Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| the effects of amiodarone on serum thyroid hormones and hepatic thyroxine 5'-monodeiodination in rats. | amiodarone (2-n-butyl-3,4'-diethylaminoethoxy-3', 5'-diiodobenzoyl-benzofurane) is an antiarrhythmic drug which increases serum t4 and rt3 levels in patients and lowers serum t3 levels. to investigate its effects on t4 metabolism and its cardiac action, we fed amiodarone to male fisher rats at doses of 5, 15, and 45 mg/kg bw x day; controls received potassium iodide for 4-7 weeks, and another group received sodium ipodate. at 4 weeks, amiodarone caused a dose-dependent increase in the serum t4 c ... | 1983 | 6617581 |
| rebound phenomenon observed during the compaction of samples in the fisher subsieve sizer for measuring specific surface area of griseofulvin. | 1983 | 6620162 | |
| estimating length density and quantifying anisotropy in skeletal muscle capillaries. | the accurate estimation of stereological parameters defined on anisotropic structures is a long-standing problem. in this paper we seek to estimate the capillary length density jv in skeletal muscle tissue. a well-known model for directional anisotropy in space, namely the 'spherical normal' or 'fisher axial distribution' model, is found to fit the relevant data satisfactorily. based on this model, a short-cut estimation method is proposed and illustrated with a numerical example. this method es ... | 1983 | 6620361 |
| morphometric features as tribal predictors in north-western amazonia. | multivariate analyses of variance were carried out on stature and weight of 50 adults (25 males, 25 females) from each of two linguistically distinct groups, maku and tukanoan, living sympatrically in north-western amazonia. results showed significant intertribal differences, with maku (sylvan hunter-gatherers) being both shorter and lighter than their tukanoan (riparian fisher-gardeners) conspecifics. classification with a linear discrimination function achieved 80% accuracy. stature or weight ... | 2006 | 6638939 |
| heritability of body measurements among the jalari population in visakhapatnam. | a total of 436 jalari families, a fishing caste population of visakhapatnam in andhra pradesh, india, are surveyed for thirteen anthropometric measurements. heritability coefficients (h2) of these anthropometric measurements are calculated using fisher (1918) and penrose (1971) formulae. the longitudinal measurements record highest heritability coefficients followed by breadth measurements and circumferences. the heritability coefficients of all the measurements, calculated by using penrose's me ... | 2007 | 6638944 |
| the effect of indomethacin on the growth of epidermoid carcinoma of the palate in rats. | the in vivo effect of indomethacin therapy in head and neck cancer was tested using rats (fisher 344) with implanted epithelial palatal carcinoma. indomethacin was then given to half of the rats in their drinking water, starting two weeks after tumor implantation. the animals were then killed at four weeks and the tumor volumes were measured. it was found that four (21%) of the 19 rats were complete responders and eight (42%) of the 19 rats were partial responders. the control group showed incre ... | 1983 | 6639438 |
| an estimate of capillary anisotropy and determination of surface and volume densities of capillaries in skeletal muscles of the conger eel (conger conger l.). | fast and slow muscle fibres were isolated from the axial muscles of conger eel (conger conger l.) and examined by electron microscopy. volume densities of mitochondria, vv (mit, f); intracellular lipid stores, vv (lip, f); and myofibrils, vv (mf, f) were respectively 0.23, 0.18, 0.47 for slow and 0.03, 0.002, 0.79 for fast fibres. factors affecting the representative sampling of capillary supply were investigated using semi-thin (0.5 micron) sections. an estimate of the degree of capillary aniso ... | 1983 | 6647737 |
| brainstem encephalitis or the miller fisher syndrome--a variant of acute idiopathic polyneuropathy. case reports. | a syndrome comprising ophthalmoplegia, ataxia and areflexia was described by miller fisher in 1956. while some consider it to be a benign variety of acute idiopathic (guillain-barré) polyneuropathy, there are reports of the need for ventilatory support and of the benefits of plasmapheresis. two further cases are described. the first patient was seen in 1972 and was well 10 years later. the second patient gave cause for concern and might have benefitted from plasmapheresis, but nevertheless he re ... | 1983 | 6648744 |
| surnames in sardinia. i. fit of frequency distributions for neutral alleles and genetic population structure. | distributions of surnames were examined using data from about 40 000 individuals from consanguineous marriages (1930-59) in the island of sardinia. they fit the karlin-mcgregor (1967) distribution for neutral alleles. the logarithmic distribution by fisher (1943) and the karlin-mcgregor (1967) distribution give practically indistinguishable fits to these data. the two parameters underlying the fisher distribution, alpha and nu, are fully interdependent, given the sample size n. from the latter a ... | 1983 | 6651221 |
| intraaortic balloon pump morbidity: a comparative analysis of risk factors between percutaneous and surgical techniques. | we reviewed our concurrent experience with percutaneous insertion versus surgical placement of the intraaortic balloon pump over a two-year period both to compare morbidity and to provide guidelines for the choice of method in particular patient groups and clinical settings. the effects on morbidity of sex, age, emergency placement, coexisting peripheral vascular disease, and duration of counterpulsation were determined. sex was a highly significant factor, with low complication rates (3/29 or 1 ... | 1983 | 6651378 |
| functional brain tissue transplantation: reversal of lesion-induced rotation by intraventricular substantia nigra and adrenal medulla grafts, with a note on intracranial retinal grafts. | using a rotational behavior animal model, it has been found that embryonic substantia nigra (sn) can be homologously transplanted to the brain lateral ventricles to reverse the effects of sn lesions. these grafts were found to decrease the lesion-induced rotational behavior that was provoked either by apomorphine or amphetamine. this effect was not duplicated by grafts of other embryonic brain regions. the sn grafts produced a dopaminergic reinnervation of the dorsomedial striatum that appeared ... | 1983 | 6652162 |
| an unusual case of miller fisher syndrome. | 1983 | 6654800 | |
| increased agglutinability of bladder epithelial cells by concanavalin a in rats fed several biphenyl derivatives. | biphenyl and its derivatives, 2-aminobiphenyl, 2-nitrobiphenyl, 4-aminobiphenyl, 4-nitrobiphenyl, p-phenylphenol, o-phenylphenol (opp), and o-phenylphenol sodium salt tetrahydrate (opp-na) were examined for their bladder carcinogenicity in rats by a short-term assay for agglutinability of bladder epithelial cells with concanavalin a. increased agglutinability was observed after 1-week treatment with 2.0% and 1.0% opp, 2.0% and 1.0% opp-na, 0.5 and 0.1% 4-aminobiphenyl, and 0.5% 4-nitrobiphenyl i ... | 1983 | 6654951 |
| recurrence risk of neural tube defects following a miscarriage. | data from 280 sibships in three published series were used to see if the increased risk of neural tube defect (ntd) associated with having had a miscarriage in the immediately preceding pregnancy was also found in women with a previous affected pregnancy. a statistically significant relative risk of 4.0 (2-tail p = 0.0111, fisher exact test) was found among such women, and this could not be accounted for by the effect of parity or of a history of miscarriage in general. the finding may be useful ... | 1983 | 6657598 |
| ataxic hemiparesis in patients with primary pontine hemorrhage. | two patients with small primary pontine hemorrhage developed a syndrome identical to ataxic hemiparesis, one of the lacunar syndromes of fisher. the possible mechanisms of the homolateral cerebellar signs, pyramidal signs, and dysarthria are discussed. lesions of the ipsilateral pontine nuclei may be responsible for the homolateral ataxia. | 2016 | 6658962 |
| the effect of aging on vasopressin system in fisher 344 rats. | vasopressin (vp) was measured by ria in the plasma, neurohypophysis (nh) and hypothalamus (ht) of young (2 months), adult (12 months) and old (30 months) male fisher 344 rats, ten of each age. plasma vp concentration was significantly lower in old compared to adult and to young rats. vp content in the nh expressed per mg weight was similar in all three groups, while the hypothalamic vp content was decreased in the aged rats. this suggests that reduced synthesis and release and/or increased degra ... | 1983 | 6667722 |
| effect of feeding fermented milk on the incidence of chemically induced colon tumors in rats. | the effect of feeding skim milk fermented by streptococcus thermophilus or lactobacillus bulgaricus on the incidence of chemically induced colon tumors was studied in rats. weanling fisher-344 rats were fed chow plus skim milk (sm), chow plus sm fermented by s. thermophilus, chow plus sm fermented by l. bulgaricus, or chow plus water until sacrifice at 36 weeks, or before if moribund. colon tumors were induced by s.c. injections of 1,2-dimethylhydrazine hydrochloride during weeks 3 through 22. t ... | 1983 | 6669478 |
| [histological study of urinary bladder tumor: dna of rat urinary bladder tumor caused by n-butyl-n-(4-hydroxybutyl) nitrosamine and that of human bladder tumor]. | male fisher rats were treated with 0.5% bbn, and the appearance of cancer in the rat's bladder was observed successively. the quantities of dna in the normal and tumorous tissues were compared with those in the bladder cancer excised from man; and, the bladder cancer produced in the rat and that occurring in man were compared. 96 rats were divided into 4 groups, and given 8, 16, 24 or 32 weeks of treatment with bbn. papillomas appeared after administration for 8 weeks, and with subsequent increa ... | 1983 | 6677123 |
| work styles of okinawan diving-fishers in relation to decompression sickness and physical complaints. | 1983 | 6679563 | |
| regional vs systemic effect of cis-dichlorodiammine platinum (ii) on squamous cell carcinoma in rats. | utilizing a model that compares the effects of chemotherapeutic agents given regionally vs systemically in the same animal, the effects of cis-dichlorodiammine platinum (ii) (cis-platinum) were evaluated. squamous cell carcinoma was implanted at the bases of both ears of fisher-344 rats. by retrograde cannulation of a branch of the external carotid artery, tumors on the right were treated by intra-arterial infusions of varying doses of cis-platinum while tumors on the left were treated only afte ... | 1983 | 6681693 |
| the adrenocortical stress-response in the aged male rat: impairment of recovery from stress. | to test if the adrenocortical axis of the rat loses sensitivity to negative feedback control during aging, we examined corticosterone secretion under basal, stressed and post-stress conditions in young and in aged fisher male rats. we find no age-related change in the speed or magnitude of the stress response or in the capacity to manifest a corticosterone response following chronic stress. however, we do observe in aging rats an elevation of basal corticosterone and an impaired capacity to adap ... | 1983 | 6683660 |
| hemocytopenia as initial manifestation of systemic lupus erythematosus. prognostic significance. | in 1960 rabinowitz and dameshek emphasized the close relationship between idiopathic thrombocytopenic purpura (itp) and systemic lupus erythematosus (sle) and suggested that itp is often a prodrome of sle. on the basis of tis observation, the present study was designed to investigate the prevalence of sle in patients with the initial diagnosis of itp, autoimmune hemolytic anemia (aiha), fisher-evans' syndrome (f-e) and idiopathic aplastic bone marrow (iabm) and to investigate the salient clinica ... | 1983 | 6687220 |
| isolation of a g0-specific ts mutant from a fischer rat cell line, 3y1. | a ts mutant clone, tsjt60, was isolated from fisher rat cell line, 3y1. during the exponential growth at both 34 and 39.5 degrees c, tsjt60 did not appear as ts mutant cells. however, once entered resting state (g0) under serum deprivation at the confluent state, they could re-enter s phase at 34 degrees c but could not at 39.5 degrees c following the stimulation of cells either by the addition of fetal bovine serum or by trypsinization and replating. these and other results suggested that tsjt6 ... | 1984 | 6692850 |
| effects of hypersensitivity to a halothane metabolite on halothane-induced liver damage. | the effect of immunologic hypersensitivity to a metabolite of halothane (trifluoroacetate) on the halothane-hypoxia-induction model was tested in mice and rats. male fisher 344 rats (200 g) were immunized with ovalbumin-trifluoroacetate (ova-tfa) and the time course of the delayed hypersensitivity response determined. the animals had a peak response between 4 and 6 weeks after immunization. rats were immunized with ova-tfa, ova, or saline 5 weeks before being anesthetized. ten days before anesth ... | 1984 | 6696235 |
| evidence for intrinsic cellular defects of 'complement' receptor-mediated phagocytosis in patients with systemic lupus erythematosus (sle). | fc and 'complement'-mediated phagocytosis of pre-opsonized yeast has been studied in monocytes from 18 patients with sle. monocytes from nine of 18 patients had depressed complement-mediated phagocytosis (p = 0.0001, fishers exact test) but only three of 18 had depressed fc-mediated phagocytosis (ns, fishers exact test). although reduced complement-mediated phagocytosis was correlated with increased frequency of disease manifestations (p less than 0.003, rank correlation) there was no correlatio ... | 1984 | 6697566 |
| first person account: finding myself and loving it. | the article that follows is part of the schizophrenia bulletin's ongoing first person accounts series. we hope that mental health professionals--the bulletin's primary audience--will take this opportunity to learn about the issues and difficulties confronted by consumers of mental health care. in addition, we hope that these accounts will give patients and families a better sense of not being alone in confronting the problems that can be anticipated by persons with serious emotional difficulties ... | 1984 | 6701475 |
| angioimmunoblastic lymphadenopathy with fisher syndrome. | 1984 | 6703951 | |
| neuropathological findings in miller fisher syndrome. | the neuropathological findings in a fatal case of miller fisher syndrome are described. the demyelinating peripheral neuropathy and normal appearance of the central nervous system that were observed support the inclusion of the syndrome within the spectrum of acute inflammatory polyneuropathy. | 1984 | 6736980 |
| effects of chronic manipulations of dietary choline on locomotor activity, discrimination learning and cortical acetylcholine release in aging adult fisher 344 rats. | dietary levels of choline have been shown to influence central cholinergic neurotransmission. to further examine the behavioral and neurochemical effects of dietary choline, adult fisher 344 rats were maintained on choline deficient (n = 6), enriched (n = 6) or usual lab chow (n = 6) diets for 38 weeks. during 14 weeks of free access to these diets, controls gained little weight whereas the deficient group increased and the enriched group decreased. for the remaining 24 weeks the weights of all ... | 1984 | 6738783 |
| the pacing stress test: a reexamination of the relation between coronary artery disease and pacing-induced electrocardiographic changes. | electrocardiographic (ecg) changes during graded pacing-induced tachycardia have been considered unreliable as a test for the presence of coronary artery disease (cad) because of poor sensitivity and specificity. as a result, atrial pacing has not been widely used as an alternative to exercise testing. however, the limited value of the pacing stress test may be related to technical aspects, such as the duration of pacing and ecg monitoring. to study this problem, 22 patients undergoing coronary ... | 1984 | 6741838 |
| a stochastic numerical model of breast cancer growth that simulates clinical data. | a new stochastic numerical model of breast cancer growth is developed. first, the model suggests that gompertzian kinetics does apply but that from time to time, in random fashion, there occurs a spontaneous change in the growth rate or rate of decay of growth, such that the overall growth pattern occurs in a stepwise fashion. according to the model, the average time for the tumor burden to increase from one cell to detection is probably in the range of 8 years. secondly, the model suggests that ... | 1984 | 6744323 |
| oxygen at 2 atmospheres absolute pressure does not increase the radiation sensitivity of normal brain in rats. | cranial radiation was administered to cd fisher rats at 1.0, 1.5 and 2.0 atmospheres absolute oxygen pressure. life span following radiation was recorded. surviving animals were killed at 28 weeks and the brains were examined independently by two neuropathologists. survival time was significantly less in animals receiving higher doses of radiation but showed no relationship to the oxygen pressure in the environment of the animal at the time radiation was administered. microscopic examination of ... | 1984 | 6746347 |
| ronald a. fisher-chance encounters. | 1982 | 6752868 | |
| antitussive effect of guaifenesin in young adults with natural colds. objective and subjective assessment. | the efficacy of guaifenesin in reducing cough frequency in young adults with acute respiratory disease was evaluated by both an objective cough counting system and a questionnaire. a guaifenesin cough preparation and the syrup vehicle were administered in a double-blind manner. coughs were recorded on tape over a 24-hour baseline evaluation period and a 36-hour treatment period for 42 patients. a pronounced diurnal variation in cough frequency was observed. the evaluation of efficacy was based u ... | 1982 | 6754274 |
| regional behavioral variations of epidermoid carcinoma of the head and neck: a study in an animal model. | regional behavioral differences have been observed clinically in epidermoid carcinoma of the head and neck. an animal model was developed for study, using homograft, transplanted epidermoid carcinoma in fisher rats. histopathologic review of tumors of the palate, base of tongue and larynx shows cartilage, arterial wall, surface epithelium and dense connective tissue containing elastic fibers to be relatively resistant to tumor invasion. muscle, bone, vein and loose connective tissues were easily ... | 1982 | 6755115 |
| a comparative trial of intra-nasal beclomethasone dipropionate and sodium cromoglycate in patients with chronic perennial rhinitis. | a double-blind crossover study has compared intra-nasal sodium cromoglycate (scg) with beclomethasone dipropionate (bdp), and both drugs with placebo, in fifty-two chronic perennial rhinitis patients. bdp was significantly more effective in relieving symptoms than scg (76.9% and 50% of the patients improved respectively, p < 0.01). both drugs were more active than placebos but while bdp was very clearly more effective (p < 0.0005) scg was only marginally better than its placebo (p < 0.05, fisher ... | 1980 | 6774833 |
| statistical study of the fisher-race model for human rh genetics. | the technique of chromosomal positioning of inheritable traits (c.p.i.t.) to project relative positions of two or more traits at more than one gene locus was employed to test the validity of the fisher-race model of rh structure. the results of statistical analysis of two large samples of rh phenotype distributions suggest that all models based on vertically related, linked alleles are invalid. on the basis of further analysis, wiener's concept of the structure of the human rh-hr gene locus appe ... | 1980 | 6776028 |
| slime glycolipoproteins and the pathogenicity of various strains of pseudomonas aeruginosa in experimental infection. | several strains of pseudomonas aeruginosa were differentiated on the basis of the surface properties of the cells. fisher immunotype, phage type, polysaccharide depolymerase type, and indirect hemagglutination reactions were used for this purpose. each strain was then studied with respect to events known to occur during the experimental infection of mice with p. aeruginosa. the virulence of the viable cells varied significantly, although all strains were virulent. glycolipoproteins were isolated ... | 1980 | 6777303 |
| [cell-free pseudomonas vaccine. i. enzyme properties and virulence of strains of p. aeruginosa; protective activity of their water-soluble antigens]. | the enzymatic (protease, catalase and gelatinase) activity and virulence of the typing strains obtained from the hungarian national collection of medical bacteria, as well as those of highly toxigenic pa-103 strain and 2 newly isolated p. aeruginosa strains were studied. no correlation between these properties of the strains was observed. aqueous extracts prepared from some of the typing strains contained soluble specific and non-specific protective antigens. the partially purified, low toxic, w ... | 1980 | 6778035 |
| use of pseudomonas aeruginosa lipopolysaccharide immunoadsorbents to prepare high potency, mono-specific antibodies. | potent, mono-specific anti-pseudomonas immunoglobulins were isolated from serum and lung lavage fluid from patients with cystic fibrosis using immunotype specific pseudomonas aeruginosa lipopolysaccharide (lps) substituted immunoadsorbent gel. iodinated monovalent pseudomonas lps somatic antigens, fisher immunotypes, were used as ligands for two different insoluble gel matrices. lps iodination, using the water insoluble chloroglycoluril reagent, permitted quantitation of the percent lps bound as ... | 1980 | 6778926 |
| successful plasmapheresis in the miller-fisher syndrome. | 1981 | 6783167 | |
| successful plasmapheresis in the miller-fisher syndrome. | 1981 | 6786483 | |
| successful plasmapheresis in the miller-fisher syndrome. | 1981 | 6786510 | |
| successful plasmapheresis in the miller-fisher syndrome. | 1981 | 6786587 | |
| diagnosis of bacteremia in children by quantitative direct plating and a radiometric procedure. | during a 1-year period, three bacteriological systems for detecting bacteremia in children were analyzed, namely, the bactec system (johnston laboratories, inc., cockeysville, md.), the fisher/lederle bottle (lederle diagnostics, pearl river, n.y.), and a direct plating method of blood termed quantitative direct plating (qdp). of 2,123 blood cultures, 135 (6.4%) were positive; haemophilus influenzae type b, neisseria meningitidis, and streptococcus pneumoniae accounted for 3.4%, representing 61 ... | 1981 | 6787069 |
| successful plasmapheresis in the miller-fisher syndrome. | 1981 | 6788195 | |
| lipopolysaccharide and high-molecular-weight polysaccharide serotypes of pseudomonas aeruginosa. | the serotype distribution of bacteremic and nonbacteremic clinical isolates of pseudomonas aeruginosa in relation to the fisher immunotyping scheme, the international antigenic typing system (iats), and high-molecular-weight polysaccharide determinants was investigated. of 281 bacteremic isolates, 273 (97.2%) were serotyped by one of the seven iats specificities that correspond to a fisher lipopolysaccharide/high-molecular-weight polysaccharide specificity. in contrast, these seven serotypes acc ... | 1982 | 6798136 |
| effects of insulin on plasma lipoproteins in diabetic ketoacidosis: evidence for a change in high density lipoprotein composition during treatment. | to determine the acute effects of insulin on lipoprotein metabolism, we have followed the plasma lipoprotein lipid and apolipoprotein levels during insulin therapy for the first 24 hr in 13 patients with diabetic ketoacidosis. corrections were made for plasma volume changes during treatment. before insulin treatment, mean plasma triglyceride and cholesterol levels were 574 mg/dl (range 53-2355) and 212 mg/dl (range 118-416), respectively. insulin therapy resulted in rapid decreases in triglyceri ... | 1982 | 6799600 |
| prostate carcinoma tumor size in rats decreases after administration of antagonists of luteinizing hormone-releasing hormone. | the effects of two potent antagonistic analogues of luteinizing hormone-releasing hormone (lh-rh) on the growth of two different models of rat prostate tumors have been investigated. chronic administration of [nac-p-f-dphe1,p-cl-dphe2,dtrp3.6,d-ala10]lh-rh (antagonist i) at 50 micrograms/day for 21 days significantly inhibited the growth of the chemically induced squamous cell carcinoma 11095 in fisher 344 male rats. the weights of the pituitary, ventral prostate, and testes were not significant ... | 1982 | 6803239 |
| field studies: pseudomonas pneumonia of mink. | epizootics of pneumonia in mink caused by pseudomonas aeruginosa were investigated to characterize the serotype of organisms and to identify possible predisposing factors. most epizootics were associated with p aeruginosa fisher serotype 1, and a few were associated with 3 other serotypes. there were no predisposing factors identified that could be used to differentiate farms affected and those not affected with pseudomonas pneumonia. cultural studies indicated that p aeruginosa was present in m ... | 1981 | 6803621 |
| the absence of triphosphate or metaphosphate residues from lipopolysaccharides of the seven fisher immunotypes of pseudomonas aeruginosa. | 1981 | 6803775 | |
| tissue storage of vitamins a and e in rats drinking or infused with total parenteral nutrition solutions. | the total parenteral nutrition (tpn) rat and its sham-operated control were used as a model to compare the metabolism and storage of vitamins a and e when they are administered intravenously or orally. male fisher rats were depleted of both vitamins for several months with a diet free of vitamins a or e, but containing retinoic acid for growth. tpn solutions containing aqueous dispersions of retinol, retinyl palmitate and dl-alpha-tocopheryl acetate were infused at 2.3 ml/h into the jugular vein ... | 1982 | 6805289 |
| sero-genetic studies on the basters of rehoboth, south west africa/namibia. | the basters of rehoboth in south west africa/namibia arose by hybridization between caucasoids and khoi ('hottentots') in the northern cape province of south africa during the eighteenth and nineteenth centuries, followed by migration of a single well-defined party to rehoboth and the consolidation of an ethnocentric nation there. although there has been some gene flow into the population during the twentieth century, the present sero-genetic study contributes further evidence for the hypothesis ... | 2004 | 6805410 |
| synthesis of 8-(methoxycarbonyl)octyl glycosides of o-alpha-l-rhamno-pyranosyl-(1 goes to 3)-o-alpha-l-rhamnopyranosyl-(1 goes to 3)-2-acetamido-2,6-dideoxy-d-glucopyranose; models for the antigen of pseudomonas aeruginosa fisher immunotype 5. | 1982 | 6809330 | |
| sarcocystis and other coccidia in foxes and other wild carnivores from montana. | sarcocystis spp sporocysts were found in feces of 10.1% of 198 red foxes (vulpes vulpes), in 3.2% of 61 bobcats (lynx rufus), in 16.6% of 12 mountain lions (felis concolor), in 16.6% of 6 fisher (martes pennanti), and in none of 20 wolverines (gulo gulo), 4 mink (mustela vison), or 10 raccoons (procyon lotor). sarcocystis muris and toxoplasma gondii were not found in laboratory mice inoculated with feces of bobcats and mountain lions. | 1982 | 6816776 |
| rats highly susceptible to experimental autoimmune encephalomyelitis obtained by crossing rats from strains with low susceptibility. | by crossing and back-crossing three strains of rats, brown-norway, fischer, and pvg, none of which is definitely susceptible to experimental autoimmune encephalomyelitis (eae), it is possible to obtain fully susceptible animals. genetic analysis indicates the presence of ir-genes in at least two of the strains (fisher and pvg) related to the agb complex, and genes of 'resistance' located on another chromosome. the latter appear to be different in the three strains; also the bn strain, which perh ... | 1982 | 6816857 |
| tumor promoter 12-o-tetradecanoylphorbol 13-acetate alters state, fluidity and hydration of 1,2-diacyl-sn-glycero-3-phosphocholine bilayers. | previous results (castagna et al. (1979) febs lett. 100, 62-66; fisher et al. (1979) biochem. biophys. res. commun. 86, 1063-1068) indicated us that the active tumor promoter tpa (12-o-tetradecanoylphorbol 13-acetate) decreased fluorescence polarisation of diphenylhexatriene in lymphoblastoid and rat embryo cells. in the present study, experiments aimed at examining the molecular interactions of tumor promoters with cell membrane components are performed with fully hydrated multibilayers of 1,2- ... | 1983 | 6824654 |
| aging-related decreases in hepatic mitochondrial and cytosolic delta-aminolevulinic acid synthase during experimental porphyria. | the basal- and allylisopropylacetamide-induced activities of the first enzyme of heme biosynthesis, delta-aminolevulinic acid synthase (alas) were measured in hepatic mitochondria and cytosol of young, adult, and aged fisher 344 rats. the total cellular alas activity induced by allylisopropylacetamide decreased 67% with age. the specific activity of mitochondrial alas in normal and induced animals decreased with aging when assayed in whole or broken mitochondria. the levels of alas which accumul ... | 1983 | 6838217 |
| urine profile analysis by field desorption mass spectrometry, a technique for detecting metabolites of xenobiotics. application to 3,5-dinitro-2-hydroxytoluene. | a technique for the detection of biotransformation products of xenobiotics in crude urine extracts by field desorption mass spectrometric profile analysis is described. the method comprises determination of peak profiles of a series of blank and test samples using low resolution field desorption mass spectrometry, comparison of averaged peak profiles and noise reduction by means of fisher and ratio weighting of peak intensities. application of the technique to 3,5-dinitro-2-hydroxytoluene has re ... | 1983 | 6838996 |
| fate of water-insoluble and water-soluble dichlorobenzidine-based pigments in fisher 344 rats. | the fate of two water-insoluble (wi) dichlorobenzidine-based pigments, chlorodiane blue (cdb) and pigment yellow 12 (py12), and of their sulfonated water-soluble (ws) analogs was studied in male fischer 344 rats. water-soluble analogs of chlorodiane blue and pigment yellow 12 were synthesized in order to study the effect of water solubility on the absorption and metabolism of dichlorobenzidine-based pigments. [14c]wi-cbd, [14c]wi-py12, and the water-soluble analogs [14c]ws-cdb and [14c]ws-py12 w ... | 1983 | 6842621 |
| a simple method for determining epithelial cell turnover in small intestine. studies in young and aging rat gut. | epithelial cell migration in animal gut classically is measured by autoradiography after systemic administration of tritiated thymidine. a migration rate is calculated from observations of the leading edge of villus epithelial cells containing labeled nuclei at varying time periods after tritiated thymidine injection. this method is very accurate, but laborious, time consuming, and costly. a new, simplified method for measuring epithelial cell measurement of [3h] deoxyribonucleic acid specific a ... | 1983 | 6847856 |
| chromosome investigations of workers exposed to cadmium in the manufacturing of cadmium stabilizers and pigments. | chromosome analyses were undertaken on 14 workers exposed to cadmium and the results were compared with a corresponding control group. all probands have been employed for many years in cadmium pigment and stabilizer production plants (between 6 and 25 years). the results of the clinical investigations were, for the most part, unspecific, although at the same time some parameters were above the normal (transaminase, beta 2-microglobulin deposit in the urine, as well as cadmium in the blood and ur ... | 1983 | 6851916 |
| the hellinger distance as used for the representation of serological abo distances among earlier human populations. | the hellinger (arccos) distance is examined for the purpose of demonstrating to what extent it represents the differences among populations. when the hellinger distance is employed to estimate gene frequencies, a result very similar to that of the maximum likelihood (bernstein) method can be gained. it is pointed out that in palaeoserological examinations the dobson/ikin method usually mentioned as fisher method is not equivalent to the bernstein method. | 1983 | 6852818 |
| the effects of aging on opioid modulation of feeding in rats. | feeding responses to naloxone and butorphanol tartrate were measured in fisher-344 rats with ages of 2, 12, 22 and 28 months. the two younger groups were 10-100 times more sensitive than the older groups to the suppressive effects of naloxone on feeding. additionally, the older rats were less responsive to the feeding enhancement following butorphanol injections. these results are consistent with reports of age-related changes in endogenous opioid systems. | 1983 | 6855472 |
| species and strain differences in mepirizole-induced duodenal and gastric lesions. | species and strain differences in mepirizole-induced duodenal and gastric lesions were studied. mepirizole at 200 mg/kg given orally induced deep duodenal ulcers and gastric erosions in nonfasted sprague-dawley, fisher, wistar, and donryu rats at an incidence of over 75%. mepirizole at 300 mg/kg given orally also induced penetrating duodenal ulcers in nonfasted rabbits at an incidence of 50%. there was little or no damage to the duodenum and stomach in mice and dogs given 200-300 mg/kg of mepiri ... | 1983 | 6861585 |
| effect of diet on adjuvant-induced disease and mitogenic responses of fisher rats. | fisher rats from a inbred colony, when fed on a salt-free high-protein diet, developed only a mild arthritis after adjuvant injection. their spleen cells failed to respond in vitro to concanavalin a (a t-cell mitogen), although they possessed a b-cell function of plaque formation to sheep red blood cells. when a full salt supplement was included in the diet, or magnesium or copper or zinc was included in the drinking water, adjuvant-induced arthritis was severe and the response to the t-cell mit ... | 1983 | 6862667 |
| supravaginal uterine amputation vs. hysterectomy. effects on coital frequency and dyspareunia. | the author has personally interviewed and examined 105 abdominal hysterectomy patients and 107 supravaginal amputation patients, first preoperatively and then 6 weeks, 6 months and one year postoperatively. at 12 months the follow-up percentage was 99.5 (211/212). this report concentrates on coital frequency and dyspareunia. in the statistical analysis, mcnewar's test of symmetry and the fisher exact test were used. with respect to coital frequency, no statistically significant changes occurred ... | 1983 | 6868962 |
| supravaginal uterine amputation vs. hysterectomy. effects on libido and orgasm. | postoperative symptoms of hysterectomy have received relatively little attention. in the present study, the first author has personally interviewed and examined 105 abdominal hysterectomy patients and 107 patients with supravaginal uterine amputation preoperatively and 6 weeks, 6 months and 12 months postoperatively. participation in the follow-up study was 99.5% (211/212) at one year. this paper deals with the effects of the two operations on libido and the frequency of orgasms. in the statisti ... | 1983 | 6868963 |
| comparisons of liver chromatin proteins and template activities in parental and heterotic rats during postweaned development. | electrophoretic profiles of acid-extractable proteins from holtzman rat liver chromatin display four minor and five major histone bands through certain stages of postweaned development but are qualitatively different from the chromatin protein profiles previously reported during postweaned development for the fisher 344 rat strain and the f344 x holtzman heterotic progeny [tallman, g., et al. (1979). biochem, genet. 17:185]. the protein profiles from the heterotic progeny do not reflect and are ... | 1983 | 6870779 |
| fatty acid composition of tissue phospholipids and prostaglandin excretion in hyperlipidemia induced in rats by implantation of the mammotropic pituitary tumor mtt-f4. | a mammotropic pituitary tumor, mtt-f4, was implanted into male fisher 344 rats for a period of 4 weeks. this tumor induced growth retardation, hyperlipidemia, hepatic hypertrophy and adrenal hyperplasia. lipids were extracted from various tissues. in tumor-bearing rats, phospholipid concentration was found to be increased in plasma, spleen and testis. distribution among the various phospholipid classes was similar to that of controls except in liver and heart, where phosphatidylcholine was incre ... | 1983 | 6877047 |
| statistical mechanical analysis of raman spectroscopic order parameter changes in pressure-induced lipid bilayer phase transitions. | the statistical mechanical cluster theory of fisher as applied by kanehisa and tsong to phospholipid bilayers is modified to describe the effects of hydrostatic pressure on the state of an aqueous dispersion of the phospholipid dipalmitoyl phosphatidylcholine. a high pressure raman scattering cell has been built to obtain the raman spectra of aqueous dispersions of phospholipids as a function of the applied hydrostatic pressure from 0 to 100 atmospheres. predicted thermal and pressure-induced ph ... | 1980 | 6894876 |
| counselling. hidden conflicts: a case study of the fisher family--2. | 1980 | 6898999 | |
| counselling. hidden conflicts: a case study of the fisher family - 3. | 1980 | 6899003 | |
| pelvic actinomycosis following insertion of an intrauterine contraceptive device. | a case of actinomycosis following insertion of an intrauterine contraceptive device is reported. the patient was treated successfully by antibiotic therapy and conservative surgery. | 1980 | 6930254 |
| studies on blood groups and other genetic markers in forest nentzi: variation among the subpopulations. | a samoyed-speaking group of fishers, hunters, and deer breeders numbering 1500 in total has been investigated. seven territorial subgroups were examined with respect to 15 genetic systems. the presence of a2, cde, cwde, kpa, ak2, pc, gmfb, and gmfnb genes or haplotypes in low or moderate frequencies was observed. an unexpected finding was a deleted gm(-;n;gb) phenotype in three siblings. significant local genetic heterogeneity was observed with regard to ab0, rh, tf, pgm1, 6-pgd, and gm systems. ... | 1980 | 6937432 |
| genetics of natural resistance to thermal injury. | the possible influence of genetic factors in conditioning the host's natural resistance to the lethal effects of severe thermal injury has been studied in 908 rats of comparable age and weight, originating from two outbred, eight inbred, and two congenic strains of animals of defined genetic background. each animal was exposed to a standard, full-thickness, 40% body surface area skin burn by controlled contact with a heated metal plate. the 21-day postburn mortality was 100% in 217 fisher (f-344 ... | 1982 | 6977344 |
| report of the federal panel on formaldehyde. | the federal panel on formaldehyde concluded that definitive experiments exist which demonstrate the mutagenicity and carcinogenicity of formaldehyde under laboratory conditions. formaldehyde induces both gene mutations and chromosomal aberrations in a variety of test systems. inhalation of formaldehyde causes cancer of the nose in rats. the concentrations of formaldehyde in inhaled air that caused nasal cancer in fisher 344 rats are within the same order of magnitude as those to which humans may ... | 1982 | 6977445 |
| aphasic adults and their decisions on driving: an evaluation. | this study evaluated the propriety of decisions by aphasic adults to avoid or to return to driving following a cerebrovascular accident. a comparison was made of a rehabilitation team's assessments of driving skills with a group of 10 aphasic adults who had chosen to return to driving without professional consultation and 10 aphasic adults who had not returned to driving. the fisher exact probability test found that the team-assigned driver and nondriver groupings agreed with the patients' own g ... | 1980 | 6986136 |
| fisher syndrome: a recent follow-up. | 1980 | 6986569 | |
| [cystoscopy (1879-1979) (centennial of a transcendental invention)]. | the authors make a historical review of the successive stages in man's attempt to be able to observe directly the inside of the cavities of the human body and more precisely of the bladder, which from the start long ago, led to the apparatuses invented during the first half of the 19th century (bozzini, ségalas, bonbalgini, fisher, avery, desormeaux, hacken, cruise, grünfeld, luys, etc.) until the 9th march 1879 when maximilian nitze presented in the vienna medical society and published in the j ... | 1980 | 6987957 |
| studies of the immediately vascularized skin allograft. | in order to evaluate the effect of the nature of revascularization on survival rates of skin allografts, a rat model was devised which provided simultaneous and immediate establishment of arterial and venous blood supply to a composite skin-renal allograft. for 5 days after transplantation the skin portion of the composite grafts appeared normal, with minimal inflammation in 11 recipients. from 6 to 11 days, in 6 rats, active rejection developed with a marked inflammatory reaction of the skin-ki ... | 1980 | 6992906 |
| the medical examiner and medical education (russell s. fisher). | 1980 | 6995265 | |
| correlation studies of entero-set 20, api 20e and conventional media systems for enterobacteriaceae identification. | the entero-set kit (fisher diagnostics) is a 20-biochemical-test system used in the identification of members of the enterobacteriaceae. this kit was compared with the api 20e (analytab products) and conventional media systems, using 505 (303 stock and 202 clinical) strains of enterobacteriaceae. when the entero-set and api 20e results were compared with those of the conventional media system, the entero-set performed as well as the api 20e in overall identification. comparison of common biochem ... | 1981 | 7007414 |
| salute to c. miller fisher. | 1981 | 7008751 | |
| improved survival for patients with advanced carcinoma of the head and neck treated with methotrexate-leucovorin prior to definitive radiotherapy or surgery. | patients presenting with stage iii-iv squamous carcinoma of the head and neck often relapse following aggressive surgery and/or radiotherapy. in an attempt to increase survival in this high risk group of patients, hd-mtx, 3 gm./m2/dose, given weekly, was administered to 21 inoperable patients with stage iii/iv squamous carcinoma of head and neck prior to, and for 1 month after, definitive surgery and/or radiotherapy. six of 11 patients (55%) who showed a significant response (greater than 50% re ... | 1981 | 7017315 |
| sterol metabolism in the rat: effect of alcohol on sterol metabolism in two strains of rats. | sterol metabolism studies using a combination of isotopic and chromatographic procedures were carried out in two strains of rats fed 5% ethanol (36% of calories) in the diet. feeding ethanol to the fisher rat over 17 days produced no significant changes in body weight. cholesterol levels in various tissues were elevated in the ethanol-fed group: plasma cholesterol, +61%; liver cholesterol, +47%; and bile cholesterol, +57%. the alcohol-fed fisher rat showed several changes in sterol metabolism ov ... | 1981 | 7018302 |
| development of a folacin bioassay in rats. | the objective of this study was to determine if the relationship between dietary folic acid and liver folacin concentration could serve as a quantitative standard response curve for a folacin bioassay. this paper examines the time required for liver folacin depletion, the effect of the supplementation period on the range of the linear response and the precision of the standard curve. male weanling fisher strain rats were offered a low folacin diet for 31 days. at the end of the depletion period ... | 1982 | 7054472 |
| dna polymerase-alpha. common polypeptide core structure of three enzyme forms from human kb cells. | aqueous extracts of exponentially growing human kb cells contain three quantitatively significant forms of dna polymerase-alpha activity. the predominant form (about 70% of total cellular activity), which is recovered from the cytoplasm, has been previously purified to near-homogeneity and structurally characterized (fisher, p. a., and korn, d. (1977) j. biol. chem. 252, 6528-6535). the other two polymerase forms include a minor cytoplasmic activity (about 20% of total cellular activity), dna po ... | 1982 | 7056756 |
| age-related failure of volume-pressure-mediated vasopressin release. | osmoreceptor sensitivity, as estimated by the plasma vasopressin (avp) response to hypertonic saline infusion, increases with age. we studied volume-pressure sensitivity, as estimated by the plasma avp response to orthostasis, in healthy young (19-31 yr old; n = 12) and old (62-80 yr old; n = 15) subjects. after remaining recumbent overnight (minimum of 8 h), subjects stood quietly for 8 min. cardiovascular changes on standing were not influenced by age. the peak plasma avp response was greater ... | 1982 | 7056850 |
| binding of chloroform to mouse and rat hemoglobin. | the covalent binding of chemical carcinogens and mutagens to hemoglobin has been proposed as a dose monitor for environmental exposure. the binding of chloroform to hemoglobin in rats was demonstrated to result from the formation of addition adducts to amino acids in the globin. the altered amino acids were isolated with an amino acid analyzer employing ion exchange chromatography. the covalent binding of orally-administered [14c]chloroform to rat hemoglobin reached a peak within 10 h. afterward ... | 1982 | 7060223 |
| strain difference in thermoregulation of rats surviving extreme heat. | the survival times of unanesthetized rats in 42.5 degree c. 48% rh were studied in 12 different strains. in males, sprague-dawley rats (p less than 0.01) and fisher 344/mk (p less than 0.05) showed significantly higher heat tolerance than the other 9 strains. among sprague-dawley rats, females tolerated heat longer than males (p less than 0.05). there was no difference in lethal body temperature according to strains and exposure temperatures (38.5-48.5 degree c). maximum survivable body temperat ... | 1982 | 7061293 |
| immunosuppressive activity of succinylacetone. | sa, an inhibitor of ala dehydrase, the second enzyme of the heme biosynthetic pathway, has been shown to exert immunosuppressive activity in several systems. when the walker 256 tumor was grown subcutaneously in outbred sprague-dawley rats, sa prevented rejection of the tumor by the host. human peripheral blood lymphocyte transformation in response to mitogens and antigens in vitro was markedly impaired by addition of sa to the medium. addition of hematin to the medium did not reverse the sa-med ... | 1982 | 7061925 |
| complement receptors of rat macrophages. | some species, including rabbits, guinea pigs, and humans, have complement receptors on resident alveolar macrophages, whereas swiss mice lack detectable receptors on these macrophages. using complement-coated sheep erythrocytes or bacteria, we were unable to detect complement receptors (cr1, cr2, or cr3) on resident alveolar macrophages of male sprague-dawley rats. nonelicited peritoneal macrophages from sprague-dawley rats had cr1 and cr3 receptors and were able to bind bacteria opsonized with ... | 1982 | 7062316 |
| a program to compute power of fisher test at interim point in a clinical trial. | 1982 | 7067420 | |
| schistosoma intercalatum (fisher, 1934) infection in sheep. | parasitological and clinico-pathological aspects of schistosoma intercalatum infection in sheep were studied after exposure to 5000 cercariae per animal. it was shown that the infection, in spite of relatively high tissue egg counts, only gave rise to low-grade clinico-pathological manifestations with almost unaffected blood parameters. the parasites were mainly located in the lower part of the intestinal tract, and the number of eggs being passed in faeces was very low. | 1982 | 7069181 |
| pharmacokinetics of acrylamide in fisher-344 rats. | 1982 | 7071872 | |
| the effect of vitamin e deficiency on some platelet membrane properties. | the effects of alpha-tocopherol (vitamin e) deficiency on membrane properties of platelets were studied to determine if vitamin e has a measureable stabilizing role in biological membranes. three groups of rats and three of mice were studied: two groups consisted of fisher strain rats and one of sprague-dawley rats fed a draper corn oil diet with and without high levels of supplementary vitamin e. the mice were two groups of balb/c animals maintained on an 8% hydrogenated coconut oil diet, and o ... | 1982 | 7077141 |
| pelvic infection after elective abortion associated with chlamydia trachomatis. | two groups in denmark and sweden, totalling 943 healthy women in the first trimester of pregnancy who were undergoing elective abortion, were examined in a prospective study. group 1 consisted of 432 women from denmark, all examined prior to and 2 weeks after the operation. at the first examination, samples were taken from the cervix for the isolation of chlamydiae and gonococci. chlamydia trachomatis was isolated from 23 (5.3%) of the women. postoperatively, 15 patients developed acute pelvic i ... | 1982 | 7078867 |
| detection of carcinogenic exposures by urinalysis: induction of cell-mediated immunity. | studies were undertaken to determine whether urine collected from rats during the 24 h following exposure to the colon carcinogen 1,2-dimethylhydrazine (dmh) contained substances which would induce specific antitumor immunity. the evaluation for such components was carried out by administering the test and control urine to young male adult fisher f344 inbred rats and then establishing the animals' antitumor cell-mediated immunity (cmi) at a 14-day post-exposure interval. the cmi was measured by ... | 1982 | 7101323 |
| brainstem encephalitis and the syndrome of miller fisher: a clinical study. | 1982 | 7104664 |