Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| evidence for mycoplasma ssp., chlamydia pneunomiae, and human herpes virus-6 coinfections in the blood of patients with autistic spectrum disorders. | we examined the blood of 48 patients from central and southern california diagnosed with autistic spectrum disorders (asd) by using forensic polymerase chain reaction and found that a large subset (28/48 or 58.3%) of patients showed evidence of mycoplasma spp. infections compared with two of 45 (4.7%) age-matched control subjects (odds ratio = 13.8, p < 0.001). because asd patients have a high prevalence of one or more mycoplasma spp. and sometimes show evidence of infections with chlamydia pneu ... | 2007 | 17265454 |
| hiv/aids diagnoses among blacks--florida, 1999-2004. | in 2004, florida accounted for 11% of the total number of acquired immunodeficiency syndrome (aids) cases in the united states, ranking third behind new york and california. florida also had the second-highest reported aids diagnosis rate (behind new york). during 2004, non-hispanic blacks accounted for 14% of the florida population but 52% of the 77,421 persons in florida living with human immunodeficiency virus (hiv)/aids. this report describes trends in diagnoses of hiv/aids cases that occurr ... | 2007 | 17268403 |
| molecular characterization of a variant rhinovirus from an outbreak associated with uncommonly high mortality. | human rhinoviruses (hrvs) are the most frequent cause of acute upper respiratory tract infection, however, they are also known to replicate in the lower respiratory tract and associate with more severe respiratory illnesses. an outbreak of hrv occurred in a long-term facility in santa cruz, california with unusually high morbidity and mortality. | 2007 | 17276135 |
| trends in the use of sexually transmitted disease diagnostic technologies in california, 1996-2003. | to describe trends in std diagnostic test volume and test technology in california from 1996 to 2003. | 2007 | 17277611 |
| major fetal abnormalities associated with positive screening tests for smith-lemli-opitz syndrome (slos). | determine the relationship between positive screening interpretations for smith-lemli-opitz syndrome (slos) and other fetal abnormalities, to aid counseling and diagnostic activities. | 2007 | 17286308 |
| detection of rickettsia rickettsii and bartonella henselae in rhipicephalus sanguineus ticks from california. | sixty-two questing adult rhipicephalus sanguineus (latreille) ticks were collected by direct removal from blades of turfgrass and adjacent concrete walkways at a suburban home in riverside county, ca, and tested for the presence of rickettsia, bartonella, and ehrlichia dna. polymerase chain reaction (pcr) was used to amplify fragments of the 17-kda antigen gene and the rompa gene of the spotted fever group rickettsiae. one male tick contained r. rickettsii dna; its genotype differed from r. rick ... | 2007 | 17294935 |
| transcription factor 7-like 2 (tcf7l2) is associated with gestational diabetes mellitus and interacts with adiposity to alter insulin secretion in mexican americans. | variation in transcription factor 7-like 2 (tcf7l2) gene has been shown to be associated with type 2 diabetes and diabetes-related quantitative traits. we examined variation in a 0.1-mb region surrounding marker dg10s478 for association with diabetes-related quantitative traits in 132 mexican-american families of a proband with previous gestational diabetes mellitus (gdm). | 2007 | 17317761 |
| management by assertion: beavers and songbirds at lake skinner (riverside county, california). | management of ecological reserve lands should rely on the best available science to achieve the goal of biodiversity conservation. "adaptive resource management" is the current template to ensure that management decisions are reasoned and that decisions increase understanding of the system being managed. in systems with little human disturbance, certain management decisions are clear; steps to protect native species usually include the removal of invasive species. in highly modified systems, how ... | 2007 | 17318698 |
| proprietary rights in body parts: the relevance of moore's case in australia. | 1993 | 17333577 | |
| performance-based measures: the early results are in. | pay for performance (p4p) initiatives are designed to foster and reward improvement in health care delivery. these programs promote "value-based health care" by rewarding quality care that is characterized by a reduced amount of disproportionate spending. | 2007 | 17341139 |
| coccidioides niches and habitat parameters in the southwestern united states: a matter of scale. | to determine habitat attributes and processes suitable for the growth of coccidioides, soils were collected from sites in arizona, california, and utah where coccidioides is known to have been present. humans or animals or both have been infected by coccidioides at all of the sites. soil variables considered in the upper 20 cm of the soil profile included ph, electrical conductivity, salinity, selected anions, texture, mineralogy, vegetation types and density, and the overall geomorphologic and ... | 2007 | 17344527 |
| the public health need and present status of a vaccine for the prevention of coccidioidomycosis. | although the epidemiology of coccidioidomycosis has been well described, there is a paucity of recent data on the public health burden associated with this disease. accordingly, california's inpatient hospital discharge data set from 1997 to 2002 was used to calculate the incidence of hospitalization for coccidioidomycosis by county, year, age, race, ethnicity, and gender. the overall finding that coccidioidomycosis has a significant impact in endemic areas supports the conclusion that the need ... | 2007 | 17344529 |
| association between cfl1 gene polymorphisms and spina bifida risk in a california population. | cfl1 encodes human non-muscle cofilin (n-cofilin), which is an actin-depolymerizing factor and is essential in cytokinesis, endocytosis, and in the development of all embryonic tissues. cfl1 knockout mice exhibit failure of neural tube closure at e10.5 and die in utero. we hypothesized that genetic variation within the human cfl1 gene may alter the protein's function and result in defective actin depolymerizing and cellular activity during neural tube closure. such alterations may be associated ... | 2007 | 17352815 |
| comparative in vitro toxicity of grape- and citrus-farm dusts. | agricultural workers are exposed to a variety of airborne dusts, including crystalline silica and other inorganic minerals. this study was designed to characterize the organic and inorganic components of agricultural dusts in california grape- and citrus-farm fields and to compare their cytotoxicity using in vitro toxicity bioassays as predictors of pathogenicity. aerosolized dusts collected from farm fields were characterized by scanning-electron-microscopic energy-dispersive x-ray analysis, x- ... | 2007 | 17365569 |
| polybrominated diphenyl ether levels in the blood of pregnant women living in an agricultural community in california. | recent studies have raised concerns about polybrominated diphenyl ether (pbde) flame retardant exposures to pregnant women and women of child-bearing age in the united states. few studies have measured pbdes in immigrant populations. | 2007 | 17366822 |
| u.s.: sexual history must be disclosed in lawsuit for negligent hiv transmission, california supreme court rules. | in july 2006, the supreme court of california ruled that a man being sued for allegedly transmitting hiv to his partner was required to disclose information about his sexual history. the court also decided that in order to sue for negligent transmission of hiv, a plaintiff need not prove that the defendant actually knew he was hiv-positive at the time of sexual relations. rather, it would be enough for the plaintiff to show that the defendant had reason to know he was living with hiv at the time ... | 2006 | 17373084 |
| multiple antimicrobial resistance in plague: an emerging public health risk. | antimicrobial resistance in yersinia pestis is rare, yet constitutes a significant international public health and biodefense threat. in 1995, the first multidrug resistant (mdr) isolate of y. pestis (strain ip275) was identified, and was shown to contain a self-transmissible plasmid (pip1202) that conferred resistance to many of the antimicrobials recommended for plague treatment and prophylaxis. comparative analysis of the dna sequence of y. pestis plasmid pip1202 revealed a near identical inc ... | 2007 | 17375195 |
| telesurgery via unmanned aerial vehicle (uav) with a field deployable surgical robot. | robotically assisted surgery stands to further revolutionize the medical field and provide patients with more effective healthcare. most robotically assisted surgeries are teleoperated from the surgeon console to the patient where both ends of the system are located in the operating room. the challenge of surgical teleoperation across a long distance was already demonstrated through a wired communication network in 2001. new development has shifted towards deploying a surgical robot system in mo ... | 2007 | 17377292 |
| america's changing attitudes toward homosexuality, civil unions, and same-gender marriage: 1977-2004. | on may 17, 2004, massachusetts became the first state to legalize same-gender marriage. from california to missouri, nearly all states now face legislative challenges to the once firmly entrenched notion that marriage can only exist between a man and a woman. public opinion polls conducted from 1977 to 2004 found that americans' attitudes toward gay men and lesbians and marriages or civil unions for same-gender couples have evolved. opposition persists, however. the most recent data indicate sup ... | 2007 | 17388085 |
| a comparison of ozone exposure in fresno and shaver lake, california. | ground-level ozone is a pollutant that has been found to have detrimental effects on plants as well as in humans. few studies, however, have measured ozone exposure in mountainous regions downwind from highly polluted urban centers, despite the popularity of these regions as summer destinations. the study reported here evaluated ozone levels in fresno, california, and the downwind community of shaver lake, california, during the summer months of june, july, and august from 1997 to 2001. findings ... | 2007 | 17390901 |
| expanding understanding of epidemiology of coccidioidomycosis in the western hemisphere. | coccidioidomycosis is a disease of both national and worldwide importance that is most often diagnosed in nonendemic regions. the endemic region for coccidioides spp. lies exclusively in the western hemisphere. coccidioides spp. has long been identified in semiarid areas of the united states and mexico, and endemic foci have been described in areas of central and south america. infection is usually the result of activities that cause the fungus to become airborne and inhaled by a susceptible hos ... | 2007 | 17395731 |
| chagas disease in the united states: a cause for concern in louisiana? | chagas disease, or american trypanosomiasis, is an arthropod-borne protozoan infectious disease, hyperendemic throughout latin america, caused by trypanosoma cruzi, and transmitted to man by reduviid or kissing bugs. throughout the americas, chagas disease shares many life cycle features with malaria, including transmission of infectious stages by local arthropods, exacerbation or reactivation of subclinical infections by immunosuppression (particularly hiv/aids) and pregnancy, and both transpla ... | 2007 | 17396472 |
| herpes simplex virus type 2 infection does not influence viral dynamics during early hiv-1 infection. | we sought to compare baseline and longitudinal plasma hiv-1 loads between herpes simplex virus type 2 (hsv-2)-seropositive and -seronegative individuals who are enrolled in a primary hiv-1 infection cohort in san diego, california. | 2007 | 17396995 |
| market basket survey shows elevated levels of as in south central u.s. processed rice compared to california: consequences for human dietary exposure. | we report the largest market basket survey of arsenic (as) in u.s. rice to date. our findings show differences in transitional-metal levels between polished and unpolished rice and geographical variation in as and selenium (se) between rice processed in california and the south central u.s. the mean and median as grain levels for the south central u.s. were 0.30 and 0.27 mimcrog as g(-1), respectively, for 107 samples. levels for california were 41% lower than the south central u.s., with a mean ... | 2007 | 17438760 |
| human rabies--indiana and california, 2006. | rabies is a viral infection that causes acute, progressive encephalitis and is considered to be universally fatal. however, during 2004, an unvaccinated wisconsin patient received a new medical treatment and became the first documented survivor of rabies who had not received preexposure vaccination or postexposure prophylaxis (pep), suggesting the possibility of successful future interventions. this report describes two recent patients with rabies who were treated using therapy similar to that u ... | 2007 | 17443120 |
| polychlorinated biphenyls (pcbs) in san francisco bay. | san francisco bay is facing a legacy of polychlorinated biphenyls (pcbs) spread widely across the land surface of the watershed, mixed deep into the sediment of the bay, and contaminating the bay food web to a degree that poses health risks to humans and wildlife. in response to this persistent problem, water quality managers are establishing a pcb total maximum daily load (tmdl) and implementation plan to accelerate the recovery of the bay from decades of pcb contamination. this article provide ... | 2007 | 17451673 |
| theregen, inc. | theregen, inc. is a regenerative medicine company based in san francisco, california, usa, that develops cell-based therapies for patients with cardiovascular and vascular disease. the company is conducting a phase i human clinical safety trial at two us sites for its lead product, anginera, a cell-based epicardial patch therapy. anginera is designed to promote blood vessel growth in damaged cardiac tissue, stimulate wound healing and, potentially, to restore cardiac function in patients with he ... | 2006 | 17465766 |
| human immunodeficiency virus and hepatitis c virus testing services at syringe exchange programs: availability and outcomes. | we described the availability and outcomes of human immunodeficiency virus (hiv) and hepatitis c virus (hcv) testing services at syringe exchange programs throughout california, using interviews with 24 syringe exchange program directors and 560 syringe exchange clients. both hiv and hcv testing services were available in 62% of programs, 21% had hiv testing only, and 17% had neither. programs administered by health care/social service providers were more likely than independent syringe exchange ... | 2007 | 17481466 |
| responsible oversight of human stem cell research: the california institute for regenerative medicine's medical and ethical standards. | 2007 | 17488179 | |
| muscle markers revisited: activity pattern reconstruction with controls in a central california amerind population. | anthropologists frequently use musculoskeletal stress markers to reconstruct past activity patterns. yet, researchers have called into question the reliability of muscle marker measurements in part because body size and age affect muscle marker scores. in this study, the author examined an aggregate upper limb muscle marker to determine if after controlling for the effects of body size and age, one could reconstruct activity patterns of a prehistoric amerind population. analyses were made of a s ... | 2007 | 17492666 |
| direct and indirect costs of rabies exposure: a retrospective study in southern california (1998-2002). | the direct and indirect costs of suspected human rabies exposure were estimated for san luis obispo and santa barbara counties, california, usa. clinic, hospital, and county public health records (1998-2002) were examined to determine direct costs for postexposure prophylaxis (pep), and 55 (41%) former patients were contacted to voluntarily provide estimates of their indirect costs associated with receiving pep. additional costs due to public health and animal control personnel responses to rabi ... | 2007 | 17495309 |
| on the experience of epilepsy. | 2007 | 17502558 | |
| some limitations of aggregate exposure metrics. | aggregate exposure metrics based on sums or weighted averages of component exposures are widely used in risk assessments of complex mixtures, such as asbestos-associated dusts and fibers. allowed exposure levels based on total particle or fiber counts and estimated ambient concentrations of such mixtures may be used to make costly risk-management decisions intended to protect human health and to remediate hazardous environments. we show that, in general, aggregate exposure information alone may ... | 2007 | 17511710 |
| racial misidentification of american indians/alaska natives in the hiv/aids reporting systems of five states and one urban health jurisdiction, u.s., 1984-2002. | we examined racial misidentification of american indians/alaska natives (ai/an) reported to the human immunodeficiency virus (hiv)/acquired immunodeficiency syndrome (aids) reporting systems (hars) of five u.s. states and one county. | 2007 | 17518310 |
| merging models and biomonitoring data to characterize sources and pathways of human exposure to organophosphorus pesticides in the salinas valley of california. | we characterize cumulative intakes of organophosphorus (op) pesticides in an agricultural region of california by drawing on human biomonitoring data, california pesticide use reporting (pur) data, and limited environmental samples together with outputs from the caltox multimedia, multipathway, source-to-dose model. the study population is the chamacos cohort of almost 600 pregnant latina women in the salinas valley region. we use model estimates of op intake and urinary dialkylphosphate (dap) m ... | 2007 | 17539531 |
| hcv and hiv counseling and testing integration in california: an innovative approach to increase hiv counseling and testing rates. | in california, injection drug users (idus) comprise the second leading risk group for human immunodeficiency virus (hiv) infection and the majority of hepatitis c virus (hcv) cases. innovative disease screening and prevention activities are needed to improve disease surveillance and to guide appropriate public health responses. this study tested the hypothesis that offering hiv counseling and testing (c&t) concurrently with hcv c&t will increase hiv c&t rates among idus. | 2007 | 17542457 |
| mixture modeling of transcript abundance classes in natural populations. | populations diverge in genotype and phenotype under the influence of such evolutionary processes as genetic drift, mutation accumulation, and natural selection. because genotype maps onto phenotype by way of transcription, it is of interest to evaluate how these evolutionary factors influence the structure of variation at the level of transcription. here, we explore the distributions of cis-acting and trans-acting factors and their relative contributions to expression of transcripts that exhibit ... | 2007 | 17547747 |
| "no compensation" or "pro compensation": moore v. regents and default rules for human tissue donations. | the much studied case of moore v. regents of the university of california is often considered important in property law for denying property rights in human tissue. this widespread misunderstanding of moore has not only misplaced the legal emphasis of human tissue donations on property law instead of contract law, but has also hindered the creation of a much-needed default rule governing the issue of compensation for donated tissue. while it is possible that the majority of donors rarely conside ... | 2007 | 17549930 |
| prisons. hiv-positive man denied free counsel over health care claim. | 2007 | 17552076 | |
| comparing public discourses in stem cell policy debates. | public policy debates surrounding stem cell research are becoming increasingly more complex as governance considerations move beyond the moral status of human embryos. this complexity is evident in the public discourses surrounding these debates globally. this article draws on the results of an analysis conducted on the media coverage of a recent stem cell policy episode in the united states to demonstrate the complexity of public discourses surrounding stem cell research and to reflect upon sim ... | 2007 | 17571787 |
| rapid hiv testing in emergency departments--three u.s. sites, january 2005-march 2006. | approximately one fourth of the estimated 1 million persons living with human immunodeficiency virus (hiv) in the united states are unaware that they are infected with hiv and at risk for transmitting the virus to others. in april 2003, cdc announced a new initiative, advancing hiv prevention: new strategies for a changing epidemic, aimed at reducing barriers to early diagnosis of hiv infection and increasing access of persons infected with hiv to medical care and prevention services. a priority ... | 2007 | 17585288 |
| microbial source tracking in a small southern california urban watershed indicates wild animals and growth as the source of fecal bacteria. | three independent microbial source tracking (mst) methods were applied to a small urban subwatershed in orange county, california. fifty-seven water samples collected over summer 2002 were analyzed for human adenovirus and enterovirus. enterococci and e. coli were isolated for antibiotic resistance analysis (ara) and for pcr identification of human- and animal-specific toxin genes, respectively. all water samples were pcr negative for human enteroviruses and e. coli human-specific toxin gene. e. ... | 2007 | 17589839 |
| the identity, distribution, and impacts of non-native apple snails in the continental united states. | since the mid 1990s populations of non-native apple snails (ampullariidae) have been discovered with increasing frequency in the continental united states. given the dramatic effects that introduced apple snails have had on both natural habitats and agricultural areas in southeast asia, their introduction to the mainland u.s. is cause for concern. we combine phylogenetic analyses of mtdna sequences with examination of introduced populations and museum collections to clarify the identities, intro ... | 2007 | 17594487 |
| epigenetic and mitochondrial mechanisms in aging and longevity: a report of a meeting of the longevity consortium, napa, california, october 25-27, 2006. | 2007 | 17595412 | |
| symptomatic early neurosyphilis among hiv-positive men who have sex with men--four cities, united states, january 2002-june 2004. | symptomatic early neurosyphilis is a rare manifestation of syphilis that usually occurs within the first 12 months of infection. most neurologic symptoms of early neurosyphilis result from acute or subacute meningitis, abnormalities in cranial nerve function, and inflammatory vasculitis leading to a cerebrovascular accident. symptomatic early neurosyphilis essentially disappeared in the united states after the introduction of penicillin treatment for syphilis in the late 1940s but reappeared in ... | 2007 | 17597693 |
| the first 'molecular disease': a story of linus pauling, the intellectual patron. | in november 1949, chemist linus pauling and three colleagues published an article on sickle-cell anemia, a study that opened up new and exciting possibilities for research into such 'molecular diseases'. even before this celebrated publication appeared in science, pauling foresaw its potential benefits and announced it as a medical breakthrough: '... our structural chemistry and understanding of molecules is getting to the point where it should be of assistance in converting medicine into a real ... | 2007 | 17602747 |
| brailer resigns from hhs panel. decision comes on heels of his firm's calpers deal. | 2007 | 17608112 | |
| a randomised controlled trial evaluating an alternative mouse and forearm support on upper body discomfort and musculoskeletal disorders among engineers. | the aim of this intervention study was to determine the effects of an alternative mouse and/or a forearm support board on the change in upper body discomfort scores and the development of incident musculoskeletal disorders. | 2008 | 17626135 |
| molecular quantitative analysis of human viruses in california stormwater. | many human pathogenic viruses are transmitted via the oral-fecal route and water is one possible vector, representing a risk for public health. sixty-one large-volume water samples from storm drains in california were processed by a two-step hollow fiber ultrafiltration procedure followed by molecular analysis for human enterovirus and adenovirus types. each sample was spiked with a surrogate, the benign bacteriophage pp7. both surrogate and human viruses were quantified by newly designed taqman ... | 2007 | 17628629 |
| vertebrate hosts of ixodes pacificus (acari: ixodidae) in california. | the western black-legged tick, ixodes pacificus cooley & kohls, is an important parasite and vector of disease agents that affect human and animal health in the western united states. this paper presents a review of all published california host records for i. pacificus. unpublished data from public health, academic, and vector control agencies and researchers were reviewed as well. host species were identified for each active life stage (larvae, nymph and adult). a total of 108 vertebrate speci ... | 2007 | 17633435 |
| frequent occurrence of the human-specific bacteroides fecal marker at an open coast marine beach: relationship to waves, tides and traditional indicators. | molecular genetic markers, such as those from fecal bacteroides microorganisms, can link microbial pollution with its source, and have been used successfully in studies of sheltered aquatic environments. their applicability to wave-driven, open coast environments has not been tested. we assessed the contribution of a tidal outlet to surf zone water quality in coastal orange county, california, usa by measuring three traditional culture-based fecal indicator bacteria (fib) as well as the human-sp ... | 2007 | 17635548 |
| metal content of the gulf of california blue shrimp litopenaeus stylirostris (stimpson). | the blue shrimp litopenaeus stylirostris is the main target species of the gulf of california shrimping fleet, and its heavy metal content might be of concern for human health because of the increasing contamination of the gulf. the cd content of shrimp caught by commercial trawlers ranged from 0.38 to 1.05 microg/g and the mean value was significantly lower in the northern fishing grounds. pb ranged from 3.19 to 9.59 microg/g and was significantly higher in the northern area. there were no sign ... | 2007 | 17639322 |
| the tidal influence on oil and gas emissions from an abandoned oil well: nearshore summerland, california. | oil and gas emissions were quantified for natural and human sources in nearshore waters off summerland, california through deployment of custom designed collection tents. seepage was measured at a repeatedly abandoned well, on the seabed from a caisson located along the historical location of the treadwell wharf, where the world's first off-shore oil wells were drilled at the end of the 19th century. seepage rates at the capped t-10 well, located in approximately 5m water, showed high correlatio ... | 2007 | 17640686 |
| dean of death row: the man who became the face of san quentin. | 2007 | 17650579 | |
| heterosexual anal sex among female drug users: u.s. national compared to local long beach, california data. | receptive anal sex is a well-studied human immunodeficiency virus (hiv) high-risk behavior among gay and bisexual men, yet previous research indicates that more women than men may be at risk from heterosexual anal sex (has). 1991-1996 data from the national institute on drug abuse (nida) cooperative agreement (ca) were analyzed to model risk for women who reported having had has in the 30 days prior to interview. this model was then tested on recent data (2001-2006) collected on women in long be ... | 2008 | 17653843 |
| clinical and genetic risk factors for pneumonia in systemic lupus erythematosus. | to define the contribution of polymorphisms in genes encoding tumor necrosis factor (tnf), mannose-binding lectin (mbl), and fcgamma receptor iia (fcgr2a) as well as clinical factors, to the development of pneumonia in patients with systemic lupus erythematosus (sle). | 2007 | 17665457 |
| frequent transmission of immunodeficiency viruses among bobcats and pumas. | with the exception of human immunodeficiency virus (hiv), which emerged in humans after cross-species transmissions of simian immunodeficiency viruses from nonhuman primates, immunodeficiency viruses of the family lentiviridae represent species-specific viruses that rarely cross species barriers to infect new hosts. among the felidae, numerous immunodeficiency-like lentiviruses have been documented, but only a few cross-species transmissions have been recorded, and these have not been perpetuate ... | 2007 | 17670835 |
| environmental tobacco smoke and bladder cancer risk in never smokers of los angeles county. | cigarette smoking is a major risk factor for bladder cancer and a prominent point source of 4-aminobiphenyl (4-abp), a recognized human bladder carcinogen. 4-abp-hemoglobin (hb) adducts are established biomarkers of 4-abp exposure in humans. the role of environmental tobacco smoke (ets) in the etiology of bladder cancer is largely unknown. as part of a large population-based bladder cancer study in los angeles county, california, lifetime exposure to ets was ascertained for 148 cases and 292 con ... | 2007 | 17671226 |
| a summer outbreak of human metapneumovirus infection in a long-term-care facility. | human metapneumovirus (hmpv), a recently discovered paramyxovirus, is thought to be primarily a winter-spring pathogen affecting young children with a clinical presentation similar to that of respiratory syncytial virus. in june-july 2006, a respiratory outbreak in a long-term-care facility was reported to the local health department and investigated. surveillance identified 26 residents and 13 staff with acute respiratory illness; 8 residents (31%) developed radiographically confirmed pneumonia ... | 2007 | 17674312 |
| quantitation in gated perfusion spect imaging: the cedars-sinai approach. | cedars-sinai's approach to the automation of gated perfusion single photon emission computed tomography (spect) imaging is based on the identification of key procedural steps (processing, quantitation, reporting), each of which is then implemented, in completely automated fashion, by use of mathematic algorithms and logical rules combined into expert systems. our current suite of software applications has been designed to be platform- and operating system-independent, and every algorithm is base ... | 2007 | 17679052 |
| essential and toxic metals in nine fish species for human consumption from two coastal lagoons in the eastern gulf of california. | with the aim of knowing concentrations of cd, cu, fe, mn, pb and zn; percentage of daily mineral intake (pmi) for essential elements and percentage of weekly intake (pwi) of toxic metals in commercial fish from 2 coastal lagoons in the eastern gulf of california, analyses were carried out in 9 species. highest values of cd were detected in the liver of the sharks sphyrna lewini and carcharhinus leucas, pb was mostly detected in the liver of s. lewini; cu and mn in the liver and gills of the mull ... | 2007 | 17680479 |
| xenobiotic metabolizing enzyme gene polymorphisms predict response to lung volume reduction surgery. | in the national emphysema treatment trial (nett), marked variability in response to lung volume reduction surgery (lvrs) was observed. we sought to identify genetic differences which may explain some of this variability. | 2007 | 17686149 |
| population genetics of the frog-killing fungus batrachochytrium dendrobatidis. | global amphibian decline by chytridiomycosis is a major environmental disaster that has been attributed to either recent fungal spread or environmental change that promotes disease. here, we present a population genetic comparison of batrachochytrium dendrobatidis isolates from an intensively studied region of frog decline, the sierra nevada of california. in support of a novel pathogen, we find low diversity, no amphibian-host specificity, little correlation between fungal genotype and geograph ... | 2007 | 17693553 |
| beach sands along the california coast are diffuse sources of fecal bacteria to coastal waters. | fecal indicator bacteria (fib) are nearly ubiquitous in california (ca) beach sands. sands were collected from 55 beaches along the ca coast. ninety-one percent of the beaches had detectable enterococci (ent) while 62% had detectable e. coli (ec) in their sands. the presence of a putative bacterial source (such as a river), the degree of wave shelter, and surrounding land use explained a significant (p < 0.05) fraction of the variation in both ent and ec densities between beaches. sand character ... | 2007 | 17695890 |
| rabies surveillance in the united states during 2006. | during 2006, 49 states and puerto rico reported 6,940 cases of rabies in animals and 3 cases in humans to the cdc, representing an 8.2% increase from the 6,417 cases in animals and 1 case in a human reported in 2005. approximately 92% of the cases were in wildlife, and 8% were in domestic animals. relative contributions by the major animal groups were as follows: 2,615 raccoons (37.7%), 1,692 bats (24.4%), 1,494 skunks (21.5%), 427 foxes (6.2%), 318 cats (4.6%), 82 cattle (1.2%), and 79 dogs (1. ... | 2007 | 17696853 |
| pet ownership and blood pressure in old age. | it has been proposed that pet ownership improves cardiovascular health. this study examines the relation of pet ownership with systolic and diastolic blood pressure, pulse pressure, mean arterial pressure, and hypertension in a large sample of older men and women. | 2007 | 17700250 |
| human influence on california fire regimes. | periodic wildfire maintains the integrity and species composition of many ecosystems, including the mediterranean-climate shrublands of california. however, human activities alter natural fire regimes, which can lead to cascading ecological effects. increased human ignitions at the wildland-urban interface (wui) have recently gained attention, but fire activity and risk are typically estimated using only biophysical variables. our goal was to determine how humans influence fire in california and ... | 2007 | 17708216 |
| paradoxical ozone associations could be due to methyl nitrite from combustion of methyl ethers or esters in engine fuels. | we review studies of the effects of low ambient ozone concentrations on morbidity that found a negative coefficient for ozone concentration. we call this a paradoxical ozone association (poa). all studies were in regions with methyl ether in gasoline. all but one study carefully controlled for the effects of other criterion pollutants, so the phenomenon cannot be attributed to them. one was in southern california in mid-summer when ozone levels are highest. because ozone is created by sunlight, ... | 2007 | 17716731 |
| variations in adh and aldh in southwest california indians. | native americans as a group have the highest rates of alcohol-related deaths of all ethnicities in the united states; however, it remains unclear how and why a greater proportion of individuals in some native american communities develop alcohol-related problems and alcohol use disorders (auds). one potential factor that can influence responses to alcohol are variations in alcohol-metabolizing enzymes. researchers have analyzed the frequencies of variants in the alcohol-metabolizing enzymes alco ... | 2007 | 17718395 |
| seasonal detection of human viruses and coliphage in newport bay, california. | recent studies have shown that the fecal indicator bacteria (fib) currently used to indicate water quality in the coastal environment may be inadequate to reflect human viral contamination. coliphage was suggested as a better indicator of human viral pollution and was proposed by the u.s. epa as an alternative indicator for fecal pollution in groundwater. in this study, we investigated the occurrence and distribution of fib, f+ coliphage, and pcr-detectable human adenovirus and enterovirus for a ... | 2007 | 17720839 |
| amplified fragment length polymorphism analysis of mycobacterium avium complex isolates recovered from southern california. | fine-scale genotyping methods are necessary in order to identify possible sources of human exposure to opportunistic pathogens belonging to the mycobacterium avium complex (mac). in this study, amplified fragment length polymorphism (aflp) analysis was evaluated for fingerprinting 159 patient and environmental mac isolates from southern california. aflp analysis accurately identified strains belonging to m. avium and mycobacterium intracellulare and differentiated between strains within each spe ... | 2007 | 17761476 |
| initial experiences with subcutaneous recombinant human hyaluronidase. | we report here our retrospective observations on the use of recombinant human hyaluronidase (rhuph20) for the facilitation of subcutaneous hydration and drug infusion. thirty-two patients were treated with rhuph20 in a hospice setting over a 6-month period. of these, 26 received this agent to enhance hypodermoclysis with standard hydration fluids for symptom control of delirium, myoclonus and mild to moderate dehydration. flow rates up to 500 ml/hr were attained without difficulty. electrolyte r ... | 2007 | 17803404 |
| depuration of polybrominated diphenyl ethers (pbdes) and polychlorinated biphenyls (pcbs) in breast milk from california first-time mothers (primiparae). | little is known about the rates of loss (depuration) of polybrominated diphenyl ethers (pbdes) and polychlorinated biphenyls (pcbs) from mothers during lactation. depuration rates affect infant exposure to chemicals during breast-feeding, and fetal and lactational transfers during subsequent pregnancies. | 2007 | 17805415 |
| pillbox organizers are associated with improved adherence to hiv antiretroviral therapy and viral suppression: a marginal structural model analysis. | pillbox organizers are inexpensive and easily used; however, their effect on adherence to antiretroviral medications is unknown. | 2007 | 17806060 |
| endemic human mosquito-borne disease in wisconsin residents, 2002-2006. | west nile virus (wnv) and la crosse virus (lac) are the primary mosquito-borne arboviruses associated with human disease in wisconsin. we examined wnv and lac human illness surveillance data collected during 2002 through 2006. | 2007 | 17844707 |
| nutrient intakes in women and risks of anophthalmia and microphthalmia in their offspring. | there is a paucity of information about risk factors for the human eye anomalies anophthalmia and microphthalmia. in this population-based case-control study we investigated whether periconceptional intakes of supplemental folic acid, dietary folate, vitamin a, and several other nutrients were associated with these eye defects. | 2007 | 17847120 |
| a conversation with arthur kavanaugh. | biologic therapies play a greater role in the treatment of human autoimmune diseases than they did in the past. arthur kavanaugh, md, professor of clinical medicine, university of california, san diego, school of medicine, talked with managed care interface about the use of these agents, ongoing research in this area, and genetic factors that can come into play when treating rheumatoid arthritis. | 2007 | 17849730 |
| public reporting and pay-for-performance: safety-net hospital executives' concerns and policy suggestions. | safety-net hospitals (snhs) may gain little financial benefit from the rapidly spreading adoption of public reporting and pay-for-performance, but may feel compelled to participate (and bear the costs of data collection) to meet public expectations of transparency and accountability. to better understand the concerns that snh administrators have regarding public reporting and pay-for-performance, we interviewed 37 executives at randomly selected california snhs. the main concerns noted by snh ex ... | 2007 | 17850040 |
| socioeconomic gradients in immune response to latent infection. | there is a strong relation between socioeconomic position and health outcomes, although the mechanisms are poorly understood. the authors used data from 1,503 california participants in the 1998-1999 sacramento area latino study on aging aged 60-100 years to ask whether socioeconomic position is related to immune function as measured by the body's ability to keep latent herpesvirus antibody levels in a quiescent state. individuals with lower educational levels had significantly higher levels of ... | 2008 | 17873099 |
| john l. horn (1928-2006). | john leonard horn was born in st. joseph, missouri, on september 7, 1928, and he died in los angeles, california, on august 18, 2006. john horn was a world-renowned scholar of immense intellect, and he was highly respected in his time. i believe his major contributions to psychology, as well as his influence on psychologists, will continue to grow. his challenging factor-analytic methods of the 1960s, the important methodological debates of the 1970s and 1980s, and his continuing resistance to f ... | 2007 | 17874900 |
| history-adjusted marginal structural models for estimating time-varying effect modification. | much of epidemiology and clinical medicine is focused on estimating the effects of treatments or interventions administered over time. in such settings of longitudinal treatment, time-dependent confounding is often an important source of bias. marginal structural models (msms) are a powerful tool for estimating the causal effect of a treatment using observational data, particularly when time-dependent confounding is present. in recent statistical work, van der laan et al. presented a generalized ... | 2007 | 17875580 |
| representational fluency in hiv clinical practice: a model of instructor discourse. | clinicians treating human immunodeficiency virus (hiv) patients are expected to stay up-to-date with rapidly changing knowledge and practice. continuing medical education (cme) programs are one source of new knowledge about hiv clinical management. little is known about instructor-participant discourse in hiv cme programs and whether or how instructors model their decision-making strategies. | 2007 | 17876845 |
| creating a model program for influenza surveillance in california: results from the 2005-2006 influenza season. | influenza surveillance is valuable for monitoring trends in influenza-related morbidity and mortality. using the 2005-2006 influenza season as an example, this paper describes a comprehensive influenza surveillance program used by the california department of public health (cdph). | 2007 | 17888862 |
| as the raven flies: using genetic data to infer the history of invasive common raven (corvus corax) populations in the mojave desert. | common raven (corvus corax) populations in mojave desert regions of southern california and nevada have increased dramatically over the past five decades. this growth has been attributed to increased human development in the region, as ravens have a commensal relationship with humans and feed extensively at landfills and on road-killed wildlife. ravens, as a partially subsidized predator, also represent a problem for native desert wildlife, in particular threatened desert tortoises (gopherus aga ... | 2008 | 17908216 |
| effects of anthropogenic developments on common raven nesting biology in the west mojave desert. | subsidized predators may affect prey abundance, distribution, and demography. common ravens (corvus corax) are anthropogenically subsidized throughout their range and, in the mojave desert, have increased in number dramatically over the last 3-4 decades. human-provided food resources are thought to be important drivers of raven population growth, but human developments add other features as well, such as nesting platforms. from 1996 to 2000, we examined the nesting ecology of ravens in the mojav ... | 2007 | 17913134 |
| optical information for car following: the driving by visual angle (dva) model. | the present study developed and tested a model of car following by human drivers. | 2007 | 17915604 |
| sustainability. this man wants to green your lab. | 2007 | 17916705 | |
| cost-effectiveness of adding human papilloma virus testing to a managed care cervical cancer screening program. | the purpose of this study was to demonstrate a methodology for auditing the impact of hcii testing on the direct cost of cervical cancer cytological screening, where the test is collected in all women screened and processed routinely in women age 30 years and older. | 2007 | 17917570 |
| club drug use in los angeles among young men who have sex with men. | little is known about young men who have sex with men's use of club drugs and the risk factors associated with such use. a structured survey was administered in 2005 to 496 young men who were 18-22 years old (40% were 18-19 years old); self-identified as with a same-sex sexuality (83%), bisexual (16%), and/or had had sex with a man (97%); caucasian (35%), african american (24%), and latino of mexican descent (40%). subjects were recruited from gay-identified venues in los angeles, california, us ... | 2007 | 17934992 |
| the human-canine environment: a risk factor for non-play bites? | few dog bite risk factor studies have been conducted. this veterinary clinic-based retrospective cohort study was aimed at identifying human-canine environmental risk factors for non-play bites in kingston, jamaica (660) and san francisco (sf), usa (452). data were analysed using modified poisson regression with confounders selected using directed acyclic graphs (dags) and the change-in-estimate procedure. dogs acquired for companionship were more likely (rr=1.66; 95% ci 1.02-2.70) to bite than ... | 2008 | 17937998 |
| associations between prenatal exposure to polychlorinated biphenyls and neonatal thyroid-stimulating hormone levels in a mexican-american population, salinas valley, california. | studies have reported that prenatal exposure to polychlorinated biphenyls (pcbs) may alter neurodevelopment in both humans and animals. furthermore, prenatal exposure to some pcb congeners and commercial mixtures has been shown to decrease free and total thyroxine (t(4)) blood levels in animals. because thyroid hormones (th) are essential for normal neurologic development, it has been suggested that the deleterious neurodevelopmental effect of pcbs may occur through th disruption. pcbs may in tu ... | 2007 | 17938741 |
| comparison of direct immunofluorescence, immunoassays, and fecal flotation for detection of cryptosporidium spp. and giardia spp. in naturally exposed cats in 4 northern california animal shelters. | giardia spp. and cryptosporidium spp. are common intestinal protozoan parasites in domestic cats. few studies have critically evaluated the performance characteristics of commercially available immunoassays for detection of these organisms in the cat. | 2007 | 17939549 |
| the outdoor air quality flag program in central california: a school-based educational intervention to potentially help reduce children's exposure to environmental asthma triggers. | this paper describes a novel school-based, visual environmental public health educational intervention intended to help reduce the exposure of children-and adults-to outdoor air pollution, including known environmental asthma triggers like ozone and particles. the overarching goal was to enhance the learning, recreational, and work environments of students and staff. the specific purpose of the asthma-friendly outdoor (ambient) air quality flag program was to establish an education and communica ... | 2007 | 17941400 |
| reduction of injuries associated with patient handling. | nurses experience more back injuries than the general population due to their physically demanding work. research indicates that the implementation of a comprehensive patient-handling program will reduce the number of patient-handling injuries and associated sequelae. a significant barrier to the effectiveness of safe patient-handling programs includes lack of appropriate and easily accessible equipment for caregivers. caregivers were questioned to identify changes in the use of and perceptions ... | 2007 | 17969538 |
| recruiting low-income healthy women to research: an exploratory study. | the study goals were (1) to assess the feasibility of using an existing telephone health information and referral service for low-income, ethnically diverse women to recruit women for research participation; (2) to assess the feasibility of recruiting low-income, african american and latino men into health research through the women callers to the telephone service; and (3) to describe the challenges women face and the strategies they use when talking to men about the men's health and research p ... | 2007 | 17978946 |
| human papilloma virus immunization in adolescent and young adults: a cohort study to illustrate what events might be mistaken for adverse reactions. | the large-scale implementation of human papilloma virus (hpv) immunization will be followed by cases of autoimmune diseases occurring in temporal association with immunizations. to anticipate events that might be mistakenly assumed to be caused by immunization, their prevalence was monitored before vaccine introduction. | 2007 | 17984802 |
| building an infrastructure to prevent falls in older californians: the fall prevention center of excellence. | the fall prevention center of excellence (center), a consortium of federal, state, and private organizations, was established in 2005 to guide the implementation of a statewide initiative to prevent falls among older californians. the process began with the convening of a representative group of recognized leaders in california's health and human services in 2003. this group engaged in a 2-day strategic planning process that culminated in the development of the california blueprint for fall prev ... | 2007 | 17986582 |
| origin, occurrence, and source emission rate of acrolein in residential indoor air. | acrolein, a volatile, unsaturated aldehyde, is a known respiratory toxicant and one of the 188 most hazardous air pollutants identified by the u.s. epa. a newly developed analytical method was used to determine residential indoor air concentrations of acrolein and other volatile aldehydes in nine homes located in three california counties (los angeles, placer, yolo). average indoor air concentrations of acrolein were an order of magnitude higher than outdoor concentrations at the same time. all ... | 2007 | 17993132 |
| thermal desorption comprehensive two-dimensional gas chromatography for in-situ measurements of organic aerosols. | the complexity of organic composition and temporal variability of atmospheric aerosols presents an extreme analytical challenge. comprehensive two-dimensional gas chromatography (gc x gc) has been used on time integrated filter samples to reveal the presence of thousands of individual organic compounds in aerosols, but without defining the temporal variability in composition ideal for providing information on source resolution and human exposure to specific pollutants. we hereby introduce a new ... | 2008 | 18001751 |
| evaluation and application of the rd50 for determining acceptable exposure levels of airborne sensory irritants for the general public. | the rd(50) (exposure concentration producing a 50% respiratory rate decrease) test evaluates airborne chemicals for sensory irritation and has become an american society for testing and materials (astm) standard method. past studies reported good correlations (r(2)) between rd(50)s and the occupational exposure limits, particularly threshold limit values (tlvs). | 2007 | 18007993 |