15/18; 83%), followed by the nasal cavity (9/18; 50%). all of the isolated strains required serum for their growth and all fermented glucose. they were found to be serologically homogeneous by growth inhibition test but did not cross-react with several type strains of mycoplasma or reference strains of murine, feline, canine, ... | 1988 | 3416940 |
| reproductive response of a tropical mammal, the musk shrew (suncus murinus), to photoperiod. | musk shrews (suncus murinus) were maintained for 8 weeks in long (16 h light:8 h darkness) or short (8 h light:16 h darkness) daylengths. males housed in short daylength had significantly lighter androgen-dependent sex accessory organs than did males kept in long daylengths. this same trend was noted in male sexual behaviour. however, the weights of the testes and epididymides and sperm numbers did not differ. females housed in short daylengths had significantly lighter cervices and were less li ... | 1987 | 3430473 |
| detection of lymphocytic choriomeningitis virus antibody in colonies of laboratory animals in japan. | indirect fluorescent antibody method was applied for a detection of lymphocytic choriomeningitis virus (lcmv) antibody in colonies of laboratory animals in japan. the results showed that the antibody exist in spf mice (3/152, 2.2%) and conventional mice (30/539, 5.6%) with the titers ranging from 1:10 to 1:160. the antibody was also detected in 2.2% (2/89) of syrian hamsters, and 2.9% (2/68) of apodemus agrarius, 21.4% (3/14) of japanese harvest mice which have been maintained as laboratory colo ... | 1986 | 3525200 |
| [vascular architecture of the spleen of the musk shrew, suncus murinus]. | 1986 | 3532676 | |
| gonadal influences on sexual behavior in the male musk shrew (suncus murinus). | in this series of experiments the hormonal bases for male copulatory behavior in the musk shrew (suncus murinus) were examined. male musk shrews failed to show copulatory behavior after castration. testosterone replacement fully reinstated sexual behavior. males castrated at birth, and tested as adults after receiving testosterone implants, did not show male-typical sexual behavior. it appears that the gonads are essential for the regulation of male sexual behavior in this primitive mammal. | 1987 | 3557329 |
| social variables influence female sexual behavior in the musk shrew (suncus murinus). | the role of social variables in the mediation of sexual behavior was examined in the female musk shrew (suncus murinus). two social variables were manipulated: amount of reproductive experience and exposure to male-related chemical cues. virgin females took significantly longer to achieve receptivity than did sexually experienced females. in addition, exposure to soiled bedding taken from a male's cage for 24-hr prior to testing reduced receptivity latencies in all females. even a brief (30 min) ... | 2013 | 3568606 |
| a new experimental animal for the study of age-related changes in serotonergic neuronal activity in the brain cortex. | calcium uptake by the cortical synaptosomes in a rodent (fischer rat) and an insectivore shrew (suncus murinus) was detected as a parameter reflecting molecular dysfunction of the aging brain. the change in calcium uptake by the cortical synaptosomes in both species was concomitant which showed less than half the capacity at 24 months old animals compared with those at 8 months old. on the other hand, 5-hydroxytryptamine binding and imipramine binding to the membrane fraction of aging rat brain ... | 1987 | 3574597 |
| failure of hcg treatment in depleting testicular cholesterol content of the musk shrew (suncus murinus l) in different seasons. | 2013 | 3583336 | |
| role of the ovary and adrenal gland in the sexual behavior of the musk shrew, suncus murinus. | the contributions of the ovary and the adrenal gland to sexual behavior were examined in the female musk shrew (suncus murinus). ovariectomy eliminated sexual behavior, and treatment with estradiol or testosterone restored it in almost all shrews. progesterone was ineffective in this regard. adrenalectomy, likewise, blocked sexual behavior in most females with intact ovaries. taken together, these results suggest that sexual behavior in this primitive eutherian mammal is normally modulated by se ... | 1987 | 3593838 |
| suncus murinus: a new experimental model in emesis research. | effects of various emetic and antiemetic drugs were studied using suncus murinus for its potential use as an experimental model in emetic research. subcutaneous injection of nicotine bitartrate (10-15 mg/kg), veratrine sulfate (0.5-1.0 mg/kg), emetine dihydrochloride (40-80 mg/kg) and oral administration of copper sulfate (20-100 mg/kg) caused dose-dependent emesis in suncus. the ed50 of nicotine, veratrine, emetine and copper sulfate were 7.9, 0.4, 47.6 and 21.4 mg/kg, respectively. however, su ... | 1987 | 3600192 |
| scent marking in the musk shrew (suncus murinus). | the hormonal regulation of scent marking was examined in male and female musk shrews. in males castration depressed flank, perineal, and throat marking frequencies, and a physiological dose of testosterone restored perineal and throat marking to intact levels. females exhibited high levels of marking whether tested in a non-pregnant state, late in gestation, or when post-partum. moreover, ovariectomy had no influence on marking behavior. adrenalectomy, in addition to ovariectomy, caused a signif ... | 2012 | 3602119 |
| morphological and reproductive characteristics of musk shrews (suncus murinus) collected in bangladesh, and development of the laboratory line (ban line) derived from them. | to establish a unique laboratory line of the musk shrew with different genetic properties from previously developed laboratory lines, 49 male and 49 female shrews were captured in the campus of bangladesh agricultural university from october through november in 1983 and from december in 1985 to january in 1986. the shrews collected were of various ages. they had light gray coats, with slight variations in color. except for the 12 shrews introduced into our laboratory, the total length and body w ... | 1987 | 3678369 |
| ouabain susceptibility of heart muscle of the house musk shrew, an insectivore: a comparison with the rat, guinea pig and rhesus monkey. | the susceptibility to ouabain of the heart muscle of the house musk shrew (suncus murinus), an insectivore, was investigated by means of in vitro experimentation, and compared with the rat, guinea pig, and rhesus monkey. contraction of the electrically driven heart muscles of all species slowly increased following application of ouabain. the shrew was approximate 100-fold more sensitive than the rat and 10-fold less than the guinea pig and rhesus monkey. only the rat heart preparation that was a ... | 1987 | 3694428 |
| mammalian sex chromosomes. i. cytological changes in the chiasmatic sex chromosomes of the male musk shrew, suncus murinus. | the x and y chromosomes of the musk shrew are the two largest in the complement and they regularly form a single chiasma during meiosis. this chiasma is located in the short arms of the x and y, both of which show partial c-banding at meiosis. the in vitro incorporation of 5-bromodeoxyuridine/tritiated thymidine during late s reveals that the non-c-band region of the y finishes replication later than the c-band positive heterochromatin. during meiosis, the sex bivalent opens out early in pachyte ... | 1986 | 3698750 |
| anatomy and histology of the musk shrew (suncus murinus) prostate. | gross anatomy and the light and electron microscopic characteristics of the musk shrew (suncus murinus, insectivora) prostate are described. the prostate is a pair of compound tubuloalveolar glands with one main excretory duct for each gland. each gland is divided into ventral and dorsal lobes. the tubuloalveoli are larger in diameter and the secretory cells are lower in the ventral than in the dorsal lobes. probable spontaneous release of secretory granules and accumulation of secretory materia ... | 1986 | 3703747 |
| serum constituents of suncus murinus. | blood samples were collected by cardiac puncture from nine-week-old suncus, mice and rats those had been fasted for 16 hours, and the serum was assayed for the levels of corticosterone, cortisol, and other constituents. the following results were obtained: the serum levels of corticosterone and cortisol and corticosterone/cortisol ratio of suncus were about the same as those of human. the sgpt, gamma-gt, alp, ldh, ca and k values in suncus were all within the normal range of the respective value ... | 1986 | 3709676 |
| acute hepatotoxicity induced by hepatotoxins in suncus murinus. | a comparative study was conducted to contrast the hepatotoxicity of several chemicals in the musk shrew (suncus murinus) versus other common laboratory species (mouse or rat), and the following results were obtained from serum enzymes (sgot and sgpt) and histopathological findings of liver specimens. the sensitivity of suncus liver to ccl4 was different from that of mouse liver. the sensitivity of suncus liver to beta-d-galactosamine was weaker than that of rat liver. the sensitivity of suncus l ... | 1986 | 3735458 |
| absence of the central canal and its obliterative process in the house shrew spinal cord (suncus murinus). | through studies of the spinal cord in a large series of the developmental stages of embryos, infant and adult house shrews (suncus murinus), the central canal provided with ependymal cells was, using the light and electron microscopes, observed to disappear. the canal was obliterated completely from the level of the area postrema to the end of the spinal cord in the infant and adult animals and remained unreformed, the cause being entirely due to spontaneous cell death of ependymal cells lining ... | 1986 | 3740446 |
| pharmacological characteristics of the contractile response of the vas deferens in shrews (suncus murinus). | 1986 | 3821064 | |
| [morphological study on the development of cheek tooth germs in the suncus murinus fetus (soricidae, insectivora)]. | 2013 | 3869784 | |
| isolation of the epidermal growth factor from the shrew submaxillary gland. | the epidermal growth factor (egf) from the submaxillary glands of the chinese shrew (suncus murinus) is purified to apparent homogeneity by using a sequence of four chromatographic steps, viz. gel filtration on sephacryl s-200, affinity chromatography on immobilized ni, hydrophobic interaction on phenyl-sepharose cl-4b and reverse-phase hplc. an 800-fold increase in specific activity and an overall recovery of 46% were achieved. the most effective step in its purification is the successful use o ... | 1985 | 3874789 |
| unusual features of sperm ultrastructure in the musk shrew suncus murinus. | the spermatozoon of the musk shrew suncus murinus displays unusual fine anatomical features. in the head, the equatorial segment of the acrosome is recessed within a waist in the sperm nucleus in a way that could afford some protection for this fusogenic region, perhaps during penetration of the egg vestments. the perinuclear material has distinctive inner and outer regions, the latter being arranged as a series of coxcomblike spikes. these structures in suncus could serve to anchor its characte ... | 1985 | 4056681 |
| light and transmission electron microscopic studies on the lingual dorsal epithelium of the musk shrew, suncus murinus. | 1985 | 4058838 | |
| a new retrovirus produced by tissue culture cell line from mammary tumor of a house musk shrew, suncus murinus. | a new type of retrovirus (sm-mtv) released by cultured cells of a spontaneous mammary tumor from a house musk shrew, suncus murinus, is described. the sm-mtv is distinct morphologically from type c particles. in spite of certain morphological similarities to type b and type d retroviruses, the sm-mtv is readily distinguishable. the extracellular virions had a spikeless envelope containing a centrally located nucleoid with a small electron-dense core surrounded by an inner membrane. the budding p ... | 1985 | 4060590 |
| pituitary luteinizing hormone level in the male house musk shrew, suncus murinus l., following castration and testosterone treatment. | the effect of castration and replacement therapy with testosterone propionate (tp) on the pituitary lh concentration and contents in the house musk shrew was investigated by using an in vitro bioassay for lh, the rat interstitial cell testosterone assay. the concentration and contents of lh increased slightly 10 days after castration, but decreased progressively thereafter to about a half of the pre-operation level by 90 days after the operation. the replacement with tp (100 micrograms/day) for ... | 1985 | 4085414 |
| lead haematoxylin-positive cells in the hypophysis of the musk shrew, suncus murinus l. (insectivora). | 1971 | 4108135 | |
| the pituitary gland of the musk shrew. suncus murinus l. (insectivora), with special reference to the cytology of the adenohypophysis. | 2011 | 4114309 | |
| histomorphology of the male accessory reproductive organs of suncus murinus sindensis anderson, the common indian shrew. | 1974 | 4139868 | |
| thyroid hormone secretion rate and biological half-life (t one half) of l-thyroxine-131 i in the musk shrew (suncus murinus). | 1969 | 4181507 | |
| localization of adenosine-tri-phosphatase and adenosine-5-phosphatase activities in the testes of indian desert gerbil and house shrew. | 1966 | 4228919 | |
| localization of non-specific phosphatases in the testes of meriones hurrianae jerdon, the indian desert gerbil, and suncus murinus sindensis anderson, the house shrew. | 1965 | 4284689 | |
| a comparative study on the localization of certain enzyme activities in the testes of the indian desert gerbil and the house shrew. | 1968 | 4299814 | |
| acth inhibition of dehydration-induced changes in the hypothalamic neurosecretory system of the musk shrew, suncus murinus l. | 1972 | 4350458 | |
| absence of salivary toxin in chhachhundar the indian shrew. suncus murinus. | 2013 | 4435943 | |
| certain biochemical observations on the testes and male sex accessory glands of two insectivores, suncus murinus sindensis anderson and hemiechinus auritus collaris gray. | 2015 | 4458380 | |
| inhibition by ethanol of dehydration-induced changes in the hypothalamic neurosecretory system of the musk shrew, suncus murinus l. | 1972 | 4537938 | |
| gonadectomy-induced histological changes in the hypothalamic neurosecretory system of the musk shrew, suncus murinus l. | 2016 | 4723196 | |
| body and peritesticular temperatures of musk shrews (suncus murinus). | 1974 | 4819319 | |
| the electrocardiogram (ecg) and impulse conducting system (ics) of the asian musk shrew, suncus murinus. | 1971 | 5101237 | |
| chromosome polymorphism in the malayan house shrew, suncus murinus (insectivora, soricidae). | 1971 | 5132609 | |
| enhanced growth and development of captive musk shrews, suncus murinus, on an improved diet. | 1971 | 5143697 |