Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| [efficacy of individualized sublingual immunotherapy with dermatophagoides farinae drops on patients with allergic rhinitis of different age groups]. | to evaluate the efficacy of personal sublingual immunotherapy (slit) with dermatophagoides to study the efficacy of dermatophagoides farinae drops for allergic rhinitis (ar) of different age groups. | 2014 | 25185278 |
| [skin prick test using two different allergen prick reagents, a comparative study in shanghai]. | to compare the results of skin prick test with allergens of allergopharma company or alk company in shanghai area. | 2014 | 25185289 |
| progress in the development of specific immunotherapies for house dust mite allergies. | allergen-specific immunotherapy is used to treat patients exposed and co-sensitized to the two common house dust mites, dermatophagoides pteronyssinus and dermatophagoides farinae. based on seroepidemiological studies and a detailed characterization of mite allergens, an optimal immunotherapeutic product should associate extracts from the two dermatophagoides species, and include both bodies and fecal particles. both subcutaneous and sublingual immunotherapies performed with aqueous mite extract ... | 2014 | 25187166 |
| design of a proder f 1 vaccine delivered by the mhc class ii pathway of antigen presentation and analysis of the effectiveness for specific immunotherapy. | dermatophagoides farinae (der f 1) is one of leading cause for allergic asthma, and allergen-specific immunotherapy (sit) is currently recognized as the only etiological therapy to ameliorate asthmatic symptom. the current study was designed on the major histocompatibility complex (mhc) class ii pathway, invariant chain (ii)-segment hybrids as vaccine basis to explore the efficacy of der f 1 hybrid vaccine by virtue of ii as carrier in enhancing the protective immune response to asthma. initiall ... | 2014 | 25197336 |
| house dust mite allergen levels in households and correlation with allergic rhinitis symptoms. | house dust mite (hdm) allergen is a risk factor for the development of allergic rhinitis (ar). | 2014 | 25198017 |
| a multicenter study of the clinical features of allergic rhinitis in central china. | several epidemiological surveys of allergic rhinitis (ar) have been conducted in china. however, the clinical features of ar are still not clear enough. the aim of the current study was to perform a multicenter investigation to evaluate the clinical features of ar in china. | 2014 | 25198025 |
| association of cytokines in individuals sensitive and insensitive to dust mites in a brazilian population. | allergic reaction to dust mites is a relatively common condition among children, triggering cutaneous and respiratory responses that have a great impact on the health of this population. anaphylactic hypersensitivity is characterized by an exacerbated response involving the production of regulatory cytokines responsible for stimulating the production of ige antibodies. | 2014 | 25238536 |
| regulation of constitutive neutrophil apoptosis due to house dust mite allergen in normal and allergic rhinitis subjects. | house dust mite (hdm) is a primary allergen in allergic rhinitis (ar) and asthma. neutrophil apoptosis is associated with allergic diseases and innate immunity to infection. the present study examined how hdm affects constitutive neutrophil apoptosis in normal and ar subjects. total ige increased in ar subjects when compared to normal subjects, and patients with ar were hdm-specific ige positive (+), which is specific ige to dermatophagoides pteronissinus and dermatophagoides farinae. in normal ... | 2014 | 25243400 |
| allergy to dust mites may contribute to early onset and severity of alopecia areata. | a higher risk of allergic diseases such as rhinitis, asthma and atopic eczema (atopic dermatitis) has been reported for patients with alopecia areata (aa) compared with the general population, but the significance of this is still largely unclear. | 2015 | 25252126 |
| the efficacy of sublingual immunotherapy with dermatophagoides farinae vaccine in a murine atopic dermatitis model. | sublingual immunotherapy (slit) is a potential treatment for house dust mite-induced atopic dermatitis (ad). however, the mechanisms of action are not clear. | 2015 | 25258013 |
| sensitivity to five types of house dust mite in a group of allergic egyptian children. | background: the published data on house dust mite (hdm) sensitization from egypt are scanty. we sought to investigate the sensitization to five different types of hdm among a group of allergic children in a trial to outline the most frequent sensitizing strains in the cairo province. methods: we consecutively enrolled 100 asthmatic patients, aged 1-7 years, of whom 22 had concomitant skin allergy. skin prick testing was performed using allergen extracts of dermatophagoides pteronyssinus, dermato ... | 2014 | 25276487 |
| damp molecules s100a9 and s100a8 activated by il-17a and house-dust mites are increased in atopic dermatitis. | s100a9 and s100a8 are called damage-associated molecular pattern (damp) molecules because of their pro-inflammatory properties. few studies have evaluated s100a9 and s100a8 function as damp molecules in atopic dermatitis (ad). we investigated how house-dust mites affect s100a9 and s100a8 expression in th2 cytokine- and th17 cytokine-treated keratinocytes, and how secretion of these molecules affects keratinocyte-derived cytokines. finally, we evaluated expression of these damp molecules in ad pa ... | 2014 | 25308296 |
| luffa cylindrica suppresses development of dermatophagoides farinae-induced atopic dermatitis-like skin lesions in nc/nga mice. | the fruit pulp of luffa cylindrica roemer (cucurbitaceae) (lc) has been used to induce hemostasis, resolve phlegm and clear fever in traditional korean medicine. however, the efficacy of lc has not been examined in atopic dermatitis (ad). | 2015 | 25327534 |
| a dna vaccine encoding a chimeric allergen derived from major group 1 allergens of dust mite can be used for specific immunotherapy. | immunization with dna-based constructs has been shown to be against the antigen and the response is skewed in such a way as to ameliorate the symptoms of allergic disease. this approach is particularly useful in the treatment of allergic inflammatory diseases, such as asthma. the major group 1 allergen from house dust mites is one of the triggers of allergic asthma. this study explores whether a chimeric gene r8, derived from the major group 1 allergen of house dust mite species (dermatophagoide ... | 2014 | 25337189 |
| the serine protease inhibitor, 4-(2-aminoethyl) benzene sulfonyl fluoride hydrochloride, reduces allergic inflammation in a house dust mite allergic rhinitis mouse model. | serine protease inhibitors are involved in immune development, anti-inflammatory mechanisms, and tissue repair. in the present study, the serine protease inhibitor 4-(2-aminoethyl) benzene sulfonyl fluoride hydrochloride (aebsf) was evaluated for its prophylactic and therapeutic applications in a mouse model of allergic rhinitis (ar). | 2014 | 25374756 |
| influence of asian dust particles on immune adjuvant effects and airway inflammation in asthma model mice. | an asian dust storm (ads) contains airborne particles that affect conditions such as asthma, but the mechanism of exacerbation is unclear. the objective of this study was to compare immune adjuvant effects and airway inflammation induced by airborne particles collected on ads days and the original ads soil (cj-1 soil) in asthma model mice. | 2014 | 25386753 |
| distribution of inhalant allergies in pediatric patients presenting with allergic complaints in the eastern anatolia region. | the objective of this study was to define the distribution of inhalant allergens in pediatric patients in whom sensitization was diagnosed with a skin prick test (spt) who had presented with allergic complaints. in addition, the correlation between the inhalant allergens detected on the spt and the patients' demographic features, diagnosis, and laboratory findings was defined. | 0 | 25411950 |
| the leaves of broussonetia kazinoki siebold inhibit atopic dermatitis-like response on mite allergen-treated nc/nga mice. | broussonetia kazinoki siebold. (b. kazinoki) has long been used in the manufacture of paper in asian countries. although b. kazinoki leaves (bk) have been employed in dermatological therapy, use of bk has not been tested in patients with atopic dermatitis (ad). using nc/nga mice, which are genetically predisposed to develop ad-like skin lesions, we confirmed the efficacy of bk in ad treatment. bk extract was applied topically to dermatophagoides farinae-induced ad-like lesions in nc/nga mice, an ... | 2014 | 25414775 |
| food allergy enhances allergic asthma in mice. | atopic march refers to the typical transition from a food allergy in early childhood to allergic asthma in older children and adults. however the precise interplay of events involving gut, skin and pulmonary inflammation in this process is not completely understood. | 2014 | 25433406 |
| [choosing the best panel of aeroallergen prick-tests for patients in lebanon with rhinitis and asthma: a retrospective study of 2350 patients]. | the aim of this study was to evaluate the profile of skin prick-test reactivity to different aeroallergens in patients with rhinitis and asthma in lebanon and its geographic variation within the country. it was also to suggest a minimal panel of allergens that should be used to detect sensitized patients. | 2014 | 25433589 |
| the draft genome, transcriptome, and microbiome of dermatophagoides farinae reveal a broad spectrum of dust mite allergens. | a sequenced house dust mite (hdm) genome would advance our understanding of hdm allergens, a common cause of human allergies. | 2015 | 25445830 |
| expression and refolding of mite allergen pro-der f1 from inclusion bodies in escherichia coli. | house dust mite (dermatophagoides farinae) allergen der f1 is one of the most important indoor allergens associated with asthma, eczema and allergic rhinitis in humans. therefore, sufficient quantities of der f1 cysteine protease to be used for both experimental and therapeutic purposes are very much needed. using recombinant dna technology, high expression rates of cysteine proteases were obtained. the cdna sequence encoding pro-der f1 was cloned and expressed in escherichia coli using the t7 b ... | 2015 | 25462803 |
| prevalence of and risk factors for increased serum levels of allergen-specific ige in a population of norwegian dogs. | the importance of different allergens in association with ige production and canine atopic dermatitis (cad) has been poorly studied and few studies exist on factors influencing allergen-specific ige antibodies in serum. the aim of this cross-sectional study was to investigate the prevalence of elevated ige levels to different environmental allergens in norwegian dogs with a suspicion of cad. the secondary aim was to identify risk factors associated with elevated serum levels of allergen-specific ... | 2014 | 25475748 |
| [sensitisation profile to airborne allergens of patients followed for asthma in cotonou, benin. a cross-sectional study using prick-tests]. | the sensitisation profile to airborne allergens of asthma patients followed in benin is not known. | 2015 | 25480388 |
| group 1 allergen genes in two species of house dust mites, dermatophagoides farinae and d. pteronyssinus (acari: pyroglyphidae): direct sequencing, characterization and polymorphism. | group 1 allergens of dermatophagoides farinae (der f 1) and d. pteronyssinus (der p 1) dominate overall allergic responses in house dust mite allergy patients. the need for accurate identification and characterization of representative variants of group 1 allergens in any given geographic locality has been emphasized for development of appropriate allergen extracts. regional amino acid sequence polymorphism has been described but the extent of this polymorphism is not well understood. such data ... | 2014 | 25494056 |
| perennial aeroallergens sensitisation and risk of asthma in african children and adolescents: a case-control study. | the distribution and impact of various aeroallergens on asthma occurrence vary across regions. we investigated the association between sensitisation to perennial aeroallergens and asthma risk in children and adolescents in yaounde, cameroon. | 2015 | 25494554 |
| increased il-22 level in allergic rhinitis significantly correlates with clinical severity. | il-22 regulates various processes and has been linked to diverse effects. however, the importance of il-22 in the pathogenesis of allergic rhinitis (ar) remains poorly understood. this study sought to evaluate the levels of il-22 and il-17a in ar patients and their association with clinical severity ofn ar. | 2014 | 25514475 |
| [experimental study on the der f 1 mrna molecules derived from dermatophagoides farinae for specific immunotherapy on murine model of asthma]. | to investigate the effect of der f 1 mrna molecules for specific immunotherapy on murine model of asthma. | 2014 | 25518589 |
| [effect of immunotherapy with recombinant allergen group 3 from dermatophagoides farinae in asthma mice]. | to explore the effect of specific immunotherapy with major 3 group recombinant allergen rder f 3 of dermatophagoides farinae in murine asthma model. | 2014 | 25518591 |
| human umbilical cord blood mesenchymal stem cell-derived pge2 and tgf-β1 alleviate atopic dermatitis by reducing mast cell degranulation. | mesenchymal stem cell (msc) is a promising tool for the therapy of immune disorders. however, their efficacy and mechanisms in treating allergic skin disorders are less verified. we sought to investigate the therapeutic efficacy of human umbilical cord blood-derived mscs (hucb-mscs) against murine atopic dermatitis (ad) and to explore distinct mechanisms that regulate their efficacy. ad was induced in mice by the topical application of dermatophagoides farinae. naïve or activated-hucb-mscs were ... | 2015 | 25522163 |
| [effects of sublingual immunotherapy on serum il-17 and il-35 levels in children with allergic rhinitis or asthma]. | to study the clinical effect and mechanisms of specific sublingual immunotherapy (slit) for the treatment of allergic rhinitis or asthma in children. | 2014 | 25523566 |
| in silico structural analysis of group 3, 6 and 9 allergens from dermatophagoides farinae. | dermatophagoides farinae (hughes; acari: pyroglyphidae) are the predominant source of dust mite allergens, which provoke allergic diseases, such as rhinitis, asthma and eczema. of the 30 allergen groups produced by d. farinae, the der f 3, der f 6 and der f 9 allergens are all trypsin‑associated proteins, however little else is currently known about them. the present study used in silico tools to compare the amino acid sequences, and predict the secondary and tertiary structures of der f 3, der ... | 2015 | 25572027 |
| [sensitization to blomia tropicalis among asthmatic patients in yaoundé, cameroon]. | the aim of this study was to determine the prevalence and investigate associated factors for blomia tropicalis (bt) sensitization in adolescent and adult patients with asthma in yaoundé (cameroon). | 2015 | 25618201 |
| cloning, expression, and analysis of a cdna coding for the dermatophagoides farinae group 21 (der f 21) allergen. | domestic mite species like dermatophagoides farinae induce allergies in people worldwide. here, the cdna coding for group 21 allergen of dermatophagoides farinae (hughes; acari: pyroglyphidae) from china was cloned, sequenced, and expressed in e. coli to aid in the development of diagnostic and treatment options for domestic mite hypersensitivity. first, the der f 21 cdna fragment was synthesized by rt-pcr; the confirmed full-length sequence comprised 411 nucleotides. the cdna was ligated to the ... | 2014 | 25628789 |
| reproductive biology of euroglyphus maynei with comparisons to dermatophagoides farinae and d. pteronyssinus. | the reproductive biology of the house dust mite, euroglyphus maynei, is not well studied. this mite is usually less common in homes than dermatophagoides farinae and d. pteronyssinus. when it is present, it usually co-inhabits with the dermatophagoides spp. and is more restricted in geographical distribution. in this study, the duration of the life cycle (egg to adult) at 23 and 30 °c at 75% relative humidity (rh) and fecundity at 23 °c and 75% rh were determined for e. maynei and the data were ... | 2015 | 25633266 |
| asian sand dust aggregate causes atopic dermatitis-like symptoms in nc/nga mice. | asian sand dust (asd) originates from the arid and semiarid areas of china, and epidemiologic studies have shown that asd exposure is associated with various allergic and respiratory symptoms. however, few studies have been performed to assess the relationship between skin inflammation and asd exposure. | 2015 | 25642251 |
| studies of house dust mites can now fully embrace the "-omics" era. | 2015 | 25662308 | |
| belching, regurgitation, chest tightness and dyspnea: not gastroesophageal reflux disease but asthma. | belching is a common symptom of gastroesophageal reflux disease. if the symptoms are not relieved after anti-reflux treatment, another etiology should be considered. here, we report a case of a 43-year-old man who presented with belching, regurgitation, chest tightness and dyspnea for 18 mo, which became gradually more severe. gastroscopic examination suggested superficial gastritis. twenty-four-hour esophageal ph monitoring showed that the demeester score was 11.4, in the normal range. high-res ... | 2015 | 25663791 |
| three-year follow-up results of sublingual immunotherapy in patients with allergic rhinitis sensitized to house dust mites. | this study investigated the long-term efficacy, safety, and compliance associated with sublingual immunotherapy (slit) in korean patients with allergic rhinitis sensitized to house dust mites. | 2015 | 25729618 |
| in vitro evaluation of allergen potencies of commercial house dust mite sublingual immunotherapy reagents. | the clinical efficacy of allergen-immunotherapy is known to be dose dependent. however, optimal maintenance dosage has not yet been determined for sublingual immunotherapy (slit). furthermore, since companies adopt their own units for expression of allergenicity, the allergen concentrations of individual reagents cannot be compared easily. we sought to measure and compare the allergenicities of 3 commercially available house dust mite (hdm) slit regents and a subcutaneous immunotherapy reagent. | 2015 | 25729619 |
| skin prick test in patients with chronic allergic skin disorders. | chronic allergic skin disorders are the inflammatory and proliferative conditions in which both genetic and environmental factors play important roles. chronic idiopathic urticaria (ciu) and atopic dermatitis (ad) are among the most common chronic allergic skin disorders. these can be provoked by various food and aeroallergens. skin prick tests (spts) represent the cheapest and most effective method to diagnose type i hypersensitivity. positive skin tests with a history suggestive of clinical se ... | 2017 | 25814704 |
| early-life house dust mite allergens, childhood mite sensitization, and respiratory outcomes. | exposure to indoor allergens during early life may play a role in the development of the immune system and inception of asthma. | 2015 | 25858551 |
| induction of muc5ac mucin expression by histamine through the activation of its core promoter region. | this study provides evidence that histamine induced muc5ac mrna expression through the activation of the core region of its promoter. it may also help in approaching new therapeutic strategies in airway mucins hypersecretory diseases. | 2015 | 25872410 |
| phase ii/iii clinical trial to assess the tolerability and immunological effect of a new updosing phase of dermatophagoides mix-based immunotherapy. | immunologically enhanced subcutaneous specific immunotherapy (scit) has been developed with a fast and simplified updosing phase containing equal parts of the house dust mites (hdm) dermatophagoides pteronyssinus and dermatophagoides farinae (dermatophagoides mix) adsorbed on aluminum hydroxide. | 2015 | 25898693 |
| [[expression of house dust mite allergens der f1 and der f2 in nicotiana benthamiana leaves]. | the class e immunoglobulins (ige) is known to recognize conformational epitopes and therefore the native conformation of recombinant allergens is essential for their using in test-systems. recombinant dermatophagoides farinae house dust mite (hdm) allergens der f1 and der f2 were expressed in bacteria escherichia coli and nicotiana benthamiana plants. it has been shown that ige in sera from children allergic to hdm recognizes der f2 expressed both in e. coli and n. benthamiana. mature form of de ... | 2015 | 25898757 |
| asthma, airway symptoms and rhinitis in office workers in malaysia: associations with house dust mite (hdm) allergy, cat allergy and levels of house dust mite allergens in office dust. | a prevalence study was conducted among office workers in malaysia (n= 695). the aim of this study was to examine associations between asthma, airway symptoms, rhinitis and house dust mites (hdm) and cat allergy and hdm levels in office dust. medical data was collected by a questionnaire. skin prick tests were performed for hdm allergens (dermatophagoides pteronyssinus, dermatophagoides farinae) and cat allergen felis domesticus. indoor temperature and relative air humidity (rh) were measured in ... | 2015 | 25923543 |
| population growth and allergen content of cultured euroglyphus maynei house dust mites. | the house dust mite, euroglyphus maynei, occurs in homes worldwide and is an important source of many allergens. many patients sensitive to dermatophagoides farinae and d. pteronyssinus are also sensitive to e. maynei. extracts to detect sensitivity to e. maynei and reagents to detect e. maynei allergens in the environment or in cultures are not readily available. information for the culture of e. maynei and for the determination of allergen and endotoxin levels in cultures is limited. | 2015 | 25924978 |
| efficacies of immunotherapy with polypeptide vaccine from proder f 1 in asthmatic mice. | allergic asthma is associated with the major house dust mite group 1 allergens der p 1 and der f 1, which belongs to the papin-like protease family and is the most potent of indoor allergens and allergen-specific immunotherapy (sit), is seen as effective intervention for the entity. the current study was designed to verify the sit efficacies of the enzymatic hydrolysates (papain and trypsin) in mice with asthma. we initially developed the asthmatic mouse models with proder f 1, and respectively ... | 2015 | 25932130 |
| [profile of sensitization to allergens in children with atopic dermatitis assisting to allergology service of university hospital, nuevo leon, mexico]. | sensitization to allergens in atopic dermatitis patients is a risk factor for developing asthma and allergic rhinitis in the future,as well as an aggravating factor in the course of the disease. recent studies have attributed the activity of the proteases of some antigens to cause a grater defect in the epithelial barrier and a more severe disease. | 0 | 25958372 |
| house dust mite allergen regulates constitutive apoptosis of normal and asthmatic neutrophils via toll-like receptor 4. | house dust mites (hdms) induce allergic diseases such as asthma. neutrophil apoptosis is an important process of innate immunity, and its dysregulation is associated with asthma. in this study, we examined the effects of hdm on constitutive apoptosis of normal and asthmatic neutrophils. extract of dermatophagoides pteronissinus (dp) inhibited neutrophil apoptosis, but dermatophagoides farinae extract had no effect. anti-apoptotic signaling mediated by dp involves in tlr4, lyn, pi3k, akt, erk, an ... | 2015 | 25973752 |
| sensitization profile to allergens in patients using multi-test ii. | introduction medical intervention in allergies has broadened its perspective, also focusing in the quality of life of patients. patients are instructed, before using pharmacotherapy agents, to avoid the causal agent. objective this study aims to analyze the sensitization profile of patients with allergic complaints and identify possible characteristics specific to each age group and gender. methods a descriptive cross-sectional study included data collected from medical records (from multi-test ... | 2014 | 25992129 |
| efficacy of sublingual immunotherapy with dermatophagoides farinae extract in monosensitized and polysensitized patients with allergic rhinitis: clinical observation and analysis. | to investigate differences in the efficacy of sublingual immunotherapy with dermatophagoides farinae drops in monosensitized and polysensitized allergic rhinitis patients. | 2015 | 26000283 |
| [efficacy of sublingual immunotherapy with dermatophagoides farinae drops on patients with allergic rhinitis of different symptom severity]. | to evaluate the efficacy of sublingual immunotherapy (slit) with dermatophagoides farinae drops for allergic rhinitis (ar) of different symptom severity. | 2015 | 26012292 |
| preparation of a polyclonal antibody that recognizes a unique galactoseβ1-4fucose disaccharide epitope. | galactoseβ1-4fucose (galβ1-4fuc) is a unique disaccharide unit that has been found only in the n-glycans of protostomia. we demonstrated that this unit has a role as an endogenous ligand for caenorhabditis elegans galectins. this unit is also recognized by fungal and mammalian galectins possibly as a non-self glycomarker. in order to clarify its biological function, we made a polyclonal antibody using (galβ1-4fuc)n-bsa as the antigen, which was prepared by crosslinking galβ1-4fuc-o-(ch2)2-sh and ... | 2015 | 26025207 |
| structural analysis of der p 1-antibody complexes and comparison with complexes of proteins or peptides with monoclonal antibodies. | der p 1 is a major allergen from the house dust mite, dermatophagoides pteronyssinus, that belongs to the papain-like cysteine protease family. to investigate the antigenic determinants of der p 1, we determined two crystal structures of der p 1 in complex with the fab fragments of mabs 5h8 or 10b9. epitopes for these two der p 1-specific abs are located in different, nonoverlapping parts of the der p 1 molecule. nevertheless, surface area and identity of the amino acid residues involved in hydr ... | 2015 | 26026055 |
| microfluidic system for high-throughput immunoglobulin-e analysis from clinical serum samples. | rapid and high-throughput analytical techniques for ige that requires a small serum amount are very important, especially for pediatric patients. in these patients, blood is collected from veins, which is painful compared to fingertip blood collection. herein, a novel microfluidic system capable of high-throughput parallel analyses of allergen-specific ige from small amounts of patient serum was successfully developed. a six-plex immunoassay was constructed within a microfluidic chip, and the en ... | 2015 | 26078132 |
| the dermatophagoides farinae group 22 allergen: cloning and expression in escherichia coli. | dermatophagoides farinae (hughes) (acari: pyroglyphidae) and other domestic mites produce allergens that affect people worldwide. here, the complementary dna (cdna) coding for group 22 allergen of d. farinae (der f 22) from china was cloned, sequenced, and expressed successfully. | 2015 | 26096916 |
| solanum tuberosum l. cv jayoung epidermis extract inhibits mite antigen-induced atopic dermatitis in nc/nga mice by regulating the th1/th2 balance and expression of filaggrin. | solanum tuberosum l. cv jayoung (jy) is a potato with dark purple flesh and contains substantial amounts of polyphenols. in this study, we evaluated the therapeutic effects of s. tuberosum l. cv jy in a mouse model of dermatophagoides farinae body (dfb)-induced atopic dermatitis (ad). the ethanol extract of the peel of jy (epj) ameliorated dfb-induced dermatitis severity, serum levels of immunoglobulin e (ige) and thymus and activation-regulated chemokine. histological analysis of the skin also ... | 2015 | 26102094 |
| effect of solar irradiation on serum specific immunoglobulin e to house-dust mite. | the relationship between sensitization to dermatophagoides species and solar irradiation, as reflected by vitamin d, remains elusive. | 2016 | 26108070 |
| effects of the recombinant allergen rder f 2 on neuro-endocrino-immune network in asthmatic mice. | severe and life-threatening side effects can occur in patients receiving allergen-specific immunotherapy (sit), and recombinant allergens made from cdna have been used in clinical trials for ten years and appear promising for sit. the aim of this study is to explore the effects of the recombinant allergen der f 2 (the group 2 allergen from dermatophagoides farinae) on the neuro-endocrino-immune network in asthmatic mice. twenty-eight mice were divided into four groups - a, b, c and d. to induce ... | 2014 | 26155138 |
| proteomic and immunological identification of two new allergens from silkworm (bombyx mori l.) pupae. | this study explored food allergy caused by eating silkworm (bombyx mori l.) pupae, a traditionally accepted food and animal feed in east and southeast asia, and identified two new allergens by proteomic and immunological methods. proteins isolated from silkworm pupae were separated by two-dimensional gel electrophoresis (2-de); pooled sera from patients allergic to silkworm pupa proteins were used to detect immunoglobulin e (ige)-binding proteins by western blotting, and allergens specific for s ... | 2015 | 26155181 |
| the clinical relevance of various hypersensitivity tests in patients with atopic dermatitis as assessed by their history, scorad changes, and number of days with need of anti-inflammatory treatment. | immediate and delayed hypersensitivity reactions can play a role in the pathogenesis of atopic dermatitis (ad). we tested 71 patients (median age 5 years) with ad for hypersensitivity to grass and birch pollen, dermatophagoides pteronyssinus, and dermatophagoides farinae using atopy patch test (apt), skin prick test (spt), and specific ige measurement. the sensitivity (se) and specificity (sp) of the tests were calculated on the basis of personal history of ad exacerbation, clinical ad score (sc ... | 2015 | 26155366 |
| correlations between allergen-specific ige serum levels in patients with ocular allergy. | to evaluate ocular allergies in patients at the hospital do servidor publico estadual de sao paulo (hspe) and the correlations with serum allergen-specific immunoglobulin e levels. | 2015 | 26165789 |
| immunopotentiator from pantoea agglomerans prevents atopic dermatitis induced by dermatophagoides farinae extract in nc/nga mouse. | pantoea agglomerans lps (immunopotentiator from pantoea agglomerans 1: ip-pa1) has been reported to have anti-inflammatory effects in in vitro and in vivo models. the aim of the present study was to investigate the effects of orally-administered ip-pa1 on atopic dermatitis (ad) symptoms induced by dermatophagoides farinae body extract (dfe) in nc/nga mice. | 2015 | 26168493 |
| variation in allergen content in sublingual allergen immunotherapy with house dust mites. | allergen immunotherapy is a treatment modality which can be applied using different vaccines. the aim of this study was to quantify and compare the allergen content of different house dust mites (hdm)' sublingual treatments and to review the evidence on their efficacy. | 2015 | 26185961 |
| [study on the efficacy and safety of sublingual immunotherapy with standardized dermatophagoides farinae drops for allergic rhinitis]. | to evaluate the efficacy and safety of the sublingual immunotherapy with dermatophagoides farinae drops on patients with allergic rhinitis. | 2015 | 26201187 |
| association of serum 25-hydroxyvitamin d with serum ige levels in korean adults. | studies about the association between vitamin d and allergic disease and the immune-modulatory function of vitamin d have increased in the recent years. however, not enough studies have been conducted for concrete conclusion about the association vitamin d and allergy. we investigate the association between serum immunoglobulin e (ige) and serum 25-hydroxyvitamin d (25(oh)d) levels in korean adults. | 2016 | 26209260 |
| sick building syndrome (sbs) among office workers in a malaysian university--associations with atopy, fractional exhaled nitric oxide (feno) and the office environment. | there are few studies on sick building syndrome (sbs) including clinical measurements for atopy and fractional exhaled nitric oxide (feno). our aim was to study associations between sbs symptoms, selected personal factors, office characteristics and indoor office exposures among office workers from a university in malaysia. health data were collected by a questionnaire (n=695), skin prick test (spt) (n=463) and feno test (n=460). office settled dust was vacuumed and analyzed for endotoxin, (1,3) ... | 2015 | 26225741 |
| vaccination with different doses of dermatophagoides farinae in a mouse model of allergic asthma. | the efficacy of vaccination with different doses of a vaccine has not been clarified. the purpose of this study was to investigate the relationship between the doses of purified house dust mite allergen, and allergic airway inflammation and airway reactivity in a mouse model of allergic asthma. | 2015 | 26226406 |
| cross‑reactivity between group-5 and -21 mite allergens from dermatophagoides farinae, tyrophagus putrescentiae and blomia tropicalis. | group-5 and group-21 allergens, produced by house dust mites and storage mites are 36.6-55.8% identical in their sequences and are recognized by at least 50% of immunoglobulin (ig)e from the sera of individuals allergic to dust mites. in the present study, recombinant group-5 and ‑21 allergens from three mite species, dermatophagoides farinae (rder f 5 and 21), tyrophagus putrescentiae (rtyr p 5 and 21), and blomia tropicalis (rblo t 5 and 21), were purified from escherichia coli, and the ige re ... | 2015 | 26238285 |
| [type i hypersensitivity to nocturnal lepidoptera in a costa rican allergic population]. | allergic patients are routinely tested for various allergens including molds, food, pollen, cockroaches and house dust mites; however, there are patients who present allergy symptoms but show negative results in prick tests with the available allergens. | 2017 | 26239328 |
| clinical characteristics, treatments, and prognosis of atopic eczema in the elderly. | atopic eczema (ae) in the elderly is gradually increasing and has been added to the classification of ae in recent years. this investigation retrospectively analyzed 60 patients with elderly ae. among the clinical characteristics, a male predominance, existence of several patterns of onset and clinical course, and associations with immunoglobulin (ig)e-allergic-status and asthmatic complication were observed. the highest positive-rate and positive-score for serum-specific ige against dermatophag ... | 2015 | 26239460 |
| effect of high-dose sublingual immunotherapy on respiratory infections in children allergic to house dust mite. | allergic rhinitis is characterized by eosinophil inflammation. allergic inflammation may induce susceptibility to respiratory infections (ri). house dust mite (hdm) sensitization is very frequent in childhood. allergen immunotherapy may cure allergy as it restores a physiologic immune and clinical tolerance to allergen and exerts anti-inflammatory activity. | 2015 | 26240793 |
| [percentage of th17 cells in spleen and il-17 level in bronchoalveolar lavage fluid in dermatophagoides farinae allergic asthma mice]. | to detect the percentage of th17 cells in spleen and il-17 level in bronchoalveolar lavage fluid in dermatophagoides farinae allergic asthma mice. | 2015 | 26245125 |
| [expression, purification and bioinformatics analysis of β-hexosaminidase of dermatophagoides farinae]. | the dna fragment encoding β-hexosaminidase was synthesized, and cloned into pet-28a vector. the constructed plasmid pmd18-t-β-hexosaminidase was transformed into e. coli top 10 and followed by expression of the protein induced by iptg. sds-page result showed that the relative molecular mass of the recombinant protein was about m, 55 000. the full length of β-hexosaminidase gene was 1 410 bp. bioinformatics analysis revealed that β-hexosaminidase was composed with 469 amino acid residues with a c ... | 2015 | 26245133 |
| berberine reduce allergic inflammation in a house dust mite allergic rhinitis mouse model. | berberine (ber), used widely as an antibacterial, antifungal, and anti-inflammatory drug, has long been used as a gastrointestinal remedy in chinese traditional medicine. recent reports have suggested that ber suppresses th17 responses that was mediated by direct actions on t cells and thymic stromal lymphopoietin production in primary mast cells. it has been suggested that ber may be useful in treating allergic response. the purpose of this study was to assess the effects of ber treatment on al ... | 2015 | 26275466 |
| fractional exhaled nitric oxide (feno) among office workers in an academic institution, malaysia--associations with asthma, allergies and office environment. | there are few studies on fractional exhaled nitric oxide (feno) and respiratory symptoms among adults in tropical areas. the aim was to study associations between feno and selected personal factors, respiratory symptoms, allergies, office characteristics and indoor office exposures among office workers (n = 460) from a university in malaysia. | 2016 | 26300213 |
| expression, purification and characterization of der f 27, a new allergen from dermatophagoides farinae. | the house dust mite (hdm), dermatophagoidesfarinae (d. farina), is one of the most important indoor allergen sources and a major elicitor of allergic asthma; itscharacterization is important in the diagnosis and immunotherapy of mite allergen-relevant diseases. this study aims to characterize a novel allergen, the d. farinae-derived serpin (der f 27). in this study, the total rna of d. farinae was extracted, and the der f 27 gene was cloned and expressed. the allergenicity of recombinant der f 2 ... | 2015 | 26328010 |
| characterization of der f 29, a new allergen from dermatophagoides farinae. | more than 30 allergens have been identified from dermatophagoides farina (d. farina), which is one of the main species of house dust mites. the mite allergens are an important factor contributing to allergic disease in the world. as the detection and identification of new allergens is critical for the diagnosis or treatment of allergic diseases, we sought to characterize the profilin of d. farina (der f 29) in this study. the results showed that 21% of allergic patients displayed positive result ... | 2015 | 26328014 |
| toxoplasma gondii infection suppresses house dust mite extract-induced atopic dermatitis in nc/nga mice. | toxoplasma gondii (t. gondii) is an obligate intracellular protozoan parasite that infects humans and animals via congenital or postnatal routes, and it is found worldwide. modulation of the immune system by parasite infection is proposed to suppress allergic inflammation. growing evidences have shown that interleukin (il)-10-producing regulatory b cells (b(regs)) and cd4+cd25+foxp3+ regulatory t cells (t(regs)) induced by parasite infection play a critical role in allergic or autoimmune disease ... | 2015 | 26333702 |
| efficacy evaluation of a pollen blocker cream against dust-mite allergy: a multicenter, randomized, double-blind, placebo-controlled crossover trial. | to further evaluate the efficacy and safety of a pollen blocker cream against dust-mite allergy. | 2015 | 26358336 |
| sensitization rates for various allergens in children with allergic rhinitis in qingdao, china. | the aim of this study was to determine the prevalence of sensitization to common allergens in children with allergic rhinitis (ar) living in qingdao, china. we conducted a retrospective analysis for ar cases, who underwent skin prick tests (spt) in qingdao. a total of 2841 children with ar qualified for the inclusion criteria (age 3-5 years: 1500 children; age 6-12 years: 1341 children). the most common inhaled allergens to which the ar children were sensitive were dermatophagoides pteronyssinus ... | 2015 | 26371014 |
| repetitive immunoassay with a surface acoustic wave device and a highly stable protein monolayer for on-site monitoring of airborne dust mite allergens. | this work describes a sensor to be incorporated into the on-site monitoring system of airborne house dust mite (hdm) allergens. a surface acoustic wave (saw) device was combined with self-assembled monolayers of a highly stable antibody capture protein on the saw surface that have high resistance to ph change. a sandwich assay was used to measure a hdm allergen, der f 1 derived from dermatophagoides farinae. capture antibodies were cross-linked to a protein g based capture layer (orla85) on the ... | 2015 | 26378678 |
| chlorella vulgaris attenuates dermatophagoides farinae-induced atopic dermatitis-like symptoms in nc/nga mice. | atopic dermatitis (ad) is a chronic and inflammatory skin disease that can place a significant burden on quality of life for patients. ad most frequently appears under the age of six and although its prevalence is increasing worldwide, therapeutic treatment options are limited. chlorella vulgaris (cv) is a species of the freshwater green algae genus chlorella, and has been reported to modulate allergy-inducible factors when ingested. here, we examined the effect of cv supplementation on ad-like ... | 2015 | 26404252 |
| [positive allergens in children with different allergic diseases]. | to investigate the major allergens in children with different allergic diseases, and to provide theoretical evidence for the clinical prevention, diagnosis, and treatment of allergic diseases in children. | 2015 | 26412169 |
| house dust mite sublingual immunotherapy is safe in patients with mild-to-moderate, persistent asthma: a clinical trial. | the safety of allergen immunotherapy (ait) in asthma has not always been sufficiently documented; accordingly, fear of asthma exacerbations has made physicians somewhat reluctant to prescribe ait in this context. in a double-blind, placebo-controlled, randomized clinical trial, house dust mite (hdm) sublingual ait was found to be efficacious in moderate, persistent asthma. the trial's safety results are now reported in detail. | 2016 | 26465232 |
| the potential for a blood test for scabies. | scabies afflicts millions of people worldwide, but it is very difficult to diagnose by the usual skin scrape test, and a presumptive diagnosis is often made based on clinical signs such as rash and intense itch. a sensitive and specific blood test to detect scabies would allow a physician to quickly make a correct diagnosis. | 2015 | 26492406 |
| studies on the occurrence, identification and control of house dust mites at rural houses of shebin el-kom locality, egypt. | the present study was conducted at elkom elakhdar village, shebin el-kom, menoufia governorate along 2012 year seasons, to calculate and identify the species composition and the occurrence frequency of the extracted dust mites collected from three building ages at rural houses, as well as to determine the toxicity limits of different concentrations of three plant essential oils against two species of the family pyroglyphidae the main causal of allergy to humans. the obtained results revealed tha ... | 2015 | 26506648 |
| [the effect research of specific immunotherapy of allergic rhinitis and allergic rhinitis combined bronchial asthma]. | to study the therapeutic effects of the specific immunotherapy (sit) on allergic rhinitis and allergic rhinitis combined bronchial asthma. methed: all patients were classified into allergic rhinitis group (ar group) with 32 patients and allergic rhinitis combined bronchial asthma group (ar+ba group) with 32 patients. another health control group with 32 cases was designed as well. the allergens,symptom scores and therapeutic effects of the former two-group patients were analysis, and the serums ... | 2015 | 26513998 |
| allergen stabilities and compatibilities in immunotherapy mixtures that contain cat, dog, dust mite, and cockroach extracts. | indoor allergen mixtures that contain cat, dog, dust mite, and cockroach extracts are commonly used in allergy clinics for subcutaneous immunotherapy, but product-specific stabilities and mixing compatibilities in these complex patient formulas have not been determined. | 2015 | 26522255 |
| cloning, expression, purification, characterization, crystallization and x-ray crystallographic analysis of recombinant der f 21 (rder f 21) from dermatophagoides farinae. | dermatophagoides farinae is one of the major house dust mite (hdm) species that cause allergic diseases. n-terminally his-tagged recombinant der f 21 (rder f 21), a group 21 allergen, with the signal peptide truncated was successfully overexpressed in an escherichia coli expression system. the purified rder f 21 protein was initially crystallized using the sitting-drop vapour-diffusion method. well diffracting protein crystals were obtained after optimization of the crystallization conditions us ... | 2015 | 26527267 |
| pharmacodynamic and pharmacokinetic evaluation of house dust mite sublingually administered immunotherapy tablet in the treatment of asthma. | sublingual immunotherapy (slit) for house dust mite (hdm) allergy has an evidence of efficacy demonstrated by meta-analyses, but marked differences are reported between the various slit products. the standardized quality (sq) hdm sublingual tablet containing dermatophagoides pteronyssinus and dermatophagoides farinae in a 1:1 ratio (mk-8237) is a qualitative advance for slit products. | 2015 | 26565665 |
| house dust mites possess a polymorphic, single domain putative peptidoglycan d,l endopeptidase belonging to the nlpc/p60 superfamily. | a 14 kda protein homologous to the γ-d-glutamyl-l-diamino acid endopeptidase members of the nlpc/p60 superfamily has been described in dermatophagoides pteronyssinus and dermatophagoides farinae but it is not clear whether other species produce homologues. bioinformatics revealed homologous genes in other sarcopteformes mite species (psoroptes ovis and blomia tropicalis) but not in tetranychus urticae and metaseiulus occidentalis. the degrees of identity (similarity) between the d. pteronyssinus ... | 2015 | 26566476 |
| the effects of house dust mite sublingual immunotherapy in patients with allergic rhinitis according to duration. | the safety and efficacy of sublingual immunotherapy (slit) have been demonstrated in the recent 2 decades. however, the data is still mixed regarding the efficacy of house dust mite (hdm) slit. the objective of this work was to evaluate the different clinical efficacy slit in patients with allergic rhinitis (ar) according to different durations of treatment. | 2016 | 26575696 |
| comparison of living and bedrooms in terms of house dust mites in the province of erzincan, turkey. | the most important factors in development of symptoms such as allergic asthma, rhinitis, conjunctivitis, and dermatitis in atopic persons are the allergens of house dust mites. the objective of this study was to compare living rooms and bedrooms, and woolen and spring mattresses in terms of the number and species of mites in houses in the province of erzincan, turkey. in total, 74 dust samples were collected from living rooms and bedrooms of 37 randomly selected houses from various districts of ... | 2016 | 26586534 |
| effect of acer tegmentosum bark on atopic dermatitis-like skin lesions in nc/nga mice. | atopic dermatitis (ad) is a chronic and relapsing inflammatory condition characterized by pruritic and eczematous skin lesions that requires safe and effective pharmacological therapy. the bark of acer tegmentosum maxim trees has been used in korean folk and traditional medicine to treat abscesses, surgical bleeding, liver diseases, and ad. | 2016 | 26619913 |
| characterization of a new subtype of allergen in dermatophagoides farinae-der f 28. | house dust mites (hdms) are the major sources of indoor allergens which induce asthma, dermatitis, rhinitis, and some other allergic diseases. close to 30 sub-allergens have been identified. | 2015 | 26623108 |
| [factors associated with the presence of allergen-specific ige responses in asthma patients who had no ige responses detectable by mast-26]. | to elucidate the characteristics of patients with asthma who have specific ige responses to inhaled allergens detected by immunocap, which is not detectable by mast-26. | 2015 | 26657911 |
| sero-prevalence study of ige responses to allergens from malaysian house dust (hdm) and storage mites (sm). | allergens of dermatophagoides and blomia species are well-characterized but not for other species. this study was conducted to determine the prevalence of allergic sensitization to house dust (hdm) and storage mites (sm). one hundred adult subjects (aged ≥ 18) were recruited. the mite specific ige of all allergic subjects were higher compared with healthy subjetcs despite being not statistically significant except for d. farinae and g. malaysiensis. the mean serum ige levels against hdm and sm f ... | 2015 | 26695214 |
| [onset time and efficacy of sublingual immunotherapy with dermatophagoides farinae drops in children with allergic rhinitis]. | to investigate the onset time and efficacy of sublingual immunotherapy (slit) with dermatophagoides farinae drops in children with house dust mites (hdm)-induced allergic rhinitis (ar). | 2015 | 26696197 |