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[features of the clinico-roentgenologic picture of acute pneumonia in chronic alcoholics]. 20133705450
colonic carcinoma metastasizing to the choroid. 20133709825
self-resistance in actinomycetes producing inhibitors of rna polymerase. 20133710921
error rates in prenatal cystic fibrosis diagnosis. 20133713828
a new species of the early tertiary rodent thisbemys. 20133716069
destruction of both extensive local recurrent and primary breast cancer with topical aqueous 5-fu: a clinical observation. 20133719590
[multifocal hydatid cysts in children].from 1981 to 1983, 112 children have been operated on for hydatidosis, 26 of them presented multifocal hydatid cysts. in half cases the lung was affected, in association with an abdominal affect. in 6 cases it was a bilateral pulmonary localisation. the check-up is essentially with two exams: thoracal radiology, front and side view; and abdominal echography. the hydatic serology confirms the parasitic origin. 40 surgical operations have been necessary for 21 children carried 171 hydatid cysts. t ...20133719886
composition of major outer membrane proteins of vibrio vulnificus isolates: effect of different growth media and iron deficiency.the outer membrane proteins of vibrio vulnificus including isolates from humans, seawater and an asari clam were examined by sodium dodecyl sulfate (sds)-polyacrylamide gel electrophoresis. a major outer membrane protein with an apparent molecular weight of 48,000 (48k protein) was common to all the strains grown in 3% nacl-nutrient broth; however this 48k protein was not produced in any of the strains grown in chemically defined medium. other major outer membrane proteins with molecular weights ...19863724558
[conservative treatment in splenic injuries. results of a follow-up in patients with autotransplants]. 20133725057
the dorsal approach for internal fixation of fractures of the lateral malleolus.anatomic reduction and internal fixation of the lateral malleolus are the key to management of ankle fractures. the usual application of one-third tubular plates to the lateral surface of the distal fibula has certain disadvantages. in selected cases we prefer a dorsal approach to the lateral malleolus. indications, technique and experience are discussed.20133725110
[intracranial aneurysms and subarachnoid hemorrhage in children and adolescents].42 cases concerning symptomatic intracranial circulation aneurysms and spontaneous sah have been observed by the authors during the period 1965-1984; 37 of them were treated from 1970 on. this group represents 2.6% in the number of patients treated for sah during the above mentioned period in the series of pavia and verona neurosurgery. in 7 cases angiography did not evidence any malformation responsible for the hemorrhage. these cases have been defined as "sine materia" sah. in 33 cases was doc ...20113725140
correlation of double-contrast high-density barium enema, colonoscopy, and histology in children with special attention to disparities.colonoscopic and double-contrast high-density barium enema (dcbe) findings were correlated in 68 patients (39 boys and 29 girls) aged 6 months to 18 years (mean 11.6 years) evaluated over a 24-month period. there was excellent correlation in 53 patients (78.0%) and good correlation in another 3 (4.4%) who had identical diagnoses and only slightly differing extent of disease reported. in 2 of these, dcbe showed more extensive disease, confirmed histologically in 1. distal colitis seen on colonosc ...20133725447
time-resolved x-ray diffraction studies of the b in equilibrium d structural transition in the dna double helix.because of the relation between topology and function, there has been much interest in the structural transitions of the various conformations of dna polymers. the x-ray fiber diffraction analysis system at the daresbury synchrotron radiation source was used to study the reversible transition between the b and d forms of the synthetic dna poly[d(a-t)].poly[d(a-t)]. the gradual progression of conformations between these two forms indicates that the dna double helix does not undergo a change of ha ...20133726529
virulence of vibrio vulnificus strains from marine environments.vibrio vulnificus strains isolated from geographically diverse marine sources were compared with clinical isolates for phenotype and in vitro and in vivo production of virulence factors. there were no differences between environmental and clinical strains on the basis of biochemical characteristics or antimicrobial susceptibility patterns. cytolysin and cytotoxin titers produced by environmental strains were generally comparable to those of clinical strains. of 29 environmental isolates tested, ...19863729387
plasmid carriage in vibrio vulnificus and other lactose-fermenting marine vibrios.a total of 42 clinical and environmental isolates of vibrio vulnificus were examined for plasmid carriage. of these, only five (12%) harbored plasmids, which were of various molecular weights. in contrast, 20 of 32 (62.5%) unidentified lactose-fermenting vibrio spp. were found to possess plasmids with masses of 2.1 to 150 megadaltons. in these isolates, multiple plasmids were common, with an average of 2.25 plasmids per plasmid-containing strain. attempts to demonstrate a correlation with the pl ...19863729404
purification and initial characterization of the 71-kilodalton rat heat-shock protein and its cognate as fatty acid binding proteins.the major rat heat-shock (stress) protein and its cognate were purified to electrophoretic homogeneity from livers of heat-shocked rats. both proteins exhibited similar behavior on a variety of column chromatography matrices but were separable by preparative isoelectric focusing under nondenaturing conditions by virtue of a 0.2 ph unit difference in isoelectric point. both purified proteins had similar physical properties, suggesting the possibility that they may have similar biological function ...19863730359
radiation-induced stenosis of the left main coronary artery.a case of isolated left main coronary artery stenosis ten years following irradiation of the mediastinum for hodgkin's disease is presented. aortic biopsies were consistent with changes suggestive of radiation arteritis.20133731265
measurement of sebum output using a lipid absorbent tape.a sebum absorbent tape is introduced as a reproducible and convenient method for estimation of sebaceous gland output. we have tested the reproducibility of this method by serial measurements of sebum excretion rates (ser) of 10 individuals over a 6-week period, and in addition we have correlated this method with the conventional hexane extraction technique. the sebum absorbent tapes gave consistent values for the sers, and within subjects variation over the 6-week period was statistically nonsi ...20133734473
pha responsiveness and adherent cell-lymphocyte interactions in patients with advanced malignant tumors of the ovary prior to treatment and during chemotherapy.dna synthesis in cultures of pha-stimulated blood mononuclear cells from patients with advanced malignant tumors of the ovary before treatment was significantly reduced and responses of lymphocytes alone were, on an average, 40% lower than in control subjects. adherent cells were found to suppress the pha response of autologous lymphocytes from 6/12 patients before treatment, 4/18 patients during chemotherapy and only in 2/19 control subjects. the net effects of adherent cell-lymphocyte interact ...20133736722
mri: applications in soft tissue anatomy. 20133739418
preparation, isolation and characterization of mouse ige monoclonal antibodies against trichosanthin protein. 19863739501
prognostic indicators in idiopathic iga mesangial nephropathy.univariate survivorship analysis of a cohort of 365 patients with idiopathic iga mesangial nephropathy and at least one year of further observation since the apparent onset (mean = 7.79 +/- 6.19 years; median = 6.16 years) has been performed. observations for at least one year (mean = 5.05 +/- 3.66; median = 4.08 years) after biopsy was available for 292 of these. one immunohistological, four clinical, and six histological features were associated with increased risk of developing renal failure: ...20123749442
prognostic indicators in idiopathic iga mesangial nephropathy.univariate survivorship analysis of a cohort of 365 patients with idiopathic iga mesangial nephropathy and at least one year of further observation since the apparent onset (mean = 7.79 +/- 6.19 years; median = 6.16 years) has been performed. observations for at least one year (mean = 5.05 +/- 3.66; median = 4.08 years) after biopsy was available for 292 of these. one immunohistological, four clinical, and six histological features were associated with increased risk of developing renal failure: ...20123749442
a reappraisal of the complement fixation test using soluble mycobacterium avium antigen for the detection of m. paratuberculosis infection in cattle.serums from 263 cattle suspected of having paratuberculosis on the basis of clinical signs, were tested for antibodies to mycobacterium paratuberculosis with a complement fixation test (cft) employing a heat extracted, soluble m. avium antigen. microscopic examination confirmed that 172 (65.4%) clinically affected animals had paratuberculosis, the remainder being disease-free. the specificity and sensitivity of the cft was 92.3% and 74.4% respectively. phenol treatment of serums before testing w ...19863753338
calmodulin gene expression during sea urchin development: persistence of a prevalent maternal protein.calmodulin gene expression during embryogenesis of the sea urchin strongylocentrotus purpuratus was investigated. several identical bacteriophages containing a cdna insert encoding sea urchin calmodulin (cm-1) were identified by screening a lambda gt10 library of s. purpuratus gastrula-stage cdnas with a chicken calmodulin cdna sequence. a 1.2-kb cdna fragment from cm-1 was subcloned into puc-8 to give plasmid pcal-8. pcal-8 contains a single open reading frame encoding 79 amino acids, a termina ...19863753945
a computer model of neck muscle endurance and fatigue as a function of helmet loading.a series of experiments were conducted in which the neck muscles of volunteer subjects were dynamically and statistically loaded by systematic variations of twenty-four headgear configurations consisting of eight different centers-of-gravity (cgs) times three different weights. six subjects would rotate their heads laterally (from side-to-side) for 30 min with each of the headgear loading combinations. immediately thereafter, the subject would position his head in an isometric head dynamometer a ...20133754195
studies on cardiac distribution and function of neuropeptide y.high concentrations of a novel peptide, neuropeptide y, have been demonstrated in the guinea-pig and canine heart and in the latter, a particularly high concentration was found in the region of the coronary vasculature (126 +/- 31 pmol g-1). intra-arterial infusion of neuropeptide y for 30 s into the coronary artery of the intact, innervated dog heart resulted in a rapid and short-lasting reduction of blood flow from 38 +/- 4 to 31 +/- 3 ml min-1 (p less than 0.05) to resume control level, 39 +/ ...19863754377
reference ranges and ideal patient values for blood cholesterol. can there be reconciliation?reference ranges for blood cholesterol levels reflect the nationwide epidemic of "silent" hypercholesterolemia. as such, reference ranges for cholesterol levels without accompanying designation of levels associated with increased coronary risk are misleading and falsely comforting to physicians and patients. in a recent continent-wide study of 108 academically based clinical laboratories, highly variable reference ranges were observed, the ranges having been derived from a vast assortment of sou ...20133754717
effect of alterations in lipid packing order by hydrophobic solutes on the association state of protein assemblies in model membranes.the effects of two hydrophobic solutes which perturb lipid packing order, permethrin and allethrin, on the aggregated state of a lipid membrane-incorporated protein, bacteriorhodopsin (br), have been determined by resonance energy transfer measurements. as temperature is increased from well below the main gel-fluid phase transition temperature (tc) of the lipid, patches of aggregated br dissociate into monomers, a few degrees below the tc (m.p. heyn, a. blume, m. rehorek and n.a. dencher, bioche ...19863754778
stabilization of intracellular recordings in the cat spinal cord using high-frequency ventilation.stabilization of intracellular recordings by a substantial reduction of respiratory motion may be accomplished by the use of high-frequency ventilation (600-800 breaths/min). the technique is a simple one and enables maintenance of relatively constant blood gas tensions. although the improved stability was demonstrated in experiments performed on alpha motoneurones in the thoracic spinal cord, it is anticipated that a reduced respiratory movement should benefit recordings in other spinal and sup ...19863756629
renal lesions following viper bites--a study of 14 years. 20093759161
disturbances of bone growth in a child who survived septic shock. 20123760793
[acute myocardial infarction during fasting]. 20133765158
aggressive combination therapy in the successful management of life-threatening intracranial hemorrhage in a patient with idiopathic thrombocytopenic purpura.we describe acute therapy for a 13-year-old female from panama with chronic idiopathic thrombocytopenia purpura (itp) refractory to steroids, splenectomy, vinca alkaloids, and azathioprine. she presented with neurologic deterioration from a posterior fossa intracranial hemorrhage (ich). this followed a 3-month history of severe dysfunctional uterine bleeding, progressive from menarche, which had required multiple red cell transfusions. steroid and vinblastine therapy and transfusion of 40 u of p ...20113766911
treatment of localized neuroblastoma.the treatment of neuroblastoma must take into account the prognosis as determined at the time of diagnosis. the stage is an important prognostic factor. in evans's stage i neuroblastoma, surgery is curative in itself and adjuvant treatment is not needed. in evans' stage ii, it is our opinion that the presence of involved lymph nodes worsens the prognosis. therefore, we suggest that patients with stage ii should be divided into stage iia (without lymph node involvement) and stage iib (with lymph ...20113766913
hypopigmented mycosis fungoides. speculations about the mechanism of hypopigmentation.hypopigmented, nonatrophic macules are an unusual manifestation of lesions of early mycosis fungoides. presented herein is a patient with such lesions and an unusual mask-like hypopigmentation of the face. we review both the clinical and microscopic findings in this patient and in previously reported patients with hypopigmented lesions of mycosis fungoides. finally, speculation is made as to the mechanisms of the hypopigmentation.20113766921
breath hydrogen concentration and small intestinal malabsorption in calves.breath hydrogen concentrations were measured to assess intestinal carbohydrate malabsorption in preruminating calves. oral administration of 1.25 g of lactulose (a nonabsorbable carbohydrate)/kg to calves produced breath hydrogen concentrations significantly (p less than 0.001) higher than values determined after calves were fed milk and before the treatment was given. this indicates that, in the calf, fermentation of nonabsorbed carbohydrates results in increased breath hydrogen values. to indu ...19863767107
sensitive analytical method for serum primidone and its active metabolites for single-dose pharmacokinetic analysis in human subjects. 19863769107
visual half-field presentations of incongruent color words: effects of gender and handedness.right-handed (dextral) and left-handed (sinistral) males and females (n = 15) were compared for language lateralization in a visual half-field (vhf) incongruent color-words paradigm. the paradigm consists of repeated brief (less than 200 msec) presentations of color-words written in an incongruent color. presentations are either to the right or to the left of center fixation. the task of the subject is to report the color the word is written in on each trial, ignoring the color-word. color-bars ...20133769495
effects of sustained intravenous diltiazem infusion in healthy persons.a 3-stage infusion of diltiazem was tested in 8 subjects for up to 48 hours: a bolus injection (10 mg over 3 minutes), a rapid loading infusion (20 mg over 30 minutes) and a maintenance infusion (10 mg/hour to the end of the study). this regimen produced stable median plasma diltiazem concentrations of approximately 150 ng/ml. the median half-life of elimination for diltiazem was 206 minutes (range 144 to 452) and median total clearance was 980 ml/min (range 665 to 1,907). the pr interval length ...20133776858
wheelchair use by ambulatory nursing home residents.in a survey of wheelchair use in two nursing homes, the authors found a substantial number of cognitively intact nursing home residents who walked, but who also used a wheelchair. using chart review and interviews with the residents, it was found that multiple physical factors, including pain, strength, endurance, vision and balance, and multiple social and environmental factors, including the fear of falling, were related to the resident's decision to use a wheelchair as an alternative means of ...20133782699
diagnosis formulation by residents and physicians at different levels of experience. 20133783644
[the anti-insulin receptor antibody syndrome]. 20113785115
[new aspects of vitamin k prophylaxis in newborn infants and infants].discussion about vitamin k prophylaxis has again become a matter of major concern since cases of life threatening bleeding due to late onset vitamin k deficiency have been observed in germany. this review tries to summarize present knowledge about the clinical presentation, pathogenesis and the potential prevention of vitamin k deficiency caused bleeding in the neonatal period and infancy.20113785234
haemothorax in the course of chickenpox. 20133787528
[unusual cause for the development of hemoperitoneum].the authors describe an unusual origin of haemoperitoneum in a young woman. the hemoperitoneum appeared twice in a period of 10 months. the first attack was mild and atypic. in both cases the hemoperitoneum was preceded by a sexual intercourse, during which the ovary resp. the ovarian cyst were injured. the authors suggest that the coital rupture of the ovary is a very common cause of these states. the diagnosis of inapparent bleeding in the abdominal cavity is always very difficult and without ...20133788343
participation of iron on the growth inhibition of pathogenic strains of mycobacterium avium and m. paratuberculosis in serum.serum, which is low in freely-available iron, was bacteriostatic for m. avium and m. paratuberculosis irrespective of the ability of these organisms to produce the iron-chelators mycobactin and exochelin for iron acquisition. bacteriostasis was overcome when the serum was supplemented with exochelin or mycobactin, but only if the mycobacteria had previously adapted to growth in a low iron environment. the results imply that for studies on mycobacterial pathogenicity the test cultures should be g ...19863788345
isolation and characterization of a mucin-degrading strain of peptostreptococcus from rat intestinal tract.a mucin-degrading microorganism was isolated from the intestinal tract by serial sectioning from the serosal side of the caecum wall from a conventional rat. the ability of degrading the intestinal water-soluble mucin was present both in vivo after monocontamination of germ-free rats and in vitro, when adding the microbe to mucin medium. the morphology, gram-positive cocci single or in short chains and the very weak biochemical activities allow us to place this strain in the species peptostrepto ...19863788570
bioluminescence in a strain of the human pathogenic bacterium vibrio vulnificus.we report the existence of a bioluminescent strain of the human pathogen vibrio vulnificus. the isolate was obtained from blood following a fatal wound infection and thus represents the first description of an infection caused by a luminescent bacterium.19863789716
rapid serological identification of vibrio vulnificus by anti-h coagglutination.staphylococcus aureus cowan 1 cells were armed with anti-flagellar (anti-h) antibody produced in rabbits immunized with flagellar core protein prepared from vibrio vulnificus. this reagent was assessed by coagglutination for its capacity to agglutinate and identify v. vulnificus. a species-specific h antigen is expressed in the core proteins of the polar flagella of v. vulnificus. of 435 v. vulnificus isolates identified bacteriologically, 432 (99.3%) were agglutinated in the slide test within 2 ...19863789720
comparison of histones in normal and xeroderma pigmentosum lymphoblastoid cells.histones from normal human and xeroderma pigmentosum, complementation group a (xpa), lymphoblastoid cells were compared both quantitatively, qualitatively and for binding affinity for dna. electrophoretic examination of the histones showed that all five major histone species were present in both cell groups and that there were no quantitative differences between normal and xpa histones. binding affinity to [3h] mammalian dna of the histones was determined. no significant differences were observe ...19863791423
incidence, clinical significance and prognosis of ventricular fibrillation in the early phase of myocardial infarction.of 1265 patients admitted to the ccu with the diagnosis of acute mi, 96 (7.6%) developed ventricular fibrillation within 72 hours following admission. of these 96, 35 (36.5%) had secondary vf associated with left ventricular failure; they had a high in-hospital mortality of 57.1%. the remaining 61 (63.5%) had primary vf, i.e. vf occurring in the absence of significant lv failure. fourteen of these (23%) died in hospital: 9 due to pvf (3 during the first episode, 6 during a recurrence). this mort ...20133792355
local anaesthetics. iv--synthesis and activity of 2-(n-substituted or n,n-disubstituted aminoacetamido)-4- or -4,5-substituted thiazoles.synthesis is described of eleven new 2-(n-substituted or n,n-disubstituted aminoacetamido)-4- or -4,5-substituted thiazoles (i). their hydrochlorides were screened for local anaesthetic activity on frogs by the sciatic plexus method and the activity compared with that of procaine.20133792539
surgical management of peritoneal dialysis catheters in children: five-year experience with 1,800 patient-month follow-up.currently at our institution more than 90% of the children with end-stage renal disease are managed with continuous ambulatory peritoneal dialysis (capd) in preference to hemodialysis until a successful transplant is accomplished. recent refinements in capd catheters and dialysis techniques have greatly added to the many medical, psychological, and economic advantages of capd compared with chronic hemodialysis. ninety-three patients less than 21 years of age underwent insertion of 167 peritoneal ...19863794985
bilateral renal metastases from squamous cell carcinoma of the anus.we report a case of bilateral renal metastases from squamous cell carcinoma of the anus. the patient underwent sequential bilateral radical nephrectomy, and has remained free of disease and in good health on dialysis for more than 8 months.20133795375
[a case of vibrio vulnificus infection]. 19863795561
[rates of incidence and prevalence of various neuromuscular diseases in the udine and pordenone provinces]. 20133796514
[changes in the characteristics of glucocorticoid hormone binding in human peripheral blood lymphocytes during myocardial infarct].competitive binding was used to determine the number of binding sites to glucocorticoid hormones in peripheral blood leukocytes of normal subjects, patients with unstable angina pectoris and patients with myocardial infarction. a sharp (2-3-fold) increase in the number of binding sites was observed in patients with myocardial infarction during the first 24 hours after the onset of the disease.19863801148
effect of age, sex, and body surface area on echocardiographic left ventricular wall mass in normal subjects.m-mode echocardiography was used to estimate left ventricular wall mass in 136 older normal subjects (group i: 78 men and 58 women, ages 20 to 97 years) and 105 younger normal subjects (group ii: 52 male and 53 female subjects, ages 1 day to 23 years). echocardiographic left ventricular mass (in grams) was estimated from the following formula: left ventricular mass = 1.05 ([ left ventricular internal diastolic dimension + ventricular septal thickness (diastole) + posterior wall thickness (diasto ...20133804398
mouse skin damage caused by cytolysin from vibrio vulnificus and by v. vulnificus infection.light and electron microscopy of mouse skin damage caused by intradermal infection with a virulent strain of vibrio vulnificus and by a single intradermal injection of the cytolytic toxin produced by the bacterium revealed similar structural alterations. the epidermis was intact; however, the infection and toxin produced acute cellulitis characterized by extensive extracellular edema; disorganization of collagen bundles; large accumulations of cell debris and plasma proteins; damaged or necrotic ...19873805762
the role of the paediatric endoscopist.the role of the paediatric endoscopist has been a changing one. when i first commenced at the royal alexandra hospital for children in sydney 25 years ago, paediatric endoscopy of the upper respiratory tract and oesophagus was a limited and poorly defined field. most endoscopic examinations were requested, often reluctantly, by a paediatrician in the investigation of stridor. in fact my first consultation involved instructions to perform a laryngoscopy, but not a bronchoscopy and general anaesth ...20133805880
associated postural adjustments in parkinson's disease.postural activity in muscles of the back and legs associated with voluntary forward elevation of the arm at the shoulder with the subject standing was examined in 14 patients with parkinson's disease and nine normal individuals. the time of onset of emg activity in each of the postural muscles, relative to the onset of activity in the prime mover, was the same for both patient and normal groups and did not depend on load. the amplitude of the emg bursts and their frequency of occurrence, was les ...20133806114
pneumonia--the quality of medical records data.the quality of medical records data for patients who were hospitalized with community-acquired pneumonia was assessed by comparing medical records data with data obtained in a prospective study of pneumonia for the period april 1, 1984, to december 31, 1984. one hundred five patients fulfilled the case definition of pneumonia for entry into the prospective study. one hundred twenty-seven patients were identified by medical records data. seventy-three of the patients appeared in both studies. the ...19873807447
[analysis of hba1 is necessary in the routine check-up of patients with type 2 diabetes mellitus]. 20133807486
[improved treatment of obstructive apnea syndrome with palatopharyngoplasty]. 20133807487
[development of esophageal cancers in patients following cardiomyotomy].during a 20 year period we observed that in six patients with carcinoma of the esophagus associated with achalasia, four patients had had a prior heller operation. fifty patients with achalasia of the esophagus took part in endoscopic and histologic surveillance 5-15 years after cardiomyotomy. we have found a correlation between the severity of histologic changes and the duration of symptoms before the operation. it seems reasonable to advise early therapy to avoid the development of a dilated, ...20133807499
[role of foci of chronic infection of orl organs in the pathogenesis of neurodermatitis]. 20133811584
[aerobic capacity estimated from heart rate under submaximal load: an indicator of complaints, personality, personal activity and social status].in 34 young females (mean: 21 years, range 18-30), working with vdts, maximum aerobic capacity (mac) was estimated by use of a cycle ergometer and astrand's nomogram. mac correlated with musculoskeletal complaints (-.29, p less than .05), eye complaints (-.36, p less than .05), personal activity (.38, p less than .05), personality dimensions: "imperturbability" (.41, p less than .01), "wellbeing" (.31, p less than .05), "traditionalism" (-.45, p less than .01) and "psychophysic constitution" (al ...20133811609
[surgical wound infection after spondylodesis with instrumentation]. 20133811754
comparison of the pharmacological properties of pituitary and biosynthetic human growth hormone. demonstration of antinatriuretic/antidiuretic and barbital sleep effects of human growth hormone in rats.biosynthetic human growth hormone was compared with pituitary human growth hormone and pituitary 22 k in the weight gain and the tibia test. the three preparations were found to be equipotent. furthermore, the growth hormones were compared in various pharmacological test systems. all three preparations were found to have a marked antidiuretic and antinatriuretic effect in the rat and to cause a significant shortening of the hexobarbital sleeping time in mice. biosynthetic and pituitary preparati ...19873811769
the role of androstenedione and testosterone in the reproduction and antler growth of a male white-tailed deer.seasonal levels of androstenedione and testosterone were investigated in plasma of mature intact and castrated male white-tailed deer. in four intact bucks, androstenedione concentrations were low in february and march (around 1 nmol/l) and then increased significantly (p less than 0.05) from april to november (peak 2.34 nmol/l). testosterone remained low (below 3.5 nmol/l) from february to august and then rose significantly (p less than 0.01) till november (peak 36.78 nmol/l). both hormones dec ...20133811770
individual differences in the signed communication of deaf children. 20133812164
the incidence and significance of seminal vesicle invasion in patients with adenocarcinoma of the prostate.the incidence and significance of seminal vesicle invasion in patients with adenocarcinoma of the prostate were determined in 139 patients who underwent radical prostatectomy. of the 36 patients who had seminal vesicle invasion, 27 (75%) also had capsular invasion and 13 (43%) had lymph node metastases. disease progression rates were 31% and 58% at 5 and 8 years, respectively. survival rate at 5 years was 90.6% and at 8 years it was 83.7%. of the 103 patients without seminal vesicle invasion, 21 ...20093815316
[diet in the prevention of coronary disease]. 20083815423
[diet in the prevention of coronary disease]. 20083815423
the cell-to-cell channel of gap junctions. 20133815521
evaluation of the hereditary syrian hamster cardiomyopathy by 31p nuclear magnetic resonance spectroscopy: improvement after acute verapamil therapy.the relation between metabolic and functional derangement in various cardiomyopathies has not been well characterized. this information was specifically sought in a spontaneous cardiomyopathic model. metabolic and hemodynamic parameters were obtained in glucose-perfused beating hearts of 180-200-day-old cardiomyopathic syrian hamsters and age-matched healthy animals. this period in the cardiomyopathic hamster lifetime is intermediary between the necrotic phase and the appearance of heart failure ...19863815756
cervical lymph node metastases with occult primary.patients with cervical metastases from an unknown primary tumour present both diagnostic and therapeutic problems. twenty patients with a metastatic lesion in the neck, in whom the primary tumour was not found despite extensive, diagnostic procedures, were treated in the department of otolaryngology, linköping university hospital, during a 14-year period (1971-1984). since 1975 tonsillectomy has been performed regularly on the affected side as a part of the diagnostic procedure. eight patients w ...20123815873
clinical and ecological characteristics of vibrio vulnificus in the northeastern united states.multiple seawater sites in the northeastern united states, particularly long island sound, and shellfish from long island sound were sampled from april to november for 3 successive yr, 1983-1985. hospitals in coastal and metropolitan areas of connecticut were surveyed for the same 3-yr period, vibrio vulnificus can be found in these waters during the summer months. the appearance of these virulent bacteria in both seawater and shellfish are a function of the water temperature; no v. vulnificus c ...19873816129
vibrio vulnificus infection after raw oyster ingestion in a patient with liver disease and acquired immune deficiency syndrome-related complex.sepsis, peritonitis, and gastroenteritis developed in a 45-yr-old homosexual man 1 day after ingestion of raw oysters. the patient had chronic active hepatitis and cirrhosis with hepatitis b virus and delta-infection. he also had persistent generalized lymphadenopathy associated with htlv-iii antibody positivity. vibrio vulnificus was isolated from the patient's blood and peritoneal fluid as well as from the same batch of oysters at the restaurant where the patient had visited. to our knowledge, ...19873817400
processing-independent in vitro translocation of cytochrome p-450(scc) precursor across mitochondrial membranes.in the presence of a membrane-permeable metal chelator, bovine adrenal cortex mitochondria imported p-450(scc) precursor without processing of the amino-terminal extension peptide. the imported precursor was bound to the matrix side surface of the inner membrane. when the inhibition due to the metal chelator was removed, the imported precursor was processed to the mature form. unprocessed precursor was also detected in mitochondria when the import reaction was carried out at relatively low tempe ...19863818579
chemical reduction system for the detection of phylloquinone (vitamin k1) and menaquinones (vitamin k2).both isocratic and gradient elution systems for fluorometric detection of k vitamins after post-column reduction with zinc metal to their hydroquinones are described. the reaction detection system for k vitamins (phylloquinone and menaquinones) in liquid chromatography is based on reduction of k vitamins to their corresponding hydroquinones with zinc metal in the presence of zinc ions. it was found that 95% of the injected quinones (k vitamins) could be reduced to their corresponding hydroquinon ...20113818857
[pacemaker implantation in infants and children for atrioventricular block]. 20143819491
similarity principles and intrinsic geometries: contrasting approaches to interspecies scaling.we criticize standard allometric approaches on the grounds that they emphasize scaling to one variable at a time, whereas chemically reactive hydrodynamic systems involved in pharmacokinetic phenomena are of higher dimension. we show that attempts based on mechanical similitude to set a dosage that would be equivalent across species (for example, from mouse to humans) lead to ambiguous results. another failing of standard allometry may be its incapability to accommodate the neoteny of homo sapie ...19863820095
isolation and properties of a novel igg-binding protein from streptococci of serological group u.a nonimmune binding of immunoglobulin (ig) g has been detected in streptococci of group u. the group u fc-binding site differed from the five previously known types of staphylococcal and streptococcal fc-binding sites by its strong affinity for murine igg, with dissociation constants in nanomolar range for rat and mouse igg, as well as for mouse igg subclasses 1, 2a, 2b and 3. it also differed from other binding sites by the high sensitivity towards trypsin. the fc-binding protein could be solub ...19873821654
[primary localization of a malignant lymphoma in the salivary gland--case report]. 20133821669
reaction to injectable collagen: results in animal models and clinical use.since its commercial release, zyderm collagen implant has been used to treat more than 200,000 subjects in the united states for soft-tissue contour defects and more than 250,000 patients internationally (including the united states). approximately 3 percent of subjects' skin tested with zyderm collagen experience localized hypersensitivity reactions to collagen, whereas approximately 1 percent of treated patients demonstrate symptoms of hypersensitivity at treatment sites. of the latter treatme ...19873823250
identification of environmental vibrio vulnificus isolates with a dna probe for the cytotoxin-hemolysin gene.we screened 44 lactose-positive vibrio strains isolated from the marine environment for homology with a 3.2-kilobase dna fragment encoding the vibrio vulnificus cytotoxin-hemolysin gene. all 29 marine isolates identified as v. vulnificus on the basis of numerical taxonomy and dna-dna hybridization studies hybridized with the cytotoxin gene probe, as did all v. vulnificus reference strains. homologous gene sequences were identified in no other lactose-positive marine vibrio isolates nor in 10 oth ...19873827248
cimetidine versus ranitidine: single-dose, oral regimen for reducing gastric acidity and volume in ambulatory surgery patients.this placebo-controlled trial compared the efficacy of single oral doses of cimetidine or ranitidine in maintaining intragastric ph and volume greater than 2.5 and less than 25 ml, respectively, in ambulatory surgery patients requiring general anesthesia. patients were randomized to receive either placebo, ranitidine hcl 150 mg, or cimetidine hcl 400 mg upon rising on the morning of surgery. at induction, the cimetidine and ranitidine groups had significantly higher (p less than 0.05) gastric ph ...20133829912
[an experimental study on adhesion blocking in simultaneous injury of tendon and nerve].the formation of adhesions between simultaneously injured tendon and nerve with and without adhesion blocking materials was studied by using a rabbit model. a collagen membrane, produced from adult bovine corium and with a negative electric charge induced by chemical modification, was used as the blocking material. microangiography and histological studies were performed to investigate the vascular supply to the adhesions. the following results were obtained. blood vessel proliferation was obser ...19853831164
confidentiality and the medical report. 20133831650
[effect of titanium phosphate, zirconium oxide and a mixture of ammonium phosphotungstenate with zirconium phosphate on the elimination of radioactive cesium from the bodies of rats]. 19853835674
the liver and metabolic bone disease. 20133837818
degenerative lesions of a coronary chemoreceptor and nearby neural elements in the hearts of victims of sudden death.a coronary chemoreceptor and its neighboring nerves and ganglia were studied by serial sections of tissue taken from the hearts of sixteen victims of sudden unexpected death. either focal or extensive inflammatory destruction was present in the chemoreceptors of 13 of the 16 hearts, and similar abnormalities of local nerves and ganglia were present in all 16 hearts. since an identical coronary chemoreceptor in the dog has previously been shown to be the site of origin of a powerful reflex with m ...19863837961
isolation and characterization of neuropeptide y from porcine intestine.the isolation and primary structure of intestinal neuropeptide y (npy) is described. the peptide was purified from porcine intestinal extracts using a chemical assay and radioimmunoassay for npy. the amino acid sequence of this peptide is: tyr-pro-ser-lys-pro-asp-asn-pro-gly-glu-asp-ala-pro-ala-glu-asp-leu-ala- arg-tyr-tyr- ser-ala-leu-arg-his-tyr-ile-asn-leu-ile-thr-arg-gln-arg-tyr-nh2. this the structure of intestinal npy is identical to the npy of brain origin.19853838090
emotions and obesity among mexican-american children.the purpose of this study was to determine what relationships, if any, existed between high levels of body fat and emotional motivations for eating among mexican-american children. subjects (n = 177) were drawn from children aged 10-14 years who participated in the national youth sports program in the lower rio grande valley region of texas. data were gathered through a self-report instrument dealing with emotional motivators involved in eating and through individual anthropometric measurements. ...20133845258
preventing complications for the toxic shock syndrome patient. 20133848384
chemoattractants in fibrotic disorders.fibrosis represents an excessive deposition of connective tissue which impedes the normal functions of an organ or tissue. the mechanisms leading to this increased deposition of connective tissue may be similar to those occurring in normal wound repair. we have previously shown that the repair process involves the migration of connective tissue cells to the site of injury and their subsequent proliferation. one of the principal factors controlling these events appears to be the platelet-derived ...19853851719
human c-myc and n-ras expression during induction of hl-60 cellular differentiation.the genome of the human hl-60 promyelocytic leukemia cell contains amplified c-myc sequences and the transforming n-ras oncogene. the present study has monitored c-myc and n-ras expression in hl-60 cells during induction of myeloid and monocytic differentiation with dimethyl sulfoxide, hexamethylene bisacetamide, 12-o-tetradecanoylphorbol-13-acetate and 1,25 dihydroxy-vitamin d3. the results demonstrate that induction of hl-60 differentiation is associated with decreases in c-myc rna, while ther ...19853856429
selective uptake of a toxic lipophilic anthracycline derivative by the low-density lipoprotein receptor pathway in cultured fibroblasts.n-(n-retinoyl)-l-leucyldoxorubicin 14-linoleate (r11-dox), a new lipophilic derivative of doxorubicin, was synthesized and incorporated into low-density lipoprotein (ldl). the drug-ldl complex contained 100-200 drug molecules/ldl particle. when cultured normal human fibroblasts were incubated with 125i-ldl-incorporated drug, there was a perfect correlation between the cellular uptake plus degradation of 125i-ldl and the cellular drug accumulation. the presence of excess native ldl inhibited the ...19853856679
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