Publications

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synthesis and antimalarial evaluation of 9,10-dihydrophenanthrene amino alcohols. 19744608227
an experimental approach to the demonstration of a single generation of exo-erythrocytic schizonts in plasmodium berghei. 19744609378
erythropoietin production in virulent malaria.erythropoietin, the hormone responsible for stimulating erythrocyte production, was shown to increase significantly in the serum of mice during virulent malaria infection. although erythropoiesis was enhanced, it did not keep pace with the rate of erythocyte destruction; hence all plasmodium berghei-infected mice quickly succumbed to the deleterious consequences of severe uncompensated hemolytic anemia. since this apparently inadequate rate of erythropoiesis is not attributed to impaired erythro ...19744609912
in vitro ookinete development of the rodent malarial parasite, plasmodium berghei. 19744610107
babesia microti and plasmodium berghei yoelii infections in nude mice. 19744610411
host-cell specific proteolytic enzymes in plasmodium berghei infected erythrocytes. 19744610782
influence of allopurinol on the multiplication of rodent malaria parasites. 19744610931
comparison of the effects of neonatal thymectomy on plasmodium berghei, trypanosoma lewisi and trypanosoma cruzi infection in the albino rat. 19744611081
immunity to plasmodium berghei in rats: passive serum transfer and role of the spleen.pools of rat antiserum to plasmodium berghei had different levels of protective activity as assessed by a passive transfer test. preincubation of parasite inocula with an effective pool before injection did not significantly enhance protective activity. removal of the antiserum from preincubated parasite inocula abolished the bulk of protective activity. similarly, antiserum effective in intact animals was largely ineffective in splenectomized recipients. these experiments suggest a minimal role ...19744611920
plasmodium berghei ookinete formation in a nonvector cell line. 19744612127
malaria and the permeability of the host erythrocyte. 19744612377
[treatment of drug-resistant malaria: animal experiments]. 19744613506
ultrastructural studies on the early ookinete stage of plasmodium berghei nigeriensis and its transformation into an oocyst. 19744614723
acid hydrolases of the sporogonic stage of plasmodium berghei nigeriensis. 19744614726
the effect of plasmodium berghei and trypanosoma brucei infections on the immune expulsion of the nematode trichuris muris from mice. 19744615070
the uptake and incorporation of nucleosides into normal erythrocytes and erythrocytes containing plasmodium berghei. 19744615289
suppression of schistosome granuloma formation by malaria in mice.plasmodium berghei yeolii infection in mice suppressed granuloma formation around schistosoma mansoni eggs in the lungs. this suppressive effect was observed as early as 4 days after schistosome eggs were injected into malaria-infected mice and the maximum suppressive effect was seen by the 16th day. at this time granulomas in control mice than in mice infected with malaria. these data suggest that malaria has a direct influence on an immunologic reaction of the delayed hypersensitivity type. th ...19744615597
the selection of arylamidinourea antimalarials by their predicted physicochemical properties.1 a small group of arylamidinoureas for which the predicted physicochemical properties were widely spaced and uncorrelated was selected for study.2 the antimalarial activity of each compound was measured against three species of plasmodium. three corresponding regression equations were calculated relating the potency of each compound to its predicted physicochemical properties.3 the potency of further test compounds was forecast for each species, by using the corresponding regression equation. t ...19744615765
erythrocyte atp levels in mice infected with plasmodium berghei malaria. 19744617309
effect of hypothyroidism on parasitemia and survival in rodent malaria. 19744617503
development and decline of antiplasmodial indirect fluorescent antibodies in mice infected with plasmodium berghei (nk65) and treated with drugs.malaria parasites in mice present a simplified rodent model for the immunological study of malaria. experiments have been performed to determine the pattern and persistence of malaria antibody as detected by the indirect fluorescent antibody (ifa) test utilizing specific antimouse igm and igg conjugates. the antibody levels in mice inoculated with plasmodium berghei and treated with antimalarial drugs were traced after complete elimination of the parasites from the host. within 1-2 weeks after i ...19744617640
[immunological aspects of plasmodium berghei infections (action of cortisone in therapeutic doses)]. 19744618434
[evaluation of anti-plasmodium antibodies in idiopathic african splenomegaly]. 19744618790
modification by a latent contaminant of glomerular pathology in mice infected with plasmodium berghei.this study was designed to determine, by means of electron microscopy, the effect of latent contaminants-which are associated with the syringe passage of the parasite-on the findings in the glomeruli of p. berghei-infected mice. a rapid alteration of the glomerular basement membrane was observed in mice infected with the syringe-transmitted n strain, but not in those infected with the cyclically passaged nig strain. glomerular changes were also seen in mice inoculated with nonparasitized blood f ...19744619058
prevention of drug resistance in rodent malaria by the use of drug mixtures.development of resistance to chloroquine in rodent malaria is inhibited by giving this compound together with a potentiating mixture of pyrimethamine and sulfadoxine but this does not prevent the development of resistance to the last two compounds. the use of drug mixtures should be explored as a means of "protecting" chloroquine or new blood schizontocides intended for mass chemotherapy against human malaria. however, no general rule can be laid down without testing specific drug mixtures in lo ...19744619060
[research on congenital plasmodium berghei berghei malaria in mice. transplacental passage of the parasite and its evolution]. 19744619061
[characterization of the antigen produced by solubilization of cell membranes of plasmodium berghei]. 19744620172
[immunodepression vis-a-vis anti-whooping cough vaccine in mice infested with plasmodium berghei yoelii]. 19724620615
purification and characterization of phosphoenolpyruvate carboxylase from plasmodium berghei.phosphoenolpyruvate (pep) carboxylase was purified over 400-fold from plasmodium berghei. the purified enzyme was stable in 0.4 m potassium phosphate buffer (ph 7.4) containing 0.5 m glucose, 1 mm ethylenediaminetetraacetic acid (edta), and 1 mm mgcl(2). it had a molecular weight of 280,000 determined by sucrose density gradient centrifugation in this buffer, but it aggregated and was unstable in the presence of different salts or a more dilute solution of potassium phosphate. the k(m) for pep w ...19724621631
immunity to plasmodium berghei in rats: maximum levels of protective antibody activity are associated with eradication of the infection. 19724622015
demonstration of malarial antigens in the sera of plasmodium berghei-infected mice. 19724622282
[studies on the mechanism of action of a viral inducer of interferon in the protection of mice against massive infestation by endoerythrocytic forms of plasmodium berghei]. 19724624949
studies of splenomegaly in rodent malaria. 3. protein calorie malnutrition and splenomegaly in mice infected with plasmodium berghei yoelii. 19724625993
antibody and immunoglobulin synthesis in germfree and conventional mice infected with plasmodium berghei. 19724627628
lincomycin. 14. an improved synthesis and resolution of the antimalarial agent, 1'-demethyl-4'-depropyl-4'-(r)- and -(s)-pentylclindamycin hydrochloride (u-24, 729a). 19724629012
folic acid analogs. modifications in the benzene-ring region. 2. thiazole analogs. 19724629013
synthesis of some bis(2,4-diaminopyrimidines) and bis(2,4-diaminoquinazolines) as potential antimalarial agents. 19724629015
protective heterologous immunity between plasmodium atheruri and other plasmodium spp. and babesia spp. in mice. 19724629791
immunity to malaria and piroplasmosis in mice following low level infections with anthemosoma garnhami (piroplasmea: dactylosomidae). 19724629792
absence of immunity between trypanosoma musculi and intra-erythrocytic protozoa in mice. 19724629793
the challenge of drug-resistant malaria. 19734631761
infectivity of plasmodium berghei and of babesia rodhaini to various primates. 19734631764
folate antagonists. 9. 2,4-diamino-6-((aralkyl)alkylamino)quinazolines, a potent class of antimetabolites with prodigious antimalarial effects. 19724631920
second roundtable discussion on taxonomic problems relating to malaria parasites. 19734632261
2,4-diaminothieno(2,3-d)pyrimidines as antifolates and antimalarials. 1. synthesis of 2,4-diamino-5,6,7,8-tetrahydrothianaphthena(2,3-d)pyrimidines and related compounds. 19734632693
2,4-diaminothieno(2,3-d)pyrimidines as antifolates and antimalarials. 2. synthesis of 2,4-diaminopyrido(4',3':4,5)thieno(2,3-d)pyrimidines and 2,4-diamino-8h-thiopyrano(4',3':4,5)thieno(2,3-d)pyrimidines. 19734632694
2,4-diaminothieno(2,3-d)pyrimidines as antifolates and antimalarials. 3. synthesis of 5,6-disubstituted derivatives and related tetracyclic analogs. 19734632695
rigidity of red cell during malarial infection. 19734632768
[interferon and protection of the mouse against experimental infestation transmitted by the erythgrocytic forms of plasmodium berghei injected in massive doses. ii. effects of several immunosuppressive agents on protection patterns by a viral interferon inducer]. 19734771733
pathophysiological observations on blood of rats infected with plasmodium berghei. 19734800051
morphological effects of chloroquine on plasmodium berghei in mice. 19674861556
serological cross-reaction between rodent malaria parasites as determined by the indirect immunofluorescent technique.in view of the morphological similarity between the blood stages of plasmodium berghei berghei and p. b. yoelii on the one hand and p. vinckei and p. chabaudi on the other, these rodent malaria parasites were investigated by the indirect fluorescent antibody technique in the hope of thus differentiating between them.sera were obtained from rats hyperimmunized against these four parasites, from rabbits immunized against the soluble antigens of the blood stages of the parasites, and from a rabbit ...19674864305
[the importance of p-aminobenzoic acid to the course and immunity of malaria in animals (plasmodium berghei) and in man (pl. falciparum). ii. studies on naturally fed small children]. 19664866992
[the importance of p-aminobenzoic acid to the course and immunity of malaria in animals (plasmodium berghei) and in man (pl. falciparum). 3. studies on children experimentally fed on milk]. 19664866993
[changes in the dna content of spleen cells in vitro as a result of experimental malaria infection (plasmodium berghei)]. 19674877818
active immunization against malaria (plasmodium berghei). i. definition of antimalarial immunity. 19684878202
[nucleic acid metabolism in experimental malaria. 2. incorporation of adenosine and hypoxanthine into the nucleic acids of malaria parasites (plasmodium berghei and plasmodium vinckei)]. 19684878204
endotoxin-induced modification of plasmodium berghei infection in mice. 19694885402
aminoacyl transfer ribonucleic acid synthetases from cell-free extract of plasmodium berghei.aminoacyl transfer ribonucleic acid synthetases for leucine tyrosine, histidine, valine, proline, threonine, and lysine were obtainnned from cell-free extract of plasmodium berghei. the leucyl-trna synthetase cane charge trna from liver or escherichia coli with leucine-c(14), liver trna being a better substrate. the amount of aminoacylation increses linerly with respect to the quantity of trna added from either source and is dependent on the amount of enzyme added. the rate of aminoacylation is ...19694888104
[biologic cycle in the laboratory of plasmodium berghei killicki n. sub. sp]. 19684888201
plasmodium berghei infection in thymectomized rats. 19694893115
studies concerning the mechanism of action of antimalarial drugs. inhibition of the incorporation of adenosine-8-3h into nucleic acids of plasmodium berghei. 19694895016
further studies on the plasmodium berghei-anopheles stephensi--rodent system of mammalian malaria. 19684919047
propagation of plasmodium berghei and p. vinckei in mouse erythrocytes injected into chick embryos. 19704919090
[demonstration by fluorescent antibody technic of serum antibodies in white rats inoculated with plasmodium berghei]. 19694933046
immunologic enhancement in malaria infection (plasmodium berghei). 19714933405
studies of splenomegaly in rodent malaria. ii. the course of splenomegaly, igm, igg levels and igg immunofluorescent antibody titre in mice after infection with plasmodium berghei yoelii and-or plasmodium chabaudi. 19714938408
murine malaria. iv. disturbed immunological responsiveness during plasmodium berghei infection. 19714945431
[disk electrophoresis of 2 hydrosoluble extracts from plasmodia: plasmodium berghei (istisan strain) and plasmodium berghei (1967 vincke strain)]. 19714949667
location of chloroquine binding sites in plasmodium berghei. 19714950277
some biological properties associated with amino-oxy containing compounds. 19714950827
[intranuclear inclusion in the trophozoite of the erythrocytic form of plasmodium berghei in the rat by chloroquine absorption]. 19654954012
in vitro cultivation of erythrocytic forms of plasmodium knowlesi and plasmodium berghei. 19664957806
quantitative cytochemical study of erythrocytic stages of plasmodium lophurae plasmodium berghei. 19664957812
studies on the antigenic constituents of plasmodium berghei. i. immunologic analysis of the parasite constituents. ii. fractionation of the parasite constituents. 19664957820
effects of rat antiserum on the course of plasmodium berghei infection in mice. 19664957832
susceptibility to plasmodium berghei: parasitological biochemical and hematological studies in laboratory and wild mammals. 19664957835
plasmodium berghei infections in gnotobiotic mice and rats: parasitologic, immunologic and histopathologic observations. 19664957836
susceptibility of genetically standardized (jax) mouse strains to sporozoite- and blood-induced plasmodium berghei infections. 19664957839
morphologic observations on the effect of antimalarial agents on the erythrocytic forms of plasmodium berghei in vitro. 19664957850
immunodiffusion studies of plasmodium berghei: interactions of an extract of the erythrocytic forms with rabbit antisera. 19664960078
mode of action of chloroquine on plasmodium berghei and p. cynomolgi. 19674964195
preliminary studies of the antigenic structure of plasmodium berghei with the aid of diffusion in gel. 19684970214
[the multiplication rate of plasmodium berghei, plasmodium vinckei and babesia rodhaini]. 19674972587
[elimination of eperythrozoon coccoides from strains of babesia rodhaini, plasmodium berghei and plasmodium vinckei]. 19684974248
[modifications of the hypnotic activity of barbiturates in mice under impaludation with plasmodium berghei]. 19694978658
antiplasmodial precipitins demonstrated by double diffusion in agar gel in the serum of rats infected with plasmodium berghei. 19694978875
pam 1392 (2,4-diamino-6-(3,4-dichlorobenzylamino) quinazoline) as a chemotherapeutic agent: plasmodium berghei, p. cynomolgi, p. 19694983051
chemotherapy of plasmodium berghei. 19694983053
[antigenic qualities of plasmodium berghei]. 19694985635
apparent new modes of antimalarial action detected by inhibited incorporation of adenosine-8-3h into nucleic acids of plasmodium berghei. 19694987016
quantitative cytochemistry of malaria infected erythrocytes (plasmodium berghei, plasmodium chabaudi and plasmodium vinckei). 19694987018
amino acid activation for protein synthesis in plasmodium berghei. 19694987019
biogenesis of ribosomes in plasmodium berghei. 19694987020
malarial parasite metabolism: the metabolism of methionine by plasmodium berghei. 19694987021
lipid synthesis in vivo from 1-14c-oleic acid and 6-3h-glucose by intraerythrocytic plasmodium berghei. 19694987022
anemia in rats with equivalent splenomegalies induced by methyl cellulose and plasmodium berghei. 19694987026
characterization of protective antibodies produced in plasmodium berghei infected rats. 19694987032
cell-mediated immunity in rats infected with plasmodium berghei. 19694987033
aspects of immunity in mice inoculated with irradiated plasmodium berghei. 19694987034
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