Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| structure and genomic organization of proretrovirus-like elements partially eliminated from the somatic genome of ascaris lumbricoides. | a clone containing a middle repetitive element next to satellite dna has been isolated from a germ line genomic library of the chromatin eliminating nematode ascaris lumbricoides var. suum. the structure of this element has been elucidated by comparison of several clones containing the element in different environments. it is flanked by 256-bp-long terminal repeats (ltrs) and has an internal region of approximately 7 kb. the nucleotide sequences of both the 5' and the 3' ltrs have been determine ... | 1986 | 3816762 |
| chronic allergic airway disease in the sheep model: functional and lung-lavage features. | we developed an animal model of chronic allergic airway disease by repeatedly exposing nine sheep to tracheal instillation of ascaris antigen until stable increase in lung resistance at three times control in six reactive sheep (group c) was obtained. they were then compared to the three nonreactive sheep (group b) and a control group of eight sheep exposed to saline only (group a) in terms of pulmonary function tests and bronchoalveolar lavage (bal) analyses. lung resistance was 1.5 +/- 0.3 cm ... | 1987 | 3819218 |
| adenylate cyclase activity is absent in inactive and motile sperm in the nematode parasite, ascaris suum. | 1986 | 3819975 | |
| collection of fertile ascaris suum eggs. | 1986 | 3819976 | |
| isolation of nematode major sperm proteins. | 1986 | 3821572 | |
| [incidence of ascariasis and lambliasis in children with allergic diseases of the respiratory system]. | 1986 | 3822911 | |
| effect of ascaris lumbricoides on zinc level in blood and urine. | 1986 | 3824556 | |
| recurrent pancreatitis caused by a calcified ascaris in the duct of wirsung. | a case report of recurrent pancreatitis in a 20-yr-old woman due to an impacted calcified ascaris remnant within the duct of wirsung is presented. endoscopic retrograde cholangiography identified a filling defect in the proximal main pancreatic duct. transampullary endoscopic retrieval failed to extract the calculus and operative intervention was required to remove the calcified worm remnant. | 1987 | 3826032 |
| [the incidence of intestinal helminths in samsun district]. | 17954 stool specimens that were brought to the microbiology department of ondokuzmayis university were investigated in regard to the intestinal helminth eggs and the incidence was found to be 16% and 62% of them being ascaris lumbricoides. the incidence of the intestinal helminth which was %21.08 in 1978 was found to be decreased to %10.45 in 1984. | 1985 | 3831725 |
| [viability of ascaris lumbricoides ova after human treatment with specific drugs. i--levamisole and pyrantel pamoate]. | 1985 | 3832340 | |
| population dynamics and chemotherapeutic control of trichuris trichiura infection of children in jamaica and st. lucia. | population dynamical parameters of trichuris trichiura infections in children were estimated from longitudinal intensity and prevalence data from a population (n = 23) in a children's home in jamaica. the theoretical predictions of a deterministic model incorporating these parameters were approximated to observed horizontal-age prevalence data from a naturally infected population (n = 203) of children in a st. lucian village, and a rough estimate of the basic reproductive rate (ro = 8-10) of t. ... | 1985 | 3832488 |
| canine and human gastrointestinal helminthiasis of the kainji lake area, nigeria. | an investigation into gastrointestinal helminthiasis in human and dog population of the kainji lake area revealed a high prevalence of helminthiasis which may be due to lack of adequate health and veterinary facilities; crowdiness and squalid environment. the prevalent parasites in humans were ancylostoma sp, 40.33%; ascaris lumbricoides, 44.07% and strongyloides stercoralis 4.05%, while in dogs ancylostoma sp, 36.95%, dipylidium caninum, 28.26%, echinococcus granulosus, 8.69% and s. stercoralis ... | 1985 | 3833832 |
| effect of amoscanate derivative cgp 8065 on aminoacyl-trna synthetases in ascaris suum. | evidence is provided for the occurrence of a multienzyme complex consisting of several aminoacyl-trna synthetases besides 'free enzymes' in ascaris suum. the molecular mass of this complex was calculated to be about 10(6) daltons, compared to about 150 000 daltons for the seryl-trna synthetase. leucyl-, isoleucyl-, arginyl- and lysyl-trna synthestases were found in the high molecular weight fraction. the michaelis constants of these aminoacyl-trna synthetases were found to be in the range of 4 t ... | 1985 | 3838573 |
| calcium-dependent muscle contraction in obliquely striated ascaris suum muscle. | the regulatory proteins of ascaris suum striated skeletal muscle were partially purified and characterized. a tropomyosin isoform (mr 41k) and three troponin subunits identified as troponin t (mr 37.5k), troponin i (mr 25.5k) and troponin c (mr 18.5k) were purified. three myosin light chains (mr 25k, 19k, and 17k) were isolated from washed ascaris actomyosin; the 19k subunit was phosphorylated in vitro. a calcium/calmodulin-dependent myosin light chain kinase activity was identified in the muscl ... | 1985 | 3840425 |
| parasite-specific interaction of n-[4-(4'nitroanilino)-phenyl]-s-(beta-carboxyethyl)-dithiocar bamic acid-ester with arginyl-trna-synthetase from dirofilaria immitis. | a potent inhibition of arginyl-trna-synthetase from dirofilaria immitis by n-[4-(4'nitroanilino)-phenyl]-s-(beta-carboxylethyl)-dith iocarbamic acid-ester (cgp 8065) is demonstrated, which indicates the charging of amino acids to trna as a possible target for the chemotherapeutic attack by this filaricidal compound. cgp 8065 competes with atp; the inhibition constant was determined to be 13 micrograms ml-1 (34 microm). the michaelis constants for arginine and atp were found to be 5 microm and 0. ... | 1985 | 3841408 |
| ascaris suum: biosynthesis and isoinhibitor profile of chymotrypsin/elastase isoinhibitors. | chymotrypsin/elastase isoinhibitors were radiolabeled when live, adult ascaris suum were incubated in tissue culture medium (nctc-135) supplemented with l-[35s]cysteine. this is the first demonstration that the synthesis of these proteins occurs in a. suum; the isoinhibitors are not host products utilized by the parasite against its host. of five chymotrypsin/elastase isoinhibitors demonstrable in a. suum, only isoinhibitors 1, 4, and 5 were found in each worm. the amino acid sequences of these ... | 1985 | 3846534 |
| a study of the effectiveness of mebendazole and pyrantel pamoate as a combination anthelmintic in papua new guinean children. | a mixture of 150 mg mebendazole and 30mg pyrantel pamoate was given on 3 consecutive or near-consecutive days to 70 children infected with one or more of necator americanus, ascaris lumbricoides, strongyloides stercoralis, s. fuelleborni-like and trichuris trichiura. this treatment had an efficacy of 95 per cent for n. americanus infections, 100 per cent for a. lumbricoides, 57 per cent for strongyloides spp., and 75 per cent for t. trichiura. the results indicate that the treatment given is eff ... | 1985 | 3862315 |
| changes in the white blood picture during experimental larval ascariasis, toxocariasis and toxascariasis. | haematological changes were studied in rabbits experimentally infected with different doses of ascaris suum, toxacara canis and toxascaris leonina. the numbers of leucocytes, eosinophiles and neutrophiles were changed and the strongest eosinophila was observed between the 2nd and 3rd week of infection (5.2-7.1%). the intensity of reaction was not related to the used infection dose. the eosinophilia was always lower in toxocariasis and toxascariasis than in ascariasis at identical doses of infect ... | 1985 | 3862632 |
| effect of repeated antigen exposure on antigen-and mediator-induced bronchospasm in sheep. | we studied the effects of repeated exposures of antigen on airway reactivity to mediators of anaphylaxis and immediate response to the antigen. seven antigen-sensitive sheep were exposed to aerosols of ascaris suum antigen 5 times biweekly; a control group of seven sheep underwent the same exposure regimen with saline vehicle. sheep were assigned to experimental (ascaris) or control groups so the distribution of animals with regard to bronchial reactivity to mediators was about the same. airway ... | 1985 | 3865925 |
| the regulation of tissue eosinophilia. iii. in vitro production of eosinophil-directed chemotactic inhibitory factor by t lymphocytes of complete freund's adjuvant-treated guinea-pigs. | guinea-pig spleen cells treated with complete freund's adjuvant (cfa) produce eosinophil-directed chemotactic inhibitory factors (ecif). the inhibition is selective for the response of eosinophils to delayed ecf-a, which had been isolated from 24-hr-old inflamed skin lesions induced by dnp-ascaris extract in sensitized animals and had been confirmed as being a t lymphocyte-derived lymphokine. ecif activity is absorbed by incubation with eosinophils, but not with macrophages or neutrophils. the c ... | 1985 | 3873403 |
| antigen sensitization and methacholine responses in dogs with hyperreactive airways. | antigen sensitization was induced in six basenji-greyhound (bg) dogs by weekly aerosol exposure to ascaris suum. the effects on airway responsiveness to inhaled methacholine were studied before and at least 2 wk following ascaris sensitization. all dogs developed detectable serum levels of ascaris-specific immunoglobulin e (ige), and five out of six dogs developed airway responsiveness to antigen over the 4- to 6-mo period. this was accompanied by a decrease rather than an increase in airway res ... | 1985 | 3884573 |
| immunochemical comparison of lipoamide dehydrogenases from various sources and reactivity of various lipoamide dehydrogenases with rat heart pyruvate dehydrogenase-subcomplex. | lipoamide dehydrogenases from various sources were purified and their immunochemical properties were compared. antibody against rat lipoamide dehydrogenase reacted with rat, human, pig, pigeon and frog enzymes, but not with enzymes from e. coli, yeast and ascaris. anti-ascaris enzyme and anti-e. coli enzyme antibodies reacted with ascaris and e. coli enzymes, respectively. the pyruvate dehydrogenase subcomplex, which consists of pyruvate dehydrogenase and lipoate acetyltransferase, was prepared ... | 1985 | 3893428 |
| intermediate filaments in non-neuronal cells of invertebrates: isolation and biochemical characterization of intermediate filaments from the esophageal epithelium of the mollusc helix pomatia. | to screen invertebrate tissues for the possible expression of intermediate filaments (ifs), immunofluorescence microscopy with the monoclonal antibody anti-ifa known to detect all mammalian if proteins was used (pruss, r. m., r. mirsky, m. c. raff, r. thorpe, a. j. dowding, and b. h. anderton. 1981. cell, 27:419-428). in a limited survey, the lower chordate branchiostoma as well as the invertebrates arenicola, lumbricus, ascaris, and helix pomatia revealed a positive reaction primarily on epithe ... | 1985 | 3894375 |
| increased multiplication of dengue virus in mouse peritoneal macrophage cultures by treatment with extracts of ascaris-parascaris parasites. | methylcellulose-elicited peritoneal macrophages from balb/c mice were cultivated in vitro and inoculated with dengue virus (dv). at intervals thereafter portions of the culture fluids were taken and titrated for viral infectivity. extracts from ascaris suum and parascaris equorum, either crude or sephadex g-100 fractionated, were examined for effects on the multiplication of dv. the macrophage cultures treated with the above substances produced larger amounts of dv compared with untreated contro ... | 1985 | 3894890 |
| studies on the traditional herbal anthelmintic chenopodium ambrosioides l.: ethnopharmacological evaluation and clinical field trials. | infusions and decoctions of the leaves, roots and inflorescences of the herbaceous shrub chenopodium ambrosioides (american wormseed, goosefoot, epazote, paico) and related species indigenous to the new world have been used for centuries as dietary condiments and as traditional anthelmintics by native peoples for the treatment of intestinal worms. commercial preparations of oil of chenopodium and its active constituent, ascaridol, obtained by steam distillation, have been and continue to be, use ... | 1985 | 3906906 |
| [met-enkephalin-arg-gly-leu-like immunoreactivity-containing nerve elements in the guinea-pig intestine. an immunohistochemical study using whole mount preparations]. | the localization and distribution of met-enkephalin-arg-gly-leu (met-enk-arg-gly-leu)-like immunoreactivity in whole mount preparations of different layers of guinea-pig gut (duodenum, jejunum, ileum and proximal colon) were studied by sternberger's indirect immunocytochemistry. anti-met-enk-arg-gly-leu serum used as the primary antiserum was raised in a rabbit against synthetic met-enk-arg-gly-leu coupled to ascaris protein by the glutaraldehyde method. the results obtained were summarized as f ... | 1985 | 3908153 |
| increased in vitro airway responsiveness in sheep following repeated exposure to antigen in vivo. | we have studied the effect of repeated in vivo antigen exposure on in vitro airway responsiveness in sensitized sheep. fourteen sheep underwent five biweekly exposures to aerosolized ascaris suum antigen or saline. following this exposure regimen, the animals were killed and tracheal smooth muscle and lung parenchymal strips were prepared for in vitro studies of isometric contraction in response to histamine, methacholine, prostaglandin f2 alpha, and a thromboxane a2 analogue. no alteration in t ... | 1985 | 3908441 |
| influence of chronic antigen exposure on the metabolism of pgh2 by microsomal preparations of airway and parenchymal tissues in the sheep. | the effects of repeated antigen exposure on the synthesis of mediators by lung tissues are not well understood. to investigate the influence of antigen challenge on the synthesis of prostaglandins by central airway and peripheral lung tissues, fourteen sensitive sheep underwent biweekly exposure to aerosolized ascaris suum antigen (7) or saline (7). following the fifth exposure, microsomal and high speed supernatant fractions were prepared from trachealis muscle and lung parenchyma. synthesis of ... | 1985 | 3911292 |
| nutritional aspects of parasitic infection. | the nutritional basis of the ecological relationship between parasites and their hosts is reviewed using examples of the parasitic infections of man whenever possible. two important points are discussed first: the distinction between parasitic infection and parasitic disease, and the concepts of synergism or antagonism between undernutrition and parasitic disease. the effects of parasites on the nutritional status of the host are examined in four ways. first, in terms of the ways in which parasi ... | 1985 | 3914654 |
| the interaction of aspartic proteinases with naturally-occurring inhibitors from actinomycetes and ascaris lumbricoides. | 1985 | 3916913 | |
| arachidonic acid release in rat peritoneal mast cells stimulated with antigen, ionophore a23187, and compound 48/80. | rat peritoneal mast cells respond to various types of secretagogues, such as antigen (receptor-mediated), a23187 (calcium mobilizing), and compound 48/80 (membrane perturbing), and release arachidonic acid from membrane phospholipids prelabeled with [3h]arachidonate. the rate of arachidonic acid liberation varied from one stimulant to the other. ionophore a23187 (0.1 micrograms/ml) appeared to be most potent in releasing arachidonate among the three stimulants at which doses each secretagogue ca ... | 1985 | 3921018 |
| activity of rapidly-adapting receptors to histamine and antigen challenge before and after sodium cromoglycate. | sodium cromoglycate (scg) blocks histamine release from sensitized mast cells challenged by antigen in vitro. yet, not all the observed effects of scg in vivo can be explained by this mechanism alone. rapidly-adapting or "irritant" receptors (rar) are thought to mediate reflex bronchoconstriction. others have proposed that scg may desensitize these receptors to histamine. we administered aerosols of histamine (100 micrograms/ml given for 3 min) before and after scg (20 mg/ml aerosol for 5 min) t ... | 1985 | 3923960 |
| production of early and late pulmonary responses with inhaled leukotriene d4 in allergic sheep. | some allergic sheep respond to inhalation of ascaris suum antigen with both immediate and late increases in airflow resistance (late response). the mechanism of the late response is unknown but recent evidence suggests that the initial generation of slow-reacting substance of anaphylaxis (srs-a) immediately after antigen challenge is a necessary pre-requisite for the physiologic expression of this late response. based on this evidence we hypothesized that airway challenge with leukotriene d4 (lt ... | 1985 | 3925500 |
| ascaris suum: localization by immunochemical and fluorescent probes of host proteases and parasite proteinase inhibitors in cross-sections. | cross-sections of muscle, intestine, and genital tract fluoresced in defined locations when live ascaris suum adults were incubated in medium containing chymotrypsin liganded with fluorescein-5-isothiocyanate. this suggests that the protease, or portions of it, are assimilated by a. suum. a. suum chymotrypsin/elastase isoinhibitors were found in muscle sarcolemma, eggs, sperm, and intestine, and host chymotrypsin was localized in the same regions of these tissues by immunofluorescence and immuno ... | 1985 | 3928399 |
| [digestibility of nutrients in a feed mixture in certain swine helminthiases]. | the average digestibility coefficients of feed mixture nutrients in pigs infected medium severely to severely by the helminths ascaris suum and oesophagostomum dentatum were lower in comparison with the post-dehelminthization condition (dry matter by 3.1%, crude protein by 6.7%, fat by 8.9%, nitrogen-free extracts and fibre by 2.2%, organic matter by 3.1%). the content of total digestible nutrients made 679 g in infected pigs and 708 g in dehelminthized pigs. in the period following the experime ... | 1985 | 3931335 |
| the prevalence and intensity of s. mansoni and ascaris lumbricoides in a fishing village of kigungu--entebbe. | 1985 | 3932061 | |
| comparative purification and characterization of invertebrate muscle glycogen synthase from the porcine parasite ascaris suum. | glycogen synthase has been purified from the obliquely striated muscle of the swine parasite ascaris suum. the muscle contains a concentration of glycogen synthase and glycogen which is 20-fold and 15-fold, respectively, greater than rabbit skeletal muscle. the enzyme could not be solubilized with salivary amylase, but partial solubilization was achieved by activation of endogenous phosphorylase. the enzyme was purified to 85-90% homogeneity (specific activity = 4.3 units/mg) by deae-cellulose, ... | 1985 | 3934170 |
| ascaris suum: regulation of myosin light chain phosphorylation from adult skeletal muscle. | the regulatory myosin light chain in ascaris suum muscle was isolated in a phospho and dephosphoform. in freshly dissected tissue or in control muscle segments perfused with saline, approximately 48% of the total myosin light chain pool was phosphorylated. perfusion with acetylcholine caused a dose dependent increase in muscle contraction but no change in myosin light chain phosphorylation. in contrast, perfusion with gamma-aminobutyric acid resulted in a dose dependent relaxation of a. suum mus ... | 1986 | 3943587 |
| hybridization between fructose diphosphate aldolase subunits derived from diverse biological systems: anomolous hybridization behavior of some aldolase subunit types. | in the present studies we investigated the abilities of fructose diphosphate aldolase subunits derived from diverse biological sources to form stable heterotetramers with each other in vitro. aldolase c subunits isolated from chicken brain readily "hybridized" with aldolase subunits derived from lobster muscle and wheat germ following reversible acid dissociation of mixtures of these enzymes; however, appreciable amounts of stable heterotetramers containing chicken c subunits and aldolase subuni ... | 1986 | 3947066 |
| fatal human ascariasis following secondary massive infection. | more than 796 ascaris lumbricoides worms weighing 550 g were recovered at autopsy from a 2-year-old black south african girl. most of the worms were taken from necrotic small intestine, but worms were also in the stomach, esophagus, intrahepatic and extrahepatic bile ducts, and gallbladder. the worms had caused torsion and gangrene of the ileum, which was interpreted as the cause of death. worms were formalin-fixed and individually weighed. there were 796 intact worms and 112 appreciably large ( ... | 1986 | 3953945 |
| intestinal basement membrane of ascaris suum. molecular organization and properties of the collagen molecules. | the collagenous components of ascaris suum intestinal basement membrane were isolated by extraction with 0.1 m tris-hc1, 0.5 m nac1, 0.5% 2-mercaptoethanol, ph 8.3, and sephacryl s-300 gel filtration. rotary-shadowing electron microscopy showed that the collagenous components occur as monomers and dimers with mean contour lengths of 469 +/- 21 and 918 +/- 24 nm, respectively. the molecules each contain a globular domain, with that of the dimer being slightly larger than that of the monomer. elec ... | 1986 | 3957913 |
| aerosolized leukotriene d4 converts monkeys that are negative aerosolized ascaris responders to positive airway responders. | we designed studies to determine if leukotriene d4 (ltd4) could alter airway reactivity such that rhesus monkeys with positive skin reactivity and consistently negative airway responses would respond to ascaris airway challenge. the experiments were complicated by the observation that aerosolized ltd4 would occasionally increase airway hyperreactivity in some monkeys used as controls such that an airway response occurred to saline, the diluent for ascaris antigen. in spite of this, we were able ... | 1986 | 3959748 |
| an investigation of the prevalence of intestinal parasites in pre-school children in ghana. | evidence for the presence of 11 intestinal parasites in pre-school children from 4 rural villages in ghana was obtained from an examination of stool samples. striking differences were detected between the prevalence of some of the 6 common infections in the 4 villages. the prevalence of ascaris lumbricoides varied from about 76% in one village (oshiyie, coastal savanna) to apparently 0% in another (akuma, forest zone). no differences in prevalence for any infection were observed to be sex depend ... | 1986 | 3960592 |
| screen for anthelmintics, using larvae of ascaris suum. | a multiwell culture system was used to assay the effects of 12 known anthelmintic compounds on ascaris suum larval development from 2nd-stage (l2; hatched from eggs) to early 3rd-stage (l3) and from in vivo-derived late l3 to early 4th-stage (l4). larval survival, development, and motility were monitored for drug effects. development of l2 to l3 was sensitive to thiabendazole, albendazole (abz), abz/sulfoxide, abz/sulfone (so), mebendazole, l-tetramisole, d-tetramisole, piperazine, or closantel ... | 1986 | 3963590 |
| identification of excitatory and inhibitory motoneurons in the nematode ascaris by electrophysiological techniques. | a physiological preparation in which it is possible to record responses in muscle to stimulation of single motoneurons of the nematode ascaris lumbricoides is described. with this preparation we have determined the physiological sign (e or i; excitatory or inhibitory) of the neuromuscular synapses of 21 identified motoneurons--12 are excitatory and 9 inhibitory. ascaris motoneurons had previously been classified by morphological criteria into seven classes (stretton, a. o. w., r. m. fishpool, e. ... | 1985 | 3965635 |
| excitatory and inhibitory activity in the dorsal musculature of the nematode ascaris evoked by single dorsal excitatory motonerons. | a physiological preparation, in which identified motoneurons of the nematode ascaris lumbricoides can be individually stimulated, was used to map the response evoked by single dorsal excitatory (de) motoneurons in muscle cells innervated along the length of the dorsal nerve cord. as previously reported (walrond, j. p., i. s. kaas, a. o. w. stretton, and j. e. donmoyer (1985) j. neurosci. 5: 1-8), stimulation of a de cell produces excitatory responses in muscle cells which it directly innervates. ... | 1985 | 3965640 |
| reciprocal inhibition in the motor nervous system of the nematode ascaris: direct control of ventral inhibitory motoneurons by dorsal excitatory motoneurons. | in previous physiological experiments (stretton, a. o. w., r. m. fishpool, e. southgate, j. e. donmoyer, j. p. walrond, j. e. r. moses, and i. s. kass (1978) proc. natl. acad. sci. u. s. a. 75: 3493-3497), we have shown that the dorsal cord of the nematode ascaris lumbricoides includes the processes of three types of dorsal excitatory (de) motoneurons and one type of ventral inhibitory (vi) motoneuron. ultrastructural studies have revealed that the axons of the de motoneurons make monosynaptic c ... | 1985 | 3965648 |
| influence of an experimental infection of ascaris suum on performance of pigs. | thirty-two pigs (average 26.6 kg live weight) were individually housed and fed to study the effect of an infection of ascaris suum (either 0, 600, 6,000 or 60,000 a. suum eggs/pig) on performance of growing-finishing pigs. increasing the level of a. suum infection produced linear (p less than .07) and quadratic (p less than .09) effects on final weight, weight gain and average daily gain. feed to gain ratio and number of a. suum worms recovered from the intestines of pigs at slaughter increased ... | 1985 | 3972742 |
| steroidal enhancement of growth in parasitic larvae of ascaris suum: validation of a bioassay. | third-stage larvae of the swine parasitic roundworm, ascaris suum, were grown in stationary multiwell cultures in the presence of synthetic steroid hormones or the hplc fractions of a steroid extract of adult female reproductive tracts to determine the subsequent effect of these compounds on length of 4th-stage larvae. log doses of ecdysone, 20-hydroxyecdysone, progesterone, and makisterone standards, from 50 pg/ml to 500 ng/ml, were incubated with larvae for 1 day in rpmi-1640 supplemented with ... | 1985 | 3973553 |
| intestinal obstruction due to ascaris lumbricoides mimicking intussusception. | two children were admitted for clinical and radiologic signs of small-bowel obstruction. examination revealed an abdominal mass that was suspected of being a mass of intussusception. bowel obstruction caused by ascaris lumbricoides was found at surgery. the laboratory, radiologic, and surgical findings are presented with a short review of the literature with emphasis on diagnosis, incidence, complications, and treatment. | 1985 | 3979231 |
| airway responses to aerosolized leukotriene d4 (ltd4) in normal and ascaris reactor primates. | normal and ascaris reactor primates were compared for their bronchial pulmonary response to aerosolized leukotriene d4 (ltd4). when 10 micrograms/ml ltd4 was aerosolized (total amount delivered to endotracheal tube was 1.0 micrograms) into the lungs of 6 normal primates, a small increase in total lung resistance (rl) was noted (4.4 +/- 4.5% increase, in 19 separate challenges). however, a larger effect was seen in compliance (27.6 +/- 15.8% decrease, n = 19). ascaris reactors (n=4) demonstrated ... | 1985 | 3983410 |
| purification and characterization of the 2-methyl branched-chain acyl-coa dehydrogenase, an enzyme involved in nadh-dependent enoyl-coa reduction in anaerobic mitochondria of the nematode, ascaris suum. | the 2-methyl branched-chain acyl-coa dehydrogenase was purified to homogeneity from mitochondria of the parasitic nematode, ascaris suum. the native molecular weight of the enzyme was estimated to be 170,000 by gel filtration. the enzyme migrated as a single protein band with mr = 42,500 during sodium dodecyl sulfate-polyacrylamide gel electrophoresis suggesting that the enzyme is a tetramer composed of identical subunits. the enzyme exhibited absorbance maxima at 272, 375, and 452 with a ratio ... | 1985 | 3988734 |
| radiographic plain film and ct findings in lipoid pneumonia in infants following aspiration of mineral oil used in the treatment of partial small bowel obstruction by ascaris lumbricoides. | four children developed lipoid pneumonia following ingestion of mineral oil for the treatment of partial small bowel obstruction by ascaris lumbricoides whorl. ct of the chest showed negative hounsfield numbers which may prove useful in diagnosis. | 1985 | 3991256 |
| ascaris lumbricoides in canada: a reply to d.a. denham. | 1985 | 3992639 | |
| eosinophilia, mast cell hyperplasia and antibody production in rats following an intraperitoneal injection of ascaris cuticle including in-vitro studies of immune eosinophil granule lysis. | a single intraperitoneal injection of ascaris cuticle caused a local eosinophilia with peak levels at 2 wk after injection. mast cells reduced in number and size at 1 wk were found in increased numbers at 3 wk. injection of a collagen-poor fraction of cuticle known as "cuticlin" resulted in a diminished eosinophil and mast cell response compared with injection of whole cuticle. precipitating antibodies to soluble ascaris cuticle collagen were detected in the serum and peritoneal fluid from day 5 ... | 1985 | 4000708 |
| the effect of continuous in-feed medication with thiophanate on ascaris suum and oesophagostomum spp. egg output in young pigs. | the full potential of anthelmintics now available for single dose treatment is not achieved because the devising system for worm control in piglets/weaners is not efficiently applicable in practice. therefore an in-feed medication programme for growing young pigs, allowing only one feed lot to be handled by the farmer, was tested in two studies. study a feed containing 0.0225% thiophanate was continuously fed almost ad lib. to piglets from birth right up to about 25 kg body weight when ready for ... | 1985 | 4000918 |
| population distribution of trichuris trichiura in a community of jamaican children. | the trichuris trichiura worm burdens of 23 children living in a place-of-safety in kingston, jamaica, were assessed by stool collection for more than five days after treatment with mebendazole. this procedure was repeated after a seven-month period of natural re-infection. for both collections the maximum rate of worm expulsion was achieved on the fourth day after starting treatment. the worm population distributions were overdispersed and well described by the negative binomial probability mode ... | 1985 | 4002293 |
| taenia hydatigena: a cause of persistent liver condemnations in lambs. | a problem of high levels of liver condemnations which had affected bought-in lambs fattened on a north yorkshire farm for several years was investigated. because the farmer spread pig slurry on the land, migrating ascaris suum larvae were initially suspected as a cause but the investigation eliminated this possibility. migrating taenia hydatigena larvae were found in tissue sections and isolated from livers. a combination of parasitological and serological evidence using oncospheral antigen in a ... | 1985 | 4002589 |
| immunization of pigs against ascaris suum by sequential experimental infections terminated with fenbendazole during larval migration. | three experimental infections of weaning pigs with 2000 embryonated ascaris suum eggs each, 11 days apart, followed each time by fenbendazole treatment, produced a significant host response when compared with similar infected or uninfected control pigs as assessed by response to a subsequent challenge with 100 embryonated a. suum eggs. the response elicited from pigs treated with fenbendazole on either 2, 3, and 4 days or, 6, 7, and 8 days after each experimental infection was expressed as a red ... | 1985 | 4002602 |
| penetration of ovicidal fungi through altered egg-shells of ascaris suum. | ovicidal activity was studied in microscopic fungi penetrating into and destroying eggs of geohelminths surviving in the soil. the character of penetration was compared in eggs obtained mechanically with those obtained by means of a chemical process. a total of 13 strains of ovicidal fungi of 4 species were studied. the shells of eggs obtained by the chemical process were so altered that under the same conditions they were attacked and penetrated by the fungi much more than the eggs obtained by ... | 1985 | 4007704 |
| induction and down-regulation of conjunctival type-i hypersensitivity reactions in guinea pigs sensitized topically with fluoresceinyl ovalbumin. | type-i hypersensitivity reactions were induced in guinea pigs by repeated topical/conjunctival application of fluoresceinyl ovalbumin (fl-oa). the ocular reactivity in early responding animals was maximal between 16 and 25 days and decreased exponentially thereafter. desensitized eyes responded minimally to compound 48/80 but maximally to histamine. unilateral sensitization and challenge with fl-oa produced desensitization of the immunized eye, but the reactivity of the contralateral eye persist ... | 1985 | 4011127 |
| sodium azide preservation of faecal specimens for kato analysis. | the modified kato technique has the advantages of reproducibility, simplicity and economy: the disadvantage is that it cannot be used in conjunction with traditional faecal preservatives. sodium azide has been evaluated as a preservative for human faeces for subsequent kato analysis. more than 400 faecal samples (from normal and malnourished children, and from mixed-age participants in a field survey of the turks and caicos islands) were each mixed with 2-5 mg of sodium azide powder and stored i ... | 1985 | 4011316 |
| [parasite egg development during methane fermentation]. | investigations were carried out on the development of the most frequently encountered parasitic diseases in farm animals raised under industrial conditions. the parasite eggs were obtained from great numbers of animals with fascioliasis, dicrocoeliasis, ascaridiasis, and paramphistomum infection, etc., and were mixed with fecal homogenate in a lagoon of a fermentor in the conditions of methane fermentation. it was found that the parasite eggs in such conditions retained their vitality in a state ... | 1985 | 4013079 |
| [met-enkephalin-arg-gly-leu-like immunoreactivity-containing nerve fibers and cell bodies in the abdominal sympathetic ganglia of the rat--an immunohistochemical study]. | the occurrence and localization of met-enkephalin-arg-gly-leu (met-enk-arg-gly-leu)-like immunoreactivity in the lumbar paravertebral ganglion and the superior mesenteric ganglion in the rat were investigated by immunocytochemistry. colchicine was employed as an axonal flow blocker to accumulate met-enk-arg-gly-leu in the nerve cell bodies. the met-enk-arg-gly-leu serum (r 0171) was produced by immunizing a mixed breed female rabbit with synthetic met-enk-arg-gly-leu conjugated to ascaris protei ... | 1985 | 4018310 |
| localization of choline acetyltransferase within identified motoneurons of the nematode ascaris. | choline acetyltransferase (cat) activity has been measured in the nematode ascaris lumbricoides. strips of hypodermal tissue which contained branches of single identified motoneurons (stretton, a.o.w., r.m. fishpool, e. southgate, j.e. donmoyer, j.p. walrond, and i.s. kass (1978) proc. natl. acad. sci. u.s.a. 75: 3493-3497) as well as control strips containing no neural tissue were assayed. in strips of hypodermis which contained branches of excitatory motoneurons (classes de1, de2, and de3), ca ... | 1985 | 4020429 |
| late pulmonary response in guinea pigs after ascaris challenge. | respiratory resistance of guinea pigs immunized with ascaris suum was measured over 6 hr after aerosol challenge of the allergen by use of the oscillation method. these animals showed a biphasic pulmonary response to the aerosol challenge with ascaris suum. histological analysis of these animals revealed a narrowing of bronchial lumen, peribronchial edema and neutrophil-rich mucous in bronchial lumen at the late pulmonary response. | 1985 | 4024080 |
| [soil properties and the etiology of ascariasis in humans]. | 1985 | 4024570 | |
| diethylpyrocarbonate inactivation of nad-malic enzyme from ascaris suum. | treatment with diethylpyrocarbonate results in a first-order loss of the malate oxidative decarboxylase activity of nad-malic enzyme. first-order plots are biphasic, with about 40-50% activity loss in the first phase. the inactivation process is not saturable, and the second-order rate constant is 4.7 m-1 s-1. malate (250 mm) provides complete protection against inactivation (as measured by a decrease in the inactivation rate), and less malate is required with mg2+ present. partial protection (5 ... | 1985 | 4026323 |
| albendazole in the treatment of intestinal helminthiasis in children. | a single dose of 2% albendazole suspension (400 mg in 20 ml) was administered to 77 patients (42 males and 35 females), ages ranging between 2 to 12 years, with helminthic infections. ascariasis was the most prevalent infection. patients were followed-up for 3 weeks. the results showed that albendazole was highly effective against ascaris lumbricoides, ancylostoma duodenale and enterobius vermicularis. significant improvement was also observed in patients having infections due to trichuris trich ... | 1985 | 4028809 |
| ascaris suum: role of ecdysteroids in molting. | three studies were conducted to examine the function of ecdysteroids in the development of parasitic nematodes. ecdysone and 20-hydroxyecdysone were extracted, separated chromatographically, and measured in the reproductive tracts of adult female ascaris suum. perienteric fluid and the body wall did not contain measurable levels of these steroids. levels of 20-hydroxyecdysone were correlated with the third and fourth molts of larvae grown in vitro from the third stage. in a bioassay, addition of ... | 1985 | 4029350 |
| ascaris suum: protective immunity in pigs immunized with products from eggs and larvae. | parasite products were collected at three distinct phases of development of ascaris suum, and their immunogenicity was determined after injection into rabbits and pigs. products were derived from (1) the hatching fluid of infective eggs; (2) the conditioned medium of 2nd-stage larvae that developed to 3rd stage in vitro in defined medium; and (3) the conditioned medium of 3rd-stage larvae that developed to 4th stage in vitro in defined medium. protein profiles from these three preparations, sepa ... | 1985 | 4029352 |
| growth and form of the fourth-stage larvae and early adults of ascaris suum goeze, 1782 (nematoda: ascaridoidea) developing in pigs. | the fourth-stage larvae and adults of ascaris suum were studied as they developed in the pig intestine from 11 to 22 days after infection. this is a period of rapid growth, in which both sexes increase approximately ten-fold in body length. further examination of females showed the length increase to be positively allometric with respect to body diameter. the genital primordium in early fourth stage is at the same relative position along the length of the body as it is in the newly hatched larva ... | 1985 | 4031452 |
| parallel induction of ige-mediated ascaris antigen airway responses and increased carbachol airway reactivity in rhesus monkeys by infection with ascaris suum. | in continuation of studies of four rhesus monkeys infected with ascaris suum (j lab clin med 101:864-872, 1983), we report the duration of ige-mediated skin reactivity and airway responses to ascaris antigen from 15 weeks to longer than 2.8 years. a second group of four rhesus monkeys was infected with a. suum ova after determination of the threshold of airway reactivity to carbachol. evaluation of these animals confirmed the initial results of the first group of animals studied in relation to i ... | 1985 | 4031630 |
| [fatal pulmonary infection caused by lagochilascaris sp., probably lagochilascaris minor leiper, 1909]. | 1985 | 4035207 | |
| egg count variability and sensitivity of a thin smear technique for the diagnosis of schistosoma mansoni. | variation in daily egg counts, and in counts for samples of the same stool, was investigated in children with schistosoma mansoni and ascaris lumbricoides infections, using a thin smear technique. the results indicated that counts vary according to the stool consistency; drier stools from the same person producing up to seven times greater counts than wet ones. the sensitivity of the technique was tested in schoolchildren living in an endemic s. mansoni area, and found to detect all infections w ... | 1985 | 4035739 |
| the prevalence of intestinal parasites in two suburbs of kinshasa (zaire) and their relation to domestic water supplies. | the prevalence of common intestinal nematodes (ascaris, trichuris and hookworms) and protozoa (entamoeba coli, e. histolytica, giardia, trichomonas) was compared in two suburbs of kinshasa, one provided with piped water and the other one with wells. pit latrines were used in both places. no significant differences were observed for the worms, but the prevalence of the four common protozoa was approximately twice as high in the community without piped water supply. it is concluded that providing ... | 1985 | 4035775 |
| functional and biochemical characterization of immunologically derived equine platelet-activating factor. | antigen-specific challenge of equine leukocytes induced the non-lytic release of a platelet-activating factor in vitro. the equine platelet-activating factor stimulated the release of serotonin from equine platelets in a dose-responsive manner, independent of the presence of cyclo-oxygenase pathway inhibitors such as indomethacin. rabbit platelets were also responsive to equine platelet-activating factor. the release of equine platelet-activating factor was a rapid reaction with near maximal sec ... | 1985 | 4035942 |
| [destruction of helminth eggs in sewage sludge purification plants]. | 1985 | 4038816 | |
| ovicidal effects of albendazole in human ascariasis, ancylostomiasis and trichuriasis. | albendazole, a broad spectrum anthelmintic, was administered as a 400 mg single dose to 20 patients harbouring ascaris (ten cases), hookworms (four cases each of ancylostoma duodenale and necator americanus) and trichuriasis (ten cases). faeces were obtained before treatment and during the following five days. coprocultures were made for 90 days for ascaris and trichuris eggs, hookworm eggs were cultured by the harada-mori technique for at least eight days. albendazole was ovicidal against all f ... | 1985 | 4039128 |
| [search for ovicides among chemical industrial waste products]. | 1985 | 4040207 | |
| enzymes regulating glucosamine 6-phosphate synthesis in the zygote of ascaris suum. | 1985 | 4040895 | |
| reversible inhibition of development and hatching of infective eggs of ascaris lumbricoides var. hominis. | 1985 | 4040967 | |
| synaptic inhibition and cell communication; impairment of cell-to-cell coupling produced by gamma-aminobutyric acid (gaba) in the somatic musculature of ascaris lumbricoides. | the influence of gamma-aminobutyric acid (gaba) (10(-5) m) on the electrical coupling of giant somatic muscle cells of ascaris lumbricoides was investigated. gaba enhanced the resting potential of the cells and abolished the spike activity. the coupling coefficient (v2/v1) was reduced by 58.8% while the input resistance (rin) was decreased by 38.8%. the decline in rin was not related to unlinearity of the current-voltage relation. as the time constant of cell membrane was reduced by 28.4% by the ... | 1985 | 4042165 |
| [survey of helminthic infections and treatment of taenia species infection among the aborigines in chien-shih district, hsin-chu county, northern taiwan]. | six hundred and sixteen out of 770 (80%) aborigines examined were found to be infected with intestinal helminthes. a total of 7 species of parasites were detected with the formalin-ether concentration technique. the infection rate of ascaris lumbricoides was 77.1%, trichuris trichiura 28.8%, taenia sp. 18.4%, enterobius vermicularis 1.6%, and there was one case each of hookworm, hymenolepis nana and h. diminuta infections. infection rate was slightly higher among females (81.3%) than males (78.9 ... | 1985 | 4042757 |
| aminopeptidase inhibitor from ascaris suum. | the correlation of aminopeptidase activity in the homogenate and perienteric fluid from ascaris suum to the concentration of the studied fluids was assessed. the obtained non-linear correlations were interpreted as a result of the presence of the inhibitor. in further experiments, it was demonstrated that aminopeptidase inhibitor is present in the homogenate and perienteric fluid from a. suum. the effect of this inhibitor was studied using different substrates. the effects of the inhibitor on am ... | 1985 | 4043864 |
| epidemic ascariasis--evidence of transmission by imported vegetables. | this paper describes a local ascaris lumbricoides epidemic with special reference to the factors giving rise to its breaking out. ten of the 12 patients were children, and six patients were definitely diagnosed for ascaris lumbricoides worms in their faeces in addition to worm eggs. the epidemic was probably due to imported vegetables and took place in the early winter 1982 and 1983. | 1985 | 4059714 |
| [helminth infestations in non-european travellers--results of stool examinations 1973-1981 in the district of leipzig (east germany)]. | infestations with helminths of non-european travellers--results of stool examinations 1973-1981 in the region of leipzig (gdr). in the years 1973-1981 6,530 foreigners from 98 non-european nations were examined helminthologically by means of 15,288 koproovoscopic samples of stool. altogether 52% of the examined persons were found to be infected with helminths. 15 species or groups of species were found. 38% of the examined persons were infested with trichuris trichiura, 21% with "ancylostomatida ... | 1985 | 4061957 |
| [ascaris lumbricoides: pathological anatomy]. | 1985 | 4062382 | |
| municipal sewage sludge application on ohio farms: tissue metal residues and infections. | transmission of infectious agents and translocation of cd, cu, pb, and zn from anaerobically digested sludge to the tissues of farm animals grazing on pastures to which sludge was applied (2-10 metric tons per hectare) were studied on eight farms. no significant health risk associated with the possible presence in sludge of salmonella spp., or of common animal parasites including nematodirus spp., strongylus spp., strongyloides spp., trichuris spp., eimeria spp., ascaris spp., and ancylostomum s ... | 1985 | 4065082 |
| [capacity for ige antibody production in ask mice]. | the capacity for ige anti body production in ask mice, which are highly sensitivity to anaphylactic shock, was compared with that in c3h and akr mice. three strains of mice were immunized with dnp-ascaris mixed with aluminum hydroxide gel. ige antibody to dnp in the sera was titrated by the rat 48-hour passive cutaneous anaphylaxis test. maximum ige titers of each strain of mice were 1: 2560 in c3h, 1: 1280 in ask and 1: 640 in akr. ige antibody was detected in the sera until 170 days in c3h, 29 ... | 1985 | 4065216 |
| effects of leukotriene d4 on mucociliary and respiratory function in allergic and nonallergic sheep. | we determined the effect of aerosol challenge with leukotriene d4 (ltd4) on specific lung resistance (srl) and tracheal mucous velocity (tmv) in conscious sheep with (allergic) and without (nonallergic) ascaris suum hypersensitivity. in allergic sheep ltd4 in concentrations of 50, 100, and 150 micrograms/ml produced dose-dependent increases in mean srl by 44 (p = ns), 154 (p less than 0.05), and 233% (p less than 0.05), respectively. the increase in srl produced by 150 micrograms/ml ltd4 was pre ... | 1985 | 4066571 |
| nutritional requirement of folic acid in ascaris lumbricoides & the role of cuticle & gut in its absorption. | 1985 | 4077174 | |
| the survival of parasite eggs throughout the soil profile. | an experiment using lysimeters suggested that the eggs of taenia saginata and ascaris lumbricoides survive for only a short time when applied to pasture in sewage sludge. however, a subsequent experiment which followed the survival of eggs throughout the soil profile demonstrated that some t. saginata eggs could still be found at 200 days on the soil surface, and that survival increased down the profile. rainfall is shown to be able to wash eggs into the soil where they may be afforded protectio ... | 1985 | 4080421 |
| the induction and kinetics of an anti-dnp ige response in dogs. | twenty-eight dogs immunized to dinitrophenol-ascaris (dnp-asc) at birth and then three times at two week intervals produced serum anti-dnp antibody. the igm response was detected one week after primary immunization and lasted for up to five weeks. the ige and igg antibody response in general was not present until week three but persisted through the immunization schedule. although variation in the level and duration of the antibody response was detected between individual dogs, each dog did have ... | 1985 | 4082475 |
| [pharmacological receptors of ascaris lumbricoides suis l]. | 1985 | 4082594 | |
| ultrastructure of eggs of ascaris lumbricoides linnaeus, 1758. i. egg-shells. | under the light microscope the chitin-protein layer of egg-shells in ascarids appears to be a regular, hyaline and nonstructural layer of 1.5 to 2.00 microns in thickness. the outer uterine layer is usually removed during the preparation. the lipid (ascaroside) layer covers the inner surface of the chitinous layer and seems to be irregularly undulated and regularly thick over the whole surface, with the thickness up to 1 micron. in electron micrographs the fibrous structure of the lipid layer is ... | 1985 | 4085927 |
| intestinal parasites in kampuchea, takeo province. | fresh stool samples obtained from 1407 adult patients who sought treatment in takeo province hospital and 332 takeo preschool and school-age children from 3 to 18 years of age were examined for the presence of intestinal parasites using the technique of native preparation and the flotation method of faust with subsequent staining with lugol solution to demonstrate cysts. in hospital patients, a total of 13 protozoan and 9 helminth species were diagnosed. the prevalence of entamoeba histolytica ( ... | 1985 | 4086816 |
| tumoral form of ascariasis: report of a case. | the authors report a case of a tumoral form of ascariasis in a 7-year-old boy, simulating a benign neoplasm. microscopic examination revealed a marked granulomatous inflammatory reaction associated with dense fibroblastic proliferation and abscess formation around viable, embryonated ascaris lumbricoides eggs. pathogenesis of this rare clinical form of ascariasis is discussed. | 1985 | 4087328 |
| [device for counting helminth eggs by kato's thick smear]. | 1985 | 4088144 | |
| biosynthesis of lipids during embryogenesis of ascaris lumbricoides eggs. | alteration in lipid metabolism of ascaris lumbricoides eggs during development in either air or nitrogen gas was studied using acetate-1-14c and labeled fatty acids. it is thought that formation of 14c-lipids and 14c-palmitoleate from acetate-1-14c and palmitate-1-14c in developing eggs may be influenced by the concentration of molecular oxygen in the medium. acetate-1-14c was incorporated into palmitate, palmitoleate and unsaturated 18-carbon acid of fatty acids in the eggs, but the incorporati ... | 1985 | 4089865 |