Publications

acute bacterial meningitis at boston city hospital during 12 selected years, 1935-1972.	data are presented on the occurrence of and mortality rate from acute bacterial meningitis at boston city hospital during 12 years between 1935 and 1972 selected in relation to the introduction of potent antibacterial agents. the most frequent causative organisms were streptococcus pneumoniae, neisseria meningitidis, and haemophilus influenzae, but large proportions were caused by other gram-positive cocci and gram-negative bacilli. the greatest reduction in mortality rate after antibiotics beca ...	1977	20479
a new spectrophotometric assay for protein in cell extracts.		1977	20815
an nadp-linked acetoacetyl coa reductase from zoogloea ramigera.	zoogloea ramigera i-16 m was found to contain two stereospecific acetoacetyl coa reductases; one was nadp+-linked and d(-)-beta-hydroxybutyryl coa specific and the other was nad+-linked and l(+)-isomer specific. the nadp+-linked enzyme, purified approximately 150-fold, had a ph optimum for the reduction of acetoacetyl coa at 8.1, but no definite ph optimum for the oxidation for beta-hydroxybutyryl coa. the apparent michaelis constants for acetoacetyl coa and nadph were 8.3 and 21 micrometer, res ...	1977	20866
the reversible inhibition of gluconeogenesis in kidney cortex by diazenedicarboxylic acid bis (n,n-dimethylamide).		1977	21091
studies on the heterotropic interaction of hemoglobin. ii. role of beta-146 and beta-2 histidines in the alkaline bohr effect.		1998	21177
the structure and function of ribonuclease t1 xxiv. preparation and properties of a stable water-insoluble polyacrylamide derivative of ribonuclease t1.	ribonuclease t1 ec 3.1.4.8 was coupled to a water-insoluble cross-linked polyacrylamide (enzacryl ah) by the acid azide method. the immobilized enzyme exhibited about 45% and 77% of the original activity toward yeast rna and 2', 3-cyclic gmp, respectively, as substrates. although the specific activity was lowered by the coupling, the immobilized enzyme was found to be far more stable to heat and extremes of ph than the native enzyme. the immobilized enzyme was active toward rna even above ph 9 ( ...	1977	21179
properties of deoxynucleoside 5'-monophosphatase induced by bacteriophage t5 after infection of escherichia coli.	bacteriophage t5 induced a deoxynucleoside 5'-monophosphatase during its infection of escherichia coli. the enzyme was purified about 100-fold. it was clearly distinct from the host 5'-nucleotidase activity in its physical characteristics and substrate specificity. the enzyme was active on deoxynucleoside 5'-monophosphates but was not active as a phosphatase on ribonucleotides, deoxynucleoside 5'-triphosphates, deoxynucleoside 3'-monophosphates, or deoxyoligonucleotides. furthermore, it did not ...	1977	21305
early interactions of competent bacteria with nucleic acids (author's transl).		1977	21387
determination of 3-methoxy-4-hydroxyphenylglycol in urine and the effect of diet on its excretion.	a modified method is described for determination of 3-methoxy-4-hydroxyphenylglycol (mhpg) in urine by gas chromatography with electron capture detection. the method is reproducible and mean (+/- sd) recoveries of mhpg from urine were 78.5 +/- 12.7% and 76.5 +/- 15.0% in two separate series of analyses. mean 24-hour mhpg excretion was 1884 +/- 591 microgram in 11 normal subjects and 1688 +/- 593 microgram in 20 patients with various types of depression. males excreted more mhpg than females but ...	1998	21430
repeat myocardial revascularization for uncontrollable angina after occlusion of prior aortocoronary bypass.	twelve patients at emory university hospital have had repeat myocardial revascularization for recurrent, uncontrollable, disabling angina pectoris after previous coronary artery bypass grafts. the interval betweeen initial bypass procedure and reoperation ranged from six weeks to six years. the native coronary circulation remained unchanged in six, had developed additional proximal (left main) obstruction in four, and had advanced stenosis at the site of former anastomosis in three. repeat revas ...	1998	21455
[pathogenesis of anemias in systemic diseases of the connective tissue].		1998	21487
[surgical technic in pseudarthrosis of the scaphoid bone].		1997	21589
effect of pindolol on experimental hypertension in the dog. comparison with propranolol, practolol, oxprenolol, bupranolol, alprenolol and butoxamine.		1977	21636
interaction of folic acid with ribonuclease a.		1977	21693
liver enzyme adaptation after lithium administration in handled and nonhandled rats.	we have examined the interaction of lithium administration and the infant stimulation procedure of handling on hormonally regulated enzymes of liver. animals handled in infancy show an increased morning corticosterone level in response to lithium feeding and markedly elevated serum glucose during refeeding following a two day fast, when compared to non-handled control animals. lithium alters serum corticosterone both in response to the stress of fasting, and during the diurnal cycle following gl ...	1977	21840
studies on phosphate-solubilizing bacteria in soil and rhizosphere of different plants. ii. selection of the most efficient phosphate-dissolvers and their morphological grouping.	two hundred colonies which showed positive reaction on the plates prepared for the phosphate-dissolving bacteria from control soil rhizosphere soils and rhizoplane samples of maize, peas, or cotton were isolated at random. fifty isolates were selected as the most efficient isolates according to their capability for increasing the amounts of available phosphorus in the media with corresponding decreases in ph values. the percentage of the most efficient isolates differed according to type of plan ...	1999	22210
comparison of the ribonucleoproteins of different rabies virus serotypes by radioimmunoassay.	radioimmunoassay (ria) provides a sensitive serological procedure for detecting rabies virus ribonucleoprotein (rnp) as well as its specific antibodies, ria was carried out using highly purified rnps labelled by the chloramine-t method. this paper describes optimal conditions for iodination of rnp with high specific activity. the optimal concentrations of 125i, rnp, chloramine-t, and reducing agent as well as the effect of ph on the reaction were investigated. ria proved to be extremely sensitiv ...	1977	22569
aerobic and anaerobic bacteriology of acute otitis media in children.	tympanocentesis and aerobic and anaerobic cultivation of the middle-ear fluid obtained was performed through one or both tympanic membranes of 62 children with acute otitis media. aerobic bacteria alone, predominantely pneumococcus and hemophilus influenzae, were isolated from 57% of patients; anaerobic organisms alone, most commonly propionibacterium acnes and peptococcus, from 15%. thirteen percent yielded mixtures of aerobes and anaerobes, and several had multiple aerobic or anaerobic agents. ...	1978	22590
central antagonism of tyramine-induced systemic hypotension by mescaline.		1977	22607
an automated immunoprecipitin assay of prothrombin for the control of anti-coagulant therapy [proceedings].		1998	22662
the increasing incidence of ampicillin-resistant haemophilus influenzae. a cause of otitis media.	middle ear exudate was obtained by myringotomy or aspiration from 625 suburban children, aged 1 month to 12 years, who had acute otitis media; bacterial pathogens were isolated from 71%. haemophilus species were isolated from 212 (29%), and streptococcus pneumoniae from 205 (28%). from 1975 to august 1977, the number of haemophilus isolates found to be resistant to ampicillin has appreciably increased. currently, 8% of all cases of acute otitis media in the washington, dc, area are due to h infl ...	1978	22767
effect of h+ on spontaneous neuronal activity in the surface layer of the rat medulla oblongata in vitro.	the effect of changing extracellular ph (phe) on the spontaneous activity of neurons in brain slices taken from the ventral layer of the rat medulla oblongata was compared to the response of neurons in dorsal slices. in the ventral medulla, more than 50% of the neurons were excited by h+. these neurons were found just lateral to the pyramidal tract between the root of the hypoglossal nerve and the trapezoid body. in the dorsal medulla, low phe caused an inhibition of activity in most neurons, al ...	1977	22840
non-specific pharmacodynamic action of a piperidyl derivative (thioridazinum) of phenothiazine on the reactivity of the genital tract.		1977	22884
[significance of anti-albumin antibodies in chronic liver disease].		1999	22919
an in vivo and in vitro analysis of the alloantigen response in syrian hamsters.		1977	22946
experimental liver failure. a comparison between hepatectomy and hepatic devascularization in the pig.	difficulties in the treatment of acute hepatic failure due to insufficient knowledge of the pathogenesis and the impredectability of the course has made an experimental model desirable. a number of such models have been proposed, among these hepatectomy and total hepatic devascularization. in the present study hepatectomy and total hepatic devascularization have been compared, as it has been doubted if hepatectomy, not including necrotic liver tissue, is a valid model of human hepatic failure. n ...	1977	22974
response of lipogenic enzymes to overfeeding in liver and adipose tissue of light and heavy breeds of chicks.		1978	23141
recent epidemiological features on korean haemorrhagic fever in the republic of korea.		1997	23359
comparative digestibility of acid detergent fiber by laboratory albino and wild polynesian rats.	the effects of adding 5%, 10%, and 15% acid detergent fiber to a nonfibrous basal diet were examined in a comparative feeding study with polynesian rats (rattus exulans) and laboratory rats. digestibility coefficients for dry matter, crude protein, and gross energy declined significantly in both species as fiber content increased, but averaged significantly lower in the polynesian than in the laboratory rat. fiber digestibility was not significantly affected by fiber level but was by species, wi ...	1978	23419
physicochemical properties of glycyrrhizic acid in aqueous media ii: effect on flocculation-deflocculation behavior of suspensions of sulfathiazole and graphite.	the flocculation-deflocculation behavior of sulfathiazole and graphite in aqueous solutions of glycyrrhizic acid was studied by measuring the sedimentation volume and turbidity of supernates. the dispersing effect of glycyrrhizic acid on suspension of sulfathiazole showed a maximum in the ph 3-4 region, the same ph region where the zeta-potential of sulfathiazole particles showed a negative maximum. the results were explained by the variation of degrees of ionization of glycyrrhizic acid and sul ...	1997	23423
meningitis: the influence of routine otolaryngologic consultation on morbidity and mortality in 290 cases.	a prospective study was designed to obtain data on all meningitis patients admitted to a large county communicable disease unit. the epidemiologic and clinical features of 290 cases were analyzed to ascertain the effect of routine o.r.l. consultation on the morbidity and mortality of this disease. the results of physical examination provided current statistics as to the existence of ear, nose, and throat diseases associated with meningitis.	1978	23470
do bacteria mutate to erythromycin resistance?		1977	23582
gamma-radiolyses of dna in oxygenated aqueous solution. structure of an alkali-labile site.	erythritol-1-d1 has been isolated from gamma-irradiated aqueous oxygenated solution of dna after reductions with nabd4, alkali and phosphatase treatment. it is concluded that this product stems from a d-erythrose 2,4-diphosphate unit in the dna which is formed via a sequence of reactions following h-abstraction at c-2' by oh radicals.	1998	23616
[detection of female heterozygous glucose-6-phosphate dehydrogenase deficiency].	diagnostics of heterozygotes are required for population studies, for the detection and consultation of persons with g-6-pd deficiency prone to hemolysis. the diagnostics of heterozygous females with the corresponding trait are problematic in families without hemizygous patients. 1. the determination of the activity is only applicable to the differentiation between heterozygotes and homozygotes if the activities are below the reference range. heterozygous g-6-pd deficiency with normal activity c ...	1998	23637
activities of leishmania from human skin ulcers in small laboratory animals.		1977	23653
an adenosine 3':5'-monophosphate-adenosine binding protein from mouse liver. factors affecting the activation of the binding protein by adenosine 5'-triphosphate.		1978	23726
effects of bromocriptine on adenylate cyclase and phosphodiesterase activities of rat striatum.	the activity of 2-bromo-alpha-ergokryptine (bromocriptine) (5 mg kg-1, i.p.) on adenylate cyclase and on phosphodiesterase (pde-pde ii) of rat striatum, has been examined both in vitro and in vivo. in vitro and in vivo bromocriptine stimulated adenylate cyclase activity, but reduced the stimulating effect of dopamine on adenylate cyclase activity. bromocriptine showed a dose-dependent biphasic action on phosphodiesterases in vitro while in vivo it stimulated them. the results obtained proved bro ...	1978	24111
effects of stimulants, anorectics, and related drugs on schedule-controlled behavior.		1978	24228
dissolution and uptake of cadmium from dental gold solder alloy implants.	pure metallic cadmium was irradiated by means of thermal neutrons. the irradiated cadmium (115cd) was placed in bags of gold foil and the bags were implanted subcutaneously in the neck region of mice. two and 3d respectively after implantation the mice were killed, the bags removed and the animals subjected to whole-body autoradiography. the autoradiograms revealed an uptake of 115cd in liver and kidney. in another experiment specimens of a cadmium-containing dental gold solder alloy, a cadmium- ...	1997	24262
pharmacists' knowledge and attitudes regarding monitoring the behaviors of children with learning disabilities.	the attitudes and knowledge of pharmacists in nebraska regarding children's learning disabilities were surveyed by questionnaire. one hundred thirty-three pharmacists responded. the results were analyzed according to type of practice (community, chain and hospital) and age (20--30 years, 31--40 years, 41--50 years, and 51 years and over). the results indicate that pharmacists are being asked about learning disabilities. overall, 53% of the pharmacists responding had been asked about learning dis ...	1998	24339
active groups of extracellular endo-d-galacturonanase of aspergillus niger derived from ph effect on kinetic data.	in an attempt to characterize the groups essential for the catalytic action extracellular endo-d-galacturonanase of aspergillus niger (poly (1,4-alpha-d-galacturonide) glycanohydrolase, ec 3.2.1.15) the behaviour of the kinetic parameters as a function of ph was examined. the dependence of kcat and kcat/km on ph suggests that two dissociable groups are involved, for which the pk values of about 3.0 and 5.0 in the free enzyme and 3.06 and 5.72 in the catalytic complex were found at 30 degrees c. ...	1978	24473
neurogenic vasodilation of cat cerebral arteries.	transmural nerve stimulation (tns) with 0.3-msec pulses between 1 and 25 hz dilated cat cerebral artery segments in the presence of active muscle tone. maximum vasodilatation occurred at 8 hz. the dilator response to exogenous acetylcholine, but not to tns, was abolished by atropine. neither physostigmine nor hemicholinium affected the dilator response to tns, which persisted after administration of guanethidine, phenoxybenzamine, propranolol, reserpine, and chronic sympathectomy. however, it wa ...	1978	24505
the use of gvh methods in analysis of the b-complex.		1977	24559
[azathioprine in long-term therapy of inflammatory rheumatic diseases. variability of laboratory chemical parameters].		1999	24794
inhibition of growth and guanylate cyclase activity of an undifferentiated prostate adenocarcinoma by an extract of the balsam pear (momordica charantia abbreviata).	we have recently described the presence of a guanylate cyclase gtp pyrophosphate-lyase (cyclizing), ec 4.6.1.2 inhibitor (gci) in an aqueous extract of the balsam pear (momordica charantia abbreviata). because the guanylate cyclase-cyclic gmp system is though to be involved in cell growth, dna and rna synthesis, and possible malignant transformation, we examined the effect of the aqueous extract containing gci on an undifferentiated adenocarcinoma of the rat prostate and concanavalin-a-stimulate ...	1978	24847
[acid-base equilibrium in patients with tick-borne encephalitis and similar diseases].	the study is concerned with the acid-base balance in 92 patients with tick-borne encephalitis, tick-borne fever and meningitis of an obscure etiology. in many cases there was a shift in the direction of a metabolic acidosis, which was most vividly expressed in the meningitic form of tick-borne encephalitis. some of the patients were treated by sodium bicarbonate which exerted a positive effect. the degree of changed indices of the acid-base balance and the time of their appearance helps in the d ...	1998	24968
[antidepressive agents are turning more practical].		1999	25383
exacerbations of chronic bronchitis: exogenous or endogenous infection?	six male patients with chronic bronchitis, who were known previously to have excreted streptococcus pneumoniae and/or haemophilus influenzae, both at the times of exacerbations and during remission, were studied for 43 to 52 months. sputum was examined fortnightly and at the time of exacerbations. strains of strep. pneumoniae were serotyped and those of haemophilus species were typed by antibiograms along with other supporting methods. sera collected before or at the time of an exacerbation and ...	1978	25664
rapid assays of urinary estriol in pregnant women.	two devices designed for rapid assay of urinary estriol, the e3 kit and e3 hair kit, were evaluated using urine samples taken from pregnant women. additionally, the clinical application of these devices in pregnancy management was examined. correlations were high between an established method and the e3 kit method (r = 0.819, p less than 0.001) and between the e3 hair kit method and the e3 kit method ( r = 0.936, p less than 0.01). e3 hair kit assays showing e3 values of less than 20 microgram/m ...	2000	25799
bacteriological findings in the transtracheal aspirate from patients with acute exacerbation of chronic bronchitis.	transtracheal aspirates from 87 patients with acute exacerbations of chronic bronchitis who had received no recent antibiotic treatment were examined. a single bacterial species was found in 83% of positive cultures. predominant pathogens were haemophilus influenzae and streptococcus pneumoniae which occurred jointly or separately in 50% of positive cultures. bacteria traditionally considered as non-pathogenic for the lower respiratory tract also appeared to play an aetiological role. enterobact ...	1978	25845
the detection of bacterial antigens by counter-immunoelectrophoresis in n. meningitidis, h. influenzae serotype b, s. pneumoniae infections. diagnostic value and evolutive aspect (in 216 cases) (author's transl).	using counterimmunoelectrophoresis (cie) the authors have assayed for soluble bacterial s. pneumoniae, n meningitidis group a, b, c. h. influenzae type b antigens, biological fluids in 216 patients (meningitis: 136; pneumonia: 76; miscellaneous: 4) during 16 months. because of heterogeneous recruiting (the bacteriology was carried out by different laboratories) the increase in aetiological diagnosis given by cie is only statistically valid for the bacteriologic negative group when blind antibiot ...	1977	26041
comparative experimental studies in animals and humans on gastrointestinal blood loss following antirheumatic pharmacotherapy (author's transl).	the gastrointestinal blood loss caused by the two antirheumatic drugs acetyl salicylic acid (asa) and 4-acetamidophenyl-2-acetoxybenzoate (benorilate, benortan) was compared in experimental animals and humans by measuring the total body iron retention. in wistar rats and humans the results indicate that the daily iron loss under asa is significantly higher (almost by the factor 2) than that under benorilate.	1978	26360
antibiotic resistance in streptococcus pneumoniae and haemophilus influenzae. report of a study group on bacterial resistance.	twenty laboratories in england and scotland took part in 1977 in a survey of antibiotic resistance in streptococcus pneumoniae and haemophilus influenzae. in str pneumoniae 59 (6.8%) of the 866 strains studied were resistant to tetracycline and three to chloramphenicol, and one strain showed a decreased susceptibility to penicillin. the prevalence of resistance to tetracycline was lower than that found in a similar study performed in 1975. nine hundred and fifty-two strains of h influenzae were ...	1978	26450
the metabolism of (2-cyclopentyl-6,7-dichloro-2-methyl-1-oxo-5-indanyloxy)acetic acid in chimpanzee and man.	the metabolism of the polyvalent saluretic agent (2-cyclopentyl-6,7-dichloro-2-methyl-1-oxo-5-indanyloxy)acetic acid was studied in chimpanzee and man. the drug was well absorbed and extensively metabolized by man. peak levels of drug (5--8 microgram/ml) occurred within 1.5--4.5 hr of drug administration. the plasma half-life was estimated to be 2 hr; a similar half-life was observed in the chimpanzee. little unchanged drug (less than 10%) was excreted in the urine of either species. similar met ...	1978	26552
acid release at meiotic maturation of oocytes in the polychaete annelid sabellaria alveolata.	about 1 pmole of acid per egg is released when prophasic oocytes undergo maturation under the action of sperm, proteases or ionophore a 23187. no similar acid release occurs at fertilization of matured oocytes. these findings are compared with data on urechis and sea urchin.	2001	26587
effect of amisyl and spasmolytin on the blood supply and oxygen metabolism of the brain.	the effect of benactyzine and spasmolytin adiphenine on the blood circulation in the oxygen consumption by the brain were investigated in experiments on dogs. the resulting data point to a biphasic action of benacyzine and spasmolytin on the blood supply of the brain (after a short-lived increase of the blood flow a clearcut decline of it is noted). the oxygen intake from the blood varies irregularly. in chlorophos-poisoned dogs the oxygen absorption by the brain changes under the effect of bena ...	1978	26597
bacterial etiology of otitis media during the first six weeks of life.	tympanocentesis was performed on 70 infants who had otitis media during the first six weeks of life. the bacteria isolated from their middle-ear effusions were streptococcus pneumoniae (13 patients), neisseria catarrhalis (11 patients), hemophilus influenzae (ten patients), enterobacteriaceae (four patients), staphylococcus aureus (four patients), streptococci (groups a and b) (three patients), and pseudomonas aeruginosa (two patients). thirty patients (42.9%) had middle-ear effusions which did ...	1978	26735
a modified agar diffusion assay for amphotericin b.		1978	26759
liberation of cyanide from alpha-aminonitriles relative to amygdalin.	a series of aminoitriles have been synthesized and studied whose nonenzymatic dissociation with release of cyanide may be varied by modest alteration of their molecular structure from that obtained with nonenzymatic dissociation of amygdalin to that obtained from enzymatic dissociation of amygdalin by substantial quantities of beta-glucosidase. the relationship between such alterations in molecular structure and nonenzymatic dissociation is discussed. a combination of the results of these studie ...	1999	26797
type-iii allergic reactivity to diplococcus pneumoniae and encapsulated haemophilus influenzae in passively sensitized mice and rats.		1978	26860
effect of prior antibiotic therapy on concentrations of bacteria in csf.	a prospective study was done to determine the effect of prior antibiotic therapy on concentrations of bacteria in csf at the time of diagnosis. concentrations of haemophilus influenzae type b in csf of partially treated patients were significantly smaller than in csf of untreated patients. this was also true of patients with meningococcal meningitis, but no difference was observed between patients with pneumococcal meningitis. the identification of h influenzae by gram stain of csf was significa ...	1978	27090
neurochemical anatomy of the neuroendocrine hypothalamus. neurochemical anatomy of the hypothalamus.	microdissection techniques for isolated removal of the various regions of the hypothalamus as well as the individual hypothalamic nuclei are detailed. recent development of biochemical microassays have made it possible that the concentrations of neurohormones, neuropeptides, neurotransmitters and their related enzymes could be detected in such a small volume of brain tissue than the hypothalamic nuclei. data available of the hypothalamic distribution of above substances are summarized. the possi ...	1978	27266
which drug for hypertension?		2000	27282
immuno-stimulation by a ribosomal vaccine associated with a bacterial cell wall adjuvant in humans.	we have studied a new vaccine of ribosomal nature associated with glycoprotein cell walls from klebsiella pneumoniae which served as an immunoadjuvant. thus vaccine was administered by the aerosol route to working men free of any important disease, especially of respiratory disease. a total of 104 men working for the commissariat à l'energie atomique, all volunteers, were randomly placed into two groups. during the first period, 51 patients (group i) were vaccinated three times a week during 5 w ...	1978	27461
red cell oxygen affinity in fetal sheep: role of 2,3-dpg and adult hemoglobin.	studies were carried out during fetal life in sheep to determine the relationship of 2,3-diphosphoglycerate (dpg), the intracellular red cell and extracellular ph, and the switchover to adult hemoglobin synthesis in regulating the position of the fetal red cell oxygen-affinity curve in utero. adult hemoglobin first appeared near 120 days of gestation. the mean oxygen tension at which hemoglobin is half saturated (p50) prior to 120 days of gestation remained constant at 13.9 +/- 0.3 (sd) torr and ...	1978	27486
epr investigation of the mn(ii) binding sites in glutamine synthetase (escherichia coli w). i. high-affinity binding sites.		1978	27502
[characteristics of hemorrhagic fever in the patients treated in the university hospital for infectious diseases zagreb from 1964 to 1976 (author's transl)].		1999	27680
the leeuwenhoek lecture, 1977. mouse teratocarcinoma and mouse embryo.		1978	27802
regulation of blood ph in teleost fish.	the nature of ph changes with temperature is similar in both air-breathing and water-breathing poikilotherms having a ph-temperature slope of -0.015 to 0.020 u/degrees c. the means by which this is accomplished are quite different in the two groups. the air-breather behaves in vivo as a rosenthal, or constant co2 content system, with paco2 increasing at higher temperatures. the increase in paco2 is brought about by a reduction in the ration ve/mco2. the water-breather, on the other hand, does no ...	1999	27850
cerebral autoregulation in unconscious patients with brain injury.	in 18 unconscious patients with traumatic brain injury, the cerebral autoregulation was tested during the first 2-3 weeks after the acute trauma. regional cerebral blood flow (rcbf) was measured by the intra-arterial 133xenon washout method before and after an increase of about 20% in the mean arterial blood pressure (mabp) by angiotensin. the difference between mabp and intraventricular pressure (ivp) was used as cerebral perfusion pressure (pp). simultaneously, ventricular fluid ph, lactate an ...	1998	27938
effects of ph, ca, adh, and theophylline on kinetics of na entry in frog skin.	the short circuit current as a function of na concentration in both solutions was found to obey michaelis-menten kinetics under a variety of experimental conditions. values of maximal transport rate (im) and half-maximal na concentrations (kt) were determined from these experiments. three type of results were obtained: 1) im and kt both decreased by approximately the same fraction when the ph of both solutions was reduced by increasing pco2, 2) im decreased and kt increased when the external ph ...	1998	27988
tissue ph measurement proceedings.		1978	28161
on opiates, pain, and the nervous system.		1998	28493
na+-k+-activated adenosinetriphosphatase as a trigger in transmitter release.		1978	28496
leukokinetic studies in mediterranean kala azar.	two patients with acute kala azar were studied with df32p (diisopropylfluorophosphate) and three patients with 51cr (chromate) in an attempt to delineate the mechanism producing neutropenia in this disease. the granulocyte life span was found to be reduced in all the patients with exception of one who was studied during glucantim treatment. the surface radioactivity counts showed that the reduced granulocyte life span was due to pooling and probable destruction of granulocytes in the spleen and ...	1998	28657
research of the soluble microbial substances in organic fluids for the rapid diagnosis of some infections and particularly of bacterial meningitis (author's transl).	a number of immunological and non-immunological techniques have been recently used to detect soluble microbial substances in body fluids of patients with acute meningitis, bacteremia, and lobar pneumonia. by the immunological methods capsular highly polymerized polisaccharide group- or type-specific antigens of the most common c. n. s. pathogens (n. meningitidis a, b, and c; str. pneumoniae, h. influenzae type b, e. coli k1, mucoid pseudomonas, cryptococcus neoformans) can be detected and quanti ...	1977	28697
deoxycytidine: a morphine antagonist.	deoxycytidine antagonizes the analgesic action of morphine in the rat, morphine-induced respiratory depression in the rabbit and mitigates withdrawal in the dependent mouse. administration of deoxycytidine does not precipitate the abstinence syndrome in dependent mice, a property shared by certain other endogenous morphine antagonsits. cytidine and thymidine closely related in structure to deoxycytidine, are interchangeable with saline as controls, indicating a high degree of specificity in the ...	1978	28700
bacteriologic flora of aspiration-induced pulmonary infections.	the role of anaerobic and aerobic microorganisms in the genesis of pneumonia or lung abscess in patients with historical, clinical, and radiologic findings suggestive of aspiration was compared to their role in similar patients without these findings. bacterial specimens were obtained by transtracheal aspiration or thoracentesis. anaerobes were isolated in 100% of the patients who were aspiration-prone as contrasted with only 20% of those who were not. isolation of a single species or no growth ...	1975	28705
[german language work group for hand surgery. 2d basel hand surgery work conference, 24-25 june 1977. recent injuries of the finger joint and their late sequelae. etiology, diagnosis, treatment].		1998	28997
a spectral probe near the subunit catalytic site of glutamine synthetase from escherichia coli. reduced pyridoxal 5'-phosphate.enzyme complexes.	in order to label phosphate binding sites, unadenylylated glutamine synthetase from escherichia coli has been pyridoxylated by reacting the enzyme with pyridoxal 5'-phosphate followed by reduction of the schiff base with nabh4. a complete loss in mg2+-supported activity is associated with the incorporation of 3 eq of pyridoxal-p/subunit of the dodecamer. at this extent of modification, however, the pyridoxylated enzyme exhibits substantial mn2+-supported activity (with increased km values for at ...	1978	29046
state and rhythmic processes.		1978	29061
otitis media in infants less than 12 weeks of age: differing bacteriology among in-patients and out-patients.		1978	29086
the midwife and human prosperity.		1978	29283
evaluation of the counterimmunoelectrophoretic (cie) procedure in a clinical laboratory setting.	the counterimmunoelectrophoretic (cie) procedure was evaluated under clinical laboratory conditions to determine its validity and comparability with culture methods. the procedure was further evaluated to determine applicability to a variety of clinical samples. an inexpensive set-up was developed to utilize the cie procedure at bench level. results indicated the procedure to be sensitive in detecting haemophilus influenzae, type b, and neisseria meningitidis (meningococcus), group b. the proced ...	1978	29483
antibiotic resistance in streptococcus pneumoniae and haemophilus influenzae.		1978	29689
flufenamic acid inhibition of pge2 production by rectal mucosa in ulcerative colitis.		2001	29819
effects of psychotropic drugs on the spinal ventral root reflexes in cats. a comparison of the depressant actions in intact and spinal preparations (author's transl).	effects of the typical psychotropic drugs such as neuroleptics, tricyclic antidepressants and benzodiazepines on the monosynaptic reflex (msr) and polysynaptic reflex (psr) were investigated using intact and spinal cats. drugs used were chlorpromazine, levomepromazine, perphenazine, prochlorperazine, droperidol, haloperidol, amitriptyline, imipramine, diazepam and flurazepam. neuroleptics depressed the ventral root reflexes markedly to slightly in both preparations. the inhibitory effects of the ...	1978	29826
royal academy of medicine in ireland. section of biological sciences. proceedings of summer meeting held at university college, galway, 29th-30th june, 1978.		2001	29859
viruses and bacteria associated with acute respiratory illnesses in young children in general practice.	the results obtained and the laboratory methods used for the isolation of viruses and bacteria from malaysian children with acute respiratory illnesses seen in a private clinic are described. of the 65 children studied virus isolations were obtained from 26 children, bacteria from 10 and both virus and bacteria from another 5. the agents isolated were influenza viruses, parainfluenza viruses, adenoviruses, bordetella pertussis, streptococcus pneumoniae, haemophilus influenzae and staphylococcus ...	1978	30173
bacteriology of maxillary sinusitis in relation to quality of the retained secretion.	the bacteriological findings in 200 patients with acute maxillary sinusitis are reported. it is concluded that the sampling technique--by antral aspiration--is highly significant in the evaluation of the bacteriological background of sinusitis, whereas the anerobic transport of the sample seems to be of less importance. by aspiration the purulent secretion can be properly separated from the non-purulent secretion. pneumococci, h. influenzae and anaerobic bacteria can be isolated in about 90% of ...	1978	30255
bacterial meningitis: the beginning of the end.		1978	30281
growth yield and efficiency in chemosynthetic microorganisms.		2001	30389
the fluorescence of fluorescamine-amino acids.		2001	30402
antibiotic resistance in streptococcus pneumoniae and haemophilus influenzae.		1978	30516
european society of human genetics. abstracts from symposium on "chromosome structure and function". vienna, austria, may 5-7, 1978.		1978	30557
dipeptidylaminopeptidase and carboxypeptidase activities of the brush border of rabbit small intestine.		1978	30675
the absorption and sputum penetration of doxycycline.		1978	30746
microbiology of recurrent and chronic otitis media with effusion.	a study was conducted of 274 children who had recurrent acute or chronic otitis media with effusion. forty-five percent of the ears with effusion were found to contain bacteria, and 11% contained bacteria that were "probable pathogens" (s. pneumoniae, h. influenzae, and s. pyogenes). bacteria were also found in 40% of the ears without effusions. the type of organism found did not vary with the age of the patient studied or the season of the year. the significance of these bacteria in the etiolog ...	1978	30809
treatment of acute otitis media of infancy with cefaclor.	the emergence of ampicillin-resistant haemophilus as a clinical problem in otitis media necessitates a search for alternative, effective therapy. an orally absorbable cephalosporin derivative, cefaclor, is equally effective in vitro against ampicillin-susceptible and -resistant haemophilus and against other bacteria that cause acute otitis media. two dosage schedules of cefaclor (40 and 60 mg/kg/day) were evaluated in 95 infants with acute otitis media. bacterial origin was determined by a cultu ...	1978	31084
cigarette smoking: a dependence on high-nicotine boli.		2001	31270