Publications

parkinsonism-plus syndromes.		2009	2657411
[technical methods and hydrogeological aspects of in situ sanitation measures in soil and groundwater areas].	the contribution deals in general with the following aspects of remediation processes: --hydrogeological parameters --microbiological and engineering parameters --engineering conceptions of biological in situ remediations --analytical aspects and monitoring.	2008	2658026
surgery and adjuvant chemotherapy for gastric cancer.	a review has been made of the results of surgical treatment of 8,000 cases of gastric cancer treated at the cancer institute hospital, tokyo, between 1946 and 1986. resectability was 89.6%, and operative mortality 1.9%. the five-year survival rate was 37.4% for all cases, 59.4% for patients with curative surgery, and 5.0% for those with non-curative surgery. the curative rate improved more than twofold over 41 years among the patients with curative gastrectomy. no one survived more than five yea ...	2009	2659483
cytoskeletal proteins including myofilaments in human tumors.		1989	2660368
[the occurrence and significance of chlamydia psittaci and coxiella burnetii in dogs and cats. a study of the literature].	with this review of the literature it is demonstrated that not only infections with chl. psittaci and c. burnetii do occur in dogs and cats in the federal republic of germany but also clinical diseases caused by these agents may occur. especially in diseases with uncharacteristic symptoms both bacteria have to be taken into consideration as causative agents. since both agents cause zoonotic infections a correct diagnosis is of special importance, especially if the owner of a diseased dog or cat ...	1989	2662958
rickettsial diseases.	the rickettsioses have several unifying features. arthropod vectors are the common means of transmission. fever, headache, myalgias, and the characteristic eruption (except in q fever and ehrlichioses) are the hallmarks of the clinical presentation. the diseases share a common pathogenesis, namely, vasculitis, and treatment uniformly consists of tetracycline or chloramphenicol. distinguishing aspects of these processes include the multitude of different reservoirs, the progression of the rash, a ...	1989	2665989
zidovudine-induced fever.	zidovudine (3'-azido-3'deoxythymidine, azt, retrovir) is the first antiretroviral drug to demonstrate clinical efficacy for symptomatic human immunodeficiency virus infection. in a large, placebo-controlled trial, nausea and hematologic toxicity, but not fever, occurred more frequently in zidovudine- than in placebo-treated patients. however, in an open label study, fever severe enough to halt zidovudine administration occurred in 10% of 70 acquired immune deficiency syndrome (aids) patients rec ...	1989	2666640
[distribution of t cell subsets and dr antigen positive t cells in peripheral blood and in intestinal mucosa of inflammatory bowel disease].	the absolute number of t cell subsets and the rate of t cell dr antigen expression in the peripheral blood and the intestinal mucosa in ibd patients were compared with those in healthy normal controls by two color analysis. the methods used here were flow cytometry for the peripheral blood and immunohistological fluorescent staining for the intestinal mucosa. in peripheral blood lymphocyte (pbl), helper (cd4+ leu8-) t cells increased in ulcerative colitis (uc), whereas suppressor (cd8+ cd11+) t ...	2008	2666695
[distribution of t cell subsets and dr antigen positive t cells in peripheral blood and in intestinal mucosa of inflammatory bowel disease].	the absolute number of t cell subsets and the rate of t cell dr antigen expression in the peripheral blood and the intestinal mucosa in ibd patients were compared with those in healthy normal controls by two color analysis. the methods used here were flow cytometry for the peripheral blood and immunohistological fluorescent staining for the intestinal mucosa. in peripheral blood lymphocyte (pbl), helper (cd4+ leu8-) t cells increased in ulcerative colitis (uc), whereas suppressor (cd8+ cd11+) t ...	2008	2666695
management of orbital blow-out fractures. case reports and discussion.	blow-out fractures are fractures of the orbital floor or medial wall that occur as a consequence of blunt trauma. impact increases the intraorbital pressure, forcing the nondistensible orbital contents through the orbital floor. the fracture is commonly caused by impact from a baseball or tennis ball. however, any blunt trauma to the orbit, as from a knee or elbow, can result in a blow-out fracture. the characteristic clinical findings include double vision, a sunken globe, and numbness in the d ...	2008	2667379
[immunohistochemical analysis of hormonal receptors in cancer of the breast. current evaluation].		2009	2667531
biologically active casein peptides implicated in immunomodulation.	maternal milk should not only be considered as a nutrient, but also as a protecting agent against aggressions from the neonate's new environment. breast-feeding facilitates transmission of a passive immunity by multifunctional factors which have a direct effect on the neonate's resistance to bacterial and viral infections. among these factors are the main milk proteins, the caseins: during enzymic digestion of human and bovine caseins, immunomodulating peptides are released. corresponding synthe ...	1989	2668358
titration of coxiella burnetii in buffalo green monkey (bgm) cell cultures.	titration of coxiella burnetii, strain nine mile, phase i, and strain frankfurt, phase ii, in buffalo green monkey (bgm) cover slip cell cultures yielded reproducible infectivity titers after centrifugation of infected cell cultures (3000 g, 30 min, 37 degrees c) and a subsequent 4-day incubation at 37 degrees c in minimal essential medium (mem). compared to other titration procedures (plaque assays, titration in embryonated chicken eggs), this technique proved to be fast, less laborious and eco ...	1989	2669791
spontaneous endotracheal tube extubation in infants and children.		2009	2670610
the kansas medical society membership directory 1989.		2009	2671457
interleukin-1 potentiates granulopoiesis and thrombopoiesis by producing hematopoietic factors in vivo.	in vivo administration of recombinant human interleukin-1 beta (rhu il-1 beta) selectively enhanced the recovery from granulocytopenia and thrombocytopenia caused by whole body irradiation, in a dose dependent manner. since il-1 itself in vitro had no colony-stimulating activity (csa), we studied whether il-1 can produce hematopoietic factors in vivo, which in turn will promote granulopoiesis and thrombopoiesis. serum from il-1 injected mice showed marked granulocyte/macrophage csa (gm-csa), but ...	1989	2671565
[the gray rat (rattus norvegicus) as a carrier of infectious causative agents in siberia and the far east].	literary data and antiplague institutions' reports demonstrate that norway rats carry over 24 nosological forms and groups of infectious diseases: plague, tularemia, pseudotuberculosis, intestinal yersiniosis, salmonellosis, erysipeloid, listeriosis, leptospirosis, pasteurellosis, brucellosis, dysentery, paratuberculosis, hemorrhagic nephroso-nephritis, omsk hemorrhagic fever and q fever, tick-borne and japanese encephalitis, lymphocytic choriomeningitis, tick-borne rickettsiosis and rickettsial ...	1989	2674644
[atypical pneumonias with special reference to prognosis].	the term "atypical pneumonia" was proposed for pneumoniae which ran another course than lobar or bronchopneumoniae. in opposite to the usual bacteriologic pneumoniae in "atypical pneumoniae" there are only seen slight palpatory and auscultatory findings. in spite of high fever there are no tachycardia and no leucocytosis. the diagnosis succeed by x-ray mostly. "atypical pneumoniae" were caused by mycoplasmae, rickettsiae (q-fever), chlamydiae, (ornithosis), viruses (influenca, adenoviruses, cyto ...	1989	2678689
life before medline: myasthenia gravis, muscular dystrophy, and myasthenic myopathy.		2008	2679505
[q fever in guinea-bissau. 1 case].	q fever is seldom reported in west africa. the case of a man returning from guinea bissau who presented an acute lobar pneumonia with fever, headache, hematuria and hepatitis was confirmed by high titers of antibody in phase ii indirect immuno-fluorescence which appeared on the twelfth day of fever. treatment with erythromycin was continued by doxycyclin, and complete resolution of all signs was promptly obtained. coxiella burnetii might thus be responsible of cases of unexplained fever with res ...	1989	2680135
[tolerance and reverse tolerance of nicotine on spontaneous motor activity].	repeated administration of nicotine induces tolerance and/or reverse tolerance of spontaneous motor activity in rodents. these effects of nicotine on the spontaneous motor activity have been shown to be influenced by drug factors (e.g., doses, elapsed time after injection, period of treatment), circadian rhythm, age, sex, strain and species of animals. although nicotinic acetylcholine receptors in the brain participate in the effects of nicotine, the development of tolerance and reverse toleranc ...	1989	2680832
interrelationships between digestive proteolytic activities and production and quantitation of toxins in pseudomembranous colitis induced by clostridium difficile in gnotobiotic mice.	clostridium difficile pathogenicity is related to in vivo production of toxins, and it is of great interest to detect toxins produced in biological samples. several reports have shown that proteases in stools interfere with immunological methods for quantitation of toxin a. the purpose of this work was to estimate the relationship between the proteases and the c. difficile toxins produced in a gnotobiotic mouse model of pseudomembranous cecitis. cecal proteolytic activities hydrolyzed toxin a, a ...	1989	2680988
[lesions of the cardiovascular system in q fever].		1989	2681990
extreme distal migration of premolar in association with an unusual fracture of the mandible.	a case of an unerupted mandibular premolar, discovered as an incidental finding during investigation of a fracture of the mandible, is described. the possible mechanisms and outcome of migrations of such teeth are reviewed.	2008	2682425
phosphoroselenoate oligodeoxynucleotides: synthesis, physico-chemical characterization, anti-sense inhibitory properties and anti-hiv activity.	oligodeoxynucleotides with a phosphorus atom in which one of the non-bridging oxygen atoms is substituted by selenium were prepared and investigated with respect to their antisense properties. a general synthesis of phosphoroselenoate analogs of oligonucleotides is described using potassium selenocyanate as the selenium donor. the compounds, characterized by 31p nmr, were shown to decompose to phosphate with a half-life of ca. 30 days. melting temperatures of duplexes between poly(ra) or poly(ri ...	1989	2682524
[serologic studies of domestic animals for listeriosis, q-fever, and brucellosis in cairo].	first serological investigations among domestic animals (donkey, goat, sheep, swine, dog) and rats (rattus norvegicus) carried out in the surroundings of persons from waste disposal sites in cairo indicate the occurrence of listeriosis, q fever and brucellosis.	1989	2684762
[the phase variation of coxiella burnetii (theory and practice)].		1989	2686315
clinical summary of initial intravenous administration of ioversol.	data from 23 double blind, controlled, parallel-group comparative studies evaluating the intravenous safety, efficacy, and patient tolerance of ioversol were collected. nine open-label studies were evaluated, as well. a small number of side effects that would be considered serious were reported, but resulted in no clinically significant sequelae, (e.g., angina, bradycardia, vasovagal response, and hypoxia). there were no significant changes in vital signs related to the use of the drug. these st ...	2009	2687195
animal health research in the small ruminant collaborative research support program.	disease is a major constraint in small ruminant production systems in lesser-developed countries throughout the world. animal health projects have been an integral part of the small ruminant collaborative research support program (sr-crsp) from its inception. at the onset, these projects were oriented toward herd health care and veterinary extension activities. later, all the projects developed a sharper focus in that they were directed to more basic studies of infectious disease. diseases curre ...	1989	2687219
hydrophobic grid membrane filter/mug method for total coliform and escherichia coli enumeration in foods: collaborative study.	twenty-four laboratories participated in a collaborative study to validate a hydrophobic grid membrane filter (hgmf) method incorporating the use of 4-methylumbelliferyl-beta-d-glucuronide (mug) for enumeration of total coliform and escherichia coli bacteria in foods by comparing its performance against the aoac 3-tube mpn method (46.013-46.016). raw milk, raw ground poultry, whole egg powder, cheese powder, and ground black pepper were included in the study. the total coliform methods did not d ...	1989	2687225
mast cell-mediated inflammation in asthma.		2009	2688493
computer simulations of globular protein folding and tertiary structure.	in summary, although a large number of disparate techniques have been applied to predict the tertiary structure of globular proteins from their amino acid sequence, the solution is not yet at hand. methodologies for predicting the conformation of constrained, small protein fragments appear to be successful. as the size of the system increases, the level of detail of the treatment decreases; approaches that employ very detailed potentials appear to be limited to about 30-40 residues. although thi ...	2008	2688673
isolation of constitutive mutations affecting the proline utilization pathway in saccharomyces cerevisiae and molecular analysis of the put3 transcriptional activator.	the enzymes of the proline utilization pathway (the products of the put1 and put2 genes) in saccharomyces cerevisiae are coordinately regulated by proline and the put3 transcriptional activator. to learn more about the control of this pathway, constitutive mutations in put3 as well as in other regulators were sought. a scheme using a gene fusion between put1 (s. cerevisiae proline oxidase) and galk (escherichia coli galactokinase) was developed to select directly for constitutive mutations affec ...	1989	2689861
clinical aspects and prevention of q fever in animals.	the natural reservoir of coxiella burnetii encompasses many free-living vertebrates but the major risk of human infection arises through contact with infected ruminant livestock and their contaminated products. the organism has a remarkable affinity for the ruminant placenta and mammary gland but the great majority of naturally-occurring infections are asymptomatic. however, the potential of c. burnetii to cause abortion has been demonstrated experimentally and observed in the field while more r ...	1989	2691272
q-fever and autoimmunity.	to determine the incidence and the clinical significance of two autoimmune markers in q-fever (smooth muscle antibodies, cold agglutinins).	1989	2691275
[treatment of pneumonia caused by legionella, mycoplasma, chlamydiae and rickettsia using ofloxacin].	to asses the efficacy and the safety of ofloxacin as therapy of pneumonia caused by intracellular pathogens, 35 patients were studied (26 male, 9 female, mean age: 52.5 +/- 16.6 years). causative pathogens were chlamydia psittaci (n = 13), legionella pneumophila (n = 10), mycoplasma pneumoniae (n = 7) and coxiella burnetii (n = 5). ofloxacin was administered orally in 32 cases (200 mg b.i.d. in 80% of cases) and by i.v. route in 3 cases. all patients were cured without any side effects. in concl ...	1989	2691969
[null alleles of yeast sup1 and sup2 genes: interaction with cytoplasmic determinants].		1989	2693034
failla memorial lecture. the search for critical cellular targets damaged by heat.		2009	2694212
[the biological properties of rickettsia burnetii isolated in the northwestern ukrainian ssr].	biological properties of two strains of the burnet rickettsia isolated in the natural foci of the q fever in the northwest of the ukrainian ssr are studied. strain "gishin" was characterized by high virulence for the laboratory animals and considerably exceeded the strain "politsa" in the virulent properties. antigen of phase i prepared from the strain "politsa" was highly active in revealing the corresponding antibodies. the high-sensitive reaction of indirect immunofluorescence has shown the p ...	1989	2695792
[assessment instruments used in rehabilitation].	nowadays the word assessment is commonly used in the field of health, but what aspects does it cover in rehabilitation medicine? this paper presents conceptual and operational approaches to the assessment of patients suffering from functional limitation. these systems of assessment either represent a global approach--considering patients' activities of daily living--or have been specifically elaborated for a category of patients such as those with quadriplegia. however, such instruments pose pro ...	2009	2698393
effect of sodium artesunate on malaria infected human erythrocytes.	oxidative stress in malaria infected human erythrocytes is augmented and the anti-oxidant system is attenuated as compared with normal rbc's. exacerbation of intra-erythrocytic oxidative stress might provide a means to kill the parasites. sodium artesunate (sa), an effective chinese anti-malaria drug, markedly increased the levels of active oxygen species and production of malonyldialdehyde in normal red blood cells and, to a greater extent, in malaria infected red blood cells. sa caused a remar ...	1989	2698476
[how certain is an active bond between a ceramic restoration and dental enamel?].		2008	2700454
[blended ceramic root post caps].		2009	2701608
tuberous sclerosis--another success for magnetic resonance imaging.		2009	2704257
streptococcus pneumoniae endocarditis presenting as an epidural abscess.	streptococcus pneumoniae is an important pathogen in many serious infections, such as pneumonia, sinusitis, and meningitis. it uncommonly causes infective endocarditis and only rarely produces spinal epidural abscesses. this report describes a patient who had pneumococcal infection presenting as an acute epidural abscess and who was subsequently found to have endocarditis. s. pneumoniae was cultured from both blood and abscess material. a high level of clinical suspicion of endocarditis is impor ...	1989	2704929
streptococcus pneumoniae endocarditis presenting as an epidural abscess.	streptococcus pneumoniae is an important pathogen in many serious infections, such as pneumonia, sinusitis, and meningitis. it uncommonly causes infective endocarditis and only rarely produces spinal epidural abscesses. this report describes a patient who had pneumococcal infection presenting as an acute epidural abscess and who was subsequently found to have endocarditis. s. pneumoniae was cultured from both blood and abscess material. a high level of clinical suspicion of endocarditis is impor ...	1989	2704929
chronic hip pain and limp in a 3-year-old girl.		2008	2704930
chronic hip pain and limp in a 3-year-old girl.		2008	2704930
q fever pneumonia presenting as an eosinophilic pleural effusion.		1989	2705155
the effect of n-3 polyunsaturated fatty acids on lipids, haemostasis, neutrophil and monocyte chemotaxis in insulin-dependent diabetes mellitus.	insulin-dependent diabetes mellitus (iddm) is associated with an increased risk of coronary artery disease (cad). there is some evidence that polyunsaturated fatty acids of the marine n-3 type (n-3 pufa's) may offer protection against cad. we have studied the effect of short-term dietary supplementation with n-3 pufas on lipids, haemostasis, neutrophil and monocyte chemotaxis in 10 patients with iddm. the patients were given 4 g daily of n-3 pufas (fish oil) for 6 weeks and were investigated bef ...	2008	2706043
prenatal ontogenesis of pro-opiomelanocortin in the mouse central nervous system and pituitary gland: an in situ hybridization and immunocytochemical study.	pro-opiomelanocortin (pomc) mrna detected by in situ hybridization and pomc/acth (adrenocorticotropin)-containing neurons detected by immunocytochemistry were first observed in the presumptive arcuate nucleus of embryonic mouse brain on gestational day 10.5 (e10.5). immunostained fibers were also evident on e10.5 in the lateral and dorsal diencephalon. in these areas, a dense network of processes developed by e11.5 and extended into the mesencephalon. fibers were detected in the myelencephalon a ...	1989	2706773
elastic and ultimate properties of acrylic bone cement reinforced with ultra-high-molecular-weight polyethylene fibers.	a study of the fracture behavior of poly-(methyl methacrylate) (pmma) bone cement reinforced with short ultra-high-molecular-weight polyethylene (spectra 900) fibers is presented. linear elastic and nonlinear elastic fracture mechanics results indicate that a significant reinforcing effect is obtained at fiber contents as low as 1% by weight, but beyond that concentration a plateau value is reached and the fracture toughness becomes insensitive to fiber content. the flexural strength and modulus ...	2009	2708405
q fever pneumonia.	pneumonia is one of several clinical syndromes that results from inhalation of coxiella burnetii. this microorganism, the etiologic agent of "q" (query) fever, infects a wide range of animals and insects. cattle, sheep, goats, and cats are the reservoirs whereby this agent is spread to humans. high concentrations of c burnetii are present in the placenta and at parturition, the organism is shed into the environment to be inhaled by humans. following an incubation period that ranges from four to ...	1989	2711056
effects of inducers of differentiation on protein kinase c and cmp-n-acetylneuraminic acid:lactosylceramide sialyltransferase activities of hl-60 leukemia cells.	exposure of hl-60 leukemia cells to either 12-o-tetradecanoylphorbol-13-acetate (tpa), dimethylsulfoxide (dmso), exogenous gangliosides gm3, gm1, or bovine brain ganglioside mixture (bbg) resulted in a marked inhibition of the growth of cells. the order of the inhibitory potency was tpa greater than gm3 greater than dmso greater than bbg greater than gm1. in contrast, sulfatides were without effect on cellular replication. treatment of hl-60 cells with tpa or gm3 induced differentiation along th ...	1989	2715723
[treatment of atypical pneumonia with josamycin].	in the present study the clinical efficacy and tolerance of josamycin (1 g every 12 hours) was prospectively evaluated for the empirical therapy of patients below 70 years with community acquired pneumonia of atypical presentation (ap), without respiratory failure, radiological cavitation or risk factors of pharyngeal colonization by gram-negative bacilli. during a 28-month period 168 patients adequate for the study were included. the etiological diagnosis was established in 56 cases (33.3%); in ...	1989	2716415
[unusual clinical and radiologic manifestations in q fever].		1989	2717797
complications of cardiac catheterization and angiography in patients with valvular heart disease. va cooperative study on valvular heart disease.	complications were surveyed prospectively in 2,029 catheterizations performed on 1,483 patients from the 13 centers participating in the va cooperative study on valvular heart disease. complications were reported in 6.9% of 1,559 preoperative procedures of which 2.6% were major and 0.2% fatal. clinical predictors of complications were hypertension and the precatheterization diagnosis of aortic stenosis. nevertheless, patients with aortic stenosis successfully tolerated left ventriculography, whi ...	2009	2720763
[effect of transportation noise on the status of the cardiovascular system of the population].	the results of a multipronged study of noise effect on the state of the cardiovascular system of the urban population are presented. the study of regular noise effect on various population groups has been conducted under natural and laboratory conditions. a complex of appropriate investigation techniques has been used. the population of noise-exposed regions has higher rates and more distinct forms of disorders in myocardium, vessel elasticity, hemodynamics, extracardial regulation and higher ri ...	2006	2721990
osteoarticular infection due to coxiella burnetii.		1989	2723460
how accurate are faculty evaluations of clinical competence?	to determine the degree and sources of variability faculty evaluations of residents for the american board of internal medicine (abim) clinical evaluation exercise (cex).	2009	2723833
the ability of mononuclear cells to coagulate blood in response to coxiella burnetii.	endocarditis is a rather frequent complication of q fever caused by coxiella burnetii. we examined the ability of phase i (virulent) or phase ii (avirulent) c. burnetii to coagulate blood in the presence of human blood mononuclear cells in vitro. after incubation for 4 h, virulent phase i c. burnetii was an effective stimulant for mononuclear cells. since this interaction is a potent trigger of blood coagulation through the extrinsic pathway, it could be responsible for the local deposition of f ...	1989	2724327
induction of experimental thyroid dysfunction in rats with implantable pellets of thyroxine or propylthiouracil.	subcutaneously implanted pellets containing the thyroid hormone thyroxine or the thyrotoxic agent propylthiouracil were used to induce hyper- or hypothyroidism in rats. the results obtained were compared to those produced by daily subcutaneous injection of these substances. the thyroxine pellets caused substantial elevation of serum thyroxine concentrations for at least 25 days, whereas the propylthiouracil pellets caused a pronounced decrease of serum thyroxine concentrations. changes in heart ...	1989	2724991
[adverse effects of drugs and computerized registries--a threat or a possibility?].		2009	2725139
effects of perinatal exposure to aspartame on rat pups.	possible effects of perinatal exposure to l-aspartyl-l-phenylalanine methyl ester (aspartame) on rat pups were investigated. adult female rats, and later their pups, were exposed, via their drinking water, to aspartame (0.007%, 0.036%, 0.18% or 0.9% w/v) or phenylalanine (0.45% w/v) for 12 days prior to conception until the pups were 38 days old. control rats were given plain water. the adults exposed to aspartame consumed an average of 14, 68, 347 and 1614 mg/kg/day of aspartame and those expos ...	1989	2725436
prospects for a vaccine against hiv.		1989	2725655
the correlation of electroretinographic and histopathological findings in the eyes of mice infected with the 79a strain of scrapie.	retinal degeneration was produced using the 79a strain of scrapie injected intracerebrally into mice of the mm inbred strain, and studied by electroretinography and light and electron microscopy during the preclinical and clinical phases of the disease. the changes in the electroretinogram (erg), detectable in some mice at 118 days postinjection (d.p.i.), appeared to coincide with the earliest morphological evidence of photoreceptor damage. in the early stages there was a progressive reduction o ...	1989	2725831
desbase, a multiparameter substituent database.		2009	2726828
q fever endocarditis: delay in diagnosis due to an apparent clinical response to corticosteroids.		1989	2729329
breast volume measurement of 598 women using biostereometric analysis.	a study of the volumes of the right and left breasts of 598 subjects was undertaken using biostereometric analysis. this measurement uses close-range stereophotogrammetry to characterize the shape of the breast, and is noncontact, noninvasive, accurate, and rapid with respect to the subject involvement time. using chi-square tests, volumes and volumetric differences between breast pairs were compared with handedness, perception of breast size by each subject, age, and menstrual status. no signif ...	2009	2729845
q fever pneumonia: a review of 164 community-acquired cases in the basque country.	one hundred and sixty four cases of q fever pneumonia are reviewed. coxiella burnetti is responsible for 18.8% of pneumonias acquired in the community in our region with an extremely high seasonal variation. 91% of the cases occur between january and june. 88.5% of the patients are less than 40 yrs of age and 77% are male. the most common clinical symptoms are high fever, cough, cephalalgia and myalgias. 46.5% of the patients have no respiratory symptoms although 34% of the cases report pleural ...	1989	2731605
elevated fibrin d-dimer fragment in sickle cell anemia: evidence for activation of coagulation during the steady state as well as in painful crisis.	the fibrin d-dimer degradation fragment is produced by plasmin degradation of cross-linked fibrin. elevated plasma d-dimer levels indicate increased plasmin degradation of cross-linked fibrin, and are therefore an indirect indication of increased thrombin activity and fibrin formation. with an elisa assay sensitive to plasma d-dimer levels of less than 50 ng/ml, elevated levels of d-dimer were found in 23 of 25 subjects with sickle cell disease tested during the steady state, and in all 21 subje ...	2009	2731776
interferon antibodies in patients with chronic hbv infection treated with recombinant interferon.	in different trials, a total of 46 adults and 12 children suffering from chronic hepatitis b virus (hbv) and who were hbv-dna- and hbeag-positive were treated with recombinant interferon-alpha (rifn alpha)-2a. the interferon was administered intramuscularly in different doses ranging from 1.5 mu to 20 mu/m2 of body surface, two or three times weekly during 4-6 months. specific detection of anti-ifn antibodies by enzymoimmunoassay (eia), radioimmunoassay (ria) and biological assays during treatme ...	1989	2732449
igg and igm responses in high and low antibody-selected lines of chickens.	kinetics of igg and igm as measured by 2-mercaptoethanol-resistant (mer) and susceptible (mes) antibodies to sheep erythrocytes, respectively, were determined as correlated responses in lines of chickens selected for high (ha) and low (la) antibody response to sheep erythrocytes. primary response patterns for total, mer, and mes antibody differed according to the genetic line. total antibody increased rapidly, peaked, and persisted at moderate levels in line ha, whereas both peak and persistency ...	1989	2732455
heterogeneic expression of blood group a and h isoantigens in bladder tumors: association with nuclear volume.	intratumor heterogeneity is a major problem in immunodiagnosis and treatment of carcinomas. to elucidate the well-known heterogeneity in transitional-cell carcinomas of the ability to express blood group abo isoantigens, a stereological estimate of the mean nuclear volume in areas expressing blood group antigens was compared to the estimate from areas of identical pathological grade at which antigen expression was deleted. four microscopic fields were examined from antigen-positive and four from ...	2002	2732458
effect of replacing glucose with lipid on the energy metabolism of newborn infants.	1. indirect calorimetry and primed constant infusion of [u-13c]glucose were combined in 28 appropriate-for-gestational age newborn, parenterally fed infants, in order to measure glucose utilization and glucose oxidation and to estimate lipogenesis from glucose. 2. the infants were randomly allocated to either a group receiving glucose as the non-protein energy source or a group having one-quarter of the glucose energy replaced by intravenous fat. the energy intake (370 kj day-1 kg-1) and protein ...	2008	2736877
effect of replacing glucose with lipid on the energy metabolism of newborn infants.	1. indirect calorimetry and primed constant infusion of [u-13c]glucose were combined in 28 appropriate-for-gestational age newborn, parenterally fed infants, in order to measure glucose utilization and glucose oxidation and to estimate lipogenesis from glucose. 2. the infants were randomly allocated to either a group receiving glucose as the non-protein energy source or a group having one-quarter of the glucose energy replaced by intravenous fat. the energy intake (370 kj day-1 kg-1) and protein ...	2008	2736877
electrocardiographic changes can precede the development of myocardial hypertrophy in the setting of hypertrophic cardiomyopathy.	a comparison was made of electrocardiographic findings in 107 first-degree relatives of patients with hypertrophic cardiomyopathy without any clinical and echocardiographic signs of the disease and 188 healthy persons with a negative family history. a significantly larger number of electrocardiographic signs of left ventricular hypertrophy (p less than 0.05) and abnormal q wave (p less than 0.005) was shown in the group of the relatives. abnormalities of the r wave in v1-3 and of the st-t segmen ...	2009	2737777
angiolymphoid hyperplasia with tissue eosinophilia.	angiolymphoid hyperplasia with eosinophilia is a rare but distinctive clinicopathologic entity. a study of seven cases and review of the literature strongly suggests that both conditions represent a single disease spectrum. the relation of this condition to kimura's disease is controversial. the descriptive term angiolymphoid hyperplasia with tissue eosinophilia is proposed.	2002	2737805
immunocytochemical localization of adrenodoxin in bovine adrenal cortex by protein a-gold technique.	to investigate the intracellular localization of the enzymes that are involved in steroid hormone synthesis, an immunocytochemical study of the distribution of adrenodoxin in cells of the bovine adrenal cortex was carried out by the post-embedding immunostaining method and by immuno-cryoultramicrotomy in combination with the protein a-gold technique. gold particles were seen on the matrix and the inner membrane of all the mitochondria examined, which have typical vesicular or tubulo-vesicular cr ...	1989	2737927
fibrinogen nagoya, a replacement of glutamine-329 by arginine in the gamma-chain that impairs the polymerization of fibrin monomer.	structural studies on a hereditary abnormal fibrinogen, fibrinogen nagoya (takamatsu, j., ogata, k., kamiya, t., koie, k., takagi, t., & iwanaga, s. (1979) thromb. haemost. 42, 78), were performed to identify the abnormality responsible for the impaired polymerization of fibrin monomer. upon sodium dodecyl sulfate-polyacrylamide gel electrophoresis under reducing conditions, fibrinogen nagoya showed the presence of an extra protein band with an apparent molecular weight of 49,500 in addition to ...	2009	2738036
amino acid sequences and disulfide bridges of serine proteinase inhibitors from bitter gourd (momordica charantia linn.) seeds.	three serine proteinase inhibitors, mcti-i, mcti-ii, and mcei-i, were isolated from bitter gourd (momordica charantia linn.) seeds. mcti-i and mcti-ii were inhibitors for trypsin and mcei-i was an elastase inhibitor. their amino acid sequences and the positions of disulfide bridges of mcti-ii were determined to be as follows. (sequence; see text)	2009	2738047
upstream regulatory elements of murine alpha 4-interferon gene confer inducibility and cell type-restricted expression.	we have identified and functionally characterized dna sequences that are required for the inducible and cell-restricted expression of the murine alpha 4-interferon gene. hybrid plasmids in which the alpha 4 promoter region or its 5' deletions were inserted upstream of the cat gene were constructed, and the expression of these hybrid genes was studied in mouse l-cells both in permanent and transient assays with comparable results. inducible expression was not affected by deletions up to -109; how ...	1989	2738062
the aberdeen impedance imaging system.	the aberdeen impedance imaging system is designed to reconstruct 2 dimensional images of the average distribution of the amplitude and phase of the complex impedance within a 3 dimensional region. the system uses the four electrode technique in a 16 electrode split-array. the system hardware consists of task-orientated electronic modules for: driving a constant current, multiplexing the current drive, demultiplexing peripheral voltages, differential amplification, phase sensitive detection and l ...	2009	2742979
enlargement of the pancreatic head in patients with pancreas divisum.	pancreas divisum (pd) is a congenital anomaly present in 6-10% of the population. computed tomography (ct) examinations in eight of 15 patients (53%) with endoscopic retrograde pancreatography (ercp)-proven pd were interpreted as showing enlargement of the pancreatic head. two of these had carcinoma, three had pancreatitis limited to the ventral pancreas, and three were normal. criteria to distinguish nonpathologic enlargement of the pancreatic head due to pd alone from pathologic causes may inc ...	2009	2743193
alternative routes for the establishment of surface polarity during compaction of the mouse embryo.	during the process of compaction, mouse 8-cell blastomeres flatten upon each other and polarize along an axis perpendicular to cell contacts. if the process of flattening is prevented, polarization can still occur, but does so in a lower proportion of cells than for control populations, and without the normal contact-directed orientation. we compared contact-directed and noncontact-directed processes to see if they involve common mechanisms. in nonflattened cells, surface polarization was favore ...	1989	2744237
evidence that the voltage-dependent component in the fertilization process is contributed by the sperm.	to investigate the mechanisms that account for the voltage dependence of fertilization and provide an electrical block to polyspermy, we studied cross-fertilizations between three species of amphibians having different degrees of voltage dependence. anurans, such as the toad bufo japonicus, as well as the primitive urodele hynobius nebulosus, have voltage-dependent fertilization; other urodeles, such as cynops pyrrhogaster, have voltage-independent fertilization (y. iwao, 1989, dev. biol. 134, 4 ...	2009	2744242
serological investigations of the hedgehog (erinaceus europaeus) in styria. 2. report.	from 1975 to 1982 investigations of 64 hedgehogs for anthropozoonoses and infectious diseases were carried out in all regions of styria, austria. the serological investigations revealed positive results against rickettsiosis, (q-fever and rmsf-groups antigen), (ornithosis, toxoplasmosis, listeriosis, against adenoviruses and herpesvirus). other studies by nosek et al. (1967); troger et al. (1976); kaaserer et al. (1976) and stunzner et al. (1976) report on the hedgehog (erinaceus europaeus) as i ...	1989	2744467
[incidence of coxiella burnetii and rickettsiae from the rmsf group in the sub-alpine region in austria].	investigations were carried out on small mammals to determine further distribution of coxiella burnetii and rickettsia rmsf-group in the alpine and sub-alpine regions. in altitudes of 1,200-2,400 m antibodies against clethrionomys glareolus, apodemus flavicollis, sorex alpinus, sorex minutus and microtus agrestis were demonstrated. these findings emphasize that in the entire alpine and sub-alpine regions of austria the occurrence of c. burnetii and rmsf-group rickettsia is to be expected.	1989	2744470
serological investigations of small mammals in waste disposal sites in austria. 2nd report.	in serological investigations of small mammals in waste disposal sites, in austria, antibodies were demonstrated against q-fever, rmsf-rickettsia, listeriosis, tbe (fsme) and west-nile virus.	1989	2744474
the visual field in advanced glaucoma.	for analysis of the morphology of the visual field in advanced glaucoma, we tested 62 eyes of 54 late stage glaucoma patients using program 10-2 on the humphrey field analyzer. the fields, which were already reduced to a small central isle, had mostly typical, asymmetric borders with their largest extend to the temporal lower quadrant and their smallest extend to the upper nasal quadrant. an upper nasal step was very frequent. the boundaries are equivalent to the retinal nerve fiber lines. actua ...	2008	2744955
the visual field in advanced glaucoma.	for analysis of the morphology of the visual field in advanced glaucoma, we tested 62 eyes of 54 late stage glaucoma patients using program 10-2 on the humphrey field analyzer. the fields, which were already reduced to a small central isle, had mostly typical, asymmetric borders with their largest extend to the temporal lower quadrant and their smallest extend to the upper nasal quadrant. an upper nasal step was very frequent. the boundaries are equivalent to the retinal nerve fiber lines. actua ...	2008	2744955
[present state of conservative breast therapy in canada].		2008	2746948
[q fever associated with lobular panniculitis and transient monoclonal gammopathy].		1989	2747336
[pseudoaneurysm of the superficial femoral artery diagnosed preoperatively by magnetic resonance].	a case of pseudoaneurysm of the superficial femoral artery identified preoperatively by magnetic resonance is reported. the number of different parameters and planes covered by the technique permitted an accurate assessment of the site, extent, internal conformation and staging of the thrombotic deposits inside the pseudoaneurysm itself.	2009	2747940
[a new method of heparin therapy: subcutaneous administration... even in pediatric indications!].		2009	2748154
report of montreal collaborative centre biological psychiatry program.		2009	2748855
susceptibility of coxiella burnetii to pefloxacin and ofloxacin in ovo and in persistently infected l929 cells.	the relative lack of efficacy of the antibiotic treatment of chronic q fever endocarditis justifies the further evaluation of the susceptibility of coxiella burnetii to the modern quinolone antibiotics. we evaluated the efficacies of pefloxacin and ofloxacin in controlling the nine mile isolate of c. burnetii by using an embryonated egg assay and persistently infected l929 cells in culture. pefloxacin was effective in controlling the intracellular parasite at a concentration of 50 micrograms per ...	1989	2751278
purification and partial characterization of 1-aminocyclopropane-1-carboxylate synthase from tomato pericarp.	1-aminocyclopropane-1-carboxylate synthase was purified 5000-fold from licl-induced tomato fruit slices by conventional and high-performance liquid chromatography. the final preparation was estimated to be between 25% and 50% pure. two-dimensional gel electrophoresis indicates that 1-aminocyclopropane-1-carboxylate synthase activity is associated with a 45-kda polypeptide, with a pi of 5.8 +/- 0.2. the enzyme is inactivated both by its substrate, s-adenosyl-l-methionine (adomet) and by one of it ...	2009	2753036
phylogenetic diversity of the rickettsiae.	small subunit rrna sequences have been determined for representative strains of six species of the family rickettsiaceae: rickettsia rickettsii, rickettsia prowazekii, rickettsia typhi, coxiella burnetii, ehrlichia risticii, and wolbachia persica. the relationships among these sequences and those of other eubacteria show that all members of the family rickettsiaceae belong to the so-called purple bacterial phylum. the three representatives of the genus rickettsia form a tight monophyletic cluste ...	1989	2753854
acute umbilical sepsis and pilonidal disease.		2009	2754412