Publications

sex specific oestrogen binding in the middle hypothalamus of rats.		1975	179802
malignant transformation-linked imbalance: decreased xanthine oxidase activity in hepatomas.	xanthine oxidase was decreased 2- to 10-fold in all examined rat hepatomas irrespective of the malignancy; growth rate and degrees of histological differentiation of the neoplasms. the affinity to substrate (km=6-8 mum) and the ph optimum (8.0) of the liver and hepatoma enzymes were the same. the reprogramming of gene expression, as manifested in the decreased activity of this key purine metabolizing enzyme, appears to be specific to neoplastic transformation. since glutamine prpp amidotransfera ...	1975	179860
polymeric collagen fibrils. an example of substrate-mediated steric obstruction of enzymic digestion.	polymeric collagen fibrils have been reacted with fluorescein and rhodamine isothiocyanates to produce fluorescent dye-labelled fibrils, containing seven dye substituents per molecule of tropocollagen within the polymeric collagen fibrils. two dye-labelled peptides per molecule of tropocollagen were solubilised by trypsin (ec 3.4.21.4) from the telopeptide regions and four dye-labelled peptides were located in the helical regions solubilised by bacterial collagenase (ec 3.4.24.3). the solubilisa ...	1994	186122
structural studies and physical maps for the herpes simplex virus genome.		1977	193820
guidelines on after care for denture patients. council on dental health.		2003	193879
paramagnetic anisotropy and zero-field splitting in tetraphenylporphyrinatoiron (iii) chloride.		2003	193882
[study of cytoplasmic rna in tissues of the rat, regenerating liver and in liver of rats with hepatoma pc-1].	cytoplasmic rna of the rat regenerating liver and liver of rats with hepatoma pc-1 is separated into five fractions on the column of kieselgur with methylated albumin (mak). studies in the nucleotide composition showed that certain fractions of cytoplasm rna are ribosomal and messenger rna. the highest amount of radioactive precursor is incorporated into messenger rna of the rat regenerating liver and liver of the rats with hepatoma pc-1 which is eluated from the column by 0.2% solution of sodiu ...	1977	201068
the presence of disulfide-linked gp70-p15(e) complexes in akr murine leukemia virus.		1977	201090
lysis of thrombus in internal carotid artery in the neck. report of a case.	a case report is presented demonstrating spontaneous lysis of clot in the internal carotid artery in the neck with surgical and angiographic documentation. the possible factors promoting thrombus formation and lysis are discussed. spontaneous lysis of a carotid thrombus occurred in 72 hours.	2003	207105
[angiotomography of supratentorial brain tumors].		2003	207124
influence of adrenocorticotropin on transport of a cholesteryl linoleate-low density lipoprotein complex into adrenal tumor cells.	the action of adrenocorticotropin (acth) on the specific (receptor-mediated) uptake of cholesteryl linoleate . low density lipoprotein complexes was examined in y-1 mouse adrenal tumor cells. high affinity binding (ka 4.1 x 10(8) m) was observed with acth; lower affinity was seen in the absence of acth. the effect of acth was observed within 10 min at physiological concentrations of low density lipoprotein (100 microgram/ml). binding was followed by uptake (internalization) of the ester . lipopr ...	1979	227899
a slowly dissociating form of the cell surface cyclic adenosine 3':5'-monophosphate receptor of dictyostelium discoideum.	experiments using a phosphodiesterase-minus mutant of dictyostelium discoideum indicate that ligand-induced loss of cell surface cyclic adenosine 3':5'-monophosphate binding sites (down regulation) can be evoked with concentrations of cyclic adenosine 3':5'-monophosphate as low as 10(-8) m. the loss of receptor sites is observed after 5 min of cell preincubation with cyclic adenosine 3':5'-monophosphate and can be as extensive as 75 to 80%. this decrease in binding sites is correlated with the a ...	1979	227901
[current point of burn patient care in france].		1995	228424
marek's disease lymphoma of chicken and its causative herpesvirus.		1979	228727
hormone-receptor interactions: corticotropin-(1-24)-tetracosapeptide spans artificial lipid-bilayer membranes.		1996	229037
isolation and partial biochemical characterization of the brush border plasma membrane from the cestode, hymenolepis diminuta.		1979	229204
nucleoside 3',5'-cyclic monophosphate metabolites of purine analogs. possible role as physiological mediators.		1997	229855
oxidation of fatty alcohols to acids in the caecum of a gourami (trichogaster cosby).	oxidation of fatty alcohols to acids in gourami caeca was investigated by measuring the reduction of nad+ and the formation of labeled hexadecanoic acid from [1(-14)c]hexadecanol. virtually all dehydrogenase activity is in the microsomal fraction. maximal activity is obtained with nad+ as cofactor whereas with nadp+ 60% of that activity is obtained. the enzyme is rather specific for long chain alcohols and 2 nadh are formed for each molecule of hexadecanol oxidized to acid. it is stabilized by m ...	1997	229908
[mucoviscidosis].		2003	254352
effects of althesin and its steroidal components on a variety of excised smooth muscle preparations.		1979	262472
influence of the substituent radicals in antimonyl naphthalein derivatives on the potentialities of anti-schistosomal activity in mice.		1979	262474
acute toxicity studies of some new organic trivalent antimonials.		2003	262475
genetic analysis of lines selected for wing vibration in drosophila melanogaster.	selection for the wing vibration component of courtship in the oregon-r stock of d. melanogaster was practiced for 44 generations. selection was successful, indicating that there is genetic variation for the trait in the oregon-r stock. the mean realized heritability of the trait, based on the first 11 generations of selection, was 15%. biometrical analysis showed that there is some additive genetic variance for the trait with the possibility of some ambidirectional dominance. no maternal effect ...	1993	262627
[birth rate, infant mortality and maternal mortality. chile 1964-77].		1994	262990
the measurement of bile acid-dependent and independent fractions of rat bile.	bile flow and bile acid secretory rate in rate in rats with interruption of the enterohepatic circulation had a biphasic decay with the second slower slope less marked for bile flow. a direct relationship between both parameters was observed in these animals. by knowing the choleretic efficiency of bile acids calculated from the regression line, the total bile acid output and the volume of bile collected, the fraction of bile produced by other way than bile water carried by bile acids was estima ...	1978	263162
nursing--an international perspective.		1994	263749
hard truths mean no soft options.		1994	263754
care of patient with stroke. role of primary physician.		1992	265010
aggressive juvenile fibromatosis involving the mandible: surgical excision with immediate reconstruction.	aggressive juvenile fibromatosis involving the facial bones is rare, difficult to diagnose clinically, histologically confusing, and requires aggressive surgical treatment. only four cases involving the mandible have been previously reported. a review of the literature is presented here in conjunction with a case report of this rare tumor.	1993	266144
surface ultrastructural response of the human uterine lining epithelium to hormonal environment. a scanning electron microscopic study.		1977	269610
plan now to ease the pain of tax decay.		1991	270425
the dental team. hygienist hotline.		1991	270436
therapy for infections due to anaerobic bacteria: an overview.	several classes of antimicrobial agents (e.g., penicillins, cephalosporins, tetracyclines, chloramphenicol, and clindamycin) are useful in treatment of infections due to anaerobic bacteria. however, certain anaerobic bacteria have shown a striking resistance to antimicrobial agents. in vitro susceptibility tests are useful for selection of optimal therapy. the choice of agent depends, to some extent, on the organisms responsible for the infection. bacteroides fragilis is the most commonly encoun ...	1977	321708
[the ovary and the immunity system].		1977	340059
human bone marrow colony formation in diffusion chambers. normal values.		1978	340240
[the control of renin secretion: experimental data and clinical implications].		2004	356832
nucleotide sequence of the ampicillin resistance gene of escherichia coli plasmid pbr322.	i have determined the nucleotide sequence of the ampicillin resistance gene of pbr322, an escherichia coli plasmid that encodes a penicillin beta-lactamase. this gene codes for a protein of 286 amino acid residues. the first 23 amino acids presumably form a signal for secretion, because they do not appear in the mature enzyme, whose partial amino acid sequence has been determined independently.	1978	358200
quantitative estimation of leishmanial antibody titers by enzyme-linked immunosorbent assay.	the response to immunization against leishmania braziliensis in rabbits was followed by measurement of antibody by enzyme-linked immunosorbent assay (elisa), passive hemagglutination, complement fixation, and countercurrent immunoelectrophoresis. passive hemagglutination and complement-fixation titers were interpreted according to standard methods, whereas elisa exact titers were derived by the equation y = a-b log x, which describes the straight line that results when absorbances are plotted ag ...	1979	387886
vitamin a deprivation and drosophila photopigments.		2004	404571
a case of missing justification in an audit of thyroidectomy.		2004	404608
colonic adrenocarcinomas in patients with ureterosigmoidostomies.	two additional cases of adenocarcinoma of the sigmoid colon occurring at the site of ureterosigmoidostomy are reported. the high risk of this complication occurring in patients who have undergone ureterosigmoidostomy is described. the possible shortness of the interval from diversion to development of an adenocarcinoma, especially in those cases involving carcinoma of the bladder, is emphasized. it is strongly recommended that careful follow up of such patients should begin within several years ...	2004	446246
[dynamics of the development of different microorganisms in soil].	the dynamics of individual components from the complex of soil microorganisms (bacteria, fungi, actinomycetes) and the population of stm. olivocinereus introduced into soil was studied by luminescent microscopy and inoculation. the population density maxima for individual components from the complex of soil microorganisms were shown to be separated in time suggesting a succession. fungi developed at the first steps of succession and dominated in biomass over the remaining components of the compl ...	1979	470632
ehrlichiosis in wolves, dogs, and wolf-dog crosses.	canine ehrlichiosis was diagnosed in wolves, dogs, and wolf-dog crosses at a small zoo in northcentral florida. five of 9 adult canids and all 8 pups confined to a common kennel died as a result of the infection. the epizootic was associated with a massive rhipicephalus sanguineus infestation. hematologic and pathologic findings in an adult wolf-dog cross that died were characteristic of canine ehrlichiosis. that animal and four other canids were seropositive for ehrlichia canis. no deaths occur ...	1979	521367
tomographic localization of motion axes.	localization of motion axes within joints and junctures in living humans has been carried out by means of roentgen stereophotogrammetry. another technique is presented here, in which the localization of the axis is carried out by means of tomography. the field of application for this technique has been examined in a series of phantom experiments. it may be employed in certain situations where roentgen stereophotogrammetry is not useful. no other equipment is needed than a pluridirectional tomogr ...	2004	525421
[vascular surgery in the aged].		2005	538948
[post-cholecystectomy condition: duodeno-gastric reflux and bile acid concentration in the gastric juice].	in cholecystectomized patients highly significantly more frequently a duodenogastric reflux was found than in a group of patients with a healthy abdomen and a group of patients with cholelithiasis. the average concentration of bile acid in the gastric juice was after the removal of the gall-bladder manifoldly higher than in the control groups. the number of patients with concentrated reflux was also highly significantly larger than in patients with cholelithiasis not operated on and in patients ...	2005	538988
[gastric secretion in gastroduodenal ulcer].		2005	545511
[cutaneous evaporimetry. iii. cutaneous water loss (cwl) in the suckling infant].		2005	548079
the brown dog tick rhipicephalus sanguineus and the dog as experimental hosts of ehrlichia canis.	adult rhipicephalus sanguineus ticks efficiently transmitted ehrlichia canis to susceptible dogs for 155 days after detachment as engorged nymphs from a dog in the acute phase of ehrlichiosis. adult ticks that had similarly engorged on a dog in the chronic phase of ehrlichiosis failed to transmit e canis to susceptible dogs. infected but unfed adult ticks may be of greater importance than the chronically infected carrier dog as a natural reservoir of e canis.	1977	596693
retrospective study of an ehrlichia canis epizootic around phoenix, arizona.	antibodies to ehrlichia canis were detected by indirect immunofluorescence in sera from 40 of 339 dogs (12%) examined from around phoenix, az, during 1975. the prevalence was higher in purebred and crossbred german shepherd dogs (21%), as compared with 8% in the remaining breeds. the difference in antibody prevalence between sexes was not significant. dogs 12 weeks to 13 years old were seropositive. the causative agent was isolated by inoculation of whole blood from a seropositive dog into a sus ...	1978	624663
cyclic thrombocytopenia induced by a rickettsia-like agent in dogs.	hematologic manifestations and the ultrastructure of a platelet-specific microorganism isolated from a dog in florida were studied. the agent was readily transmitted experimentally to adult dogs by intravenous inoculation with infected blood. parasitemias and concomitant thrombocytopenias were cyclic in that both recurred within relatively constant periods of one to two weeks following experimental infections. hemorrhage was not a manifestation of the disease even though thrombocytopenias were s ...	1978	627738
effect of canine immune serum on the growth of ehrlichia canis within nonimmune canine macrophages.	the effect of canine immune serum (cis) on the growth of ehrlichia canis was studied in macrophage cultures derived from peripheral blood monocytes of normal dogs. ehrlichiae treated with canine normal serum and then introduced into normal macrophage cultures maintained in canine normal serum multiplied within the macrophages and destroyed them. immune serum, collected from e canis carrier dogs, suppressed ehrlichial growth in normal macrophages. an inverse relationship existed between the amoun ...	1978	629451
effect of canine immune macrophages and canine immune serum on the growth of ehrlichia canis.	the effect of canine immune macrophages and canine immune serum (cis) on the growth of ehrlichia canis was studied in vitro. treatment of e canis organisms with cis before they were inoculated into immune macrophage cultures, coupled with pre- and postinoculation maintenance of cultures in cis, suppressed macrophage infection rates to 1% or less. immune macrophages collected from e canis-carrier dogs and maintained in canine normal serum were more resistant to the intracellular growth of e canis ...	1978	629452
prophylactic and therapeutic use of tetracycline during an epizootic of ehrlichiosis among military dogs.	an epizootic of canine ehrlichiosis at the military working dog center, pakchong, thailand, was arrested by prophylactic and therapeutic use of tetracycline and by control of ticks. oral treatment with tetracycline (66 mg/kg of body weight daily for 14 days) effected remission of signs of disease in 60 of 62 clinically affected dogs and resulted in disappearance of serum antibody in 119 (60%) of 198 seropositive dogs treated during the 2-year study period. transmission of ehrlichia canis was int ...	1978	640933
autologous lymphocyte-mediated cytotoxicity against monocytes in canine ehrlichiosis.	the 51cr-release technique for detecting cytotoxicity had been adapted to immunologic studies of canine ehrlichiosis. lymphocytes from dogs infected with ehrlichia canis, cause of canine ehrlichiosis, were shown to be cytotoxic for autologous monocytes. the effect was dependent on the concentraton of lymphocytes, being optimal at 100:1 lymphocyte:monocyte ratio. neither immune serum and complement, nor anti-canine globulin had any observable effect on cytotoxicity. the monocytotoxicity bore a te ...	1977	931138
canine peritoneal macrophages: cultivation and infection with ehrlichia canis.	canine peritoneal macrophages were obtained by repeated peritoneal lavage of dogs at 14 day intervals. intraperitoneal administration of sterile mineral oil increased the leukocyte yield approximately 20-fold and the macrophage recovery approximately 35-fold. cell recovery was maximum 7 to 21 days after administration of oil and declined slightly by 35 days. restimulation with a 2nd injection of oil promptly revitalized cell recovery. peritoneal macrophage cultures were well established by 6 day ...	1977	931165
acute canine ehrlichiosis: platelet survival and factor 3 assay.	ten dogs experimentally inoculated with ehrlichia canis were thrombocytopenic 14 days after inoculation. circulating platelet concentrations had declined rapidly by postinoculation day 10, but remained at or slightly below the 14-day concentration during the remainder of the 42-day experimental period. the percentage of circulating megathrombocytes also increased to 8.7 times preinoculation concentrations indicating the existence of accelerated thrombocytopoiesis. the release of platelet factor ...	1977	931166
development of ehrlichia canis, causative agent of canine ehrlichiosis, in the tick rhipicephalus sanguineus and its differentiation from a symbiotic rickettsia.	certain aspects of the development of ehrlichia canis, causative agent of canine ehrlichiosis (tropical canine pancytopenia) in rhipicephalus sanguineus ticks were studied. it was found that partial feeding of nymphs infected as larvae with e canis was a desirable, if not necessary, preliminary treatment for successful infection of dogs with ground-up ticks. it remains unclear whether feeding increased the number or altered the virulence of ehrlichiae within tick tissues. ehrlichia canis organis ...	1976	944000
identification of ehrlichia canis in east africa.	ehrlichia canis, the causative agent of canine ehrlichiosis or tropical canine pancytopaenia (tcp) has been identified in kenya. transmission studies to two dogs resulted in signs of ehrlichiosis including marked thrombocytopaenia, pyrexia, reduction in the packed cell volume and the presence of e canis in peripheral blood mononuclear cells.	1976	997191
duplication of radiographs.		2005	1074385
[resection of chondrosarcoma of the sternum with restoration of the thoracic wall. report of a case].		2005	1081246
pre- and postnatal enzyme capacity for drug metabolite production.	most lipid-soluble foreign compounds including drugs, insecticides and many environmental pollutants are metabolized in animals by cytochrome p-450 enzymes in the endoplasmic reticulum of liver. these enzymes are virtually absent in fetuses of laboratory animals, but their activities increase to adult levels within 3-8 weeks after birth. in human fetuses, the enzymes appear during the first half of pregnancy, and their activities during gestation reach about one third of those found in adults. t ...	1975	1090453
isolation in illinois of a foreign strain of ehrlichia canis, the causative agent of canine ehrlichiosis (tropical canine pancytopenia).	ehrlichiosis (tropical canine pancytopenia) was diagnosed in illinois in a 4 1/2-year-old mixed breed dog that had spent the previous 2 years in india. the dog had periodic epistaxis, anemia, leukopenia, hypoalbuminemia, and hypergammaglobulinemia. a titer of 1:160 for ehrlichia canis was detected by the indirect fluorescent antibody test (ifat). subinoculation of blood into a clinically normal dgo resulted in typical signs of canine ehrlichiosis, and e canis was identified in circulating mononu ...	1975	1112743
experimentally induced infection of dogs, cats, and nonhuman primates with ehrlichia equi, etiologic agent of equine ehrlichiosis.	dogs (german shepherd dogs and beagles), cates, rhesus macaques (macaca mulatta), and baboons (papio anubis) were inoculated with whrlichia equi, the etiologic agent of equine ehrlichiosis. within 3 to 7 days after inoculation, morulae were observed in the eosinophils of cats, neurtrophils of macaques and baboons, and in both neutrophils and eosinophils of dogs. the severe disease produced in horses by this agent was not a feature of e equi infection in dogs, cats, macaques, and baboons. however ...	1975	1115421
platelet kinetics in canine ehrlichiosis: evidence for increased platelet destruction as the cause of thrombocytopenia.	a significant (p < 0.025) increase in the mean platelet diameter occurred in five ehrlichia canis-infected dogs when platelet numbers decreased to 100,000/mul or less. maximal incorporation of [(75)se]selenomethionine into platelets of six uninfected dogs was 0.080 +/- 0.019% (mean +/- standard error) and occurred 5 to 6 days after dosage, whereas maximal incorporation was 0.036 +/- 0.004% within 2 to 3 days after dosage in seven chronically infected dogs that had thrombocytopenia. analysis of t ...	1975	1140846
transmission of ehrlichia canis to dogs by ticks (rhipicephalus sanguineus).	two strains of rhipicephalus sanguineus acquired ehrlichia canis by feeding as either larvae or nymphs on acutely infected dogs and, in subsequent instars, transmitted the agent to normal dogs. three strains of r sanguineus transmitted e canis as adults after their larval and nymphal stages fed on infected dogs. more than 400 adult female ticks were fed on infected dogs as larvae or nymphs or both, but none transmitted e canis transovarially.	1975	1147359
ehrlichia canis infection in a dog in virginia.		1975	1150498
phobic response factors from the fear survey schedule.	a phobic response scale was factored from responses to the fear survey schedule. subjects were 137 male and 168 female college students. a six factor solution extracted 41.78% of the trace. the factors were as follows: i (hostile-dependence), ii(body assult), iii (developmental fears), iv (performance and evaluation), v (death evasion), and vi (nuisance animals). an analysis of sex differences by item and scale generally supported and extended previous research. some conceptual ties were made by ...	2005	1151900
clinical evaluation of tumor scanning with 169-yb-citrate.	169-yb-citrate was used as the tumor-scanning agent in 360 patients with malignant tumors and in 55 others with benign lesions and the results compared with 67-ga-citrate studies in other series. in malignant tumors, the overall positive detection rate for ytterbium was 65.3%; in benign lesions, the false-positive rate was 29.1%. good results were obtained in the extremities, head and neck, and pelvic area. of all tumors visualized, squamous cell carcinoma was detected most effectively (77.5%). ...	2005	1153741
[abo blood groups in gastric cancer].		2005	1169525
psychiatric morbidity in a sample of a london coroner's open verdicts.	one hundred and thirty-four deaths recorded as open verdicts in the inner west london coroner's district during 1969 and 1970 have been surveyed for evidence of mental illness. for 110 (82 per cent) of these deaths the probable verdicts were suicide or accident and they were reclassified as undetermined deaths. of these deaths 73 per cent were diagnosed as mentally ill, 54 per cent were receiving medical treatment for psychological symptoms before death, 42 per cent had a history of psychiatric ...	2005	1182365
ripple suppression during reconstruction in transverse tomography.		2005	1187793
payments to policyholders and beneficiaries exceed four billion dollars.		2005	1273867
interleukin-1 inhibits pge2 binding to macrophage-like p388d1 cells by a cyclic amp-independent process.	the interaction between interleukin il-1 alpha and pge2 on p388d1 cells has been investigated. preincubation of murine macrophage-like cells, p388d1, with il-1 alpha (0-73 pm) reduced the binding of pge2 to these cells in a concentration-dependent manner. scatchard analysis showed that il-1 alpha decreased the pge2 binding by lowering both the high and low affinity receptor binding capacities (from 0.31 +/- 0.02 to 0.12 +/- 0.01 fmol/10(6) cells for the high affinity receptor binding sites and f ...	2005	1310627
ehrlichia canis infection in a child in south carolina.		1992	1319878
a common precursor for cd4+ t cells producing il-2 or il-4.	to investigate whether cd4+ t cells are predetermined to produce a given pattern of lymphokines, we have used a culture system that allows the controlled induction of either il-2- or il-4-producing cd4+ t cells. single, freshly isolated murine cd4+ t cells were activated with con a, ril-2, and apc; the developing clones were split and then cultured for an additional 14 days with either ril-2 alone or with ril-2 and anti-cd3 stimulation. subclones expanded in the presence of ril-2 alone produced ...	2006	1346619
rediscovering wormwood: qinghaosu for malaria.		2006	1347342
an enhanced-response system for performing chemiluminescent and bioluminescent tests.		2006	1366493
phylogenetic position of cowdria ruminantium (rickettsiales) determined by analysis of amplified 16s ribosomal dna sequences.	the 16s ribosomal dna sequence of cowdria ruminantium, the causative agent of heartwater disease in ruminants, was determined. an analysis of this sequence showed that c. ruminantium forms a tight phylogenetic cluster with the canine pathogen ehrlichia canis and the human pathogen ehrlichia chaffeensis. although a close relationship between the genus cowdria and several members of the tribe ehrlichieae has been suspected previously, the tight phylogenetic cluster with e. canis and e. chaffeensis ...	1992	1380292
site of injection for vaccination.		2006	1392898
chronic diarrhoea due to strongyloidiasis in a nigerian with chronic renal failure: a case report.	a case of chronic diarrhoea due to infection with strongyloides stercoralis in a nigerian patient with chronic renal failure is presented. due to the potential for fatal outcome in this infection, strongyloidiasis should be kept in mind as a cause of chronic diarrhoea in chronic renal failure patients in endemic areas.	1992	1404562
combined effects of ethanol and protein deficiency on hepatic iron, zinc, manganese, and copper contents.	the present study has been performed in order to establish the relative and combined roles of ethanol and malnutrition on liver fe, zn, cu, and mn alterations in alcoholic male adult wistar rats, and also the relationships between these alterations and histomorphometrically determined hepatocyte and nuclear areas, perivenular fibrotic rim area, and total amount of fat present in the liver. four groups of 8 animals each were fed: (1) a nutritionally adequate diet (c); (2) a 36% ethanol-containing ...	1992	1418656
"raynaud's disease" in migraineurs: one entity or two?	two cases are reported of patients who were diagnosed as having both migraine and raynaud's disease. because they were able to achieve effective control of both headaches and extremity temperature after undergoing a comprehensive approach--utilizing medication, biofeedback, and psychotherapy--it is suggested that both conditions are manifestations of the same disorder. it is recommended that a first step in approaching concurrent diagnoses of this type involve combined treatment as is often used ...	2006	1446993
investigation of glomerular lesions in dogs with acute experimentally induced ehrlichia canis infection.	six male beagles were inoculated with ehrlichia canis. transient proteinuria was confirmed during the acute phase of infection by serial determination of urinary protein-to-creatinine ratio. peak urine protein loss, consisting principally of albumin, was observed 2.5 to 3.5 weeks after inoculation. renal biopsy specimens were obtained before inoculation, during peak proteinuria, and 10 weeks after inoculation when proteinuria had resolved. renal tissue was evaluated by use of light, immunofluore ...	1992	1476309
characterization of disulfide-linked heterodimers containing apolipoprotein d in human plasma lipoproteins.	human plasma apolipoprotein (apo) d is a glycoprotein with an apparent molecular weight of 29,000 m(r). it is present, mainly, in high density lipoproteins (hdl) and very high density lipoproteins (vhdl). western blot analysis of hdl and vhdl using rabbit antibodies to human apod revealed major immunoreactive bands at 29,000 and 38,000 m(r), with minor bands ranging from 50,000 to and 80,000 m(r). only the 29,000 m(r) band corresponding to apod remained when the electrophoresis was conducted und ...	1992	1479288
supporting collaboration through a nursing informatics curriculum stage ii.	collaboration is at the center of the process used to design, implement and evaluate an integrated informatics curriculum in a baccalaureate nursing program. this paper describes the second stage of a process to design the informatics nursing courses. the challenges to foster faculty collaborative relationships as well as to enhance the course content of all nursing informatics curriculum. a number of strategies were used to develop the collaborative efforts between the faculty and nursing staff ...	2006	1482910
evaluation of granulocytic ehrlichiosis in dogs of missouri, including serologic status to ehrlichia canis, ehrlichia equi and borrelia burgdorferi.	canine granulocytic ehrlichiosis was diagnosed in 37 dogs by finding ehrlichial morulae in 0.1 to 26.2% of their blood neutrophils and eosinophils. all 37 dogs had clinical signs of arthritis or muscular stiffness. titer to ehrlichia canis was determined in sera from 31 of the 37 dogs; 25 dogs had titer ranging from 1:20 to 1:5,120. in the other 6 dogs, titer to e canis was less than 1:10. the most common hematologic abnormality in these dogs, other than rickettsiemia, was thrombocytopenia. gran ...	1992	1539918
primary fibrinogenolysis complicating second trimester placental separation.	we present a case of second trimester placental separation complicated by severe bleeding diathesis. primary fibrinogenolysis is suggested as the cause of the coagulopathy.	2006	1550391
[why do physicians and patients ever more often resort to practitioners of alternative medicine: the healer and the quack?].		2006	1563606
ehrlichia ewingii sp. nov., the etiologic agent of canine granulocytic ehrlichiosis.	the 16s rrna gene was amplified, cloned, and sequenced from the blood of two dogs that were experimentally infected with the etiologic agent of canine granulocytic ehrlichiosis. the 16s rrna sequence was found to be unique when it was compared with the sequences of other members of the genus ehrlichia. the most closely related species were ehrlichia canis (98.0% related) and the human ehrlichiosis agent (ehrlichia chaffeensis) (98.1% related); all other species in the genus were found to be phyl ...	1992	1581189
antigenic characterization of ehrlichiae: protein immunoblotting of ehrlichia canis, ehrlichia sennetsu, and ehrlichia risticii.	in recent years a febrile illness apparently associated with tick bite in patients in the united states has been attributed to infection by an ehrlichia species. this implication is based on serologic responses to e. canis, morphologic demonstration of ehrlichiae in clinical materials, and a single isolate distinct from e. canis which was obtained from a human patient by the centers for disease control. little is known about the antigens of the ehrlichiae. this report expands the breadth of avai ...	1992	1583101
investigation of renal protein loss in dogs with acute experimentally induced ehrlichia canis infection.	urinary protein-to-creatinine ratios and serum albumin concentrations were measured in 8 adult male dogs experimentally inoculated with ehrlichia canis. urinary protein concentration increased significantly, but transiently, during the acute phase of infection. urinary protein-to-creatinine ratios were highest (mean, 8.6) during the third and fourth weeks after infection, and decreased to less than 0.5 by 6 weeks after infection. correspondingly, albumin concentration decreased significantly dur ...	1992	1595954
[digestive hemorrhage caused by aorto-duodenal fistula. report of 5 cases].	the aortoduodeonal fistula is a rare condition and has high mortality. we report five retrospective cases of digestive hemorrhage due to an aortoduodenal fistula (4 secondary and 1 primary) between 1986 and 1990. three of them died. attention is called to the importance of clinical suspicion and the main diagnostic methods in early diagnosis such as oral endoscopy. we also enhance the importance of emergency surgery for survival.	2006	1599763
[hemodilution therapy in peripheral arterial occlusive disease].		2004	1618610
infection due to ehrlichia canis in children.	human ehrlichiosis has a wide spectrum of presentation. this report presents two cases that demonstrate the diversity of the manifestation of ehrlichiosis, from life threatening to a mild viral-like illness. diagnosis requires an understanding of the epidemiology and clinical manifestation of this infection and a high index of suspicion.	1992	1631682
myocardial entrapment by lymphoma: a cause of reversible segmental left ventricular dysfunction.		2006	1636600
human pathogenicity of ehrlichia canis.		1991	1674051
structural probing of human lutropin using antibodies raised against synthetic peptides constructed by classical and multiple antigen peptide system approaches.	antibodies were elicited against a synthetic peptide which encompassed two different regions of the human lutropin beta-subunit (hlh-beta). these antibodies were raised against either the peptide which was assembled using a conventional approach and conjugated to the tetanus toxoid, or with the peptide assembled using the multiple antigen peptide system approach. automated simultaneous synthesis of the two forms of the immunizing peptide was successfully achieved. animal injected with the peptid ...	1990	1694262
analyses of ehrlichia canis and a canine granulocytic ehrlichia infection.	ehrlichia canis and canine granulocytic ehrlichia sp. (cge) infect canine monocytes and granulocytes, respectively. e. canis has been cultured in vitro and used to develop an immunofluorescence assay. cge has not been cultured, and a serologic assay is not available. the sera of dogs infected with cge were reported to react with e. canis by immunofluorescence. in this study, the temporal response of immunoglobulin g (igg) was determined by an enzyme-linked immunosorbent assay (elisa) with purifi ...	1992	1734046
antigenic and genomic relatedness among ehrlichia risticii, ehrlichia sennetsu, and ehrlichia canis.	antigenic and genomic relatedness among ehrlichia risticii, e. sennetsu, and e. canis was analyzed by enzyme-linked immunosorbent assay, western blotting (immunoblotting) and dna-dna hybridization. e. risticii and e. sennetsu were serologically related, and their western blot antigen profiles were nearly identical. two antigens of e. sennetsu corresponding to the 28- and 51-kda antigens of e. risticii were apparently larger than the e. risticii antigens, and the 55-kda antigen of e. risticii app ...	1992	1736961