Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| super suppressors in neurospora crassa i. induction, genetic localization and relationship to a missense suppressor. | genetic analyses have been made to test the feasibility of using coincident reversions to prototrophy of multiple mutants to select super suppressors (ssu) in neurospora crassa. of five double-mutant strains examined, only those mutant combinations in which both members had the properties of nonsense mutations did revert coincidently. forty-eight genetically purified coincident revertants were crossed to the wild type, and each was shown to contain a suppressor mutation. five super suppressors w ... | 1972 | 4260182 |
| the separation of three allosterically inhibitable 3-deoxy-d-arabino-heptulosonate 7-phosphate synthases from extracts of neurospora crassa and the purification of the tyrosine inhibitable isoenzyme. | 1972 | 4260319 | |
| arginyl-transfer ribonucleic acid and synthetase of neurospora crassa. | 2013 | 4260497 | |
| circular dna from mitochondria of neurospora crassa. | 1972 | 4260513 | |
| repair of ultraviolet light-induced damage to the deoxyribonucleic acid of neurospora crassa. | a method is described for labeling a specific pyrimidine in the deoxyribonucleic acid (dna) of neurospora crassa. in cells grown in the presence of [5-(3)h]-uridine, more than 97% of the radioactivity associated with the dna had been incorporated into cytosine. the specific activity of the labeled dna was approximately 3 x 10(3) counts per min per mug. the dna was isolated by elution from hydroxyapatite columns with sodium phosphate buffer (0.40 m, ph 6.8). this procedure was used to demonstrate ... | 1972 | 4260557 |
| simple and reliable method for replica plating neurospora crassa. | the details of a simple method for replica plating neurospora crassa are described. the procedure has proved to be highly reliable for replica plating of colonies arising from either ascospores or conidia. | 1972 | 4260558 |
| regulation of exocellular proteases in neurospora crassa: induction and repression of enzyme synthesis. | neurospora crassa strain 74a grown on vogel's medium containing bovine serum albumin (bsa) as principal carbon source secretes proteolytic enzymes which appear in the culture filtrate. low concentrations of sucrose (0.1%) are necessary for growth from conidia, as conidia will not germinate on bsa alone. once growth is initiated, however, protease production begins and at 5 to 6 hr growth and enzyme production are parallel. higher concentrations of sucrose (0.5-2%) repress protease synthesis. oth ... | 1972 | 4260559 |
| regulation of arginase activity by intermediates of the arginine biosynthetic pathway in neurospora crassa. | it has been found that, in neurospora crassa, arginine synthesized from exogenous citrulline was not as effectively hydrolyzed as exogenous arginine. this was explained by the observed inhibition of arginase in vitro and in vivo by citrulline. the high arginine pool formed from exogenous citrulline feedback inhibits the arginine pathway. these two factors allow exogenous citrulline to be used adventitiously and efficiently as an arginine source. finally, it was found that ornithine was a strong ... | 1972 | 4260560 |
| genetic characterization of diethylnitrosamine-induced purple adenine (ad-3) mutants in neurospora crassa. | 1972 | 4260579 | |
| pyruvate kinase of neurospora crassa: purification and some properties. | 2014 | 4260764 | |
| cooperation of mitochondrial and nuclear genes specifying the mitochondrial genetic apparatus in neurospora crassa. | enzymes involved in the expression of the mitochondrial genome in neurospora crassa are induced by chloramphenicol and ethidium bromide, which block transcription and translation of mitochondrial dna. it is concluded that most, if not all, proteins of the mitochondrial genetic apparatus are coded by nuclear genes, synthesized on cytoplasmic ribosomes, and controlled by a repressor-like mitochondrial gene product. a model explaining the coordination of nuclear and mitochondrial division cycles by ... | 1972 | 4260903 |
| genetical and biochemical evidence for further interrelationships between the polyaromatic synthetic and the quinate-shikimate catabolic pathways in neurospora crassa. | 1972 | 4261015 | |
| the intracellular site of synthesis of mitochndrial ribosomal proteins in neurospora crassa. | the intracellular site of synthesis of mitochondrial ribosomal proteins (mrp) in neurospora crassa has been investigated using three complementary approaches. (a) mitochondrial protein synthesis in vitro: tritium-labeled proteins made by isolated mitochondria were compared to (14)c-labeled marker mrp by cofractionation in a two-step procedure involving isoelectric focusing and polyacrylamide gel electrophoresis. examination of the electrophoretic profiles showed that essentially none of the peak ... | 1972 | 4261038 |
| electron microscopy of nuclear membranes during somatic nuclear separation in neurospora crassa. | 1972 | 4261058 | |
| isolation of transfer rna genes from neurospora crassa. | 1972 | 4261112 | |
| genes influencing selective fertilization in neurospora crassa. | the mutual attraction of conidia to protoperithecia of the opposite mating type was studied genetically in crosses where a mixture of conidia from two different strains, one of which was marked by an ascospore color mutant gene tan spore (ts), was applied to protoperithecia. selective fertilization was measured as the frequency of perithecia fertilized by conidia from one strain in competition with conidia from another strain. selective fertilization by a given strain varied throughout the range ... | 1972 | 4261371 |
| control of the synthesis, activity, and turnover of enzymes of sulfur metabolism in neurospora crassa. | 1972 | 4261415 | |
| purification of two multienzyme complexes in the aromatic-tryptophan pathway of neurospora crassa. | 1972 | 4261463 | |
| genetic and enzymatic analysis of a gene controlling uv sensitivity in neurospora crassa. | 1972 | 4261527 | |
| dominance modifiers in neurospora crassa: phenocopy selection and influence of certain ascus mutants. | when homozygous in zygotes, mutant alleles at the peak locus in linkage group v of neurospora crassa initiate aberrant asci that are nonlinear, in contrast to the linear asci characteristic of wild type. most mutant alleles are recessive, inasmuch as crosses of the mutant strains with wild type give linear asci. however, five different mutant alleles, when heterozygous with the wild-type allele, act in varying degrees as zygote dominants, initiating both linear and nonlinear asci, the relative p ... | 1972 | 4261623 |
| mutation induction in neurospora crassa incubated in mice and rats. | 1972 | 4261732 | |
| [study on the conidial differentiation of neurospora crassa. ii. immunological comparison of conidiogenic wild-type antigenic structures with those of 2 aconidial mutants]. | 1972 | 4262114 | |
| pyruvate kinase of neurospora crassa: effect of various ligands on the rate of inactivation by protein denaturants. | 1972 | 4262270 | |
| altered species of mitochondrial transfer rna associated with the mi-1 cytoplasmic mutation in neurospora crassa. | 1972 | 4262272 | |
| cell wall alterations associated with the hyperproduction of extracellular enzymes in neurospora crassa. | a pleiotropic mutation in neurospora (exo-1), which confers derepression of alpha-amylase, glucoamylase, beta-fructofuranosidase, and trehalase, appears to also affect the composition of the cell wall. segregants resulting from the backcross of exo-1 to the wild-type strain from which it derived are altered in the ratio of galactosamine to glucosamine in hydrolysates of isolated cell walls. conidial cell walls exhibit a marked decrease in the amount of galactosamine in both exo-1 and exo-1(+) st ... | 1972 | 4262302 |
| isolation and classification of extranuclear mutants of neurospora crassa. | four extranuclear mutants, [exn-1], [exn-2],[exn-4], and [stp-c], were obtained from n-methyl-n'-nitro-n-nitrosoguanidine-treated conidia and mycelium of neurospora crassa. the three exn mutants grow with a pronounced lag from conidia and ascospores and are female fertile, whereas [stp-c] has a stop-start growth phenotype and is female sterile. the mitochondria from all four mutants are deficient in cytochromes a+a(3) and b, but contain an excess of cytochrome c. on the basis of growth and ferti ... | 1972 | 4262391 |
| development of fertile fruit bodies in a single-strain culture of neurospora crassa. | 1972 | 4262618 | |
| [nucleus directed biosynthesis of the mitochondrial genetic apparatus in neurospora crassa]. | 1972 | 4262620 | |
| analysis of a case of mutagen specificity in neurospora crassa. iv. interactions between uv and three chemical mutagens. | 1972 | 4262635 | |
| complementation among cytoplasmic mutants of neurospora crassa. | 1972 | 4262636 | |
| mutagenic activity of 4-nitroquinoline 1-oxide and 4-hydroxyaminoquinoline 1-oxide in neurospora crassa. | 1972 | 4262705 | |
| enzymic properties of a mutant tryptophan synthase from neurospora crassa. | 1972 | 4262962 | |
| sexuality in neurospora crassa. i. mutations to male sterility. | 2014 | 4263083 | |
| sexuality in neurospora crassa. ii. genes affecting the sexual development cycle. | 1972 | 4263084 | |
| [conidial differentiation of neurospora crassa. 3. malate dehydrogenase activity of antigenic structures and its relation to conidial competence]. | 1972 | 4263229 | |
| the effect of phosphate buffer on the differential response of two genes in neurospora crassa to uv. | 2014 | 4263301 | |
| interactions between amino acid transport systems in neurospora crassa. | mutants of neurospora crassa, selected as resistant to l-canavanine and l-thialysine, are partially deficient in the uptake of basic amino acids. neutral amino acids completely inhibit uptake of basic amino acids, and this inhibition is dependent on the activity of a neutral amino acid permease. in contradistinction, mutants resistant to 4-methyl-dl-tryptophan are partially deficient in the uptake of neutral amino acids. basic amino acids completely inhibit neutral amino acid uptake, and this in ... | 1972 | 4263403 |
| acetohydroxy acid synthetase with a ph optimum of 7.5 from neurospora crassa mitochondria: characterization and partial purification. | an acetohydroxy acid synthetase (aas) has been found associated with the mitochondrial fraction of wild-type neurospora crassa. it has a ph optimum of 7.5 and is presumed to be homologous to the ph 8.0 aas that synthesizes the valine and isoleucine precursors in bacteria and yeast. the enzyme was characterized and purified 30- to 60-fold. the aas activity of intact mitochondria requires thiamine pyrophosphate (tpp), mn(2+) or mg(2+), and flavine adenine dinucleotide (fad), and is sensitive to en ... | 1972 | 4263405 |
| interaction of genes controlling ultraviolet sensitivity in neurospora crassa. | two independently segregating ultraviolet (uv) sensitivity genes in neurospora crassa interact synergistically resulting in uv sensitivity approximately twice that expected based on an evaluation of the sensitivities of the individual mutants. the mutant genes singly and together reduce photoreactivation (pr) in vivo although a pr enzyme is produced which exhibits normal activity in vitro. | 1972 | 4263406 |
| uncoupling of the recbc atpase from dnase by dna crosslinked with psoralen. | exonucleolytic cleavage of dna by the recbc dnase is accompained by a dna-dependent atp hydrolysis that ceases when the dna that has been digested to a limit. on the other hand, dna that has been crosslinked by 4,5',8-trimethylpsoralen in the presence of 360-nm light remains an effective cofactor in the atpase reaction, but is resistant to digestion by the enzyme. psoralentreated dna is degraded by pancreatic dnase, micrococcal nuclease, and escherichia coli b restriction enzyme, but not by neur ... | 1972 | 4263506 |
| activation of membrane-bound adenylate cyclase by glucagon in neurospora crassa. | membrane-bound adenylate cyclase in neurospora crassa is activated by glucagon. half-maximal effect is observed at hormone concentrations of about 10 nm. after solubilization of the enzyme with lubrol-px, the glucagon effect is lost. incubation of neurospora cells with glucagon leads to a decrease in the activity of glycogen synthetase (ec 2.4.1.11) and to an increase in the activity of glycogen phosphorylase (ec 2.4.1.1) and in the rate of glycogenolysis. | 2014 | 4263508 |
| adenylate cyclase activity in neurospora crassa. ii. kinetics. | 1972 | 4263616 | |
| the regulation of nitrate reductase in neurospora crassa. | 1972 | 4263853 | |
| the effect of thiourea on ureide metabolism in neurospora crassa. | 1972 | 4263857 | |
| an inhibitor of ribonucleic acid polymerase from neurospora crassa. | 1972 | 4263858 | |
| purification and stability of the multienzyme complex encoded in the arom gene cluster of neurospora crassa. | 1972 | 4263953 | |
| ribosomal rna genes of neurospora: isolation and characterization. | dna sequences in neurospora crassa that code for ribosomal rna have been isolated in a highly purified state by dna-rna hybridization. about 100 separate ribosomal rna genes exist in each nucleus. these genes are composed of repeated sequences that are present about 100 times per nucleus. the individual members of this group of dna sequences are essentially identical. | 1972 | 4264050 |
| [isolation and properties of plasma membranes of neurospora crassa mycelium]. | 2014 | 4264117 | |
| interactions of phenylalanyl transfer ribonucleic acid synthetase of neurospora crassa with valyl transfer ribonucleic acid of escherichia coli. | 1972 | 4264131 | |
| permeability problems encountered when treating conidia of neurospora crassa with rna synthesis inhibitors. | 1972 | 4264155 | |
| cytochrome b in neurospora crassa mitochondria. a membrane protein containing subunits of cytoplasmic and mitochondrial origin. | 1972 | 4264399 | |
| the kinetics of l-aspartate transport in neurospora crassa conidia. | 1972 | 4264473 | |
| mutagenicity of chemical carcinogens in neurospora crassa. | 1972 | 4264527 | |
| a possible causal relationship between iron deficiency, inhibition of dna synthesis and reduction of meiotic recombination frequency in neurospora crassa. | 1972 | 4264533 | |
| effect of 8-azaguanine on polyribosomes of neurospora crassa. | 1972 | 4264601 | |
| induction of mitochondrial rna polymerase in neurospora crassa. | 1972 | 4264635 | |
| direct induction in wild-type neurospora crassa of mutants (qa-1 c ) constitutive for the catabolism of quinate and shikimate. | a color test has been developed for the selection and identification of mutants in neurospora crassa, constitutive for the three normally inducible enzymes which convert quinate to protocatechuate. by this means seven such mutants have been recovered after ultra violet irradiation of wild type and have been shown to be allelic (or very closely linked) to the qa-1(c) mutants previously obtained by other means. thus, the regulation of the synthesis of these three catabolic enzymes is indicated to ... | 1972 | 4264707 |
| genetic and metabolic control of sulfate metabolism in neurospora crassa: a specific permease for choline-o-sulfate. | 1972 | 4265021 | |
| delta-aminolaevulinate dehydratase, the regulatory enzyme of the haem-biosynthetic pathway in neurospora crassa. | the activity of delta-aminolaevulinate dehydratase is very low in the mould neurospora crassa compared with the activities detected in bacterial and animal systems. the enzyme is inducible in iron-deficient cultures by addition of iron and is repressed by protoporphyrin. the properties of the purified enzyme indicate its allosteric nature and susceptibility to feedback inhibition by coproporphyrinogen iii. neurospora extracts also contain a protein inhibitor of the enzyme and a small-molecule ac ... | 1972 | 4265023 |
| [metabolic products of microorganisms. 115. uptake of iron by neurospora crassa. i. to the specificity of iron transport]. | 1973 | 4265135 | |
| control of acetohydroxy acid synthetase in neurospora crassa. | 1972 | 4265245 | |
| [neurospora crassa pyruvate dehydrogenase: interconversion due to phosphorylation and dephosphorylation]. | 1972 | 4265372 | |
| adenylate cyclase activity in lubrol-treated membranes from neurospora crassa. | 1972 | 4265406 | |
| alkaline phosphatases of neurospora crassa. 3. effects of ph and mechanism of action. | 1973 | 4265429 | |
| genetic alterations at the molecular level in x-ray induced ad-3b mutants of neurospora crassa. | 2014 | 4265447 | |
| thymidine 2'-hydroxylation in neurospora crassa. | 1972 | 4265566 | |
| the isolation of the components of the anthranilate synthetase complex from neurospora crassa. | 1973 | 4265643 | |
| sterol mutants of neurospora crassa: their isolation, growth characteristics and resistance to polyene antibiotics. | 1973 | 4265660 | |
| [effect of 8-azaadenine on the accumulation of high-polymer inorganic polyphosphates in neurospora crassa]. | 1971 | 4265841 | |
| the effects of branched chain fatty acid incorporation into neurospora crassa membranes. | 1972 | 4265873 | |
| tryptophan transport in neurospora crassa by various types of mtr revertants. | 1972 | 4265907 | |
| aryl sulfatase in ascospores of neurospora crassa. | neurospora crassa ascospores normally do not contain aryl sulfatase even when formed under conditions of sulfur limitation. however, when one of the parental strains is the nonrepressible mutant scon(c), the resulting (mixed) ascospores contain significant levels of aryl sulfatase even when formed under conditions of sulfur abundance. | 1973 | 4265939 |
| conidial repression by phenethyl alcohol and its serological consequences in neurospora crassa. | 1972 | 4265955 | |
| the isolation of histone from neurospora crassa. | 1973 | 4266136 | |
| role of lysine and -n-trimethyllysine in carnitine biosynthesis. i. studies in neurospora crassa. | 1973 | 4266139 | |
| preparation of mitochondrial membrane proteins from neurospora crassa: prevention of lipid autoxidation damage by an antioxidant. | 2014 | 4266161 | |
| life cycle of neurospora crassa viewed by scanning electron microscopy. | scanning electron microscopy was used to examine the major stages of the life cycle of two wild-type strains of neurospora crassa shear and dodge (st. lawrence 3.1a and 74a): mycelia, protoperithecium formation, perithecia, ascospores, ascospore germination and outgrowth, macro and microconidia, and germination and outgrowth of macroconidia. structures seen at the limit of resolution of bright-field and phase-contrast microscopes, e.g., the ribbed surface of ascospores, are well resolved. new de ... | 1973 | 4266170 |
| differential gene action in neurospora crassa. | molecular hybridization experiments with pulse-labeled total ribonucleic acid (rna) or isolated nonribosomal rapidly labeled rna species and deoxyribonucleic acid from growth periods of 8, 16, and 24 hr of neurospora crassa showed differential transcription. hybridization competition experiments between rna species isolated from 8, 16, and 24 hr of growth showed qualitative differences in the types of rna synthesized during these periods. | 1973 | 4266171 |
| distinct kynureninase and hydroxykynureninase activities in microorganisms: occurrence and properties of a single physiologically discrete enzyme in yeast. | (i) saccharomyces cerevisiae grown in the presence of 1.0 mm l-tryptophan slowly excreted fluorescent material that was chromatographically identifiable as 3-hydroxyanthranilate but did not excrete detectable amounts of anthranilate nor rapidly deplete the medium of l-tryptophan. under similar growth conditions, neurospora crassa rapidly excretes anthranilate and rapidly depletes the medium of l-tryptophan. (ii) chromatographic analysis of crude extracts from yeast revealed a single kynureninase ... | 1973 | 4266242 |
| histidine uptake in mutant strains of neurospora crassa via the general transport system for amino acids. | a transport double mutant of neurospora crassa has been isolated that has only one of the three transport systems capable of l-histidine uptake. the substrate specificity of the remaining transport system, termed the general transport system, has been fully characterized with regard to the contributions to binding of the side chain, the alpha-amino group, and the carboxylate group. the positively charged alpha-amino group is necessary for binding; the negatively charged carboxylate group is of l ... | 1973 | 4266243 |
| increased viability of a strain of neurospora crassa after treatment with ultraviolet radiation or other agents. | a strain of neurospora crassa with low viability but near normal germination shows a two- to sixfold increase in the number of colonies formed after treatment with ultraviolet radiation, x radiation, nitrous acid, or heat (50 c). effective dosages of these agents produce moderate killing of the wild type. | 2014 | 4266244 |
| dissociation of mitochondrial ribosomes of neurospora crassa by a bacterial dissociation factor. | 1973 | 4266973 | |
| structure of the mitochondria of neurospora crassa as revealed by thin sectioning and freeze-etch techniques. | 1972 | 4267202 | |
| adenine nucleotide levels in neurospora, as influenced by conditions of growth and by metabolic inhibitors. | by a combination of luciferase and fluorescence methods adenine nucleotide pools in neurospora crassa have been examined under various conditions of growth and metabolic inhibition. during sustained exponential growth (25 c, shaking liquid cultures), the intracellular adenosine 5'-triphosphate (atp) concentration, [atp](i), rises slowly from the conidial level near 1 mm (1 mmol/kg of cell water) to a maximum of 2.0 to 2.5 mm at 14 h, after which it slowly declines. the adenosine 5'-diphosphate a ... | 1973 | 4267534 |
| an inhibitory factor affecting ribonuclease activity in neurospora crassa. | 1973 | 4267553 | |
| the ribonuclease activities of the single-strand-specific nucleases of neurospora crassa. | 1973 | 4267583 | |
| identification of sexual hormones in neurospora crassa. | 1972 | 4267851 | |
| transport of c 4 -dicarboxylic acids in neurospora crassa. | 1973 | 4268075 | |
| particle weights of active ribosomal subunits from neurospora crassa. | 1973 | 4268077 | |
| virus-like particles in an estranuclear mutant of neurospora crassa. | a particulate fraction not present in wild-type cells has been isolated from the cytoplasm and from lysed mitochondria of the respiratory-deficient extranuclear mutant "abnormal-1" of neurospora crassa. the particles have a density between 1.13 and 1.2 g/ml. they appear in thin sections after oso(4) fixation as virus-like polymorphic vesicles containing an electron-dense nucleoid of 120-170 nm in diameter. the central core is surrounded by one or two "unit membrane" envelopes of 100 a thickness. ... | 1973 | 4268098 |
| growth regulation in neurospora crassa. effects of nutrients and of temperature. | 1973 | 4268110 | |
| branded chain amino acid aminotransferases of neurospora crassa. | 1973 | 4268214 | |
| [interactions between the amino acid pool and l-amino-acid oxidase in neurospora crassa]. | 1972 | 4268302 | |
| ribosomal rna synthesis in mitochondria of neurospora crassa. | 1973 | 4268438 | |
| different chromatographic forms of neurospora crassa nucleases specific for single-stranded nucleic acids. | 1973 | 4268627 | |
| growth of wild type and spreading colonial mutants of neurospora crassa in batch culture and on agar medium. | 1973 | 4268672 | |
| the hyphal growth unit of wild type and spreading colonial mutants of neurospora crassa. | 1973 | 4268673 | |
| regeneration of invertase in neurospora crassa. | in neurospora, invertase is predominately an extracellular enzyme, and acid phosphatase is partially external in location. both extracellular invertase and acid phosphatase were rapidly and quantitatively inactivated by acid treatment (ph 1.3). when such acid-treated cells were incubated with a suitable carbon source, a substantial regeneration of invertase activity occurred, but no restoration of acid phosphatase could be detected. the regeneration of invertase does not occur by renaturation of ... | 1973 | 4268689 |
| action of rec-3 on recombination near the amination-1 locus of neurospora crassa. | 1973 | 4268716 | |
| adenylate cyclase activity in neurospora crassa. 3. modulation by glucagon and insulin. | 1973 | 4268860 |