Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| the importance of c5 and the role of the alternative complement pathway in leukocyte chemotaxis induced in vivo and in vitro by bacteroides fragilis lipopolysaccharide. | chambers implanted subcutaneously in c5 normal (c5 n) and c5 deficient (c5 d) mice were used to examine the migration of polymorphonuclear leukocytes (pmns) into the wound chamber fluid in response to injected bacteroides fragilis lipopolysaccharide (lps). the difference in pmn migration was highly significant between the two mouse strains, the c5 d mice showing no initial, but a low, delayed migration. the results from the study indicated that chemotaxis plays a major role in the accumulation o ... | 1978 | 696326 |
| anaerobic and aerobic bacteriology in head and neck cancer surgery. | a prospective study of wound infections following major head and neck cancer surgery was undertaken to define a rational approach to trials of antibiotic prophylaxis and initial therapy of these infections. preoperative aerobic cultures were taken from the planned site of skin incision and from the oropharynx. both aerobic and anaerobic cultures were obtained from all wound infections. patients receiving prophylactic antibiotics were excluded from the study. the data indicate that preoperative c ... | 1978 | 697638 |
| participation of immunoglobulin and the alternative complement pathway in opsonization of bacteroides fragilis and bacteroides thetaiotaomicron. | studies were conducted to determine the requirements for immunoglobulin and complement for opsonization of bacteroides fragilis and bacteroides thetaiotaomicron. the ability of human sera depleted of immunoglobulin or complement components to promote phagocytosis and intracellular killing of the strains of bacteroides by human leukocytes was measured in vitro under anaerobic conditions. neither hypogammaglobulinemic sera nor pooled normal human serum (pnhs) heated at 56 c for 30 min supported ph ... | 1978 | 701850 |
| [asporogenic anaerobic bacterial cells isolated from extrahepatic abscesses and human breast tumor]. | 1978 | 704449 | |
| inactivation of metronidazole by anaerobic and aerobic bacteria. | the rate of inactivation of metronidazole in vitro was determined during the course of time-kill curves against anaerobic and aerobic bacteria in the stationary phase of growth. metronidazole at a concentration of 10 mug/ml, as measured by bioassay, was rapidly inactivated in broth culture by susceptible anaerobic bacteria (minimum bactericidal concentration </= 3 mug/ml), and this correlated closely with its bactericidal activity. in contrast, the drug was neither inactivated nor had any bacter ... | 1978 | 708015 |
| susceptibility of anaerobic bacteria to sulfamethoxazole/trimethoprim and routine susceptibility testing. | the minimal inhibitory concentrations (mics) of sulfamethoxazole and trimethoprim against 144 strains of obligately anaerobic bacteria were determined on diagnostic sensitivity test agar (oxoid) or in prereduced diagnostic sensitivity test broth, both supplemented with sodium pyruvate (1 mg/ml), hemin (5 mug/ml), and vitamin k(1) (1 mug/ml). fifty-eight percent of the strains were susceptible to sulfamethoxazole alone (mic </= 16 mug/ml), only 12% were susceptible to trimethoprim alone (mic </= ... | 1978 | 708016 |
| bacteroides fragilis meningitis in a neonate successfully treated with metronidazole. | 1978 | 712483 | |
| comparative susceptibilities of anaerobic bacteria to metronidazole, ornidazole, and sc-28538. | the susceptibilities of 284 anaerobic bacteria, including 55 strains of the bacteroides fragilis group, were determined by an agar dilution technique to metronidazole and two newer nitroimidazoles, ornidazole and sc-28538. all three agents showed marked in vitro activity against virtually all anaerobic bacteria tested. at concentrations </=1 mug/ml, sc-28538 was significantly more active than either metronidazole or ornidazole. at concentrations of >1 mug/ml, the activities of all three agents w ... | 1978 | 718156 |
| ticarcillin disodium in anaerobic infections. | twenty-five patients were treated with ticarcillin disodium, 18 of whom had anaerobic infections that included pleuropulmonary infections (seven), mandibular osteomyelitis (four), perirectal abscess (two), sepsis, primary site unknown (one), liver abscess (one), pelvic abscess (one), decubitus ulcer (one), and synergistic gangrene (one). seven had no anaerobic infections. three had anaerobic septicemia. culture results included anaerobes: peptococci (ten), peptostreptococci (ten), bacteroides fr ... | 1978 | 718311 |
| experimental bacteroides fragilis keratitis. | to determine the corneal pathogenicity of certain anaerobic bacteria, bacteroides fragilis keratitis was induced in rabbits by the intrastromal inoculation of 10' viable organisms. all eyes inoculated developed central abscesses within 24 hours. abscesses persisted and became vascularized in two of three eyes that were observed for two weeks, as demonstrated both clinically and histologically. eyes inoculated superficially with live organisms or intrastromally with solutions of dead organisms di ... | 1978 | 718520 |
| evaluation of microdilution trays (sensititre) for antimicrobial susceptibility testing of bacteroides fragilis. | microdilution trays (sensititre) for antimicrobial susceptibility testing of bacteroides fragilis has been compared for accuracy with the standard agar dilution method. the microtrays were found to be reliable for all antimicrobials tested (benzylpenicillin, clindamycin, doxycycline, chloramphenicol, fusidic acid, cefoxitin, and cephalotin) but not for metronidazole. | 1978 | 723780 |
| comparative in vitro activity of newer cephalosporins against anaerobic bacteria. | the in vitro susceptibilities of 408 recent clinical isolates of anaerobic bacteria against cefaclor, cephalexin, cephalothin, cefazolin, cefamandole, and cefoxitin were compared by an agar dilution technique. against gram-positive bacteria, especially peptococci, peptostreptococci, and propionibacteria, cephalexin and cefaclor were significantly less active than cephalothin (p < 0.05). cephalexin was also less active than cephalothin against clostridia and lactobacillus (p < 0.05). against gram ... | 1978 | 727759 |
| effect of antibiotics on the prevention of experimental bacteroides fragilis endocarditis. | the relative efficacy of single doses of antibiotics in modifying the development of bacteroides fragilis subsp. fragilis endocarditis was studied in an experimental model. antibiotics were administered 0.5 h before intravenous injection of b. fragilis subsp. fragilis into rabbits prepared by insertion of a polyethylene catheter into the left side of the heart; 48 h later, intracardiac vegetations were excised and cultured anaerobically. b. fragilis was recovered from 92% of untreated animals. a ... | 1978 | 727764 |
| anaerobic bacteria: evaluation of disc susceptibility to four cephalosporins. | the disc diffusion technique was evaluated with 178 strains of anaerobes and four cephalosporins (cephalothin, cefamandole, cefazolin and cefoxitin). good correlation in results was found in comparison with the agar dilution technique (p less than 0.001) with the exception of cefamandole and cefazolin against anaerobic cocci (p greater than 0.05). choosing a breakpoint of 8 microgram/ml for distinguishing susceptible and resistant strains, we determined corresponding incubation, the rate of erro ... | 1978 | 730395 |
| factors affecting production of catalase by bacteroides. | several variables affected the production of catalase by members of the "bacteroides fragilis group" of anaerobic bacteria. both media yielded higher catalase levels than the respective agar media. addition of hemin to media after autoclave sterilization, rather than before, significantly increased production of catalase. both of these variables could be related to the available hemin concentration present in the medium being tested. significantly higher amounts of hemin were required for catal ... | 1978 | 730827 |
| differentiation of bacteroides fragilis species by gas chromatographic detection of phenylacetic acid. | of 382 strains tested, 261 strains of the species bacteroides fragilis, b. thetaiotaomicron, b. ovatus, and b. distasonis produced phenylacetic acid; the remaining strains, belonging exclusively to the species b. vulgatus, failed to do so. this differentiation characteristic may be useful in routine clinical bacteriology. | 1978 | 730830 |
| [peritoneal drainage without antibiotics (author's transl)]. | the mortality of generalized peritonitis in serious. the drainage of the peritoneal cavity for diffuse peritonitis is essential but difficult, and it should be combined with peritoneal lavage. the drainage system must be properly adapted to the intraperitoneal liquid circulation. the local use of antibiotics is not indicated. systemic administration is obvious, because in about 80% of cases, it is an anaerobic infection with bacteroides fragilis, a dreadfully tough organism, which impairs the fu ... | 1978 | 732452 |
| activity of sulfamethoxazole trimethoprim against bacteroides fragilis. | the author tested parallely 35 bacteroides fragilis strains by the agar diffusion method and disk technique. a notable discrepancy appears between these two procedures. no regression line can be constructe and the inhibition diameter measurement is unable to class the strain in "susceptible" or "resistant". a literature review on this theme shows that the dissociation between these two techniques were more frequent with anaerobic strains than aerobic for smx + tmp as others antibiotics. the mic ... | 1978 | 735555 |
| anaerobic susceptibility tests. evaluation of the stability of antimicrobials in wilkens-chalgren broth and the effect of media prereduction. | the stability of eight antimicrobial agents in wilkens-chalgren broth was evaluated. the activities of only carbenicillin and benzyl penicillin were significantly decreased after storage for eight weeks at--20 degrees c. anaerobic reduction of the susceptibility testing broth prior to inoculation was found to be unnecessary. | 1978 | 738968 |
| diagnosis of bacteroides fragilis infection with counter-immunoelectrophoresis. | in a study of 188 patients and 109 controls, the detection of antibody by counterimmunoelectrophoresis was used as a diagnostic aid in human infections with bacteroides fragilis. it was found that positive results indicated current infection and negative results were not conclusive. the method used was simple, rapid, and easily performed in a routine laboratory, but further work is needed to enhance antigen potency. | 1978 | 739053 |
| serological diagnosis of bacteroides fragilis infections by a complement fixation test. | paired specimens of serum from patients from whom bacteroides fragilis had been isolated were tested by complement fixation against a crude b. fragilis antigen. a high titre or a rise in titre to b. fragilis was obtained in each of five patients with infection after abdominal surgery but in none of 11 patients with postpartum pyrexia nor in nine with vaginitis. | 1978 | 739054 |
| isolation of auxotrophs of bacteroides fragilis. | techniques employing ethane methanesulfonate and modified penicillin enrichment were developed whereby auxotrophs of bacteroides fragilis could be readily isolated. several auxotrophic phenotypes are described. | 1978 | 747821 |
| bacteriology and therapy of lung abscess in children. | the bacteriology and clinical findings of ten pediatric patients with lung abscess are presented. bacteriologic data were based on percutaneous transtracheal aspiration obtained before initiation of antimicrobial therapy. anaerobic bacteria were present in all ten patients; in nine they were mixed with aerobic bacteria. the most frequent isolates were peptostreptococcus (8), peptococcus (5), bacteroides melaninogenicus (6), and bacteroides fragilis (3). the aerobic isolates most frequently recov ... | 1979 | 758385 |
| bacteroides fragilis and hr 756. | 1979 | 762000 | |
| [salmonella infection and host reaction, with special reference to enzymatic and histochemical studies]. | 1975 | 765538 | |
| intracolonic tensions of oxygen and carbon dioxide in germfree, conventional, and gnotobiotic rats. | the relation of intracolonic gaseous tension to fecal microflora was investigated by mass spectrometric measurements of intracolonic o2 and co2 in unanesthetized germfree, conventional, and gnotobiotic rats; ip measurements were obtained in rats whose colons became perforated accidentally; fecal bacterial flora and cecal size were also determined. gnotobiotes were monoassociated with escherichia coli, bacteroides fragilis and staphylococcus epidermidis, and were diassociated with e. coli plus b. ... | 1976 | 766018 |
| infectious morbidity due to bacteroides fragilis in obstetric patients. | the patterns of endogenous bacterial participation, particularly of bacteroides fragilis, in the condition called progressive anaerobic syndrome and their clinical consequences are discussed. b. fragilis is an anaerobe recently resistant to tetracycline, which before 1970, was the drug of choice. presently, clindamycin is the drug of choice for severe bacteroides infections, though diarrheal side effects often interfere with administration; if contraindicated or side effects occur which are in ... | 1976 | 767027 |
| attempted transfer of antibiotic resistance between bacteroides and escherichia coli. | transfer of antibiotic resistance between bacteroides organisms and e. coli in mixed culture under optimal anaerobic conditions was attempted. donor strains used were e. coli with r factors of a number of compatibility groups and bacteroides with unusually high antibiotic resistance. recipient strains included e. coli strains with characteristics favouring conjugal transfer. although control experiments verified that conjugal transfer of derepressed r factors could occur at a high frequency betw ... | 1976 | 768412 |
| isolation and identification of anaerobic bacteria. | anaerobic bacteria make up a predominant part of the normal human flora. adequate specimen collection must avoid contamination with this flora. suitable methods include thoracentesis, transtracheal aspiration, needle and syringe aspiration of closed abscesses, and endocervical aspiration of intrauterine pus. swabs are generally unsuitable. sputum, voided urine, vaginal secretions, and specimens contaminated with feces are not cultured anaerobically. specimens should be transported in an oxygen-f ... | 1976 | 770306 |
| susceptibility of the liver and biliary tract to anaerobic infection in extrahepatic biliary tract obstruction. iii. possible synergistic effect between anaerobic and aerobic bacteria. an experimental study in rabbits. | the pathogenicity of single anaerobic, single aerobic, and mixed anaerobic and aerobic bacterial inocula was studied in 3 groups of 12 rabbits with biliary tract obstruction. b. fragilis, ss. fragilis and e. coli serotype 01: k1: h7 were used. the investigation was made 7 days after bacterial inoculation and included bacteriological studies of the liver and bile as well as studies of liver function and morphology of the liver and biliary tract. inoculation of 10(5)-10(6) e. coli did not cause bi ... | 1976 | 775613 |
| r factor transfer to obligate anaerobes from escherichia coli. | 1976 | 778328 | |
| a modified plate holding system for anaerobic cultures. | a modified plate holding system for anaerobes has been developed which: 1) effectively reduces the volume of oxygen-free gas required, 2) promotes earlier bacterial growth, and 3) monitors the anaerobic atmosphere of the holding vessel and the rate of gas flow. cultures of bacteroides fragilis, clostridium perfringens, c. septicum, fusobacterium nucleatum, peptococcus sp. and propionibacterium sp. were evaluated for optimal growth. all cultures grew as well as or better when preincubated in the ... | 1976 | 782243 |
| bacteriological survey of acute appendicitis in children. | a bacteriological study of 110 emergency appendicectomies is reported. in two-thirds of these the appendix was inflamed or gangrenous, and in 45 cases positive cultures were obtained from swabs taken at operation. bacteroides were found frequently in these swabs and also in those taken from wound infections. although this study is too small to draw any definite conclusions, it is felt that bacteroides should be considered an important pathogen in appendicitis and should be taken into account in ... | 1976 | 782625 |
| anaerobic and aerobic bacteriological studies in biliary tract disease. | thirty-eight patients without biliary tract disease, 68 patients with gallbladder stones or acalculous chronic cholecystitis, 30 patients with common duct obstruction due to stones or strictures, and 28 patients with common duct obstruction due to tumors or chronic pancreatitis were investigated. gallbladder bile or common duct bile was cultured anaerobically and aerobically. anaerobic culture procedures were based on the use of a glove-box and prereduced, anaerobically sterilized media. transpo ... | 1976 | 785585 |
| a trichomonas species in a mixed microbial meningitis. | 1976 | 787565 | |
| anaerobic infections: diagnosis and treatment. | anaerobic bacteria outnumber aerobic bacteria in normal flora in the oropharynx and gastrointestinal tract. they are important and frequent causes of infection, although they often go unrecognized except in the classic and very distincitve clostridial infections and intoxications-gas gangrene, botulism, and tetanus. although anaerobic infections often originate close to a muscosal surface where anaerobes are part of the normal flora, they may occur anywhere in the body via direct of hematogenous ... | 1976 | 788160 |
| animal models of peritonitis. | a reproducible animal model of peritonitis has been developed. it uses standard animals, standardized cultures of bacteria and simple techniques. use of this model would facilitate comparison of data from workers in this field. the use of small rodents permits the use of comparatively large populations for statistical evaluation. the method is cheap and economic of laboratory space and does not require surgical expertise. | 1976 | 790613 |
| aerobic and anaerobic flora of the cervix during pregnancy and the puerperium. | comparison of species of bacteria isolated from patients with endometritis with species isolated from normal pregnant and nonpregnant women suggests that bacteria causing infections are indigenous to the genital tract. however, complete studies of the flora of pregnant women, especially anaerobic flora, are lacking. aerobic and anaerobic cultures of the endocervix were obtained from women in all trimesters of pregnancy and at three days and six weeks post partum. the incidence of occurrence of e ... | 1976 | 793391 |
| a rapid glutamic decarboxylase test for identification of bacteria. | a simple rapid glutamic decarboxylase test is described. this test was found useful in the identification of escherichia coli, shigella sp., providencia alcalifaciens, clostridium perfringens and bacteroides fragilis. | 1976 | 793504 |
| prophylactic lincomycin in the prevention of wound infection following appendicectomy: a double blind study. | the prophylactic use of a single dose of lincomycin in 100 patients undergoing appendicectomy reduced the incidence of postoperative wound infection from 17 to 6 per cent compared with a similar group of control patients. there was no correlation with the histological finding in the appendix, but patients with perforated appendicitis were excluded from the study. bacteriological examination of the appendix area before surgery showed that bacteroides fragilis and escherichia coli were the organis ... | 1976 | 795496 |
| susceptibility of anaerobic bacteria to carbenicillin, cefoxitin, and related drugs. | the agar dilution technique was used for determination of the bacteriostatic activity of carbenicillin, penicillin g, cefazolin, cephaloridine, cefoxitin, and cephalothin agaomst a variety of anaerobic bacteria. carbenicillin showed a high level of activity at a concentration of smaller than or equal to 100 mug/ml; only five of 123 strains of bacteroides fragilis, one strain of bifidobacterium eriksonii, and one strain of clostridium bifermentans were resistant to a concentration of larger than ... | 1975 | 804023 |
| immune responses in eight patients infected with bacteroides fragilis. | sera from eight patients with either septicemia or pyothorax caused by bacteroides fragilis were assayed for specific antibody by the agglutination, immunofluorescence, and agar gel diffusion techniques. antibodies were detected in the sera of all eight patients by all three serological tests employed; titers as high as 1:160 and 1:320 were detected by the agglutination test and the immunofluorescence technique, respectively, and all patients had precipitating antibody. failure of b. fragilis su ... | 1975 | 805185 |
| factors that may prevent transfer of anti-biotic resistance between gram-negative bacteria in the gut. | antibiotic-resistance transfer between populations of donor and recipient strains of escherichia coli was completely inhibited in broth by dense suspensions of bacteroides fragilis. comparable amounts of inert bacterial matter (for-molised suspensions of e. coli or b. fragilis), or smaller numbers of viable b. fragilis, streptococcus faecalis, staphylococcus albus, neisseria catarrhalis, or solutions of sodium taurocholate or glycocholate were only moderately inhibitory. anaeroboisis had no effe ... | 1975 | 805244 |
| polymicrobial etiology of acute pelvic inflammatory disease. | we studied 204 women with acute pelvic inflammatory disease to delineate further the causes of that illness. gonococci were recovered from 91. gonococcal pili antibody rose or fell significantly in 12 of 18 patients with positive cultures and only two of 19 who had negative cultures and smears for neisseria gonorrhaoea(p smaller than 0.005). n. gonorrhoeae was found in peritoneal exudate from eight of 21 patients with, and none of 33 without, cervical gonococcal infection. among patients with se ... | 1975 | 806017 |
| gram-negative pneumonia in hospitalized patients. | 1975 | 808801 | |
| immunochemical characterization of the outer membrane complex of bacteroides fragilis subspecies fragilis. | the outer membrane of gram-negative bacteria is immunologically the most important structure of the cell because of its accessibility to host defense mechanisms. by electron micrographic studies, it has been shown that bacteroides fragilis has a cell envelope typical of gram-negative bacteria. the outer memberane of this envelope was found to consist of protein, two polysaccharides bound to lipid in various degrees, and loosely bound lipid. the protein component of the outer membrane had a disti ... | 1975 | 810521 |
| combined activity of clindamycin and gentamicin on bacteroides fragilis and other bacteria. | 1975 | 812858 | |
| microbial synergy in experimental intra-abdominal abscess. | intra-abdominal sepsis was studied in wistar rats by using four microbial species: escherichia coli, enterococci, bacteroides fragilis, and fusobacterium varium. these organisms were implanted into the peritoneal cavity singly and in all possible dual combinations. results were evaluated by mortality rates and the incidence of intra-abdominal abscesses on autopsy following sacrifice after 7 days. mortality was restricted to recipients of e. coli, thus implicating coliforms in the acute lethality ... | 1976 | 814099 |
| acute pelvic inflammatory disease: etiology, risk factors and pathogenesis. | it was suggested that several behaviorial factors could be important in allowing mild local symptoms of infection to develop into pid. a localized gonococcal infection may produce an increased vaginal discharge or dysuria. pid results only if several other factors have been operable. loss of the cervical mucus barrier with menstruation appears to be important in allowing bacteria to pass from the cervix in to the uterine cavity. uterine infection may account for the abnormal uterine bleeding see ... | 1976 | 815068 |
| bacteremias associated with routine hemorrhoidectomies. | 1976 | 817876 | |
| effect of sonic treatment on pure cultures and aggregates of bacteria. | pure cultures of a variety of bacteria were treated with ultrasonic energy using a sonic probe. fractions of organisms killed at different sonic energies were calculated, and streptococcus mutans was 600 times more resistant than fusobacterium nucleatum, the most sensitive organism tested. the effects of sonic treatment on aggregates of bacteria were examined, and the results were interpreted as a model of the events that probably occur during the sonic dispersion of dental plaque. | 1976 | 819454 |
| carbohydrate repression of catalase synthesis in bacteroides fragilis. | catalase formation by bacteroides fragilis was immediately stopped upon addition of glucose to a culture growing in peptone medium. each of eight other carbohydrates fermented by the organism also repressed catalase formation. without added carbohydrate, the strains produced relatively large amounts of catalase (25 to 50 u/mg of protein). | 1977 | 830647 |
| suppurative thyroiditis with gas formation due to mixed anaerobic infection. | 1977 | 830929 | |
| quantitative microflora of the vagina. | this study enumerated the predominant vaginal flora in 25 healthy patients: 18 prenatal (six with and 12 without gonorrhea) and seven nonpregnant without gonorrhea. all 25 patients had aerobes and 19 of the 25 had anerobes isolated in titers of greater than or equal to 10(5) colony-forming units (cfu per milliliter). the most frequently isolated microorganism was the lactobacillus (aerobic and anaerobic species) followed by c. vaginale, viridans streptococci, anaerobic gram-positive cocci, and b ... | 1977 | 831488 |
| effect of a high-beef diet on the fecal bacterial flora of humans. | ten human volunteers completed a 4-month diet series consisting of 1 month each of a control diet, a meatless diet, a high-beef diet, and the same control diet. fat and fiber contents were essentially the same in all four diets, but protein content was doubled during the high-beef diet. during the 4th week on each diet, three stool specimens collected from each volunteer were analyzed for chemical composition and content of facultative, aerobic, and anaerobic bacteria. the bacteriological data a ... | 1977 | 832279 |
| sensitivity of bacteroidaceae to fosfomycin. | the sensitivity of 116 strains of bacteroides fragilis and 60 strains of sphaerophorus to fosfomycin was studied. of the 178 strains that were tested, 156 were isolated from pathological products in our department and the remainder came from the following collections: nctc, atcc and the institut fur mikrobiologie of the university of bonn. identification was made morphologically and biochemically in accordance with the scheme which we usually employ and which has previously been published. the s ... | 1977 | 832544 |
| numbers and types of anaerobic bacteria isolated from clinical specimens since 1960. | between 1960 and 1974, 826 specimens, excluding stool, urine, sputum, and blood, yielded 689 (83%) positive cultures, of which 403 (58.5%) contained anaerobic bacteria. this represents 48.8% of the total specimens cultured. isolates from 153 specimens obtained and stocked from 1965 to 1974 were reidentified by current criteria. gram-negative bacilli, primarily bacteroides, were the most frequently isolated anaerobes, being found in 70% of 153 anaerobe-positive specimens and accounting for 42% of ... | 1977 | 833266 |
| antimicrobial effect of amniotic fluid against anaerobic bacteria. | amniotic fluid samples were obtained at term and tested for their antimicrobial effect on anaerobes, peptostreptococcus (ps.) anaerobius, peptococcus (pc.) prevotii, bacteroides (b.) fragilis, and b. coagulans with facultative escherichia (e.) coli serving as control. amniotic fluid had only temporary bacteriostatic effect on pc. prevotii and b. fragilis for 8 to 16 hours. this effect lasted for only 8 hours on ps. anaerobius. on the contrary, the bacteriostatic effect of amniotic fluid was well ... | 1977 | 835621 |
| [bacteriological studies on bacteroides fragilis infections and treatment with clindamycin for intravenous injection (author's transl)]. | 1977 | 839641 | |
| [susceptibility to thiamphenicol and chloramphenicol of anaerobic bacteria (author's transl)]. | the in vitro susceptibility to thiamphenicol and chloramphenicol of 272 anaerobes, most of which were recent clinical isolated, was determined by broth dilution tests, with chloramphenicol, 133 anaerobic gram-negative non-sporing rods (48 bacteroides fragilis, 13 b. thetaiotaomicron, 14 b. oralis, 16 sphaerophorus varius etc.) had mic values of 0.03 through 16 microng/ml. very similar results (mic, 0.06-16 microng/ml) were obtained with thiamphenicol. in concentrations of 4 microng/ml or less ch ... | 1977 | 848218 |
| in vitro activity of ticarcillin against anaerobic bacteria compared with that of carbenicillin and penicillin. | a total of 334 clinical anaerobic isolates were tested in an anaerobic glove box by the agar dilution technique for susceptibility to clinically achievable levels of ticarcillin, carbenicillin, and penicillin. thirty-two micrograms or less of penicillin per milliliter inhibited 91% of all strains, whereas 100 mug of carbenicillin and ticarcillin per ml inhibited 95 and 98%, respectively. a total of 82% (85 strains) of bacteroides were inhibited by penicillin, and 93 and 96% were inhibited by car ... | 1977 | 848931 |
| experimental infections with anaerobic bacteria in mice. | experimental anaerobic infections in mice are reviewed with a description of a model of pure bacteroides fragilis infection. in this experimental situation, b. fragilis produces large subcutaneous abscesses in the groins of mice that can be diagnosed without autopsy. this infection was treated effectively with clindamycin in doses that produced levels of drug in blood similar to those attainable in humans. | 1977 | 850086 |
| introduction. | 1977 | 850087 | |
| comparison of clindamycin and chloramphenicol in treatment of serious infections of the female genital tract. | a study was performed of 102 obstetric-gynecologic patients who were thought to have sepsis or a pelvic abscess. fifty-three of these women received chloramphenicol and 49 received clindamycin. in addition, all patients received penicillin or a similar antibiotic and an aminoglycoside. similar clinical results were observed with the two treatment regimens. in eight of the 49 patients who received clindamycin and in three of 52 patients who received chloramphenicol, use of the drug was discontinu ... | 1977 | 850088 |
| in vitro activity and clinical efficacy of clindamycin in the treatment of infections due to anaerobic bacteria. | clindamycin, rosamicin, josamycin, and metronidazole had similar inhibitory activity against 29 clinical isolates of bacteroides fragilis, i.e., 100% of strains were inhibited by 0.8 microng of metronidazole or josamycin/ml and 100% by 1.6 microng of clindamycin or rosamicin/ml. metronidazole was bactericidal against 97% of the isolates, and clindamycin or rosamicin (in concentrations of 1.6 microng/ml) was bactericidal against 80%. erythromycin and josamicin were the least bactericidal agents i ... | 1977 | 850091 |
| clindamycin for treatment of sepsis caused by decubitus ulcers. | bacteremia was documented in 19 (76%) of 24 patients with sepsis caused solely by decubitus ulcers, persisted in all but two, and was polymicrobial in 10 (42%). obligate anaerobes were isolated from 12 patients (63%) and included bacteroides fragilis in 11 (58%). aerobes, primarily proteus (21%) and staphylococcus (16%), were isolated in nine patients (47%). therapy was judged appropriate when the microbial isolates were susceptible in vitro to the antibiotic used. nineteen patients received cli ... | 1977 | 850093 |
| empiric treatment with clindamycin and gentamicin of suspected sepsis due to anaerobic and aerobic bacteria. | clindamycin and gentamicin were used in combination to treat 107 patients empirically for suspected aerobic-anaerobic sepsis. all patients were seriously ill and required initiation of treatment before results of cultures could be obtained. infections included intraabdominal sepsis, hospital-acquired aspiration pneumonia, and soft tissue infections. exudate cultured from 65 patients showed that the prediction of a mixed aerobic-anaerobic flora was correct in 46 patients (71%). isolates from exud ... | 1977 | 850096 |
| fatty acids in the endotoxins of various bacteroides fragilis subspecies. | 1977 | 851902 | |
| a method for the production of pre-reduced anaerobically sterilized culture media. | 1977 | 853028 | |
| chemotherapy of an experimental bacteroides fragilis infection in mice. | the efficacies of five common antimicrobial agents were determined for a pure bacteroides fragilis infection in mice. therapy was begun 4 h after bacterial injection and given every 8 h thereafter for 5 days. blood levels were determined over an 8-h period for each concentration of antibiotic tested. clindamycin and tetracycline were the most effective in preventing the formation of abscesses. chloramphenicol, penicillin g, and cephalothin were not effective in protecting the mice from infection ... | 1977 | 855998 |
| comparative growth rates of selected anaerobic species in four commonly used broth media. | generations times (g(t)) of selected anaerobic species were compared in four culture media commonly used for anaerobic bacteria to evaluate these media for growing inocula for anaerobic antibiotic susceptibility determinations. twenty-two clinical isolates of bacteroides fragilis, fusobacterium spp., clostridium perfringens, and clostridium spp. were tested in schaedler broth, supplemented lombard-dowell broth, supplemented thioglycolate broth, and supplemented peptone-yeast extract-glucose brot ... | 1977 | 856002 |
| comparative susceptibility of anaerobic bacteria to ticarcillin, cefoxitin, metronidazole, and related antimicrobial agents. | the in vitro antimicrobial activity of two newer agents, ticarcillin and cefoxitin, against 204 recent clinical isolates of anaerobic bacteria was determined by an agar dilution technique, and compared to their related compounds carbenicillin, cephalothin, and penicillin, as well as metronidazole, clindamycin, and chloramphenicol. ticarcillin was similar to carbenicillin, and cefoxitin was more active than cephalothin. at readily achievable blood concentrations of each antimicrobial agent, ticar ... | 1977 | 856019 |
| cefoxitin resistance to beta-lactamase: a major factor for susceptibility of bacteroides fragilis to the antibiotic. | toluene-treated cell suspensions of bacteroides fragilis were used to screen clinical isolates for the production of beta-lactamase. approximately one-third of the isolates possessed considerable cephalosporinase activity. a significant correlation was found between beta-lactamase production and resistance to cephalosporin antibiotics. several isolates were resistant to cefuroxime and cefamandole and produced enzymes capable of hydrolyzing these antibiotics. however, none of the 79 strains teste ... | 1977 | 856025 |
| [in vitro susceptibility of bacteroidaceae to cefoxitin and cephalothin (author's transl)]. | the activity of the new cephamycin c derivatives cefoxitin against 102 clinical isolates of bacteroidaceae (95 bacteroides strains and 7 fusobacterium-sphaerophorus cultures) was determined by tube dilution and standardized agar diffusion tests and compared to that of cephalothin. cefoxitin was more active than cephalothin against 56 bacteroides fragilis strains, 19 bacteroides thetaiota-omicron strains and two bacteroides splanchnicus strains. the difference seemed less pronounced with five bac ... | 1977 | 856727 |
| myocardial abscess complicating healed myocardial infarction. | an isolated myocardial abscess due to bacteroides fragilis developed in the scar of a myocardial infarction. fever, chills and signs of pericarditis were the main clinical features. mild enteritis 1 week prior to the onset of symptoms related to the abscess was the most likely cause of the bacteremia. the diagnosis was established at thoracotomy, performed because of cardiac tamponade. thirteen other cases of isolated bacterial myocardial abscess accompanying myocardial infarction have been repo ... | 1977 | 861868 |
| internal standards for gas chromatographic analysis of metabolic end products from anaerobic bacteria. | 2-methylpentanoic acid and benzoic acid are suggested for use as routine internal standards for gas chromatographic analysis of microbial end products. | 1977 | 869521 |
| experimental bacteroides fragilis endocarditis in rabbits. | a serum-resistant strain of bacterioides fragilis that did not produce heparinase was used to study the characteristics of b. fragilis endocarditis in the rabbit experimental model. the infective dose required to produce endocarditis in 50% of rabbits was significantly lower for rabbits with left-sided intracardiac catheters (log10 6.3 colony-forming units +/- 0.6/ml) as compared with right-sided intracardiac catheters (log10 7.7 colony-forming units +/- 0.8/ml). after 3 days of infection, bacte ... | 1977 | 870433 |
| fatal colitis in a hemophilic patient with inhibitor. | a severe colitis developed in a hemophilic patient following an antibiotic regimen which included clindamycin. a surgical procedure, total hip replacement, had been complicated by the appearance of a powerful factor viii inhibitor and a bacteroides fragilis infection. the resulting bleeding diathesis was successfully managed with the use of an "activated prothrombin complex"; however, the occurrence of colitis following intravenous clindamycin therapy proved to be fatal. clindamycin, like the re ... | 1977 | 870986 |
| development of anaerobic fecal flora in healthy newborn infants. | stool samples from 196 healthy infants less than ten days of age were cultured to delineate bacterial colonization patterns of the intestine. by one week of age, isolation rates of bacteroides fragilis and other anaerobic bacteria in term infants following vaginal delivery and formula feeding approach that of adults. differences in gestational age, type of delivery, and type of feeding are associated with significantly different colonization patterns of anaerobic and aerobic bacteria in the firs ... | 1977 | 874690 |
| synergistic action of erythromycin and cefamandole against bacteroides fragilis subsp. fragilis. | erythromycin and cefamandole have exhibited synergistic activity against eight strains of bacteroides fragilis subsp. fragilis. in concentrations of only 0.25 to 0.5 mug of erythromycin per ml (easily obtainable with oral therapy), less than 0.4 mug (0.015 to 1.0) of cefamandole per ml inhibited the b. fragilis strains. in the presence of the erythromycin, the potency of cefamandole was increased more than 100-fold. on the basis of the mechanism of action of these two antibiotics, the synergism ... | 1977 | 879736 |
| susceptibility of anaerobic bacteria to cofoxitin and related compounds. | cephalothin, cefazolin, cephradine, and cefoxitin inhibited more than 75% of 326 anaerobic bacteria in vitro, but cefoxitin was the most effective against anaerobes in general and bacteroides fragilis in particular. | 1977 | 879743 |
| laminarinase (beta-glucanase) activity in bacteroides from the human colon. | laminarin, a beta(1 leads to 3)-glucan similar to those found in plant cell walls, is fermented by some species of anaerobic bacteria from the human colon. laminarinase (ec 3.2.1.6) and beta-glucosidase (ec 3.2.1.21) activities were determined in strains representing bacteroides thetaiotaomicron, bacteroides distasonis, and an unnamed deoxyribonucleic acid homology group of bacteroides fragilis. in all three species, laminarinase activity was inducible by laminarin and was predominantly cell bou ... | 1977 | 879772 |
| cefuroxime, a new parenteral cephalosporin: collaborative in vitro susceptibility comparison with cephalothin against 5,887 clinical bacterial isolates. | cefuroxime, a new parenteral cephalosporin was compared with cephalothin by broth microdilution susceptibility testing against 5,887 routine clinical bacterial isolates in four large clinical laboratories. the minimal inhibitory concentrations (mics) of cefuroxime against the enterobacteriaceae were consistently lower than those of cephalothin. this was most striking among the enterobacter species, which were generally susceptible to cefuroxime (mic </= 8 mug/ml), but resistant to cephalothin. s ... | 1977 | 883818 |
| the capsular polysaccharide of bacteroides fragilis as a virulence factor: comparison of the pathogenic potential of encapsulated and unencapsulated strains. | the pathogenic potentials of encapsulated and unencapsulated strains of bacteroides fragilis were compared by use of a rat model of intraabdominal sepsis. implantation of encapsulated b. fragilis alone resulted in abscesses in most recipients, whereas unencapsulated strains seldom produced this effect unless they were combined with another organism. implants of heat-killed, encapsulated b. fragilis also resulted in abscess formation. subsequent experiments suggested that the abscess-potentiating ... | 1977 | 886206 |
| [necrosing postoperative enteritis with septicemia due to bacteroides fragilis (ristella)]. | 1977 | 887393 | |
| bl-s786, a new parenteral cephalosporin. i. a collaborative in vitro susceptibility comparison to cephalothin against 5,762 clinical bacterial isolates. | the in vitro activity of compound bl-s786 was compared with that of cephalothin against 5,762 clinical isolates by the microdilution broth method. bl-s786 demonstrated a broader spectrum and a significantly lower mic against the enterobacteriaceae. although greater susceptibility to bl-s786 than to cephalothin was exhibited by serratia marcescens, proteus morganii and proteus vulgaris, these three species were generally resistant to both drugs. by contrast, the staphylococci were significantly m ... | 1977 | 893226 |
| hydrogenase activity and the h2-fumarate electron transport system in bacteroides fragilis. | hydrogenase activity and the h(2)-fumarate electron transport system in a carbohydrate-fermenting obligate anaerobe, bacteroides fragilis, were investigated. in both whole cells and cell extracts, hydrogenase activity was demonstrated with methylene blue, benzyl viologen, flavin mononucleotide, or flavin adenine dinucleotide as the electron acceptor. a catalytic quantity of benzyl viologen or ferredoxin from clostridium pasteurianum was required to reduce nicotinamide adenine dinucleotide or nic ... | 1977 | 893348 |
| bacteroides in pelvic abscesses. | 1977 | 895814 | |
| [treatment of meningitis caused by bacteroides fragilis with injections of ornidazole]. | 1977 | 896422 | |
| [isolation of bacteroides fragilis from the appendix in a case of appendicitis]. | 1977 | 896576 | |
| bacteriology of cholesteatoma: clinical significance. | 1977 | 898521 | |
| bs ii lectin: a second hemagglutinin isolated from bandeiraea simplicifolia seeds with affinity for type iii polyagglutinable red cells. | bs ii lectin, a second hemagglutinin isolated from bandeiraea simplicifolia seeds, agglutinated the red cells from 11 patients manifesting the 'acquired b' antigen phenomenon. the results of serological studies indicate that this lectin has specificity for the type iii polyagglutinable receptors rather than for the 'b-like' antigens present on 'acquired b' red cells. two other blood samples which did not possess 'acquired b' antigens were also found to react with bs ii lectin. both of these samp ... | 1977 | 898840 |
| [increase of anaerobic infections. prevalence of bacteroides. apropos of 17 cases in abdominal surgery]. | seventeen cases of anaerobic infections in abdominal surgery are reported. predominance of bacteroides is evident (9/17), especially bacteroides fragilis. the clinical manifestations of bacteroides infections are severe: 7 septicemias and 2 parietal infections, being the cause of the death in four patients. bacteroides infection develops preferently in an old patient, with severe disease, in colic surgery especially in emergency. bacteroides are characterized by their polyresistance to antibioti ... | 1977 | 900536 |
| bacteroides fragilis infections of the urinary tract. | 1977 | 903332 | |
| susceptibility bacteroides fragilis to fusidic acid. | 1977 | 903333 | |
| [appearance of metronidazole resistance in bacteroides fragilis]. | 1977 | 905136 | |
| the cephalosporins. | cephalosporin antibiotics are bactericidal against most gram-positive cocci and many gram-negative bacilli of clinical importance. they are relatively nontoxic but share with penicillins a tendency to elicit hypersensitivity reactions. they are indicated in certain instances for treatment of infections in patients with penicillin allergy and are frequently chosen as one of the agents in an empiric program in life-threatening infections. cephalosporins should not be used in infections caused by g ... | 1977 | 909313 |
| [bacteroides fragilis septicemia during rheumatoid arthritis]. | 1977 | 909745 | |
| in vitro activity of five oral cephalosporins against anaerobic pathogenic bacteria. | the in vitro inhibitory activities of cefaclor and and cefatrizine, two new orally absorbed cephalosporin antibiotics, against 44 isolates of anaerobic pathogenic bacteria were measured using the agar dilution procedure of the world health organization-international collaborative study. tests also were performed with cephalexin, cephaloglycin, and cephadrine, as well as with the parenteral cephamycin antibiotic cefoxitin. cefoxitin was the most active antibiotic and inhibited the majority of iso ... | 1977 | 915342 |
| [evaluation of the disc-plate method in bacteroides fragilis]. | 1977 | 918321 |