Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| indirect effects of cigarette butt waste on the dengue vector aedes aegypti (diptera: culicidae). | despite major insecticide-based vector control programs, dengue continues to be a major threat to public health in urban areas. the reasons for this failure include the emergence of insecticide resistance and the narrowing of the spectrum of efficient products. cigarette butts (cbs), the most commonly discarded piece of waste, also represent a major health hazard to human and animal life. cbs are impregnated with thousands of chemical compounds, many of which are highly toxic and none of which h ... | 2014 | 24239749 |
| vector population manipulation for control of arboviruses--a novel prospect for india. | india, the seventh largest country in the world, has diverse geographical and climatic regions with vast rural and peri-urban areas. many are experiencing an escalation in the spread and intensity of numerous human diseases transmitted by insects. classically, the management of these vector-borne diseases is underpinned by either chemical insecticides and/or environmental management targeted at the vector. however, these methods or their present implementation do not offer acceptable levels of c ... | 2014 | 24254373 |
| characterising the spatial dynamics of sympatric aedes aegypti and aedes albopictus populations in the philippines. | entomological surveillance and control are essential to the management of dengue fever (df). hence, understanding the spatial and temporal patterns of df vectors, aedes (stegomyia) aegypti (l.) and ae. (stegomyia) albopictus (skuse), is paramount. in the philippines, resources are limited and entomological surveillance and control are generally commenced during epidemics, when transmission is difficult to control. recent improvements in spatial epidemiological tools and methods offer opportuniti ... | 2013 | 24258900 |
| novel histopathological and molecular effects of natural compound pellitorine on larval midgut epithelium and anal gills of aedes aegypti. | the yellow fever mosquito, aedes aegypti, is a vector for transmitting dengue fever and yellow fever. in this study, we assessed the histopathological and molecular effects of pellitorine, an isobutylamide alkaloid, on the third instar of ae. aegypti larvae. at 5 mg/l concentration of pellitorine, the whole body of the treated larvae became dark in color, particularly damaged thorax and abdominal regions. pellitorine was targeted mainly on midgut epithelium and anal gills, indicating variably dr ... | 2013 | 24260359 |
| essential oils and their compounds as aedes aegypti l. (diptera: culicidae) larvicides: review. | this review aims to describe essential oils and their constituent compounds that exhibit bioactivity against aedes aegypti l. (diptera: culicidae) larvae, the immature stage of the primary vector of dengue. this review is based on original articles obtained by searching on major databases. our literature review revealed that 361 essential oils from 269 plant species have been tested for their larvicidal activity. more than 60 % of these essential oils were considered active (lc50<100 mg/l), and ... | 2014 | 24265058 |
| larvicidal activity of mentha x villosa hudson essential oil, rotundifolone and derivatives. | the aim of this study was to evaluate the larvicidal activity of mentha x villosa essential oil (mveo) and its major constituent, rotundifolone, against larvae of aedes aegypti. additionally, a set of 15 analogues of the rotundifolone were evaluated to identify the molecular characteristics which contribute to the larvicidal effect. the results from the present study showed that the mveo exhibited outstanding toxic effects against ae. aegypti larvae (lc50=45.0ppm). rotundifolone exhibited reason ... | 2014 | 24275151 |
| susceptibility status of aedes aegypti (l.) (diptera: culicidae) to temephos in venezuela. | temephos is an insecticide widely used in venezuela to control the proliferation of the larvae of aedes aegypti (l.), the principal vector of dengue virus. the aim of this study was to identify the susceptibility to temephos of ae. aegypti in four locations in western venezuela: lara, tres esquinas, ureña and pampanito. larval bioassays were conducted on samples collected in 2008 and 2010, and the levels of α- and β-esterases, mixed-function oxidases, glutathione-s-transferase and insensitive ac ... | 2014 | 24282132 |
| [risk factors associated to the epidemic outbreak of dengue virus infection.] | objective: to identify the risk factors associated to the epidemic of dengue virus infections occurred at queretaro, mexico. methods: a case-control study was carried out on 49 cases and 49 controls. the data included: age, sex, residency, schooling, occupation, clinical data, sources infected with aedes aegypti, travelling, source of waters, and protection to water recipients. the protection to door and windows was investigated. χ(2) test and odds ratio were estimated. results: the age group of ... | 2013 | 24290012 |
| synthesis, activity, and qsar studies of tryptamine derivatives on third-instar larvae of aedes aegypti linn. | special attention has been given to the mosquito aedes aegypti linn. (diptera: culicidae) owing to numerous dengue epidemic outbreaks worldwide. failure to control vector spreading is accounted for unorganized urban growth and resistance to larvicides and insecticides. therefore, researchers are currently searching for new and more efficient larvicides and insecticides to aid dengue control measures. triptamine is known to affect insect behavior, development, and physiology. expression of this c ... | 2014 | 24295020 |
| differential transcription profiles in aedes aegypti detoxification genes after temephos selection. | the mosquito aedes aegypti is the main vector of dengue and yellow fever flaviviruses. the organophosphate insecticide temephos is a larvicide that is used globally to control ae. aegypti populations; many of which have in turn evolved resistance. target site alteration in the acetylcholine esterase of this species has not being identified. instead, we tracked changes in transcription of metabolic detoxification genes using the ae. aegypti 'detox chip' microarray during five generations of temep ... | 2013 | 24299217 |
| use of anti-aedes aegypti salivary extract antibody concentration to correlate risk of vector exposure and dengue transmission risk in colombia. | norte de santander is a region in colombia with a high incidence of dengue virus (denv). in this study, we examined the serum concentration of anti-aedes salivary gland extract (sge) antibodies as a biomarker of denv infection and transmission, and assessed the duration of anti-sge antibody concentration after exposure to the vector ceased. we also determined whether sge antibody concentration could differentiate between positive and negative denv infected individuals and whether there are diffe ... | 2013 | 24312537 |
| innate immunity to dengue virus infection and subversion of antiviral responses. | dengue is a major public health issue in tropical and subtropical regions worldwide. the four serotypes of dengue virus (denv1-denv4) are spread primarily by aedes aegypti and aedes albopictus mosquitoes, whose geographic range continues to expand. humans are the only host for epidemic strains of denv, and the virus has developed sophisticated mechanisms to evade human innate immune responses. the host cell's first line of defense begins with an intracellular signaling cascade resulting in produ ... | 2013 | 24316047 |
| larvicidal, ovicidal, and adulticidal efficacy of erythrina indica (lam.) (family: fabaceae) against anopheles stephensi, aedes aegypti, and culex quinquefasciatus (diptera: culicidae). | mosquitoes are the major vector for the transmission of malaria, dengue fever, yellow fever, filariasis, schistosomiasis, and japanese encephalitis. mosquito control is facing a threat because of the emergence of resistance to synthetic insecticides. insecticides of botanical origin may serve as suitable alternative biocontrol techniques in the future. in view of the recently increased interest in developing plant origin insecticides as an alternative to chemical insecticide, this study was unde ... | 2014 | 24322290 |
| dengue vector dynamics (aedes aegypti) influenced by climate and social factors in ecuador: implications for targeted control. | dengue fever, a mosquito-borne viral disease, is now the fastest spreading tropical disease globally. previous studies indicate that climate and human behavior interact to influence dengue virus and vector (aedes aegypti) population dynamics; however, the relative effects of these variables depends on local ecology and social context. we investigated the roles of climate and socio-ecological factors on ae. aegypti population dynamics in machala, a city in southern coastal ecuador where dengue is ... | 2013 | 24324542 |
| proteomic identification of dengue virus binding proteins in aedes aegypti mosquitoes and aedes albopictus cells. | the main vector of dengue in america is the mosquito aedes aegypti, which is infected by dengue virus (denv) through receptors of midgut epithelial cells. the envelope protein (e) of dengue virus binds to receptors present on the host cells through its domain iii that has been primarily recognized to bind cell receptors. in order to identify potential receptors, proteins from mosquito midgut tissue and c6/36 cells were purified by affinity using columns with the recombinant e protein domain iii ... | 2013 | 24324976 |
| modelling adult aedes aegypti and aedes albopictus survival at different temperatures in laboratory and field settings. | the survival of adult female aedes mosquitoes is a critical component of their ability to transmit pathogens such as dengue viruses. one of the principal determinants of aedes survival is temperature, which has been associated with seasonal changes in aedes populations and limits their geographical distribution. the effects of temperature and other sources of mortality have been studied in the field, often via mark-release-recapture experiments, and under controlled conditions in the laboratory. ... | 2013 | 24330720 |
| evolution of dengue in sri lanka-changes in the virus, vector, and climate. | despite the presence of dengue in sri lanka since the early 1960s, dengue has become a major public health issue, with a high morbidity and mortality. aedes aegypti and aedes albopictus are the vectors responsible for the transmission of dengue viruses (denv). the four denv serotypes (1, 2, 3, and 4) have been co-circulating in sri lanka for more than 30 years. the new genotype of denv-1 has replaced an old genotype, and new clades of denv-3 genotype iii have replaced older clades. the emergence ... | 2014 | 24334026 |
| competition for amino acids between wolbachia and the mosquito host, aedes aegypti. | the endosymbiont wolbachia represents a promising method of dengue control, as it reduces the ability of the primary vector, the mosquito aedes aegypti, to transmit viruses. when mosquitoes infected with the virulent wolbachia strain wmelpop are fed non-human blood, there is a drastic reduction in mosquito fecundity and egg viability. wolbachia has a reduced genome and is clearly dependent on its host for a wide range of nutritional needs. the fitness defects seen in wmelpop-infected a. aegypti ... | 2014 | 24337107 |
| larvicidal potential of silver nanoparticles synthesized from leucas aspera leaf extracts against dengue vector aedes aegypti. | vector-borne diseases caused by mosquitoes are one of the major economic and health problems in many countries. aedes aegypti mosquito is a vector of several diseases in humans like yellow fever and dengue. vector control methods involving use of chemical insecticides are becoming less effective due to the development of insecticides resistance, biological magnification of toxic substances through the food chain, and adverse effects on environmental quality and nontarget organisms including huma ... | 2014 | 24337613 |
| aedes aegypti entomological indices in an endemic area for dengue in sao paulo state, brazil. | to evaluate the most productive types of properties and containers for aedes aegypti and the spatial distribution of entomological indices. | 2013 | 24346572 |
| metarhizium anisopliae pathogenesis of mosquito larvae: a verdict of accidental death. | metarhizium anisopliae, a fungal pathogen of terrestrial arthropods, kills the aquatic larvae of aedes aegypti, the vector of dengue and yellow fever. the fungus kills without adhering to the host cuticle. ingested conidia also fail to germinate and are expelled in fecal pellets. this study investigates the mechanism by which this fungus adapted to terrestrial hosts kills aquatic mosquito larvae. genes associated with the m. anisopliae early pathogenic response (proteinases pr1 and pr2, and adhe ... | 2013 | 24349111 |
| the relationship between economic status, knowledge on dengue, risk perceptions and practices. | the reemergence of dengue as an important public health problem reflects the difficulties in sustaining vertically organized, effective, control programs and the need for community-based strategies for aedes aegypti control that result in behavioral change. we aimed to disentangle the relationships between underlying determinants of dengue related practices. we conducted a cross-sectional study in 780 households in la lisa, havana, cuba. a questionnaire and an observation guide were administrate ... | 2013 | 24349145 |
| wolbachia interferes with the intracellular distribution of argonaute 1 in the dengue vector aedes aegypti by manipulating the host micrornas. | argonaute proteins (agos) are vital components of the rna-induced silencing complex in gene silencing. agos are indispensable for microrna (mirna) biogenesis as well as function, and are intracellularly localized to both the cytoplasm and the nucleus. cytoplasmic ago-mirna complexes are mainly involved in cleavage or translational repression of target mrnas while the nuclear ones are engaged in transcriptional gene silencing, methylation, chromatin remodeling, and splicing. in insects, ago1 and ... | 2013 | 24351659 |
| effect of mycosynthesized silver nanoparticles from filtrate of trichoderma harzianum against larvae and pupa of dengue vector aedes aegypti l. | mosquitoes transmit dreadful diseases, causing millions of deaths every year. therefore, screening for larvicidal and pupicidal activity of microbial extracts attributes could lead to development of new and improved mosquito control methods that are economical and safe for nontarget organisms and are ecofriendly. synthetic chemical insecticides occupy predominant position in control strategies. these hazardous chemicals exert unwarranted toxicity and lethal effects on nontarget organisms, develo ... | 2014 | 24352539 |
| apropos "vaccination for safe travel to india". | 2013 | 24356443 | |
| is there a risk of yellow fever virus transmission in south asian countries with hyperendemic dengue? | the fact that yellow fever (yf) has never occurred in asia remains an "unsolved mystery" in global health. most countries in asia with high aedes aegypti mosquito density are considered "receptive" for yf transmission. recently, health officials in sri lanka issued a public health alert on the potential spread of yf from a migrant group from west africa. we performed an extensive review of literature pertaining to the risk of yf in sri lanka/south asian region to understand the probability of ac ... | 2013 | 24367789 |
| expression and accumulation of the two-domain odorant-binding protein aaegobp45 in the ovaries of blood-fed aedes aegypti. | aedes aegypti mosquitoes are the main vectors of dengue viruses. despite global efforts to reduce the prevalence of dengue using integrated vector management strategies, innovative alternatives are necessary to help prevent virus transmission. detailed characterizations of ae. aegypti genes and their products provide information about the biology of mosquitoes and may serve as foundations for the design of new vector control methods. | 2013 | 24367904 |
| aedes aegypti from temperate regions of south america are highly competent to transmit dengue virus. | aedes aegypti is extensively spread throughout south america where it has been responsible for large dengue epidemics during the last decades. intriguingly, dengue transmission has not been reported in uruguay and is essentially prevalent in subtropical northern argentina which borders uruguay. | 2013 | 24373423 |
| a reduce and replace strategy for suppressing vector-borne diseases: insights from a stochastic, spatial model. | two basic strategies have been proposed for using transgenic aedes aegypti mosquitoes to decrease dengue virus transmission: population reduction and population replacement. here we model releases of a strain of ae. aegypti carrying both a gene causing conditional adult female mortality and a gene blocking virus transmission into a wild population to assess whether such releases could reduce the number of competent vectors. we find this "reduce and replace" strategy can decrease the frequency of ... | 2013 | 24376506 |
| reduction in dengue cases observed during mass control of aedes (stegomyia) in street catch basins in an endemic urban area in colombia. | dengue incidence continues to increase globally and, in the absence of an efficacious vaccine, prevention strategies are limited to vector control. it has been suggested that targeting the most productive breeding sites instead of all water-holding containers could be a cost-effective vector control strategy. we sought to identify and continuously control the most productive aedes (stegomyia) breeding site in an endemic urban area in colombia and followed the subsequent incidence of dengue. in t ... | 2014 | 24388794 |
| severe oral manifestation of dengue viral infection: a rare clinical description. | dengue infection is one of the most common mosquito-borne viral diseases of humans worldwide, representing a significant public health problem in over 100 tropical countries where its primary vector aedes aegypti occurs. although the disease is frequently limited to an abrupt febrile illness, it may also cause significant morbidity and if not adequately treated, mortality. therefore, it requires a correct and early diagnosis. oral manifestations of dengue infection are commonly reported as gingi ... | 2014 | 24389569 |
| comparative susceptibility of mosquito populations in north queensland, australia to oral infection with dengue virus. | dengue is the most prevalent arthropod-borne virus, with at least 40% of the world's population at risk of infection each year. in australia, dengue is not endemic, but viremic travelers trigger outbreaks involving hundreds of cases. we compared the susceptibility of aedes aegypti mosquitoes from two geographically isolated populations to two strains of dengue virus serotype 2. we found, interestingly, that mosquitoes from a city with no history of dengue were more susceptible to virus than mosq ... | 2014 | 24420782 |
| distribution and dissemination of the val1016ile and phe1534cys kdr mutations in aedes aegypti brazilian natural populations. | the chemical control of the mosquito aedes aegypti, the major vector of dengue, is being seriously threatened due to the development of pyrethroid resistance. substitutions in the 1016 and 1534 sites of the voltage gated sodium channel (aanav), commonly known as kdr mutations, confer the mosquito with knockdown resistance. our aim was to evaluate the allelic composition of natural populations of brazilian ae. aegypti at both kdr sites. | 2014 | 24428880 |
| comparative field efficacy of newly developed formulations of larvicides against aedes aegypti (l.) (diptera: culicidae). | aedes aegypti (l.) is known as vector of dengue and chikungunya fever. larvicides are used to control this vector. we evaluated the efficacy of newly developed formulations of larvicides to control ae. aegypti under field conditions for 24 weeks post single application. mosdop p and mosdop tb containing diflubenzuron (2% and 40 mg/tablet, respectively) as the active ingredient, were applied at a dosage of 0.1 mg a.i./1 and mosquit tb10, mosquit tb100 and temecal containing temephos (1%, 10% and ... | 2013 | 24437310 |
| effect of dengue-2 virus infection on protein expression in the salivary glands of aedes aegypti mosquitoes. | dengue virus (denv) is the most important mosquito-transmitted flavivirus that is transmitted throughout the tropical and subtropical regions of the world. the primary mosquito vector of denv in urban locations is aedes aegypti. key to understanding the transmission of denv is the relationship between pathogen and vector. accordingly, we report our preliminary characterization of the differentially expressed proteins from ae. aegypti mosquitoes after denv infection. we investigated the virus-vec ... | 2014 | 24445208 |
| ecological, biological and social dimensions of dengue vector breeding in five urban settings of latin america: a multi-country study. | dengue is an increasingly important public health problem in most latin american countries and more cost-effective ways of reducing dengue vector densities to prevent transmission are in demand by vector control programs. this multi-centre study attempted to identify key factors associated with vector breeding and development as a basis for improving targeted intervention strategies. | 2014 | 24447796 |
| recent and future environmental suitability to dengue fever in brazil using species distribution model. | dengue fever is a mosquito-borne disease that affects more than 2.5 billion people worldwide. here, we used the dataset of municipality infestation level from the brazilian health ministry with the aim of building vector distribution models to identify epidemiological hotspots. | 2014 | 24463584 |
| the heterodimeric glycoprotein hormone, gpa2/gpb5, regulates ion transport across the hindgut of the adult mosquito, aedes aegypti. | a family of evolutionarily old hormones is the glycoprotein cysteine knot-forming heterodimers consisting of alpha- (gpa) and beta-subunits (gpb), which assemble by noncovalent bonds. in mammals, a common glycoprotein hormone alpha-subunit (gpa1) pairs with unique beta-subunits that establish receptor specificity, forming thyroid stimulating hormone (gpa1/tshβ) and the gonadotropins luteinizing hormone (gpa1/lhβ), follicle stimulating hormone (gpa1/fshβ), choriogonadotropin (gpa1/cgβ). a novel g ... | 2014 | 24466069 |
| aedes aegypti on madeira island (portugal): genetic variation of a recently introduced dengue vector. | the increasing population of aedes aegypti mosquitoes on madeira island (portugal) resulted in the first autochthonous dengue outbreak, which occurred in october 2012. our study establishes the first genetic evaluation based on the mitochondrial dna (mtdna) genes [cytochrome oxidase subunit i (coi) and nadh dehydrogenase subunit 4 (nd4)] and knockdown resistance (kdr) mutations exploring the colonisation history and the genetic diversity of this insular vector population. we included mosquito po ... | 0 | 24473797 |
| history of domestication and spread of aedes aegypti--a review. | the adaptation of insect vectors of human diseases to breed in human habitats (domestication) is one of the most important phenomena in medical entomology. considerable data are available on the vector mosquito aedes aegypti in this regard and here we integrate the available information including genetics, behaviour, morphology, ecology and biogeography of the mosquito, with human history. we emphasise the tremendous amount of variation possessed by ae. aegypti for virtually all traits considere ... | 0 | 24473798 |
| male accessory gland substances from aedes albopictus affect the locomotor activity of aedes aegypti females. | dengue is one of the world's most important mosquito-borne diseases and is usually transmitted by one of two vector species: aedes aegypti or aedes albopictus . these two diurnal mosquitoes are frequently found coexisting in similar habitats, enabling interactions between adults, such as cross-mating. the objective of this study was to assess cross-mating between ae. aegypti females and ae. albopictus males under artificial conditions and evaluate the locomotor activity of ae. aegypti virgin fem ... | 0 | 24473799 |
| aedes aegypti mos20 cells internalizes cry toxins by endocytosis, and actin has a role in the defense against cry11aa toxin. | bacillus thuringiensis (bt) cry toxins are used to control aedes aegypti, an important vector of dengue fever and yellow fever. bt cry toxin forms pores in the gut cells, provoking larvae death by osmotic shock. little is known, however, about the endocytic and/or degradative cell processes that may counteract the toxin action at low doses. the purpose of this work is to describe the mechanisms of internalization and detoxification of cry toxins, at low doses, into mos20 cells from a. aegypti, f ... | 2014 | 24476709 |
| distribution of mosquito larvae on kosrae island, kosrae state, the federated states of micronesia. | surveys of mosquito larvae were carried out in six areas of kosrae island, kosrae state, the federated states of micronesia in december 2009 and june 2012. a total of 962 larvae of six species were collected from 106 natural and artificial habitats. they were identified as aedes aegypti, ae. albopictus, ae. marshallensis, culex quinquefasciatus, cx. annulirostris, and cx. kusaiensis. this is the first report from kosrae island for three of these species-ae. marshallensis, cx. quinquefasciatus, a ... | 2013 | 24478593 |
| evidence for gene duplication in the voltage-gated sodium channel gene of aedes aegypti. | mutations in the voltage-gated sodium channel gene (nav), known as kdr mutations, are associated with pyrethroid and ddt insecticide resistance in a number of species. in the mosquito dengue vector aedes aegypti, besides kdr, other polymorphisms allowed grouping aanav sequences as type 'a' or 'b'. here, we point a series of evidences that these polymorphisms are actually involved in a gene duplication event. | 2013 | 24481195 |
| wolbachia versus dengue: evolutionary forecasts. | a novel form of biological control is being applied to the dengue virus. the agent is the maternally transmitted bacterium wolbachia, naturally absent from the main dengue vector, the mosquito aedes aegypti. three wolbachia-based control strategies have been proposed. one is suppression of mosquito populations by large-scale releases of males incompatible with native females; this intervention requires ongoing releases. the other interventions transform wild mosquito populations with wolbachia t ... | 2013 | 24481199 |
| ovicidal, larvicidal and adulticidal properties of asparagus racemosus (willd.) (family: asparagaceae) root extracts against filariasis (culex quinquefasciatus), dengue (aedes aegypti) and malaria (anopheles stephensi) vector mosquitoes (diptera: culicidae). | several diseases are associated to the mosquito-human interaction. mosquitoes are the carriers of severe and well-known illnesses such as malaria, arboviral encephalitis, dengue fever, chikungunya fever, west nile virus and yellow fever. these diseases produce significant morbidity and mortality in humans and livestock around the world. the present investigation was undertaken to study the ovicidal, larvicidal and adulticidal activities of crude hexane, ethyl acetate, benzene, chloroform and met ... | 2014 | 24488078 |
| identification of germline transcriptional regulatory elements in aedes aegypti. | the mosquito aedes aegypti is the principal vector for the yellow fever and dengue viruses, and is also responsible for recent outbreaks of the alphavirus chikungunya. vector control strategies utilizing engineered gene drive systems are being developed as a means of replacing wild, pathogen transmitting mosquitoes with individuals refractory to disease transmission, or bringing about population suppression. several of these systems, including medea, ud(mel), and site-specific nucleases, which c ... | 2014 | 24492376 |
| assessing quality of life-shortening wolbachia-infected aedes aegypti mosquitoes in the field based on capture rates and morphometric assessments. | recent releases have been carried out with aedes aegypti mosquitoes infected with the wmelpop mosquito cell-line adapted (wmelpop-cla) strain of wolbachia. this infection introduced from drosophila provides strong blockage of dengue and other arboviruses but also has large fitness costs in laboratory tests. the releases were used to evaluate the fitness of released infected mosquitoes, and (following termination of releases) to test for any effects of wmelpop-cla on wing size and shape when mosq ... | 2014 | 24495395 |
| temperature, larval diet, and density effects on development rate and survival of aedes aegypti (diptera: culicidae). | many environmental factors, biotic and abiotic interact to influence organismal development. given the importance of aedes aegypti as a vector of human pathogens including dengue and yellow fever, understanding the impact of environmental factors such as temperature, resource availability, and intraspecific competition during development is critical for population control purposes. despite known associations between developmental traits and factors of diet and density, temperature has been consi ... | 2014 | 24498328 |
| assembly of the genome of the disease vector aedes aegypti onto a genetic linkage map allows mapping of genes affecting disease transmission. | the mosquito aedes aegypti transmits some of the most important human arboviruses, including dengue, yellow fever and chikungunya viruses. it has a large genome containing many repetitive sequences, which has resulted in the genome being poorly assembled - there are 4,758 scaffolds, few of which have been assigned to a chromosome. to allow the mapping of genes affecting disease transmission, we have improved the genome assembly by scoring a large number of snps in recombinant progeny from a cros ... | 2014 | 24498447 |
| the susceptibility of aedes aegypti populations displaying temephos resistance to bacillus thuringiensis israelensis: a basis for management. | aedes aegypti is the vector of dengue virus, and its control is essential to prevent disease transmission. among the agents available to control this species, biolarvicides based on bacillus thuringiensis serovar israelensis (bti) are an effective alternative to replace the organophosphate temephos for controlling populations that display resistance to this insecticide. the major goal of this study was to determine the baseline susceptibility of brazilian ae. aegypti populations to bti, taking i ... | 2013 | 24499507 |
| oviposition and olfaction responses of aedes aegypti mosquitoes to insecticides. | insecticide applications are not particularly effective on aedes aegypti mosquitoes which has been attributed to their 'closet' behaviour, or ability to rest in places that remain unexposed to insecticides. some researchers have suggested that insecticides repel mosquitoes, which would result in less exposure and increased dispersal. if repellence due to insecticides is a fact, acquiring a vector-borne disease, such as dengue, could legitimately be attributed to local vector control efforts and ... | 2013 | 24522139 |
| genetic control of aedes aegypti: data-driven modelling to assess the effect of releasing different life stages and the potential for long-term suppression. | control of the world's most important vector-borne viral disease, dengue, is a high priority. a lack of vaccines or effective vector control methods means that novel solutions to disease control are essential. the release of male insects carrying a dominant lethal (ridl) is one such approach that could be employed to control aedes aegypti. to maximise the potential of ridl control, optimum release strategies for transgenic mosquitoes are needed. the use of field data to parameterise models allow ... | 2014 | 24524678 |
| microrna-like viral small rna from dengue virus 2 autoregulates its replication in mosquito cells. | micrornas (mirnas) are small regulatory rnas that play significant roles in most cellular processes. in the seemingly endless arms race between hosts and pathogens, viruses also encode mirnas that facilitate successful infection. in search of functional mirnas or viral small rnas (vsrnas) encoded by dengue virus (denv), deep sequencing data of virus-infected aedes aegypti mosquitoes were used. from six vsrnas, with candidate stem-loop structures in the 5' and 3' untranslated regions of the viral ... | 2014 | 24550303 |
| transmission-blocking antibodies against mosquito c-type lectins for dengue prevention. | c-type lectins are a family of proteins with carbohydrate-binding activity. several c-type lectins in mammals or arthropods are employed as receptors or attachment factors to facilitate flavivirus invasion. we previously identified a c-type lectin in aedes aegypti, designated as mosquito galactose specific c-type lectin-1 (mosgctl-1), facilitating the attachment of west nile virus (wnv) on the cell membrane. here, we first identified that 9 a. aegypti mosgctl genes were key susceptibility factor ... | 2014 | 24550728 |
| adult survivorship of the dengue mosquito aedes aegypti varies seasonally in central vietnam. | the survival characteristics of the mosquito aedes aegypti affect transmission rates of dengue because transmission requires infected mosquitoes to survive long enough for the virus to infect the salivary glands. mosquito survival is assumed to be high in tropical, dengue endemic, countries like vietnam. however, the survival rates of wild populations of mosquitoes are seldom measured due the difficulty of predicting mosquito age. hon mieu island in central vietnam is the site of a pilot release ... | 2014 | 24551251 |
| determinants of heterogeneous blood feeding patterns by aedes aegypti in iquitos, peru. | heterogeneous mosquito biting results in different individuals in a population receiving an uneven number of bites. this is a feature of many vector-borne disease systems that, if understood, could guide preventative control efforts toward individuals who are expected to contribute most to pathogen transmission. we aimed to characterize factors determining biting patterns of aedes aegypti, the principal mosquito vector of dengue virus. | 2014 | 24551262 |
| vertical infestation of the dengue vectors aedes aegypti and aedes albopictus in apartments in kuala lumpur, malaysia. | dengue is a serious public health problem in malaysia. the aim of this study was to compare the vertical infestation of aedes population in 2 apartments in kuala lumpur with different status of dengue incidence (i.e., high-dengue-incidence area and area with no reported dengue cases). the study was also conducted to assess the relationship between environmental factors such as rainfall, temperature, and humidity and aedes population that may influence aedes infestation. surveillance with a mosqu ... | 2013 | 24551965 |
| the risk of aedes aegypti breeding and premises condition in south mexico. | a recent innovation instrumented for the dengue prevention and control program in mexico is the use of the premises condition index (pci) as an indicator of risk for the vector aedes aegypti infestation in dengue-endemic localities of mexico. this paper addresses whether further improvements for the dengue control program could be made if the prevalence and productivity of ae. aegypti populations could be reliably predicted using pci at the household level, as well as medium-sized neighborhoods. ... | 2013 | 24551966 |
| an improved trap to capture adult container-inhabiting mosquitoes. | although dengue viruses are thought to be transmitted by aedes aegypti in puerto rico, aedes mediovittatus, the caribbean tree hole mosquito, is also a potential vector. this species is native to the greater antilles and has been shown to be a competent vector of dengue viruses in the laboratory. consequently, it has been suggested that ae. mediovittatus could be acting as a secondary vector or virus reservoir. this study was part of an ongoing investigation into this, and it aimed to determine ... | 0 | 24551969 |
| chitosan/sirna nanoparticle targeting demonstrates a requirement for single-minded during larval and pupal olfactory system development of the vector mosquito aedes aegypti. | essentially nothing is known about the genetic regulation of olfactory system development in vector mosquitoes, which use olfactory cues to detect blood meal hosts. studies in drosophila melanogaster have identified a regulatory matrix of transcription factors that controls pupal/adult odorant receptor (or) gene expression in olfactory receptor neurons (orns). however, it is unclear if transcription factors that function in the d. melanogaster regulatory matrix are required for or expression in ... | 2014 | 24552425 |
| larvicidal potential of silver nanoparticles synthesized from leucas aspera leaf extracts against dengue vector aedes aegypti. | vector-borne diseases caused by mosquitoes are one of the major economic and health problems in many countries. the aedes aegypti mosquito is a vector of several diseases in humans like yellow fever and dengue. vector control methods involving the use of chemical insecticides are becoming less effective due to development of insecticides resistance, biological magnification of toxic substances through the food chain, and adverse effects on environmental quality and non-target organisms including ... | 2014 | 24553980 |
| ecotoxicity and environmental risk assessment of larvicides used in the control of aedes aegypti to daphnia magna (crustacea, cladocera). | dengue transmitted by mosquitoes of the genus aedes, species aegypti, is a major public health concern in brazil. the chemical control of the mosquito larvae has been performed with the larvicide temephos since 1967. however, vector resistance was reported to temephos in several brazilian states, and the ministry of health ordered the replacement of this larvicide by diflubenzuron (dfb), an inhibitor of chitin synthesis. both insecticides are diluted in water with larvae and are able to reach aq ... | 2014 | 24555645 |
| an unusual cause of acute abdominal pain in dengue fever. | dengue fever is an acute febrile viral disease caused by the bite of aedes aegypti mosquito. it is a major health problem especially in tropical and subtropical areas including south east asia and pakistan. in the past few years, dengue fever has been endemic in northern punjab. physicians managing dengue fever come across varied and uncommon complications of dengue fever. we report a case of dengue fever that developed severe right upper quadrant abdominal pain and induration after extreme retc ... | 2014 | 24560393 |
| rapid evolution of reduced receptivity to interspecific mating in the dengue vector aedes aegypti in response to satyrization by invasive aedes albopictus. | in this paper we examine the effect of reproductive interference on the dynamics of two mosquito vectors of public health concern and add to the growing literature on the strength and speed with which interspecific reproductive interference may drive evolution. recent evidence supports a role for asymmetric reproductive interference, or satyrization, in competitive displacements of aedes aegypti by aedes albopictus. however, populations of a. aegypti sympatric with a. albopictus in nature evolve ... | 0 | 24563572 |
| urban epidemic of dengue virus serotype 3 infection, senegal, 2009. | an urban epidemic of dengue in senegal during 2009 affected 196 persons and included 5 cases of dengue hemorrhagic fever and 1 fatal case of dengue shock syndrome. dengue virus serotype 3 was identified from all patients, and aedes aegypti mosquitoes were identified as the primary vector of the virus. | 0 | 24572297 |
| a new tent trap for monitoring the daily activity of aedes aegypti and aedes albopictus. | in this study, we designed a new tent trap; the biodivector (bdv) tent trap, consisting of two rectangular tents that use human bait without endangering the technical personnel. the daily activity pattern of aedes aegypti and aedes albopictus in intra, peri, and extradomiciliary sites was studied in an endemic area of dengue in southern mexico by using the bdv tent trap. totals of 3,128 individuals of ae. aegypti and 833 ae. albopictus were captured. more ae. aegypti males than females were caug ... | 2013 | 24581356 |
| the genetics of chemoreception in the labella and tarsi of aedes aegypti. | the yellow-fever mosquito aedes aegypti is a major vector of human diseases, such as dengue, yellow fever, chikungunya and west nile viruses. chemoreceptor organs on the labella and tarsi are involved in human host evaluation and thus serve as potential foci for the disruption of blood feeding behavior. in addition to host detection, these contact chemoreceptors mediate feeding, oviposition and conspecific recognition; however, the molecular landscape of chemoreception in these tissues remains m ... | 2014 | 24582661 |
| limited dengue virus replication in field-collected aedes aegypti mosquitoes infected with wolbachia. | dengue is one of the most widespread mosquito-borne diseases in the world. the causative agent, dengue virus (denv), is primarily transmitted by the mosquito aedes aegypti, a species that has proved difficult to control using conventional methods. the discovery that a. aegypti transinfected with the wmel strain of wolbachia showed limited denv replication led to trial field releases of these mosquitoes in cairns, australia as a biocontrol strategy for the virus. | 2014 | 24587459 |
| comparative analysis of response to selection with three insecticides in the dengue mosquito aedes aegypti using mrna sequencing. | mosquito control programmes using chemical insecticides are increasingly threatened by the development of resistance. such resistance can be the consequence of changes in proteins targeted by insecticides (target site mediated resistance), increased insecticide biodegradation (metabolic resistance), altered transport, sequestration or other mechanisms. as opposed to target site resistance, other mechanisms are far from being fully understood. indeed, insecticide selection often affects a large n ... | 2014 | 24593293 |
| socially structured human movement shapes dengue transmission despite the diffusive effect of mosquito dispersal. | for sexually and directly transmitted infectious diseases, social connections influence transmission because they determine contact between individuals. for pathogens that are indirectly transmitted by arthropod vectors, the movement of the vectors is thought to diminish the role of social connections. results from a recent study of mosquito-borne dengue virus (denv), however, indicate that human movement alone can explain significant spatial variation in urban transmission rates. because moveme ... | 2014 | 24593919 |
| atypical manifestations of dengue fever (df) - where do we stand today? | dengue fever (df) is transmitted by aedes aegypti mosquitoes. with growing population, rapid urbanization and lack of appropriate sanitary measures, proliferation of mosquitoes and subsequent dengue infections have increased rampantly with an estimated 30-fold increase in incidence over last five decades. with rising disease burden, atypical manifestations have increased as well, which are missed most often due to lack of awareness. our aim was to look for the atypical manifestations of dengue f ... | 2013 | 24596727 |
| vectorial capacity of aedes aegypti: effects of temperature and implications for global dengue epidemic potential. | dengue is a mosquito-borne viral disease that occurs mainly in the tropics and subtropics but has a high potential to spread to new areas. dengue infections are climate sensitive, so it is important to better understand how changing climate factors affect the potential for geographic spread and future dengue epidemics. vectorial capacity (vc) describes a vector's propensity to transmit dengue taking into account human, virus, and vector interactions. vc is highly temperature dependent, but most ... | 2014 | 24603439 |
| development of the gravid aedes trap for the capture of adult female container-exploiting mosquitoes (diptera: culicidae). | monitoring dengue vector control by sampling adult aedes aegypti (l.) recently has been used to replace both larval and pupal surveys. we have developed and evaluated the gravid aedes trap (gat) through a sequential behavioral study. the gat does not require electricity to function, and trapped mosquitoes are identified easily during trap inspections. the gat concept relies on visual and olfactory cues to lure gravid ae. aegypti and an insecticide to kill trapped mosquitoes. gravid mosquitoes ar ... | 2014 | 24605470 |
| field validation of the gravid aedes trap (gat) for collection of aedes aegypti (diptera: culicidae). | current surveillance methods for adult aedes aegypti (l.) are expensive, require electrical power (e.g., the bg-sentinel trap, bgs), are labor intensive (aspirators), or require difficult to use and costly adhesives (sticky ovitraps). field trials were conducted in cairns (australia) to compare the efficacy of the newly designed gravid aedes trap (gat) against existing sticky ovitraps (mosquitrap and double sticky ovitrap) and the bgs. latin square design trials confirmed that alarge gat using a ... | 2014 | 24605471 |
| immuno-chromatographic wicking assay for the rapid detection of dengue viral antigens in mosquitoes (diptera: culicidae). | there is a threat for dengue virus (denv) reemergence in many regions of the world, particularly in areas where the denv vectors, aedes aegypti (l.) and aedes albopictus (skuse), are readily available. however, there are currently no accurate and reliable diagnostic methods to provide critical, real-time information for early detection of denv within the vector populations to implement appropriate vector control and personal protective measures. in this article, we report the ability of an immun ... | 2014 | 24605472 |
| the maxillary palp of aedes aegypti, a model of multisensory integration. | female yellow-fever mosquitoes, aedes aegypti, are obligate blood-feeders and vectors of the pathogens that cause dengue fever, yellow fever and chikungunya. this feeding behavior concludes a series of multisensory events guiding the mosquito to its host from a distance. the antennae and maxillary palps play a major role in host detection and other sensory-mediated behaviors. compared to the antennae, the maxillary palps are a relatively simple organ and thus an attractive model for exploration ... | 2014 | 24613607 |
| vertical transmission of dengue virus in aedes aegypti collected in puerto iguazú, misiones, argentina. | a finding of vertical transmission of the den 3 virus in male specimens of aedes aegypti, collected in the 2009 fall-winter period, in puerto iguazú city, misiones, argentina, using the rt-pcr technique in a 15-specimen pool is reported. this result is analyzed within the context of the epidemiological situation of argentina's northeast border. | 0 | 24626420 |
| [design and evaluation of a ovitrap for monitoring and control of aedes aegypti, dengue fever vector]. | to design and evaluate in field conditions an ovitrap with chemical attractants and a population regulator for the monitoring and control of dengue vectors. | 2014 | 24626622 |
| temporal genetic structure of major dengue vector aedes aegypti from manaus, amazonas, brazil. | in recent years, high levels of aedes aegypti infestation and several dengue outbreaks with fatal outcome cases have been reported in manaus, state of amazonas, brazil. this situation made it important to understand the genetic structure and gene flow patterns among the populations of this vector in manaus, vital pieces of information for their management and development of new control strategies. in this study, we used nine microsatellite loci to examine the effect of seasonality on the genetic ... | 2014 | 24631342 |
| green synthesis of silver nanoparticles using delphinium denudatum root extract exhibits antibacterial and mosquito larvicidal activities. | green synthesis of silver nanoparticles (agnps) using aqueous root extract of delphinium denudatum (dd) by reduction of ag(+) ions from silver nitrate solution has been investigated. the synthesized ddagnps were characterized by using uv-vis spectroscopy, x-ray diffraction (xrd), field emission scanning electron microscope (fesem) and fourier transform infrared spectroscopy (ftir). the prepared ddagnps showed maximum absorbance at 416nm and particles were polydispersed in nature, spherical in sh ... | 2014 | 24632157 |
| human igg antibody response to aedes aegypti nterm-34 kda salivary peptide as an indicator to identify areas at high risk for dengue transmission: a retrospective study in urban settings of vientiane city, lao pdr. | using human igg antibody response to the aedes nterm-34 kda salivary peptide as an indicator of human exposure to aedes bites in surveying exposed populations from areas at risk of dengue virus (denv) transmission in urban settings of vientiane city, lao pdr. | 2014 | 24641205 |
| macroclimate determines the global range limit of aedes aegypti. | aedes aegypti is the main vector of dengue and a number of other diseases worldwide. because of the domestic nature of this mosquito, the relative importance of macroclimate in shaping its distribution has been a controversial issue. we have captured here the worldwide macroclimatic conditions occupied by a. aegypti in the last century. we assessed the ability of this information to predict the species' observed distribution using supra-continental spatially-uncorrelated data. we further project ... | 2014 | 24643859 |
| identification of carboxylesterase genes implicated in temephos resistance in the dengue vector aedes aegypti. | thailand is currently experiencing one of its worst dengue outbreaks in decades. as in most countries where this disease is endemic, dengue control in thailand is largely reliant on the use of insecticides targeting both immature and adult stages of the aedes mosquito, with the organophosphate insecticide, temephos, being the insecticide of choice for attacking the mosquito larvae. resistance to temephos was first detected in aedes aegypti larvae in thailand approximately 25 years ago but the me ... | 2014 | 24651719 |
| [status of insecticide susceptibility of public health use in natural populations of aedes aegypti (diptera: culicidae) of casanare, colombia]. | physiological resistance of aedes aegypti is a major threat to effective control programs in the transmission of dengue virus. | 2014 | 24652181 |
| [determining the status of susceptibility to organophosphate, carbamate and pyrethroids insecticides in populations of aedes aegypti linneaus, 1762 (diptera: culicidae) in panamá]. | we studied the susceptibility to organophosphate, carbamate and pyrethroid insecticides of aedes aegypti from different regions of high transmission risk for dengue in panama. | 2013 | 24652251 |
| [genetic differences between populations of aedes aegypti from municipalities in northern colombia, with high and low dengue incidence]. | aedes aegypti is the principal vector of dengue in urban areas. despite its epidemiological importance, the genetic variability of colombian populations of this species is unknown. | 2013 | 24652253 |
| differential susceptibility of two field aedes aegypti populations to a low infectious dose of dengue virus. | the infectious dose required to infect mosquito vectors when they take a blood meal from a viremic person is a critical parameter underlying the probability of dengue virus (denv) transmission. because experimental vector competence studies typically examine the proportion of mosquitoes that become infected at intermediate or high denv infectious doses in the blood meal, the minimum blood meal titer required to infect mosquitoes is poorly documented. understanding the factors influencing the low ... | 2014 | 24664142 |
| larvicidal potential of wild mustard (cleome viscosa) and gokhru (tribulus terrestris) against mosquito vectors in the semi-arid region of western rajasthan. | cleome viscosa l. (family: capparaceae) commonly known as tickweed or wild mustard and tribulus terrestris l. (family: zygophyllaceae) commonly known as gokhru, growing wildly in the desert areas in the monsoon and post monsoon season, are of great medicinal importance. comparative larvicidal efficacy of the extracts from seeds of c. viscosa and fruits and leaves of t. terrestris was evaluated against 3rd or early 4th stage larvae of anopheles stephensi (liston), aedes aegypti (linnaeus) and cul ... | 2014 | 24665757 |
| high level of vector competence of aedes aegypti and aedes albopictus from ten american countries as a crucial factor in the spread of chikungunya virus. | chikungunya virus (chikv) causes a major public health problem. in 2004, chikv began an unprecedented global expansion and has been responsible for epidemics in africa, asia, islands in the indian ocean region, and surprisingly, in temperate regions, such as europe. intriguingly, no local transmission of chikungunya virus (chikv) had been reported in the americas until recently, despite the presence of vectors and annually reported imported cases. here, we assessed the vector competence of 35 am ... | 2014 | 24672026 |
| undesirable consequences of insecticide resistance following aedes aegypti control activities due to a dengue outbreak. | during a dengue outbreak with co-circulation of denv-1 and -2 in the city of boa vista, one patient was diagnosed with denv-4, a serotype supposed absent from brazil for almost 30 years. the re-emergence of denv-4 triggered the intensification of mechanical and chemical aedes aegypti control activities in order to reduce vector density and avoid denv-4 dissemination throughout the country. | 2014 | 24676277 |
| dengue transmission model by means of viremic adult immuno-competent mouse. | dengue virus infection manifests in three distinct forms in humans: dengue fever, dengue hemorrhagic fever, and dengue shock syndrome. infection with the virus is a fatal disease; no vaccine is available and prevention depends on interruption of the chain of transmission. the study of dengue viral transmission by mosquitoes is hindered due to the lack of an affordable animal model. in general, immuno-competent mice are used as a simple and inexpensive animal model, but mice are not susceptible t ... | 2014 | 24685121 |
| criteria for identifying and evaluating candidate sites for open-field trials of genetically engineered mosquitoes. | recent laboratory successes in the development of genetically engineered mosquitoes for controlling pathogen transmission have fostered the need for standardized procedures for advancing the technical achievements to practical tools. it is incumbent in many cases for the same scientists doing the in-laboratory discovery research to also take on the initial challenges of developing the pathway that will move the technologies to the field. one of these challenges is having a set of criteria for se ... | 2014 | 24689963 |
| preliminary evaluation on the efficiency of the kit platelia dengue ns1 ag-elisa to detect dengue virus in dried aedes aegypti: a potential tool to improve dengue surveillance. | surveillance is a critical component of any dengue prevention and control programme. herein, we investigate the efficiency of the commercial kit platelia dengue ns1 ag-elisa to detect dengue virus (denv) antigens in aedes aegypti mosquitoes infected under laboratory conditions. | 2014 | 24690324 |
| novel genetic and molecular tools for the investigation and control of dengue virus transmission by mosquitoes. | aedes aegypti is the principal vector of dengue virus (denv) throughout the tropical world. this anthropophilic mosquito species needs to be persistently infected with denv before it can transmit the virus through its saliva to a new vertebrate host. in the mosquito, denv is confronted with several innate immune pathways, among which rna interference is considered the most important. the ae. aegypti genome project opened the doors for advanced molecular studies on pathogen-vector interactions in ... | 0 | 24693489 |
| homodimerization propensity of the intrinsically disordered n-terminal domain of ultraspiracle from aedes aegypti. | the mosquito aedes aegypti is the principal vector of dengue, one of the most devastating arthropod-borne viral infections in humans. the isoform specific a/b region, called the n-terminal domain (ntd), is hypervariable in sequence and length and is poorly conserved within the ultraspiracle (usp) family. the usp protein together with ecdysteroid receptor (ecr) forms a heterodimeric complex. up until now, there has been little data on the molecular properties of the isolated usp-ntd. here, we des ... | 2014 | 24704038 |
| design, synthesis, acetylcholinesterase inhibition and larvicidal activity of girgensohnine analogs on aedes aegypti, vector of dengue fever. | girgensohnine alkaloid was used as a natural model in the design and generation of new alkaloid-like α-aminonitrile series that was completed by the use of ssa-catalyzed strecker reaction between commercial and inexpensive substituted benzaldehydes, piperidine (pyrrolidine, morpholine and n-methylpiperazine) and acetone cyanohydrin. calculated admetox parameters of the designed analogs revealed their good pharmacokinetic profiles indicating lipophilic characteristics. in vitro ache enzyme test s ... | 2014 | 24704612 |
| burchellin: study of bioactivity against aedes aegypti. | the dengue mosquito aedes aegypti linnaeus, 1762 is a widespread insect pest of serious medical importance. since no effective vaccine is available for treating dengue, the eradication or control of the main mosquito vector is regarded as essential. since conventional insecticides have limited success, plants may be an alternative source of larvicidal agents, since they contain a rich source of bioactive chemicals. the aim of this study was to evaluate the larvicidal activity of the neolignan bu ... | 2014 | 24713267 |
| [evaluation of personal protective equipment used by malathion sprayers in dengue control in são paulo, brazil]. | malathion insecticide in vegetable oil is used to control aedes aegypti and is applied by spraying, which requires the use of personal protective equipment (ppe). the current study assessed the capacity of ppe suits to retain malathion. the study monitored field spraying in são paulo, brazil. before each spraying, feminine sanitary napkins were placed under and upon the ppe suit in the chest, back, and forearms. after spraying, the sanitary napkins were removed, labeled, and submitted to extract ... | 2014 | 24714946 |
| a study on container breeding mosquitoes with special reference to aedes (stegomyia) aegypti and aedes albopictus in thiruvananthapuram district, india. | the district of thiruvananthapuram reports the maximum number of cases of dengue in the state of kerala. to determine the larval diversity, density and breeding site preferences of aedes mosquitoes, during pre-monsoon and monsoon periods in urban and rural areas of thiruvananthapuram district. | 2014 | 24717199 |