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dietary practices and cancer mortality in china.an ecological survey on diet, life style and cancer mortality was carried out in 65 rural counties in china, using a questionnaire comprising 285 questions on environmental factors, dietary practices and other life style characteristics; in addition, blood, urine and food were collected and analysed. two interpretations of preliminary data are presented. one is for the finding of a positive correlation between a latent variable, namely general nutritional status, and cancer mortality rates; the ...20071855846
perinatal development of hepatic cholesterol synthesis in the rat.rates of cholesterol synthesis and hmg coa reductase activity in rat liver, have been reported to be high before and low after birth. the timing of the decline in perinatal rates of cholesterol synthesis, however, is uncertain. these studies, therefore, determined in vivo rates of cholesterol synthesis using [3h]water and hepatic reductase activity in vitro in perinatal rats. the lipid composition of the plasma, liver and its microsomal subfraction were also determined. reductase activity increa ...19911892876
role of magnesium in the dietary cation-anion balance equation for ruminants.eight midlactation holstein cows (four primiparous) were assigned to replicated 4 x 4 latin squares with a 2 x 2 factorial arrangement of treatments. the basal diet was formulated to contain 0 milliequivalents (na + k) - cl/100 g of diet dm. treatment diets of high and low dietary cation-anion balance were achieved by adding appropriate amounts of supplemental na + k (added on an equivalent basis) or mg to the basal diet. milk and protein yield were increased as well as dmi and fcm for na + k di ...19911894796
oligonucleotide-directed mutagenesis of psbb, the gene encoding cp47, employing a deletion mutant strain of the cyanobacterium synechocystis sp. pcc 6803.a mutant strain of the cyanobacterium synechocystis sp. pcc (pasteur culture collection) 6803 has been developed in which psbb, the gene coding for the chlorophyl alpha-binding protein cp47 in photosystem ii (psii), has been deleted. this deletion mutant can be used for the reintroduction of modified psbb into the cyanobacterium. to study the role of a large hydrophilic region in cp47, presumably located on the lumenal side of the thylakoid membrane between the fifth and sixth membrane-spanning ...19911932693
imaging of the temporomandibular joint in rheumatic disease. 20071932821
asymptomatic patients with hiv infection. keeping them well.primary care physicians need to be prepared to counsel and manage patients with human immunodeficiency virus (hiv) infection. asymptomatic seropositive patients should be seen quarterly, and t4 lymphocyte counts should be followed. other serologic markers that may detect disease progression are p24 antigen and beta 2 microglobulin. abnormalities in the levels of these markers may influence the decision to initiate early antiretroviral therapy. therapeutic regimens are now available for delaying ...19901971717
laboratory information systems from a perspective of continuing evolution.during the past 20 years, laboratory systems have evolved to a high degree of complexity. in some cases, continuing addition of new features has adversely affected functionality. there is increasing recognition that the number of features listed on a request for proposal does not necessarily provide an accurate guide to functionality in day to day operations.20072040150
[screening and follow-up of patients with arteriopathies of the lower limbs using the test proposed by laing].the authors tested a standard exercise suggested by laing in 1980 for the screening and the follow-up of patients with atherosclerotic lesions of the arteries of the lower limbs. were included in this study 44 patients with monolateral symptoms and was studied the asymptomatic limb. the results were compared with the ones obtained by the traditional exercise proposed by strandness and with the ones of a control group studied with the two tests. the excellent correlation of the data gives us the ...20072074933
[2 cases of a combination of arterial and arteriovenous cerebellar aneurysms]. 20072168653
metabolism of oestradiol-17 beta and progesterone in the white rhinoceros (ceratotherium simum simum).14c-labelled oestradiol-17 beta and progesterone (50 mu ci each) were injected i.v. into an adult female white rhinoceros and all urine and faeces collected separately over the next 4 days. the total recovery of injected label was 61%, 25% being present in the urine and 36% in the faeces. of the radioactivity recovered, 69% was excreted on day 2 of the collection period. repeated extraction of samples obtained on day 2 showed that, of the radioactivity in faeces, 92.4% was associated with unconj ...20072174460
hypoglycemia risk during exercise after intramuscular injection of insulin in thigh in iddm.the influence of bicycle exercise (60% of w170 [working capacity at a pulse rate of 170 beats/min]; 40 min) on the absorption of 125i-labeled fast-acting insulin (10 u; actrapid human insulin) after intramuscular compared with subcutaneous injection in the thigh was studied on 2 consecutive days in 10 insulin-dependent diabetes mellitus (iddm) patients. insulin absorption was measured as disappearance of radioactivity (1st-order elimination rate constants) by continuous external monitoring and a ...19902190773
desferrioxamine provocative test: methodology for estimating iron and total iron binding capacity. 20062242435
self-injury in psychiatric in-patients.suicide and self-injury in-patients were identified on the basis of a retrospective content analysis of special incidence reports completed the preceding year at an urban state psychiatric hospital. select clinical and biodemographic variables were then examined, and in order to determine the importance of these variables in the prediction of incident severity, a multiple regression analysis was performed. schizophrenic patients were found to be significantly over-represented among both the self ...20082246100
[secretory gm3 sialidase during the cell growth]. 20072258655
[secretory gm3 sialidase during the cell growth]. 20072258655
lamp-1 in cho cells is a primary carrier of poly-n-acetyllactosamine chains and is bound preferentially by a mammalian s-type lectin.recent studies indicate that some mammalian s-type lectins bind preferentially to oligosaccharides containing the repeating disaccharide [3gal beta 1,4glcnac beta 1]n or poly-n-acetyllactosamine (pl) sequence. we report here our investigation on the distribution of these sequences in glycoproteins in chinese hamster ovary (cho) cells and the interaction of glycoproteins containing pl chains with an immobilized s-type lectin (l14) from calf heart tissue. our results demonstrate that pl chains are ...20082268316
purification and fractionation of lipopolysaccharide from gram-negative bacteria by hydrophobic interaction chromatography.by hydrophobic interaction chromatography on octyl-sepharose, lipopolysaccharide (lps) of escherichia coli re mutant and of wild-type smooth-form (s-form) salmonella typhimurium and salmonella abortus equi is fractionated according to increasing amount of fatty acids. thereby a fractionation of s-form lps according to the length of the o-polysaccharide chain also occurs, because with increasing of fatty acids there is a decrease in the mean length of the o-polysaccharide chain from approximately ...19902269290
the surgeon's scissor-jaw reflex. 20082279161
a sensitive and specific liquid-chromatographic assay for determination of ganciclovir in plasma and urine and its application to pharmacokinetic studies in the rabbit.a liquid-chromatographic assay for the analysis of ganciclovir in plasma and urine is described. this assay involves the use of acyclovir, an antiviral drug structurally related to ganciclovir, as the internal standard. a two-step sample preparation method is used. after protein is precipitated with acetonitrile and the addition of diethyl ether, ganciclovir and the internal standard are back extracted into a small volume of aqueous ammonium phosphate, taking advantage of their relatively high w ...19902293208
[immunity status of 2 chilean female populations against rubella].a total of 1248 females were studied to determine immunity against rubella. a higher socio-economic subgroup (n = 789) and a lower one (459) were defined. inhibition of hemagglutination was used to detect immunity. positive results were obtained in 95% of females and no differences were detected for both groups. 78% of positive titers fell in the dilution range 1:20 to 1:80.19902293267
exploring subjective vs. objective issues in the validation of computer-based critiquing advice.evaluation is an important part of the development of computer-based medical expert systems. such evaluation may be particularly difficult when judging a critiquing system which responds to a proposed management strategy with a discussion of the advisability of that approach. dxcon is an expert system which produces a prose critique discussing the radiologic workup of obstructive jaundice. this paper describes dxcon, and its experimental validation by three independent judges. a central componen ...20082311365
nucleotide sequence of porcine insulin-like growth factor. 1:5' untranslated region, exons 1 and 2 and mrna. 19902326169
the 5'- and 3'-untranslated regions of ornithine decarboxylase mrna affect the translational efficiency.we have determined the roles of the 5'- and 3'-untranslated regions (utr) of ornithine decarboxylase (odc) mrna in the post-transcriptional regulation of this enzyme. a series of expression vectors were constructed in which portions of the odc 5' and/or 3' utrs were placed flanking a reporter gene coding sequence, either firefly luciferase or chloramphenicol acetyltransferase, so as to generate a hybrid transcript. translation of these chimeric genes in transient expression assays in wild type a ...19902365700
[initial expiratory activity as one of the criteria of the respiratory center function].in 13 healthy men at rest and dosed muscular loads the authors studied maximal rates of the mouth pressure at the onset of inhalation and expiration (dp/dti, dp/dte) as well as the respiratory pattern. the parameter dp/dte positively correlated with that of dp/dti which reflects, as is known, an inspiratory activity of the respiratory center. the authors think that dp/dte parameter can be used for noninvasive determination of expiratory activity.20082386815
a comparison of anthropometry with computed tomography in limbs of young and aged men.arm and leg composition determined by anthropometry (ap, girths, and skinfolds) were compared with computed tomography (ct) in 7 young (mean age 31.4y) and 13 old (74.8y) males. five transverse ct scans, girths, and skinfold measurements were made. in each ct image, total cross-sectional area (csa), bone csa, muscle compartment csa, and "pure" muscle csa within the compartment were measured. corresponding volumes were also calculated. total limb and muscle plus bone csa and volumes were estimate ...20082394914
neurodevelopmental assessment after congenital cytomegalovirus infection.the neurodevelopmental state of 41 children with congenital cytomegalovirus infection and their controls was assessed at 2 years using the griffiths scale. the scores achieved by children with congenital cytomegalovirus but with no associated neurological abnormality (asymptomatic) were similar to those of the control children, whereas the mean score of the five children with congenital infection and neurological impairment (symptomatic) was significantly lower. this study, which has the statist ...19862423040
a role for exon sequences and splice-site proximity in splice-site selection.analysis of the in vitro splicing products of rna precursors containing tandem duplications of the 5' or 3' splice sites of human beta-globin ivs 1 revealed that exon sequences play an important role in the relative use of the duplicated sites. these studies also show that the proximity of the 5' and 3' splice sites is an important determinant in the selection of splice-sites. deletion, substitution, or even subtle changes of exon sequences can alter the pattern of splice-site selection, and in ...19862427200
a mucin containing the x, y, and h type 2 carbohydrate determinants is shed by carcinoma cells.monoclonal antibody br 15-6a directed to the y carbohydrate determinant (fuc alpha 1----2gal beta 1----4glcnac(3----1fuc) beta 1----3gal beta 1----4glc beta 1----1cer) reacted with the cell surface and conditioned media of colorectal and breast carcinoma cell lines. double determinant immunoassays using br 15-6a as detector antibody showed that the y determinant is part of a high molecular weight mucin that coexpressed other carbohydrate antigens based on a type 2 chain (x, h type 2). type 1 cha ...20082442094
subretinal neovascular membranes associated with choroidal nonperfusion and retinal ischemia.this is the first well-documented case of co-existent underlying choroidal nonperfusion in an eye with a subretinal neovascular membrane that was subsequently treated with krypton red laser photocoagulation by the senior author (lem). the possible role of chronic macular ischemia secondary to choroidal circulatory impairment is discussed in relationship to other well-established risk factors. perhaps treatment to improve macular oxygenation would be a reasonable alternative to eradication of the ...20052446561
subretinal neovascular membranes associated with choroidal nonperfusion and retinal ischemia.this is the first well-documented case of co-existent underlying choroidal nonperfusion in an eye with a subretinal neovascular membrane that was subsequently treated with krypton red laser photocoagulation by the senior author (lem). the possible role of chronic macular ischemia secondary to choroidal circulatory impairment is discussed in relationship to other well-established risk factors. perhaps treatment to improve macular oxygenation would be a reasonable alternative to eradication of the ...20052446561
sexual assault centre, auckland, new zealand.in 1982 a sexual assault centre was established in central auckland. its history, philosophy and structure are described. services to sexual assault victims are outlined. of particular interest is the sexual abuse team, comprising a triad of specifically trained staff from the police, department of social welfare and the sexual abuse centre. the auckland centre has served as a prototype for centres in other regions of new zealand.20082516213
bites and stings. part 2. bees and vespids. 20082519523
effects of maximal breath holding on maximal expiratory flows.effects of breath holdings (bh) on bronchomotor tone, maintained until their breaking points, have been studied using maximal expiratory flow volume curves (mefvc). bhs have been performed either at high lung volume (total lung capacity, eibh) or at low lung volume (residual volume +250 ml, eebh), an inspiratory manoeuvre immediately preceding the mefvc. the results show that: (1) eibh induces a significant increase of expiratory flow at 25% of fvc; (2) eebh induces a significant and constant de ...20082525484
subtype-specific increase in g-protein alpha-subunit mrna by interleukin 1 beta.the guanine nucleotide regulatory proteins (g-proteins) which are substrates for adp-ribosylation by pertussis toxin (alpha i-1, alpha i-2, alpha i-3 and alpha o) transduce a variety of hormonal signals. endothelial cells express mrna for three alpha i subtypes although the level of alpha i-1 mrna is very low. interleukin 1 beta (il 1 beta), a pleiotropic inflammatory mediator which stimulates a complex series of responses in human endothelial cells leading to increased coagulation and platelet ...19892525485
an epidemiological study of children's attitudes toward disability.in this epidemiological study the authors recorded the attitudes of children in hamilton, ontario, to physically disabled and mentally handicapped children. univariate analyses confirmed the importance of female gender, friendship and contact with handicapped persons as determinants of more accepting attitudes. type of disability and the presence or absence of disabled children in respondents' schools were not found to influence attitudes in a systematic manner. correlations between attitudes an ...20082525495
circadian variation in myocardial ischemia: the 24-hour antianginal effect of amlodipine. proceedings of a symposium. monte carlo, monaco, april 7, 1989. 20082530865
[public health-microbiological evaluation of housekeeping combinations for cleaning and disinfecting bed pans in the hospital].for prophylaxis of infection in hospital and for staff care protection the bed pans used by hospital patients should be disinfected. nowadays this is done mostly thermically in automatic disinfection systems. in germany there is no regulation for the hygienic-microbiological check-up of these machines. the routine testing method for disinfection machines of bed pans is demonstrated. under hygienic-microbiological aspects the technical procedures in disinfection machines are described and explain ...20082532724
co2 laser laparoscopic surgery. adhesiolysis, salpingostomy, laser uterine nerve ablation and tubal pregnancy.used endoscopically, the co2 laser offers some advantages over other operative techniques for endometriosis and adhesions but, in spite of the continuing development of new instrumentation there are still problems with the system. the technique needs specialized equipment requiring ongoing biomedical maintenance and specialized technical care in the operating room. some problems such as the intraperitoneal accumulation of smoke, gas leakage, and difficulty with maintenance of proper beam alignme ...19892533009
adenylate kinase of mycobacterium marinum. amino acid composition, secondary structure and other aspects.1. adenylate kinase purified from mycobacterium marinum shares homology with the enzyme from mammalian muscle and from other bacteria with respect to amino acid composition, total residues and mr. 2. however, it differs from others in not containing a free sulfhydryl or disulfide group. 3. it is much more sensitive to inhibition by adenosine (5')pentaphospho(5')adenosine than is the enzyme from other sources. 4. the enzyme contains 24% alpha-helix, 30% beta-structure and 46% random coil.19892551753
replicative and cytopathic characteristics of hiv-2 and severity of infection. 19892564945
adherence kinetics of haemophilus influenzae type b to eucaryotic cells.haemophilus influenzae type b (hib) adhere in vitro to buccal epithelial cells (bec) via pili (fimbriae). in vivo studies have conflicting lines of evidence concerning the role of pili in adherence. this study characterizes the kinetics of hib binding to bec and compares pilus versus nonpilus adherence. adherence was assessed using radioactive, immunofluorescence, and electron microscopic techniques. paired hib strains were obtained from three children with hib meningitis; piliated hib were isol ...19892573033
adherence kinetics of haemophilus influenzae type b to eucaryotic cells.haemophilus influenzae type b (hib) adhere in vitro to buccal epithelial cells (bec) via pili (fimbriae). in vivo studies have conflicting lines of evidence concerning the role of pili in adherence. this study characterizes the kinetics of hib binding to bec and compares pilus versus nonpilus adherence. adherence was assessed using radioactive, immunofluorescence, and electron microscopic techniques. paired hib strains were obtained from three children with hib meningitis; piliated hib were isol ...19892573033
[undescended testis--a review].according to registrations in several countries far too many retractile testes are falsely included in patient materials of truly undescended testes. the problem of overtreatment is so great that even with a low frequency of complications to the treatment, the netto effect on the population's fertility may become negative. the most important task for the clinician is to discern truly undescended from retractile testes. the decision has to be based on thorough clinical examination, but ultrasonog ...20062573036
detection of minority point mutations by modified pcr technique: a new approach for a sensitive diagnosis of tumor-progression markers.the detection of point mutations correlated with diseases, in enzymatically amplified dna sequences (polymerase chain reaction), is currently performed by digestion of pcr products when an existing restriction site disappears at least in one allele of the amplified mutated sequence or by allele specific radiolabeled probes in all other cases. these methods are the most sensitive but they cannot detect a mutation if it is present in less than 5% of the studied cells. we describe here a method bas ...19892573037
[intrathecal perfusion of acnu neurotoxicity and intrathecal pharmacokinetics in dogs].we studied the feasibility of intrathecal acnu perfusion therapy against subarachnoid dissemination of malignant glioma. intrathecal perfusion was performed in adult dogs by constant drip administration of 1 to 2 mg acnu dissolved in 10 to 20 ml of lactate ringer solution into the lateral ventricle and cerebrospinal fluid drainage through the lumbar puncture. the perfusion time was changed from 15 to 71 min. a bolus injection of 2 mg acnu was also tested in one dog. no neurological symptom was n ...19892586715
[chronic subdural hematoma following advanced cancer: report of three cases].three cases of chronic subdural hematoma (csh) following advanced cancer are reported. case 1. a 54-year-old male patient was referred to our clinic in a semicomatose state. bilateral csh was evacuated through a pair of burr holes, and consciousness was recovered. however, subependymal hemorrhage occurred at the third ventricle 6 days after the operation. hematological examination revealed thrombocytopenia. he died 12 days after operation because of hemorrhage in the lung. postmortem examination ...20082586717
protein kinase c regulates the tonic but not the phasic component of contraction in guinea-pig ileum.1. we have investigated the effect of phorbol esters and the down-regulation of protein kinase c on contraction of guinea-pig ileum longitudinal smooth muscle to carbachol and high k+. 2. phorbol 12,13-dibutyrate (pdbu) enhanced the phasic component and inhibited or enhanced, respectively, the tonic component of contraction to carbachol and high k+. in contrast, 4 alpha-phorbol, which does not activate protein kinase c, had no effect on these responses. 3. exposure to phorbol 12-myristate 13-ace ...19892590770
tumor markers of lung cancer: carcinoembryonic antigen and tumark.to assess the value of tumor marker determinations in diagnosing lung cancer and monitoring the response to therapy in lung cancer patients, we tested the serum concentration of tumark-reactive protein and carcinoembryonic antigen (cea) in 78 patients with lung cancer and 81 patients with non-malignant diseases. the sensitivity of tumark in detecting the presence of lung cancer was 63.8%, compared to 37.2% for cea (p less than 0.05). the specificity was 91.3% for tumark and 97.5% for cea. the co ...20082592942
[coagulation and fibrinolysis associated with contact phase in plasma with high molecular weight kininogen deficiency].congenital deficiency of high molecular weight kininogen (hmwk), first reported by saito et al. in 1975, is a rare disorder with homozygous defect of hmwk and only 14 cases have been reported so far. prolonged partial thromboplastin time and depressed intrinsic fibrinolytic activity in plasma interacted with negatively charged surface were characterized in these patients without any bleeding problem. on the other hand, patients associated with hemorrhagic disorder, such as haemophiliacs, showed ...19892593236
granulopoiesis in tadpoles of rana esculenta. ultrastructural observations on the morphology and development of heterophil and basophil granules.the morphology and development of heterophil and basophil granules from the trunk kidneys of rana esculenta tadpoles were studied at the electron microscopic level. cells of the heterophils series contain granules displaying either spheroid profiles with homogeneous content (type a), or elongate profiles with a crystalloid interior (type b). type a granules apparently originate directly from golgi-derived vesicles, which, gaining slightly in size and density, transform into the mature granules. ...20082606765
aberrant intratympanic internal carotid artery: a potentially hazardous anomaly.a case is presented of a 3-year-old girl with no previous history of ear disease or developmental defects who bled profusely upon (right) myringotomy. the haemorrhage could only be stopped with the aid of an ear insert and a nasopharyngeal balloon catheter. the balloon catheter was removed the following day but the girl had to use an ear insert for a total of 76 days following myringotomy because of repeated haemorrhage from the ear. the subsequent investigation using ct and angiography revealed ...20082614241
aberrant intratympanic internal carotid artery: a potentially hazardous anomaly.a case is presented of a 3-year-old girl with no previous history of ear disease or developmental defects who bled profusely upon (right) myringotomy. the haemorrhage could only be stopped with the aid of an ear insert and a nasopharyngeal balloon catheter. the balloon catheter was removed the following day but the girl had to use an ear insert for a total of 76 days following myringotomy because of repeated haemorrhage from the ear. the subsequent investigation using ct and angiography revealed ...20082614241
serum igg level against streptococcus mutans in subjects with caries experience.serum igg level against streptococcus mutans serotype c was studied in 33 subjects, in relation to dental caries, oral hygiene and age. the activity of the serum igg against the sonicated antigens of the bacterium was evaluated by micro-elisa. the serum igg titer to s. mutans was significantly higher in the subjects with no detectable carious lesions than in the subjects with active caries (p less than 0.05). however, there was no clear difference between the serum igg antibody to s. mutans and ...19892632131
serum igg level against streptococcus mutans in subjects with caries experience.serum igg level against streptococcus mutans serotype c was studied in 33 subjects, in relation to dental caries, oral hygiene and age. the activity of the serum igg against the sonicated antigens of the bacterium was evaluated by micro-elisa. the serum igg titer to s. mutans was significantly higher in the subjects with no detectable carious lesions than in the subjects with active caries (p less than 0.05). however, there was no clear difference between the serum igg antibody to s. mutans and ...19892632131
[surgical excision of the cancer of the stomach after 75 years of age].a retrospective study of 302 patients hospitalized for gastric adenocarcinoma in the period between 1976 and 1987 revealed that 133 of the patients (44%) were over 75 years of age. in order to bring out the characteristics of stomach cancer in the elderly, these patients were compared with younger subjects, as a comparison with a population of under seventies emphasizes the existing differences. clinical signs, the time necessary for reaching diagnosis, as well as the evolutive stage of the path ...20082632156
[surgical excision of the cancer of the stomach after 75 years of age].a retrospective study of 302 patients hospitalized for gastric adenocarcinoma in the period between 1976 and 1987 revealed that 133 of the patients (44%) were over 75 years of age. in order to bring out the characteristics of stomach cancer in the elderly, these patients were compared with younger subjects, as a comparison with a population of under seventies emphasizes the existing differences. clinical signs, the time necessary for reaching diagnosis, as well as the evolutive stage of the path ...20082632156
[participation of the olfactory system in the regulation of food intake].evoked potentials in the olfactory bulb (ob), lateral hypothalamus (hl) and rostral portion of the nucleus of the tractus solitarius (nts), were recorded after cervical vagus nerve stimulation. the slow component in the ob only was recorded in the periglomerular layer. electrolytic lesion of the nts, abolished the evoked potentials in the ob by vagus nerve stimulation. the results of the present experiments indicate that the pathway from the vagus nerve to ob go into the nts but probably not int ...19892633947
nuclear overhauser effects and conformations of branched trisaccharide methyl beta-glycosides that contain a 2,3-disubstituted galactose residue.on the basis of the n.o.e. data and theoretical calculations, it was found that less than 90% of one conformer was present in aqueous solution for each of a series of trisaccharide methyl beta-glycosides with a 2,3-disubstituted galactose residue.20082636043
when to do a lumbar puncture in a neonate. 20082650636
the birth of immunology. ii. metchnikoff and his critics.the presentation of the phagocytic theory of immunity, proposed by metchnikoff in 1883, was immediately attacked by german pathologists and microbiologists. led by baumgarten and ziegler, criticism was levied against the hypothesis in three general respects: 1) can an analogy truly be established between leukocyte phagocytosis and feeding of monocellular organisms? 2) what is compelling about the phagocytic process as a universal defensive activity? 3) general philosophic objections were raised, ...20092661021
[antioxidants in clinical practice]. 20092662464
exploration of cervico-encephalic vessels using trans-brachial approach on outpatients.among the several methods used for the exploration of supra-aortic vessels, none is perfect. the intra-arterial digital subtraction angiography is a secure method. the transbrachial approach for this purpose is a safe and efficient technique. the possible risks at the level of humeral artery can be reduced by applying the method described in the text. we present our experience among 200 patients, using mostly the right brachial artery. the quality of image was good in 3/4 of cases. humeral arter ...20092662882
mild hypertension: critical analysis of different therapeutic approaches.in 1988 the fourth joint national committee (jnc iv) issued new guidelines for the detection, evaluation, and treatment of hypertension. pharmacologic along with nonpharmacologic therapy is indicated for hypertensive patients whose diastolic blood pressures average greater than or equal to 95 mmhg over a period of time and for patients who have a diastolic blood pressure of 90 mmhg to 94 mmhg with evidence of target organ disease and/or other major risk factors. in the absence of target organ di ...20092663223
idiopathic unilateral hyperlucent lung.the entity of unilateral hyperlucent lung in the adult is presented as a disease which has its origins in childhood and carries the potential for cardiopulmonary morbidity.20092666886
dipstick urinalysis screening of asymptomatic adults for urinary tract disorders. ii. bacteriuria.using criteria adopted by the us preventive services task force, we evaluated use of the dipstick urinalysis to screen for bacteriuria. when the leukocyte esterase and nitrite dipstick tests are combined, the positive predictive value for detecting bacteriuria exceeded 12% in groups with a 5% or higher prevalence of bacteriuria: women who are pregnant, diabetic, or over 60 years of age and all institutionalized elderly. conventional antimicrobial regimens for asymptomatic bacteriuria have proved ...20062668583
dipstick urinalysis screening of asymptomatic adults for urinary tract disorders. ii. bacteriuria.using criteria adopted by the us preventive services task force, we evaluated use of the dipstick urinalysis to screen for bacteriuria. when the leukocyte esterase and nitrite dipstick tests are combined, the positive predictive value for detecting bacteriuria exceeded 12% in groups with a 5% or higher prevalence of bacteriuria: women who are pregnant, diabetic, or over 60 years of age and all institutionalized elderly. conventional antimicrobial regimens for asymptomatic bacteriuria have proved ...20062668583
impaired in-vitro proliferation of hemopoietic precursors in hiv-1-infected subjects.patients with acquired immunodeficiency syndrome (aids) and persistent lymphadenopathy syndrome (las) display significant hematological abnormalities of one or more cell lineages. in order to understand the pathophysiologic mechanisms leading to these abnormalities we studied the proliferation capacity of pluripotent and committed hemopoietic precursors using in-vitro colony assays. anemia, leukopenia and thrombopenia were relatively frequent findings in hiv-infected subjects irrespectively of t ...19892668646
impaired in-vitro proliferation of hemopoietic precursors in hiv-1-infected subjects.patients with acquired immunodeficiency syndrome (aids) and persistent lymphadenopathy syndrome (las) display significant hematological abnormalities of one or more cell lineages. in order to understand the pathophysiologic mechanisms leading to these abnormalities we studied the proliferation capacity of pluripotent and committed hemopoietic precursors using in-vitro colony assays. anemia, leukopenia and thrombopenia were relatively frequent findings in hiv-infected subjects irrespectively of t ...19892668646
making transgenic mice: is it really that easy? 20092669126
the sleep-promoting behaviors of habitual short- and longer-sleeping adults.consistent with the view that habitual longer-sleepers are more concerned with their sleep, this group (n = 25) reported engaging in twice as many sleep-promoting behaviors as a group of short-sleepers (n = 25). the longer sleepers tended to use alcohol and the short sleepers food to promote sleep.20092674882
penile pain and direct inguinal hernia. 20092676057
isolation of a high frequency donor of rhodobacter capsulatus by integration of the plasmid pmt1000 into the chromosome.the temperature-independent clone of rhodobacter capsulatus ua7041, carrying the temperature-sensitive plasmid pmt1000, has been obtained by selection for plasmid markers at the non-permissive temperature. the transfer to escherichia coli of all drug resistance encoded by pmt1000 was of about 10(-7) when the donor was the ua7041 strain, and of 5 x 10(-4) when the donor was the temperature-sensitive strain of r. capsulatus. electrophoretic analyses showed no plasmid band typical of the autonomous ...19892679770
[diagnostic proceedings in obstipation]. 20092684587
mast cell secretagogues. 20092685827
protein phosphorylation controls translation rates. 20092687263
insulin response and glucose tolerance in survivors of myocardial infarction.insulin response and glucose tolerance was studied in 25 adult patients who had survived acute myocardial infarction 2-24 months prior to study. the results were compared with 15 age and sex matched healthy controls. mean fasting glucose and serum insulin levels were normal in both groups. these values were significantly higher in patient group during glucose tolerance test (gtt) done after 75 g of glucose load. eight patients (32%) had abnormal glucose tolerance and hyperinsulinaemia. another 6 ...20092693435
membrane effects of the polyene antibiotic amphotericin b and of some of its derivatives on lymphocytes.amphotericin b (amb) exhibits immunomodulating properties in mice. in vitro studies on lymphocytes, in relation with these properties, are reported here with amb and two of its derivatives: the n-fructosyl (n-fru amb) and the n-thiopropionyl (ambsh) derivatives. interactions of these molecules with thymocytes, a sensitive cell type, demonstrated that the extent of binding is not a toxicity parameter. in contrast, membrane fluidity changes have been observed and appeared to be related to toxicity ...20092695832
[synthetic cephalosporins. v. synthesis and antibacterial activity of 3-alkylthio-7 beta-[(z)-2-(2-aminothiazol-4-yl)-2-(o-substituted oxyimino)acetamido]cephalosporins and related compounds].3-alkylthio-7 beta-[(z)-2-(2-aminothiazol-4-yl)-2-(o-substituted oxyimino)acetamido]cephalosporins (6 and 7) and the 3-methoxy analogues (10) were prepared by coupling diphenylmethyl 7-amino-3-alkylthio-3-cephem-4-carboxylate (1 and 2) or diphenylmethyl 7-amino-3-methoxy-3-cephem-4-carboxylate with (z)-2-(2-tritylaminothiazol-4-yl)-2-(o-substituted oxyimino)acetic acid (4), followed by deprotection and subjected to examination of antibacterial activities. the pivaloyloxymethyl esters (8 and 9) o ...19892698417
the international society for cardiovascular surgery (north american chapter), 36th scientific meeting. chicago, illinois (u.s.a.), june 13 and 14, 1988. abstracts. 20092708446
effect of a hypertonic lactated ringer's solution on intracranial pressure and cerebral water content in a model of traumatic brain injury.there has recently been an increased interest in the use of hypertonic solutions for fluid resuscitation of trauma victims. in this study, we examined the acute cerebral effects of a hypertonic lactated ringer's solution (measured osmolality = 469 mosm/kg) in an animal model of traumatic brain injury. following the production of a cerebral cryogenic lesion, eight new zealand white rabbits were randomized to undergo hemodilution with either lactated ringer's (measured osmolality = 254 mosm/kg) or ...19892709456
relationship of serum ferritin and iron concentrations and serum total iron-binding capacity to nonheme iron stores in dogs.the relationships of various iron-related analytes were evaluated in 95 dogs. liver and spleen nonheme iron content was determined coulometrically on acid-digested tissue specimens. serum iron concentration and total iron-binding capacity also were measured coulometrically, whereas serum ferritin concentration was measured by elisa. significant (p less than 0.0002) correlation was found between serum ferritin concentration and nonheme iron stores. significant correlation was not found between no ...19892719382
insensitivity, limited joint mobility, and plantar ulcers in patients with diabetes mellitus.the purpose of this study was to determine whether differences in sensation, ankle dorsiflexion (df), and subtalar joint (stj) motion exist between 1) diabetic patients with a history of plantar ulcer (dmw group), 2) diabetic patients without a history of plantar ulcer (dmwo group), and 3) a nondiabetic control group (ndc group). there were 23, 23, and 24 subjects in the respective groups. the mean age for each group was 58, 63, and 60 years, respectively. the mean df for each group was 2, 5, an ...20092727069
[aortobronchial fistula developing in a pseudoaneurysm of the horizontal aorta].amongst the rare causes of haemoptysis rupture of the great vessels is always a possibility. an aorto-bronchial fistula is a rare complication of thoracic aneurysms of the aorta. a fistula starting from a false aneurysm is exceptionally rare. our observation concerns a patient of 61 with previous vascular problems who was discovered to have a mediastinal tumour following dysphonia and haemoptysis. aortography and surgical intervention revealed that this was a false aneurysm of the horizontal par ...20092727372
psychology and violence against women.the discipline of psychology has made many contributions to the understanding of the social problem of men's violence against women during the past 15 years by reframing the problem as one of misuse of power by men who have been socialized into believing they are entitled to control the women in their lives, even by violent means. the new scientific psychology data base formed by integrating feminist gender analysis methods into more traditional psychological methodology is discussed, as are the ...20092729743
altman tapped to be new hcfa administrator. 19892731914
afferent renal nerve effects on plasma vasopressin and oxytocin in conscious rats.experiments were done in conscious, unrestrained, baroreceptor-intact rats to investigate the effects of afferent renal nerve (arn) stimulation on circulating levels of arginine vasopressin (avp) and oxytocin (oxy). electrical stimulation of arn elicited a rise in arterial pressure (ap) of 12 +/- 2 mmhg and no significant change in heart rate (hr). plasma concentrations of avp and oxy measured by radioimmunoassay were significantly increased immediately after the stimulation period. avp increase ...19892735450
intraerythrocytic ca2+ and mg2+ concentrations of theileria sergenti infected calves. 19892739229
"empty sella" with invasive microprolactinoma.we describe the unique association of an aggressive prolactin secreting pituitary microadenoma invading through the sphenoid sinus with an empty sella, in which the pituitary tumor remained clinically undiagnosed. the postmortem anatomy of this empty sella syndrome is presented. it is concluded that the phrase "empty sella", although universally accepted, correlates poorly with the underlying disease, and that terms such as "intrasellar arachnoidocele" or "intrasellar subarachnoid herniation" wo ...20092743648
occupational physicians in uk--numbers, training requirements and qualifications. 20092749054
heller's myotomy. 20092758279
botulinum toxin injection into the superior rectus muscle of the non-dominant eye for dissociated vertical deviation.a variety of surgical procedures on the superior rectus muscles have been proposed as a remedy for dissociated vertical deviation (dvd); botulinum toxin (oculinum) has been one such suggestion as a surgical alternative. we selected five older patients with dvd whose age placed them beyond a risk of amblyopia to evaluate oculinum injection into the superior rectus muscle as therapy for dvd. the patients achieved a reduction from the mean value of 20 prism diopters to the mean value of less than 5 ...20092760787
two- and three-dimensional ultrastructure of endothelium and pericyte interdigitations in capillary of human granulation tissue.two- and three-dimensional electron microscopic observation in the immature capillary of the human granulation tissue revealed cytoplasmic interdigitations (cid) between the endothelium and the pericyte. these were composed of a cytoplasmic projection and indentation, and there was a gap space without basement membrane-like components between the two cell membranes. plasmalemmal vesicles were frequently found locating beneath and/or attached to the cell membranes at the indentated side of the in ...19892769144
decreased 3 alpha-androstanediol glucuronide levels in plasma and random urines in male pseudohermaphroditism caused by 5 alpha-reductase deficiency.concentrations of 3 alpha-diol glucuronide (3 alpha-diol g) in plasma and/or random urine samples were determined in seven subjects with familial male pseudohermaphroditism (fmp) due to 5 alpha-reductase deficiency (5 alpha-rd). all subjects were natives of an isolated turkish village with a high incidence of consanguineous marriage. a specific and sensitive antibody to 3 alpha-diol was used for radioimmunoassay of 3 alpha-diol g after hydrolysis and chromatographic purification. the mean plasma ...19892770532
primary aortic sarcoma mimicking aortic dissection. 20092773804
reproducibility of treadmill exercise data in patients with atrial fibrillation.serial submaximal treadmill tests are often used to evaluate the efficacy of therapy in patients with atrial fibrillation. since the response to serial tests can be influenced by a 'learning phenomenon', we performed maximal exercise tests on 9 patients (mean age 63 +/- 4 years) with chronic atrial fibrillation. points of analysis for the initial and follow-up treadmill exercise tests were 3 mph/0% grade, the gas exchange anaerobic threshold, and maximal exertion. significant (p less than 0.05) ...20092776144
treatment of frey's syndrome (gustatory sweating) with topical glycopyrrolate: case report. 20072779907
coping with political violence in northern ireland.recent community based research, employing a self-assessed measure of psychological distress, has suggested that people in northern ireland may be coping relatively well with the stress of continuing political violence. this paper reports a first direct investigation of coping in northern ireland. using two scales from the folkman and lazarus ways of coping questionnaire--distancing and seeking social support--an attempt was made to investigate the role of coping in relation to local levels of v ...20082784590
post-irradiation regeneration of early b-lymphocyte precursor cells in mouse bone marrow.to examine the sequential development of early b-cell precursors in mouse bone marrow, b-lineage cells have been examined during a wave of post-irradiation regeneration. cell phenotypes have been defined using double-immunofluorescence labelling techniques for (i) terminal deoxynucleotidyl transferase (tdt); (ii) b220 glycoprotein, detected by the binding of mab 14.8; (iii); mu heavy chains in the cytoplasm (c mu) and at the cell surface (s mu). three populations of mu- cells (tdt+14.8-; tdt+14. ...19892784779
signet ring cell lymphoma of t cell type.a rare variant of non-hodgkin's lymphoma, signet ring lymphoma of t cell phenotype (only the fourth to be reported) in a 75 year old man was studied by light microscopy, immunohistochemistry, electron microscopy and gene rearrangement studies. ultrastructurally, a wider spectrum of cell size and nuclear shape was observed in this case than in the previously recorded cases. the morphology of the signet ring vacuoles was identical to that found in the commoner b cell signet ring lymphoma of clear ...19892784803
[spontaneous interleukin 1 secretion by alveolar macrophages from the bronchoalveolar lavage of patients with active sarcoidosis].alveolar macrophages from 28 patients with pulmonary sarcoidosis, from 6 patients with idiopathic pulmonary fibrosis and from 8 control subjects were tested for their spontaneous interleukin-1 release. whereas alveolar macrophages from the controls and from the patients with idiopathic pulmonary fibrosis did not show a significant release of interleukin 1, 14 of the sarcoidosis patients displayed a considerable spontaneous interleukin-1 secretion. besides radiographic signs of an increased disea ...19892789181
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