Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| quantitative assessment of free gingival grafts with and without periosteum and osseous perforation. | forty free gingival grafts were performed on 5 adult rhesus monkeys as follows: 10 grafts were placed on recipient sites with periosteum; 10 grafts on periosteum and perforated cortical plate; 10 grafts on bared bone; and 10 grafts on perforated bared bone. all free autografts (7 x 5 x 1 mm) were taken from the palatal mucosa and were sutured in place. clinical evaluation and photographs were taken at 1, 2, 4, 8, 12, 16, 20 and 24 weeks postoperatively. at 24 weeks, a device was used to measure ... | 1978 | 413900 |
| continuous intravenous naltrexone effects on morphine self-administration in rhesus monkeys. | rhesus monkeys, surgically prepared with intravenous catheters, were given opportunities to self-administer morphine for 3 days, methamphetamine for 2 days and saline for 2 days in a constantly repeating cycle. access to drugs was limited to a 15-minute period every 4 hours. after stable base-line self-administration rates, saline or various concentrations of naltrexone were infused continuously through the catheter. in the first phase of the study each concentration of naltrexone was infused fo ... | 1978 | 413904 |
| synthesis and analgetic activity of 1,2,3,4,5,6-hexahydro-1,6-methano-3-benzozocines. | 1,2,3,4,5,6-hexahydro-1,6-methano-3-benzazocine (1) has been synthesized via a four-step sequence from benzo-norbornadiene. this compound and its n-methyl derivative are more active than codeine in the mouse hot-plate antinociceptive assay and will not suppor morphine dependence in rhesus monkeys. | 1978 | 413922 |
| induction of monooxygenases in rhesus monkeys by 3-methylcholanthrene: metabolism and mutagenic activation of n-2-acetylaminofluorene and benzo(a)pyrene. | induction of content and activity of hepatic and lung cytochrome p450-dependent monooxygenases by 3-methylcholanthrene (mca) was studied in male rhesus monkeys. hepatic microsomes were concomitantly studied for mutagenic activation of n-2-acetylaminofluorene (aaf) as well as with the use of sodium dodecyl sulfate-polyacrylamide gel electrophoresis. hepatic n-hydroxylation of aaf was increased sixfold to sevenfold after mca treatment; aryl hydrocarbon hydroxylase was similarly increased in both l ... | 1978 | 413928 |
| incorporation of (3h) lysine into the brain and spinal cord of the cebus (cebus appella) and rhesus (macacca mulata) monkeys. | the relative amounts of incorporation of [3h] lysine into various brain areas and segments of the spinal cord in adult cebus and rhesus monkeys were studied. one hour after subcutaneous injection of [3h] lysine, animals were sacrificed and the brain and spinal cord samples taken and processed for [3h] lysine incorporation into protein (lowry et al., 1951; wells and bernstein, 1976). analysis revealed marked differences in metabolism among brain areas within each species of monkey as well as acro ... | 1977 | 413933 |
| thoracic duct cannulation of the rhesus monkey (macaca mulatta) for lymphocyte collection: thoracic approach. | the thoracic duct of the rhesus monkey (macaca mulatta) was cannulated with medical grade tubing through a thoracatomy at right interspace 9-10. in 42 monkeys successfully cannulated, a mean of 1.194 x 10(9) lymphocytes was collected in the 70-hour period after surgery. a second collection, 1-3 weeks later, was possible for a shorter period (up to 60 hours) in a portion of these monkeys (15) with a smaller mean yield of lymphocytes (1.076 x 10(9). a third, but still shorter, collection period of ... | 1977 | 414020 |
| lumbar puncture for obtaining cerebrospinal fluid in the rhesus monkey (macaca mulatta). | 1977 | 414022 | |
| identification of hemoglobins within individual rhesus monkey (macaca mulatta) erythrocytes. | rabbit and goat antibodies to monkey adult and fetal hemoglobin were prepared and purified to apparent monospecificity. after conjugation with fluorescein isothiocyanate, the antibodies were employed to identify the hemoglobin types within individual cells in peripheral erythrocyte smears. the percentage of neonatal monkey erythrocytes containing fetal hemoglobin was found to decrease with time. the existence of adult or fetal hemoglobin in the erythrocytes appeared to be mutually exclusive. | 1977 | 414023 |
| measurement of hemolytic complement and the third component of complement in nonhuman primates. | complement, determined by hemolytic assay, and the third component of complement (c3), determined by radial immunodiffusion assay, were measured in nine nonhuman primate species. the species studied were the titi (callicebus mollach). the sooty mangabey (cercocebus atys), the thick-tailed galago or bushbaby (galago crassicaudatus panganiensis), the crab-eating monkey (macaca fascicularis), the rhesus monkey (macaca mulatta), the bonnet monkey (macaca radiata), the stumptailed macaque (macaca spe ... | 1977 | 414024 |
| conspecific images as elements of compound stimuli controlling operant responding in female rhesus monkeys. | six adult female rhesus monkeys (macaca mulatta) performed food-reinforced button presses in a compound stimulus discrimination paradigm. three subjects were trained on a compound stimulus consisting of a color motion picture of an adult male rhesus superimposed over a homogeneous blue field of color. a second group of three subjects was trained on a compound consisting of a color slide depicting an adult male rhesus and the blue field. subsequent testing of relative stimulus control exerted by ... | 1977 | 414197 |
| the effects of hypotension and hypovolaemia on the liberation of vasopressin during haemorrhage in the unanaesthetized monkey (macaca mulatta). | using unanaesthetized monkeys, experiments were performed to examine the effects of haemorrhage on the liberation of arginine vasopressin (avp). haemorrhages of 10%, 15% or 20% total blood volume were performed via a catheter with its tip in the abdominal vena cava. a catheter in the left internal jugular vein was used for blood sampling. arterial blood pressure was monitored via a catheter whose tip resected in an iliac artery. the monkeys showed no signs of discomfort from this catheterisation ... | 1977 | 414200 |
| regulation of appetite during total parenteral nutrition. | to study effects of total parenteral nutrition (tpn) on appetite, in an effort to obtain an objective assessment of hunger separated from underlying pathology, caloric intake and levels of tpn were measured in two male rhesus monkeys. tpn was found to affect appetite by reducing voluntary food intake. one monkey showed precise regulation of daily oral caloric intake and maintained stable body weight during this period. the other monkey did not show such precise regulation. when tpn was stopped, ... | 1978 | 414211 |
| effects of clomipramine and other inhibitors of monoamine uptake on the sexual behaviour of female rats and rhesus monkeys. | 1977 | 414218 | |
| cholesterol and hormone levels in sera of juvenile female rhesus monkeys. | 1978 | 414237 | |
| changes in testosterone and behavior during adolescence in the male rhesus monkey. | five adolescent male rhesus were followed for 3 years, from age 2 through age 4, with the collection of monthly testosterone levels, along with observation of behavior. testosterone levels showed initial rises by age 3, but did not show the adult male seasonal pattern until 4. play behavior fell significantly from age 2 to age 3, while sex behavior showed seasonal increases in both year 2 and year prior to the rise in plasma testosterone. the number of adult males in the social group may influen ... | 1978 | 414289 |
| development and evaluation of a new water-soluble iodinated myelographic contrast medium with markedly reduced convulsive effects. | a new water-soluble myelographic contrast agent with more hydrophilic properties than metrizamide was developed and tested in the primate (macaca mulatta) and the cat. a new animal model that allows study of the convulsive effects of intrathecally administered contrast agents in the awake monkey was designed. with this sensitive model the new contrast agent was shown to have a remarkable reduced convulsive effect when compared with metrizamide and other media. intrathecal hypertonic solutions in ... | 1978 | 414304 |
| the hypothalamic regulation of lh and fsh secretion in the rhesus monkey. | 1978 | 414314 | |
| measurement of regional substrate utilization rates by emission tomography. | emission tomography can be used to monitor, in vivo and regionally, the utilization of metabolic substrates labeled with positron-emitting radioisotopes produced by a cyclotron. the concept was validated by measuring brain glucose utilization with carbon--11-labeled glucose in rhesus monkeys. | 1978 | 414358 |
| [antibodies in rhesus-monkeys after experimental infection with african lung-worms (paragonimus uterobilateralis and p. africanus) (author's transl)]. | the following publication gives a report about serological studies on experimentally infected macaca mulatta with paragonimus uterobilateralis and p. africanus supplied by parasitological findings and chest x-ray experiments from other authors. it was shown that at first in the chronological sequence serological changes were noticed in the animals followed by x-ray changes of the lungs. somewhat later the monkeys started with the excretion of worm-eggs. egg production did not take place in all m ... | 1977 | 414393 |
| the metabolism of ftorafur in the beagle dog and rhesus monkey. | 1. ftorafur, a fluorinated pyrimidine nucleoside antimetabolite, is metabolized by the beagle dog and rhesus monkey to 5-fluorouracil, which is subsequently biotransformed to the corresponding nucleosides, to alpha-fluoro-beta-ureidopropionic acid, to urea and to co2. 2. in the dog, urea was the primary urinary metabolite while in the monkey, alpha-fluoro-beta-ureidopropionic acid predominated. 3. the dog and monkey excrete about 35 percent of the recovered dose as co2. 4. the possibility that f ... | 1977 | 414463 |
| evaluation of central nervous adaptability to low stress and high stress categories in rhesus monkeys by multivariate evoked potential analyses [proceedings]. | 1977 | 414507 | |
| histological analysis of the growth of the mandibular condyle in the rhesus monkey (macaca mulatta). | 1978 | 414614 | |
| effects of androgen administration on sexual invitations by female rhesus monkeys (macaca mulatta). | pairs of adult rhesus monkeys of opposite sexes (12 pairs) were studied during 1-h mating tests (986 tests). ovariectomized females received 5 microgram oestradiol intravaginally throughout to keep them attractive to males and maintain a relatively constant level of male sexual activity. females were given subcutaneous silastic implants of testosterone to change their sexual receptivity. a threefold change in sexual invitations resulted from the implantation and removal of testosterone in the ab ... | 1977 | 414641 |
| effects of immunisation on dental caries in the first permanent molars in rhesus monkeys. | 1977 | 414700 | |
| empirical model of intracranial pressure and head motion resulting from a vibrating seated rhesus. | a series of experiments was designed to measure the head x and z accelerations and the intracranial pressure in the unrestrained head of a rhesus monkey. the subject was exposed to a continuum of vibration frequencies from 2 to 35 hz and peak acceleration amplitudes of 5, 10, 20, and 40 m/s2. the resulting data was used to build a frequency response model relating the head accelerations and pressures to the torso acceleration. the head-to-torso relationships, based upon a single subject, were bo ... | 1978 | 414728 |
| conjugated and unconjugated bilirubins in bile of humans and rhesus monkeys. structure of adult human and rhesus-monkey bilirubins compared with dog bilirubins. | 1. bilirubin-ixalpha, -ixalpha diglucuronide, -ixalpha monoglucuronide, -ixalpha monoglucoside -ixalpha monoxyloside, a bilirubin-ixalpha diconjugate containing glucose and another unknown compound, and bilirubin-ixbeta are present in gall-bladder bile of adult human, rhesus monkey and dog. dog bile normally also contains other bilirubin-ixalpha diconjugates, i.e. compounds containing two conjugating sugars such as glucuronic acid and glucose, glucuronic acid and xylose and glucose xylose. 2. az ... | 1977 | 414741 |
| the development of pyruvate dehydrogenase in the subhuman primate macaca mulatta. | the development of total pyruvate dehydrogenase activity in the subhuman primate, macaca mulatta, was investigated in brain, liver, kidney cortex, and skeletal and cardiac muscle. newborn primates delivered prematurely at 135 days of gestation had only 32% of this enzyme activity present in the brain compared to the full-term animal. full-term animals were similar to adults. all tissues showed high activities of enzyme at 1 year of age compared either with neonates or adults. kidney cortex showe ... | 1977 | 414794 |
| patch-like termination of thalamic fibers in the putamen of the rhesus monkey: an autoradiographic study. | 1978 | 414821 | |
| heterosexual, autosexual and social behavior of adult male rhesus monkeys with medial preoptic-anterior hypothalamic lesions. | bilateral radiofrequency lesions were made in the medial preoptic-anterior hypothalamic (mp-ah) area of 6 adult male rhesus monkeys; 5 sham-lesioned subjects served as controls. behavioral analysis consisted of observations on copulatory behavior, yawning, masturbation and some aspects of social behavior. mp-ah lesions reduced or completely eliminated the display of manual contacts of the partner, mounts, intromissions and ejaculations without interfering with masturbation. yawning, a sexually d ... | 1978 | 414825 |
| comparison of the convulsant effects of cocaine and pseudococaine in the rhesus monkey. | the convulsant effects of cocaine and its c2-epimer, pseudococaine on eeg, respiration, heart rate and behavior were studied in the rhesus monkeys with electrodes implanted in the brain. intravenous injections of cocaine (3.0 to 8.0 mg/kg) and pseudococaine (3.0 to 7.0 mg/kg) in the animals produced a similar pattern of clonic convulsions accompanied by marked increases in the heart and respiratory rates with mydriasis and excessive salivation. however, both isomers showed different effects on t ... | 1977 | 414826 |
| harmonic analysis of the left ventricular pressure waveform of the primate. | most attempts to quantitate myocardial function rely on morphologic features of complex pressure waveforms to reflect the functional properties of the ventricular myocardium. relationships between waveform components and the function of the organ generating them were examined in 38 rhesus monkeys by harmonic analysis of left ventricular pressure waveforms. in the basal state, harmonic content was closely correlated (r=0.98) with hemodynamic state, as quantitated by heart rate, systolic and diast ... | 1978 | 414837 |
| induction of hapten-specific cell-mediated immunity in rhesus monkeys treated with adsorbent purified antilymphocyte antibody. | rhesus monkeys were treated with sufficient amounts of rabbit antilymphocyte sera and immunoadsorbent purified antilymphocyte antibody to retain full-thickness skin grafts 23 and 29 days respectively. during this immunosuppressed period hapten-specific cell-mediated immunity was induced in six of seven rhesus monkeys immunized with p-azophenylarsono-n-acetyltyrosine (r-tyr) in complete freund's adjuvant. these observations suggest that in rhesus monkeys different populations of t cells may be re ... | 1977 | 414990 |
| antibody mediated mechanisms of immunity to malaria induced by vaccination with plasmodium knowlesi merozoites. | rhesus monkeys vaccinated with merozoites in fca are protected against challenge with several strains and variants of plasmodium knowlesi. vaccination induces sterilizing immunity which is species specific. merozoite-blocking (inhibitory) antibody usually correlates with clinical immunity and protection can be passively transferred with immune sera provided these contain high levels of inhibitory antibody. however, vaccination using adjuvants other than fca may induce inhibitory antibody without ... | 1978 | 414993 |
| regional differences in the metabolism of testosterone in vitro in the epididymis & ductus deferens of the adult rhesus monkey macaca mulatta. | regional differences in the metabolism of testosterone in vitro in the epididymis (1.5 cm segments) and ductus deferens (2 cm segments) were investigated in the adult rhesus monkey, macaca mulatta. the conversion of tritiated testosterone to its 5alpha-reduced derivatives increased from the proximal to the distal regions of the epididymis. the total amount of 5alpha-reduced products in the subsequent segments of the epididymis was highest in the intact monkey and on the intact side of the unil ... | 1977 | 414995 |
| histochemical localization of dehydrogenases in different regions of the epididymis of the adult rhesus monkey macaca mulatta. | 1977 | 414996 | |
| histochemical distribution of metabolites & lipolytic enzymes in different regions of the epididymis of the adult rhesus monkey macaca mulatta. | 1977 | 414997 | |
| mammalian cones: disc shedding, phagocytosis, and renewal. | during the past several years we have examined a variety of different mammalian retinas for ultrastructural evidence of cone disc shedding and rpe phagocytosis. in this paper we review our previously published evidence from squirrel and human retinas as well as present new evidence of cone disc shedding in rhesus monkey and cat. all these species show definitive evidence for the shedding of discs from cone outer segments and the phagocytosis of shed discs by apical processes of the rpe; both of ... | 1978 | 415019 |
| accuracy of aqueous humor flow determination by fluorophotometry. | after corneal iontophoresis of fluorescein, freshly enucleated rhesus monkey eyes were perfused at a known rate with glutathione-bicarbonate-ringer's solution. total fluorescein mass and aqueous fluorescein concentration were measured with a fluorophotometer every 15 min for 6 to 8 hr. the aqueous flow was calculated from the fluorophotometry data by the second method of jones and maurice. this flow was then compared to the known perfusion rate. the curve for total fluorescence decay was not pre ... | 1978 | 415021 |
| the thalamic afferents to the inferior parietal lobule of the rhesus monkey. | 1978 | 415071 | |
| the effects of severe keratitis on corneal transmission. | an investigation into the effects of keratitis on corneal light transmission is presented. transmission data from 9 diseased corneas are compared to those of 22 normal corneas in the 0.3-0.8 micron spectral range. rhesus monkey corneas were used in the study. several color photographs illustrate varieties of idiopathic keratitis in rhesus monkeys. | 1978 | 415084 |
| diurnal variation in plasma testosterone and cortisol in rhesus monkeys living in social groups. | concentrations of cortisol and testosterone in the plasma of adult male rhesus monkeys living in social groups were determined during a 27-h period. capture and venipuncture of experienced, conditioned animals did not lead to a fall in the concentration of testosterone in the plasma during the 90 min immediately after removal from the group. both plasm cortisol and plasma testosterone concentrations showed a significant fall and rise in samples collected every 3 h during a 27-h period, even thou ... | 1978 | 415103 |
| tubulin and microtubule-like structures in mammalian acrosomes. | immunofluorescence and electron microscopy were used to demonstrate the presence of tubulin and microtubule-like structures in rabbit and rhesus monkey sperm acrosomes. the distribution of tubulin within the acrosome appeared similar to the distribution of proteolytic activity, suggesting an association of proteinase with these structures. electron microscopy of rhesus monkey sperm incubated in vitro demonstrated a progressive condensation of the acrosomal matrix into microtubule-like structure. ... | 1978 | 415112 |
| role of vascular proliferation on angiographic appearance and encapsulation of experimental traumatic and metastatic brain abscesses. | experimental traumatic abscesses were produced in rhesus monkeys by intracerebral injection of nutrient agar contaminated with staphylococcus epidermidis, and metastatic abscesses were induced by intracarotid embolization of silicone cylinders contaminated with staphylococcus epidermidis. all monkeys underwent preoperative and serial postoperative carotid angiography. traumatic abscesses produced early capsular blushes and progressive anterior cerebral artery displacements. metastatic abscesses ... | 1978 | 415122 |
| serum amino acids during gestation of rhesus monkeys fed two different levels of protein. | 1978 | 415124 | |
| the visual pigments of rods and cones in the rhesus monkey, macaca mulatta. | 1. new microspectrophotometric measurements have been made of the photo-pigments of individual rods and cones from the retina of the rhesus monkey (macaca mulatta). the measuring beam was passed transversely through isolated outer segments. 2. the transverse absorbance for rods ranged from 0.02 to 0.04 and that for cones from 0.01 to 0.03. 3. the mean absorbance spectrum for rods (n = 25) had a peak of 502 +/- 2.7 nm. a digitonin extract from the same group of eyes gave a lambda-max. of 499 +/- ... | 1978 | 415133 |
| self-administration of heroin, acetylmethadol, morphine, and methadone in rhesus monkeys. | 1978 | 415198 | |
| ultradian rhythm of plasma noradrenaline in rhesus monkeys. | 1978 | 415252 | |
| gingival response to silk, cotton, and nylon suture materials. | silk, cotton, and nylon suture materials were implanted in the tunica propria of the gingiva in seven adult rhesus monkeys. the histologie study of twenty-four biopsy specimens indicated that there was neither an increase in the vascular permeability nor a leukocytic margination and migration into the tissues adjacent to the suture materials. however, there was a variable histiocytic reaction, with multinucleated cell formation. this reaction was quite intense with cotton, less intense with silk ... | 1978 | 415276 |
| cerebellar contribution to oculomotor function. | normal 38 juvenile rhesus monkeys were used to study cerebellar contribution to oculomotor function. (1) gaze nystagmus was seen only after bilateral flocculus lesions. (2) spontaneous nystagmus was observed after nodulus, flocculus and cerebellar nuclei lesions. (3) okn was severely impaired after bilateral flocculus and nodulus lesions. it was slightly impaired after dentate nucleus lesions in a long-term observation. (4) it is a very interesting finding that okn is severely impaired after des ... | 1977 | 415281 |
| anosmia in male rhesus monkeys does not alter copulatory activity with cycling females. | three adult male rhesus monkeys were tested daily with intact adult female partners over the course of four or five mentstrual cycles. the males were made permanently anosmic by chemical ablation of the olfactory epithelium after the second or fourth cycle was completed. all males continued to display typical cycles of copulation with their partners after the anosmia procedures, with the shortest latencies to ejaculation occurring during the periovulatory phase of the partner's ovulatory cycle. ... | 1978 | 415362 |
| toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rhesus monkeys (macaca mulatta) following a single oral dose. | 1978 | 415382 | |
| vasectomy in rhesus monkeys. iii. light microscopic studies of testicular morphology. | rhesus monkeys were randomly assigned to undergo various surgical procedures. the animals were followed from one to sixty-six weeks postvasectomy, at which time they were sacrificed and their tissues prepared for light and electron microscopy. vasectomy in the rhesus monkey, as in certain other species, appears to be a procedure not attended with widespread testicular atrophy or histologic evidence of impaired spermatogenic potential utilizing the procedures and postoperative periods studied. wh ... | 1978 | 415398 |
| plasmodium knowlesi malaria in the rhesus monkey. | twelve rhesus monkeys were inoculated intravenously with about 500 000 malaria parasites, plasmodium knowlesi. acute hemolysis occurred 5 days later, and all animals died on the 6th or 7th day after inoculation. all organs were gray-green to gray-brown because of deposition of hemoglobin and malaria pigments. this deposition was particularly striking in the lung, brain, abdominal fat and serous surfaces. microscopic changes indicative of acute hypoxia were found in the liver (centrilobular necro ... | 1978 | 415405 |
| a radioimmunoassay of oestrone in plasma. plasma levels of oestrone and oestradiol in oophorectomized rhesus monkeys during treatment with subcutaneous implants containing oestrone. | a highly specific antiserum to oestrone was used to develop a sensitive radioimmunoassay. plasma was generally analysed without prior separation of the oestrogens. a small amount of plasma (0.1-0.2 ml) was extracted once with diethyl ether. the above and previously described radioimmunoassays were used to estimate plasma levels of oestrogens in oophorectomized monkeys treated with subcutaneous oestrone implants. three monkeys received a rod containing 40 mg of oestrone. the rods were kept in pla ... | 1978 | 415474 |
| protein deprivation in primates. x. test performance of juveniles born of deprived mothers. | forty juvenile rhesus monkeys whose mothers were fed semisynthetic diets containing 13.4, 6.7, or 3.35% protein during pregnancy were tested as juveniles on four tests of perceptual-discrimination learning. all juveniles were well fed since birth. no significant differences in proficiency due to diet could be detected. it is concluded that thanks to the mother's proficient adaptation to the diet the fetus is well protected, and not deprived. | 1978 | 415589 |
| protein deprivation in primates. xi. determinants of weight change during and after pregnancy. | individual differences in weight gain of rhesus monkeys during pregnancy far exceed the variation in infant weight. weight gain thus reflects maternal adjustment to her physiological state in relation to her environment rather than growth of the infant. diets high in protein lead to great weight gain. skeletal length is positively correlated and conception weight negatively correlated with weight gain. season of pregnancy, length of gestation and sex of the infant are unrelated to weight gain. n ... | 1978 | 415590 |
| immunogenetic studies of rhesus monkeys. 8. a new reagent of the g blood group system and an example of the founder principle. | a new reagent called g-3' has been discovered which detects the product of the g3 allele, regardless of the other g allele in the genotype. with this new reagent we can delineate nine of 10 genotypes of the g blood group system. the explicit detection of g3 revealed an example of the founder principle in that the frequency of this allele between the feral and laboratory-reared monkeys was significantly different. | 1977 | 415641 |
| effect of staphylococcal enterotoxin b on cardiorenal functions in rhesus macaques. | selected cardiovascular and renal functions were measured for 5 hours in conscious, chair-restrained, female rhesus macaques (macaca mulatta) after iv (0.05 and 1.0 mg/kg) or oral (1.0 mg/kg) administration of staphylococcal enterotoxin b (seb). cardiovascular functions, renal hemodynamics, and renal metabolism were also studied between 6 and 11 hours after iv seb inoculation. oral seb produced few changes in cardiorenal functions. in contrast, iv seb produced hypotension, tachycardia, increased ... | 1978 | 415647 |
| [cellular composition of the lymph nodes of monkeys (rhesus macaque) under normal and experimental conditions]. | by means of mathematical methods, quantitative and qualitative changes were studied in different structural components of the mesenteric (ileocecal) lymph nodes in normal monkeys (macaca rhesus) and under per os administration of salmonella typhi murium, streptomycin-dependent. cellular composition was calculated in the cortical plateau, cortical (lymphoid) cords and in follicules. average percent of every cell type was determined. vaccine administration, was stated to inhibit cytopoiesis in the ... | 1978 | 415703 |
| experimental retinal vascular occlusion. i. pathogenesis of central retinal vein occlusion. | in 45 eyes of rhesus monkeys, five types of central retinal vascular occlusion were produced by lateral orbitotomy: group 1, central retinal vein occlusion (crvo) alone; group 2, crvo with simultaneous central retinal artery (cra) occlusion; group 3, crvo with transient clamping of the cra for either 2 to 2 1/2 hours (group 3a) or 6 to 7 1/2 hours (group 3b); and group 4, crvo with segmental retinal ischemia. the eyes were examined by fundus photography and fluorescein angiography for up to nine ... | 1978 | 415709 |
| ovulation induction by gonadotropin and prostaglandin treatments of rhesus monkeys and observations of the ova. | 1978 | 415767 | |
| functional development of the dorsolateral prefrontal cortex: an analysis utlizing reversible cryogenic depression. | the dorsolateral prefrontal cortex of rhesus monkeys was functionally inactivated by local hypothermia as the monkeys performed spatial delayed-response and spatial delayed-alternation tasks at different stages of postnatal development. cryogenic depression of prefrontal cortex at a temperature sufficient to induce 21--25% decrements in delayed-response performance in 34--36-month-old-monkeys, produced deficits of only 7--8% in 19--31-month-old and no detectable loss in younger monkeys, 9--16 mo ... | 1978 | 415802 |
| etiology of the negative chronotropic responses to transient coronary artery occlusion in the anesthetized rhesus monkey. | etiology of the negative chronotropic response to coronary artery occlusion was studied in chloralose-anesthetized monkeys. one-minute occlusion of the circumflex (circ) coronary artery resulted in marked negative chronotropic responses and consistent alterations in atrial electrograms. these responses were dependent on interruption of flow to a small proximal circ branch, and postmortem examination revealed that it perfused the sinus node region. the negative chronotropic response was not depen ... | 1978 | 415826 |
| adult male--infant interactions among monkeys living in nuclear families. | adult male rhesus monkeys were housed in nuclear families containing adult female mates, offspring, and other infants and adults. behaviors exhibited by the adult males were recorded 4 days per week over a 37-month period; in interactions involving other monkeys, the identity and the responses of those participants were also recorded. the results indicated that, although adult males were less active and more stable in their behavioral levels than mates or offspring, they clearly distributed both ... | 1977 | 415846 |
| comparative values of c3 in normal rhesus monkey and man. | 1977 | 415972 | |
| the qualitative evaluation of airway responses to immunologic and pharmacologic stimuli in rhesus monkeys. | this report describes the current status of a colony of rhesus monkeys composed of a group of animals with consistent asthmatic responses to ascaris antigen challenge, a variable group and a negative group. the cumulative experience with the consistent group of 5 animals totals 144 months of observation with 86 positive respiratory responses to 86 aerosol challenges. further studies compare rhesus airway responses to ascaris antigen, anti-ige, histamine, prostaglandin (pg)f2alpha, carbocholine, ... | 1978 | 416064 |
| pituitary-thyroid function in the rhesus monkey (macaca mulatta). | 1978 | 416160 | |
| regulation of thyrotrophin secretion by negative feedback of tri-iodothyronine on the hypothalamus. | bilateral injections of tri-iodothyronine (t3, 2 ng in 2 microliter artificial cerebrospinal fluid, csf) were made into the hypothalami of 15 hypothyroid rhesus monkeys (macaca mulatta) prepared with chronically implanted intrahypothalamic cannulae. in 29 out of 96 such injections, the concentration of thyrotrophin (tsh) in the plasma fell rapidly by more than 30% and returned to the basal value over the succeeding 48 h, in 13 experiments the fall was 20-30% and in the remaining 54 experiments t ... | 1978 | 416161 |
| experimental respiratory syncytial virus infection of four species of primates. | four species of nonhuman primates were inoculated intranasally with 10(3.1) to 10(3.7) plaque forming units (pfu) of respiratory syncytial (rs) virus. adults squirrel monkeys and newborn rhesus monkeys became infected and shed small quantities (peak titer 10(2.0) pfu/ml of nasopharyngeal swab specimen) of virus, but illness did not develop. infant cebus monkeys aged 2 months became infected, shed 10(2.3) to 10(3.8) pfu/ml of nasopharyngeal swab specimen, but did not become ill. chimpanzees aged ... | 1977 | 416176 |
| the reinforcing properties of procaine and d-amphetamine compared in rhesus monkeys. | twelve rhesus monkeys were studied under a fixed-ratio (fr) schedule of intravenous procaine or d-amphetamine injection from 8 a.m. to 4 p.m. daily. under the fr schedule, every nth lever press produced an injection. the fr value (n) and the dose per injection of procaine and d-amphetamine were varied systematically. at a fr value of 10, responding was maintained by doses of procaine ranging from 0.125 to 12 mg/kg/injection and by doses of d-amphetamine ranging from 0.01 to 0.1 mg/kg/injection. ... | 1978 | 416198 |
| development of a pulmonary technique to assess inhaled bronchoactive agents in the conscious rhesus monkey. | 1978 | 416200 | |
| effect of 1-(2,4-dichlorobenzyl)-indazole-3-carboxylic acid on sperm tails in rhesus monkeys. | large numbers of spermatozoa with bent or coiled tails were found in the ejaculates of rhesus monkeys treated with 1-(2,4-dichlorobenzyl-indazole-3-carboxylic acid (dica) (50 or 500 mg/kg for various periods). the defect appeared only in spermatozoa in the cauda epididymidis and consisted of axoneme disarrangement and loss of the fibre doublets. the coil was completely enclosed in a membrane. | 1978 | 416207 |
| effect of chronic oral methadone treatment on the growth of maturing monkeys. | three male rhesus monkeys drank methadone hydrochloride (1.0-2.5 mg/kg/day) in tang orange drink from age two to four years. their rate of body weight gain was faster than that found by other experimenters. in a second study one male monkey drank 2.0 mg/kg/day methadone while two others drank only tang from age 21/2 to 31/2 years. the rate of body weight gain was identical for the three monkeys, and was the same as that found in the previous study. the apparent augmentation of body weight gain i ... | 1977 | 416217 |
| pulmonary acariasis in an infant, colony-born rhesus monkey (macaca mulatta). | 1978 | 416293 | |
| acepromazine-ketamine anesthesia in the rhesus monkey (macaca mulatta). | six adult male rhesus monkeys (macaca mulatta) were anesthetized using a combination of acepromazine maleate and ketamine hydrochloride administered by intramuscular injection. this combination produced a smooth induction to anesthesia requiring less than 5 minutes. the average duration of anesthesia was slightly less than 1 hour and was safely prolonged with additional doses of ketamine. the depth of anesthesia was sufficient for minor surgical procedures and for precise radiological studies. n ... | 1978 | 416295 |
| the handedness of rhesus monkeys--i. distribution. | 1978 | 416370 | |
| hematologic and serum chemistry values following phencyclidine administration to macaca mulatta. | 1978 | 416520 | |
| comparative xenodiagnosis with three triatomine species of different hosts with natural and experimental chronic infections with trypanosoma (schizotrypanum) cruzi. | simultaneous xenodiagnosis was made of 29 patients with chronic chagas's disease, six naturally infected opossums (didelphis azarae) and of a rhesus monkey with an experimental chronic infection with trypanosoma (schizotrypanum) cruzi (peru strain). patients and opossums were from an endemic area in the state of bahia, brazil, where panstrongylus megistus is the sole domiciliary vector of the disease to man. various instars of p. megistus triatoma infestans and rhodnius prolixus were used. the p ... | 1978 | 416525 |
| attempts to induce immunological enhancement for kidney allografts in rhesus monkeys. | various rhesus alloantisera were tested for their capacity to induce enhancement of kidney allograft survival in d locus-incompatible rhesus monkeys. six experimental groups were investigated: 1, ten allografted monkeys remained untreated; 2, six recipients were treated with imuran and prednisolone; 3, eight rhesus monkeys were treated with a polyspecific "anti-sd" serum; 4, four animals were given oligospecific antikidney serum; 5, four monkeys were treated with oligospecific antiblood serum; a ... | 1978 | 416527 |
| the rhesus monkey as a preclinical model for bone marrow transplantation. | 1978 | 416528 | |
| transfer of 51cr platelets and 51chromium ions across the term rhesus monkey placenta. | 1978 | 416645 | |
| disruption of blood-retinal barrier at the retinal pigment epithelium after systemic urea injection. | electron microscopic studies were done on the structural alterations of retinal pigment epithelial cells occurring under osmotic stress utilizing rhesus monkeys and lanthanum nitrate as a tracer. fluorescein fundus angiography revealed leaking points of fluorescein from the choroid to the retina, and various degenerative alterations of the retinal pigment epithelial cells were observed in these leaking areas. some cells included many vacuoles in their cytoplasm, but diffusion of lanthanum from t ... | 1978 | 416648 |
| temporal relationships of estrogen, progesterone, and luteinizing hormone levels to ovulation in women and infrahuman primates. | these studies were undertaken to ascertain the interval between the estrogen and lh peaks and ovulation in women, rhesus monkeys, and baboons. estrogen, progesterone, and lh were measured by ria. ovulation was documented by visual examination of the ovaries, histology of the corpora lutea, and recovery of ova. the data for human subjects was based on a group of 23 normal women scheduled for surgical sterilization. blood was drawn daily between 8:30 and 10:30 p.m. beginning on day 10 of the cycle ... | 1978 | 416719 |
| cellular immunologic studies of malignant lymphoma in rhesus macaques. | cells from malignant lymphoma in 10 rhesus macaques were examined for lymphocyte surface markers. three had features of t cells, 5 had features of b cells, and 2 lacked evidence of either b- or t-cell differentiation. correlation between the histologic classification of cell type and the b- or t-cell nature of the neoplasms was not evident. evaluation of serum electrophoresis, mitogen responses tests, and previous histologic studies suggest that the development of the neoplastic lymphocyte proli ... | 1978 | 416735 |
| the reversible biotransformation of n-acetylprocainamide in the rhesus monkey. | the specific activity of 14c-n-acetylprocainamide (14c-napa) was measured in the 24-h urine of two rhesus monkeys given the labelled drug i.v. specific activity was found to decrease by 15.8% from the original value. this was attributed to an in vivo biotransformation of napa to procainamide (pca) and reacetylation of pca back to napa before it was eliminated in the urine. the major fraction of napa, 72.1% of the dose, was found to be excreted in the urine of monkeys in 48 h. | 1978 | 416831 |
| projections of lateral orbital cortex to sensory relay nuclei in the rhesus monkey. | 1978 | 416882 | |
| an autoradiographic, semistereotaxic mapping of major projections from locus coeruleus and adjacent nuclei in macaca mulatta. | the autoradiographic method was used to trace projections from the monkey locus coeruleus (lc) and adjacent nuclei (nn. parabrachiales, n. tractus mesencephalicus nervus trigemini, substantia grisea centralis). pathways attributed to lc are presented diagrammatically in a set of 26 coronal sections. they include a descending pathway along the tractus tegmentalis centralis, a caudal pathway entering the corpus medullaris cerebellaris via the lateral wall and roof of ventriculus quartus, and an as ... | 1978 | 416887 |
| intensity of stimulation and rod and cone response in clinical electroretinography. | we exposed adult rhesus monkeys who were fully dark adapted to paired flashes of white light which increased in intensity by increments of 0.1 log. units. as intensity increased, the amplitudes of both the cone and rod systems increased while the implicit times decreased so that the responses overlapped. high intensities produce a complex waveform which prevents separation of the rod and cone components or timing of the peaks. on the other hand, low intensities separate the early and late recept ... | 1978 | 416893 |
| radioimmunoassay of calcitonin in the plasma of rhesus monkey and man. | we describe a radioimmunoassay for rhesus monkey and human immunoreactive calcitonin, in which a selected goat anti-human calcitonin antiserum, 131i-labeled synthetic human calcitonin tracer, and purified synthetic human calcitonin standards were used. the mean basal concentration of calcitonin in normal monkey plasma (254 microgram/liter) was not significantly different from that in normal human plasma (217 microgram/liter). the data indicate that the method is sensitive (lower limit of detecti ... | 1978 | 416924 |
| endocrine regulation of fetal development and its relation to parturition in the rhesus monkey. | rhesus monkey fetuses were surgically prosencephalectomized (type 2) or functionally hypophysectomized (type 1) at 75 days gestation, then returned to the uterus until elective caesarean section on day 145--150 (term 167 days). deprivation of fetal hypothalamic releasing factors in type 2 and fetal pituitary tropic hormones in type 1 significantly delayed the ontogeny and functional development of fetal endocrine tissues. bone ossification and growth were significantly retarded in type 1 only, n ... | 1977 | 416938 |
| distribution of calcitonin cells in the thyroid glands of normal adult rhesus monkey macaca mulatta. | the calcitonin cells of adult rhesus monkey macaca mulatta are located in the central region of thyroid along the median axis. the anterior and posterior poles, the isthmus and peripheral regions of thyroid are completely devoid of c cells. the parathyroid also lacks c cells. | 1978 | 416967 |
| primate mesenteric blood flow. effects of vasopressin and its route of delivery. | the effects of vasopressin on blood flow in the superior mesenteric artery and on mean arterial pressure and portal venous pressure were measured in 7 rhesus monkeys. vasopressin was injected, as either a bolus, or infused both intravenously and intraarterially to assess the influence of the route of administration upon hemodynamic responses. dose-dependent decreases in superior mesenteric arterial flow were observed during both intraarterial and intravenous injections of vasopressin. no statist ... | 1978 | 416990 |
| effects of estradiol benzoate, estrone, and propionates of testosterone or dihydrotestosterone on sexual and related behaviors of ovariectomized rhesus monkeys. | 1977 | 417014 | |
| behaviorial effects of a synthetic mixture of aliphatic acids in rhesus monkeys (macaca mulatta). | 1977 | 417015 | |
| the rate of reflux fluid movement into the eye from schlemm's canal during hypotony in the rhesus monkey. | 1978 | 417043 | |
| perfusate effects upon resistance to aqueous humor outflow in the rhesus monkey eye. a comparison of glutathione-bicarbonate ringer's solution to pooled aqueous humor as perfusate. | in vivo perfusion of the anterior chamber of normal rhesus monkeys with pooled rhesus aqueous humor gives an initial total facility of 0.48 +/- 0.08 (+/-s.e.) microliter/min/mm hg. with continued intermittent perfusion for 2 hr this value increased only slightly to 0.57 +/- 0.10 microliter/min/mm hg. perfusion of the paired eyes of the same monkeys with glutathionebicarbonate ringer's solution gives an initial total facility of 0.55 +/- 0.08 microliter/min/mm hg. this value increased to 1.21 +/- ... | 1978 | 417044 |
| static lung mechanics of intact and excised rhesus monkey lungs and lobes. | subdivisions of lung volume and pressure-volume (pv) curves of the lung and chest wall (cw) were measured in 12 rhesus monkeys (macacca mulatta) under pentobarbital anesthesia. in addition, volumes and pv curves were obtained on the excised lungs and lobes of 12 cynomolgus monkeys (m. fasicularis). boyle's law was used to determine functional residual capacity (frc) in the intact animals and water displacement to determine minimal volume (mv) in the excised lungs. total lung capacity (tlc = lung ... | 1978 | 417053 |
| viremia and serum antibodies in macacus rhesus monkey after inapparent infection with european tick-borne encephalitis virus. | 1. inapparent infection was called forth in m. rhesus monkeys by means of subcutaneous inoculation of etbe virus. 2. viremia was found in 18 (86 per cent) of 21 monkeys. in all the 18 monkeys, specific virus-neutralizing antibodies were found; in 17 of them complement-fixing antibodies developed in addition. 3. neutralizing antibodies (n greater than or equal to 1.7 log10) were first recorded on 10th day with a peak on 32nd day, retaining, after a small decrease, a relatively high level in all r ... | 1977 | 417136 |
| effect of peroral administration of xylitol on exocrine secretions of monkeys. | the effects of the administration of xylitol on the biochemical properties of monkey parotid and submandibular saliva and lacrimal fluid were investigated. monkeys (macaca mulatta) were fed either a sucrose or xylitol diet for 3 days. ingestion of xylitol was associated with a significant increase of the activity of the salivary lactoperoxidase. the concentration of protein was also increased. higher lactoperoxidase activity was found in parotid than in submandibular saliva. the concentrations o ... | 1978 | 417156 |
| pharmacokinetic profile of clonazepam in rhesus monkeys. | 1978 | 417166 |