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patterns of shigella species and serotypes in east africa. 1979391541
effects of 19-hydroxy-prostaglandins on oviductal and uterine motility.the effects of 19-hydroxyprostaglandins (19-oh-pgs) were tested in vivo on the rabbit oviduct and uterus and on the rhesus monkey (macaca mulatta) uterus. the 19-oh-pges suppressed spontaneous oviductal and uterine activity in the rabbit. the qualitative effect on the rabbit oviduct of 19-oh-pges was similar to that of pge2. however, the typical response of the rabbit uterus to pge2 was an increase in muscle activity. with regard to the rabbit oviduct, 19(r)-oh-pge2 was as potent as pge2, but 19 ...1977404673
the aetiology and outcome of abruptio placentae.a series of 193 cases of abruptio placentae in a hospital population of 35,217 is described. this is an incidence of 0.55%. in the series both age and parity, but not pre-eclampsia or anaemia, are significant associated factors. the recurrence rate of abruptio placentae was 5.6%. there were no maternal deaths and the perinatal mortality was 35%. epidural analgesia does not abolish the pain of the abruptio placentae in spite of abolishing the pain of labour.2004419953
[measurements of sputum viscoelasticity using conventional dynamic measurements and the newly developed raised cosine pulse method (author's transl,]. 2004522300
[lesion of the collateral ulnar ligament of the thumb]. 2005546527
influence of portocaval anastomosis on lipid parameters in patients with alcoholic cirrhosis.the effect of portocaval shunt operation on lipid metabolism was investigated in 10 patients with alcoholic cirrhosis. portocaval shunt operation resulted in a significant decrease of concentration of total serum cholesterol, total serum triglycerides, ldl cholesterol, vldl cholesterol, vldl triglycerides, and lcat activity. the concentrations of free cholesterol, esterified cholesterol, phospholipids, ldl triglycerides, hdl cholesterol, and hdl triglycerides were unaffected.2005547323
[functional and radiological aspects of the coronary venous phase]. 2005548099
[bacteriological and epidemiological considerations on shigelloses in south vietnam (1969-1973)].during the period from 1969 to 1973, a rectal swabs from 13.943 diarrhea patients of all ages were examined by bacteriological surveys. from these specimens, 981 strains of shigella were isolated. the most commonly encounted were shigella flexneri 2. all of strains of shigella isolated were highly resistant to aureomycin, tetracyclin, terramycin, novobiocin and chloramphenicol. there has been an increase in the development of multiresistance of shigella. colimycin and streptomycin were the most ...1975770024
strain-related differences in immunosuppressive effects of enterobacteriaceae and their lipopolysaccharides on production in rabbits of antibody to enterobacterial common antigen.certain polysaccharides have been shown to inhibit the antibody response of rabbits to the common enterobacterial antigen (ca). the present investigation revealed that striking differences exist in the immunosuppressive effects of enteric bacteria and their lipolysaccharides (lps), depending upon ca production by the strains. mixtures of immunogenic strains (escherichia coli f2378 [r4], e. coli f470 [r1], or shigella boydii f3140 [r]) and non-immunogenic ca-producing strains, such as e. coli o1, ...1976776827
[shigellosis in tucumán].in 731 diarrhea cases studied from january 1971 to june 1973 in tucumán a significant increase of shigellosis in eutrophic children was observed. the frequency of shigella isolations, considering all the enteropathogens found, were: 15,5 %; 13 % and 21,3 % in 1971, 1972 and 1973, respectively (table 1). all the strains of shigella isolated belonged to the shigella flexneri b or shigella sonnei d groups, being the percentage for the former 78 % in 1971; 93 % in 1972 and 77 % in 1973 (table 2). th ...1975790480
shigellosis in the united states: ten-year review of nationwide surveillance, 1964-1973.in the 10 years 1964-1973, 105,832 isolations of shigellae were reported to the center for disease control through a nationwide surveillance system. the number reported increased by approximately 13% annually, from 5852 in 1964, when only 17 centers reported all 4 quarters; to 16,797 in 1973, when 52 centers reported each quarter. the rate of reported isolations varied from 4.6 per 100,000 persons in 1965 to 9.1 per 100,000 in 1973. shigella sonnei accounted for 64% of all these isolates and for ...1976790947
a case of severe bacillary dysentery caused by a gas-producing shigella boydii type 14 (enterobacterium a12 (sachs)). 1976792615
in-vitro effect of edta-tris-lysozyme solutions on selected pathogenic bacteria.the in-vitro effect of edta-tris-lysozyme solution on 16 pathogenic bacteria of medical or veterinary importance was determined. marked decreases in bacterial count occurred with pseudomonas aeruginosa, escherichia coli, moraxella osloensis and campylobacter fetus, and smaller decreses with salmonella typhimurium, shigella boydii, aeromonas hydrophila, proteus mirabilis, listeria monocytogenes and erysipelothrix insidiosa. the test solution had no effect on klebsiella ozaenae, brucella canis, co ...1975805241
working together for our future. 20051065213
effects of thymectomy and antithymocyte serum on spontaneous regression of friend virus-induced erythroleukemia.to evaluate the role of immune response in regression of leukemia, we studied the effect of immunosuppression on the spontaneous regression of a leukemia induced by a specific strain of friend murine leukemia virus complex (rfv). thymectomy of newborn but not adult outbred swiss mice markedly inhibited regression. the effect of antithymocyte serum (ats) on regression depended on the timing of ats treatment. regression was markedly inhibited in leukemic mice given ats just before the start of reg ...19761087346
antimicrobial resistance of shigellae isolated in michigan.patterns of antimicrobial resistance were studied for 213 strains of shigellae isolated in rural and urban areas of michigan by quantitative techniques: 66% of these organisms were resistant to ampicillin, tetracycline, cephalexin, or chloramphenicol or had multiple resistance to various combinations of these antibiotics. the incidence of resistant organisms was higher in the detroit-wayne county area, which is the most urban part of the state. nalidixic acid and oxolinic acid were noted to be q ...19751089819
observations on the serologic changes in the recombinants in shigella flexneri serotype 4a.studies on the antigenic composition of 84 diagnostic strains of s. flexneri serotype 4a and their lac+ recombinants from a cross with e. coli hfrc were carried out. considerable differentiation of agglutination reaction was found both in original material and in recombinants. an interesting group included recombinants which completely lost their capability to agglutinate with sera specific for type and group antigens and preserved only the capability to agglutinate in the polyvalent serum of s. ...19751090112
occurrence of the bacteriophage lambda receptor in some enterobacteriaceae.in escherichia coli k-12, the receptor for phage lambda is an outer membrane protein which inactivates the phage in vitro. lambda receptor activity was found in extracts from all wild strains of e. coli tested, although most of them fail to support growth of the phage. in some cases this failure is due to a masking of the receptor in vivo, the bacteria being unable to adsorb the phage or to react with antireceptor antibodies. in other cases, adsorption does occur, and the nature of the block in ...19751090748
[sensitivity of different strains of e. coli and shigella to the inhibitory action of ploskirev's bactoagar].a study was made of the sensitivity of 190 strains of e. coli and 107 strains of shigellae of different serological types to the inhibitory action of ploskirev's bactoagar on the capacity of these bacteria to form colonies. the strains under study proved to be nonhomogenous in this respect: between different strains of e. coli there were revealed 10-, 100- and even 1000-fold differences by this property; the differences between shigellae strains were less marked--in over 90% of shigellae strains ...19751092090
superiority of macconkey's agar over salmonella-shigella agar for isolation of shigella dysenteriae type 1.the efficiency of macconkey's agar in the isolation of various types of shigella was compared with that of salmonella-shigella (ss) agar during an extensive 18-month outbreak of disease caused by shigella. in all, 1,580 isolates of shigella were obtained from 12,307 rectal swab and fecal samples of patients with diarrhea and their contacts by direct plating onto macconkey's and ss agars. shigella dysenteriae type 1 and shigella flexneri constituted 55 percent and 33 percent of all isolates, resp ...19751094073
shigella strains associated with infantile diarrhea in the kaohsiung area.in 1969 and 1974, 375 shigella strains were isolated in the kaohsiung area, and their serotypes and in vitro susceptibility to antimicorbial agents were studied. in 1969, 249 (16.2%) strains were isolated from 1,476 specimens collected from infantile and young children dirrheal cases, whereas 126 strains (11.6%) were isolated from 1,086 specimens in 1969. the isolation rates were higher in may (21.2%), october (20.8%), april (20.6%), august (19.7), november (18.8%) and january (18.5%), than in o ...19751097211
[antigenic relationships between "levinea amalonatica" and "shigella dysenteriae" and "boydii" (author's transl)].twenty-eight strains among thirty-five levinea amalonatica show o antigenic relationships with shigella as follows: with s. dysenteriae 3 (5 strains), s. dysenteriae 4 (1 strain), s. dysenteriae 5 (3 strains), s. dysenteriae 7 (11 strains), s. boydii 6 (7 strains), and with both s. boydii 15 and s. dysenteriae 8 (1 strain). these strains do not induce purulent keratogenous conjunctivitis in guinea pigs as shigella do.19751098541
effect of plasma protein binding on elimination of bilirubin. 19751151726
the forgotten treatment modality in bipolar illness: psychotherapy.the author presents 31 bipolar patients treated with combined lithium prophylaxis and psychotherapy for up to 41 months. the grave prognosis of untreated bipolar illness is reviewed. the improved prognosis with lithium prophylaxis alone is reviewed. the author demonstrates an improved prognosis when lithium prophylaxis is combined with psychotherapy and discusses his findings as to why lithium prophylaxis alone still predicts a grave outcome.20051183307
circadian properties of the rhythmic system in individual nucleated and enucleated cells of acetabularia mediterranea. 20051248525
editorial: who owns your medical records? 20051262726
neonatal tetanus: a developmental follow-up study. 20051278947
[bacteriology of shigella isolated in a tropical zone chu].from 1981 to 1991, five hundred eighty one shigella's strains were isolated in the laboratories of the chu fann of dakar. they represent 24.8 per cent of enteropathogen agents and 4.3 per cent of diarrhoeae causative agents. shigella flexneri was predominant (71%), following by shigella dysenteriae (14.5%), shigella sonnei (11.4%) and shigella boydii (2.5%). in pediatric hospital 90 per cent of strains were isolated between 1 and 5 years age; in adults, the pic was found from 20 to 30 years. fiv ...19921345084
sexual transmission of htlv infections in southern india. 19921346809
[lipid and mineral metabolism and morbidity with temporary loss of work capacity in miners].examination is performed on 87 miners from mine for copper production subject to intensive local vibrations with average rate of increase (k) of the norms for the individual octave frequencies 2.4 times for 3 h exposure of the working shift, as well as to intensive noise--113-115 db/a equivalent level, general dust--23 mg/m3, fine dust--3.5 mg/m3 and fine quartz--0.43 mg/m3. there are data for vibration effect--changes in the cold test, vibration sensoriness, ultra sound sonometry, in all miners ...20051364539
the vascular endothelial growth factor proteins: identification of biologically relevant regions by neutralizing monoclonal antibodies.angiogenesis plays critical roles in organ development during embryonic and fetal life, wound healing and in a variety of pathological conditions. vascular endothelial growth factor (vegf) is a secreted growth factor specific for vascular endothelial cells which induces angiogenesis in vivo. to gain a better understanding of the physiological role of vegf, we have generated and characterized four murine monoclonal antibodies (mabs) using the 165 amino acid species of recombinant human vegf as im ...19921380254
health checks on patients 75 years and over in nottinghamshire after the new gp contract.to investigate annual health checks for patients of 75 years and over required by the 1990 contract for general practitioners.20061393076
concentration of milk secretory immunoglobulin a against shigella virulence plasmid-associated antigens as a predictor of symptom status in shigella-infected breast-fed infants.we conducted a prospective, community-based study of healthy breast-fed mexican infants to determine the protective effects of anti-shigella secretory iga antibodies in milk. milk samples were collected monthly, and stool culture specimens were obtained weekly and at the time of episodes of diarrhea. nineteen breast-fed infants were found to have shigella flexneri, shigella boydii, or shigella sonnei in stool samples. ages of the 10 infants with symptomatic infection and the nine with asymptomat ...19921447644
shigellosis in children: a prospective hospital based study.from 1985 to 1988, fecal samples of 950 hospitalized children suffering from diarrhea or dysentery were screened for shigella species using standard methods. shigella species were isolated as sole pathogen from 192 (20.2%) cases and s. flexneri type 2 was the predominant serotype. shigella infection was prevalent throughout the year with high isolation rate during the summer and early monsoon months. shigella strains isolated during the period were resistant to most of the commonly used drugs fo ...19921452309
[the etiological structure of shigellosis in the former ussr--an indicator of the activity of the main routes of infection transmission].the data on the etiological structure of shigella infections in the ussr in 1988-1989 are presented. the study showed the dominating role of s. flexneri with s. sonnei also retaining great importance in shigella infections. the process of the liquidation of s. dysenteriae and s. boydii infections began in some large cities. the domination of dysentery caused by s. flexneri and a high typhoid rate, particularly in central asia, were due to poor water supply of the population. the spread of dysent ...19921455964
[the theoretical and practical interpretations of the basic manifestations of the epidemic process in shigellosis]. 19921466177
[bacillary dysentery--1990]. 19921475396
asbestos: the turbulent interface between science and policy. 20061489439
[major hypereosinophilia disclosing colonic cancer]. 20061533927
drug resistance and plasmid profile of shigellae in taiwan.one hundred and twenty-eight shigella strains isolated from newborn and infant human faecal specimens at kaohsiung medical college hospital in taiwan were serogrouped, serotyped and examined for drug-resistance patterns and for the presence of plasmids. forty-seven per cent of the isolates were found to belong to the shigella sonnei serogroup, 41% to the s. flexneri group, 9% to the s. boydii group and 3% to the s. dysenteriae group. the serotype with the greatest number of strains was s. sonnei ...19921547844
bioactive polymers: in vitro and in vivo study of controlled release neomycin.neomycin is coupled on xanthan-a polysaccharide of microbial biosynthesis produced by xanthomonas campestris-through ionic complexation. the kinetics of neomycin release, in vitro, at ph = 8.2 is studied. a controlled release of neomycin, following a zero order kinetics is observed, regardless of the eluent flow. neomycin complexed on xanthan, administered in a unique daily dose to patients suffering from dysentery in the 100 cases taken in study, has shown a high clinical efficiency as compared ...19921573555
characterization of aeromonas caviae antigens which cross-react with shigella boydii 5.live and boiled cells of 16 strains of aeromonas caviae, isolated from patients with diarrhea, agglutinated with shigella boydii 5 antiserum in a slide test. further studies with seven selected strains showed agglutination with boiled cells in a tube test. lipopolysaccharide antigen extracted from one of these strains cross-reacted with s. boydii 5 in enzyme-linked immunosorbent assay and immunoblot studies. either all or the majority of the seven strains possessed properties deemed to be diarrh ...19921583145
identification and analysis of the gene encoding human pc2, a prohormone convertase expressed in neuroendocrine tissues.in recent studies we have identified pc2 and pc3, members of a family of serine proteases that are related structurally to subtilisin, and have provided evidence that these are involved in the tissue-specific processing of prohormones and neuropeptides. pc2 is expressed at high levels in the islets of langerhans, where it participates in the processing of proinsulin to insulin (s.p.s. and d.f.s., unpublished data). to evaluate the regulated expression of the human pc2 (hpc2) gene we have analyze ...19921594602
acamprosate modulates synaptosomal gaba transmission in chronically alcoholised rats.male sprague-dawley rats were pulmonary alcoholised for 30 days. six were treated with acamprosate (400 mg/kg/day, po) during alcoholisation. the control nonalcoholised group also received acamprosate (400 mg/kg/day, po) during the 30 days. at the end of the experiment, brains areas (cortex, hippocampus, thalamus, striatum, and olfactory bulbs) were dissected for the study of synaptosomal 3h-gaba uptake. in another experiment, gaba levels were determined in the same areas using hplc with electro ...19921594633
copulatory analgesia in male rats ensues from arousal, motor activity, and genital stimulation: blockage by manipulation and restraint.the effect of copulation on the vocalization threshold to tail shock (vtts) was assessed in freely-moving, sexually experienced, wistar male rats. mean vtts during the first copulation was 40% above the baseline values and slightly decreased during the first postejaculatory interval (pei; 28% above baseline). vtts mean values further increased during the second copulatory series (93% above baseline and 63% during the pei). testing at the same intervals in noncopulating rats did not induce analge ...19921594675
estimating the probability of spontaneous abortion in the presence of induced abortion and vice versa.an integrated approach to estimate the total number of pregnancies that begin in a population during one calendar year and the probability of spontaneous abortion is described. this includes an indirect estimate of the number of pregnancies that result in spontaneous abortions. the method simultaneously takes into account the proportion of induced abortions that are censored by spontaneous abortions and vice versa in order to estimate the true annual number of spontaneous and induced abortions f ...20061594736
[obesity. various aspects in daily practice].overweight and obesity are the most often encountered disease conditions in general practice. recent evidence of the importance of fat distribution is discussed. the basic therapeutic approach for the most effective therapy of obesity is probably the combination of a dietary (hypocaloric), a behavioral and a physical activity approach. in this general overview the physiologic background of abdominal obesity and some selected therapeutic implications are discussed.20061594849
molecular epidemiology of trimethoprim-resistant shigella boydii serotype 2 strains from bulgaria.in 1990 an increased number of strains of shigella boydii serotype 2 were isolated from different regions of bulgaria. strains were reported as sporadic, although they showed identical phenotypic characteristics, including resistance to ampicillin, carbenicillin, streptomycin, sulfonamide, tetracycline, ticarcillin, and trimethoprim. the objective of this study was to determine the genetic relatedness of the strains and the mechanism of their antimicrobial resistance. plasmid fingerprinting show ...19921624559
monoclonal antibodies to quebec strain (q17) of bovine rotavirus.fourteen monoclonal antibodies (mabs) against "quebec" strain (q17) of bovine rotavirus were isolated and characterized. four were specific for viral protein vp7 and ten were specific for viral protein vp6. five different isotypes were represented by this group of antibodies. all of the anti-vp6 and none of the anti-vp7 antibodies were sensitive to the effects of periodate on their antigen. the antibodies could be separated into three groups based on their relative resistance to the dissociation ...19901698323
transient cytokeratin expression in skeletal muscle during murine embryogenesis.cytokeratin expression was investigated in paravertebral skeletal musculature of 10 d and 18 d old embryos as well as in adult nmri-mice. the muscular nature of the evaluated tissue was evidenced by their expression of vimentin and desmin. binding moieties for cytokeratin antibodies (polyclonal and monoclonal) could be demonstrated only in muscle cells of 10 d old embryos. concerning subtypes, the mouse equivalents of the human cytokeratins nos. 8, 18 and 19 could be made probable. the importanc ...19901698345
decreased monocyte-induced angiogenesis in scleroderma. 20061698391
conduction velocity distribution of afferent fibers innervating the rat urinary bladder.the conduction velocities of individual afferent fibers innervating the rat urinary bladder were determined by the antidromic stimulation of dorsal roots while recording from bladder postganglionic nerves. conduction velocities ranged from 0.5 to 21.0 m/s; 70% of the velocities were less than 2.5 m/s. the distribution within the dorsal roots was ipsilateral with 84% in l6 and 16% in s1. neuroanatomical tracing with horseradish peroxidase applied to individual bladder postganglionic nerves result ...19901698508
characterization of shigella dysenteriae serotypes 11, 12, and 13.we conducted serologic and biochemical studies on strains of three provisional shigella serotypes. included were 19 strains of serotype 3873-50 from three countries (1 from mexico, 1 from netherlands antilles, and 17 from the united states), 13 strains of serotype 3341-55 from three countries (1 from canada, 1 from bulgaria, and 11 from the united states), and 19 strains of serotype 19809-73 from two countries (16 from israel and 3 from the united states). reactions of these strains with homolog ...19901701447
[antigenic polysaccharides of shigella bacteria. structure of the polysaccharide chain of the lipopolysaccharide from shigella boydii, type 11].on mild acid degradation of the shigella boydii, type 11 lipopolysaccharide, the corresponding o-specific polysaccharide composed of d-glucuronic acid, 2-acetylamino-2-deoxy-d-glucose, d-ribose and l-rhamnose residues in the ratio 1:1:1:3 was obtained. methylation, partial acid hydrolysis and 13c-nmr spectral data for the polysaccharide led to the structure of the oligosaccharide repeating unit as a branched hexasaccharide: [formula: see text]. numerous o-acetyl groups attached non-stoichiometri ...19911712200
relatedness of o-specific lipopolysaccharide side chain genes from strains of shigella boydii type 12 belonging to two clonal groups and from escherichia coli o7:k1.the o-specific lipopolysaccharide side chains of escherichia coli o7 and shigella boydii type 12 possess similar but not identical chemical structures. we investigated the genetic relatedness between the o-specific side chain genes in members of these two species. examination of outer membrane protein and lipopolysaccharide (lps) banding patterns demonstrated that five strains which had been identified as s. boydii type 12 fell into two clonal groups, sb1 and sb2. hybridizations with o7-specific ...19911718868
possible mechanisms underlying the slow lactose fermentation phenotype in shigella spp.a southern hybridization analysis revealed that the region homologous to escherichia coli lacz was present on the chromosomal dnas of beta-galactosidase-positive shigella strains, such as shigella dysenteriae serovar 1 and shigella sonnei strains, whereas this region was absent from chromosomal dnas of beta-galactosidase-negative strains of shigella flexneri and shigella boydii. we found that the lacy-a region was deficient in s. dysenteriae serovar 1 and believe that this is the reason for the ...19911746953
contact-haemolysin production by entero-invasive escherichia coli and shigellae.entero-invasive escherichia coli (eiec) and shigellae were tested for contact-haemolysin (ch) with red blood cells (rbcs) of guinea-pig, rabbit, rat, mouse, monkey, man, sheep and chicken; all bacteria showed the best lysis with guinea-pig rbcs. the best culture medium for ch activity of shigellae was tryptic soy broth, and for eiec it was casamino acid-yeast extract broth with 1 mm cacl2. ch production by all species was best at the slightly alkaline ph which is optimal for growth; it was also ...19911753390
antimicrobial resistance trends of shigellae isolates from calabar, nigeria.during a 3-year study (january 1986-december 1988), stools of 2200 diarrhoeal or dysenteric patients were examined by culturing and 108 (4.9%) were found positive for shigellae. shigella flexneri was the commonest species isolated (54.6%), followed by sh. dysenteriae (24.1%). patients aged less than or equal to 15 years accounted for 51.4% of cases. shigellae over the 3 years showed high and sometimes rising resistance to ampicillin, chloramphenicol, streptomycin and cotrimoxazole and complete r ...19911758013
plasmid-associated resistance to pivmecillinam in shigella flexneri and shigella boydii. 19911761454
[case study reports, no. 181 (society for scientific nursing)]. 20061764935
development of an in vitro microtest to assess drug susceptibility of babesia bovis and babesia bigemina.continuous cultivation of the bovine hemoparasites babesia bovis and babesia bigemina was developed as an in vitro microtest to assess parasite susceptibility to babesicidal compounds. reproducibility of parasite multiplication rates was independent of culture size, making it possible to use a microscale of 100 microliters for each test sample. inhibitory concentrations (ic50s) of a commonly used babesicide, quinuronium sulfate, evaluated by this in vitro method were found to be 5 x 10(-8) g/ml ...19911779305
[continuous noninvasive recording of circulatory parameters while performing the valsalva test under elevated ambient pressure].the results are presented which confirm applicability of the valsalva test as a functional exercise for the cardiovascular system while studying changes of the circulation regulation under high ambient pressure. methods of transthoracic tetrapolar impedance plethysmography, electro- and intervalocardiography and mean arterial pressure measurement by means of the oscillometric servosystem are shown as adequate and highly informative under these conditions.20051790814
on the regulation of collagen-fibril shape and form. 20061794563
transcatheter management of pseudoaneurysms complicating pancreatitis.hemorrhage from rupture of an arterial pseudoaneurysm is a potentially fatal complication of pancreatitis. seventeen patients underwent transcatheter embolization of 23 arteries for the treatment of 20 arterial pseudoaneurysms secondary to pancreatitis. their records were reviewed retrospectively to evaluate the clinical benefit of transcatheter therapy. at presentation, 15 of the 17 patients had gastrointestinal, intrasplenic, retroperitoneal, intraperitoneal, or postoperative wound bleeding. t ...20061797219
transcatheter management of pseudoaneurysms complicating pancreatitis.hemorrhage from rupture of an arterial pseudoaneurysm is a potentially fatal complication of pancreatitis. seventeen patients underwent transcatheter embolization of 23 arteries for the treatment of 20 arterial pseudoaneurysms secondary to pancreatitis. their records were reviewed retrospectively to evaluate the clinical benefit of transcatheter therapy. at presentation, 15 of the 17 patients had gastrointestinal, intrasplenic, retroperitoneal, intraperitoneal, or postoperative wound bleeding. t ...20061797219
furosemide inhibits the centrally-mediated pressor response to clonidine in conscious, normotensive rats.1. the effect of furosemide on the pressor response induced by intracerebroventricular (i.c.v.) injection of clonidine was investigated in freely moving, normotensive rats with chronically implanted arterial catheters. 2. when injected i.c.v., clonidine at doses of 5 and 10 micrograms produced a dose-dependent pressor response and a decrease in heart rate. no depressor response was induced by clonidine. 3. systemic (i.v.) pretreatment with furosemide (2-10 mg kg-1) increased urine volume and dos ...19911797326
serotype distribution and antimicrobial resistance of shigella isolates in singapore.serogrouping of 506 shigella strains isolated in singapore from 1986 to 1990 showed that shigella flexneri (60.3%) was the most common, followed by s. sonnei (33.6%), s. boydii (3.2%) and s. dysenteriae (3%). of the 23 shigella serotypes identified, the predominant ones were s. flexneri types 2a and 1b, s. boydii types 1 and 5, and s. dysenteriae types 1 and 3. more than 80% of the shigella species were resistant to at least one antimicrobial drug, and the incidence of multiresistance was partic ...19911800565
[the structure and absolute configuration of isorupestonic acid from artemisia rupestris l].a new sesquiterpene compound named isorupestonic acid was isolated from artemisia rupestris and its absolute stereostructure was elucidated as 3b by spectral and x-ray crystallographic methods. interestingly, the isorupestonic acid is based upon an unusual 6, 7 membered ring skeleton differing from the 5, 7 membered ring rupestonic acid although both have the same absolute configuration at c-1. the biogenesis of isorupestonic acid most likely involves breaking the c4-c5 bond of rupestonic skelet ...20071805508
[the functional status of the endocrine pancreas in patients with acute intestinal infections].ria was used to measure the content of insulin, c-peptide and glucagon in blood plasma of 84 patients with acute dysentery and food toxicoinfections. the studies were carried out in the acute disease period and before the discharge from hospital. the data obtained indicate that despite the appreciable differences in the disease pathogenesis, the pathophysiological mechanisms influencing pancreatic function are similar in many respects. the changes are characterized by an increase in plasma insul ...19911810055
molecular epidemiology of shigella infections: plasmid profiles, serotype correlation, and restriction endonuclease analysis.plasmid isolation was used to refine the epidemiologic analysis for 168 shigellosis cases in pima county, ariz. plasmids of less than 20 kb were used for comparison of plasmid profiles. plasmid patterns for each species were distinct. a total of 57 of 74 (77%) shigella flexneri strains could be placed into seven plasmid patterns, 70 of 79 (89%) shigella sonnei strains could be placed into seven patterns, 12 shigella boydii strains could be placed into six patterns, and each of 3 shigella dysente ...19911847148
absence of na+,k(+)-atpase regulation of endosomal acidification in k562 erythroleukemia cells. analysis via inhibition of transferrin recycling by low temperatures.transferrin (tf) acidification has been shown to be limited to ph 6 in murine balb/c 3t3 fibroblasts, human a549 epidermoid carcinoma cells, and chinese hamster ovary cells and is followed by alkalinization during recycling. in contrast, tf acidification in the human erythroleukemic cell line k562 proceeds to below ph 5.5, and alkalinization of internal tf during recycling is not observed. to explore the regulation of endosomal ph in k562 cells, we determined whether the existence of an early en ...19911847374
olfactory dysfunction in parkinson's disease.an olfactory function test in 18 patients with parkinson's disease (pd) and 10 age-matched control subjects was performed. both detection and recognition thresholds were measured with five kinds of synthesized odorants (t & t olfactometry). before each test, rhinoscopic inspections were performed to exclude subjects who could have respiratory hyposmia. both detection and recognition thresholds in patients with pd were significantly elevated in comparison with those of control subjects. auditory ...20071852411
perfusion characteristics of hepatic cavernous hemangioma using intravenous ct angiography (ivcta).thirty-three patients with 35 proven hepatic cavernous hemangiomas (hch) were studied with intravenous ct angiography (ivcta). 15 scans were performed during the first 30 s after bolus (6 ml/s) injection of 50 ml iodinated contrast material. thereafter 2 scans/min were obtained up to 30 min. three criteria were utilized at ivcta to make a specific diagnosis of hch: (1) detection of an intense mural nodular enhancement in the arterial phase. the density in the nodular region(s) should have a dens ...20071855518
n-nitroso compounds, genotoxins and their precursors in gastric juice from humans with and without precancerous lesions of the stomach.we are investigating the interrelationships between levels of total n-nitroso compounds (noc), genotoxic activity (both before and after nitrosation), degree of bacterial colonization in gastric juice and degree of severity or absence of precancerous lesions of the stomach. the mean level of constitutive total noc in gastric juice was similar in the different groups of patients, but it was higher in acidic gastric juice (n = 30) than in gastric juice at ph greater than 4.5 (n = 12). acid-catalys ...20071855844
replantation in children.the authors have replanted 162 parts in 120 children over the past 15 years. the youngest patient, undergoing successful replantation, was aged 7 months, 3 weeks. unlike an adult, any child suffering a traumatic amputation should be considered for a possible replantation. replantation should consist of minimal bone shortening to preserve epiphyseal plates, with repair of all severed structures. longitudinal k-wires usually provide adequate fixation. our survival rate for complete replantation in ...20071865815
in the aftermath: health care in kuwait city. 20071865865
simultaneous infection with multiple serotypes of shigellae in a patient.we isolated three different serotypes of shigella on admission from a patient with dysentery as well as a shigella-like organism and campylobacter jejuni upon follow-up. the patient produced serum antibodies to all three serotypes of shigellae.19911889185
["masked" autoantibodies from the serum of healthy blood donors cross-reacting with dna and bacterial lipopolysaccharides].the "masked" autoantibodies with polyspecific activity were found in the serum of healthy donors. it is shown that these antibodies are able to react with antigens after the ion exchange chromatography with qae-sephadex. it was found that these "masked" antibodies are able to cross-react with dna and lipopolysaccharides of wide-spread species of bacteria. the possible role of these antibodies as in protection of organism from the external antigens as in the origin of autoimmune diseases is discu ...19911908720
[the effect of tetracycline and vitamin e on energy metabolism in cardiac mitochondria of old rabbits pretreated with isoproterenol].the possibility of eliminating adverse effects of tetracycline and isoproterenol pretreatment on energy generation of myocardial mitochondria by vitamin e administration was investigated in old rabbits. vitamin e administered in doses of 1.5 mg per kg body weight over 6 days was found to improve energy metabolism in old rabbits whose metabolism had been deranged by isoproterenol pretreatment in the dose of 1.5 mg per kg body weight. subsequent administration of vitamin e to rabbits pretreated wi ...19911913199
[mr tomography of aneurysmal bone cyst].the preoperative findings of magnetic resonance imaging (mri) in six histology-proven aneurysmal bone cysts (abc) are examined and compared with previous publications concerning mri of abc. the signal intensities differ considerably, and not all of our cases conform with the literature data. they can be summarised in three different subheadings: one form that is very inhomogeneous in t1- and t2-weighting, with fluid-fluid levels in the cystic spaces; one intermediate form without fluid-fluid lev ...20071932722
reactive modifications of the autonomous time structure in the human organism.the spectrum of biological rhythms exhibits characteristic principles of biological time structure which also rule the functional behaviour. with increasing period lengths the rhythms become increasingly complex. in the long-wave section the rhythmic functions find their corresponding cycles in the environment, whereas the shorter waves represent only endogenous autonomous rhythms, which maintain an internal time order by means of frequency- and phase-coordination. under resting conditions and i ...19911932773
a new role for radiologists in the development of cardiac surgery. 20071950902
esophageal function and dysfunction. 20071951923
inhibition by anti-cd2 monoclonal antibodies of anti-cd3-induced t cell-dependent b cell activation.anti-cd3 mab can activate t cells to help in b cell activation as detected by late events, such as maturation of b cells into ig-secreting cells (igsc), or by early events, such as b cell surface expression of the activation marker cd23. two different anti-cd2 mab each inhibited anti-cd3-induced t cell-dependent b cell activation in a dose-dependent fashion. neither irradiation of the t cells prior to culture nor depletion of cd8+ cells abrogated the inhibitory effects of anti-cd2 mab. despite t ...20071976440
pathogenicity of foodborne salmonella.salmonella remains a leading etiological agent in bacterial foodborne diseases. although human salmonellosis generally presents as a self-limiting episode of enterocolitis, the disease can degenerate into chronic and debilitating conditions. antibiotic treatment of uncomplicated salmonellosis is contra-indicated because it tends to prolong the carrier state. clinical management of systemic infections with newer drugs such as third-generation cephalosporins and quinolones is most promising, parti ...19912018704
four decades of shigellosis in israel: epidemiology of a growing public health problem.despite the improved standard of living in israel, shigellosis remains a common disease. examination of trends in the incidence of shigellosis in israel between 1951 and 1987 showed a period of declining rates followed by an increase in the reported incidence beginning around 1969. this increase was mainly due to shigella sonnei; rates of infection with shigella flexneri remained relatively constant. trends showed marked differences between age groups and between ethnic groups. in comparison, th ...19912041956
a weak adaptive response to alkylation damage in salmonella typhimurium.an efficient adaptive response to alkylation damage was observed in several enterobacterial species, including klebsiella aerogenes, shigella sonnei, shigella boydii, escherichia alkalescens, escherichia hermanii, and escherichia fergusonii. increased o6-methylguanine-dna and methylphosphotriester-dna methyltransferase activities correlated with the induction of a 39-kda protein recognized by monoclonal antibodies raised against the escherichia coli ada protein. induced methyltransferase activit ...19912050626
site-specific recombinase genes in three shigella subgroups and nucleotide sequences of a pinb gene and an invertible b segment from shigella boydii.inversional switching systems in procaryotes are composed of an invertible dna segment and a site-specific recombinase gene adjacent to or contained in the segment. four related but functionally distinct systems have previously been characterized in detail: the salmonella typhimurium h segment-hin gene (h-hin), phage mu g-gin, phage p1 c-cin, and escherichia coli e14 p-pin. in this article we report the isolation and characterization of three new recombinase genes: pinb, pind, and defective pinf ...19912061288
[directions of an ethic in genetic engineering: evaluation of an ethic for biotechnology].a fundamentalistic point of view is for the evaluation of genetic engineering inadequate. using ethics to evaluate the consequences is not valid for gene transfers across species as a morally relevant criterion but is rather the assessment of toxic, pathogenic, and ecological effects of transgenic organisms. a criterion for human genetics is not the inviolability of the human embryo, but social and human tolerance and the consent of the affected.19902074899
nonsquamous tumors of the head and neck in the geriatric population.thyroid tumors, salivary gland tumors, and non-hodgkin's lymphoma are described. psychosocial issues involving the geriatric patient are discussed. case reports of a number of geriatric tumor patients are included.20072074986
[problem of clinico-roentgenological diagnosis of acute pneumonia in infants in their first few months of life].studies into the problems of diagnosing pneumonia in children of the first months of life carried out for many years have shown that pneumonia may be referred to the diseases with indefinite diagnostic criteria. in view of this fact the x-raying of the chest should be regarded as a method of varifying the diagnosis of pneumonia. the roentgenographic findings should be estimated bearing in mind the presence or lack of a syndrome such as bronchial obstruction and the epidemiological anamnesis data ...20072075041
[recurrent thromboembolism disclosing protein c deficiency. apropos of a case with familial investigation].every thromboembolic manifestation, especially in young subjects, calls for an aetiological study in which haemostasis is evaluated primarily with assays of physiological coagulation inhibitors: protein c, protein s and antithrombin iii. protein c deficiency is found in 6 to 7% of thromboembolic manifestations. we report the case of a 21-year old man who had phlebitis followed by pulmonary embolism without facilitating factors. protein c level was 50% of normal value (0.50 iu/ml). the patient re ...19902075365
[shigellosis]. 19902076763
[clinico-morphological comparisons in different types of dysentery].clinical evidence and morphological picture of rectal biopsy specimens were analysed for 125 dysentery patients. as compared to a light course, moderately severe and severe dysentery presented enhanced microbial adherence and an elevated level of large lymphocytes in the external epithelium of the rectum, deeper penetration of shigella into crypts. on day 9-15 of the disease in attenuation of the clinical symptoms in severe and moderately dysentery morphological shifts persisted whereas the ligh ...19902084341
palindromic unit highly repetitive dna sequences exhibit species specificity within enterobacteriaceae.palindromic units (pu, or rep for repetitive extragenic palindrome) constitute a family of dna sequences of 40 nucleotides which is highly repeated in the genome of escherichia coli. we analysed the presence of pu sequences in 99 different bacterial genomes by cross-hybridization. when pu sequences were used as a probe, only dna from enterobacteriaceae closely related to e. coli exhibited an appreciable hybridization signal: shigella sonnei, shigella boydii, salmonella enteritica serotype typhim ...19902092362
molecular analysis of strains of shigella boydii isolated in northern and southern italy.in the years 1981-1988, shigella boydii played a very limited role in the aetiology of diarrhoeal disease in italy. however, between september and november, 1985, 19 isolates of serotype 2 were recovered in northern italy from a dysentery outbreak which occurred in a geriatrics hospital in abbiategrasso (milan, lombardy) and seven were identified in southern italy during the period january-july, 1986 from apparently unrelated infection cases occurring in brindisi (apulia). these isolates were co ...19902092367
[health economics--stopgap measures are no decisions. interview by kaj nyman]. 20062095080
effects of chronic non-ketotic diabetes and aging on myocardial function and fatty acid oxidation.the effects of aging and chronic non-ketotic diabetes on contractile properties, oxygen consumption, palmitate oxidation and morphology were studied in isolated, perfused working hearts of 2, 9, 12 and 22 month old rats. the heart rate, coronary flow, and oxygen consumption were no different among the 9, 12 and 22 month control and diabetic hearts. cardiac work was not depressed in control hearts until 22 months of age. depression of cardiac output due to aging in the control hearts progressed i ...19902141842
[antibiotic resistance of shigella isolated in the kara-kalpak a.s.s.r. 1987-1988].sensitivity of shigella spp. isolated in one of the hospitals of nukus within 1987-1988 and earlier in 1977 and 1985 was studied. s. flexneri 1-5 remained the main causative agents of dysentery on the territory. however, beginning from 1987 there were registered cases of dysentery caused by s. dysenteriae 1. the isolates were most sensitive to cefotaxime, cephaloridine, polymyxin b and gentamicin. the majority of the isolates were resistant to tetracycline, levomycetin (chloramphenicol) and stre ...19902144726
an attempt to structurally convert mu-selective morphine toward delta-receptor binding: dimerization based on enkephalin conformation.in order to elucidate the substrate specificities for mu- and delta-opioid receptors, dimerization of the mu-specific morphine molecule was attempted, based on the hypothesis of the possible relationship between the molecular conformation of endogenous enkephalin and its selectivity for each opioid receptor. the nor2 ([normorphine]n-ch2-ch2-n[normorphine]) thus synthesized exhibited agonist activity showing a preference for binding with the delta-opioid receptor, compared with the parent morphin ...19902164938
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