Publications

ability of insulin to increase calcium binding by adipocyte plasma membranes.	calcium specifically binds to adipocyte plasma membranes, demonstrating two classes of binding sites having affinity constants of 4.5 x 10(4) m-1 and 2.0 x 10(3) m-1. insulin (100 microunits/ml) added directly to the isolated plasma membranes caused no alteration in calcium binding, whereas incubation of the adipocytes with 100 microunits/ml of insulin resulted in a 2.50 +/- 1.6% increase in calcium binding to the subsequently isolated plasma membranes. the increase in calcium binding produced b ...	1976	1064022
[cysts and fistulas of embryonal origin of the face].		2005	1064061
gonadotropin-stimulated uptake of steroid hormones by rana pipiens ovarian follicles incubated in vitro.		2005	1082831
surgical treatment of bronchiectasis in kartagener's syndrome.	a case of kartagener's syndrome in which bilateral partial pulmonary resection was performed is reported. the literature concerning the surgical treatment of severe bronchiectasis is reviewed.	2002	1084204
the apical a wave versus the fourth heart sound in assessing the severity of aortic stenosis.	the height of the "a" wave of the apexcardiogram was evaluated as a marker for critical aortic stenosis in patients over 40. critical aoritc stenosis was defined as an aortic valve area less than .75 cm-2 with no more than mild aortic insufficiency. phonocardiograms and apexcardiograms were performed on 72 patients with catheterization proven aortic stenosis and on 14 normal controls, all over age 40. the height of the "a" wave of the apexcardiogram was measured as a percentage of the e to o exc ...	2005	1112012
improved methodology and precision using a straight base line technique for the quantitation of proteins by two dimensional immunoelectrophoresis.		2005	1112067
pattern and depth discrimination from random dot stereograms.	the discrimination of depth and pattern was investigated using random dot stereograms. for all four subjects, the psychometric function for depth judgments (probability of correct response) was clearly superior to pattern judgments over a range of ten crossed or uncrossed binocular disparity values. degrading the visual images, either monocularly or binocularly, with various convex lens power (fogging lenses) reduced both depth and pattern discrimination across all disparity values, rather than ...	2005	1130488
demonstration of ebstein's anomaly by simultaneous catheter-tip localization of the tricuspid valve visualization: a new method.	the diagnosis of ebstein's anomaly has traditionally been made by angiocardiography and confirmed by simultaneous intracardiac electrocardiographic and pressure recordings. these techniques may result in false positive or negative tests. a new method is proposed, whereby the right coronary artery is used an an angiographic marker for the tricuspid annulus and a pressure catheter simultaneously marks the position of the tricuspid valve. in the right anterior oblique position the tip of the pressu ...	1990	1149541
editorial: assessment of left ventricular function in chronic obstructive pulmonary disease.		1990	1149542
comparative antihypertensive effects and tissue distribution of beta adrenergic blocking drugs.	the precise mechanism of the antihypertensive action of beta adrenergic blocking drugs is not known. both peripheral and central sites of action have been proposed. the comparative antihypertensive actions and tissue distribution of propranolol, pindolol and sotalol were investigated in both normotensive sprague-dawley and spontaneously hypertensive rats. from recordings of concurrent changes in blood pressure and heart rate it was observed that oral or subcutaneous administrations of both propr ...	1975	1151751
[air embolism of cerebral vessels following self mutilation treated with hyperbaric air in a high-pressure chamber].		1986	1153060
[tremaril in the treatment of parkinsonism].		1986	1153061
femoral percutaneous catheterization in infants and small children for cerebral angiography.	an improved technique of selective cerebral angiography for infants and small chicken is described. the needle is inserted approximately 45 degrees to the skin in order to avoid subintimal placement of the tip. after good backflow is established, the guidewire is advanced to a position in the descending aorta. a no. 3 polyethylene catheter and 21-gauge scalp vein needle were most successful.	1975	1153751
part ii: the photic environment of clear tropical seas during the day.		2005	1166605
failure to consult specialist.		2005	1173090
letter: regulation of medical practice by government.		2005	1178002
xeromammography at a community hospital. a year's experience.		2005	1183210
verbal effects in children's visual recognition memory.	preschool children were shown line drawings of 12 pairs of items and were asked to describe them. each child saw elaborated and unelaborated pictures (items interacting vs. not interacting). the children's descriptions were rated as elaborated or unelaborated (interactions mentioned vs. not mentioned). 1 week later, a recognition test was given, with choices between an elaborated and an unelaborated picture for each pair. in general, recognition accuracy was best for elaborated pictures given el ...	2005	1183272
osteomyelitis in infants and children. a review of 163 cases.	one hundred sixty-three cases of osteomyelitis in infants and children were seen at our hospital during the past 15 years. there were twice as many boys as girls. staphylococcus aureus was the major etiologic agent, being identified in 61% of the cases. gram-negative bacteria were responsible for only 14 cases (9%). the femur, the tibia, or the humerus were affected in 103 of the 152 patients with single bone involvement. ostoemyelitis of more than one bone was seen in 11 cases (7%). associated ...	1975	1190158
the effect of iodine deficiency on thyroid function in the infant rat.	we have studied rats born to severely iodine-deficient mothers and subsequently maintained on a low-iodine diet (lid) from birth to 41 days. they were compared with controls born to mothers fed a high-iodine diet (hid). lid babies from birth on had large goiters, high thyroid labeled mit/dit ratios and radioiodine uptakes, high plasma tsh and low plasma t4 in comparison to hid controls. thyroid labeled t3/t4 ratios were low in all babies at birth but were higher in the lid than hid babies from d ...	1975	1196133
synchronization of the fission yeast schizosaccharomyces pombe using heat shocks.		1975	1196141
phloroglucinol derivatives of eleven dryopteris species from japan.		2005	1197418
[radiotherapy in the cancer of the rectum (author's transl)].		2005	1199662
the intercellular content of the three transcobalamins at various stages of normal and leukaemic myleoid cell development.	a study of the three serum transcobalamins (tc) in myeloproliferative disorders and acute leukaemia has suggested a granulocyte origin for the three binders; the later stages of this cell line might be releasing 'tc i' and 'tc iii' while 'tc ii' which is increased in sera from patients with acute myelogenous leukaemia, probably originates at least in part from myeloblasts. the intracellular content of each tc has been studied in normal and leukaemic bone marrow cells after separation on a discon ...	1975	1201243
micronodular encephalitis and acute leukemia treated with immunosuppressives in a child.	the present paper is the study of a micronodular encephalitis with inclusions occurring in a child suffering from acute leukemia treated with antimitotics and immunosuppressives. the role of the immunosuppressive treatment in the onset of the encephalitic syndrome is discussed.	2005	1242214
[practical evaluation of methods in pharmacokinetics].	a short discussion of the differences between kinetic processes of zero and first order is followed by an outline of evaluation methods used in pharmacokinetic practice, e.g. "paper and pencil methods" as well as the use of digital and analog computers. the increasing potency of new drugs requires not only more sophisticated methods of analysis and expensive facilities but also more complex models to generate pharmacokinetic information.	2005	1242344
the small for dates infant.		2005	1245399
linkage studies between hl-a and gpt polymorphisms and other genetic markers.	the phenotypes of 56 families with 126 children from the hamburg area as well as gene frequencies and segregation of the genetic markers gpt, ap, ada, ak, pgm1, pgm3, 6-pgd, che, c3, gc, tf, hp and cp were studied. in regard to linkage, the informative families were correlated to the results of hl-a and gpt typing. the linkage was tested according to the sequential test by morton (1955). see article. for other gene loci, linkage to the hl-a or gpt system could not be proved. but the positive lod ...	2005	1251571
attenuated, streptomycin-dependent salmonella typhi oral vaccine: potential deleterious effects of lyophilization.	four studies were done with streptomycin-dependent salmonella typhi as an oral, attenuated vaccine. studies 1 and 3 employed freshly harvested vaccine, whereas studies 2 and 4 involved lyophilized vaccine. five to eight doses (3 x 10(10)-10(11) organisms/dose) were given; oral streptomycin (1.0 g) was administered concomitantly in studies 2 and 3, with only two of the doses of vaccine in study 1, and was not given in study 4. no adverse reactions were encountered in 179 vaccinated men, and 94% o ...	1976	1262709
hydrocelectomy. evaluation of technique.	a quick, simple, safe, and efficient means of hydrocelectomy is presented. the technique consists of extruding and fixing the testicle into a scrotal pouch. twenty hydroceles were repaired without complication or recurrence.	2005	1265943
[methods of studying the electrical activity of the stomach and duodenum].		1976	1272972
[therapeutic effect of complamine in atherosclerosis and ischemic heart disease].		2005	1273633
construction and characterization of a single polypeptide chain containing two enzymatically active dihydrofolate reductase domains.	a single polypeptide chain containing two dihydrofolate reductase (dhfr) sequences from escherichia coli was constructed to determine if a repeat sequence fusion protein could be expressed in an active form. the possibility that intersequence interactions could play a significant role for this enzyme is suggested by the results of hall and frieden (1989, proc. natl acad. sci. usa, 86, 3060-3064) who observed a substantial decrease in the yield of active enzyme when folded in the presence of a la ...	1992	1287660
[treatment and monitoring of primary hypothyroidism].	treatment of primary hypothyroidism requires a long-term hormonal therapy with levothyroxine which restores a normal tsh value. in a series of 192 patients followed up for at least 3 years we tried to evaluate the variability of maintenance dosage and to analyse the factors predictive of replacement dosage. the l-t4 dosage varied from one individual to the other, from 0.6 to 3.2 micrograms/kg. the mean maintenance dosage (118 +/- 38 micrograms/day) was similar in men and women weight for weight, ...	1992	1287777
analysis of cell surface antigens of campylobacter rectus.	campylobacter rectus is one of the predominant bacteria in the lesions of human periodontitis. the surface antigens of the bacterium contain several components which may play significant roles in colonization and pathogenesis. a high-molecular-weight protein was selectively isolated from the cell surface of c. rectus by acid extraction and purified by deae sepharose. sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis showed that the extracted protein was 150 kda. the protein was ...	1992	1303324
characterization of the structure and properties of the his 62-->ala and arg 38-->ala mutants of yeast phosphoglycerate kinase: an investigation of the catalytic and activatory sites by site-directed mutagenesis and nmr.	the role of two "basic patch" residues, arg-38 and his-62, in the catalytic function and anion-dependent activation of yeast 3-phosphoglycerate kinase (pgk) was investigated by site-directed mutagenesis. steady-state kinetics and nmr experiments were conducted to characterize the functional properties and structural integrity of the r38a and h62a mutants. the results of these studies, in combination with earlier mutagenesis experiments, suggest that arg-38 is the only catalytically essential res ...	1992	1304916
job sharing: a viable option.		2004	1304937
expression and release of neuroregulators during development: monoamines and neuropeptides.	the turnover of catecholamines (ca) was determined in the adrenal medulla and brain of rat fetuses and pups. in general we found a considerable increase soon after birth. the expression of mrna for ca-synthesizing enzymes was also considerably enhanced in the adrenals shortly after birth. furthermore, we demonstrated increased expression of neuropeptides after birth, increased synthesis of mrna encoding for neuropeptide y in the adrenals 24 h after birth; and considerable activation of the subst ...	1992	1306802
gap-43 mrna localization in the rat hippocampus ca3 field.	gene expression of the axonal growth-associated protein, gap-43, has been studied in the adult rat brain by in situ hybridization histochemistry. this protein is synthesized at high levels in neuronal somata in immature and regenerating neurons, but after establishment of mature synaptic relations its synthesis generally declines sharply, thus providing a marker denoting propensity for exhibiting synaptic plasticity. detailed examination of the distribution of mrna for gap-43 in rat hippocampus ...	1992	1317499
the pathogenicity of drug-resistant variants of herpes simplex virus.		1992	1317602
multiple rearrangements and activated expression of c-myc induced by woodchuck hepatitis virus integration in a primary liver tumour.	woodchuck hepatitis virus (whv) is a small, partially double-stranded dna virus. like the related human hepatitis b virus (hbv), whv induces acute and chronic hepatitis and hepatocellular carcinoma (hcc) in its natural host. whv dna integration into c-myc and n-myc, resulting in deregulated expression of these genes, has been described previously in woodchuck hcc. we have analysed a woodchuck liver tumour in which whv dna was integrated in the c-myc gene. the virus insertion provoked multiple al ...	1992	1317604
an immunochemical and immunocytologic study of the increase in myometrial gap junctions (and connexin 43) in rats and humans during pregnancy.	myometrial gap junctions are thought to play a necessary role in control of parturition. in this study we evaluated the presence of gap junctions in myometrial tissues with a specific antibody to the gap junction protein, connexin 43, with immunocytochemistry and immunoblots. immunofluorescence of rat heart showed gap junctions were localized along the intercalated disks, but no change occurred during pregnancy. fluorescent staining of rat myometria showed punctate staining of gap junctions betw ...	1992	1323215
[paramedical personnel in psychiatry: specifics of training in a military teaching hospital].		2005	1343486
thymocytopoiesis is maintained by blood-borne precursors throughout postnatal life. a study in parabiotic mice.	this study was designed to resolve the long standing controversy as to whether hematogenous precursors or resident intrathymic precursors maintain thymocytopoiesis in postnatal life. the kinetics of thymic chimerism was examined over a 21-wk period in 105 pairs of nonirradiated, thy-1-alloantigen-disparate, parabiotic b10.s mice. thymic chimerism reached reached maximum levels of 25% in the thy-1b and 16% in the thy-1a partners (mean 20.5% and 9.8%, respectively) 6 to 7 wk after parabiotic union ...	2006	1347301
soluble tnf and membrane tnf expressed on cd4+ t lymphocytes differ in their ability to activate macrophage antileishmanial defense.	in our studies of host defense against the intracellular parasite leishmania major, we obtained evidence for a novel mechanism of macrophage activation for antimicrobial defense that involves direct cell contact between cd4+ t lymphocytes and leishmania-infected macrophages. the mechanism is distinctive as it does not involve secretion of lymphokines but is apparently mediated by the membrane-anchored form of tumor necrosis factor (mtnf; approximately 50-60 kd) present on the surface of the effe ...	1992	1347312
modulation of adhesion molecules on human large granular lymphocytes by interleukin-2 in vivo and in vitro.	the modulation of adhesion molecules on human large granular lymphocytes (lgl) by interleukin (il)-2 was investigated both in vivo and in vitro. intercellular adhesion molecule-1 (icam-1; cd54) expression increased on lgl of cancer patients receiving il-2 adoptive immunotherapy. icam-1 expression on lgl isolated by percoll gradient centrifugation, lgl purified, and expanded by adherence to plastic surfaces and lgl identified by leu 19 (cd56) monoclonal antibody were increased significantly in re ...	1992	1347485
location of the basal disk and a ringlike cytoplasmic structure, two additional structures of the flagellar apparatus of wolinella succinogenes.	the basal body of wolinella succinogenes consists of a central rod, a set of two rings (l and p rings), a basal disk from 70 to 200 nm in diameter, and a terminal knob. in negatively stained preparations of flagellar hook-basal body complexes, some disks remain fixed perpendicularly to the grid and show that such a disk is located on the distal side of the p ring. the basal disks have been isolated with and without the p ring; in both cases there is a hole in the center of the disk. the diameter ...	1992	1370283
myeloid and erythroid progenitor cells from normal bone marrow adhere to collagen type i.	one of the mechanisms by which normal hematopoietic progenitor cells remain localized within the bone marrow microenvironment is likely to involve adhesion of these cells to extracellular matrix (ecm) proteins. for example, there is evidence that uncommitted, hla-dr-negative progenitor cells and committed erythroid precursors (bfu-e) bind to fibronectin. however, fibronectin is not known to mediate binding of committed myeloid (granulocyte-macrophage) progenitors, raising the possibility that ot ...	2004	1370640
ion channel selectivity, permeation, and block.		2006	1382215
design a clinical information system.		2006	1392927
improving the preregistration period.		2006	1393214
study of acute intraoperative suprachoroidal hemorrhage.	acute intraoperative suprachoroidal hemorrhage or effusion (aish) was studied in a prospective manner over the past three years. in a general cataract surgery population of 2,523 patient eyes, 15 (0.6%) experienced an aish. results of a specific surgical management technique are presented. surgical control of the aish consisted of immediate closure of the incision and application of pressure directly to the eye. this tamponades the effusion or hemorrhage, which allows coagulation and completion ...	2006	1403754
isolation and sequence of a cdna encoding the precursor of a bombesinlike peptide from brain and early embryos of xenopus laevis.	a cdna encoding the precursor of a bombesinlike peptide was isolated from brain of xenopus laevis. the predicted end product resembles neuromedin b, which was originally isolated from mammalian spinal cord. the mrna for this precursor was also present in gastrointestinal tract and in ovaries. moreover, it could be detected in early embryos (stage 2 and stage 10) of x. laevis. these findings suggest novel roles for peptides of the bombesin family in oocyte maturation and early amphibian developme ...	1992	1409705
relative effects of intraoperative tissue expansion and undermining on wound closing tensions.	intraoperative tissue expansion is advocated as a technique to facilitate closure of soft-tissue wounds with less tension than if they were closed primarily without expansion or, presumably, simple undermining. few objective studies have been done, however, to validate the technique. we specifically questioned the relative effects of intraoperative tissue expansion and undermining on wound closing tensions in an animal model. our data showed statistically significant reduction in the force requi ...	1992	1418898
targeted cytokine production.	it has been well established that bispecific antibodies containing anti-t-cell receptor mabs crosslinked to anti-tumor mabs induce t cells to lyse tumor cells, as measured in a 51cr-release assay. such lysis requires direct attachment between target and cytotoxic cells and most probably involves the exocytosis of cytolytic substances into the cell:cell interface. in addition, targeted t cells mediate a second activity, the secretion into the medium of factors that can block the growth of bound t ...	1992	1428400
sexual cranial dimorphism in malnourished rats treated with growth hormone.	one hundred and sixty two holtzman rats of both sexes were malnourished during suckling and post-weaning periods. some of them received periodic injections of growth hormone. after sampling, at 56 days of age, skulls were cleaned and measured. differences within and between sexes were estimated by mahalanobis d2 distances. normal cranial differentiation between sexes (scd) was decreased by malnutrition and restored by growth hormone treatment. the effect of the growth hormone on skull size was l ...	1992	1428418
"raynaud's disease" in migraineurs: one entity or two?	two cases are reported of patients who were diagnosed as having both migraine and raynaud's disease. because they were able to achieve effective control of both headaches and extremity temperature after undergoing a comprehensive approach--utilizing medication, biofeedback, and psychotherapy--it is suggested that both conditions are manifestations of the same disorder. it is recommended that a first step in approaching concurrent diagnoses of this type involve combined treatment as is often used ...	2006	1446993
education in radiation oncology in europe.	the outcome of an inventory among 22 european countries with respect to the radiotherapy facilities and the training of new radiation oncologists in each country is described. the radiotherapeutic profession, which mostly prescribes also cytostatics or hormones, has become well-regulated in the last 20 years. most radiation oncologists are also involved in the diagnostic work-up and follow-up of the cancer patient. the numbers of radiotherapists and other staff, treatment capacities, and patient ...	2006	1447008
[colchicine in toxic liver cirrhosis and primary biliary cirrhosis].	in animals, colchicine has been shown hepatoprotective, which is related to its anti-fibrotic and anti-inflammatory effect. in man, colchicine has been used for the treatment of alcoholic liver disease and primary biliary cirrhosis. although controlled trials observed an improvement of liver function tests under colchicine, the survival rate in most studies was only slightly improved without reaching statistical significance. therefore, at present, no final evaluation of colchicine for the treat ...	1992	1449015
angiokeratoma of the clitoris: a subtype of angiokeratoma vulvae.	a 24-year-old married woman had an angiokeratoma of the vulva measuring 3 x 3 x 4 mm localized at the clitoris. the nodule was noticed when she was pregnant with her first child. this tumor grew with occasional tenderness and bleeding during pregnancy, but its size did not change after delivery. the growth of this tumor might be attributable to an increase in venous pressure or serum progesterone levels; therefore this disorder might be classified as a subtype of angiokeratoma of the vulva. this ...	2006	1479114
volumes of the cytoarchitectonic areas in the rat cerebral cortex.	the volumes of the isocortical, periallocortical and allocortical areas were measured in the brains of nine 6 month old male wistar rats. after perfusion fixation with bodian's solution, determination of brain weight, paraffin embedding and serial sectioning, the areal volumes were estimated with the cavalieri method and corrected for individual brain shrinkage. thus, fresh volumes were measured. the present report provides comprehensive data on the volumes of the cortical areas of one hemispher ...	1992	1479193
sleep organization and energy expenditure of breast-fed and formula-fed infants.	sleep organization of infants may be influenced by differences in nutrient intakes from human milk and formula. because sleep/awake and sleep stage patterns affect energy expenditure, we hypothesized that differences in sleep organization between breast-fed and formula-fed infants might account in part for differences in energy expenditure between feeding groups. sleep stages and cycling of 4-mo-old breast-fed (n = 10) formula-fed (n = 10) infants were studied with simultaneous measurements of e ...	1992	1480450
a protocol system to satisfy research specific, disease specific, physician specific, and patient specific informational needs.	the department of medicine at loyola university medical center chicago (lumc) has developed and is utilizing a patient information protocol system (pips) to address clinical and research informational needs. pips, an integrated module of the department's patient information management system (pims), enables end-users to access pre-defined informational templates or "protocols". protocols detail pre-defined data requirements for patient management or clinical research needs. each protocol consist ...	2006	1482966
anterior chamber lens exchange.		2006	1489454
[insufficient treatment because of special payment. interview by bjørn arild ostby].		2006	1489614
use of the polymerase chain reaction to isolate an s-locus glycoprotein cdna introgressed from brassica campestris into b. napus ssp. oleifera.	a self-incompatible canola-quality brassica napus ssp. oleifera line (w1) was generated by introgressing the s-locus from a self-incompatible b. campestris plant into the westar cultivar. using the polymerase chain reaction (pcr) with primers derived from conserved regions in s-locus glycoprotein (slg) alleles, the central region of the active slg gene (910) was obtained. the remaining portions of the cdna for this 910 gene were subsequently cloned using the pcr-rapid amplification of cdna ends ...	2006	1508146
an apparently allosteric effect involving n2o with the nitrous oxide reductase from wolinella succinogenes.	it was shown that kcat for the benzyl viologen cation (bv+)-n2o oxidoreductase activity of nitrous oxide reductase from wolinella succinogenes was 2-3 times greater at high n2o concentrations than at low. this effect of n2o on kcat exhibited a titration curve implicating a single secondary binding site for n2o with a kd of 130-200 microm (km with respect to n2o is about 2.5 microm). this work represents the first evidence of an apparently allosteric kinetic effect among nitrous oxide reductases. ...	1992	1520293
the influence of the stomach on crop function and feeding behavior in domestic turkeys.	we tested the hypotheses that motility of the crop and muscular stomach are coordinated and that the stomach exerts primary control over crop filling and emptying in domestic turkeys. simultaneous recordings of motility of the crop, esophagus, and stomach with implanted strain gauge transducers and visual observations of food passage using image intensification radiography revealed an inverse relationship between the frequency of stomach and crop contractions. artificially filling the stomach of ...	1992	1523251
carbohydrate specificity of the receptor sites of mistletoe toxic lectin-i.	the carbohydrate specificity of mistletoe toxic lectin-i (ml-i) was studied by haemagglutination-inhibition assay. the results indicated that ml-i has a broad range of affinity for gal alpha,beta linked sequences. the galabiose (e, gal alpha 1----4gal) sequence, a receptor of the uropathogenic e. coli ligand, was one of the best disaccharide inhibitors tested. the lectin also exhibits affinity for lac(gal beta 1----4glc), t(gal beta 1----3galnac), i/ii(gal beta 1----3/4glcnac) and b(gal alpha 1- ...	2006	1525184
effects of fluorescein isothiocyanate on insulin actions in rat adipocytes.	the effects of fluorescein isothiocyanate ii (fitc) on the actions of insulin in rat adipocytes were studied. when adipocytes were incubated with fitc at ph 7.4 (2 mm agent, 8 min), the cells were completely deprived of their specific insulin-binding activity and rendered unresponsive to the hormone. the effect of fitc on the insulin-binding activity was milder at ph 9.0, and camp phosphodiesterase in cells exposed to fitc at ph 9.0 was maximally stimulated if the insulin concentration was incre ...	1992	1536560
interaction of aminoalkylcarbamates of forskolin with adenylyl cyclase: synthesis of an iodinated derivative of forskolin with high affinity for adenylyl cyclase.	7-(2-aminoethyl)aminocarbonyl-7-desacetylforskolin (7-aec-fsk) and 6-(2-aminoethyl)aminocarbonylforskolin (6-aec-fsk) were synthesized and tested for their ability to activate adenylyl cyclase and inhibit the high affinity binding of [3h]forskolin to bovine brain membranes. forskolin and 7-aec-fsk were equipotent in activating adenylyl cyclase, with ec50 values of about 4 microm, whereas 6-aec-fsk had an ec50 of about 2 microm. 6-aec-fsk and 7-aec-fsk stimulated adenylyl cyclase about 7-fold ove ...	1992	1538712
sucralfate.		2006	1538733
case report: myocardial ischemia: an overlooked substrate in syncope of aortic stenosis.	the cause of the syncope in aortic stenosis has been the subject of controversy partly because only a few patients have been monitored during their syncopal episodes. among the mechanisms proposed are hypersensitive carotid sinus, complete a-v block, ventricular arrhythmias, and ischemic myocardial depression. it is now accepted that the syncope is caused by a vasodepressor response from stimulation of left ventricular baroceptors, resulting in reflex hypotension and bradycardia. this case repor ...	2006	1539605
osteoporosis: whose problem is it?		2006	1540021
regular processor control improves portal film quality.		2006	1557499
localization and quantification of nonapeptide binding sites in the kidney of xenopus laevis: evidence for the existence of two different nonapeptide receptors.	the distribution and properties of nonapeptide binding sites in the kidney of the anuran xenopus laevis were investigated using quantitative in vitro autoradiography. the binding studies were performed with [3h]arginine vasopressin (avp) as ligand because [125i]arginine vasotocin (avt) lacks biological activity. specific binding sites for [3h]avp are located in the glomeruli of the kidney. [3h]avp binding results in a steady state of association and dissociation between ligand and binding sites. ...	1992	1563620
ab-interno neodymium:yag versus erbium:yag laser sclerostomies in a rabbit model.	this study was undertaken to determine whether thermally-induced tissue necrosis was a factor in ab-interno contact-laser sclerostomy failure. a rabbit model was used to compare the continuous-wave neodymium (nd):yag with the pulsed erbium (er):yag laser with respect to such failure. laser energy was focused into a fused-silica fiber optic (400 microns) for the nd:yag laser (12 w; 3 to 5 seconds), and into a single-crystal, uncladded sapphire fiber optic (250 microns) for the er:yag laser (7 to ...	1992	1574289
[treatment of stress urinary incontinence in women, by the raz technique. results].	the results achieved with the raz technique in 65 patients with stress urinary incontinence are presented. of these, 23 (35.4%) had mixed incontinence. overall, good results were achieved in 83.1%, defined as correction of incontinence and no micturition disorder. the present study emphasizes the importance of correct diagnosis for surgical indication. this technique is indicated for mixed urinary incontinence and coexisting cystocele or after previous failed antiincontinence surgery.	2006	1586218
the quinone-reactive ni/fe-hydrogenase of wolinella succinogenes.	the hydrogenase (hyd) isolated from the cytoplasmic membrane of wolinella succinogenes consists of three polypeptides (hyda, hydb and hydc) and contains cytochrome b (6.4 mumol/g protein), which was reduced upon the addition of h2. the enzyme catalyzed the reduction of 2,3-dimethyl-1,4-naphthoquinone with h2, in contrast to an earlier preparation which was made up of hyda and hydb only and did not contain cytochrome b (unden, g., böcher, r., knecht, j. & kröger, a. (1982) febs lett. 145, 230-234 ...	1992	1587288
ossification of the posterior cervical longitudinal ligament.	forty patients with cervical myelopathy due to opll (ossification of the posterior longitudinal ligament) of the cervical spine were studied. according to abe's or yamamoto's classification, 12 of them had a 50% decrease in the cross-sectional area of the spinal canal. subtotal vertebrectomy was carried out in 8 of these patients and the remaining 4 patients received posterior decompression. we concluded that anterior decompression, if possible, is the treatment of choice and posterior decompres ...	2006	1595391
late onset familial hallervorden-spatz disease: mr findings in two sisters.	two sisters affected by late onset hallervorden-spatz disease are described. in both patients, mr showed rings of decreased signal intensity surrounding hyperintense areas that gave a target-like appearance to the globi pallidi, a finding that corresponds with the known pathologic lesions in the disease. mr reflects the metabolic and anatomic evaluation of this disease.	2006	1595483
cloning and nucleotide sequence of the psra gene of wolinella succinogenes polysulphide reductase.	the polysulphide reductase (formerly sulphur reductase) of wolinella succinogenes is a component of the phosphorylative electron transport system with polysulphide as the terminal acceptor. using an antiserum raised against the major subunit (psra, 85 kda) of the enzyme, the corresponding gene (psra) was cloned from a lambda-gene bank. the n-terminal amino acid sequence of psra mapped within the psra gene product, which also contained an apparent signal peptide. downstream of the psra gene two m ...	1992	1597189
the relation of ligand binding to redox state in the hexa-heme nitrite reductase of wolinella succinogenes.	ligand binding reactions and the relation between redox state and ligand binding in the hexa-heme nitrite reductase of wolinella succinogenes have been studied using laser flash photolysis. on a picosecond time scale, a rapid excursion was observed corresponding to the breaking and reforming of an iron histidine bond. with the co derivative, a geminate reaction was observed with a rate of 3 ns-1. on a nanosecond time scale, no slower geminate reactions were observed. for the cyanide derivative, ...	1992	1597437
changes in auditory brainstem response in rats chronically exposed to carbon disulfide.	the chronic effect of carbon disulfide (cs2) on the central nervous system (cns) was studied by examining auditory brainstem responses (abrs) in female rats (jcl wistar) exposed to 200 ppm or 800 ppm cs2 by inhalation, 6 h a day, 5 days a week, for 15 weeks. two modes of abrs evoked by clicks at 61 and 96 db sound pressure levels (61 db-abr and 96 db-abr) were recorded during the exposure and for 6 weeks afterwards. three main components (i, iii and v) of abrs were analyzed from the latencies an ...	1992	1610296
[possibilities and limitations of a nursing department. nursing and politics].		2006	1618101
[fundus plication with or without proximal selective vagotomy?].	the aim of this study was to determine the influence of proximal gastric vagotomy on the outcome after fundoplication. of 141 patients operated on for reflux disease between 1972 and 1988, 53 had fundoplication alone (group a) and 88 fundoplication combined with proximal gastric vagotomy (group b). the two groups were similar with regard to the severity of the reflux disease (esophagitis: a 69%, b 73%) but had a different incidence of concomitant ulcer disease (a 2%, b 55%). after a mean follow- ...	2006	1621082
[the human chorionic gonadotropin (hcg) receptor: a new class within the family of gtp protein coupled receptors. epitope mapping of receptor-bound agonistic and antagonistic forms of hcg].	human chorionic gonadotropin (hcg) is a member of the glycoprotein hormone family. it is composed of an alpha and a beta subunit, the latter being closely homologous to that of human luteinizing hormone (hlh). hcg and hlh bind to the same receptor. the molecular mass of hcg is 38 kd, up to 30% of which is contributed by the carbohydrate moieties linked to each of the two subunits. structure-function relationship studies have indicated that both subunits interact with the receptor and that altoge ...	1992	1636261
reactivity of the bacillus subtilis succinate dehydrogenase complex with quinones.	the succinate dehydrogenase isolated from bacillus subtilis was found to catalyze the oxidation of succinate with hydrophilic quinones. either naphthoquinones or benzoquinones served as acceptors. the enzyme activity increased with the redox potential of the quinone. the highest turnover number was commensurate with that of the bacterial succinate respiration in vivo. the succinate dehydrogenase was similarly active in fumarate reduction with quinols. the highest activity was obtained with the m ...	1991	1655027
terminal epidermal differentiation of human keratinocytes grown in chemically defined medium on inert filter substrates at the air-liquid interface.	a fully differentiated epithelium having the features of epidermis was obtained in vitro by culturing second-passage normal human keratinocytes (nhk) in the chemically defined medium mcdb 153 on inert filter substrates at the air-liquid interface for 14 d. vertical sections stained for histology and indirect immunofluorescence studies show a correct stratification and expression of differentiation markers. the presence of desmosomes, keratohyalin granules, and lamellar granules, and the formatio ...	1990	1698886
phylogeny of helicobacter felis sp. nov., helicobacter mustelae, and related bacteria.	strain cs1t (t = type strain) is a gram-negative, microaerophilic, urease-positive, spiral-shaped bacterium that was isolated from the gastric mucosa of a cat. additional strains which possessed biochemical and ultrastructural characteristics similar to those of strain cs1t were isolated from the gastric mucosa of cats and dogs. the guanine-plus-cytosine content of the dna of strain cs1t was 42.5 mol%. the 16s rrna sequences of strain cs1t, strain ds3 (a spiral-shaped isolate from a dog), and he ...	1991	1704791
revision of campylobacter, helicobacter, and wolinella taxonomy: emendation of generic descriptions and proposal of arcobacter gen. nov.	hybridization experiments were carried out between dnas from more than 70 strains of campylobacter spp. and related taxa and either 3h-labeled 23s rrnas from reference strains belonging to campylobacter fetus, campylobacter concisus, campylobacter sputorum, campylobacter coli, and campylobacter nitrofigilis, an unnamed campylobacter sp. strain, and a wolinella succinogenes strain or 3h- or 14c-labeled 23s rrnas from 13 gram-negative reference strains. an immunotyping analysis of 130 antigens ver ...	1991	1704793
atypical structure of the 23s ribosomal rna molecule in certain oral bacteria.	ribosomal rna (rrna) isolated from wolinella recta and seven related bacteria was examined by agarose gel electrophoresis. the 23s rrna molecule could not be detected in w. recta, wolinella curva, bacteroides gracilis, or bacteroides ureolyticus. in place of the 23s molecule, there were three smaller molecules of approximately 1700, 650, and 600 bases designated 23s alpha, 23s beta, and 23s delta, respectively. an intact 23s rrna molecule could be isolated from wolinella succinogenes, campylobac ...	1991	1710629
direct polymerase chain reaction test for detection of helicobacter pylori in humans and animals.	we designed a polymerase chain reaction (pcr) for amplifying the helicobacter pylori gene encoding 16s rrna. primers for the specific detection of h. pylori were designed for areas of the 16s rrna gene in which there is the least sequence homology between h. pylori and its closest relatives. the specificity of detection was confirmed by ensuring that the primers did not amplify dna extracts from the campylobacters h. cinaedi, h. mustelae, and wolinella succinogenes, which are the closest relativ ...	1991	1723072
helicobacter muridarum sp. nov., a microaerophilic helical bacterium with a novel ultrastructure isolated from the intestinal mucosa of rodents.	helical organisms with novel ultrastructural characteristics were isolated from the intestinal mucosa of rats and mice. these bacteria were characterized by the presence of 9 to 11 periplasmic fibers which appeared as concentric helical ridges on the surface of each cell. the cells were motile with a rapid corkscrewlike motion and had bipolar tufts of 10 to 14 sheathed flagella. the bacteria were microaerophilic, nutritionally fastidious, and physiologically similar to helicobacter species and w ...	1992	1736969
acute myocardial infarction after blunt chest trauma in young people: need for prompt intervention.	we describe four cases of acute myocardial infarction in young patients, secondary to blunt chest trauma. one case was treated with intracoronary thrombolysis and angioplasty, two cases received systemic thrombolysis, and the last one did not have any reperfusion therapy. the coronary angiograms of the left anterior descending artery showed thrombosis in two cases, coronary dissection in one case, and no morphological lesions in the other. we encourage the early performance of angiographic studi ...	2006	1764738
analysis of high psa n-cam expression during mammalian spinal cord and peripheral nervous system development.	using a monoclonal antibody that recognizes specifically a high polysialylated form of n-cam (high psa n-cam), the temporal and spatial expression of this molecule was studied in developing spinal cord and neural crest derivatives of mouse truncal region. temporal expression was analyzed on immunoblots of spinal cord and dorsal root ganglia (drgs) extracts microdissected at different developmental stages. analysis of the ratio of high psa n-cam to total n-cam indicated that sialylation and desia ...	1991	1769342
[clinico-morphological signs of different forms of destructive pancreatitis].	clinicomorphological comparisons in 434 cases of destructive pancreatitis showed that macroscopic signs of destruction develop in the first 12 hours from the onset of the attack. the elaborated criteria make it possible to evaluate the main morphological components of destructive pancreatitis--pancreonecrosis proper, parapancreatitis, peritonitis, and "polyvisceritis" and to use therapeutic measures on an individual basis.	2006	1779556
c2 rotation and spinous process deviation in migraine: cause or effect or coincidence?	previous reports have shown an association between the side of c2 spinous process deviation or asymmetrical prominence, or vertebral rotation, and the side of the headache in unilateral migraine. however, this study has found that such c2 appearances were present as frequently in the controls as in the migraine patients, and that there was no association between the side of the anomaly and the lateralisation of the headache. the results were comparable for the different sub-groups of migraine.	2007	1780047
cloning and nucleotide sequence of the structural genes encoding the formate dehydrogenase of wolinella succinogenes.	the formate dehydrogenase of wolinella succinogenes is a membraneous molybdo-enzyme which is involved in phosphorylative electron transport. the gene (fdha) encoding the largest subunit was isolated from a gene bank by immunological screening. the fdha gene was located in an apparent transcriptional unit (fdha,b,c,d) together with three more structural genes. the n-terminal sequences of three polypeptides present in the isolated enzyme were found to map within the fdha, b and c structural genes. ...	1991	1781728
colorectal neoplasia: screening average risk individuals.		2006	1782367