Publications

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modeling host-seeking behavior of african malaria vector mosquitoes in the presence of long-lasting insecticidal nets.the efficiency of spatial repellents and long-lasting insecticide-treated nets (llins) is a key research topic in malaria control. insecticidal nets reduce the mosquito-human contact rate and simultaneously decrease mosquito populations. however, llins demonstrate dissimilar efficiency against different species of malaria mosquitoes. various factors have been proposed as an explanation, including differences in insecticide-induced mortality, flight characteristics, or persistence of attack. here ...201829031707
semi-field assessment of the bg-malaria trap for monitoring the african malaria vector, anopheles arabiensis.odour-baited technologies are increasingly considered for effective monitoring of mosquito populations and for the evaluation of vector control interventions. the bg-malaria trap (bgm), which is an upside-down variant of the widely used bg-sentinel trap (bgs), has been demonstrated to be effective to sample the brazilian malaria vector, anopheles darlingi. we evaluated the bgm as an improved method for sampling the african malaria vectors, anopheles arabiensis. experiments were conducted inside ...201729045484
multiple insecticide resistance in anopheles gambiae from tanzania: a major concern for malaria vector control.malaria vector control in tanzania is based on use of long-lasting insecticide treated nets (llins) and indoor residual spraying (irs), which both rely on the use of chemical insecticides. the effectiveness of these control tools is endangered by the development of insecticide resistance in the major malaria vectors. this study was carried out to monitor the susceptibility status of major malaria vectors to insecticides used for irs and llins in mainland tanzania.201729084560
indoor and outdoor malaria vector surveillance in western kenya: implications for better understanding of residual transmission.the widespread use of indoor-based malaria vector control interventions has been shown to alter the behaviour of vectors in africa. there is an increasing concern that such changes could sustain residual transmission. this study was conducted to assess vector species composition, feeding behaviour and their contribution to indoor and outdoor malaria transmission in western kenya.201729110670
insecticide resistance in anopheles arabiensis from ethiopia (2012-2016): a nationwide study for insecticide resistance monitoring.indoor residual spraying (irs) and long-lasting insecticidal nets (llins) remain the cornerstones of malaria vector control. however, the development of insecticide resistance and its implications for operational failure of preventative strategies are of concern. the aim of this study was to characterize insecticide resistance among anopheles arabiensis populations in ethiopia and describe temporal and spatial patterns of resistance between 2012 and 2016.201729151024
dissecting functional components of reproductive isolation among closely related sympatric species of the anopheles gambiae complex.explaining how and why reproductive isolation evolves and determining which forms of reproductive isolation have the largest impact on the process of population divergence are major goals in the study of speciation. by studying recent adaptive radiations in incompletely isolated taxa, it is possible to identify barriers involved at early divergence before other confounding barriers emerge after speciation is complete. sibling species of the anopheles gambiae complex offer opportunities to provid ...201729151864
zooprophylaxis as a control strategy for malaria caused by the vector anopheles arabiensis (diptera: culicidae): a systematic review.zooprophylaxis is the use of wild or domestic animals, which are not the reservoir host of a given disease, to divert the blood-seeking malaria vectors from human hosts. in this paper, we systematically reviewed zooprophylaxis to assess its efficacy as a malaria control strategy and to evaluate the possible methods of its application.201729157310
determination of the residual efficacy of carbamate and organophosphate insecticides used for indoor residual spraying for malaria control in ethiopia.indoor residual spraying is one of the key vector control interventions for malaria control in ethiopia. as malaria transmission is seasonal in most parts of ethiopia, a single round of spraying can usually provide effective protection against malaria, provided the insecticide remains effective over the entire malaria transmission season. this experiment was designed to evaluate the residual efficacy of bendiocarb, pirimiphos-methyl, and two doses of propoxur on four different wall surfaces (rou ...201729162113
new evidence of mating swarms of the malaria vector, anopheles arabiensis in tanzania.background: malaria mosquitoes form mating swarms around sunset, often at the same locations for months or years. unfortunately, studies of anopheles swarms are rare in east africa, the last recorded field observations in tanzania having been in 1983. methods: mosquito swarms were surveyed by trained volunteers between august-2016 and june-2017 in ulanga district, tanzania. identified anopheles swarms were sampled using sweep nets, and collected mosquitoes killed by refrigeration then identified ...201729184918
impact of insecticide resistance in anopheles arabiensis on malaria incidence and prevalence in sudan and the costs of mitigation.insecticide-based interventions have contributed to ∼78% of the reduction in the malaria burden in sub-saharan africa since 2000. insecticide resistance in malaria vectors could presage a catastrophic rebound in disease incidence and mortality. a major impediment to the implementation of insecticide resistance management strategies is that evidence of the impact of resistance on malaria disease burden is limited. a cluster randomized trial was conducted in sudan with pyrethroid-resistant and car ...201729229808
cost-effective larval diet mixtures for mass rearing of anopheles arabiensis patton (diptera: culicidae).larval nutrition, particularly diet quality, is a key driver in providing sufficient numbers of high quality mosquitoes for biological control strategies such as the sterile insect technique. the diet currently available to mass rear anopheles arabiensis, referred here to as the "iaea diet", is facing high costs and difficulties concerning the availability of the bovine liver powder component. to promote more affordable and sustainable mosquito production, the present study aimed to find alterna ...201729273056
photoperiodic responses of sahelian malaria mosquitoes anopheles coluzzii and an. arabiensis.throughout large parts of sub-saharan africa, seasonal malaria transmission follows mosquito density, approaching zero during the dry season and peaking during the wet season. the mechanisms by which malaria mosquitoes survive the long dry season, when no larval sites are available remain largely unknown, despite being long recognized as a critical target for vector control. previous work in the west african sahel has led to the hypothesis that anopheles coluzzii (formerly m-form anopheles gambi ...201729282150
the relative contribution of symptomatic and asymptomatic plasmodium vivax and plasmodium falciparum infections to the infectious reservoir in a low-endemic setting in ethiopia.the majority of p. vivax and p. falciparum infections in low-endemic settings are asymptomatic. the relative contribution to the infectious reservoir of these infections, often of low-parasite-density, compared to clinical malaria cases, is currently unknown but important for malaria elimination strategies.201829304258
status of insecticide resistance in malaria vectors in kwale county, coastal kenya.the strategy for malaria vector control in the context of reducing malaria morbidity and mortality has been the scale-up of long-lasting insecticidal nets to universal coverage and indoor residual spraying. this has led to significant decline in malaria transmission. however, these vector control strategies rely on insecticides which are threatened by insecticide resistance. in this study the status of pyrethroid resistance in malaria vectors and it's implication in malaria transmission at the k ...201829304805
evaluating efficacy of landsat-derived environmental covariates for predicting malaria distribution in rural villages of vhembe district, south africa.malaria in south africa is still a problem despite existing efforts to eradicate the disease. in the vhembe district municipality, malaria prevalence is still high, with a mean incidence rate of 328.2 per 100,0000 persons/year. this study aimed at evaluating environmental covariates, such as vegetation moisture and vegetation greenness, associated with malaria vector distribution for better predictability towards rapid and efficient disease management and control. the 2005 malaria incidence data ...201829330677
emerging pyrethroid resistance among anopheles arabiensis in kenya.vector control programs, particularly in the form of insecticide-treated bed nets (itns), are essential for achieving malaria elimination goals. recent reports of increasing knockdown resistance (kdr) mutation frequencies for anopheles arabiensis in western kenya heightens the concern on the future effectiveness of itns in kenya. we examined resistance in an. arabiensis populations across kenya through kdr mutations and world health organization-recommended bioassays. we detected two kdr alleles ...201829363447
an algal diet accelerates larval growth of anopheles gambiae (diptera: culicidae) and anopheles arabiensis (diptera: culicidae).the population sizes of anopheles gambiae giles (diptera: culicidae) and anopheles arabiensis patton (diptera: culicidae) increase dramatically with the onset of the rainy season in sub-saharan africa, but the ecological mechanisms underlying the increases are not well understood. as a first step toward to understand, we investigated the proliferation of algae, the major food of mosquito larvae, in artificial fresh water bodies exposed to sunlight for a short period, and old water bodies exposed ...201829365176
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