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requirement of heme for growth of bacteroides fragilis.heme or protoporphyrin ix was required for growth of bacteroides fragilis in a defined medium. the amount of heme necessary for half-maximal growth was 2 to 10 ng/ml (3.8 to 15 pmol/ml) among the bacteroides species and strains tested. the growth rate, metabolic products from glucose fermentation, and cell yields were affected by the concentration of heme in the medium and by the length of time the culture was incubated. when heme was growth limiting (4 ng/ml), growth rates decreased by 50%, cul ...1977921263
treatment of cerebral abscesses. 1977922393
bacteriological study of otogenic cerebral abscesses: chemotherapeutic role of metronidazole.in nine consecutive patients with otogenic cerebral abscesses a mixed growth of aerobic and obligate anaerobic bacteria was isolated from the pus in five patients, and in the remaining four obligate anaerobes were the sole isolates. the commonest obligate anaerobe isolated was bacteroides fragilis, which was present in all but one patient. the patients were all treated with metronidazole for the anaerobic organisms and with appropriate chemotherapy against the aerobic organisms isolated. all the ...1977922400
evaluation of kanamycin-esculin bile agar for isolation and presumptive identification of bacteroides fragilis group.a kanamycin-esculin bile medium was useful for selective isolation and presumptive identification (24 h) of the bacteroides fragilis group.1977925149
letter: treatment of a brain abscess due to bacteroides fragilis with metronidazole. 1976931828
[the bacteriodaceae flora in the faeces of pigs (author's transl)[].a total of 180 bacteroidaceae strains from the fecal specimens of 31 clinically healthy pigs aged 120 to 180 days from 4 farms were isolated in numbers of 10(8)-10(10) per gram feces and differentiated for their morphological, cultural and biochemical properties. 161 of these strains belonged to bacteroides ruminicola and related species, 10 to b. fragilis ss. fragilis, 3 to b. fragilis ss. vulgatus, 4 to fusobacterium necrogenes, 1 to f. mortiferum and 1 to a non-motile variant of f. novum. the ...1976936825
the use of pr-reduced media and a portable jar for the collection of anaerobic organisms for clinical sites of infection.a system for the isolation of anaerobic organisms from clinical specimens was evaluated at the lac-usc medical center. clinicians were provided with a gas pak with a broth tube and two prereduced blood plates for direct inoculation of specimens. in the first 50 patients evaluated, 74 separate anaerobic isolates were recovered in 36 patients, 72 per cent of the total. bacteroides fragilis was the most common organism recovered. the impact of this system upon clinical management is discussed.1976937393
carbenicillin in the treatment of infections involving anaerobic bacteria.twenty-one patients with serious infections involving anaerobic bacteria were treated with carbenicillin. multiple anaerobes were involved in 8 cases, and in 10 cases, facultative anaerobes were also isolated. bacteroides fragilis was isolated in 10 cases. results were judged excellent in 7 cases, good in 8 cases, and fair in 5 cases. these data suggest that carbenicillin may be an effective antibiotic for the therapy of infections due to anaerobic bacteria, particularly those involving b. fragi ...1976938020
human fecal flora: variation in bacterial composition within individuals and a possible effect of emotional stress.data are presented on the distribution of 101 bacterial species and subspecies among 1,442 isolates from 25 fecal specimens from three men on: (i) their normal diet and normal living conditions, (ii) normal living conditions but eating the controlled metabolic diet designed for use in the skylab simulation and missions, and (iii) the skylab diet in simulated skylab (isolation) conditions. these bacteria represent the most numerous kinds in the fecal flora. analyses of the kinds of bacteria from ...1976938032
chemical and biological characterization of the lipopolysaccharide of bacteroides fragilis subspecies fragilis.bacterial lipopolysaccharides extracted from bacteroides fragilis subspecies fragilis lacked 2-keto-3-deoxyoctonate and heptose, sugars which make up part of the inner core of most bacterial endotoxins. over 98% of the lipid portion of this material could be removed easily with chloroform-methanol and alcohol, a finding which indicates a loose association between the polysaccharide and lipid moieties. the lipopolysaccharides caused gelation of limulus lysate at a concentration significantly high ...1976939922
bacteroides fragilis ventriculitis and meningitis. report of two cases.two patients with bacteroides fragilis meningitis and ventriculitis were treated. in one infant infection developed at 2 1/2 months of age as a result of an infected ventriculoatrial shunt inserted to treat hydrocephalus. in the second patient ventriculitis and meningitis developed at 20 days of age, while he was convalescing from surgery for gastric perforation that had occurred at 5 days of age. both patients were treated with ampicillin, chloramphenicol, and clindamycin, which sterilized the ...1976941889
activity of sulfamethoxazole and trimethoprim against bacteroides fragilis.minimum inhibitory concentrations (mics) of sulfamethoxazole (smx) and trimethoprim (tmp), alone and in three combinations, 20:1, 1:1, and 1:20, were determined on diagnostic sensitivity test (dst) and mueller-hinton (mh) agars containing lysed blood for various inocula of 91 strains of bacteroides fragilis from the u.s.a. and u.k. mics of smx were high with large inocula and higher on mh than dst, but results for tmp were less affected by these two factors. true smx resistance was rare: 10 u.s. ...1976949171
activity of cefamandole and other cephalosporins against aerobic and anaerobic bacteria.the activity of cefamandole was comparable to that of cephalothin, cefazolin, and cephaloridine against staphylococcus aureus, streptococcus pyogenes, and diplococcus pneumoniae. in contrast, cefamandole was considerably more active than cephalothin, cefazolin, or cephaloridine against gram-negative facultative bacilli, including haemophilus influenzae, the most striking disparities being noted with indole-positive proteus and enterobacter. bacteroides fragilis was more susceptible to cefoxitin ...1976949182
in vitro susceptibilities of anaerobic bacteria to josamycin.a total of 132 strains of anaerobic bacteria were tested for susceptibility to josamycin, using a broth dilution technique. all strains of peptococcus species, peptostreptococcus species, and bacteroides fragilis were inhibited by 2 mug or less per ml. seventy percent of these susceptible strains were also killed by 2 mug or less of josamycin per ml. however, 2 of 12 clostridium species and 6 of 10 fusobacterium species had minimum inhibitory concentrations of 32 mug or more per ml.1976949184
serogrouping of bacteroides fragilis subsp. fragilis by the agglutination test.the agglutination technique was used to establish a serological classification scheme for 98 strains of bacteroides fragilis subsp. fragilis isolated from clinical specimens and normal human feces. absorbed antisera were prepared to seven strains of b. fragilis subsp. fragilis. these seven absorbed antisera were species as well as subspecies specific and provided the basis of the serological classification scheme. this scheme was composed of 21 serogroups; seven of these serogroups contained onl ...1976950378
letter: meningitis due to bacteriodes fragilis in a newborn infant. 1976952653
bacteroides fragilis and nitroimidazoles. 1976956086
vaginal flora in asymptomatic women.four groups of 25 asymptomatic women--pregnant, premenopausal and taking oral contraceptives, premenopausal and not taking oral contraceptives, and postmenopausal--were studied for the presence in vaginal specimens of aerobic bacteria, anaerobic bacteria, fungi, mycoplasma, chlamydia, herpes simplex virus, mycobacteria, and trichomonas. no significant differences in microbial flora were found among the groups.1976957791
anaerobic mediastinitis.three patients with anaerobic mediastinitis associated with retropharyngeal abscess have been encountered recently. dental infections accounted for two instances, and the third instance resulted from rupture of the thoracic esophagus from blunt trauma. each was marked by extreme difficulty in achieving complete abscess drainage due to the initially unrecognized virulence of the causative anaerobic bacteria. complications were frequent and included empyema, pericarditis and aspiration pneumonia. ...1976959954
[bacteroides infection in surgical patients (author's transl)].more than 80 cases of bacteroides infections are reported. 54 cases of these infections were postoperative complications. relationships between bacteroides infection and diseases of the colon are significant. not very impressive local symptoms made the diagnoses of abscesses difficult. in most cases bacteroides are susceptible to chloramphenicol and tetracycline. patients develop agglutinable antibodies after bacteroides infection.1976961145
purification of the o antigen of bacteroides fragilis ss. fragilis nctc 9343 from phenol-water extracts by gel filtration and chromatography on deae-cellulose and hydroxylapatite.o antigen extracted from whole cells of bacteroides fragilis ss. fragilis nctc 9343 with 45 per cent aqueous phenol has been purified by gel filtration and chromatography. first, the water phase was treated with rnase and dnase and passed through a column of agarose. the chromatographic procedures included ion exchange on a column of deae-cellulose and adsorption to hydroxylapatite. the o antigen was eluted from the deae-cellulose with a gradient of nacl, and from the column of hydroxylapatite w ...1976961434
faecal steroids and bacteria and large bowel cancer in hong kong by socio-economic groups.in a study of three socio-economic groups in hong kong, the high income group had a high faecal concentration of bile acids, especially the dihydroxy bile acids, compared to the low income group. the faecal bile acids were also more highly degraded. the faecal flora contained more bacteroides and fewer eubacteria. very few of the clostridia able to dehydrogenate the steroid nucleus were isolated. an epidemiological study based on street blocks indicated that the high income group also have a hig ...1976962996
use of semisolid agar from initiation of pure bacteroides fragilis infection in mice.the development of a pure bacteroides fragilis infection in mice is described. the infection produces large subcutaneous abscesses at the site of injection which can be observed grossly within 7 days after injection. the infection was initiated by infection of pure cultures grown in semisolid agar medium. similar infections were also produced with pure cultures of b. distasonis, b. ovatus, b. thetaiotaomicron, and b. vulgatus. however, a distinct deoxyribonucleic acid homology group, formerly cl ...1976965094
comparison of the in vitro bactericidal activity of human serum and leukocytes against bacteroides fragilis and fusobacterium mortiferum in aerobic and anaerobic environments.in aerobic and anaerobic in vitro environments, fusobacterium mortiferum was killed by human leukocytes or serum alone or in combination; clinical isolates of bacteroides fragilis were killed only by leukocytes in the presence of serum.1976965101
[bacteroides fragilis. its isolation and antibiotic sensitivity].the authors chose the problem of the isolation of bacteroides fragilis in pathological samples to present a method of identification of strict anaerobic gram negative bacteria, suitable for use in a routine bacteriological laboratory. a selection of 20 strains led them to study the mean inhibitory concentration of these germs with regard to antibiotics. from this study, two groups were obtained: one of low activity, the other of greater activity in vitro, in which one may note certain tetracycli ...1976970703
anaerobic infections in hospital practice.the role of anaerobes in the pathogenesis of infections was investigated. anaerobes were isolated from 0,25% of blood cultures and from 15,8% of other specimens tested; in 15,1% of cases where anaerobes were isolated, no aerobes were found. the strains most commonly encountered were bacteroides fragilis, b. melaninogenicus, peptostreptococcus anaerobius and clostridium perfringens. sensitivity tests in vitro showed all organisms to be sensitive to clindamycin, metronidazole and chloramphenicol, ...1976973160
[the significance of the bacterial steroid degradation for the etiology of large bowel cancer. v. transformation of chenodeoxycholic acid by saccharolytic bacteroides-species (author's transl)].we analysed a total of 36 strains of the obligately anaerobic bacteroides species b. vulgatus, b. fragilis, b. thetaiotaomicron, and b. distasonis to test their faculties to metabolize chenodeoxycholate. for experiments with growing cultures, we used a synthetic medium with inorganic salts, glucose, citrate, amino acids, vitamins, and hemin. the same medium, but without amino acids and vitamins was used for experiments with resting cells, incubated aerobically. after preincubation in a medium co ...1976983545
[the significance of the bacterial steroid degradation for the etiology of large bowel cancer. vi. degradation of deoxycholic acid by saccharolytic bacteroides-species (author's transl)].when testing 36 laboratory strains of the strictly anaerobic bacteroides species b. vulgatus, b. fragilis, b. thetaiotaomicron, and b. distasonis, we found activities for degradation of cholate (3alpha, 7alpha, 12alpha-trihydroxy-5 beta-cholanoate) (1) and chenodeoxycholate (3alpha, 7alpha-dihydroxy-5 beta-cholanoate) (2) widely, but not universally distributed in these bacteria. the same strains were also tested for their metabolic activities in regard to deoxycholate (3alpha, 12alpha-dihydroxy ...1976983546
beta-lactamase activity in anaerobic bacteria.a diverse group of anaerobic bacteria representing a spectrum of resistance to beta-lactam antibiotics was studied to characterize their beta-lactamase activity and relate it to resistance. the bacteroides fragilis organisms had moderate resistance and produced a cephalosporinase with low activity. the clostridium ramosum was intermediate in resistance and had intermediate, inducible beta-lactamase activity. the b. clostridiiformis organism was highly resistant, produced a potent inducible penic ...1976984742
susceptibility testing of anaerobic bacteria with 100-microg carbenicillin disks.a total of 245 strains of anaerobic bacteria were examined for their susceptibility to carbenicillin by the disk test method and by minimum inhibitory concentration (mic) determinations. standard-curve studies with a strain of bacteroides fragilis subsp. fragilis that was minimally susceptible to carbenicillin and escherichia coli (atcc 25922) demonstrated that a disk containing 100 mug of carbenicillin was suitable for testing susceptibility of anaerobes to carbenicillin. thus, the diameter of ...1976984743
in vitro activity of josamycin and rosamicin against bacteroides fragilis compared with clindamycin, erythromycin, and metronidazole.the inhibitory and bactericidal activities of josamycin and rosamicin against 29 clinical isolates of bacteroides fragilis were compared with those of clindamycin, erythromycin, and metronidazole by a broth dilution technique. josamycin and rosamicin had similar inhibitory activity to metronidazole and clindamycin. rosamicin had similar bactericidal activity to clindamycin but was less bactericidal than metronidazole (the most bactericidal agent tested). josamycin was slightly more bactericidal ...1976984752
in vitro activity of gentamicin and minocycline alone and in combination against bacteria associated with intra-abdominal sepsis.the minimal inhibitory concentrations of gentamicin and minocycline alone and in combination were determined by a broth microdilution method for 100 aerobic, facultative, and anaerobic isolates representative of pathogens recovered from patients with intra-abdominal sepsis. gentamicin inhibited all strains of klebsiella, enterobacter, and pseudomonas aeruginosa in concentrations of 0.4 to 3.1 mug/ml and all strains of escherichia coli and proteus mirabilis in concentrations of 0.8 to 12.5 mug/ml ...1976984755
in vitro susceptibility of common clinical anaerobic and aerobic isolates against josamycin.the in vitro susceptibility of 145 anaerobic clinical isolates and 96 gram-positive aerobic clinical isolates to josamycin, a new macrolide antibiotic, was studied using the agar dilution technique. ninety-five of the aerobes were susceptible to 1.56 mug or less of josamycin per ml. the median minimal inhibitory concentration of these organisms was </=0.39 mug/ml. the in vitro activity of josamycin against the anaerobes was compared with that of erythromycin, clindamycin, penicillin, and chloram ...1976984766
susceptibility of anaerobic bacteria to 23 antimicrobial agents.the antimicrobial susceptibility of 492 anaerobic bacteria, the majority of which were recent clinical isolates, was determined by the agar dilution technique. penicillin g was active against most of the strains tested at 32 u or less/ml, but only 72% of bacteroides fragilis strains were susceptible at this level and 9% required 256 u or more/ml. ampicillin was effective against most of the strains except b. fragilis at 16 mug or less/ml. amoxicillin was active against only 31% of b. fragilis, 7 ...1976984809
extrachromosomal elements in a variety of strains representing the bacteroides fragilis group of organisms.previous nucleic acid association studies have identified at least nine deoxyribonucleic acid (dna) homology classes of the bacteroides fragilis group of organisms. using these classes as a taxonomic framework, we have screened representative strains of the b. fragilis group for the presence of extrachromosomal (plasmid) dna. [3h]thymidine-labeled cell lysates were subjected to sodium dodecyl sulfate-salt precipitation, and supernatant fractions from such preparations were analyzed using cesium ...1976992876
effect of chilling on the survival of bacteroides fragilis.factors affecting the susceptibility of bacteroides fragilis subsp. fragilis to low temperature were examined. predetermined numbers of cells were spread on agar media or suspended in enriched trypticase soy broth and exposed to low temperature under both aerobic and anaerobic conditions. exposure of 18-h growth of a freshly isolated b. fragilis strain to 4 degrees c aerobically or anaerobically resulted in a loss of at least 50% viability after 12 h. b. fragilis cells in early growth (6 h) were ...1976993326
pelvic abscess. a sequela of first trimester abortion.first trimester therapeutic abortions were performed in 6790 patients from january 1, 1972, through december 31, 1973. the infectious morbidity during an 18-month concurrent time period which required readmission to the hospital was 0.52 per 100 women. four of these women were ultimately diagnosed as having a pelvic abscess thought to be related to the procedure. the cause was probably related to undiagnosed or inadequately managed uterine perforation. initial management should consist of system ...1976995342
[demonstration of agglutinating antibodies in bacteroides infections]. 1976997630
effect of dissolved oxygen and eh and bacteroides fragilis during continuous culture.bacteroides fragilis subsp. fragilis was maintained in a chemostat modified for anaerobic conditions to test the effects of dissolved oxygen and eh on growth. using a defined medium containing glucose and a dilution rate of 0.16 h -1, a stable population of 3 x 10(9) colony-forming units/ml was present. at this steady state, the ph was 5.6, the eh was -50 mv, and the dissolved oxygen concentration was 0% atmospheric saturation. the eh was then adjusted to +300 mv by adding potassium ferricyanide ...1976999270
clindamycin plus gentamicin as expectant therapy for presumed mixed infections.the prevalence of obligate anaerobes was studied prospectively in 60 patients with severe sepsis of intra-abdominal, soft tissue, female genital or oropulmonary origin. in addition, the efficacy of clindamycin (for anaerobes) plus gentamicin (for aerobic bacteria, especially coliforms) as initial empiric therapy in these patients was evaluated. among 54 patients with cultural proof of infection, anaerobic pathogens were recovered from 52%. nineteen patients had bacteremia; bacteroides fragilis a ...19761000457
histochemical studies on the effect of thyroid hormone on alkaline and acid phosphatase activities in liver of fish and amphibia.the lata fishes (ophicephalus punctatus) showed increased alkaline and acid phosphatase activities in liver after immersion for 15-30 days in thyroxine-containing medium (0.025 mug/ml). a single injection of thyroxine (1-2 mug/g of body weight) caused increased acid phosphatase activity in liver of lata fish in comparison to the controls on the 5th day after experiment but the alkaline phosphatase activity remained unchanged. both alkaline and acid phosphatases showed increased activities in liv ...19831001271
use of clindamycin and gentamicin in pediatric colonic surgery.the combination of clindamycin and gentamicin was used to treat 25 pediatric surgical patients. in 9 of the 11 patients with perforated appendicitis, b. fragilis was isolated from the peritoneal cavity. there was a rapid clinical response to treatment in all cases. no side effects were observed. clindamycin and gentamicin seem to be the antibiotics of choice for such infections.19761003306
[prolonged survival of ovarian allografts in rats pretreated with normal canine ribonucleic acid]. 19761004189
[cytogenetic effect of cyclophosphamide in a culture of human lymphocytes following its activation in the bodies of mice].cytogenetic effect of cyclophosphamide in cultured human lymphocytes after its activation in c57bl/6 mice in vivo was investigated. cyclophosphamide was injected intraperitoneally in mice for 30 min. at doses of 200, 400, 600, 800 and 1000 mg/kg. blood serum with activated metabolites of cyclophosphamide was added to human lymphocyte culture. the dependence of the part of aberrant metaphases on the concentration of cyclophosphamide after the activation can be presented as equation rho==1-e-(kc+a ...19761010318
a simple tube test for assessing antibiotic sensitivity of certain anaerobic bacteria. 19761032368
standardization of antimicrobial disc susceptibility test for anaerobic bacteria.both agar diluiton and agar diffusion tests with 8 clinically useful or potentially useful antimicrobial agents were performed with 74 strains of bacteroides fragilis. correlation of results obtained by the two methods and applicability of the single disc test to the measurement of antimicrobial susceptibility of anaerobes were analyzed. prediction of susceptibility, intermediate susceptibility, and resistance of anaerobic bacteria to antimicrobial agents, based on the measurement of inhibition ...19761037535
in vitro activity of penicillins against anaerobes.the in vitro susceptibility of 162 anaerobic isolates from clinical material were tested to pencillin g, bl-p1654, and carbenicillin. penicillin g and bl-p1654 showed good activity against bacteroides fragilis, but only 60% of strains were susceptible to carbenicillin at achievable blood levels (128 mug/ml).19751041215
in vivo protection of fusobacterium necrophorum from penicillin by bacteroides fragilis.a mixed infection of bacteroides fragilis and fusobacterium necrophorum was resistant to treatment with penicillin even though a pure f. necrophorum infection could be successfully treated with penicillin. since b. fragilis alone did not produce infection, these results indicate that b. fragilis can protect f. necrophorum from penicillin in vivo. the extent of protection afforded by a strain of b. fragilis was related to its level of resistance to penicillin. only a few cells of b. fragilis were ...19751041218
antimicrobial therapy of anaerobic infections. 19751041514
treatment of aspiration pneumonia and primary lung abscess. penicillin g vs clindamycin.aspiration pneumonitis and lung abscess generally involve anaerobic bacteria, which normally colonize the upper respiratory passages. the therapeutic response of these infections to parenteral penicillin g (49 patients) and parenteral clindamycin (35 patients) was compared to determine relative efficacy. no difference was discerned between these two agents in terms of time required for defervescence, roentgenographic clearing, and ultimate outcome. seven patients with infections including bacter ...19751041750
[letter: meningitis caused by bacteroides fragilis and mastoiditis caused by anaerobic bacteria after cranial injury]. 19761046166
pc-904, a novel broad-spectrum semisynthetic penicillin with marked antipseudomonal activity: microbiological evaluation.pc-904, sodium 6-{d(-)-alpha-(4-hydroxy-1,5-naphthyridine-3-carboxamido) phenylacetamido}-penicillanate, is a novel semisynthetic penicillin derivative that possesses a broad spectrum of in vitro and in vivo antibacterial activities. in low concentrations, pc-904 inhibits growth against large proportions of the gram-positive and gram-negative organisms susceptible to carbenicillin and gentamicin. in addition, pc-904 is several times more potent than carbenicillin against organisms such as pseudo ...19761046355
identification and antimicrobial susceptibility of 250 bacteriodes fragilis subspecies tested by broth microdilution methods.broth dilution antimicrobial susceptibility tests and biochemical identification of bacteroides fragilis subspecies were performed by micromethods, yielding results within 48 to 72 h of isolation. the subspecies had similar minimal inhibitory concentration end points.19761046357
the microdilution antibiotic susceptibility test. bacteroides fragilis.a micro broth-dilution method was developed for the antibiotic susceptibility testing of bacteroides frgilis. eighty strains of b. fragilis were tested against six antibiotics using the agar dilution test as the reference method. the microdilution test yielded results in 24 hours, and agreement with the reference test was satisfactory. certain subspecies-specific patterns of antibiotic susceptibility were observed. however, larger numbers of subspecies should be evaluated before subspeciation of ...19761047602
[a new flexible water-equivalent material (author's transl)]. 20051064001
the effect of main artery occlusion of one kidney on blood pressure of dogs.occluding the main artery of one kidney in each of six dogs resulted in an average increase in the renin concentration of the peripheral blood from the original 0.040 to 0.198 milliunit/ml of serum. during the same time (3-4 days), the occlusion also resulted in a significant rise of directly measured mean systemic blood pressure from an average basal level of 104 to 139 mm hg.19761064043
electrophoretic mobility of oral streptococci. 19761068652
national preventive dentistry program announced by afdh. 20041069080
the art of being convincing. 20051070362
when death necessitates selling a practice. 20051070377
transplantation behavior of a.th and a.tl t-cell lymphomas in congenic resistant and hybrid strains.seven spontaneously arising t-cell lymphomas originating in a.th or a.tl mice, which are congenic for the immune response gene (i) chromosomal segment were described. when transplanted into partner strains which were incompatible at the i region, the tumors were rapidly rejected. rejection was proposed to be due to the presence of antigens controlled by i-region genes.20051079852
[enzyme studies in rheumatic diseases]. 20051081257
new approach to caloric stimulation of the vestibular receptor.a new caloric testing method is described. during continuous aural irrigation, fluid is switched between hot and cold values at times computed according to a mathematical model of heat conduction in the labyrinth area. as a result, the induced temperature difference across the lateral semicircular canal describes an approximately sinusoidal time course, reaching peak values of equal magnitude but opposite sign. the magnitude of the caloric stimulus may be selected by choosing appropriate irrigat ...19751081359
pseudoxanthomatous mastocytosis.a case of xanthelasmoidea (pseudoxanthomatous mastocytosis) occurring in a 50-year-old iranian man is described. the patient had a large upper gastrointestinal haemorrhage.19751081401
the differentiation of cytotoxic t lymphocytes in vitro: an ultrastructural study.t killer cells were identified morphologically in two different culture systems. the first system allowed identification by comparing under identical culture conditions two types of stimulation, one leading to cytotoxic activity levels that were very high (h-2 stimulation) and the other to levels which were practically nil (m-locus stimulation). a second system allowed identification by the use of a collaborative system in which relatively pure precursors of t killer cells were mixed with precur ...20051082798
[acute renal failure: disorders of calcium regulation]. 20051087428
[non-invasive diagnosis of occlusive disease of the carotid arteries]. 20051087432
ontogeny of thymus factor secretion.the circulating thymic factor (tf) detected by 0-conversion assay has been followed up in ontogeny. serum tf evaluation in pregnant thymectomized mice and in new born mice indicates that tf secretion starts on day 12-13 of foetal life and has reached the adult's level at birth.20051087546
bimodal action of glycine on frog spinal motoneurones.in the presence of procaine the changes in electrical potential caused by glycine in the ventral root of the isolated hemisected spinal cord of the frog have been shown to be compounded of both hyperpolarizing and depolarizing responses to the amino acid. from a comparison of the effects of changes in the perfusion medium on the potentials produced by glycine, beta-alanine and l-glutamate in the presence and absence of strychnine, it was concluded that glycine acts on a similar receptor to beta- ...20051087578
[a case of ameloblastoma of the maxilla (author's transl)]. 20051087664
in vitro interaction of bacteroides fragilis with polymorphonuclear leukocytes and serum factors.the sera and polymorphonuclear leukocytes (pmns) of healthy human subjects were tested against several isolates of bacteroides fragilis. all sera killed most of the fecal isolates, but were active aganist only one of the clinical isolates. the degree of killing was directly related to the serum concentration but was independent of the bacterial inoculum within the range of bacterial concentrations studied. the serum bactericidal activity was heat-labile. engulfment and killing of b. fragilis by ...19751089602
erythrocyte polyagglutination showing properties of both t and tk, probably induced by bacteroides fragilis infection.a new type of polyagglutination is described in which the t and tk receptors are both exposed on the erythrocyte membrane. it is suggested that there may be an association between this type of polyagglutination and infection by bacteroides fragilis.19751092064
wound infections due to bacteroides fragilis following intestinal surgery.ninety-six wound infections due to bacteroides fragilis occurring after intestinal surgery are described. most infections followed appendicectomy or colectomy for diverticulitis. b. fragilis was isolated in pure growth from 47 per cent of infections, and in mixed culture the other common bacteria were klebsiella spp., escherichia coli and enterobacter spp. fifty-three per cent of the infections responded rapidly to either non-specific measures or antibiotic therapy, but 47 per cent of patients d ...19751095111
comparative in vitro acitvity of chloramphenicol and thiamphenicol on common aerobic and anaerobic gram-negative bacilli(salmonella and shigella excluded).the antibacterial activity of thiamphenicol was compared to that of chloramphenicol against 313 strains of gram-negative bacilli isolated from various clinical specimens. these two antiboitics were equally active against the 106 isolates of haemophilus mic equals 0.1 minus 1.56 mu g/ml) and against 40 strains of bacteroides fragilis (almost all strains being inhibited by 12.5 mug/ml of the two drugs). in contrast, when compared with chloramphenicol, 2-16 times as much of thiamphenicol was requir ...19751097209
treatment with metronidazole of three patients with serious infections due to bacteroides fragilis. 19751100592
isolation of plasmid deoxyribonucleic acid from two strains of bacteroides.two clinical isolates of bacteroides contained covalently closed circular deoxyribonucleic acid (dna) as shown by sedimentation in an alkaline sucrose gradient, cscl ethidium bromide equilibrium centrifugation, and electron microscopy. bacteriodes fragilis n1175 contained a homogeneous species of plasmid dna with a molecular weight of 25 x 10(6). bacteroides ochraceus 2228 contained two distinct, covalently closed circular dna elements. the larger cosedimented with the covalently closed circular ...19751100611
arthritis associated with intestinal-bypass procedure for morbid obesity. complement activation and characterization of circulating cryoproteins.five patients were studied after intestinal-bypass operations for morbid obesity to determine if the arthritis observed in three of these patients was associated with circulating cryoproteins. only serum from the three patients with acute arthritis contained cryoprotein complexes. the complexes comprised igg, igm, iga, complement components c3, c4, c5 and igg antibody against escherichia coli and bacillus fragilis. the c3-activator fragment of the properdin complex was identified in fresh serum ...19761105187
significance of anaerobic bacteria isolated from the urinary tract. ii. experimental studies.an attempt to cause retrograde urinary tract infection with bacteroides fragilis (a strain subcultured in artificial media) failed to produce any significant renal infection in rats. intravenous inoculation with fusobacterium (a strain subcultured in artificial media) also did not cause demonstrable renal infection in rats. nor could the anaerobic organism be demonstrated in the kidneys of these animals. animals receiving bacteroides (a strain subcultured in artificial media) inoculated directly ...19761107257
a simple method for rapid isolation and identification of bacteroides fragilis. 19751108844
the impact of laboratory error on the normal range: a bayesian model.interpretation of clinical laboratory results, aside from clinical considerations, is based on the probability of the result being within a given normal range. this probability is influenced by the degree of error inherent in the analytical method. it would be advantageous to assign a more definite probability to the result of the measurement by combining the error distribution of the result around the true value and the distribution of the healthy population that serves as a reference. bayesian ...20051112041
from the files of the kma maternal mortality study committee. 19981113024
bacteriophage-associated spherical bodies in bacteroides fragilis.unique spherical bodies with multilayered walls were observed by electron microscopy in cells of a single strain of bacteroides fragilis subsp. fragilis. phage-like particles were present in the same cells, both free in the cytoplasm and within the spheres. the proportion of cells containing the phage-associated spherical structures ranged from less than 0.01% to about 7% depending on the culture conditions. phage particles of morphological type b and spherical bodies were also found free in the ...19751117488
bacteroides: a cause of residual abscess?bacteroides fragilis as a cause of residual abscess has not been previously demonstrated. this clinical and bacteriologic study of 54 consecutive cases of appendectomy in children suggests that if b. fragilis is found in the peritoneal fluid at the time of operation there is a strong possibility of residual abscess development. special collection and culture methods are necessary to obtain positive cultures of this strictly anaerobic organism.19751123703
effects of time and growth media on short-chain fatty acid production by bacteroides fragilis.gas-liquid chromatography was used to monitor the evolution of short chain fatty acids by bacteroides fragilis in five media. acetic and succinic acids, the prominent end products encountered, were readily detected within 24 h. propionic, isobutyric, isovaleric, and lactic acids were usually recorded in more limited quantities. maximum rates of bacterial multiplication, glucose catabolism, and end-production coincided with the first 24 h in carbohydrate-supplemented media. extended incubation (6 ...19751124920
tryptophanase of fecal flora as a possible factor in the etiology of colon cancer.twenty-three strains of intestinal anaerobes obtained from two laboratories were examined for indole production from tryptophan. among the 23 isolates tested, three of bacteroides fragilis thetaiotaomicron and one citrobacter sp. were indole positive. the tryptophanase of the indole-positive strains of intestinal anaerobes was inducible by tryptophan and was susceptible to glucose repression. the products of tryptophanase activity were formed in stoichiometric amounts by dialyzed, freshly prepar ...19751127736
[letter: value of metronidazole in septicemia caused by bacteroides fragilis. 2 cases]. 19751129130
[our therapeutic approach to the puerperal mastitis (author's transl)]. 20051131902
the minimum effective amount of uncouplers for rat liver mitochondria. 19751132494
[aspects of the surgical treatment of utero-vaginal prolapse]. 20051134682
geriatric patient care. opinions of a sample of nurses. 20051134987
comparative susceptibility of anaerobic bacteria to minocycline, doxycycline, and tetracycline.the comparative susceptibility of 622 recent clinical isolates of anaerobic bacteria to minocycline, doxycycline, and tetracycline was determined by an agar-dilution technique. in addition to bacteroides fragilis, a variety of other anaerobic bacteria was resistant to achievable blood concentrations of tetracycline (55% inhibited by 6.25 mug/ml) and doxycycline (58% inhibited by 2.5 mug/ml). in contrast, minocycline was significantly more active (p < 0.05) than both doxycycline and tetracycline, ...19751137358
susceptibility of anaerobes to cefoxitin and other cephalosporins.the in vitro susceptibility of 155 strains of anaerobic bacteria to five cephalosporin antibiotics was tested. cefoxitin was the most active against 33 isolates of bacteroides fragilis; 82% of the strains were sensitive at 16 mug/ml. at 64 mug/ml cefazolin and cephaloridine were also generally effective. cephalothin and cephalexin were relatively inactive versus b. fragilis. cefoxitin, cephaloridine, cefazolin, and cephalothin showed comparable activity against 122 strains of anaerobes other tha ...19751137364
fertility in relation to red cell potassium types in murrah buffaloes. 20051140495
travel to work. 19871140968
[a bacteriological investigation of norwegian cod liver oil (author's transl)].samples of medicinal cod liver oil collected from four of the main producers in norway have been investigated for content of microorganism. viable counts for bacteria and fungi were found to be low. no coliform bacteria, coagulase positive staphylococcus or pseudomonas could be detected. the findings suggest that the main part of the flora found in cod liver oil belongs to the family micrococcaceae. several of the isolated colonies showed lipolytic activity.19751144018
[blood serum content of fucose and neutral hexoses in patients with acute viral hepatitis]. 19781145296
[study of pancreatic exocrine function under the effect of stimulation with increased doses of secretin. ductal cellular mass and secretory capacity]. 19781145454
[problems of renal dysfunction in chronic renal insufficiency]. 19781145488
[bacterial endocarditis in patients kept on regular hemodialysis]. 19781145489
letter: retroperitoneal paraganglioma. 19791145918
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