Publications

aromatizing activity of placental microsomal fractions from ewes in late gestation.	placental microsomes from eight domestic sheep at 136-146 days of gestation were incubated with radioactive androstenedione, testosterone and dehydroepiandrosterone. aromatizing activity was examined in the presence and absence of cortisol and the rates of both oestrone and oestradiol synthesis were measured. oestrone predominated in preference to oestradiol in most of the incubations, a result opposite to that found with human placentae. the sharp increase in the rate of oestradiol production f ...	1975	124760
demonstration of an active c17-c20 lyase in the sheep placenta.		1975	124774
[possible causes determining the developmental rhythm of populations of the nasopharyngeal gadfly of sheep, oestrus ovis l. (diptera, oestridae)].	on the basis of observations undertaken in azerbaijan and available literary data the author considers the hypotheses concerning the reasons causing the delay of the ist instar larvae development and determining the age structure changes in population of oestrus ovis l. within a year. the main reasons are as follows: factors depending on the population density at the larval phase, the light day duration within the life cycle of the botfly females.	1975	124845
the effect of fenbendazole on nematode parasites in experimentally infected lambs.	fenbendazole given orally to experimentally infected lambs at a dose rate of 5 mg per kg was found to be 100 per cent effective against three and 10-day larave and also against 20-day adults of h contortus, o circumcincta, n battus and t colubriformis. the same dose was also 100 per cent effective against 10-day, 17-day larvae and 27-day adult d filaria.	1975	124986
[experience with controlling fascioliasis].		1975	124995
[epizootiology of fascioliasis in sheep].		1975	124996
familial and sporadic chronic neurological degenerative disorders transmitted from man to primates.		1975	125030
isolation of a low molecular weight form of plasminogen.		1975	125089
a new reliable method for evaluation of foot pad swelling as an experimental in vivo immune phenomenon.	weight determination of replicas of the feet from living mice is described as a new method for evaluating the degree of the experimentally induced foot pad swelling in immunized mice. the new method gives objective, well documentable results and offers advantage to the commonly used assay with the dial calliper gauge when there is need for a good documentation or whenever there is a large number of animals to be tested within a narrow time margin.	1975	125243
subpopulations of human thymus cells differing in their capacity to form stable e-rosettes and in their immunologic reactivity.	the majority of human thymus cells from young donors form stable e-rosettes with sheep red blood cells (srbc) that do not distintegrate after prolonged incubation at 37 degrees c. with advancing age the proportion of thymus cells forming such rosettes decreases gradually. the thymus of a patient receiving prednisone treatment was found to contain only a few cells that formed stable e-rosettes. the minor population of thymus cells that fails to form stable e-rosettes (non-rosetting or nr cells) w ...	1975	125304
a passive agglutination method using collagen-coated tanned sheep erythrocytes to demonstrate collagen-glycosaminoglycan interaction.	a haemagglutination method originally designed to detect and measure antibody has been shown to be capable of monitoring interactions of glycosaminoglycans and collagen in vitro under physiological conditions of ph and ionic strength. in this system, dermatan sulphate and chondroitin 4-sulphate interact at higher dilutions ('higher titres') with collagen than do chondroitin 6-sulphate or keratan sulphate. the results are relevant to studies of anti-collagen antibodies in connective tissue fluids ...	1975	125305
steroid entry into rete testis fluid and the blood-testis barrier.	evidence that steroids enter rete testis fluid (rtf) from the blood at varying rates was obtained during i.v. infusions into rats. testosterone and dehydroepiandrosterone were readily transferred into the fluid, whereas cholesterol was excluded. between these extremes, the appearance of radioactivity in the rtf suggested the following order of entry rate: progesterone greater than pregnenolone greater than 5-alpha-reduced androgens greater than oestrogens greater than corticosteroids. preliminar ...	1975	125308
rate of flow of digesta and electrical activity of the small intestine in dogs and sheep.	1. spiking activity of the small intestine in the conscious dog and sheep was recorded continuously from electrodes chronically implanted on the jejunum and summed at intervals of 20 sec. the activity was related to the transit time and flow rate of intestinal contents as estimated by phenol red and by dilution of continuous marker infusions respectively. also in some sheep the flow of digesta was measured directly from a cannula in the proximal part of the jejunum, and also by use of an electro ...	1975	125331
surface characteristics of synovial fluid and peripheral blood lymphocytes in inflammatory arthritis.		1975	125593
effects of mitogens on sodium-potassium transport, 3h-ouabain binding, and adenosine triphosphatase activity in lymphocytes.		1975	125654
responses of guinea-pig lymphocytes to mitogens, an antigen, and mixed leucocyte culture in media with and without mercaptoethanol and foetal calf serum.	the ability of guinea-pig spleen and lymph node cells to undergo a proliferative response in vitro in the presence of mitogens (concanavalin a and lipopolysaccharide), a specific antigen (oxidized ferredoxin), and allogeneic cells was assessed under a variety of conditions. time and dose dependency of the responses was measured in rpmi 1640, rpmi 1640 plus mercaptoethanol (me), rpmi 1640 plus foetal calf serum (fcs), and rpmi 1640 with me and fcs. mitogen responses were also measured after treat ...	1975	125723
microheterogeneity of chondroitin sulfates from various cartilages.	chondroitin sulfate fractions were isolated from different animal cartilages, including whale, cattle, sheep, ray and shark, by dowex 1 chromatography followed by ethanol fractionation. although each preparation showed a single spot when electrophoresed on cellulose acetate, both 4- and 6-sulfated disaccharides were present in chondroitinase digests of each. in particular, the main fraction of bovine tracheal chondroitin sulfate (so4/ga1n = 1) gave both the disaccharides in nearly equal amounts, ...	1975	126131
diaphragmatic activity and lung liquid flow in the unanesthetized fetal sheep.	for some time it has been suggested that breathing movements are made "in utero" and recently measurements of tracheal pressure and lung liquid flow in chronic fetal preparations have led to the hypothesis that rapid changes in these parameters are the result of respiratory muscle activity. to test this hypothesis diaphragmatic electrical activity was measured in seven chronic unanesthetized fetal sheep preparations and correlated with lung liquid flow and tracheal pressure. diaphragmatic activi ...	1975	126223
antigenic differences in (na+, k+)-atpase preparations isolated from various organs and species.	antisera to purified (na+, k+)-atpase raised in rabbits and in sheep were purified by an absorption procedure employing purified canine kidney (na+, k+)-atpase. the antibodies were fractionated into two components, one which inhibited catalytic activity, and a second which inhibited ouabain binding. under certain conditions, the fraction that inhibited ouabain binding also inhibited catalytic activity, and the effectiveness of both was dependent to some extent on the ligands present in the incub ...	1975	126235
covalent labeling of the digitalis-binding component of plasma membranes.		1975	126364
immunological adjuvants. vii. kinetic study on the adjuvant effect of wax d.		1975	126534
[immunological tolerance and inhibition of antibody formation by antigen (author's transl)].		1975	126536
chemical structure of lipopolysaccharides and endotoxin immunity.	lipopolysaccharides (endotoxins) of gram-negative bacteria consist of 2 components with distinct physico-chemical character: a heteropolysaccharide and a covalently linked lipid, termed lipid a. the chemical structure of lipid a, which represents the toxic center of lipopolysaccharides, is discussed. evidence is presented that lipid a antiserum suppresses the pyrogenic effect of lipid a and lipopolysaccharides in rabbits. the protective power of lipid a antiserum, however, is only expressed in a ...	1975	126554
characterization of a stimulating factor released by immunosuppression.	to get more information about the mechanism of stimulation of the immune response during immunosuppression under certain conditions, stimulating factor (sf) was collected 48 hours after treatment of nmri-mice with cyclophosphamide. sf was characterized by different steps of separation using centrifugation, dialysis and salt-fractionation. for demonstration of the sf animals were sensitized with srbc and given different substrates separately. the stimulation of the antibody-production was demonst ...	1975	126571
interactions of the third component of complement (c3) with cross-linked dextran. iv. adherence of lymphocytes to c3 coated dextran gel particles.	in previous studies we could show that the third component of complement (c3) is bound from normal serum to cross-linked dextran (sephadex) after activation via an alternate pathway. data presented in this paper demonstrate that a subpopulation of human lymphocytes adheries to c3 coated sephadex particles. the adhering subpopulation of lymphocytes is identical with or overlaps extensively with lymphocytes bearing easily detectable membrane ig. this phenomenon can be used for the fractionation of ...	1975	126575
peripheral blood t and b lymphocytes in men in different age groups.	peripheral blood t and b lymphocytes were determined in normal humans at different ages. spontaneous rosette formation with sheep red blood cells (srbc) was used as a marker for t cells. b cells were detected by immunofluorescent staining of membrane-bound immunoglobulins. blood samples from old individuals contained significantly lower t lymphocyte numbers than those from children. this diminution of circulating t cells caused a reduction of the total lymphocyte count in the elderly persons. no ...	1975	126578
[ultrastructural localization of alkaline phosphatase and atp-ase in cyst stages of sarcocystis tenella (sporozoa, coccidia) parasitic in the esophagus of sheep (author's transl)].	the activity of adenosine triphosphatase and alkaline phosphatase was investigated at the fine structural level in the cyst stages of sarcocystis tenella parasitic in the esophagus of sheep. alkaline phosphatase reaction was observed along the outer membrane of the parasite's pellicle. the enzymatic activity was much higher on the surface of metrocytes than that of zoites, which proved to be infectious. no reaction was noted in the interior of the parasites. however, a significant amount of alka ...	1975	126600
demonstration of a mg-atpase and a na,k-atpase from the arteria carotis communis of the sheep.	besides the mg-atpase, a na,k-atpase can be demonstrated in different fractions of smooth muscles of the a. carotis communis of the sheep. the highest activity of mg-atpase is observed in the heavy microsomal fraction. the ca-ion may act as a complete substitute for the mg-ion in the mg-atpase. the proportion of na,k-atpase is between 10 and 40%, depending on the preparative conditions used in the individual fractions. fractionated salt treatment (libr, kc1, kbr) improved the assay of na,k-atpas ...	1975	126627
the effect of experimental anaemia on the levels of glutathione and glycolytic enzymes of the erythrocytes of normal and glutathione-deficient merino sheep.	the effects of experimental anaemia on the levels of reduced glutathione (gsh) and the activity of glycolytic enzymes in the erythrocytes of normal and gsh-deficient merino sheep were investigated. there was a rise in red cell gsh levels in both groups of sheep; the magnitude of this response was, however, quite different. when expressed as a percentage of the initial value, the rise in gsh level was 18% in normal and 263% in gsh-deficient animals. there was also an increase in the activities of ...	1975	126681
[effect of insulin on electric activity of sheep jejunum].	the effect of insulin on the electrical activity of the small intestine was studied in both normal and alloxan induced diabetic sheep. in normal animals the migrating myoelectric complexes recur at intervals of about 90 min. in the diabetic sheep, the complexes recur at only 2 hourly intervals and administration of insulin restored the pattern to normal. since in normal sheep, insulin slightly increases the activity and volatile fatty acids, which release insulin do likewise, one may conclude th ...	1975	126781
[insulin secretion and intestinal motility].	in dogs after feeding increased plasma insulin concentration is positively related in converting the "fasted" pattern of electrical activity into the "fed" pattern. in sheep, the release of insulin induced by a perfusion of volatile fatty acids is accompanied by similar changes in the pattern of electrical activity. the results indicate that insulin release induced by nutrients plays a major role in the control of intestinal motility in both species.	1975	126782
[immuno-cyto-adhesion and sublethal irradiation].	1. in sublethally irradiated cba mice, the relative and absolute numbers of spontaneous rosetts forming cells against sheep erythrocytes are markedly decreased in bone marrow. 2. the decrease of the absolute number of spontaneous rfc is also important in the spleen in spite of an increase of the rfc relative number above the normal values between the 8th and 12th day after irradiation. 3. the graft of normal bone marrow cells immediately after irradiation of the shielding of a medullary area dur ...	1975	126788
the effects of thymidine and its analogues on the differentiation of antibody-forming cells.	thymidine (tdr) and its analogues 5-fluorodeoxyuridine (fudr) and 5-bromodeoxyuridine (budr) inhibited the development of antibody-producing cells (pfc) in cultures of explants of rabbit spleen stimulated with sheep red cells in vitro. they were effective in this respect, even at concentrations too low to inhibit cell division. the results indicated that tdr had produced its effects by a selective action on dna and rna synthesis. in view of what is known about the mechanisms of action of tdr and ...	1975	126887
antigens of leptotrichia buccalis i. their serologic reaction with human sera.		1975	127031
antigens of leptotrichia buccalis ii. their reaction with complement fixing igm in human sera.		1975	127032
the responses of muscle spindles in sheep extraocular muscles.	1. responses from de-efferented muscle spindles in sheep extraocular muscles have been recorded in the gasserian ganglion using glass microelectrodes. 2. the afferent fibre conduction velocities ranged from 32 to 106 m/sec and most were intermediate. the distribution was unimodal. 3. the afferent responses to ramp stretches and longitudinal vibration of the muscle could not be divided into two groups, but both the dynamic indices and vibration sensitivities of the afferents increased with their ...	1975	127036
adjuvancy of streptococcal nucleic acids.	a study was performed to find out whether or not rna and dna isolated from group a streptococcal cytoplasm does possess adjuvant activity. the findings obtained indicate that the adjuvancy of streptococcal rna is very similar to that of poly i:c. the adjuvant activity of poly i:c is characterized by its capacity to increase the number of pre-existing hemolysin-producing spleen cells and by its ability to increase the development of 19s and 7s producers early in the 12-day-period of primary immun ...	1975	127450
cytochemical studies of rosette-forming cells.	two types of rosette-forming cells were identified: rosette-forming cells with membrane-bound receptors for sheep erythrocytes (e-rfc) and rosette-forming cells with fc receptors (ea-rfc). in both types of lymphocytes the activity of acid phosphatase, beta-glucuronidase, non-specific esterase and the content of glycogen were studied. a significant difference was established between e-rfc and ea-rfc lymphocytes as concerns acid phosphatase activity; corresponding mean values being 72.4 +/- 7.5 re ...	1975	127452
heteroagglutinins and spontaneous rosette-forming cells in obese strain (os) chickens.	sera of os chickens with spontaneous autoimmune thyroiditis (sat) and of normal white leghorn (nwl) controls, aged 4-20 weeks, were studied for the presence of heteroagglutinins to sheep (srbc) and rabbit red blood cells (rrbc). significantly higher frequency and titers of srbc- and rrbc-agglutinins were found in os as compared to nwl birds, the difference being more accentuated with rrbc. the number of spontaneously rosette-forming peripheral blood lymphocytes (rfc) with srbc and rrbc was deter ...	1975	127457
the postnatal development of the white pulp in the rat spleen and the onset of immunocompetence against a thymus-independent and a thymus-dependent antigen.	the spleen of the rat contains 5 well delineated compartments: a central and peripheral part of the periarteriolar lymphatic sheath (pals), the marginal zone and the follicle with centre and corona. a study was made on the development of these compartments in correlation with the onset of immunocompetence of the spleen. the spleens of animals in the age range from 1-40 days were studied with the light and electron microscopes. immunocompetence was assessed by measuring serum antibody levels 5 da ...	1975	127464
antagonism of d-lysergic acid diethylamide and mescaline by 1-methyl-1, 2, 5, 6-tetrahydropyridine-n, n-diethyl-carboxamide (thpc).	contractions of sheep umbilical vasculature induced by 5-hydroxytryptamine, mescaline and d-lysergic acid diethylamide (lsd) were antagonized by 1-methyl-1, 2, 5, 6-tetrahydropyridine-n, n-diethyl-carboxamide (thpc) 5 x 10(-4)m. thpc did not block contractile responses to angiotensin. the data are interpreted to support our previous suggestions that certain chemical entities representing portions of the lsd molecule may be effectively studied as antagonists to the hallucinogens. the present data ...	1975	127560
letter: transmission of sarcosporidiosis from dogs to sheep maintained specific pathogen free.		1975	127576
observations on epizootiology and distribution of elaeophora schneideri in montana ruminants.	seventy-four moose, 111 elk, 20 mule deer, 8 white-tailed deer, 26 prong-horn antelope, 42 domestic sheep and 3 bighorn sheep from montana or northwestern wyoming were examined post-mortem for evidence of elaeophora schneideri infection in 1973-74. fifteen percent of the mule deer and four percent of the moose were positive for adult arterial worms. this constitutes the first report of e. schneideri in mule deer in montana. no gross signs of blindness or other neurologic disorder were evident in ...	1975	127848
high dose cyclophosphamide therapy in solid tumors. therapeutic, toxic, and immunosuppressive effects.	cyclophosphamide (cy) in a total dose of 120 mg/kg was given over 2 days on one to three occasions to 12 patients with a variety of nonlymphoid solid tumors. two of 10 patients with measurable disease had a partial response. one had embryonal rhabdomyosarcoma and the other had ovarian carcinoma. in the 20 treatment courses, the mean leukocyte count was less than 1,000/mm for 7 days. thrombocytopenia was variable with a mean nadir of 87,000/mm on day 12. there were four instances of local infecti ...	1975	128408
immunological responsiveness of frozen-thawed human lymphocytes.	mononuclear cells (10--20 x 10(6)) obtained from human peripheral blood by a standard ficoll-hypaque technique were suspended in rpmi 1640 media at 4 degrees c containing 10% foetal calf serum and 7-5% dimethyl sulphoxide (dmso). two-millilitre aliquots were cooled at -1 degree c/min in a cryoson bv-4 programmed freezing system to -30 degrees c, then -5 degrees c/min to -80 degrees c and stored in liquid nitrogen vapor. on the day of testing, cell suspensions were thawed rapidly in a 37 degree c ...	1975	128429
proceedings: insulin and the control of plasma glucose concentration in chronically catheterized foetal lambs.		1975	128626
a fluorescent probe study of the lipid mobility of membranes containing sodium- and potassium-dependent adenosine triphosphatase.		1975	128692
effects of operation on immune response in cancer patients: sequential evaluation of in vitro lymphocyte function.	the effect of operation on in vitro lymphocyte function in 35 cancer patients was studied. lymphocyte proliferative responses to phytohemagglutinin (pha), poke-weed mitogen (pwm), and concanavalin a (con a) were measured by 3h-thymidine incorporation. sheep red blood cell (srbc) rosette formation also was quantitated. these tests were performed preoperatively and at 24 hours, one week, and 4 weeks postoperatively. intra-abdominal and intrathoracic procedures, transfusions, and longer operating t ...	1976	128842
[photosensitizing action of phenothiazine].		1975	128878
[prevention of sheep nose bots].		1975	128884
[influence of antio on the reproductive function of animals].		1975	128888
[influence of natural-economic factors and veterinary measures in listeriosis].		1975	128890
cardiac output in the fetal lamb: the effects of spontaneous and induced changes of heart rate on right and left ventricular output.	right and left ventricular outputs were measured continuously in fetal lambs in utero for 2 to 21 days after implantation of electromagnetic flow tranducers around the main pulmonary trunk and ascending aorta. surface pacing electrodes were implanted on the left and right atria. the intact cervical vagus nerve was stimulated by electrodes implanted around the nerve. spontaneous increased in fetal heart rate were associated with increases in both right and left ventricular outputs and spontaneous ...	1976	129010
pathogenesis of subacute spongiform encephalopathies.	the subacute spongiform encephalopathies include scrapie of sheep, transmissible mink encephalopathy, and kuru and creutzfeldt-jakob disease of man. these diseases are caused by filterable infectious agents with unique physical properties. the usual sources of infection in nature are not completely known. epidemiological evidence suggests that the agents may enter the body through breaks in the skin and mucous membranes. experimental studies of scrapie after subcutaneous inoculation demonstrated ...	1976	129025
ouabain-binding and phosphorylation of (na+ + k+) atpase treated with n-ethylmaleimide or oligomycin.	ouabain-binding and phosphorylation of (na+ mk+)-atpase (ec 3.6.1.3) of the plasma membranes from kidney were investigated after treatment with n-ethylmaleimide or oligomycin. either of these inhibitors brought about the following changes: the phosphoenzyme, formed in the presence of na+, mg2+ and atp became essentially insensitive to splitting by k+ but was split by adp. one mole of this adp-sensitive phosphoenzyme bound one mole of ouabain but the enzyme-ouabain complex was less stable than in ...	1976	129164
[influence of a sublethal irradiation on the immune response of the mouse to sheep erythrocytes].	in the cba mice, the immunological response of the spleen cells (rfc and pfc direct and indirect) against the sheep erythrocytes is highly depressed by a 400 r dose of x rays. the recovery is not complete at the 30th day after irradiation. the response of the bone marrow cells either irradiated or unirradiated to the antigenic stimulation is very low.	1975	129223
histochemical localization of mg2+-na+-k+-adenosine triphosphatase in different stages of the sheep mesonephros.	mesonephroi of sheep embryos ranging from 12 to 100 mm c.r. length were examined for the occurrence and localization of transport-atpase. native cryostat sections were incubated according to the technique of guth and albers for demonstrating the nitrophenylphosphatase activity of mg2+-na+-k+-adenosine triphosphatase. the basal cytoplasm of the collecting tubule of the narrow segment of the distal tubule exhibit strong activity, the wide segment of the distal tubule is moderately active. glomerul ...	1975	129445
[observation and experiences made during an outbreak of q-fever at simmerath/eifel in 1973 (author's transl)].		1975	129733
[testing insecticides in melophagiasis of sheep].		1975	129906
[veterinary sanitary assessment of the slaughter products from animals with nephritis].		1975	129910
[prevention of helminthiasis in sheep in kazakhstan].		1975	129934
[preparation of rams for the mating season under summer pasturing conditions].		1975	129942
a comparison of antigenic structure and phage pattern with biochemical properties of staphylococcus aureus strains isolated from sheep.	of 84 staphylococcus aureus strains isolated from the anterior nares of healthy sheep and from the udders of ewes suffering from purulent mastitis the 89 per cent belonging to the c biotype contained agglutinogen h2 as well as polysaccharide abeta. ninety-five per cent of the c biotype strains were lysed by the bovine phage 78, the human phage set giving only weak reactions at rtd x 100. two pigment-negative deficit variants as well as three unclassified strains gave similar results while three ...	1976	130055
further purification of the lymphocyte inhibiting extract from the thymus.	a crude thymic extract, demonstrated to possess both immunosuppressive activity on t lymphocytes in vivo, and inhibitory action on dna synthesis in t lymphocytes in vitro, has been purified by ultra-filtration and ion exchange chromatography procedures. the immunosuppressive activity was found to be associated with a high molecular weight fraction (greater than 50,000 daltons), devoid of immunosuppressive properties, a basic peptide has been isolated which retains the in vitro inhibitory activit ...	1975	130147
t and b cells and cell-mediated immunity in mycosis fungoides.	t anb b cells in peripheral blood were evaluated in 13 patients with mycosis fungoides (mf) and in two patients with sézary's syndrome. t cells were identified by their capacity to bind sheep red blood cells to their surfaces and the b cells were identified by the presence of surface immunoglobulins in immunofluorescence assay. seven patients with mf and two with sézary's syndrome were shown to have t-cell values below normal and elevated levels of null cells, i.e., cells with markers for neithe ...	1976	130203
schedule-dependent effect of phase-specific cytotoxic agents on production of hemolytic plaque-forming cells.	the proliferative phase of the primary response of mice to sheep red blood cells (srbc) was used to study quantitatively the schedule-dependent effect of four phase-specific cytotoxic agents: 1-beta-d-arabinofuranosylcytosine (ara-c), methotrexate (mtx), 5-fluorodeoxyuridine (5-fudr), and 5-fluorouracil (5-fu). the multiple injections of ara-c- given 24-60 hours after srbc injection caused a 100-fold greater inhibition in the production of direct hemolytic plaque-forming cells (pfc) on day 4 tha ...	1976	130495
chemotherapy of experimental bovine petechial fever.	a dithiosemicarbazone was compared with two tetracycline formulations in the treatment of bovine petechial fever (bpf) in experimentally infected sheep, and was then used to treat the disease in experimental cattle. the dithiosemicarbazone was found to be more efficacious than either of the other two drugs in treating ovine bpf, and also to be effective against bpf in cattle.	1976	130668
[activity of some carbohydrate-metabolizing enzymes in sheep skin].	the activity of carbohydrate metabolism certain enzymes [hexokinase (ec 2.7.1.1.), glucokinase (ec 2.7.1.2), phosphofructokinase (ec 2.7.1.11.1), glucoso-6-phosphate-dehydrogenase (ec 1.1.1.49.)] was studied in the sheep skin when adding vitamin a, sodium sulphate and insulin to the basic ration. the activity of the studied enzymes in the skin was established to be rather high and depend to a considerable extent on feeding, seasonal and hormonal factors. in summer the activity of such enzymes as ...	1976	130704
[distribution of urolithiasis among animals in a dry climate zone].		1976	130719
[a rapid method of determining copper in pathological material].		1976	130721
the epidemiology and control of some nematode infections in grazing animals.		1976	130791
treponemal antigen in immunopathogenesis of syphilitic glomerulonephritis.	a patient with syphilitic glomerulonephritis had a renal biopsy and was treated for secondary syphilis. light, electron, and immunofluorescence microscopic studies revealed an acute proliferative glomerulonephritis with subepithelial, intramembranous, and subendothelial immune complex deposits containing igg, iga, igm, c4, and c3. similar local deposits containing predominantly igm were noted in areas of mesangial proliferation. indirect fluorescent antibody studies employing rabbit treponemal a ...	1976	130804
lymphocyte transformation induced by autologous cells. iv. human t-lymphocyte proliferation induced by autologous or allogeneic non-t lymphocytes.	an autologous mixed lymphocyte reaction was demonstrated between t and non-t lymphocytes. sheep erythrocyte rosetting was used to separate human lymphocytes into t and non-t lymphoid preparations. non-t lymphocytes stimulated the proliferation of autologous t lymphocytes. the cell in this preparation that was most stimulatory had the characteristics of a k lymphocyte. the allogeneic mixed lymphocyte reaction was also shown to reflect the proliferation of t lymphocytes stimulated by allogeneic no ...	1976	131174
a comparative study of skeletal and cardiac tropomyosins: subunits, thiol group content and biological activities.	the subunit composition, the thiol group content and the biological activities of cardiac tropomyosins (tm) of various animal species were compared. cardiac tm from small animals such as rabbit, guinea-pig, rat and dog contain 2 sh/mole and were resolved into one band on sds and acid urea electrophoresis and into two bands on alkaline urea electrophoresis. chicken cardiac tm likewise gave one band and it contains 4 sh/mole. in contrast pig, sheep and human cardiac tm contain respectively 2.6, 2. ...	1976	131298
inhibition of in vitro immune responses by a fraction from seminal plasma.	we studied the inhibitory effect of a fraction of bovine seminal plasma on in vitro lymphocyte responses to specific and nonspecific ligands. seminal plasma was fractionated by sephadex g-100 chromatography, and the inhibitory component was found to have a molecular weight of above 100,000 daltons. this fraction was devoid of lymphocytotoxicity and could inhibit, in a dose-dependent mode, both the primary antibody response of normal mouse spleen cells to the thymus-dependent antigen sheep erythr ...	1976	131370
[uzbekistan: action, problems, plans].		1976	131408
characterization of a t-lymphocyte inhibitor in the serum of tumour-bearing mice.	sera from mice with large tumours from a variety of tissue types and sources have been shown to contain substances capable of suppressing the proliferative response of normal mouse lymphocytes to concanavalin a (con a), bacterial endotoxin (lps) and allogeneic cells. the present paper deals with studies on the nature of these inhibitory materials using mainly a methylcholanthrene-induced rhabdomyosarcoma in dba/2j mice. it was found that a material responsible for inhibition of the con a respons ...	1976	131782
effect of mercuric chloride on the structure and function of the kidney of sheep.		1976	131813
an intra-abdominal chamber for continuous long-term observation of the sheep ovary.	rupture of the ovarian follicle (ovulation) is a clinically important event in reproduction, and its prediction or detection has been the object of many investigations. direct observation is presently the only conclusive concurrent evidence of ovulation and is, therefore, necessary in investigations on the validity and precision of signals hypothesized to be time-related to ovulation. for this purpose, an ovary observation chamber, with a kink-resistant polyvinyl chloride viewing conduit, has be ...	1976	132200
[electromyographic analysis of motor perturbations linked with gastrointestinal strongyloidiasis].	the effects of experimental infection of lambs with third stage trichostrongylus larvae are described. preceding diarrhea, disturbances in the motility of the reticulum, abomasum and jejunum were observed by electromyography. disappearance of the migrating myoelectric complexes occurred about 24 h before diarrhea and was accompanied by a decrease in both the frequency of reticular contractions and of contractions propagated through the antro-duodenal junction. the significance of these findings ...	1975	132260
[prevalence of q fever in czechoslovakia (author's transl)].		1976	132287
[differentiation of mycobacteria in agar column according to lebek (author's transl)].		1976	132296
immunochemical behavior of sheep non-precipitating antibodies isolated by immunoadsorption.		1976	132396
b and t cells in lymphoid tissues of human appendix.	human appendix lymphoid cells (hal) react very strongly to stimulation with concanavalin a, strongly to stimulation with phytohaemagglutinin, and weakly but definitely to stimulation with lipopolysaccharide. from the results of rosette formation assay, cytotoxicity tests with anti-t cell antiserum or anti-b cell antiserum, cell surface or intracellular immunoglobulin staining with fluorescein-conjugated rabbit anti-fab of human immunoglobulin serum, and plaque-forming cell (pfc) assay, it was co ...	1976	132409
studies on heart phosphofructokinase. use of fructose 6-sulfate as an alternative substrate to study the mechanism of action and active site specificity.	fructose 6-sulfate was synthesized by direct sulfurylation of fructose and was isolated by two selective steps: (a) conversion of the 6-sulfuryl ester to fructose 1-phosphate-6-sulfate with phosphofructokinase; (b) conversion of fructose 1-phosphate-6-sulfate to fructose 6-sulfate by fructose-1,6-diphosphatase. utilizing crystalline sheep heart phosphofructokinase, kinetic studies with the alternative substrate were carried out at ph 8.2 which is optimal for nonallosteric kinetics. the data are ...	1976	132439
[discovery of viroids and possible relationship with human and veterinary medicine].	the researches of diener and co-workers and those of the semancik's group, have recently established that some plant diseases, such as potato spindle tuber, citrus exocortis disease and chrysanthemum stunt, are caused by a new class of pathogens, named viroids. these are the smallest known agents (they are smaller than viruses) having a molecular weight of ca 10(5) daltons, and composed of a highly structured rna, rich in guanine-cytosine base pairs without a capsid. little is known about the or ...	1975	132907
adjuvant and mitogenic properties of a supernatant fraction of sonically treated myobacterium bovis (bcg).	a water-soluble, oil-free supernatant fraction of sonically treated bcg (bcg-ss) was shown to be an immunological adjuvant and a mitogen. when bcg-ss and sheep erythrocytes (srbc) were injected intravenously into mice, the plaque-forming cell (pfc) response was 10 times greater than that induced by injection of srbc alone. circulating antibody responses to srbc and to bovine serum albumin were also enhanced by bcg-ss. the in vitro enhancement of pfc and circulating antibody responses did not req ...	1976	133083
specific sodium-22 binding to a purified sodium + potassium adenosine triphosphatase. inhibition by ouabain.	analysis of sodium-22 binding to purified sodium + potassium ion-activated adenosine triphosphatase (na+, k+)-atpase reveals the presence of two classes of binding sites. the higher affinity site (kd = 0.2 mm) binds 6 to 7 nmol of sodium per mg of protein. pretreatment of (na+, k+)-atpase with ouabain blocks the binding of sodium to this higher affinity site. neither heat-denatured enzyme nor phospholipids extracted from the (na+, k+)-atpase contain a ouabain-inhibitable, higher affinity sodium ...	1976	133107
specificity of allogeneic and xenogeneic cell recognition in the fetal lamb.	cells prepared from liver, thymus, and spleen of fetal lambs at different stages if gestation were confronted with allogeneic and xenogeneic cells in mlc. specific elimination of the responding cells with budr and uv light together with a subsequent restimulation was used to study the specificity of the reaction. the response of fetal liver cells was not based on the existence of specifically recognizing cellular subpopulations; the response was concluded to be due either to stimulatory products ...	1976	133189
acute effect of nephrotoxic serum on renal sodium transport in the dog.	in order to study the tubular mechanism for salt retention in acute proliferative glomerulonephritis, clearance and micropuncture experiments were performed on nine volume-expanded dogs before and after injection of sheep anti-dog glomerular basement membrane (gbm) antibodies (nephrotoxic sera [nts]). histologic sections obtained two hours after nts injection following completion of the functional studies demonstrated infiltration of glomerular tufts by polymorphonuclear leukocytes, swelling of ...	1976	133267
quantitation of human t-lymphocytes in blood: use of automatic smearing instrument for preparing fixed slides of e-rosettes.		1976	133354
the experimental infection of specific pathogen free lambs with mycoplasma ovipneumoniae.	six colostrum-deprived spf lambs inoculated endobronchially with a second passage broth culture of a scottish strain of mycoplasma ovipneumoniae, were killed in batches of two at seven, 14 and 28 days post-inoculation. one lamb from each batch showed macroscopic and microscopic lung lesions similar to but milder than those described for respiratory mycoplasmoses in other species of animals and exhibited minor clinical symptoms. mycoplasma were recovered from all infected but from no control anim ...	1976	133436
[use of culture media with sheep serum for maintenance and isolation of leptospira strains].	a study was carried out on the effects of a culture medium prepared with sheep serum inactivated at 68 degrees c on leptospira cultures. good results were obtained showing that the medium with sheep serum can be used for the cultivation of leptospira in view of the preparation of antigens for microscopic agglutination and complement fixation. in experiments on the isolation of germs from organocultures and haemocultures the proportion of positive results obtained with sheep serum was smaller tha ...	1976	133448
fibrinogen-fibrin degradation products: hemagglutination inhibition immunoassay in plasma.	immunoassay for fibrinogen and/or fibrin degradation products (fdp) is generally in the clot and hence assay of serum may not reveal the true concentration of fdp in blood. we have developed a hemagglutination inhibition immunoassay for fdp in human plasma. d fragment appears to possess an antigenic determinant, called d-neoantigen, not found in native fibrinogen. rabbit antiserum produced against d fragment was absorbed with immunosorbent columns coupled with fibrinogen and normal human serum, ...	1975	133472
[specific prophylaxis of colibacillosis and salmonellosis in lambs and piglets].		1976	133510
[experience in the control of piroplasmosis in sheep].		1976	133511
[parasitocenosis in sheep].		1976	133512
[prevention of anoplocephaliasis in sheep].		1976	133513
[possible toxicity of phenothiazine].		1976	133514
[expedient times for utilizing ewe lambs].		1976	133516