Publications

oxidative stress in pelophylax esculentus complex frogs in the wild during transition from aquatic to terrestrial life.	during life, anuran individuals undergo drastic changes in the course of transition from aquatic to terrestrial habitat, when they are faced with metabolically demanding processes (growth, responses to developmental pressures), which result in increased production of reactive oxygen species (ros), signaling molecules involved in development that can induce oxidative damage and stress. this situation can be further complicated by environmental influences. the aim of this study was to investigate ...	2019	31082485
population genomics of an exceptional hybridogenetic system of pelophylax water frogs.	hybridogenesis can represent the first stage towards hybrid speciation where the hybrid taxon eventually weans off its parental species. in hybridogenetic water frogs, the hybrid pelophylax kl. esculentus (genomes rl) usually eliminates one genome from its germline and relies on its parental species p. lessonae (genomes ll) or p. ridibundus (genomes rr) to perpetuate in so-called l-e and r-e systems. but not exclusively: some all-hybrid populations (e-e system) bypass the need for their parental ...	2019	31382876
variation in hybridogenetic hybrid emergence between populations of water frogs from the pelophylax esculentus complex.	many closely related species are capable of mating to produce hybrid offspring, which are usually sterile. nevertheless, altering the gametogenesis of hybrid offspring can rescue hybrids from sterility by enabling asexual reproduction. hybridogenesis is one of the most complicated asexual reproductive modes, and it includes drastic genome reorganization only in the germline; this is achieved through elimination of one parental genome and duplication of the remaining one to restore diploid chromo ...	2019	31675368
distribution of gonadotropin-inhibitory hormone (gnih)-like immunoreactivity in the brain and pituitary of the frog (pelophylax esculentus) during development.	gonadotropin-inhibitory hormone (gnih) is a newly discovered hypothalamic rfamide peptide that influences reproduction by regulating brain and pituitary neuroendocrine functions in vertebrates. we report here for the first time, the ontogenetic description of gnih-like immunoreactivity in the brain, olfactory system, and pituitary of the frog, pelophylax esculentus. gnih-like immunoreactive (gnih-ir) elements were first observed in larvae at stage 24 in the olfactory mucosa, ventral telencephalo ...	2020	31848753
biochemical parameters in skin and muscle of pelophylax kl. esculentus frogs: influence of a cyanobacterial bloom in situ.	there is little information in scientific literature as to how conditions created by a microcystin (mc) producing cyanobacterial bloom affect the oxidant/antioxidant, biotransformation and neurotoxicity parameters in adult frogs in situ. we investigated biochemical parameters in the skin and muscle of pelophylax kl. esculentus from lake ludaš (serbia) by comparing frogs that live on the northern bloom side (bs) of the lake with those that inhabit the southern no-bloom side (nbs). a higher protei ...	2020	31896464
helminth species and infracommunities in frogs pelophylax ridibundus and p. esculentus (amphibia: ranidae) in northern ukraine.	the study aims to characterise and compare the helminth assemblages and helminth infracommunities in the marsh frog, pelophylax ridibundus and the edible frog, p. esculentus collected in the northern part of ukraine.	2020	31974765
zinc modulation of proton currents in a new voltage-gated proton channel suggests a mechanism of inhibition.	the hv 1 voltage-gated proton (hv 1) channel is a key component of the cellular proton extrusion machinery and is pivotal for charge compensation during the respiratory burst of phagocytes. the best-described physiological inhibitor of hv 1 is zn2+ . externally applied zncl2 drastically reduces proton currents reportedly recorded in homo sapiens, rattus norvegicus, mus musculus, oryctolagus cuniculus, rana esculenta, helix aspersa, ciona intestinalis, coccolithus pelagicus, emiliania huxleyi, da ...	2020	32160407
the combined effects of temperature and aromatase inhibitor on metamorphosis, growth, locomotion, and sex ratio of tiger frog (hoplobatrachus rugulosus) tadpoles.	the tiger frog (hoplobatrachus rugulosus) is widely raised by many farms in southern region of china as an economically edible frog. the growth, development, and sexual differentiation of amphibians are influenced by temperature and steroid hormone level. however, the problem of hormone residues is caused by the addition of exogenous hormones in frog breeding, it is worth considering whether non-sterol aromatase inhibitors can be used instead of hormones.	2020	32219039
micronuclei in germ cells of hybrid frogs from pelophylax esculentus complex contain gradually eliminated chromosomes.	in most organisms, cells typically maintain genome integrity, as radical genome reorganization leads to dramatic consequences. however, certain organisms, ranging from unicellular ciliates to vertebrates, are able to selectively eliminate specific parts of their genome during certain stages of development. moreover, partial or complete elimination of one of the parental genomes occurs in interspecies hybrids reproducing asexually. although several examples of this phenomenon are known, the molec ...	2020	32457346
vegetation cover induces developmental plasticity of lateralization in tadpoles.	lateralization of cognitive functions influences a large number of fitness-related behaviors and shows, in most species, substantial variation in strength and direction. laboratory works and field data have suggested that this variation is often due to adaptive phenotypic plasticity. strong lateralization should be favored in some ecological conditions, for example, under high risk of predation. for anuran tadpoles, the presence of cover affects predation risk, with tadpoles being more exposed t ...	2020	32617087
ranacyclin-nf, a novel bowman-birk type protease inhibitor from the skin secretion of the east asian frog, pelophylax nigromaculatus.	serine protease inhibitors are found in plants, animals and microorganisms, where they play important roles in many physiological and pathological processes. inhibitor scaffolds based on natural proteins and peptides have gradually become the focus of current research as they tend to bind to their targets with greater specificity than small molecules. in this report, a novel bowman-birk type inhibitor, named ranacyclin-nf (rnf), is described and was identified in the skin secretion of the east a ...	2020	32630758
celebrating 50+ years of research on the reproductive biology and endocrinology of the green frog: an overview.	this issue is dedicated to the late professor giovanni chieffi, and this article is an overview of the research on comparative endocrinology of reproduction using rana esculenta (alias pelophylax esculentus) as a model system. starting from the early 1970s till today, a large quantity of work have been conducted both in the fields of experimental endocrinology and in the definition of the diffuse neuroendocrine system, with a major focus on the increasing role of regulatory peptides. the various ...	2020	32739437
hepatic oxidative stress and neurotoxicity in pelophylax kl. esculentus frogs: influence of long-term exposure to a cyanobacterial bloom.	although the long-term exposure of aquatic organisms to cyanobacterial blooms is a regular occurrence in the environment, the prooxidant and neurotoxic effects of such conditions are still insufficiently investigated in situ. we examined the temporal dynamics of the biochemical parameters in the liver of pelophylax kl. esculentus frogs that inhabit the northern (n) side of lake ludaš (serbia) with microcystins (mcs) produced in a cyanobacterial bloom over three summer months. the obtained data w ...	2021	32853936
larval gnathostomes and spargana in chinese edible frogs, hoplobatrachus rugulosus, from myanmar: potential risk of human infection.	chinese edible frogs, hoplobatrachus rugulosus, were examined to estimate the potential risks of human gnathostomiasis and sparganosis in myanmar. a total of 20 frogs were purchased in a local market of yangon and examined with naked eyes and the artificial digestion method after skin peeling in june 2018 and june 2019. larvae of gnathostomes and spirometra (=spargana) were detected in 15 (75.0%) and 15 (75.0%) frogs with average intensities of 10.5 and 6.3 larvae per infected frog, respectively ...	2020	32871642
kisspeptins, new local modulators of male reproduction: a comparative overview.	spermatogenesis is a complex process that leads to the production of male gametes within the testis through the coordination of mitotic, meiotic and differentiation events, under a deep control of endocrine, paracrine and autocrine modulators along the hypothalamus-pituitary-gonad (hpg) axis. the kisspeptin system plays a fundamental role along the hpg axis as it is the main positive modulator upstream of the hypothalamic neurons that secrete the gonadotropin releasing hormone (gnrh), the decape ...	2020	32950583
author correction: micronuclei in germ cells of hybrid frogs from pelophylax esculentus complex contain gradually eliminated chromosomes.	an amendment to this paper has been published and can be accessed via a link at the top of the paper.	2020	33177602