Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| effect of tetracycline in hypotensive patients with non-vibrio cholera-like disease in calcutta. | 1965 | 5882326 | |
| [a method for the determination and study of polysaccharides in vibrio cholerae]. | 1965 | 5885701 | |
| hemolysin-destructive factor of vibrio cholerae (vibrio comma). | 1966 | 5903110 | |
| antibody formation against vibrio cholerae by mesenteric lymph node cell transfer. | 1966 | 5917020 | |
| preparation of the vascular permeability factor of vibrio cholerae. | 1966 | 5922548 | |
| cholera in the perspective of 1966. | cholera is a disease state caused by the vibrio cholerae. the vibrios remain in the gut lumen, and the disease is atypically afebrile. the main symptom is a profuse isotonic diarrhea of rice-water character with an output rate of as much as 1 liter/hour. early signs in the untreated patient are skeletal muscle cramps (presumably due to electrolyte loss) and vomiting. mortality rate in untreated cases may be as high as 80%, and in treated cases, 20%. the u.s. navy method of treating chlera h ... | 1966 | 5923097 |
| laboratory vibrio cholerae infection in the united states. | 1966 | 5952839 | |
| incorporation of p-32 activity in different chemical fractions of vibrio cholerae. | 1966 | 5959890 | |
| some ultrastructural aspects of vibrio cholerae. | 1966 | 5961046 | |
| [a new medium for the isolation of vibrio cholera]. | 1966 | 5963392 | |
| variation in a strain of classical vibrio cholerae. | 1966 | 5970132 | |
| effect of nutrients on the antigenic structure of vibrio cholerae. | 1966 | 5976561 | |
| effect of toluene on vibrio cholerae. | 1966 | 5981465 | |
| formation of protoplasts from vibrio cholerae. | 1966 | 6003986 | |
| [frequency of phage-resistant mutations and effect of the bacteriophage on the formation of resistant forms of vibrio cholera]. | 1966 | 6005460 | |
| culture of serum-induced spheroplasts from vibrio cholerae. | spheroplasts of vibrio cholerae types inaba, hikojima, and ogawa were produced in serum. an excess of lysozyme was added to expedite transformation, and cacl(2) was used as the stabilizing agent. at the optimal time for each strain, when less than 1% classical rod forms were observed microscopically, samples were plated on both conventional and modified l-form media. no growth occurred on conventional media; l-form type colonies appeared on l-form media after 2 to 6 days of incubation. l-form co ... | 1967 | 6025453 |
| method for determining antineuraminidase activity. | a test was developed to screen drugs for antineuraminidase (influenza sialidase) activity in vitro. neuraminidase prepared from vibrio cholerae was added to a substrate containing ganglioside, prepared from calf brain. sialic acid is a split product in the reaction. the presence of sialic acid was detected colorimetrically by use of warren's thiobarbituric acid assay after drugs had been added to inhibit the action of neuraminidase on the calf brain substrate. | 1967 | 6029825 |
| studies in immunochemistry of vibrio cholerae. vii. action of enzymes on the antigens. | 1967 | 6056277 | |
| spot plate method for the detection of hemolysin and hemodigestive enzyme of vibrio cholerae. | 1967 | 6064849 | |
| [atypical forms of vibrio cholerae]. | 1983 | 6086048 | |
| transposon-mediated mutagenesis and recombination in vibrio cholerae. | an efficient method for introducing transposons into the vibrio cholerae chromosome or the p plasmid was developed by using f'tslac+ plasmids from escherichia coli as suicide delivery vehicles. hybrid p::tn1, tn5 and p::tn1, tn10 plasmids containing tn5 or tn10 in either of the two possible orientations were constructed. during conjugation, these hybrid plasmids mediated oriented transfer of markers from the sites of insertion of homologous transposons in the donor chromosome. the collection of ... | 1984 | 6086528 |
| [use of r plasmids for isolating vibrio cholerae donor strains]. | vibrio cholerae and vibrio eltor donor strains were obtained using r plasmids rp1ts, prp19.6, pth10 and pns10 which carry is or tn elements. resulting from integration of the plasmids into cholera vibrio chromosome, two types of donors were constructed: those resembling escherichia coli hfr's and the strains analogous to f+ or f' donors. the order of some chromosome markers were determined in crosses between the donors obtained and v. cholerae recipient strains. | 1984 | 6088363 |
| [lymphatic diseases specific to the tropics (burkitt's lymphoma, tropical splenomegaly and mediterranean lymphoma)]. | certain lymphoproliferative disorders (burkitt's lymphoma, tropical splenomegaly, and mediterranean lymphoma) are more frequently observed in the tropical or subtropical areas than in other parts of the world. the polymicrobial exposure of human beings in those areas to viral, bacterial and protozoal infections led to the assumption of a specific connection between these conditions and the lymphoproliferative disease. some evidence has accumulated that the epstein-barr virus might be an oncogeni ... | 1984 | 6089444 |
| vibrio cholerae enterotoxin genes: nucleotide sequence analysis of dna encoding adp-ribosyltransferase. | the nucleotide sequence of the dna encoding the adp-ribosyltransferase (a1) fragment of cholera enterotoxin was determined. a putative precursor of the a1 peptide contains an 18-amino acid leader peptide, and the mature a1 peptide contains 194 amino acids. the primary structure of the a1 fragment from cholera enterotoxin is more related to that from a human enterotoxigenic escherichia coli than to that from a porcine enterotoxigenic e. coli. | 1984 | 6090390 |
| molecular cloning of the hemolysin determinant from vibrio cholerae el tor. | vibrio cholerae el tor rv79 is phenotypically nonhemolytic; however, strongly hemolytic convertants are occasionally observed on blood agar plates. we have cloned dna sequences corresponding to the hemolysin determinant from rv79 (hly+) in the lambda l47.1 and pbr322 vectors. a 2.3-kilobase fragment of v. cholerae dna was found to be necessary for hemolytic activity. this cloned dna sequence was used as a probe in southern blot hybridization analysis of chromosomal restriction digests of a varie ... | 1984 | 6090415 |
| adenylate cyclase activity in toxigenic and nontoxigenic strains of vibrio cholerae: effect of different carbohydrates. | 1983 | 6094650 | |
| [cholera research 100 years after its discovery--current topics]. | 1984 | 6094878 | |
| serology and plasmid carriage in vibrio cholerae. | vibrio cholerae strains of the 01 serovar, isolated from both clinical and environmental sources, had a much lower frequency of plasmid carriage (2/112 = 2%) than clinical and environmental non-01 serovar isolates (46/187 = 25%). the cryptic plasmids found in non-01 strains were all of low molecular weight and were shown by hybridization analysis to consist of two unrelated subgroups. each subgroup was observed to be present in strains isolated from both clinical and environmental sources. one 0 ... | 1984 | 6095986 |
| [h-nmr spectroscopy. specificity of microbial sialidases against complex substrates]. | the specificities of one viral and five bacterial sialidases were investigated by 1h-nmr-spectroscopy with substrates or substrate mixtures containing two sialic acid residues of different linkage types. this technique allows - in contrast to the methods used before - the simultaneous determination of the rates of hydrolysis of both neuac linkages in a single experiment. the substrate specificities of the enzymes are discussed on the basis of the relation of the rate constants k/k'. the data obt ... | 1984 | 6096253 |
| [acute gastroenteritis and breast feeding in gabon. preliminary results]. | 76 diarrheic infants (from 15 days to 2 years) had a stool examination for rotavirus (elisa method) and a stool culture and were classified according to breast feeding or not. this study was performed in a semi-urban region (haut-ogooué, gabon). the preliminary results suggest a protection by breast feeding against rotavirus and enteropathogenic bacteria, rapid elimination of diarrheic agents may be facilitated by human milk. | 1984 | 6097788 |
| cloning of the structural gene (hly) for the haemolysin of vibrio cholerae el tor strain 017. | we have cloned the dna encoding the haemolysin of vibrio cholerae el tor strain 017 into the plasmid vector pbr322. the resultant plasmid, ppm431, has a 6.2-kb psti dna insert which leads to the production of the haemolysin in escherichia coli k-12. deletion analysis and transposon mutagenesis have allowed us to localize several regions affecting haemolysin production. a number of these mutants have been analysed in e. coli k-12 minicells. three proteins have been identified: a, 80 kdal; b, 71 k ... | 1984 | 6098527 |
| role of rotavirus as the cause of acute paediatric diarrhoea in calcutta. | of the 245 acute paediatric diarrhoea cases admitted to the infectious diseases hospital, calcutta between july, 1979 and june, 1981, rotavirus was detected in the faeces of 55 (22.4%) patients either as the sole aetiological agent or in association with other enteropathogens. children aged six months to two years were most commonly infected. the virus was detected throughout the year with higher incidence during the winter months of both years. the frequency of detection of major enteropathogen ... | 1984 | 6099923 |
| plasmid-encoded multiple antibiotic resistance in vibrio cholerae el tor from bangladesh. | 1980 | 6104055 | |
| enterotoxigenic escherichia coli: identification and characterization. | 1980 | 6106031 | |
| binding of intraluminal toxin in cholera: trial of gm1 ganglioside charcoal. | a study was undertaken to investigate whether toxin produced in the gut lumen contributes significantly to clinical illness and whether binding such toxin by gm1 ganglioside adsorbed onto charcoal could alter the clinical course of disease. 46 patients with severe cholera receiving standard intravenous therapy were randomly assigned to one of three groups: gm1 ganglioside-charcoal (16), charcoal alone (16), or water (14). the results demonstrated that patients were given sufficient gm1 gangliosi ... | 1980 | 6107548 |
| imported cholera detected by routine stool culture. | 1980 | 6107702 | |
| recurrence of pelecypod-associated cholera in sardinia. | from oct. 30 to nov. 7, 1979, 10 people in the sardinian province of cagliari had onset of bacteriologically confirmed cholera. two symptom-free excretors of vibrio cholerae o:1 were detected in household contacts of the patients. there were no deaths. all but 1 of the 12 people with v. cholerae o:1 infection gave a history of recent consumption of marine bivalves known locally as arselle (pelecypods). triplicate matched neighbourhood controls for each of the first 7 cases identified were also i ... | 1980 | 6107735 |
| [mechanism of action of cholera toxin (author's transl)]. | 1980 | 6113582 | |
| breast milk and infection. | there were several problems with the editorial on breastmilk and infection appearing in the may 30 lancet. of the antiinfective substances in human milk, lysozyme was omitted, as were the bifidus factor, the antistaphylococcus factor, antitoxins for neutralizing vibrio cholerae and escherichia coli, lactoperoxidase, and volatile fatty acids. low ph and the exclusive specific bifidus bowel flora are all components of the same interacting antiinfective screen, as are macrophages and lymphocytes. ... | 1981 | 6115183 |
| cloned cholera enterotoxin genes in study and prevention of cholera. | 1981 | 6118594 | |
| nad metabolism in vibrio cholerae. | extracts of vibrio cholerae were assayed for various enzymatic activities associated with pyridine nucleotide cycle metabolism. the activities measured include nad glycohydrolase, nicotinamide deamidase, nicotinamide mononucleotide deamidase, and nicotinic acid phosphoribosyltransferase. the results obtained demonstrate the existence in v. cholerae of the five-membered pyridine nucleotide cycle and the potential for a four-membered pyridine nucleotide cycle. the data presented also suggest that ... | 1982 | 6119307 |
| vibrio cholerae el tor acquires plasmid-encoded resistance to gentamicin. | 1982 | 6119431 | |
| cholera toxin. | 1982 | 6121589 | |
| cholera and estuarine salinity in calcutta and london. | 1982 | 6122976 | |
| expression of cloned cholera enterotoxin gene in escherichia coli and possibilities of vaccine development. | 1982 | 6122988 | |
| rice-powder electrolyte solution as oral-therapy in diarrhoea due to vibrio cholerae and escherichia coli. | 124 patients with acute diarrhoea due to vibrio cholerae or escherichia coli were treated with either the standard sucrose-electrolyte solution or a cereal-based electrolyte solution, containing 30 g rice powder per litre and electrolytes as recommended by the world health organisation. the treatments were compared by measuring the rate of purging, change in body weight, serum specific gravity, urine output, and post-hydrolysis sugar content in the stool. the proportions of successfully treated ... | 1982 | 6123635 |
| enteropathogenicity: recent developments. | recent studies have added important new information to our understanding of the pathogenesis and ethiology of diarrheal disease. vibrio cholerae produces a heat-labile enterotoxin, affecting cyclic amp. a very similar heat-labile enterotoxin is produced also by certain strains of escherichia coli, as well as by citrobacter, klebsiella, and aeromonas. e. coli may also produce a heat-stable enterotoxin, stimulating guanylate cyclase activity. in order to produce the pathologic effects, e. coli fir ... | 1982 | 6126611 |
| simple test for serological diagnosis of infection with enterotoxigenic escherichia coli. | 1983 | 6129433 | |
| enteropathogenic agents in children with diarrhoea in rural zaire. | a systematic study of enteropathogenic agents in the stools of children was carried out in a rural area of kivu province in zaire in june, 1979. 84 inpatients and 271 outpatients with diarrhoea were investigated together with 117 inpatient and 203 outpatient controls without diarrhoea. campylobacter jejuni was the most frequently recovered pathogen in both inpatients (24%) and outpatients (13.7%). enterotoxigenic escherichia coli was the next most common among children presenting as outpatients ... | 1983 | 6131221 |
| classical vibrio cholerae biotype displaces el tor in bangladesh. | the el tor biotype of vibrio cholerae caused all endemic and epidemic cholera in bangladesh from 1973 until sept. 3, 1982, when the first classical strain was isolated from a patient in matlab. since then the number of isolations of the classical biotype has increased very rapidly and spread to other districts, replacing the el tor biotype as the main epidemic strain. the classical strains isolated in the 1982 outbreak were indistinguishable by the standard tests from those isolated a decade ago ... | 1983 | 6132141 |
| the question of classical cholera. | 1983 | 6132212 | |
| a new cholera toxin. | 1983 | 6134125 | |
| toxins in environmental vibrio cholerae. | 1983 | 6135049 | |
| toxigenic vibrio cholerae o1 strain from mexico identical to united states isolates. | 1983 | 6137722 | |
| on the specificity of sialidase. synthesis and properties of n5-acetyl-beta-d-neuraminoylpeptides - acneu-gly-oh, acneu-glu-oh, acneu-phe-oh - and the corresponding alpha-ketosides. | by means of the mixed anhydride procedure the benzyl alpha-ketoside of n5-acetyl-d-neuraminic acid was linked to l-glycine, l-glutamic acid and l-phenylalanine. hydrogenolytic cleavage of the benzyl group resulted in the corresponding free n5-acetyl-beta-d-neuraminoylpeptides. this new class of compounds is no substrate for vibrio cholerae sialidase. the enzyme does not split the benzyl alpha-ketosides of n5-acetyl-d-neuraminoylpeptides nor is its activity inhibited by these compounds. the resul ... | 1983 | 6139332 |
| environmental and human isolates of vibrio cholerae and vibrio parahaemolyticus produce a shigella dysenteriae 1 (shiga)-like cytotoxin. | some strains of vibrio parahaemolyticus, vibrio cholerae, and non-o1 v cholerae produce a bacterial-cell-associated, heat-stable material that is cytotoxic for hela cells. cytotoxicity is completely neutralised by antibody to purified shigella dysenteriae 1 (shiga) toxin but not by antibody to purified cholera toxin. | 1984 | 6140426 |
| vibrio cholerae non-o1 isolated from five people with diarrhoea in lima. | 1984 | 6141352 | |
| foodborne transmission of cholera in micronesian households. | during a cholera epidemic in truk (micronesia), in a survey of 1 village, transmission of vibrio cholerae o1 in the 28 households with illness appeared to be through food contaminated in the home. households in which the index case was a foodhandler had significantly higher attack rates than households in which the index case was not a foodhandler. members of households with illness were significantly more likely to become ill if they had eaten food prepared by a foodhandler who had recently bee ... | 1984 | 6141390 |
| vibrio cholerae in south america. | 1984 | 6142324 | |
| effect of lodoxamide on the secretory response induced by escherichia coli and vibrio cholerae enterotoxins in infant mice. | the effect of lodoxamide tromethamine, a calcium antagonist, on intestinal fluid accumulation induced by escherichia coli heat-stable (st) and vibrio cholerae (ct) enterotoxins in infant mice was investigated. the simultaneous administration of lodoxamide with st or ct enterotoxin resulted in a significant (p less than 0.01) inhibition of the intestinal fluid response. a minimum concentration of 10(-7) or 10(-8)m lodoxamide caused an inhibition (p less than 0.01) of the st- or ct-mediated fluid ... | 1984 | 6143729 |
| hospital outbreaks of cholera transmitted through close person-to-person contact. | three hospital outbreaks of cholera which started in a children's infectious diseases ward in dar es salaam in 1977/78, 1981, and 1983 were controlled by bacteriological screening and isolation of infected patients, administration of antibacterial chemoprophylaxis to all at-risk patients and their accompanying relatives, and by reducing overcrowding. the outbreaks in 1981 and 1983 were caused by two distinct multiply antibiotic resistant e1 tor vibrio cholerae o1 strains. in these three outbreak ... | 1984 | 6146017 |
| effect of intravenous somatostatin on stool output in diarrhea due to vibrio cholerae. | somatostatin has been shown to inhibit intestinal secretion induced by a variety of secretagogues. the ability of somatostatin to reduce stool output in patients with cholera was therefore investigated in a double-blind randomized controlled trial. twenty-two patients with severe purging due to infection with vibrio cholerae (less than or equal to 12.5 ml/kg x h) received either somatostatin at a dose of 250 micrograms/h in saline (n = 12) or placebo (n = 10). the study drug was given for 12 h f ... | 1984 | 6147293 |
| alum potash in water to prevent cholera. | 1984 | 6149407 | |
| [bacterial diarrhoea: diarrhoea caused by enterotoxins]. | 1984 | 6150126 | |
| cytotoxin production by members of genus vibrio. | 1984 | 6150265 | |
| enteropathogenicity of klebsiella pneumoniae strains isolated from stools of diarrhoeal patients and other clinical specimens: an experimental study. | in recent years strains of klebsiella pneumoniae have been implicated as intestinal pathogen. sixty three strains isolated from faeces of children with or without diarrhoea and other specimens of extraintestinal infections were tested for their enteropathogenicity in biological models. thirty nine of them isolated from different sources caused accumulation of fluid in rabbit ileal loops comparable to that caused by toxigenic v. cholerae 569b. ten strains, however, required 1-3 serial passages in ... | 1984 | 6151766 |
| evidence for a functional role of gangliosides in synaptic transmission: studies on rat brain striatal slices. | the influence of neuraminidase from vibrio cholerae on evoked, extracellular potentials from rat brain striatal slices was tested. enzyme treatment abolished synaptic transmission within 90 min. biochemical analysis of the neuraminidase-treated slices has demonstrated a 10-fold increase in the amount of free sialic acid. the thin-layer chromatography of gangliosides extracted from enzyme-treated slices showed a decrease in the amount of polysialogangliosides (gd1a, gd1b, gt1b, gq1b) by 1.5-fold. ... | 1984 | 6152038 |
| characterization of the t antigen and t agglutinin in inbred rats. | treatment of rat erythrocytes with vibrio cholerae neuraminidase (vcn) exposed antigenic determinants on the cell surface membrane, and autologous rat serum contained antibodies which reacted with these determinants and with vcn-treated human erythrocytes. the antibodies were not present in sera of animals less than 8 weeks of age. human serum also contained antibodies which reacted with the vcn-treated rat erythrocytes. lectin isolated and purified from arachis hypogoea agglutinated vcn-treated ... | 1980 | 6155326 |
| clearance of normal and tumor-related thyroglobulin from the circulation of rats: role of the terminal sialic acid residues. | 1980 | 6155591 | |
| [antigenicity of a chemically induced neurogenic rat sarcoma (author's transl)]. | a neurogenic sarcoma was induced in the plexus brachialis of a male long-evans rat by administration of n-methyl-n-nitrosourea in the drinking water. the tumor was established in vitro and designated 76le-ns-369. cells from tissue culture grew as tumors when isografted in young rats. 76le-ns-369 cells did not react with antiserum directed against gliaspecific s-100 protein. we used the cultured cells as target cells, and found specific antibodies in the sera of tumor-bearing and immunized rats b ... | 1980 | 6155730 |
| metabolism of 4-o-methyl-n-acetylneuraminic acid a synthetic sialic acid. | 1. 4-o-methyl-n-acetylneuraminic acid shows a strong positive periodate-thiobarbiturate reaction. the mechanism of dye formation in this test for sialic acids is discussed in view of the studies already published. 2. an efficient preparation of a tritium-labelled 4-o-methyl-n-acetylneuraminic acid, with high specific radioactivity, by an oxymercuration-demercuration procedure is presented. 3. sialytransferase activities in microsomal fractions of equine liver using desialylated fetuin are studie ... | 1980 | 6156826 |
| isolation, characterization and implications of anti-tf (thomsen-friedenreich) agglutinins from different sources. | anti-tf agglutinins from peanut (arachis hypogaea) and from vertebrate sera of different species have been successfully isolated by affinity chromatography on acid-activated sepharose 4 b. the proteins were characterized by immunoelectrophoresis, polyacrylamide gel electrophoresis in the presence of sds and with respect to their carbohydrate binding specificities. anti-tf substances from sera showed one precipitin arc in immunoelectrophoresis, but quantitative immunoprecipitation revealed our hu ... | 1980 | 6157637 |
| [use of the aggregate hemagglutination method for determining cholera vibrio neuraminidase]. | the suitability of the aggregate hemagglutination test for neuraminidase determination in biological fluids has been evaluated. this test allows one to determine neuraminidase at a concentration of 2--4 mg/ml. the sensitivity of this test is more than 2 orders higher than that of gel diffusion technique and the thiobarbituric assay. the test has revealed that neuraminidase produced by vibrio cholerae is not immunologically related to other kinds of neuraminidase produced by corynebacterium dipht ... | 1980 | 6160701 |
| [characteristics of the heat-stable enterotoxin of nag vibrios]. | cell-free culture filtrate boiled for 15 minutes has been found to retain its biological activity in various experimental models used for the determination of the toxicogenicity of cholera vibrio filtrates. during gel filtration of the concentrated filrate o. nag vibrio, strain no. 9852, through sephadex g-75 toxic activity could be detected in the free volume of the column, which was indicative of the fact that the molecular weight of the thermostable enterotoxin was about 70,000 daltons and gr ... | 1980 | 6160702 |
| receptor mediated gonadotropin action in the ovary. modulation of progesterone response in isolated rat ovarian cells by gonadotrophin, cholera enterotoxin and cyclic nucleotides: requirement for rna and protein synthesis. | 1980 | 6161508 | |
| characterization of vibrio cholerae protease activities with peptide digest analysis. | a simple method for the analysis of microbial proteases is described that was used to characterize the proteolytic activities of various vibrio cholerae isolates. this method utilized the unique peptides generated from the degradation of a standard protein by proteases of various specificities. these peptides were analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. the unique patterns of peptides seen in gels can be used to type proteases according to their relative specificit ... | 1981 | 6161944 |
| enzymically-mediated changes in murine mammary adenocarcinoma cell membrane induces changes in lymphoid tissue immune ribonucleic acids. | a cell suspension derived from a single murine spontaneous mammary adenocarcinoma was resolved on a linear gradient of ficoll, into twelve distinct neoplastic cell subpopulation. a second cell suspension, also derived from a single murine mammary adenocarcinoma was first treated with vibrio cholera neuraminidase (vcn) then was resolved on an identical gradient of ficoll into twelve distinct subpopulation. each cell population was seeded and allowed to proliferate. the cell subpopulations differe ... | 1980 | 6165333 |
| different cell-surface receptor determinants of antigenically similar influenza virus hemagglutinins. | two influenza virus substrains, a/ri/5-/57 and a/ri/5+/57, with antigenically similar hemagglutinins and neuraminidases but with different properties of elution from erythrocytes, have been examined for the specificity of their interaction with cell surface sialyloligosaccharides. this was accomplished by using erythrocytes treated with vibrio cholerae neuraminidase to remove sialic acids, and then modified with cmp-neuac and three purified sialyltransferases to contain either the neuac alpha 2, ... | 1981 | 6167577 |
| [determination of vibrio cholerae enterotoxin by the passive immune hemolysis technic]. | to determine the antigenic determinants of cholera toxin, the passive immune hemolysis test was used. this test, proved to be highly sensitive (100-200 pg/ml) and specific, yielded results quicker than all other immunological methods for the determination of cholera toxin. the study of 36 cholera and nag-vibrio strains revealed that v. cholerae synthesized the greatest amount of the toxin, whereas v. eltor formed a heterogenous group, comprising strains capable of synthesizing the toxin in consi ... | 1981 | 6168143 |
| [epidemiology of cholera in the world. development between 1970 and 1980]. | the authors present a general review of ten year evolution of the 7th pandemic of cholerae. they discuss the official data known from the country declarations. from the epidemiological features they distinguish a hydric dilution model of cholerae (few cases, few carriers, endemicity) and a direct inter-human contamination type (epidemic outbreaks, no endemicity). | 1981 | 6170470 |
| isolation of special antibodies which react only with homologous enterotoxins from vibrio cholerae and enterotoxigenic escherichia coli. | cholera enterotoxin (ct) and heat-labile enterotoxin (lt) produced by enterotoxigenic escherichia coli share a common antigenic determinant. in addition, ct and lt each have a unique antigenic determinant. antisera were prepared by immunoaffinity chromatography against these unique antigenic determinants, that is, antiserum that reacted with ct but not with lt and antiserum that reacted with lt but not with ct. antiserum against the common antigenic determinant to ct and lt was also prepared by ... | 1981 | 6171516 |
| use of the india ink immuno-reaction for the rapid detection of enteric pathogens in two area of nigeria. | the india-ink immuno-reaction (iir) was used as a simple, convenient procedure for the detection of carriers of enteric organisms in an unselected sample of patients attending a mission clinic at kubacha in a remote area of kaduna state, northern nigeria. to assess the reliability of this procedure in difficult working conditions a similar population from the same clinic was subsequently examined by routine bacteriological culture techniques. because of a temporary shortage of suitable anti-sera ... | 1981 | 6171592 |
| induction by cholera toxin of synchronous divisions in vivo in the epidermis resulting in hyperplasia. | intracutaneous injection of cholera toxin, exotoxin of vibrio cholerae, into the dorsal skin of mice, rats, and hamsters at doses of greater than 0.1 ng evoked an acute reaction at the site of injection, which was characterized histologically by an edematous reaction in the dermis and mitotic stimulation in the epidermis. mitotic and labeling induces of basal cells of the mouse epidermis showed two peaks at 24 and 48 hr after injection, thereby producing epidermal hyperplasia. the thickness of t ... | 1981 | 6171825 |
| [nonselective mechanism of antibody-induced stable antigenic variability of microorganisms. iii. suggested mechanism of variability of certain microorganisms]. | 1982 | 6178238 | |
| serological comparison of two collections of vibrio cholerae non o1. | two large, independently obtained collections of vibrio cholerae non o1, containing 59 and 67 reference strains, respectively, were compared serologically in four laboratories. twenty strains in each collection were considered identical, and an additional 16 strains in each collection were probably identical. twenty-eight unique strains were identified, and inconclusive results were obtained with 25 strains. nine strains were not considered v. cholerae in at least one testing laboratory. of thes ... | 1982 | 6181089 |
| quality of antisera used in the diagnosis of cholera. | 1982 | 6181361 | |
| monoclonal antibodies against vibrio cholerae lipopolysaccharide. | a cell line producing monoclonal antibodies directed against the core region of vibrio cholerae lipopolysaccharide has been established. these antibodies were inhibited by lipopolysaccharide preparations of both o-group 1 vibrios and some non-o-group 1 vibrios as detected in enzyme-linked immunosorbent assay-inhibition experiments. coagglutination experiments with monoclonal and polyclonal antibodies adsorbed to protein a-carrying staphylococci were performed. all v. cholerae strains tested, reg ... | 1982 | 6183214 |
| [improved method of releasing the phage from pseudolysogenic clones of vibrio cholerae]. | 1982 | 6184536 | |
| mapping of a gene in vibrio cholerae that determines the antigenic structure of cholera toxin. | in ouchterlony-type immunodiffusion gels, the cholera toxin produced by the classical vibrio cholerae strain 569b was indistinguishable from the cholera toxin of the eltor strain rj1. however, the cholera toxin produced by both of these strains was incompletely cross-reactive with the cholera toxin produced by the eltor strain 3083-2. the allele of the gene responsible for the 569b and rj1 type of toxin was designated vct-1, and the allele responsible for the 3083-2 type of toxin was designated ... | 1982 | 6185422 |
| [immunoenzyme complex based on a polyfunctional carrier for identification and detection of microorganisms]. | 1982 | 6185754 | |
| immunochemical analysis of the determinant recognized by a monoclonal antibody (mbr1) which specifically binds to human mammary epithelial cells. | a monoclonal antibody (mbr1) raised against a membrane preparation (cm) of a human breast cancer line (mcf-7) and characterized as mammary gland epithelium associated (s. mènard, e. tagliabue, s. canevari, g. fossati, and m. i. colnaghi. generation of monoclonal antibodies reacting with normal and cancer cells of human breast. cancer res., 43:1295-1300, 1983), was used to biochemically define and partially purify its target antigen. the antigenic activity recognized by mbr1 was unaffected by tre ... | 1983 | 6186373 |
| purification and some properties of a non-o1 vibrio cholerae enterotoxin that is identical to cholera enterotoxin. | cholera-like enterotoxin was isolated and purified from the culture supernatant of a non-o1 strain of vibrio cholerae, e8498, isolated from the environment. enterotoxin was purified by aluminum hydroxide absorption and elution and successive gel filtrations on sephadex g-100, bio-gel a-5m, and sephadex g-75. purified enterotoxin gave a single stained band on polyacrylamide gel disc electrophoresis, and the mobility was the same as that of cholera enterotoxin. the specific biological activity of ... | 1983 | 6188694 |
| studies on alkaline phosphatase, catalase and z-galactosidase in vibrio el tor under normal and rifampicin resistant conditions. | alkaline phosphate, catalase and beta-galactosidase activities of vibrio et tor were decreased after acquisition of resistance towards rifampicin. zn2+, mn2+ and edta inhibited alkaline phosphatase which is most active with p-nitrophenylphosphate as substrate while mg2+ was found to suppress alkaline phosphatase activity. removal of edta however, restores the original activity. rifampicin could not induce mutation of lactose nonfermenting vibrio el for cells allowing them to grow on lactose as s ... | 1982 | 6189376 |
| biological activities of enterotoxin from vibrio cholerae non-01. | the specific antiserum 54(2) prepared in rabbits by combined intraperitoneal and intravenous immunization with the enterotoxin from vibrio cholerae non-01 was found to neutralize the enterotoxin biologic activity expressed by rabbit skin vascular permeability and hemorrhage factors. the inhibition of biologic activity was also observed when using antiserum to choleragen, but choleragen could not be neutralized by specific serum 54(2). the enterotoxin was also inactivated when heated at 100 degre ... | 1983 | 6193168 |
| prophylactic significance of the nonlipopolysaccharide antigens of vibrio cholerae. | the infant-mouse cholera model was used for evaluation of the immunoprophylactic significance of the nonlipopolysaccharide antigens of vibrio cholerae. the protective efficiency of antibodies to the nonlipopolysaccharide components of the 569b strain was much greater than that of antibodies to the lipopolysaccharide. protective nonlipopolysaccharide antigens were not detected in two other strains, however; the possible basis for this restricted distribution was considered in light of studies fro ... | 1983 | 6195273 |
| [various features of the serotyping of vibrio cholerae el tor serologic variant inaba]. | 1983 | 6195419 | |
| [titration of vibrio cholerae enterotoxin on the model of staphylococcus aureus 209 p. uv-2 mutant]. | 1983 | 6195442 | |
| characterization of monoclonal antibodies that react with unique and cross-reacting determinants of cholera enterotoxin and its subunits. | seventeen selected hybridoma cell lines that produced monoclonal antibodies against cholera enterotoxin (ct) were isolated and characterized. all of the monoclonal antibodies contained the kappa light chain; 14 were of the immunoglobulin g1 (igg1) isotype and 3 were igg2a. the 17 monoclonal antibodies were divided into a minimum of seven different specificity groups based on their abilities to bind to the following purified test antigens in solid-phase radioimmunoassays: ct, the a and b polypept ... | 1983 | 6196297 |
| [disc agglutination reactions for accumulation, isolation and identification of vibrio cholerae and vibrios not agglutinated by 01-serum]. | 1983 | 6196534 | |
| structure of the o-chain of the phenol-phase soluble cellular lipopolysaccharide of yersinia enterocolitica serotype o:9. | the phenol-phase soluble cellular lipopolysaccharide isolated by the phenol/water extraction method from yersinia enterocolitica serotype o:9 cells was shown by hydrolytic, periodate oxidation, methylation and nuclear magnetic resonance studies to be an s-type lipopolysaccharide with a linear o-antigenic polysaccharide of 1,2-linked 4,6-dideoxy-4-formamido-alpha-d-mannopyranosyl units. the serological cross-reactivity between y. enterocolitica serotype o:9 and the lipopolysaccharides of vibrio c ... | 1984 | 6199199 |