Publications

[incidence of autopsies in france. consequence on the estimation of sudden death rate according to regions. results from an epidemiologic survey on postneonatal mortality].	in order to assess the actual rate of sudden infant death in france, an epidemiological survey was carried out. all the deaths of the postneonatal period were investigated from september 1986 to december 1987. the parents of the babies and the certifying physicians were involved in the survey, the results of the post mortem investigations were recorded. that material showed a low rate of necropsies among the sudden infant deaths (31% at the national level) and wide variations in the rates betwee ...	2006	1610274
information technology: implementing a nurse information system.	this article explains the remit of a specially designated project nurse in preparing for the implementation of a nurse information system. the main components of a system--rostering/staff planning, workload/dependency levels and care planning--are defined and the project nurse's role in educating ward-based staff is described. the key to successful management of the necessary changes, the author argues, is adopting a 'bottom-up' approach to implementation in which nurses are encouraged to develo ...	2006	1622800
[eye foreign bodies. patients should be sent to the eye clinic for treatment].		2006	1636298
minority student nurses' perceptions of their educational program.		2006	1773054
continuous spinal anesthesia with hyperbaric and isobaric bupivacaine.		2006	1796979
continuous spinal anesthesia with hyperbaric and isobaric bupivacaine.		2006	1796979
topical cyclosporine in vernal keratoconjunctivitis.	in a placebo-controlled, double-masked clinical trial, the authors evaluated the effects of topical 2% cyclosporine on 20 patients with vernal keratoconjunctivitis (vkc). nineteen patients were male and one was female. patients ranged in age from 5 to 19 years (mean, 9.7 years). symptoms of itching, tearing, photophobia, discharge, and foreign body sensation were evaluated and recorded at weekly intervals for a period of 6 weeks. there was a statistically significant decrease in the conjunctival ...	2007	1800929
a variant of nephrogenic diabetes insipidus: v2 receptor abnormality restricted to the kidney.	in congenital nephrogenic diabetes insipidus (ndi) blunted responses of plasma factor viii, von willebrand factor, and plasminogen activator to the synthetic v2 analogue 1-desamino-8-d-arginine vasopressin (ddavp) have been reported. in addition, vasodilatory responses to ddavp appear to be absent in ndi. we describe a boy, who presented shortly after birth with the typical features of ndi, but who showed normal coagulation, fibrinolytic and vasodilatory responses to ddavp. we conclude that in t ...	2006	1828422
a variant of nephrogenic diabetes insipidus: v2 receptor abnormality restricted to the kidney.	in congenital nephrogenic diabetes insipidus (ndi) blunted responses of plasma factor viii, von willebrand factor, and plasminogen activator to the synthetic v2 analogue 1-desamino-8-d-arginine vasopressin (ddavp) have been reported. in addition, vasodilatory responses to ddavp appear to be absent in ndi. we describe a boy, who presented shortly after birth with the typical features of ndi, but who showed normal coagulation, fibrinolytic and vasodilatory responses to ddavp. we conclude that in t ...	2006	1828422
regulation of alcohol consumption by the renin-angiotensin system: a review of recent findings and a possible mechanism of action.	the renin-angiotensin system has traditionally been associated with the regulation of fluid and electrolyte balance. in this review we summarize the data which ascribes a completely new function to this system, i.e., the regulation of alcohol consumption. in addition, we suggest a possible mechanism for this effect based on the concept of a satiety or stop process. the approach taken was to examine the effect on alcohol intake of a wide variety of drug, genetic, dietary, surgical and neurosurgic ...	2007	1852316
olfactory dysfunction in parkinson's disease.	an olfactory function test in 18 patients with parkinson's disease (pd) and 10 age-matched control subjects was performed. both detection and recognition thresholds were measured with five kinds of synthesized odorants (t & t olfactometry). before each test, rhinoscopic inspections were performed to exclude subjects who could have respiratory hyposmia. both detection and recognition thresholds in patients with pd were significantly elevated in comparison with those of control subjects. auditory ...	2007	1852411
horn fly (diptera: muscidae) insecticide resistance in kentucky and arkansas.	the effect of previous insecticide use patterns for horn fly control on the susceptibility spectrum of horn fly (haematobia irritans [l.]) populations from kentucky and arkansas is described. populations of horn flies from both states were tested with three pyrethroids (cyhalothrin, cypermethrin, and permethrin), three organophosphates (diazinon, pirimiphos methyl, and tetrachlorvinphos), and a chlorinated hydrocarbon (methoxychlor). dose-mortality data indicated insecticide resistance in arkans ...	1991	1885841
diabetes-induced rat hyposensitivity to compound 48/80.	rat mortality and contractile responses of isolated tracheas to compound 48/80 from rats made diabetic 4 days before by a single intravenous injection of alloxan and from diabetic rats that had been treated with insulin 6 h before were compared with control animals. diabetic animals and tracheal segments from diabetic rats were significantly less responsive to compound 48/80 than control and insulin-treated diabetic animals. on the other hand, diabetic animals have a lower quantity of peritoneal ...	1991	1913334
an ultrastructural study of in vivo interactions between lymphocytes and endothelial cells in the pathogenesis of the vascular leak syndrome induced by interleukin-2.	lymphokine-activated killer (lak) cells play a major role in the induction of the vascular leak syndrome (vls). to understand the mechanism of this syndrome, the authors examined light and electron microscopic alterations in the lung, liver, spleen, kidney, and heart of mice in which vls was produced by the administration of interleukin-2 (il-2) (seven injections of 600,000 iu each for a period of 4 days). the results of these studies disclosed that considerable damage had been done to the endot ...	2007	1913455
getting the message across.		2006	1945130
[postcoital uterine microbe colonization and endometritis in the mare].	in the mare, natural breeding is associated with bacterial contamination of the reproductive tract. the purpose of this study was to examine postcoital bacterial contamination and the resulting inflammatory response of the uterus. uterine swabs for bacteriological and cytological examination were obtained from 80 mares. each mare was sampled once between 4 and 69 hours postbreeding. in mares which did not conceive, sampling was repeated at the following estrus. the findings were compared with th ...	1991	1948985
seventh international meeting of the society for advancement of contraception. singapore, 4-11 november 1990.		2007	1950709
job-related stress: perceptions of employee pharmacists.		2007	1951038
a 5-year follow-up study of 117 battered women.	this paper reports register data concerning somatic and psychiatric hospital care on 117 battered women who were identified in a surgical emergency department and offered a treatment program. data were collected during a period of 10 years before to 5 years after the battering in question. it was concluded that the battered woman seeks hospital care much more than the average woman of the same age. it is, however, not only traumatic injuries that bring her to the hospital, but also medical, gyne ...	2007	1951810
lymph node staging in patients with clinically negative neck examinations by ultrasound and ultrasound-guided aspiration cytology.	to assess the usefulness of ultrasound and ultrasound-guided fine-needle aspiration cytology in detecting occult cervical lymph node metastases, 107 patients with squamous cell carcinoma of the head and neck, who underwent 132 elective neck dissections, had preoperative ultrasound examination. during the assessment of the last 54 patients, who underwent 70 elective neck dissections, ultrasound-guided aspiration cytology was available. although ultrasound was able to detect lymph node metastases ...	2007	1951890
[principle of dental public health in aging society].		2007	1951936
osteoporosis associated with rheumatoid arthritis: pathogenesis and management.	rheumatoid arthritis is associated with both localized and generalized osteoporosis. localized osteoporosis can be considered to be caused by local disease mechanisms, including the generation of factors from activation of the cytokine pathway. the etiology of generalized osteoporosis has been difficult to elucidate, particularly because of the lack of sensitive techniques to measure bone mineral density. the introduction of single- and dual-photon absorptiometry and quantitative computed tomogr ...	2007	2042057
ifosfamide, doxorubicin and etoposide in small cell lung cancer patients with poor prognosis.	61 patients with small cell lung cancer in a poor prognosis group were treated with chemotherapy and with thoracic radiotherapy if they had 'limited stage' disease. no prophylactic cranial irradiation was given. chemotherapy comprised doxorubicin 50 mg/m2 and ifosfamide 5 g/m2 with mesna on day 1, and etoposide 120 mg/m2 intravenously on days 1 and 2 and 240 mg/m2 orally on day 3. treatment was repeated every 3 weeks for a maximum of six courses and no dosage reductions were allowed. complete re ...	2007	2168191
protective effect of inactivated pasteurella haemolytica bacterin challenged in bovine herpesvirus-1 experimentally infected calves.	formalin-inactivated and sonicated pasteurella haemolytica bacterins were prepared from 1 h cultures of bacterial pellets in rpmi-1640 medium containing 7% fetal calf serum. the bacterial pellets were obtained from logarithmic phase growth of the organism by centrifugation. the protective effect of the vaccine was evaluated in 43 specific-pathogen-free hereford crossbred calves and yearlings in three experiments. cattle were either single vaccinated or boosted via three routes; intratracheally ( ...	1990	2168606
phosphonylmethyl ethers of acyclic nucleoside analogues: inhibitors of hsv-1 induced ribonucleotide reductase.	diphosphates of n-(s)-(3-hydroxy-2-phosphonylmethoxypropyl) and n-(2-phosphonylmethoxyethyl) derivatives of purine and pyrimidine heterocyclic bases inhibit hsv-1 encoded ribonucleotide reductase. of the compounds studied, the most efficient inhibitors of cdp reduction (at 5.1 mumols.l-1) by the hsv-1-encoded enzyme are hpmpapp (ic50 = 0.9 mumols.l-1) and pmeapp (ic50 = 8 mumol.l-1). pmeapp does not inhibit the enzyme isolated from the mutant hsv-1 kos strain pmear which is resistant to pmea at ...	1990	2168691
nitrate reductases of escherichia coli: sequence of the second nitrate reductase and comparison with that encoded by the narghji operon.	the structural genes for nrz, the second nitrate reductase of escherichia coli, have been sequenced. they are organized in a transcription unit, narzywv, encoding four subunits, narz, nary, narw and narv. the transcription unit is homologous (73% identity) to the narghji operon which encodes the genes for nra, the better characterized nitrate reductase of this organism. the level of homology between the corresponding polypeptides ranges from 69% for the narw/narj pair to 86% for the narv/nari pa ...	1990	2233673
[unwanted pregnancy after removal of the iud].	four cases of unwanted pregnancy occurring in the same cycle as removal of an iud are presented. the duration of ovum transport from the fallopian tube into the uterine cavity, survival of spermatozoa in the female genital tract and timing of ovulation, which may be delayed in women with iuds are variables which influence the probability of pregnancy and should be taken into consideration when removing an iud. unless pregnancy is desired, it is recommended when possible not to remove an iud afte ...	2007	2238201
[unwanted pregnancy after removal of the iud].	four cases of unwanted pregnancy occurring in the same cycle as removal of an iud are presented. the duration of ovum transport from the fallopian tube into the uterine cavity, survival of spermatozoa in the female genital tract and timing of ovulation, which may be delayed in women with iuds are variables which influence the probability of pregnancy and should be taken into consideration when removing an iud. unless pregnancy is desired, it is recommended when possible not to remove an iud afte ...	2007	2238201
[effect of enalapril on heart rate, arterial blood pressure and exocrine pancreatic secretion in the alert dog].	a changed exocrine pancreatic secretion could be a pathogenetic factor of an acute pancreatitis after administration of angiotensin-converting enzyme (ace) inhibitors. in six conscious dogs with gastric and duodenal thomas fistulas we studied the effect of an intravenous (iv.) bolus injection of 10 mg enalaprilat, an intraduodenal (id.) bolus injection of 20 and 40 mg enalapril (e.), and 0.15 m nacl (20 ml iv., resp., id.) on pancreatic bicarbonate- and protein output in response to secretin (20 ...	1990	2238764
[current trends in the therapy of respiratory tract infections].		2008	2266917
[current status of national indemnity and bilateral hilar adenopathy in siberian silicosis].		2008	2277423
[quantitative characteristics of microcirculation bed in aseptic inflammation of the rat uterus and with the background of the use of carbon-mineral sorbents].	we studied the volume compactness of the arterial, capillary and venous parts of the microcirculation channel after 24, 48, 72 and 96 hours of the aseptic inflammation and after local application of the carbon-mineral sorbents in the rat's uterus. the local sorption decreased the reaction of the inflammation in the endo- and myometrium.	1990	2279103
estimation of time by patients with positive and negative schizophrenia.	in a prior study, schizophrenic patients' tendency to over-estimate short time intervals was about the same for the different types of schizophrenia (dsm-iii criteria). reanalysis showed patients with positive and negative schizophrenia did not differ in their time estimations.	2008	2293184
neurological examination in subjects over 65 years: an epidemiological survey.	the frequency of abnormal findings at neurological examination was analyzed in an unselected sample of elderly people aged 67-87 years. absent deep tendon reflexes and impairment of proprioceptive sensation rarely occurred in the elderly. limitation of upward gaze and convergence appear a common finding, especially in the very old. overall, the presence of cortical disinhibition signs (primitive reflexes and paratonia) did not discriminate well between subjects without cns disease and demented p ...	2008	2330069
health care in the united states. our dynamic jigsaw puzzle.		2008	2405797
[an original flap: the arterialized venous flap].		2008	2435207
[intermittent peritoneal chronic dialysis in diabetic patients: effect of the technique on blood glucose and protein loss during the procedure].	we performed a prospective study in 4 diabetic (one insulin dependent) patients with end stage chronic renal disease, in whom intermittent peritoneal dialysis was performed with and without addition of insulin to the dialysate. plasma levels of glucose and insulin were compared to those obtained in 5 non-diabetic controls. with no insulin added, absolute changes in glucose and insulin from predialysis levels were similar in diabetics and non-diabetics. the addition of insulin to the dialysate di ...	2008	2519375
effects of human pth-related peptide and human pth on cyclic amp production and cytosolic free calcium in an osteoblastic cell clone.	recently, human parathyroid hormone-related peptide (hpthrp) has been purified and its amino acid sequence determined. within the amino-terminal 13 residues of hpthrp, 8 amino acids were found homologous between hpthrp and human pth (hpth). this peptide was reported to stimulate cyclic amp (camp) production in osteoblastic cell lines (umr106 and ros17/2.8). however, whether or not this peptide affects another second messenger, i.e., cytosolic free calcium ([ca2+]i), in osteoblasts has not yet be ...	1989	2546638
characterization of the rela1 mutation and a comparison of rela1 with new rela null alleles in escherichia coli.	the most widely studied "relaxed" mutant of the rela locus, the rela1 allele, is shown here to consist of an is2 insertion between the 85th and 86th codons of the otherwise wild-type rela structural gene, which normally encodes a 743-amino acid (84 kda) protein. the rela protein is a ribosome-dependent atp:gtp (gdp) pyrophosphoryltransferase that is activated during the stringent response to amino acid starvation and thereby occasions the accumulation of guanosine 3',5'-bispyrophosphate (ppgpp). ...	1989	2556396
effect of psoralens and ultraviolet radiation on murine dendritic epidermal cells.	monofunctional psoralens produce less phototoxicity than bifunctional psoralens after ultraviolet a (uva) irradiation. we investigated the effect of repetitive treatments with angelicin (isopsoralen), a monofunctional psoralen, plus uva radiation (ipuva) on the number and morphology of dendritic epidermal cells (dec). this effect was compared with that of 8-methoxypsoralen plus uva radiation (puva), uva alone, and uvb radiation. c3h/hen mice were treated topically with the drugs three times/wk f ...	2008	2565931
attenuation of defensive threat and attack in wild rats (rattus rattus) by benzodiazepines.	a battery of tests designed to elicit reactions to a variety of non-painful threat stimuli was used to study the effects of chlordiazepoxide (5-20 mg/kg), diazepam (1-5 mg/kg) and midazolam (1-10 mg/kg) on the defensive repertoire of wild rattus rattus. the most consistent effect of benzodiazepine treatment, across compounds and tests, was a marked reduction in defensive threat and attack behaviors, with midazolam effective over a wider range of situations. in contrast, effects on freezing and f ...	1989	2566187
[amino acid reserves of the blood in patients with schizophrenia and their correction in insulin coma].	free amino acid content was measured in the blood serum in patients with permanently progressive paranoid schizophrenia under conventional insulin shock therapy. the influence of several amino acids (methionine, glutamic acid) preinjection on their base levels was also assessed. metabolic response to the insulin coma was different in preinjected vs. control groups. glutamine acid-preinjected patients displayed less pronounced shifts in amino acid reserves in the blood serum that smoothed the sho ...	2008	2566218
partial coexistence of growth hormone-releasing hormone and tyrosine hydroxylase in paraventricular neurons in rats.	immunocytochemistry revealed growth hormone-releasing hormone (grf)-containing cells (4-10/50 microns thick coronal sections) in the ventral portion of the medial parvicellular subdivision of the paraventricular nucleus (pvn) in the rat. in the same region we also detected about the same number of neurons containing the mrna that encodes grf using in situ hybridization histochemistry. fluorescence double labelling immunohistochemistry showed the presence of grf and tyrosine hydroxylase (th) in t ...	1989	2573894
cytotoxicity and effect on mutagenicity of buffers in a microsuspension assay.	we have examined the effects of three buffers--vogel-bonner minimal e (vbm) and 0.15 and 0.015 m sodium phosphate, ph 7.4--and two concentrations of overnight cells (5x and 10x) on the mutagenicity of two pure compounds and two complex mixtures in strain ta98 using a modification of a microsuspension assay developed by kado et al. (mutation research 121:25-32, 1983). the assay was performed by adding 50 microliters of cell concentrate of an overnight culture of ta98 resuspended in the appropriat ...	1989	2575290
blood steroid levels in the goldfish: measurement of six ovarian steroids in small volumes of serum by reverse-phase high-performance liquid chromatography and radioimmunoassay.	a reliable and rapid technique for the measurement of estradiol-17 beta, testosterone, progesterone, 17 alpha-hydroxyprogesterone, 17 alpha,20 beta-dihydroxy-4-pregnen-3-one, and cortisol by reverse-phase high-performance liquid chromatography and radioimmunoassay in single female goldfish serum samples of 50 microliters was developed. the steroids were extracted with sep-pak c18 cartridges after heat treatment. while estradiol-17 beta was assayed directly after extraction, the other steroids we ...	2008	2583470
relation between all cause standardised mortality ratios and two indices of deprivation at regional and district level in england.	the use of mortality data in the form of standardised mortality ratios (smrs) to measure the need for health care resources in the resource allocation working party (rawp) formula in england has been criticised for underestimating the wider effects of adverse socioeconomic conditions on need, particularly in inner city areas. to assess this criticism, we explored the relationships at nhs regional and district levels in england between two indicators of illness from the 1981 census, two contrasti ...	2008	2592910
development of a statewide trauma registry.	in october 1986, the pennsylvania trauma systems foundation (ptsf) developed a statewide registry. development concentrated on four major issues: 1) data elements; 2) patient selection; 3) confidential mandatory involvement for trauma centers; and 4) reporting/analysis. the overall compliance of the trauma centers was 81.5%. documentation of prehospital run times and admission trauma scores were 21% and 70%, respectively. ptsf patients 55 years or older (27.9%) had twice the mortality as younger ...	2008	2593198
[clinical study of osteoporosis].		2008	2614196
scabies mimicking bullous pemphigoid.		2009	2643638
prenatal sonographic diagnosis of congenital sacrococcygeal teratoma and management.	teratomas are tumors containing tissues derived from all three germinal cell layers. most teratomas arise in the sacrococcygeal region, with a reported incidence of 1/40,000 births. during labor, severe dystocia may occur in infants with large tumors if delivered vaginally, with an extremely high fetal morbidity and mortality rate. reported is a case of a large congenital sacrococcygeal teratoma diagnosed antepartum by sonography at 36 weeks pregnancy. this sonographic finding allowed us to avoi ...	2009	2681670
phosphoroselenoate oligodeoxynucleotides: synthesis, physico-chemical characterization, anti-sense inhibitory properties and anti-hiv activity.	oligodeoxynucleotides with a phosphorus atom in which one of the non-bridging oxygen atoms is substituted by selenium were prepared and investigated with respect to their antisense properties. a general synthesis of phosphoroselenoate analogs of oligonucleotides is described using potassium selenocyanate as the selenium donor. the compounds, characterized by 31p nmr, were shown to decompose to phosphate with a half-life of ca. 30 days. melting temperatures of duplexes between poly(ra) or poly(ri ...	1989	2682524
transcardiac passage of thrombus--ultrasonographic visualization.	a patient is described in whom a right atrial thrombus was seen, by two-dimensional echocardiography, in the act of embolizing into the pulmonary circulation.	2009	2702500
fever and urticaria in acute giardiasis.	travelers' diarrhea afflicts some 250 million people yearly. a number of etiologic agents have been identified, including bacteria, viruses, and parasites. giardia lamblia is one of the pathogens clearly associated with this syndrome. typical symptoms of giardiasis that include abdominal bloating and cramps are well known, whereas urticaria has rarely been associated with this illness. an american tourist developed acute giardiasis accompanied by urticaria and high fever. no other pathogens were ...	1989	2705846
leptomeningeal gliomatosis with spinal cord or cauda equina compression: a complication of supratentorial gliomas in adults.	seven patients with supratentorial gliomas developed leptomeningeal gliomatosis (lmg) without symptomatic recurrence at the primary tumor site. in all, severe back and radicular pain, often simulating disc disease, preceded the development of spinal cord or cauda equina dysfunction. in 4 instances, intracranial hypertension due to hydrocephalus developed prior to spinal involvement. cytological examination of the csf revealed malignant cells in only 2/7 but a myelogram was diagnostic in all 7. a ...	2009	2711819
[fibrinogen, atherosclerosis, inflammation. satellite symposium. angio dyn 88. toulouse, 5 october 1988. proceedings].		2009	2715733
composition of very-low-density lipoproteins in non-insulin-dependent diabetes mellitus.	we studied the characteristics of very-low-density lipoproteins (vldls) composition in patients with non-insulin-dependent diabetes mellitus. vldls were isolated from 28 diabetics and 33 nondiabetics with a wide range of plasma lipid concentrations, so we could compare vldl composition between the two groups at similar lipid concentrations. the mean cholesterol and triglyceride concentrations in plasma of diabetic subjects were 2170 (sd 570) and 2510 (sd 2230) mg/l, respectively, and 2230 (sd 56 ...	2009	2720974
in vivo dna cross-linking by cyclophosphamide: comparison of human chronic lymphatic leukemia cells with mouse l1210 leukemia and normal bone marrow cells.	alkaline elution was done on a variety of cells following cyclophosphamide (cy) treatment in vivo. cells used were l1210 leukemia, normal mouse bone marrow, and peripheral blood cells obtained from a patient with chronic lymphatic leukemia (cll). endpoints used were determination of single strand breaks, dna-dna interstrand and dna-protein cross-links. after treatment of mice with cy (4 mg/mouse), low levels of single strand breaks were observed in both l1210 leukemia and cdf1 normal bone marrow ...	1989	2731167
effects of precocene analogs on the nematode caenorhabditis remanei (var. bangaloreiensis). ii. competitions with a juvenile hormone analog (methoprene).	fourteen 7-alkoxy-2,2-dimethychromenes were synthetized and studied in jh competition experiments: precocenes (ps) pi and pii, and synthetic analogs (pas) including (i) three with both antiallatal and p-like activities: 7-ethoxy-pii (7-epii); 7-(prop-2-ynyloxy)-2,-2-dimethylchromene (ppi); and 6-methoxy-7-(prop-2-ynyloxy)-2,2-dimethylchromene (ppiii); (ii) six without antiallatal activity, exerting p-like activity in nematodes; and (iii) three without either antiallatal or p-like activity, but w ...	2009	2737453
[we distance ourselves from a common basic education].		2009	2741005
a linear muscle model predicts the hyperbolic force-velocity relationship.	a variety of different schemes have been reported in the literature for linearizing the force-velocity relationship observed in muscle, a dominant element in the muscle. this report extends assertions that a linear muscle system has force-velocity characteristics as described by hill's hyperbolic equation, and that no linearization whatsoever is required. the muscle is modeled as a parallel combination of passive elasticity, and series elasticity connected to the parallel combination of active s ...	2007	2742961
accurate and efficient rna polymerase iii transcription in a cell-free extract prepared from ascaris suum embryos.	high-speed supernatant (s100) extracts derived from homogenized ascaris suum embryos efficiently transcribe added rna polymerase iii templates including cloned 5s rrna genes of the filarial parasite brugia malayi. several criteria, including two-dimensional rnase t1 oligonucleotide fingerprint analysis, indicate that in vitro transcription is accurately initiated and terminated.	1989	2747746
gradient recalled echo mr imaging of superior sagittal sinus occlusion.	with t1-weighted gradient recalled echo (gre) mr images and flow compensation, we studied the superior sagittal sinus in 3 normal volunteers and 3 patients with sinus occlusion. in these images, sites of patency of the superior sagittal sinus were identified due to the high signal intensity of the normal sinus. tumor invading the sinus was nearly isointense with cerebral gray matter. t1-weighted gre imaging proves to be an effective technique to evaluate sinus blood flow.	2009	2747889
the influence of endogenous and exogenous factors on the course and the results of experimental work with human tumor tissue on athymic nude rodents.		1989	2749469
twenty-year comparison of the human allograft and porcine xenograft.	this study compares a retrospective consecutive series of human allografts and concurrent porcine xenografts implanted over a 10-year interval. there were 571 allograft valves and 1,351 xenograft valves implanted in the aortic and mitral position with mean follow-up of 12.8 years for the allografts and 6.2 years for the xenografts. this study compares the incidence of structural deterioration over long-term follow-up. we found that there was no significant difference between four manufacturers o ...	1989	2774760
[single photon emission computed tomography by using n-isopropyl-p-[123i]-iodoamphetamine and 99mtc-hexamethyl propyleneamine oxime in a patient with herpes simplex encephalitis].	single photon emission computed tomographies (spects) by using n-isopropyl-p-[123i-imp]-iodo-amphetamine (123i-imp) and 99mtc-hexamethyl propyleneamine oxime (99mtc-hm-pao) were serially performed in a 70 yrs. old male with herpes simplex encephalitis (hse), and the chronological changes of accumulations were studied. accumulations of both 123i-imp and 99mtc-hm-pao increased initially, and then decreased with the stage of hse being advanced. the sequential appearance of the lesion in hse with 12 ...	2009	2786584
how to select a blood glucose meter for hospital use.		2009	2791853
role of antibiotic prophylaxis in retropubic surgery for stress urinary incontinence.	the effectiveness of prophylactic antibiotics was studied prospectively in 26 women undergoing retropubic urethropexy for genuine stress incontinence. each of the 14 patients in the antibiotic prophylaxis group received three 1-g doses of intravenous cefazolin administered before, during, and 6-8 hours after surgery. twelve women served as a control group and did not receive prophylactic antibiotics. postoperative febrile morbidity and hospital stay were significantly less (p less than .01 and p ...	2010	2797640
basal ganglia regional glucose metabolism asymmetry during a catatonic episode.		2009	2804192
basal ganglia regional glucose metabolism asymmetry during a catatonic episode.		2009	2804192
ontogeny of androgen receptors in fetal guinea pig brain.	sexual differentiation of the guinea pig brain is androgen dependent. to understand the cellular mechanisms of androgen action, we studied the ontogeny of cytosolic (arc) and nuclear (arn) androgen receptors in the brains and anterior pituitaries of fetal, neonatal, and adult guinea pigs. using cytosol from the hypothalamus-preoptic area-amygdala-septum of 60- to 65-day fetuses and nuclear preparations from 6-day-old neonates treated with testosterone propionate, validation studies revealed an a ...	1989	2804213
ontogeny of androgen receptors in fetal guinea pig brain.	sexual differentiation of the guinea pig brain is androgen dependent. to understand the cellular mechanisms of androgen action, we studied the ontogeny of cytosolic (arc) and nuclear (arn) androgen receptors in the brains and anterior pituitaries of fetal, neonatal, and adult guinea pigs. using cytosol from the hypothalamus-preoptic area-amygdala-septum of 60- to 65-day fetuses and nuclear preparations from 6-day-old neonates treated with testosterone propionate, validation studies revealed an a ...	1989	2804213
effect of evolution on the kinetic properties of enzymes.	1. the likely effect of a selective pressure in the direction of higher reaction fluxes on rate parameters for enzyme reactions confirming to michaelis-menten kinetics has been analyzed on the basis of relationships which take into account the changes in metabolite concentrations that must be associated with mutational changes of the kinetic properties of enzymes participating in metabolic pathways. 2. arguments are presented to show that such a pressure should tend to increase kcat, whereas km ...	2009	2806240
obstetrical medication and the human newborn: the influence of alphaprodine hydrochloride on visual behaviour.	the visual habituation of two groups of newborn infants was tested at a mean age of 2.9 days with large achromatic squares of varying luminance. mothers of the infants in one group received no medication during labour; mothers in the second group received a single dose of the synthetic narcotic alphaprodine hydrochloride. the two groups did not differ in the number of trials to reach the criterion, but newborns in the no-medication group fixated the stimuli for much longer periods than did infan ...	1989	2806744
formation of mboii vectors and cassettes using asymmetric mboii linkers.	class-iis restriction endonucleases such as mboii cleave dna at a specified distance away from their recognition sequences. this feature was exploited to cleave dna at previously inaccessible locations by preparing special asymmetric linker/adapters containing the mboii recognition sequence. these could be joined to dna fragments and subsequently cleaved by mboii. attachment of a 3' phosphate to one of the two different oligodeoxynucleotides comprising the asymmetric duplex prevented ligation at ...	1987	2820843
formation of mboii vectors and cassettes using asymmetric mboii linkers.	class-iis restriction endonucleases such as mboii cleave dna at a specified distance away from their recognition sequences. this feature was exploited to cleave dna at previously inaccessible locations by preparing special asymmetric linker/adapters containing the mboii recognition sequence. these could be joined to dna fragments and subsequently cleaved by mboii. attachment of a 3' phosphate to one of the two different oligodeoxynucleotides comprising the asymmetric duplex prevented ligation at ...	1987	2820843
regulatory functions of protein phosphorylation in meiotic maturation of mouse oocytes in vitro.		1988	2853366
regulatory functions of protein phosphorylation in meiotic maturation of mouse oocytes in vitro.		1988	2853366
a novel peptide vasoconstrictor, endothelin, is produced by vascular endothelium and modulates smooth muscle ca2+ channels.	since the discovery of endothelium-dependent vasodilation, vascular endothelium has been recognized as an important functional unit contributing to the regulation of vascular tonus. recent purification, structure determination and molecular cloning of a novel peptidergic vasoconstrictor, endothelin, from the culture supernatant of porcine aortic endothelial cells has further substantiated this concept. starting from a large quantity of serum-fee endothelial cell-conditioned medium, endothelin wa ...	1988	2853725
the restricted list of nhs drugs: a burning question.		2010	2857857
development of udp-glucuronosyltransferase activity toward digitoxigenin-monodigitoxoside in neonatal rats.	glucuronidation is low or undetectable in embryonic and early fetal tissues and changes to adult levels at rates depending on the acceptor, tissue, and species. because other data indicate there may be a specific udp-glucuronosyltransferase (gt) in the liver of adult rats that glucuronidates digitoxigenin-monodigitoxoside (dig), the development of gt activity in neonatal rats toward dig was compared with that of other acceptors. conjugation of p-nitrophenol and 1-naphthol was higher at birth and ...	1985	2859166
development of udp-glucuronosyltransferase activity toward digitoxigenin-monodigitoxoside in neonatal rats.	glucuronidation is low or undetectable in embryonic and early fetal tissues and changes to adult levels at rates depending on the acceptor, tissue, and species. because other data indicate there may be a specific udp-glucuronosyltransferase (gt) in the liver of adult rats that glucuronidates digitoxigenin-monodigitoxoside (dig), the development of gt activity in neonatal rats toward dig was compared with that of other acceptors. conjugation of p-nitrophenol and 1-naphthol was higher at birth and ...	1985	2859166
[criteria of the reactions of immature nerve tissues to oxygen deficiency and possibilities of its control].		1985	2863001
cell lineage and segmentation in the leech.	segments in the leech arise by the proliferation of longitudinally arrayed bandlets of blast cells derived from ten identifiable embryonic stem cells, two m, two n, four o/p and two q teloblasts. in each bandlet, older blast cells lie ahead of those born later. by using microinjected cell lineage tracers it was shown previously that the teloblasts give rise to characteristic cell patterns made up of segmentally iterated complements of progeny designated as m, n, o, p and q kinship groups. when a ...	2010	2869529
fatal temazepam overdoses.		2010	2873474
analgesic effectiveness of topically applied dynorphin on human dental pulp.		1986	2876436
[therapeutic aspects of infantile asthma. part i].		2010	2876486
the ascending projections of the dopaminergic neurons of the substantia nigra, zona reticulata: a combined retrograde tracer-immunohistochemical study.	the efferent projections of the dopaminergic neurons in the zona reticulata of the substantia nigra were examined using a combined retrograde tracer-immunohistochemical method. these dopamine (da) neurons were found to project exclusively to striatal targets in a topographically defined fashion. the zona reticulata da neurons do not innervate mesolimbic or mesocortical dopaminergic terminal fields, nor do they project to the superior colliculus or the ventromedial thalamic nucleus. these data su ...	1986	2879262
frequency of fimbriation of nontypable haemophilus influenzae and its ability to adhere to chinchilla and human respiratory epithelium.	to date, we have examined nearly 60 clinical isolates of nontypable haemophilus influenzae (26 nasopharyngeal, 33 from middle ear effusions) and have found that 100% were fimbriated. the percentage of cells bearing fimbriae within each isolate varied from less than 10 to 100%, with fimbriae being either peritrichous or bipolar in distribution. fimbriae were approximately 2.4 to 3.6 nm in width; however, there was a high degree of variability in both length and number of fimbriae per individual b ...	1988	2892792
comparison of adrenal medullary, carotid body and pc12 cell grafts in 6-ohda lesioned rats.	the survival and functional properties of dispersed cell implants of catecholaminergic cells obtained from the peripheral nervous system of adult rats (adrenal medulla and carotid body glomus cells) and pc12 cells from a rat pheochromocytoma cell line were examined following transplantation into the striatum of the adult rat. the host animals, all with unilateral 6-hydroxydopamine (6-ohda) nigrostriatal lesions, were divided into 5 groups: (1) pc12 cells transplanted into cyclosporin-a treated h ...	1988	2896533
a controlled trial of esmolol for the induction of deliberate hypotension.	twenty-five patients scheduled for lumbar fusion or cerebrovascular surgery were enrolled in an open label treatment controlled study comparing blood pressure and heart rate responses during deliberate hypotension with either esmolol or nitroprusside during steady-state n2o/isoflurane anesthesia. the first 5 patients were empirically assigned to the esmolol group; the remaining 20 patients were randomized to receive either esmolol or nitroprusside. the target of 15% reduction in mean arterial pr ...	2010	2908483
clinical, morphopathological and toxicological studies in acute benzodiazepine poisonings.		2010	2908774
lymphadenopathy of kimura's disease.	kimura's disease is an important category of reactive lymphadenopathy in the oriental population. the enlarged nodes are mostly located in the head and neck region. salient pathological changes include florid germinal centers, warthin-finkeldey type polykaryocytes, vascularization of germinal centers, increased postcapillary venules in the paracortex, eosinophilic infiltration, and sclerosis. the pathology of kimura's disease is quite different from that of angiolymphoid hyperplasia with eosinop ...	2010	2919716
precision excision of pulmonary metastases--a useful technique.		2010	2926757
mechanisms of inactivation of soybean lipoxygenase by acetylenic fatty acids.		2010	2936111
endocytosis of proteoheparan sulfate by cultured skin fibroblasts.	endocytosis by cultured human skin fibroblasts of 35so4(2-)-labeled proteoheparan sulfate from fibroblast secretions was quantitatively investigated. at a constant dose of proteoheparan sulfate, uptake and subsequent intracellular degradation but not binding to the cell membrane increased with time. compared with the endocytosis of total secreted proteoglycans containing predominantly a small proteodermatan sulfate, uptake of proteoheparan sulfate was 5- to 20-fold lower. nevertheless, uptake of ...	1986	2943303
morphine or capsaicin administration alters the secretion of beta-endorphin into the hypophysial portal vasculature of the rat.	immunoreactive beta-endorphin (ir-beta-end) concentrations were measured in the hypophysial portal plasma of the male rat under urethane anesthesia. on the basis of immunochemical studies and gel filtration chromatography it appears that ir-beta-end in rat hypophysial portal plasma is primarily beta-endorphin (beta-end) and not beta-lipotropin (beta-lph). in addition, much of the ir-beta-end in portal plasma may be of pituitary origin since acute hypophysectomy resulted in approximately an 80% d ...	1986	2944026
human milk-derived lactoferrin inhibits mitogen and alloantigen induced human lymphocyte proliferation.	purified lactoferrin (lf), isolated from human milk, was tested for its effect on human t-lymphocyte proliferative responses to phytohemagglutinin (pha) and to alloantigens in mixed lymphocyte culture. lf inhibited proliferation in both assays in a dose-dependent manner. the suppressive effect was not due to lf mediated cytotoxicity since washing cells that had been pre-incubated with lf restored their proliferative activity. lf was most effective in suppressing the pha response when added withi ...	1987	2963123
demonstration of a ouabainlike plasma compound in hypertension prone and hypertension resistant rats.	material extracted and partially purified from plasma of the sabra hypertension prone rats was found to be capable of 1) inhibiting the binding of 3h-ouabain to rat brain synaptosomes, 2) inhibiting the activity of rat brain microsomal na, k activated adenosine triphosphatase, and 3) increasing the contractile force of rat heart muscle. the results demonstrate the presence of a ouabainlike compound in the plasma of these rats. the plasma concentration of this compound in sabra hypertension prone ...	1985	2993163
[surgery in the treatment of patients with small cell lung cancer].	the data on surgical and combined treatment of 52 cases of small cell lung cancer are presented and the end results are evaluated. the findings on survival time make the case for surgery as a component of combined treatment of tumor. the best results were obtained in cases of stage i and ii tumor, absence of metastases into intrathoracic lymph nodes, tumor invasion limited to bronchopulmonary lymph nodes or the root of the lung, intermediate cell pattern of small cell lung cancer and surgery fol ...	2010	2998088
secretion of anti-müllerian hormone by immature bovine sertoli cells in primary culture, studied by a competition-type radioimmunoassay: lack of modulation by either fsh or testosterone.	secretion of anti-müllerian hormone (amh) by immature bovine sertoli cells in primary culture was studied through a competition-type ria employing a polyclonal antibody and 125i-labelled purified amh. this ria is approximately 10 times more sensitive than the solid-phase two-site monoclonal antibody-based ria described previously. biosynthesis and secretion of amh by cultured sertoli cells require approximately 48 h, are not influenced by fsh or testosterone and steadily decrease over a one-week ...	1985	3000849