Publications

lost sampling units and investigational power.		2005	1456081
structure of the proteolytic fragment f34 of calmodulin in the absence and presence of mastoparan as revealed by solution x-ray scattering.	the solution x-ray scattering technique has been applied to examine the conformations of the proteolytic fragment f34 (78asp-148lys) of calmodulin in the absence of both ca2+ and mastoparan, in the presence of ca2+ only, and in the presence of both ca2+ and mastoparan. the radius of gyration and the molecular weight for the f34 fragment increased by 1.1 +/- 0.3 a and 19%, respectively, upon binding of both 2 mol of ca2+/mol to the f34 fragment and mastoparan to form the tertiary complex. a small ...	1992	1457423
sister chromatid exchange (sce) frequency in lymphocytes of patients with colorectal carcinoma treated with razoxane.	the increased risk of neoplasia following cytotoxic therapy for both malignant and nonmalignant disease is well known. sister chromatid exchange (sce) frequencies in patients receiving such chemotherapy are often elevated, and the persistence of high levels after treatment may provide an indicator for susceptibility to secondary neoplasia. the cytostatic drug razoxane has been used for the treatment of psoriasis, acute myeloid leukemia (aml), and colorectal carcinoma. prolonged use of this drug, ...	2006	1458513
cardiac catheterization laboratory survey: 1990. society for cardiac angiography and interventions, laboratory performance standards committee.	a survey of 117 member cardiac catheterization laboratories was undertaken by the society for cardiac angiography and interventions. the survey included numbers and types of procedures, both diagnostic and interventional, in adult as well as pediatric age groups. radiation safety, various laboratory policies, frequency of short stay, and outpatient procedures were tabulated. report generation, training programs, administrative organization, and laboratory equipment were all included. the results ...	2006	1458520
congenital sensory neuropathy with anhidrosis.		2006	1459704
analysis of two human monoclonal antibodies against melanoma.	b cells derived from peripheral-blood lymphocytes (pbl) and tumor-infiltrating lymphocytes (til) from a patient with a high serum antibody titer to autologous melanoma were transformed with epstein-barr virus (ebv) and evaluated for reactivity against autologous tumor. b cells producing antibody reactive with autologous tumor and unreactive with normal fibroblasts were detected both in til and in pbl. one cell line derived from pbl and another derived from til sustained production of tumor-react ...	1992	1459738
identification of surface-exposed yersinia pestis proteins by radio-iodination and biotinylation.	when whole cells (stationary phase) of yersinia pestis strain ev76 were radiolabelled with iodogen and 131i, 16 major and 10 minor surface-exposed outer membrane proteins (omps) were identified. labelling with n-hydroxysuccinimidyl 6-biotinylamino-hexanoate (biotin x-nhs) resulted in a complex protein profile detectable after blotting and developing with peroxidase-conjugated avidin. y. pestis cell fractionation revealed that biotin x-nhs labelled not only omps but also proteins of inner cell co ...	1992	1460662
[accidental falls among the elderly--can anything be done for this problem?].		2002	1462380
eating behavior in continuous ambulatory peritoneal dialysis and hemodialysis patients.	three groups consisting of 12 subjects each (continuous ambulatory peritoneal dialysis [capd] patients, hemodialysis patients, and healthy controls) matched for age, sex, and body weight were invited to a test meal for the study of hunger, fullness, and food preferences. they were served an excess portion of hash served on a plate placed on a hidden scale ("viktor"), which was connected to a computer registering the eating process on-line. the patients filled in visual analogue scales (vas) conc ...	2006	1462988
three novel mutations in the liver-type arginase gene in three unrelated japanese patients with argininemia.	argininemia is caused by a hereditary deficiency of liver-type arginase (e.c.3.5.3.1) and is characterized by psychomotor retardation and spastic tetraplegia. we examined findings in three japanese patients with argininemia, by using the pcr, cloning, and sequencing procedures. we found three different mutations--g-to-a-365 in exon 4, g-to-c-703 in exon 7, and c-del-842 in exon 8--thereby leading to mutant arginase proteins of w122x, g235r, and l282fs, respectively. patient 1 was a compound hete ...	1992	1463019
[injuries of the tarsometatarsal (lisfranc) joint].		2006	1464394
comparative effects of thyroxine and/or retinoic acid treatment in vivo on growth hormone synthesis and release by pituitaries from thyroidectomized rats.	thyroid hormones and retinoic acid (ra) coregulate growth hormone (gh) synthesis and release from cultured pituitary tumor cells by interacting with nuclear receptors that activate gh gene transcription. whether these two compounds share overlapping gh regulatory activities in vivo is unclear. therefore we compared the effects of in vivo replacement therapy with thyroxine (t4) and/or retinoic acid (ra) on gh synthesis and release in pituitaries from hypothyroid rats. three weeks after thyroidect ...	1992	1464411
arthroscopic treatment of flexion deformity after acl reconstruction.	after anterior cruciate ligament (acl) reconstruction, one frequent complication is the restriction of the range of motion and loss of extension. in addition to the presence of adhesions in the suprapatellar pouch, it is possible to detect two different pathological findings in the intercondylar notch: a misplacement of graft causing an intercondylar impingement, or the presence of hypertrophic tissue originating from the graft that blocks the last degrees of extension, causing an "anterior impi ...	2004	1466714
scanning electron microscopy of bacterial biofilms on indwelling bladder catheters.	fifty foley bladder catheters that had been indwelling for periods ranging from 3 to 83 days (mean 35 days) were examined for the presence of bacterial biofilm. scanning electron microscopy on freeze-dried cross-sections and fixed, critical point-dried longitudinal sections revealed biofilm formation on the luminal surfaces of 44 of the catheters. culture of urine samples and sonicates from catheters revealed that the prevalence of bacteriuria was less than that of catheter colonization. a wide ...	1992	1468417
re: endoscopic injection of glutaraldehyde cross-linked bovine dermal collagen for correction of vesicoureteral reflux.		1992	1472245
estimates of hiv infection among injecting drug users in glasgow, 1985-1990.	to use research and surveillance studies in glasgow (scotland, uk) to estimate the number of current injectors infected with hiv, the total number of injectors infected up to the end of 1990 and the recent incidence of infection.	1992	1472341
plague surveillance by serological testing of coyotes (canis latrans) in los angeles county, california.	sera from 19 (5.6%) of 338 coyotes (canis latrans) collected in los angeles county, california between 1986 and 1990 had antibodies against yersinia pestis using the passive hemagglutination test. coyotes were excellent sentinels of plague activity in los angeles county. enzootic plague declined dramatically in the county during the 5-yr period.	1992	1474660
evidence of coexisting spondyloarthropathy and sickle-cell disease.		2006	1475643
[use of conventional and complementary medical care in patients with chronic non-cancerous pain].	the use of medical care was surveyed among 157 chronic pain patients. half of them had consulted more than 6 and up to 17 specialists in "conventional" medicine for their pain problem. moreover, 46% had used "complementary" medicine. they had tried many different "alternative" therapies in 40% of the cases. the users of "complementary" medicine, mostly females, also sought care from a significantly higher number of "conventional" therapists, had more physiotherapy, took drugs more frequently and ...	2006	1475658
[a case of systemic lupus erythematosus complicated with cerebral infarction].		2006	1479231
[a case of sle occurring after pacemaker implantation].		2006	1479232
is early vascularization of nerve grafts necessary?	revascularization and regeneration through vascularized and non-vascularized nerve grafts were compared on optimal and adverse graft beds in 76 rabbit sciatic nerves. a delay in revascularization of more than 14 days was found to occur in 30 mm long, non-vascularized nerve grafts placed on completely avascular graft graft beds. however, over a period of 44 weeks, this prolonged ischaemia did not adversely affect nerve regeneration. the vascularized nerve grafts did not differ significantly with ...	1992	1479247
factors affecting the strength of flexor tendon repair.	the effects of different thicknesses and configurations of core sutures were studied in human cadaveric flexor tendon repairs. both straight and cyclic load tests were employed. to exploit the full strength of 4/0 suture material, the kessler repair using four locked single knots would seem to be appropriate.	1992	1479249
cochlear implants for congenital deformities.	there have been few accounts of multi-channel cochlear implants in patients with congenital structural deformities of the inner ear which are associated with severe and sometimes progressive deafness. these malformations can now be recognized easily on 2 plane thin section high resolution ct studies which are mandatory for the pre-implantation assessment. however, no attempt seems to have been made to describe which of these malformations would be suitable for an implant or for which would this ...	2006	1479272
sphingomyelinase treatment of low density lipoprotein and cultured cells results in enhanced processing of ldl which can be modulated by sphingomyelin.	the addition of neutral sphingomyelinase from s. aureus to the medium of rat intestinal epithelial cell cultures (iec-6) containing added human low density lipoprotein (ldl) resulted in two- to fivefold increases in ldl uptake and degradation. this overall effect was shown to be the combined result of sphingomyelinase activity on the composition of the ldl particle and a separate action directly on the cells when native ldl was incubated with sphingomyelinase from s. aureus followed by removal o ...	1992	1479284
characterization of an anaerobic fungus from llama faeces.	an anaerobic fungus was isolated from llama faeces. based on its morphological characteristics, polyflagellated zoospores, extensive rhizoid system and the formation of monocentric colonies, the fungus is assigned to the genus neocallimastix. neocallimastix sp. l2 is able to grow on several poly-, oligo- and monosaccharides. it differs from other neocallimastix isolates in its inability to ferment inulin. neocallimastix sp. l2 requires co2 for growth. in the presence of 100% co2 in the gas phase ...	1992	1479350
[associations of the soil amoeba hartmannella rhysodes with the bacterial causative agents of plague and pseudotuberculosis in an experiment].	some aspects of relationships between soil ameba and the causative agents of plague and pseudotuberculosis, capable of forming natural associations, are considered. ameba can phagocytose bacteria causing plague and pseudotuberculosis. cases of the preservation of individual bacterial cells at the stationary phase and in precysts of amebae have been registered.	1992	1481595
[the phages of halophilic vibrios and their use].	the range of the lytic activity of 46 phages of parahemolytic vibrios isolated from lysogenic strains, sea water samples, crabs and mussels has been studied. the phages are represented by virions belonging to morphological groups ii, iv, v according to the phage classification currently used in russia and to different serological groups. no relationship between the sensitivity of vibrio strains to the phages under study and the specificity of serotypes o and k has been established. the preparati ...	1992	1481605
fine structure of the herbst corpuscles in the lingual mucosa of the finch, lonchura striata.	the ultrastructure of herbst corpuscles in the lingual mucosa of the finch, lonchura striata var. domestica, was examined by light and electron microscopy. numerous herbst corpuscles were found at the top of connective tissue papillae just beneath the dorsal epithelium. the herbst corpuscle was composed of an outer capsule, inner core and central axon. the central axon was discoid in shape and immunoreactive for nse-antiserum. the central axon was surrounded by compactly stacked layers of thin l ...	2006	1482599
an evaluation of the effect of the anesthetic agent profofol (diprivan) on the outcome of human in vitro fertilization.		1992	1482846
16th annual symposium on computer applications in medical care. proceedings. baltimore, maryland, november 8-11, 1992.		2006	1482848
a temporal-abstraction system for patient monitoring.	resume is a system that performs temporal abstraction of time-stamped data. resume is based on a model of three temporal-abstraction mechanisms: point temporal abstraction (a mechanism for abstracting values of several parameters into a value of another parameter); temporal inference (a mechanism for inferring sound logical conclusions over a single interval or two meeting intervals); and temporal interpolation (a mechanism for bridging nonmeeting temporal intervals). making explicit the knowled ...	2006	1482852
a framework for the knowledge-based interpretation of laboratory data in intensive care units using deductive database technology.	in co-operation with the institute of anaesthesiology of the ludwig-maximilians-university in munich a computer-based system for the analysis and interpretation of renal function, fluid and electrolyte metabolism of critical care patients has been developed. this paper focuses on the requirements and implementation aspects of the knowledge-based interpretation for this particular system. objective of the proposed approach is, to transform an enormous--and constantly increasing--amount of raw dat ...	2006	1482854
increases in knowledge and use of information technology by entering medical students at mcmaster university in successive annual surveys.	to determine self-reported microcomputer and information technology competency, access, and usage by entering medical students and their perceptions of the need for training in additional applications.	2006	1482936
drug delivery optimization through bayesian networks.	this paper describes how bayesian networks can be used in combination with compartmental models to plan recombinant human erythropoietin (r-huepo) delivery in the treatment of anemia of chronic uremic patients. past measurements of hematocrit or hemoglobin concentration in a patient during the therapy can be exploited to adjust the parameters of a compartmental model of the erythropoiesis. this adaptive process allows more accurate patient-specific predictions, and hence a more rational dosage p ...	1992	1482938
a critical appraisal of the literature on the effects of computer-based clinical decision support systems on clinician performance and patient outcomes.	to review the evaluations of computer-based clinical decision support systems (cdss's).	2006	1482947
the ophthalmic retrobulbar injection simulator (oris): an application of virtual reality to medical education.		2006	1482962
a protocol system to satisfy research specific, disease specific, physician specific, and patient specific informational needs.	the department of medicine at loyola university medical center chicago (lumc) has developed and is utilizing a patient information protocol system (pips) to address clinical and research informational needs. pips, an integrated module of the department's patient information management system (pims), enables end-users to access pre-defined informational templates or "protocols". protocols detail pre-defined data requirements for patient management or clinical research needs. each protocol consist ...	2006	1482966
the process and outcome of a collaborative effort to design and implement a clinician order processing system.		2006	1482980
direct physician entry of injury information and automated coding via a graphical user interface.	injury data in the paper medical record are often inaccurate or lack adequate specificity to evaluate trauma patient care. to improve the quality of recorded injury data, we are testing a graphical, anatomic-based interface for quick collection of detailed injury information directly from the trauma physician. navigation and data collection throughout the interface are facilitated by anatomic illustrations, menus, lists, and "dialog boxes". using a "point and click" method, the user selects a sp ...	2006	1482981
professional doc (pdoc): a software environment for authoring and consulting of electronic documentation. interactive diagnosis and therapy: a medical application.	professional doc (pdoc) is a software environment for electronic documentation authoring and consulting based on the hypermedia technology. it allows to manage different kinds of information (pictures, sounds, texts, graphics, video) organized according to hyperstructures. the user-friendliness and effectiveness of its man-machine interface, and its availability on the most common hardware platforms makes it a suitable product for a very broad category of users. interactive diagnosis and therapy ...	1992	1483002
allocation of attention, reading skills, and deafness.	brannan and williams (1987) found that poor readers cannot successfully utilize parafoveal cues to identify letter targets. whether a similar deficit in the use of cue information occurs in deaf poor readers and whether it is only specific to processes that capture attention automatically were investigated in congenitally deaf young adults classified as poor or good readers and hearing controls classified as good readers. subjects were presented with central or parafoveal cues that varied in cue ...	2006	1483191
watching a generation die: canadian doctors and the battlefields of world war i.		2006	1483240
twinning and the r/k reproductive strategy: a critique of rushton's theory.	the theory of r selection, favoring population growth, as opposed to k selection, favoring more efficient utilization of resources, has in recent years been applied by rushton to contrast human ethnic groups in terms of their r/k reproductive strategies, suggesting the existence of a continuum from r groups, producing many offspring but providing little parental care, to k groups, producing few offspring but providing much parental care. rushton's theory, which is largely based on ethnic differe ...	1992	1488860
radiotherapy of malignant melanoma of the uvea with i-125 seeds.	nineteen patients with malignant uveal melanomas were treated with i-125 applicators. there were 10 males and 9 females with a median age of 61 years (range 42-76). the tumour was located in the choroid in 12 eyes and in the choroid and ciliary body in 7 eyes. the size of the tumours was 7-18 mm in maximal basal diameter (median 12), 5-16 mm in minimal basal diameter (median 10), and 5.5-15 mm in thickness (median 8.5). the volume of the tumours was 123-1890 mm3 (median 540). all tumours were cl ...	2006	1488887
[new data on m. ia. mudrov's role in the development of pathology in russia].		2006	1489276
tm.		2006	1489393
prospective audit of an extramucosal technique for intestinal anastomosis.		2006	1489437
updated evaluation of the activity of antibiotics in a burn centre.	the results of microbiological tests performed in a burns unit between january 1989 and december 1990 have been analysed. burn wound swabs and biopsies, blood cultures, central venous and urinary catheters, bronchial aspirates, pharyngeal swabs and faecal cultures for a total of 7950 examinations were considered. staph. aureus was the most frequently isolated bacterium, followed by staph. epidermidis, pseud. aeruginosa and e. coli. the antibiograms have shown a low efficacy rate of cephalosporin ...	2006	1489502
[what we forgot in equal rights activities].		2006	1489598
ga-67 citrate scan in vascular graft infection.	the clinical utility of the ga-67 scan has been studied in 9 patients with clinical suspicion of vascular graft infection. eleven grafts were analyzed: 4 aortobifemoral, 2 iliofemoral, 3 femoropopliteal, 1 axillofemoral, and 1 axillobifemoral. the ga-67 scan was positive in 8 grafts with bacteriological proof of infection and negative in 3 grafts in which infection was ruled out by clinical follow-up. a ga-67 scan also demonstrated the spread of infection to the thigh in two patients and to the ...	2006	1489633
the influence of pigmentation and illumination on the perception of erythema.	the visual assessment of erythema induced by ultraviolet radiation (uvr) involves a comparison of the irradiated site with surrounding nonirradiated skin. by viewing the skin through plastic filters of varying shades of brown to simulate different degrees of pigmentation and under either incandescent or fluorescent lighting, we were able to examine the influence of pigmentation and illumination on the perception of erythema. illuminating the skin with either light source at the same illuminance ...	2006	1489713
in vitro kinetics of 8-methoxypsoralen penetration into human lymphoid cells.	extracorporeal photochemotherapy (ecpc) requires ex vivo uva irradiation of blood lymphocytes during the time of the theoretical peak 8-methoxsalen (8-mop) concentration. the aims of this study were to determine the mechanism of cellular uptake of 8-mop, its possible saturation and the time needed to reach maximal concentration (tmax) in lymphoid cells. 8-mop was measured by liquid chromatography in the supernatant of lymphoid cell suspensions incubated with a known amount of 8-mop. the kinetics ...	1992	1489716
comparison of the antipsoriatic efficacy of heliotherapy and ultraviolet b: a cross-over study.	ten psoriasis patients who underwent a 4-week heliotherapy period in the canary islands were treated with ultraviolet b (uvb) phototherapy at relapse, 2-24 months later. in both settings, psoriasis improvement was monitored using a psoriasis severity index (psi), and uv exposure was recorded with polysulphone films. in the 8 patients that could be evaluated, a median healing rate of 94% was recorded in the heliotherapy period, with a median cumulative uv dose of 46 erythemal units (eu). in the u ...	1992	1489722
nuclear transport and phosphorylation of the rna binding xenopus zinc finger protein xfg 5-1.	xfg 5-1 is a krüppel-type xenopus zinc finger protein with specific rna homopolymer binding activity in vitro. in the oocyte, the protein is distributed between nucleus and cytoplasm; the nuclear fraction, not the cytoplasm, contains phosphorylated isoform(s) of xfg 5-1. in vitro phosphorylation by use of oocyte/egg extracts or purified casein kinase ii is specific to the amino-terminal portion of the protein. the carboxy-terminal zinc finger domain contains a signal sufficient for nuclear trans ...	2006	1489726
proceedings of the stromberg (mainz, germany) meeting of the society for research into hydrocephalus and spina bifida, 1992.		2006	1489736
factors affecting the school placement of children with spina bifida.	integrating children with disabilities into mainstream schools has been an active policy in britain since the 1981 education act. 26 children with spina bifida, 13 of whom were educated in mainstream schools, and 13 in special schools were assessed to clarify the relative importance of the following factors 1) iq, 2) mobility, 3) hand function, 4) bladder and bowel function, and 5) behaviour. a marked difference was found between those attending mainstream and special schools. 11/13 of the forme ...	2006	1489742
dna adduct measurements and tumor incidence during chronic carcinogen exposure in animal models: implications for dna adduct-based human cancer risk assessment.		1992	1489923
distinct conformers of alkylchrysene diol epoxide-deoxyguanosine adducts detected by proton nmr.	proton nmr spectra, obtained in meoh-d4, of the major dna adduct of 5,7-dimethylchrysene-1,2-diol 3,4-epoxide, identified as 1(r),2(s),3(s)-trihydroxy-4(s)-(n2-deoxyguanosyl)-1, 2,3,4-tetrahydro-5,7-dimethylchrysene, showed the presence of two distinct conformers. one conformer, similar to those observed previously in spectra of peracetates of related dna adducts of anti-diol epoxides of polynuclear aromatic hydrocarbons, had a chair-like conformation of the tetrahydrobenzo ring. the other confo ...	2006	1489924
iec-18, a nontransformed small intestinal cell line for studying epithelial permeability.	small intestinal epithelium is leaky and allows permeation of hydrophilic molecules of various sizes. passively absorbed hydrophilic permeability probes have been shown to permeate across intestinal epithelium mainly through the paracellular pathways. in this study we introduce microporous filter-grown iec-18 epithelial cells, a nontransformed small intestinal cell line, as a in vitro model of intestinal epithelium for the study of epithelial permeability. iec-18 cells, originally derived from n ...	1992	1500831
switch recombination breakpoints are strictly correlated with dna recognition motifs for immunoglobulin s gamma 3 dna-binding proteins.	the deletion looping out model of switch (s) recombination predicts that the intervening dna between switch regions will be excised as a circle. circular excision products of immunoglobulin switch recombination have been recently isolated from lipopolysaccharide (lps)-stimulated spleen cells. the recombination breakpoints in these large circles were found to fall within switch regions. since switch recombination is clearly focused on switch regions, we hypothesized that some dna-binding protein ...	2006	1500850
perceptual interactions between musical pitch and timbre.	these experiments examined perceptual interactions between musical pitch and timbre. experiment 1, through the use of the garner classification tasks, found that pitch and timbre of isolated tones interact. classification times showed interference from uncorrelated variation in the irrelevant attribute and facilitation from correlated variation; the effects were symmetrical. experiments 2 and 3 examined how musical pitch and timbre function in longer sequences. in recognition memory tasks, a tar ...	2006	1500873
chemotherapy and surgery in a murine osteosarcoma.	surgical and chemotherapeutic effects on pulmonary metastatic disease were evaluated in the mgh-ogs murine osteosarcoma. the tumor responded to three sequential injections of doxorubicin with prolonged growth delay but cisplatin administration (although given in doses sufficient to cause weight loss and significant mortality) was not effective in controlling local disease progression. using a protocol with three injections of doxorubicin (0.006 mg/g of body weight), it was observed that disease- ...	2006	1500984
use of the polymerase chain reaction to isolate an s-locus glycoprotein cdna introgressed from brassica campestris into b. napus ssp. oleifera.	a self-incompatible canola-quality brassica napus ssp. oleifera line (w1) was generated by introgressing the s-locus from a self-incompatible b. campestris plant into the westar cultivar. using the polymerase chain reaction (pcr) with primers derived from conserved regions in s-locus glycoprotein (slg) alleles, the central region of the active slg gene (910) was obtained. the remaining portions of the cdna for this 910 gene were subsequently cloned using the pcr-rapid amplification of cdna ends ...	2006	1508146
[plasmid composition of yersinia pestis strains from different natural foci].	the study of the plasmid composition of 246 y. pestis strains from different natural foci in the ussr and other countries revealed that 173 strains (70%) carried three known plasmids with a molecular weight of about 6, 45-50 and 60 megadaltons (md) respectively. in 20 strains (8%) obtained from different sources additional cryptic plasmids were detected. in some cases the absence of one or two typical plasmids was observed. replicon ppst was shown to have quite constant molecular weight (6 md), ...	1992	1509839
serologic survey for selected arboviruses and other potential pathogens in wildlife from mexico.	during 1988 and 1989, a serologic survey of wildlife was conducted in northeastern mexico to determine the presence, prevalence, and distribution of arboviruses and other selected disease agents. eighty mammal specimens were tested. antibodies to vesicular stomatitis-indiana, venezuelan equine encephalitis-mena ii, rio grande virus, and vesicular stomatitis-new jersey were detected predominantly in small mammals. deer and mouflon (ovis musimon) had antibodies to bluetongue and epizootic hemorrha ...	1992	1512876
recursive rf excitation.	we have investigated the properties of a recursive process in which the output signal from a given rf excitation pulse may be used as the input (excitation) pulse of a subsequent iteration. this recursive excitation technique increases contrast and improves feature segmentation for the purpose of motion tracking.	2006	1513257
half-empty or half-full?: two responses to "elegy".		2006	1513380
nmr restraint analysis of transforming growth factor alpha: a key component for nmr structure refinement.	structures of the protein, transforming growth factor alpha (tgf-alpha), have been derived from nmr data using distance geometry and subsequent energy refinement. analysis of the sequential noe distance bounds using a template algorithm provides a check for consistency in the calculation of bounds, stereospecific assignment of prochiral centers, and secondary structure assignment. application of the template algorithm to the long range noes found within the nmr data sets collected at ph 6.3 and ...	2006	1518801
a convenient synthesis of n-succinimidyl-3-iodo-[125i]benzoate, a reagent for protein iodination.	a convenient procedure has been developed for the synthesis of n-succinimidyl-3-iodo-[125i]benzoate. the procedure involved the synthesis of chloromercuribenzoic acid, its esterification with n-hydroxysuccinimide (nhs) and exchanging the mercury moiety with radioactive iodine in the presence of an oxidant. the obtained product was attached to human serum albumin and its stability was compared with chloramine-t (ch-t) radioiodinated protein. the results indicated that the reagent-radiolabeled pro ...	1992	1522025
the influence of the stomach on crop function and feeding behavior in domestic turkeys.	we tested the hypotheses that motility of the crop and muscular stomach are coordinated and that the stomach exerts primary control over crop filling and emptying in domestic turkeys. simultaneous recordings of motility of the crop, esophagus, and stomach with implanted strain gauge transducers and visual observations of food passage using image intensification radiography revealed an inverse relationship between the frequency of stomach and crop contractions. artificially filling the stomach of ...	1992	1523251
comparison of totally implanted and external catheters in paediatric oncology patients.	from june 1982 until december 1989, 93 permanent central venous catheters [59 external catheters (ecs) and 34 implanted catheters (ics)] were placed in 69 patients. the median age of these patients at placement was 5.6 years for ecs and 8.8 years for ics (p less than 0.05). follow-up evaluation was possible on 86 catheters (58 ecs and 28 ics). the median time of insertion was 236 days and 316 days for ecs and ics, respectively (p less than 0.05). the median number of open days was 58 for ecs and ...	2006	1524904
carbohydrate specificity of the receptor sites of mistletoe toxic lectin-i.	the carbohydrate specificity of mistletoe toxic lectin-i (ml-i) was studied by haemagglutination-inhibition assay. the results indicated that ml-i has a broad range of affinity for gal alpha,beta linked sequences. the galabiose (e, gal alpha 1----4gal) sequence, a receptor of the uropathogenic e. coli ligand, was one of the best disaccharide inhibitors tested. the lectin also exhibits affinity for lac(gal beta 1----4glc), t(gal beta 1----3galnac), i/ii(gal beta 1----3/4glcnac) and b(gal alpha 1- ...	2006	1525184
germ-line therapy: evolutionary and moral considerations.		2006	1525208
article of shaham and coworkers ("methadone maintenance" volume 28, number 3, 1991)		2006	1526758
adhesive properties conferred by the plasminogen activator of yersinia pestis.	a genomic library of yersinia pestis ev76c created in a cosmid vector was screened for clones capable of binding type iv collagen. an unexpectedly high number of such clones was observed. one recombinant plasmid was selected for further study, and the locus controlling collagen binding was mapped by subcloning, transposon mutagenesis and exonuclease digestion. the outer-membrane protein profiles of transposon insertion mutants were correlated with phenotype to implicate a 36 kda polypeptide in t ...	1992	1527508
[thymidine phosphorylase activity and its relationship to trimethoprim in initial strains and thymidine-, thymine-dependent and trimethoprim-resistant mutants of plague microbe].	the comparative study revealed thymidine phosphorylase activity in the initial strains of a plague microbe of the field variety and in thymidine-, thymine-dependent and trimethoprim-resistant mutants of the plague microbe of other varieties. the data fully conformed to the results of the microbiological investigation of the strains' ability to grow on the nutrient media with trimethoprim in the presence of thymine and thymidine. on the basis of these results it appeared possible to divide the in ...	1992	1530352
effects of celiprolol on cardiovascular reactivity to laboratory stressors in patients with hypertension.	an ideal antihypertensive drug should reduce blood pressure not only at rest but also during stressful situations. to test whether this criterion is fulfilled by celiprolol, a new beta 1-selective adrenergic blocker drug with peripheral vasodilating activity, we examined the effects of its oral administration on cardiovascular reactivity to laboratory stressors in 18 patients with essential hypertension, according to a placebo-controlled crossover design. in the 12 patients classified as "respon ...	2006	1534042
polymorphism in the rd (d6s45) gene.	the rd (d6s45) gene in the class iii region of the hla major histocompatibility complex encodes a protein normally containing 24 consecutive basic-acidic dipeptide repeats. we determined the frequency of variations in the number of repeats by use of the polymerase chain reaction. of 107 subjects 7 (3.3%) carried genes encoding 22 or 23 repeats. there was no difference in the frequency of such polymorphisms between normal individuals and those with systemic lupus erythematosus, a disease associat ...	1992	1534063
better right than quick?		2006	1538635
[the role of dna probes in the diagnosis of bacterial infections].		2006	1538798
pancreatic pleural effusion: case report and review of 113 cases in japan.	a patient with pancreatic pleural effusion in whom a fistulous tract was demonstrated by computed tomography (ct) is presented, and reports on 113 cases of this entity in the japanese literature are reviewed. the most common (99%) underlying cause of this entity was chronic alcoholic pancreatitis. in most cases, the patients complained of chest symptoms (68%), and complained of abdominal symptoms less frequently (24%). it is important to maintain suspicion for this entity in patients with chroni ...	2006	1539580
whole cell patch clamping of ciliary epithelial cells during anisosmotic swelling.	anisosmotic cell swelling triggers a regulatory volume decrease (rvd) in cell lines derived from human nonpigmented ciliary epithelium. measurements of cell volume have indicated that the rvd reflects activation of k+ and/or cl- channels. we have begun to characterize the putative channels by whole cell patch clamping. the results obtained by altering the external k+ and cl- concentrations and by adding 20-50 microm quinidine or 1 mm ba2+ indicate that k+ conductances contribute substantially an ...	1992	1539636
needle exchange program reduces spread of aids.		2006	1539956
recommended practices. care of instruments, scopes, and powered surgical instruments.		2006	1539963
degradation of 2,4-dinitrotoluene by the lignin-degrading fungus phanerochaete chrysosporium.	under ligninolytic conditions, the white rot basidiomycete phanerochaete chrysosporium mineralizes 2,4-dinitrotoluene (i). the pathway for the degradation of i was elucidated by the characterization of fungal metabolites and oxidation products generated by lignin peroxidase (lip), manganese peroxidase (mnp), and crude intracellular cell extracts. the multistep pathway involves the initial reduction of i to yield 2-amino-4-nitrotoluene (ii). ii is oxidized by mnp to yield 4-nitro-1,2-benzoquinone ...	1992	1539977
interactions between marine bacteria and dissolved-phase and beached hydrocarbons after the exxon valdez oil spill.	turnover times for toluene in resurrection bay after the exxon valdez grounding were determined to be decades, longer than expected considering that dissolved hydrocarbons were anticipated to drift with the current and stimulate development of additional hydrocarbon-utilizing capacity among the microflora in that downcurrent location. these turnover times were based on the recovery of 14co2 from added [14c]toluene that was oxidized. the concentrations of toluene there, 0.1 to 0.2 microgram/liter ...	2006	1539978
prophylaxis against non-steroidal induced upper gastrointestinal side effects.		2006	1540028
idiopathic myositis: a rheumatological view.	twenty five patients with idiopathic myositis attended this department for long term follow up from 1980 to 1989. twelve patients had primary polymyositis (four men, eight women) and six had primary dermatomyositis (three men, three women); five women had an overlap syndrome. two patients had a malignant condition associated with the myositis. the mean age at diagnosis was 40 years. all of the patients had proximal muscle weakness, 18/25 had a raised creatine kinase value (mean 2325 iu/l), 19/20 ...	2006	1540036
radiographic assessment of the knee joint in osteoarthritis.	the development of radiographic systems for the grading of osteoarthritis requires knowledge of the reproducibility of their individual component features. this paper reports the reproducibility, both within and between observers, for five commonly used radiographic features of osteoarthritis in the tibiofemoral and patellofemoral compartments of the knee joint. the results suggest that assessments of joint space narrowing, osteophyte, and bony contour in the tibiofemoral compartments are more r ...	2006	1540044
immune complexes in ankylosing spondylitis.	immune complexes have been reported in ankylosing spondylitis (as) and may implicate infectious agents. serum samples from 49 patients with as were assayed for immune complexes by polyethylene glycol precipitation, followed by radial immunodiffusion and pepsinogen binding immunoassay. both methods showed increases in iga containing immune complexes, which correlated with serum iga and with iga rheumatoid factor concentrations, but did not show increases in other immune complex components. increa ...	1992	1540045
effects of cardioplegic solutions and their components on human saphenous vein contractility.	cardioplegic solution administration into the vein graft is an established method to ensure cardioplegic distribution beyond coronary artery stenoses. the ultrastructural demonstration of severe endothelial damage after cardioplegic exposure suggests that intravenous cardioplegic administration can contribute to early and late graft thrombosis. the direct effect on human saphenous vein contractility of three cardioplegic solutions and their components was compared. a solution with 30 mmol/l k+ a ...	1992	1540064
acute postinfarction septal rupture: long-term results.		2006	1540087
the role of neck dissection in thoracic esophageal cancer.		2006	1540089
[calculation of visit fees and travel expense by free-practicing anesthetists. decision of the münster ovg on l2/l8/1990].		2006	1544356
bubonic plague.	a 19-year-old man, recently returned from a 10-day military exercise in central california, had acute onset of shaking chills, headache, and bilateral inguinal adenopathy after having been bitten by insects on his lower extremities. he had exquisitely tender inguinal and femoral nodes bilaterally. needle aspirate from an inguinal node grew yersinia pestis. the patient was treated with streptomycin and chloramphenicol and did well.	1992	1546359
contribution of inherited factors to rheumatoid arthritis.	a total of 231 sibships of the same sex (186 female, 45 male), in which the proband had classical or definite rheumatoid arthritis (ra) have been selected from rheumatology clinics. each sibship member was questioned about symptomatic joints, which were then examined. hospital records, radiographs, and rheumatoid factor measurements allowed each sibling to be classified as having classical, definite, probable, or no ra. each sibling was typed for hla-a and b and was classified as sharing two, on ...	2006	1550401
a new gene of the f1 operon of y. pestis involved in the capsule biogenesis.	the dna sequence determination of the f1 operon between the genes encoding the f1 subunit (caf1) and chaperone-like protein (caf1m) revealed a large open reading frame that codes for a polypeptide similar to some e. coli proteins involved in the biogenesis of fimbria. the deletion and in trans complementation analyses showed that this gene is not necessary for extracellular transport of the f1 subunit but plays a role in the capsule assembly.	1992	1551441
determination of genome size, macrorestriction pattern polymorphism, and nonpigmentation-specific deletion in yersinia pestis by pulsed-field gel electrophoresis.	of 16 restriction endonucleases known to hydrolyze rare 6- or 8-base recognition sequences that were tested, only spei, noti, asci, and sfii generated fragments of chromosomal dna from yersinia pestis, the causative agent of bubonic plague, of sufficient length to permit physical analysis by pulsed-field gel electrophoresis (pfge). of the individual bands detected after single-dimensional pfge of these digests, the largest sum was obtained with spei (3,575.6 +/- 114.6 kb). of these 41 bands, 3 w ...	1992	1551830
angioplasty of a totally occluded right coronary artery.	we have presented a case of angioplasty of a chronically occluded right coronary artery. the occlusion had been present for 6 wks by clinical estimates. the length of the occluded segment (approximately 55 cm) did not preclude a successful outcome. proper selection and manipulation of angioplasty equipment are, as in every case, critical for procedural success. subintimal guidewire passage, though a frequent event, is occasionally associated with ischemic manifestations, and mandates detection a ...	1981	1555228