Publications

cultivation of axenic entamoeba histolytica from small inocula.		1976	184038
entamoeba histolytica infection in a german shepherd dog.		1976	184910
[a patient with pain in her side].		1976	185532
ultrastructure of trophozoites of entamoeba histolytica from human amoebic liver abscess.		1976	185759
the epidemiology of amoebiasis--an hypothesis.		1976	185760
[the amebacidic properties of some 2-nitrobenzofuran substituants].		1976	185931
action of metabolic inhibitors on axenically grown entamoeba histolytica.		1976	186406
comparative susceptibility of latin american and united states students to enteric pathogens.		1976	186708
restoration of virulence to rat of axenically grown entamoeba histolytica by cholesterol and hamster liver passage.	a virulent strain of entamoeba histolytica (nih-200) from a symptomatic human case, cultured in vitro for more than three years, was unable to infect rat caecum or hamster liver. when grown with a mixed bacterial flora, it infected rat caecum but did not produce ulceration. after passaging amoebae growing with bacteria in hamster liver, amoebic hepatic lesions were regularly produced. the amoebae from liver lesions produced ulceration in the caeca of rats. expoxure to cholesterol of amoebae grow ...	1976	187128
[amebiasis. 1].		1976	187913
cellular sensitivity in amoebiasis--preliminary results of lymphocytic transformation in response to specific antigen and to mitogen in carrier and disease states.		1976	188212
[pharmacologic study of the amebicidal and trichomonicidal activity of ornidazole (1-(2-hydroxy-3-chloropropyl)-2-methyl-5-nitroimidazole].		1976	188370
drug and immuno-diagnostic resistant amoebic liver abscess in ibadan: an elucidation of a possible mechanism.	a thick fibrous walling of amoebic abscess of the liver is very rare. using as a basis the case of drug and immunodiagnostic resistant amoebic liver abscess in an adult nigerian, an account is given of the possible mechanisms for such therapeutic and diagnostic failure. a theory of blood-abscess cavity barrier is postulated and suggested as a mechanism for the constant failure to detect antibodies to e. histolytica in the small percentage of cases of amoebic liver abscess (morris, powell and els ...	1976	189058
virulence and toxicity of axenic entamoeba histolytica.		1977	189211
[possibilities and problems in the laboratory diagnosis of amebiasis].		1977	189237
[incidence of parasitic infestation by entamoeba histolytica in population samples in zaire evaluated in the laboratory by parasitologic and immunofluorescent methods].		1976	189706
selective ability of entomoeba histolytica to haemolyse red blood cells--a preliminary communication.		1976	190167
search for laredo type amoebae among entamoeba histolytica.		1976	190168
amoebiasis on easter island.		1976	190741
symposium on diarrhea. 3. investigation of chronic diarrhea.	the practical approach to the investigation of diarrhea must be logical and based on anatomic considerations. the site of the underlying disorder may be determined by the clinical picture, and the logic of investigation will be influenced by the history. important specific investigation in a case of colonic diarrhea include a careful rectal examination, stool inspection, sigmoidoscopy, rectal biopsy and barium enema study. colonoscopy has been used, but its role has yet to be defined. in a case ...	1977	191173
perforation of the colon in unsuspected amebic colitis: report of two cases.	two cases of amebic colitis that resulted in perforation of the colon, an ominous complication, are presented. the first was diagnosed preoperatively as acute ulcerative colitis with toxic megacolon, and the second as peritonitis complicating acute cholecystitis. in both instances the correct diagnosis was made after operation. the first patient recovered after colectomy and antiamebic therapy, but the second patient died in the early postoperative period, in septic shock. amebic colitis occurs ...	1977	191233
entamoeba histolytica: membrane fractions.		1977	191274
selective coeliac angiography in amebic liver abscess.		1977	191555
[fluorescent antibody technic as a diagnostic test in amebiasis].		1976	191740
cultivation of entamoeba histolytica as a diagnostic procedure: a brief review.		1977	191743
[diagnostic significance of identification of anti-entamoeba histolytica antibodies (author's transl)].	examinations were performed with the indirect immunofluorescence test (ifat) and the indirect haemagglutination test (ihat). negative titers (less than 1:5) do not exclude an infection with e. histolytica. titers up to 1:80 in both reactions are found in patients with negative stool specimens or indicate an asymptomatic infection of the intestinal lumen, an incipient or past symptomatic amoebiasis. ifat values of 1:160 together with a negative or positive ihat are also suggestive of the two last ...	1977	191745
parasitic infections in black children in an endemic schistosomiasis area in natal.	urine and stool specimens from 856 school children aged from 7 to 20 years, and from 80 preschool children, were examined for schistosoma haematobium and intestinal helminths and protozoa. s. haematobium was present in 57% with a peak of 81% in 13-14-year-old children. peak intensity preceded peak incidence and egg loads gradually decreased with age. there was no clear-cut difference between boys and girls with regard to intestinal parasites, nor was there a close correlation between the inciden ...	1977	191941
an in vitro model for measuring the cytopathic effect of entamoeba histolytica.		1977	192877
[immunofluorescence technic in the diagnosis of amebiasis].		1976	192988
[study of the antiprotozoal activity of compounds of the series of diphenyl ethers and certain nitrostyrols].		1976	192989
comparison of some methods for the detection of antigen-antibody reactions in amoebiasis.	the indirect hemagglutination test (iha) and counterimmuno-electrophoresis (cie) were used to test for antibodies to entamoeba histolytica in human sera using antigens from axenic cultures of the hk9 strain. correlation between the test was excellent with most sera from patients with amoebiasis demonstrating precipitin lines by cie at iha titers considered diagnostically positive, larger than or equal to 1:128. precipitin reactions with positive sera were also compared by cie, immunoelectrophore ...	1976	193204
[the origin of histological changes in amebiasis].	on microscopic examination of histological specimens from an autopsy case with severe amoebiasis, extensive ulcerative-necrotic lesions in the colon were found associated with an amoebic peritonitis and severe degenerative lesions of the ganglion-cells of the plexus myentericus induced by entamoeba histolytica. there was also an infiltration of a mesenteric lymphnode by amoebae carried by the lymph through the vasa afferentiae lymphaticae. in the liver several granulomas (amoebic granulomas) and ...	1977	193418
entamoeba histolytica: autoradiographic analysis of nuclear sites of rna synthesis.		1977	193710
effect of storage, different media constituents and dilution of axenic medium on the growth of axenic culture of entamoeba histolytica.		1977	193783
isolation of enteric pathogens from asymptomatic students from the united states and latin america.		1977	193996
actin in entamoeba histolytica trophozoites revealed by human actin antibodies.		1977	194025
[clinical aspects of amebiasis].		1977	194302
[biological diagnosis of malaria and amebiasis].		1977	194303
definition of the antigenic pattern of entamoeba histolytica, and immunoelectrophoretic analysis of the variation of patient response to amebic disease.	the antigenic anatomy of entamoeba histolytica and the variation in response of 148 patients with amebic disease are described. immunoelectrophoretic patterns and indirect hemagglutination titers were studied in sera obtained from patients with amebic disease acquired in several areas of the world, i.e. canada, vietnam, afric, india, central america, and southern united states. the various populations are compared and similarities and differences are discussed.	1977	194490
experimental amebiasis. i. pathogenicity of axenically cultured entamoeba histolytica in the brain of the newborn mouse.	axenically cultured entamoeba histolytica inoculated intracerebrally into newborn swiss mice invaded the cerebrum and produced multiple abscesses containing viable trophozoites. as few as 20 amebae of a virulent strain (hm-1:imss) occasionally produced fatal disease, 200 killed about 75% of animals and higher doses regularly killed all animals. in contrast, avirulent strains (hk-9 and hb-301:nih) failed to produce acute brain disease in comparable time periods even when mice were inoculated with ...	1977	194491
experimental amebiasis. ii. hepatic amebiasis in the newborn hamster.	newborn hamsters inoculated intrahepatically were highly susceptible to infection by axenically cultured entamoeba histolytica. inoculations were performed through the abdominal wall, and lesions could be observed through the skin as early as 4 days after inoculation. the most virulent amebal strain, hm-1:imss, produced liver lesions in 19% of newborn animals inoculated with 20 amebae, and in about 90% receiving 2,000 amebae. eleven other strains similarly tested either produced no lesions with ...	1977	194492
invasive amebiasis. i. amebic dysentery and its complications.		1977	195178
1,4-bis-[1-methyl-5-nitroimidazolyl-(2-methyleneimino)]-piperazine, a new drug with marked activity against entamoeba histolytica. short communication.	1,4-bis-[1-methyl-5-nitroimidazolyl-(2-methyleneimino)]-piperazine (hoe 316) administered orally produces an effect which is clearly superior to that of metronidazole against entamoeba histolytica in the golden hamster and slightly inferior against trichomonas fetus and t. vaginalis in the mouse. the acute tolerance of the compound is very good (ld 50% greater than 10 g/kg body weight). it is assumed that the possible main metabolite of hoe 316 is a monohydrazone: 1-methyl-2-(4-amino-piperazino- ...	1977	195590
some reactions in which inorganic pyrophosphate replaces atp and serves as a source of energy.		1977	195842
[new diagnostic methods for the early diagnosis of amebic liver abscesses].		1976	196432
entamoeba histolytica: localization and characterization of phosphorylase and particulate glycogen.		1977	196880
entamoeba histolytica: localization and characterization of phosphoglucomutase, uridine diphosphate glucose pyrophosphorylase, and glycogen synthase.		1977	196881
[imidazoles in the treatment of infections due to parasitic protozoa "lumenals". (t. vaginalis, giardia intestinalis, e. histolytica--general principles)].		1976	196967
viruses of entamoeba histolytica. vii. novel beaded virus.	a third amoebal virus type was isolated from four different strains of entamoeba histolytica. the virus was most frequently seen as a linear structure about 235 nm long and consisting of 14 beadlike structures about 19 nm in diameter. a "dimer" of twice the length and consisting of 28 beads was occationally encountered. the virus replicated in the nucleus, forming ordered arrays. acridine orange staining of viral aggregates in infected nuclei suggested the presence of double-stranded nucleic aci ...	1977	197265
amebiasis. an increasing problem among homosexuals in new york city.	during a five-year period at the new york hospital, entamoeba histolytica was identified in the stools of 20 men who had not traveled outside the new york area. all of the patients were found subsequently to homosexual. during this same period amebiasis was diagnosed in 30 men who had traveled; only two were homosexual. of ten patients with e histolytica infection seen during the first year of this study, none were homosexual whereas eight of 11 patients in the fifth year were homosexual, sugges ...	1977	197276
venereal transmission of enteric pathogens in male homosexuals. two case reports.	in two cases there was simultaneous or sequential occurrence of amebiasis, shigellosis, and giardiasis in male homosexuals. enteric pathogens may, under the proper conditions, be venereally transmitted. in particular, the sexual practices of male homosexuals, most significantly, oral-anal contact, appear to provide the necesseary link for transmission. evidence suggests that this is a growing problem.	1977	197277
[ameboma of the cecum].		1977	197436
studies on the prevalence of entamoeba histolytica in iraq.		1976	198048
amebic granuloma--an experimental study.	the etiopathogenesis of granuloma formation in amebiasis is not known. an experimental study was carried out in 48 guinea pigs arranged into four groups, to assess the role of hypersensitivity in formation of amebic granuloma. repeated intracecal inoculations of saline in group i and mixed amebic and bacterial suspension in other groups were made. animals in group iii were sensitized by amebic antigen and in group iv by bacterial antigen before inoculations. lesions produced in the amebic hypers ...	1977	199058
[cytochemical labeling of proteolytic enzymes in entamoeba histolytica].	trophozoites were obtained from fecal mucous in patients bearing colonic amebiasis. the tripsin inhibitor of soya bean was coupled to peroxidase according to nakane and kawokoi method. amebae were incubated with couple and reactions were developed following karnowsky's technic. there was a specific labeling of proteolitic enzymes on plasma membrane, the wall of digestive vacuoles and intracytoplasmic vacuoles of the trophozoites. such a distribution of proteolitic enzymes agreed with digestive a ...	1977	199123
amoebic serology vs appendicular lumps.		1977	199568
[amebic abcess of the liver analysis of 7 cases (author's transl)].		1977	199928
[invading intestinal amebiasis in infants (author's transl)].		1977	199929
qualitative x-ray spectrometric study of e. histolytica trophozoite nuclei.	qualitative x-ray energy spectroscopical analysis was performed in two strains of entamoeba histolytica trophozoites: hk-9; nih strain, and hm-2; imss strain, cultured in axenic and monoxenic conditions, respectively. the trophozoites were fixed in buffered-glutaraldehyde, embedded in epon, thick sectioned )50-200 nm), and mounted on nickel grids. x-ray emissions were analyzed with an ortec x-ray energy detector and multichannel and analyzer adapted to a transmission electron microscope. the stu ...	1977	200194
[chemical and pharmacologic study on pyran derivatives. ix. synthesis of 2-dialkylaminochromones].	under suitable conditions the reaction of phenol and n,n-dialkylethoxycarbonylacetamides, in the presence of phosphorus oxychloride, resulted in the formation of 2-dialkylaminochromones. in a similar manner, variously substituted phenols afforded 2-dialkylaminochromones with substituents in different positions of the benzene ring. pharmacological screening of all these compounds showed that they markedly affect the cns, activity being mainly excitatory. decreased activity was shown by compounds ...	1977	200470
surface features of entamoeba histolytica and rabbit kidney (rk13) cell surface changes after trophozoite contact--observations by scanning electron microscopy.		1977	200580
[synthesis and amoebicid properties of emetin analogs. analysis of the new compounds by 13c-nmr. b/c-cis or trans-fused (+/-) 1-alkyl-3-desethyl-emetin (author's transl)].		1977	200588
[value of sensitization of adult albino rats with amebic antigen before their inoculation with the culture of entamoeba histolytica].		1977	200834
amebic balanitis.		1978	201784
current concepts in parasitology. amebiasis.		1978	201844
the epidemiology of infection with entamoeba histolytica in the gambia, west africa.	a country-wide stool survey of the gambia showed the prevalence of entamoeba histolytica cysts to range from 13.7% up-country in the dry season to 52.3% near the coast. a longitudinal survey showed a near 100% infection rate over one year and a sharp rise in prevalence as the rains commence with an equally sharp fall as the rains progress. specific antibody levels are elevated and reasonably constant through the year. carriers generally show no specific lymphocyte reactivity to amoebic antigen b ...	1977	202045
amoebiasis and intestinal parasitic infections in a population on cebu island, the philippines.		1977	202206
entamoeba histolytica and entamoeba invadens: chromium release from labeled human liver cells in culture.		1977	202477
isolation and maintenance of a strain of entamoeba histolytica schaudinn, 1903 and the possibility of its utilization in screening of drugs.		1977	203016
chemotherapeutically active nitro compounds. 4. 5-nitroimidazoles (part i).	more than 135 new 2-methyl-5-nitroimidazoles substituted in 1-position and 1-methyl-5-nitroimidazoles substituted in 2-position were investigated for their activity against various protozoan species, in particular entamoeba histolytica in the golden hamster, trichomonas fetus, trypanosoma brucei and t. cruzi in the nmri mouse. among the nitroimidazoles substituted in the 1-position only two preparations exhibited a similar effect as metronidazole preparations exhibited a similar effect as metron ...	1977	203293
amoebiasis.		1978	203420
bisamidines of 2,6-diaminoanthraquinone as antiamebic agents.	a series of bisamidines of 2,6-diaminoanthraquinone was synthesized and tested against cecal and hepatic forms of entamoeba histolytica infections in rats and hamsters, respectively. a number of compounds were found to have good activity against infections in both species.	1978	203694
structural changes on entamoeba histolytica trophozoites after cryopreservation in liquid nitrogen.	trophozoites of entamoeba histolytica cultures which had been deep-frozen in the presence of 5% dmso, along with untreated cells and cells treated with dmso (5%), were examined for fine-structural changes. after deep-freezing in liquid nitrogen only a few amoebae exhibited normal nuclear and cytoplasmic structure. one frequently observed but unspecific finding pertaining to recovered cells is the separation of the cytoplasm into large vacuolated (coarse-granular) and electron-optically fine-gran ...	1977	204119
[the enzyme-linked immunosorbent assay (elisa) in the diagnosis of amoebiasis (author's transl)].	an enzyme-linked immunosorbent assay (elisa) technique as an aid to the detection of antibodies to entamoeba histolytica has been evaluated in four groups of 39 individuals. results were positive in 15 patients with amoebic dysentery harboring trophozoites of entamoeba histolytica, in their stools; negative in 6 patients with enteric symptoms whose faeces contained neither trophozoites nor cysts of entamoeba histolytica, in 8 patients with other parasitic diseases in whom clinical examination wa ...	1977	204261
latex agglutination test for amoebiasis in pakistani patients with chronic 'obscure' liver enlargements.	the latex agglutination test for amoebiasis was done in 50 pakistani patients in whom a clinical diagnosis of chronic non-supparative amoebic hepatitis was made on the basis of liver enlargement associated with chronic recurrent abdominal disturbance. the serological test was negative in 32 (64%) and positive in 18 (36%). examination of stool specimens showed a higher frequency of e. histolytica in serology positive patients. the liver biopsy findings were variable and included normal histology ...	1978	204801
[pathogenesis of amebiasis. 1. clinical aspects of amebiasis in brazil. study of 3 groups of population of 3 different geographic regions].		1977	204979
cytotoxic activity of a cell-free extract of entamoeba histolytica.		1978	205017
a new technique of heterogenous enzyme-linked immunosorbent assay, stick-elisa. ii. application of stick-elisa to antigens of various infective agents.	stick-enzyme-linked immunosorbent assay (stick-elisa) was applied to antigens of a variety of infective agents. an acceptable reproducibility in a series was reached, the variation coefficient being twelve percent. preliminary results revealed that ready coated sticks could be stored at 4 degrees c for at least two to three weeks.	1978	205062
[amoebas with special reference to entaboeba histolytica. symptomatology, diagnosis and results of a survey conducted in huambo, angola].		1976	205139
[intraperitoneal rupture of an amebic liver abscess. apropos of a clinical case].		1976	205140
[amebic liver abscess draining into the pericardium. report of a case with favorable outcome].		1977	205181
amebic peritonitis following rupture of an amebic liver abscess. successful treatment of two patients.	we present two successfully treated cases of amebic peritonitis. acute peritonitis secondary to intra-abdominal rupture of an amebic liver abscess is an infrequent but serious complication of invasive amebiasis. its diagnosis should be considered in anyone with a suspected liver abscess, jaundice, or diarrhea in whom peritonitis develops. this diagnosis should be further suggested in the united states if the patient is a male and is of mexican origin in areas where this racial group constitutes ...	1978	205190
pathogenicity of entamoeba histolytica--virulence of strains of amoebae from symptomatic and asymptomatic cases of amoebiasis.		1977	205504
behavior of axenic ip-106 strain of entamoeba histolytica in the golden hamster.	strain ip-106 of entamoeba histolytica was isolated 12 yr ago from a case of amebic dysentery and has been maintained in axenic culture for the past 11 yr. hamsters were inoculated intrahepatically, intraperitoneally, and intracecally with 6.5, 5.0, and 8.0 x 10(4) axenic trophozoites, respectively. with the first two routes of inoculation all the animals developed liver abscesses, and most developed amebic metastases to other sites. after intracecal inoculation only 3 out of 6 animals developed ...	1978	206159
effect of hamster liver passage on the virulence of axenically cultivated entamoeba histolytica.		1978	206160
[persistency of serum antibodies against entamoeba histolytica].	with the purpose to determine the duration of serum antibodies against e. histolytica by means of the contraimmunoelectrophoresis technique, 31 patients with the diagnosis of intestinal or liver invasive amebiasis were included in this study. in 92.3% of the 13 patients subjected to transversal study, no specific antibodies were found from 10 to 24 months after the occurrence of amebic disease. in 64.7% of 17 children with liver amebiasis who were studied longitudinally, no serum antibodies were ...	1978	206270
[cytolytic immunreactions in vitro against trophozoites of e. histolytica (author's transl)].		1978	206512
new indolic cysticidal agents.	from a series of compounds having amino acid esters linked into the 3 position of substituted indole 3-acetic acids only the compounds 2 and 6 have shown promizing biological activity where as compound 2 process excystment property only, compound 6 has shown both excystment and cysticidal properties. all other compounds are inactive.	1977	206917
[pathogenesis of amebiasis. ii. endoscopy and histopathology of the rectosigmoid mucosa in intestinal amebiasis].		1977	206948
[pathogenesis of amebiasis. iii. serological tests in patients infected with entamoeba histolitica].		1977	206949
[factors involved in the spread of enteroparasites. iii. distribution of various enteroparasitosis in 2 population groups in the city of ribeirão preto, são paulo, brazil].		1978	206950
haematogenous amoebic lung abscess. a case report.	left upper lobe amoebic lung abscess without established hepatic amoebiasis in a young black man is described and the pathogenesis is briefly discussed.	1978	206979
electrophoretic isoenzyme patterns of entamoeba histolytica and entamoeba coli.	cultures of 14 stocks of entamoeba histolytica and one only of entamoeba coli were compared by electrophoretic patterns of three enzymes: glucose-phosphate isomerase, phosphoglucomutase and l-malate: nadp+ oxidoreductase (oxaloacetate-decarboxylating). easily distinguished patterns divided e. histolytica into three groups, whilst a distinctly different pattern for e. coli was also seen.	1978	206991
a simple technique for preparing clone cultures of entamoeba histolytica.		1978	206992
entamoeba histolytica and homo sapiens.	blind acceptance of the dicta of the great has led to much confusion as to the relationship between amoeba and man. a review of the mistakes of the past may lead to a better appreciation of the present, and higher hopes for the future. an hypothesis is presented.	1978	207506
entamoeba histolytica, e. invadens, and e. moshkovskii: fluctuations of the dna content of axenic trophozoites.		1978	207550
detection & characterization of humoral antibodies from amebic immune sera.		1977	207638
presence of prostaglandins a & e in entamoeba hystolytica.		1977	207640
synthesis and amoebicidal activity of novel substituted quinolines.		1978	207641
[update on amebiasis. physiopathology].		1978	208130