Publications

[aseptic osteonecrosis of the femoral head in cancer patients with neuropathies caused by vincristine and vinblastine].	aseptic osteonecrosis has been described in many and dissimilar pathologic conditions--most frequently as the aftermath of fractures or dislocations; in falciform anemia, obesity, alcoholism; in diseases requiring constant and heavy corticosteroid therapy, and also following renal transplantation. many of these pathologies, especially alcoholism, diabetes, uremia, and collagen vascular diseases, have a common denominator: peripheral neuropathy, which is believed to be a pathogenetic factor suppo ...	2009	2756179
concomitant human infection due to rickettsia conorii and coxiella burnetii.		1989	2760493
the establishment of a clinical diagnostic method of the visual evoked potentials (veps) in the cat: the effects of recording electrode positions, stimulus intensity and the level of anesthesia.	the establishment of characteristic wave pattern of visual evoked potentials (veps) in the cat was attempted in order to be aid for clinical veterinary practitioners with the evaluation of visual dysfunction. 1) the position where the largest response of the veps was detected was close to the midline of the occipital area in normal cats. 2) the veps consisted of three components with latencies within 100 msec after flash stimulus. 3) flash stimuli of higher illumination produced veps of shorter ...	1989	2761147
[radiodiagnostic features of the pulmonary form of q fever].	patients with the pulmonary form of q fever and the more rarely described pleural reaction were presented. the purpose of this work was as follows: to pay attention to all characteristics of the radiological picture of the pulmonary form of q fever, to emphasize the importance of the radiological finding for the establishment of diagnosis, to point to the present possibilities of radiology and to put forward diagnostic procedures. namely, when managing the patients in clinical practice, radiolog ...	1989	2761477
c-terminal peptide alcohol, acid and amide analogs of desulfato hirudin54-65 as antithrombin agents.	analogs of the antithrombin peptide hirudin54-65 with c-terminal modifications have been synthesized in order to examine the requirements for alpha-thrombin inhibition. the c-terminal residue, gln65, could be replaced with l-amino acids or amino alcohols with neutral or charged hydrophilic side chains without greatly affecting the peptide's antithrombin potency as determined by inhibition of thrombin-induced clot formation in human plasma in vitro. derivatives with d- or l-amino carboxamides at ...	1989	2763270
effects of idebenone on memory impairment induced in ischemic and embolization models of cerebrovascular disturbance in rats.	two rat models of memory impairment in passive avoidance learning induced by cerebrovascular disturbance, were established to estimate the effects of a cerebral metabolic enhancer, idebenone. transient and global cerebral ischemia in rats, produced by 4-vessel occlusion for 200 s immediately after the acquisition trial of passive avoidance learning, shortened the latencies in the retention test trial performed 24 h later. this retrograde amnesia was reversed significantly by idebenone administer ...	1989	2764639
morphologic and morphometric studies on tumor necrosis produced by radiotherapy, and hyperthermia singly and in combination.	the purpose of the present study was to evaluate the therapeutic effects of hyperthermia associated with radiotherapy on neoplasia. two transplanted experimental tumors (undifferentiated carcinoma of mouse breast and sarcoma 37) were used. a protocol was followed that included, for both models, four groups of animals: 1) control group; 2) radiotherapy group; 3) hyperthermia group; 4) radiotherapy associated with hyperthermia group. the animals were sacrificed after therapy according to a differe ...	1989	2770309
[influence of electric stimulation of the medulla oblongata on the smooth muscle tone of the airway in cats].	changes in the tracheal smooth muscle tone have been studied in 30 cats anaesthetized with a chloralose-urethane mixture and paralyzed with succinyl choline bromide during electrical stimulation of the medulla oblongata. constrictor responses were evoked from the regions including the caudal portion of the dorsal motor nucleus of the vagus, nucleus ambiguous and neighbouring structures of the reticular formation. dilatory responses of the tracheal smooth muscle were observed during stimulation o ...	1989	2770913
[recurrent pericarditis with effusion caused by q fever. presentation of a case].	we present a case report of recurrent pericarditis with pericardial effusion and high levels of coxiella burnetti antibodies (phase ii), excluding other possible etiologies. the rarity of this disorder is commented and the necessity of be considered this etiological possibility in a second time, particularly in patients who are susceptible to suffer q-fever disease.	1989	2772370
[construction and testing of a strain gauge for measuring masticatory force].	the main objective of this study was to establish and test a measuring system for monitoring occlusal forces and force cycles during mastication. a measuring module using strain gauge transducers was incorporated in the bridge-pontic of a three part test bridgework. a load cell was used intraorally for loading and calibration. the test bridges were incorporated in the patient's mouth and calibrated in vivo using variable loads. the recording system was a special intensifying and processing syste ...	2009	2772595
severe disease in a dairy herd associated with acute infection with bovine virus diarrhoea virus, leptospira harjo and coxiella burnetii.	between november 1984 and february 1985, a serious outbreak of pyrexia, diarrhoea, agalactia, metritis and severe weight loss affected most of the recently calved cows in a 183-cow dairy herd in norfolk. fifteen cows died and 20 were culled. forty cows aborted during or after the outbreak, and many of them produced mummified fetuses; 18 calves were stillborn and three others died soon after birth. necropsy of three affected cows revealed ulceration of the gastrointestinal tract similar to that s ...	1989	2773203
[does q fever hepatitis mimic acute alcoholic hepatitis?].	the authors report the case of a chronic alcoholic woman, hospitalized for chest pain accompanied with fever. the laboratory test mimic an acute alcoholic hepatitis; the presence of a clinical and radiological pulmonary affection led to the discovery of q fever, the diagnosis of which was confirmed by serology and the discovery of a granuloma on histological examination of the liver.	1989	2774483
arthropathy of the wrist in leprosy--what changes are caused by long-standing peripheral nerve palsy?	a radiographical screening study of 338 leprotic patients was performed. clinically, according to a nerve score (ns) designed by us, 12.9% of 674 hands showed mild nerve palsy (ns 5 or 6), 75.9% moderate (ns 3 or 4), and 11.4% severe (ns less than 2). twenty-nine hands of 26 patients (ns 4.2 on average) demonstrated abnormal changes of the wrist joint on radiographs. we classified them into four groups: (a) lunate collapse (four patients), (b) scaphoid nonunion (eight), (c) scaphoid cyst (three) ...	2009	2774872
pericarditis associated with tick-borne q fever.	a case of pericarditis associated with q fever is described. transmission was probably via an arthropod vector, which was most likely the kangaroo tick amblyomma triguttatum. complete recovery occurred in association with the use of non-steroidal anti-inflammatory agents only. this is a rare presentation of q fever implicating transmission by a novel vector.	1989	2775046
the occurrence of hiv antibodies in drug addicts autopsied at the university institute of forensic medicine in copenhagen in 1987.	in 1987 a total of 89 intravenous drug addicts were admitted to medico-legal autopsy at the university institute of forensic medicine in copenhagen. totally 10 cases were reactive by the elisa test and five of these, or 7% of the total material tested, could be confirmed by the immuno-blotting test. the other five cases must be considered as false positive, possibly due to antibodies against cellular antigens. among the five real positive cases, four were known before-hand while in one case the ...	1989	2777161
repair of sublethal damage in two human tumor cell lines grown as multicellular spheroids.	multicellular tumor spheroids (mts) provide a suitable in vitro model to study radiation sensitivity of tumor cells. two cell lines of human origin, obtained from a neuroblastoma (nb-100) and a squamous cell carcinoma (hn-1), were exposed to graded doses (4-9 gy) of radiation with 18 mv photons. radiation was applied either as a single or as a split dose with an interval of 6 hr to determine the extent of sublethal damage repair. treated spheroids regrew at approximately the same growth rate as ...	1989	2777647
opening remarks of president fernando e. agrait on the occasion of the 50th anniversary of the cayo santiago macaque colony.		1989	2780954
[acute bronchiolitis in the adult and q fever].		1989	2781083
antibiotic susceptibilities of two coxiella burnetii isolates implicated in distinct clinical syndromes.	antibiotic susceptibility testing of two isolates of the q-fever agent, coxiella burnetii, was performed with recently and persistently infected l929 fibroblast cells. the two genetically distinct isolates, nine mile and priscilla, are implicated in two different clinical disease syndromes, acute and chronic q fever, respectively. we compared the efficacies of rifampin, doxycycline, and five 4-quinolone compounds (ciprofloxacin, difloxacin, ofloxacin, norfloxacin, and pefloxacin) in reducing per ...	1989	2782856
anti-inflammatory drugs from plant and marine sources.		2009	2784931
reversed left internal mammary artery graft for coronary bypass. evaluation of function with digital subtraction angiography and radionuclide imaging.	reversed left internal mammary artery grafting with retrograde flow to the left anterior descending coronary branch was used in five of 500 consecutive bypass operations. the indications were significant stenosis in the left subclavian artery (3 patients) or the proximal left internal mammary artery (1) and proximal damage to the left internal mammary artery during dissection from the thoracic wall (1). the postoperative clinical course was smooth in all five patients, with no evidence of myocar ...	2009	2786247
implantation of a gelatin-sponge as a model for effector recruitment. tumor growth inhibition by t-lymphocytes recovered from a site of tumor rejection.	nylon-wool-eluted lymphocytes, isolated from a site of tumor rejection in balb/c mice expressing concomitant tumor immunity, were examined for their ability to inhibit the growth of the emt6 tumor. tumor growth inhibition was monitored after co-inoculation of lymphocytes and tumor cells into naive mice in a winn-type adoptive-transfer assay. a pre-implanted gelatin sponge was employed to capture the tumor-infiltrating lymphocytes. mice harboring primary tumors were implanted 8 days later with ge ...	2009	2786457
human tonsillar dendritic cell-induced t cell responses: analysis of molecular mechanisms using monoclonal antibodies.	dendritic cells, isolated from human tonsillar tissue, were found to be potent stimulators of the sodium periodate t cell oxidative mitogenesis reaction. monoclonal antibodies against cd2, cd4, cd11a, cd18, lfa-3, icam-1, class i and class ii major histocompatibility complex (mhc) inhibited t cell proliferation in this response, whereas antibodies against cd8, cd11b, cd11c and cd16 had no effect. further, antibodies against cd2, cd11a, cd18, lfa-3 and icam-1 inhibited the early dendritic cell-t ...	1989	2786468
[outline of proliferative disorders in the mononuclear phagocytic system--clinicopathological aspects of histiocytosis x].		2009	2786580
[left ventricular pressure-volume diagram determined by forward and backward formatting of radionuclide ventriculography and analog pressure data].	pressure-volume (pv) loop is of great value for the assessment of left ventricular (lv) function, but its clinical application has been limited by methodological complexity. a new system was developed to make accurate loop with simplified procedure, and was applied to clinical and interventional study. the system constitutes of a mobile gamma camera, a poly-amplifier and a data processor (gms-550u, toshiba medical) installed in cardiac catheterization labo for simultaneous raw data handling and ...	2009	2786583
[single photon emission computed tomography by using n-isopropyl-p-[123i]-iodoamphetamine and 99mtc-hexamethyl propyleneamine oxime in a patient with herpes simplex encephalitis].	single photon emission computed tomographies (spects) by using n-isopropyl-p-[123i-imp]-iodo-amphetamine (123i-imp) and 99mtc-hexamethyl propyleneamine oxime (99mtc-hm-pao) were serially performed in a 70 yrs. old male with herpes simplex encephalitis (hse), and the chronological changes of accumulations were studied. accumulations of both 123i-imp and 99mtc-hm-pao increased initially, and then decreased with the stage of hse being advanced. the sequential appearance of the lesion in hse with 12 ...	2009	2786584
on suicide statistics.	the classical methodological problem of suicidology is reliability of official statistics. in this article, some recent contributions to the debate, particularly concerning the increased problem of suicide among inuit, are reviewed. secondly the suicide statistics of greenland are analyzed, with the conclusion that the official statistics, as published by the danish board of health, are generally reliable concerning greenland.	2009	2789569
chronic spontaneous tension pneumocephalus due to benign frontal sinus osteoma.	spontaneous pneumocephalus secondary to neoplasia is a rare condition. it may present with headaches, rhinorrhoea, otorrhoea, or meningitis in various combinations. a case of unusual presentation, with several months delay in diagnosis, with remarkable postoperative improvement is reported and the literature reviewed.	2009	2789724
[increased urinary excretion of neopterin in patients with graves-basedow disease].	in 12 patients with graves'-basedows' disease treated with carbimazole, the mean urinary neopterin, excretion (indicator of stimulation of cellular immunity) was 757.17 +/- 184.17 (95% confidence limit) mumol/mol creatinine with a range of 367-1420. in 12 healthy subjects of matching age and sex who served as controls the mean excretion was 422.0 +/- 96.38 (range 115 to 711, p less than 0.01). it cannot be ruled out that this increase is due to the immunomodulating action of carbimazole.	2009	2790883
[the polymerase chain reaction].		2010	2797295
early clinical results of the ttap acetabular cup.	one hundred seventy-five threaded titanium alloy prostheses (ttap) acetabular cups and 125 cemented cups were evaluated clinically and radiographically at 1 to 3 years postoperatively. the series was statistically different in that there were more women in the cemented group than in the non-cemented group (p less than .001). the cemented group was also older than the threaded group (p less than .001). pain, ambulation, function, range of motion, and roentgenograms were evaluated in all patients. ...	2009	2798250
early clinical results of the ttap acetabular cup.	one hundred seventy-five threaded titanium alloy prostheses (ttap) acetabular cups and 125 cemented cups were evaluated clinically and radiographically at 1 to 3 years postoperatively. the series was statistically different in that there were more women in the cemented group than in the non-cemented group (p less than .001). the cemented group was also older than the threaded group (p less than .001). pain, ambulation, function, range of motion, and roentgenograms were evaluated in all patients. ...	2009	2798250
non-suppurative bacterial arthritis diagnosed by fine-needle aspiration biopsy.		1989	2799306
[incidence of coxiella burnetti and chlamydia psittaci in cattle in southern bohemia].	in 1986 and 1987 in six districts and 22 localities of the southern bohemian region, and in one district and one locality of the western bohemian region the total of 747 head of cattle was examined by a microagglutination method (mar) and complement fixation method (kfr) for antibodies to coxiella burnetii and chlamydia psittaci. the positivity of c. burnetii detection was 44.4% in mar and 16.5% in kfr. the positivity of chl. psittaci detection was 7.1%. the widespread incidence and highly posit ...	1989	2800248
[diabetic autonomic neuropathy].	affection of the vegetative nervous system is a relatively frequent and often serious complication of diabetes. the aetiopathogenesis of diabetic autonomous neuropathy has not been reliably explained so far, most probably metabolic changes are involved resulting from prolonged hyperglycaemia. a part played by other e.g. congenital factors cannot be ruled out. autonomous neuropathy can influence the function of the cardiovascular, digestive, urogenital and other systems and cause difficult diagno ...	2009	2800365
[current emergency treatment of lesions of the flexor tendons: anatomical, biomechanical and cicatricial aspects].	emergency treatment of flexor tendon lesion in 1988: anatomic biomechanical and healing characteristics. flexor tendon surgery in 1988 must take into account detailed anatomic knowledge as well as healing and biomechanical properties of flexor tendons. application of standardised surgical technics allows reliable treatment when the surgeon is familiar with these technics and the basic knowledge they suppose. the authors detail the technics and certain details with practical goals.	2009	2800845
q fever urban cases in romania.	q fever urban sporadic cases in romania in the 1981-87 period are reviewed as concerns their incidence, seasonality and epidemiological data. urban cases represented 76.8% as against 23.2% rural cases from the 134 q fever sporadic cases detected in this period. cases were distributed throughout all months with peaks during april (18.4% of cases) and june (19.4%). infections were not related to contact with livestock or domestic birds or with raw milk drinking. cases could not be identified as q ...	1989	2802967
[magnetic resonance imaging of lumbosacral lipomas in infants].	magnetic resonance imaging (mri) was conducted on infants with lumbosacral lipomas. based on chapman's classification (1982), these mris were classified into three representative types: caudal, dorsal and transitional. as confirmed by intraoperative observations, the relation between the lipomas and the spinal cord was clearly disclosed in the preoperative mri. however, in the dorsal type, the intraoperative view of the margin between the lipomas and spinal cord was different from the mri findin ...	2009	2803809
[response to haloperidol and analysis of growth curve in hereditary progressive dystonia with marked diurnal fluctuation].	a case of 10-year-old female with hereditary progressive dystonia with marked diurnal fluctuation (hpd) was described. her development was normal. then at the age of eight, she developed dystonia of the left lower extremity that became noticeable toward evening but subsided after taking sleep. and the velocity of height gain decreased at the age of nine (from 5 cm to 3.6 cm per year). before the diagnosis of hpd, small doses of haloperidol (0.015 mg/kg/day) were given to her. thereafter she deve ...	2009	2803813
steroidogenesis in liposomal system containing adrenal microsomal cytochrome p-450 electron transfer components.	purified adrenal microsomal p-450c21 and/or p-45017 alpha,lyase were incorporated with purified nadph-cytochrome-p-450 reductase into liposome membranes composed of phosphatidylcholine, phosphatidylethanolamine and phosphatidylserine at a molar ratio of 5:3:1. the rate dependences of reduction of liposomal p-450c21 in the fast phase as well as progesterone hydroxylation activities of p-450c21 and p-45017 alpha,lyase on the reductase concentration in the liposome membranes suggested that electron ...	1989	2804111
cardiac transplant recipients with preoperative pulmonary hypertension. evolution of pulmonary hemodynamics and surgical options.	among 48 consecutive patients with pretransplant pulmonary vascular resistance (pvr) greater than 4 wood units, 38 patients underwent orthotopic heart replacement (oht), and the remaining 10 received a graft in a heterotopic position (hht). the oht recipients were smaller (63 vs. 73 kg, p less than 0.05) and received a larger donor heart (donor-recipient, 109% vs. 79%, p less than 0.001) with a shorter graft ischemic time (108 vs. 139 minutes, p less than 0.05) than hht recipients, reflecting pa ...	2009	2805309
cardiac transplant recipients with preoperative pulmonary hypertension. evolution of pulmonary hemodynamics and surgical options.	among 48 consecutive patients with pretransplant pulmonary vascular resistance (pvr) greater than 4 wood units, 38 patients underwent orthotopic heart replacement (oht), and the remaining 10 received a graft in a heterotopic position (hht). the oht recipients were smaller (63 vs. 73 kg, p less than 0.05) and received a larger donor heart (donor-recipient, 109% vs. 79%, p less than 0.001) with a shorter graft ischemic time (108 vs. 139 minutes, p less than 0.05) than hht recipients, reflecting pa ...	2009	2805309
[differentiated changes in the activity of the sympathetic nerves induced by glycopenia in spontaneously hypertensive rats].	2-deoxy-d-glucose (2-dg) evokes an increase in the efferent discharge rate of the adrenal nerve in anesthetized rats and rabbits. a 63% increase in adrenal sympathetic nerve activity (adrsna) occurred within 15 min after 125 mg/kg 2-dg administration in alert animals, no changes being revealed in the renal sympathetic nerve activity (rensna), blood pressure (bp) or the heart rate (hr). additional administration of 375 mg/kg 2-dg (cumulative dose 500 mg/kg) led to an over 120% increase in the adr ...	1989	2806664
endotoxicosis induced by coxiella burnetii lipopolysaccharide stimulates a ribosomal protein s6 kinase: some properties of the partially purified enzyme.	guinea pig endotoxicosis induced by lipopolysaccharide from coxiella burnetii nine mile phase i stimulates phosphorylation of liver ribosomal protein s6, with a 50% increase at 12 h postinoculation. the responsible protein kinase (s6pk) has been partially purified from liver; its activity is independent of cyclic amp and of ca2+ plus phosphatidyl serine or diacylglycerol. the preparation has an apparent optimum concentration of 20 mm mg2+, while ca2+ and mn2+ are each inhibitory at 2 mm. the app ...	1989	2807543
insulin-like growth factor i (igf-i) and body growth. physiological implications and clinical applications.		2010	2809085
progressive demyelinating disease following acute q fever.	we describe the case of a 36-year-old farmer who presented with an acute febrile illness, diagnosed on serological testing as acute q fever. he then developed progressive demyelinating disease. the relationship between acute q fever and subsequent demyelinating disease is discussed.	1989	2809237
[oral administration of ok-432 (picibanil). (8th report) clinical application: its immunomodulatory effects on the patients with gastrointestinal cancers].	a streptococcal preparation, ok-432 at a dose of 5 ke was orally administered to the patients with gastric or colorectal cancer for 7 approximately 14 days before operation, and its immunomodulatory effects on peripheral blood lymphocytes (pbl), regional lymph node lymphocytes (rlnl) and tumor infiltrating lymphocytes (til) were assessed. ok-432 treated group included 5 gastric and 6 colorectal cancers, and control group included 6 gastric and 8 colorectal cancers. after oral administration of o ...	1998	2809385
role of adenosine in the gastric blood flow response to pentagastrin in the rat.	we tested the hypothesis that the increase in gastric mucosal blood flow during pentagastrin-stimulated acid secretion in the rat is mediated partly by endogenously generated adenosine. in in vivo microscopic studies, topical 10(-5) to 10(-3) m adenosine dose-dependently dilated the submucosal arterioles, the vessels that control mucosal blood flow. the adenosine receptor antagonist 8-phenyltheophylline, significantly reduced adenosine's vasodilatory response. an adenosine analog with a high a2 ...	1989	2810111
role of adenosine in the gastric blood flow response to pentagastrin in the rat.	we tested the hypothesis that the increase in gastric mucosal blood flow during pentagastrin-stimulated acid secretion in the rat is mediated partly by endogenously generated adenosine. in in vivo microscopic studies, topical 10(-5) to 10(-3) m adenosine dose-dependently dilated the submucosal arterioles, the vessels that control mucosal blood flow. the adenosine receptor antagonist 8-phenyltheophylline, significantly reduced adenosine's vasodilatory response. an adenosine analog with a high a2 ...	1989	2810111
effects of cisapride on isolated guinea pig colon.	effects of cisapride were studied on the whole segments and muscle strips isolated from the guinea pig ascending colon. in whole segment preparations, external application of cisapride (0.4-10 microm) produced relaxation and inhibited spontaneous and evoked intraluminal pressure changes. intraluminal application (1-10 microm) increased the pressure response. in many circular muscle strips (18 preparations out of 20), cisapride (0.3-1 microm) increased the mechanical activity, particularly when t ...	1989	2810941
[complications at home following anesthesia in day surgery].		2009	2812082
[complications at home following anesthesia in day surgery].		2009	2812082
serological evidence of q fever in cattle in malawi.	the serological prevalence of coxiella burnetii in cattle in malawi is unknown. serum samples from 200 malawian zebu cattle were tested for c. burnetii antibodies using the complement fixation test. the percentage of positive and suspicious titres was 1.5% and 5% respectively.	1989	2812706
lipid and lipoprotein measurements in a normal, adult cuban population.	an attempt was made to determine the normal reference values of lipid- and lipoprotein levels (cholesterol), triglycerides, cholesterol in high- and low-density lipoproteins) in a selected, apparently healthy, cuban population. results were expressed as mean, and various percentiles of measured values; two ratios: risk 1 (ldl-c/hdl-c) and risk 2 (tc/hdl-c) were also calculated. approximately 40% of the subjects aged 20 to 30 years had cholesterol values above 200 mg/dl. females had significantly ...	2009	2812958
lipid and lipoprotein measurements in a normal, adult cuban population.	an attempt was made to determine the normal reference values of lipid- and lipoprotein levels (cholesterol), triglycerides, cholesterol in high- and low-density lipoproteins) in a selected, apparently healthy, cuban population. results were expressed as mean, and various percentiles of measured values; two ratios: risk 1 (ldl-c/hdl-c) and risk 2 (tc/hdl-c) were also calculated. approximately 40% of the subjects aged 20 to 30 years had cholesterol values above 200 mg/dl. females had significantly ...	2009	2812958
[familial infantile nephrotic syndrome with ocular abnormalities].	two siblings born from consanguineous parents experienced infantile nephrotic syndrome with ocular and neurological abnormalities and a micropenis in the boy; both patients died before age 1. the opportunity to perform successively a renal biopsy and a two-step binephrectomy permitted a good histological follow-up. the lesions were characterized by mesangial involvement, followed by an extensive extracapillary proliferation and tubular dilatations with a high mitotic activity of the epithelium w ...	2009	2812971
[familial infantile nephrotic syndrome with ocular abnormalities].	two siblings born from consanguineous parents experienced infantile nephrotic syndrome with ocular and neurological abnormalities and a micropenis in the boy; both patients died before age 1. the opportunity to perform successively a renal biopsy and a two-step binephrectomy permitted a good histological follow-up. the lesions were characterized by mesangial involvement, followed by an extensive extracapillary proliferation and tubular dilatations with a high mitotic activity of the epithelium w ...	2009	2812971
coxiella burnetii infection in prosthetic devices.		1989	2814166
isolation of haemophilus somnus from bovine milk.		1989	2815520
urolith analysis.		1989	2815527
urolith analysis.		1989	2815527
[functional paraganglioma (pheochromocytoma) in an aortico-pulmonary location].		2009	2815638
[functional paraganglioma (pheochromocytoma) in an aortico-pulmonary location].		2009	2815638
[what is your diagnosis? notalgia paresthetica].		2010	2817692
interstitial deletion of (17)(p11.2). a microdeletion syndrome. another example.	another example of del (17)(p11.2) in a 3-year-old boy with psychomotor retardation, broad face, midface hypoplasia, prognathism, and behavioural anomalies was diagnosed clinically and confirmed by prometaphase analysis. it seems that this new microdeletion syndrome may not be so rare.	1989	2817780
similarities and differences in the regulation of hepatic cytochrome p-450 enzymes by diabetes and fasting in male rats.	the effects of streptozotocin-induced diabetes and fasting on hepatic cytochrome p-450 enzymes in sexually mature male rats were studied by immunochemical techniques and enzyme assays. the level of cytochrome p-450ac (an acetone/ethanol inducible form), 65 pmol/mg microsomal protein in control rats, increased 4- to 5-fold in diabetic rats and 3- and 5-fold in fasting rats. in contrast, p-450 ut-a (a male specific form) decreased drastically from 295 pmol/mg in the control group to about 10% of t ...	1989	2818618
xanthogranulomatous pyelonephritis.	xanthogranulomatous pyelonephritis is a rare chronic form of pyelonephritis with a clinical presentation often suggestive of a renal mass. we present 51 patients with histologically proven xanthogranulomatous pyelonephritis who were treated by nephrectomy. the results are discussed and compared with those from the literature.	2009	2819382
'ring' granulomas in cytomegalovirus hepatitis.	a liver biopsy specimen obtained from a patient with cytomegalovirus hepatitis demonstrated "ring" granulomas similar to those previously described as characteristic of acute coxiella burnetii infection. q fever is not the only infectious disease in which fibrinoid rings may form within granulomatous foci.	1987	2820347
wilms tumors: relationship of nuclear deoxyribonucleic acid ploidy to patient survival.	nuclear deoxyribonucleic acid ploidy studies with paraffin-embedded archival tumor specimens were performed by flow cytometry on extracted nuclei from 56 wilms tumors. before the era of chemotherapy 9 patients had a 33 per cent survival rate at 5 years. no significant correlation between deoxyribonucleic acid ploidy pattern and survival was seen in this early group of patients. since 1960, 47 patients underwent radical nephrectomy and received chemotherapy. deoxyribonucleic acid histograms in th ...	2010	2821294
synapse formation in the olfactory cortex by regenerating optic axons: ultrastructural evidence for polyspecific chemoaffinity.	the optic nerve was severed at its entry into the optic chiasma and implanted into the striatal region of the ipsilateral cerebral hemisphere in adult frogs (rana pipiens). regenerating retinal ganglion cell axons, observed by the autoradiographic tracing method and by horseradish peroxidase (hrp) fiber filling, grew anteriorly along the olfactory tracts and posteriorly along the ipsilateral lateral forebrain bundle and stria medullaris. many of the regenerating axons ultimately joined the ipsil ...	2010	2822778
[mesoblastic nephroma].	three cases of the "cellular" variant of mesoblastic nephroma are reported. a feature of one of them was prolonged (7.5 months) spontaneous development of the tumor which presented a peculiar morphologic appearance. diagnostic differentiation of mesoblastic nephroma from wilm's tumor and sarcomas is discussed. results of an electron-microscopic study of one of the tumors are given.	2010	2823749
in vivo pharmacology of ici 198,615: a novel, potent and selective peptide leukotriene antagonist.	the in vivo pharmacology of ici 198,615, a highly potent and selective peptide leukotriene (lt) receptor antagonist, is described. in a conscious guinea pig model, ici 198,615 provided dose-related antagonism of aerosol ltd4-induced dyspnea when administered p.o., i.v. or by aerosol. the pharmacologic half-lives of ici 198,615 by these routes of administration were greater than 16 hr, 68 min and 34 min, respectively. in pulmonary mechanics studies in which the effects of i.v. or aerosol administ ...	1987	2824752
paraventricular nucleus lesion prevents yawning and penile erection induced by apomorphine and oxytocin but not by acth in rats.	the effect of electrolytic lesion of the paraventricular nucleus of the hypothalamus (pvn) on yawning and penile erection induced by apomorphine, oxytocin and adrenocorticotropic hormone (acth1-24) was studied in male rats. in sham-operated rats, apomorphine (50 micrograms/kg s.c.), oxytocin (30 ng i.c.v.), and acth1-24 (10 micrograms i.c.v.) significantly increased the number of yawning and penile erection episodes. in pvn-lesioned rats, apomorphine- and oxytocin-, but not acth-induced response ...	1987	2825910
role of the autonomic nervous system, renin-angiotensin system, and arginine vasopressin during the onset and maintenance of acth hypertension in sheep.	the roles of the autonomic nervous system, renin-angiotensin system, and arginine vasopressin (avp) during the onset of acth-induced hypertension were investigated in conscious sheep. autonomic ganglion blockade or combined adrenergic and cholinergic receptor blockade demonstrated that an intact sympathetic nervous system was not essential for the development or maintenance of the hypertension. autonomic blockade augmented the pressor response to acth, indicating that baroreceptor-mediated refle ...	1987	2825944
role of the autonomic nervous system, renin-angiotensin system, and arginine vasopressin during the onset and maintenance of acth hypertension in sheep.	the roles of the autonomic nervous system, renin-angiotensin system, and arginine vasopressin (avp) during the onset of acth-induced hypertension were investigated in conscious sheep. autonomic ganglion blockade or combined adrenergic and cholinergic receptor blockade demonstrated that an intact sympathetic nervous system was not essential for the development or maintenance of the hypertension. autonomic blockade augmented the pressor response to acth, indicating that baroreceptor-mediated refle ...	1987	2825944
[transthoracic aspiration biopsy in the diagnosis of peripheral pulmonary neoplasms].		2009	2826965
reduction of inositol triphosphate in retinal microvessels by glucose and restimulation by myo-inositol.	the formation of inositol phospholipids (ipls) and inositol phosphate esters (ipes) in response to glucose was studied in isolated retinal microvessels from porcine eyes. retinal microvessels incubated from 60 hr with myo-[3h]inositol were sequentially extracted to obtain ipls and ipes. [3h]inositol-labelled ipls were deacylated to produce the corresponding glycero derivatives. both deacylation products and water-soluble ipes were monitored by anion-exchange chromatography. in the presence of hi ...	1987	2828091
activation of the renin angiotensin system in short aortic cross-clamp times.		1988	2831013
serological investigations for some bacterial and viral pathogens in fallow deer (cervus dama) and wild boar (sus scrofa) of the san rossore preserve, tuscany, italy.	sera of 43 fallow deer (cervus dama) of the san rossore preserve (tuscany, italy) were examined for antibodies against eight pathogens; one proved positive for brucella sp., 21 for listeria monocytogenes, 34 for chlamydia psittaci, three for coxiella burnetii, one for infectious bovine rhinotracheitis virus, 11 for parainfluenza-3 virus, 25 for bovine viral diarrhea virus and six for bovine respiratory syncytial virus. no age and sex difference in the positivity rates and titers was evidenced, w ...	1988	2832622
viruses in sewage waters during and after a poliomyelitis outbreak and subsequent nationwide oral poliovirus vaccination campaign in finland.	during an outbreak of paralytic poliomyelitis in finland in 1984 and 1985 the widespread circulation of the causative wild-type serotype 3 poliovirus in the population was documented by demonstrating the virus in sewage water specimens in 13 different locations in the greater helsinki district and in 13 other cities or towns all over the country. after the nationwide campaign with oral poliovirus vaccine in 1985, poliovirus serotypes 2 and 3 were readily isolated from sewage waters for up to 2 m ...	1988	2833160
two mutant alleles of the insulin receptor gene in a patient with extreme insulin resistance.	insulin receptor complementary dna has been cloned from an insulin-resistant patient with leprechaunism whose receptors exhibited multiple abnormalities in insulin binding. the patient is a compound heterozygote, having inherited two different mutant alleles of the insulin receptor gene. one allele contains a missense mutation encoding the substitution of glutamic acid for lysine at position 460 in the alpha subunit of the receptor. the second allele has a nonsense mutation causing premature cha ...	1988	2834824
two mutant alleles of the insulin receptor gene in a patient with extreme insulin resistance.	insulin receptor complementary dna has been cloned from an insulin-resistant patient with leprechaunism whose receptors exhibited multiple abnormalities in insulin binding. the patient is a compound heterozygote, having inherited two different mutant alleles of the insulin receptor gene. one allele contains a missense mutation encoding the substitution of glutamic acid for lysine at position 460 in the alpha subunit of the receptor. the second allele has a nonsense mutation causing premature cha ...	1988	2834824
epstein-barr virus infection and hepatic fibrin-ring granulomas.	hepatic fibrin-ring granulomas were the main histological finding in the liver of a 38-year-old man with epstein-barr virus primary infection. the patient presented with fever, hepatomegaly, icterus, abnormal liver tests, autoimmune hemolytic anemia, and mononucleosis syndrome. there was neither enanthema nor lymphadenopathy or splenomegaly. serologic tests disclosed an epstein-barr primary infection profile: anti-viral capsid antigen igm antibodies and anti-early antigen antibodies were present ...	1988	2836298
suspected superphosphate poisoning in calves.		1987	2838010
inhibition of phagocytosis and interleukin-1 production in pulmonary macrophages from rats with sialodacryoadenitis virus infection.	to test whether or not sialodacryoadenitis virus (sdav) infection in rats affects pulmonary macrophage function, we intranasally inoculated pathogen-free f344 rats with sdav and collected alveolar and interstitial macrophages 5 d later. we assessed fc receptor-mediated attachment and phagocytosis by phase-contrast microscopic examination of monolayers of alveolar and interstitial macrophages incubated with zymosan, nonopsonized sheep erythrocytes, or erythrocytes opsonized with rabbit antisheep- ...	1988	2841399
[experimental study on liver cancer--effect of intra-arterial injection of adriamycin-lipiodol emulsion on vx2 liver tumor].		1988	2846718
camp-mediated growth inhibition of a b-lymphoid precursor cell line reh is associated with an early transient delay in g2/m, followed by an accumulation of cells in g1.	this study was undertaken to gain more insight into the effects of cyclic adenosine monophosphate (camp) on cell-cycle progression in the b-lymphoid precursor cell line reh. the adenylate cyclase activator forskolin reduced the proliferation of asynchronously growing reh cells by 50% after 72 hr culture. growth inhibition was associated with an accumulation of cells in g1. furthermore, we demonstrated that forskolin provoked a delay of cells for approximately 10 hr in g2/m prior to the g1 arrest ...	2010	2848044
norepinephrine and gtp-gamma-s increase myofilament ca2+ sensitivity in alpha-toxin permeabilized arterial smooth muscle.	a new method for preparing permeabilized smooth muscle fibers from rabbit mesenteric artery has been developed using alpha-toxin, a transmembrane pore-making exo-protein produced by staphylococcus aureus. after alpha-toxin treatment the fibers developed tension as a function of ca2+ concentration (ec50 = 890 nm). but they could not contract without added atp, indicating atp is permeable. when the sarcoplasmic reticulum was loaded with 5 x 10(-7) m ca2+ solution, ne induced a transient contractio ...	1988	2849434
three-dimensional structure of renal na,k-atpase determined from two-dimensional membrane crystals of the p1 form.	electron microscopy and image processing were used to reconstruct a three-dimensional model of membrane-bound monomeric renal na,k-atpase from negatively stained two-dimensional crystals of the p1 type. correlation methods were applied to obtain projection averages which were aligned by a phase difference minimization procedure. the self-consistency of the reconstruction process was high as determined by correlation between experimental projections and projections of the calculated model. the th ...	1988	2850317
clinical use of the somatostatin analog sms 201-995 in endocrinology.		2009	2852695
sulphadiazine desensitisation in aids patients.		2009	2857234
holy dread.		2009	2857242
when is discontinuation of dialysis justified?	the staff of a renal dialysis unit in oxford, england, determined that further treatment would no longer be beneficial to a mentally handicapped patient who was noncompliant and disruptive. the director of the hostel where the patient lived disputed the unit's assessment of the patient and contacted the british kidney patient association, which assumed payment for private care with intent to bill the health authority. articles have appeared in the press, and government authorities have been aske ...	2009	2857261
use of ether in life-threatening acute severe asthma.	two patients with acute severe asthma who had failed to improve with conventional treatment, mechanical ventilation, and halothane showed prompt bronchodilator response following administration of diethyl ether by inhalation. airway pressures fell, and there was a dramatic improvement in blood gas analysis and clinical condition.	2007	2857266
severe central-nervous-system toxicity associated with cyclosporin.		2007	2857289
the smoking gun.		2010	2857863
mosquito breeding in water meter chambers.		2010	2863184
characterization of enhanced intestinal permeability; electrophysiological study on the effects of diclofenac and ethylenediaminetetraacetic acid.	the mechanism of the enhancing effects of diclofenac sodium and disodium ethylenediaminetetraacetate (edta) on intestinal permeability to sulphanilic acid were investigated in the rat isolated jejunum by an electrophysiological technique. the results suggested that diclofenac sodium increased the mucosal-to-serosal flux rate of sulphanilic acid by enhancing both transcellular and paracellular permeabilities while the effect of edta was located only in the paracellular pathway.	1985	2863363
[etage fracture].		2010	2863427
therapeutic drug monitoring.		2010	2863512