Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| consent and the young mother. | 2010 | 2857392 | |
| nalidixic-acid-resistant shigella dysenteriae i. | 1985 | 2858035 | |
| effects of a high-sucrose diet on the development of enzyme-altered foci in chemical hepatocarcinogenesis in rats. | dietary factors can modify metabolic events involved in the initiation, promotion, or progression of tumors. to determine whether a high-sucrose diet has any effect on the development of enzyme-altered foci during the promotion step of chemical hepatocarcinogenesis in rats, 1-day-old sprague-dawley rats were given a single i.p. dose of diethylnitrosamine; controls received an equivalent i.p. volume of 0.9% nacl solution. at 21 days of age, the rats were weaned, segregated by sex, separated in gr ... | 1985 | 2859110 |
| effects of a high-sucrose diet on the development of enzyme-altered foci in chemical hepatocarcinogenesis in rats. | dietary factors can modify metabolic events involved in the initiation, promotion, or progression of tumors. to determine whether a high-sucrose diet has any effect on the development of enzyme-altered foci during the promotion step of chemical hepatocarcinogenesis in rats, 1-day-old sprague-dawley rats were given a single i.p. dose of diethylnitrosamine; controls received an equivalent i.p. volume of 0.9% nacl solution. at 21 days of age, the rats were weaned, segregated by sex, separated in gr ... | 1985 | 2859110 |
| epidemic shiga bacillary dysentery in rangoon, burma, 1984/85. | 1985 | 2861376 | |
| anticholinergic drugs in the treatment of airways disease. | 2010 | 2861843 | |
| evidence against putrescine and polyamines as endogenous mediators of fever. | endogenous concentrations of putrescine, spermidine, spermine and related biosynthetic enzymes were not affected by the administration of bacterial endotoxin and the subsequent development of fever in rabbits. in addition, the febrile response to endotoxin was unaffected either by the ornithine decarboxylase inhibitor, dl-alpha-difluoromethylornithine or by putrescine. these data indicate polyamines are not involved in the development of fever. | 1985 | 2862252 |
| multiresistant shigella infections in bangladesh. | 1985 | 2863461 | |
| immunocytochemical studies of somatostatin neurons in brain. | immunohistochemical studies with antisera to somatostatin have, in many instances, led the way to our present understanding of the peptidergic nervous system. somatostatin was among the first of the hypophysiotropic hormones shown to be contained in diverse neuronal circuits outside of the hypothalamus. for example, somatostatin is found within neurons ranging in location from the cerebral cortex to primary sensory neurons to enteric neurons within the gut wall. somatostatin was also the first n ... | 1985 | 2863929 |
| two distinct toxins active on vero cells from escherichia coli o157. | 1985 | 2864594 | |
| multiresistant shigella dysenteriae type 1. | 1985 | 2865444 | |
| htlv-iii antibody tests and health education. | 2005 | 2870378 | |
| htlv-iii antibody tests and health education. | 2005 | 2870378 | |
| transglutaminase and neuronal differentiation. | during mouse brain maturation cellular transglutaminase specific activity increases 2.5 fold from day 3 to adulthood. a more pronounced increase is seen during morphological differentiation of mouse neuroblastoma cells, where serum withdrawal induces neurite outgrowth concomitant with a 10 fold increase in transglutaminase specific activity. in contrast, non-dividing neuroblastoma cells lacking neurites show only a 1.5 fold increase in enzyme specific activity. transglutaminase activity does not ... | 1986 | 2870428 |
| transglutaminase and neuronal differentiation. | during mouse brain maturation cellular transglutaminase specific activity increases 2.5 fold from day 3 to adulthood. a more pronounced increase is seen during morphological differentiation of mouse neuroblastoma cells, where serum withdrawal induces neurite outgrowth concomitant with a 10 fold increase in transglutaminase specific activity. in contrast, non-dividing neuroblastoma cells lacking neurites show only a 1.5 fold increase in enzyme specific activity. transglutaminase activity does not ... | 1986 | 2870428 |
| integrating treatments in schizophrenia. | schizophrenia is a common and severe illness found throughout the world. onset is usually in adolescence and young adulthood, and many individuals have illness-related impairments for life. schizophrenia assaults the very essence of what is distinctly human. the personality is devastated, subjective experience and thought distorted, and the psychological building blocks of everyday life torn asunder. this article discusses diagnostic and conceptual considerations, pharmacotherapy, and interperso ... | 1986 | 2870478 |
| platelet aggregation caused by carybdea rastonii toxins (crtx-i, ii and iii) obtained from a jellyfish, carybdea rastonii. | the pharmacological mechanisms of platelet aggregation induced by highly toxic proteins (crtx-i, crtx-ii, and crtx-iii) obtained from tentacles of a jellyfish, carybdea rastonii, were investigated. when the partially purified toxin (pcrtx) and crtxs were added to the citrated platelet-rich plasma (prp), aggregation was produced in a concentration-dependent manner. the activity of crtxs was approximately 100 times more potent than pcrtx. the crtxs-induced aggregation was little affected by indome ... | 1986 | 2870502 |
| [therapy of chronic heart failure with vasodilators]. | the chronic heart insufficiency is essentially characterized by a disturbed regulative function of the peripheral circulation. these processes taking place within efforts for compensation close the chain of the vicious circle. the vasodilators with their different principles of effect affect in various places of the vegetative nervous system up to the smooth musculature of the vessels and modulate the peripheral part of the cardiovascular system. via a changed behaviour of the impedance also wit ... | 2006 | 2870591 |
| [therapy of chronic heart failure with vasodilators]. | the chronic heart insufficiency is essentially characterized by a disturbed regulative function of the peripheral circulation. these processes taking place within efforts for compensation close the chain of the vicious circle. the vasodilators with their different principles of effect affect in various places of the vegetative nervous system up to the smooth musculature of the vessels and modulate the peripheral part of the cardiovascular system. via a changed behaviour of the impedance also wit ... | 2006 | 2870591 |
| retention of a functional resact receptor in isolated sperm plasma membranes. | resact, a peptide obtained from eggs, causes a change in the mr, and a loss of 32p from a plasma membrane protein identified as guanylate cyclase. here, a resact analog (125i-[tyr1, ser8] resact) was synthesized and shown to bind to isolated sperm membranes. resact, but not speract, competed with the radiolabeled ligand for binding. when membranes were prepared under appropriate conditions, guanylate cyclase remained at mr 160,000; the incubation of membranes with gamma-32p-atp resulted in the f ... | 2007 | 2870813 |
| retention of a functional resact receptor in isolated sperm plasma membranes. | resact, a peptide obtained from eggs, causes a change in the mr, and a loss of 32p from a plasma membrane protein identified as guanylate cyclase. here, a resact analog (125i-[tyr1, ser8] resact) was synthesized and shown to bind to isolated sperm membranes. resact, but not speract, competed with the radiolabeled ligand for binding. when membranes were prepared under appropriate conditions, guanylate cyclase remained at mr 160,000; the incubation of membranes with gamma-32p-atp resulted in the f ... | 2007 | 2870813 |
| blood-finding strategy of a capillary-feeding sandfly, lutzomyia longipalpis. | salivary gland homogenates of adult female lutzomyia longipalpis inhibited platelet aggregation induced by adp and collagen. apyrase (atp diphosphohydrolase) activity was prominent, requiring ca2+ but not mg2+ and a ph optimum of 8.0. human as well as rabbit hosts developed a well delimited erythema, evident 2-3 min after initial probing and lasting for as long as 2 days. erythema, not accompanied by itching or swelling, developed in previously exposed hosts as well as in those not previously ex ... | 1986 | 2870860 |
| blood-finding strategy of a capillary-feeding sandfly, lutzomyia longipalpis. | salivary gland homogenates of adult female lutzomyia longipalpis inhibited platelet aggregation induced by adp and collagen. apyrase (atp diphosphohydrolase) activity was prominent, requiring ca2+ but not mg2+ and a ph optimum of 8.0. human as well as rabbit hosts developed a well delimited erythema, evident 2-3 min after initial probing and lasting for as long as 2 days. erythema, not accompanied by itching or swelling, developed in previously exposed hosts as well as in those not previously ex ... | 1986 | 2870860 |
| the electrocardiogram of european shrews. | a recording method of electrocardiograms in resting animals is described. the electrocardiograms of crocidura russula, crocidura leucodon, crocidura suaveolens, neomys fodiens and sorex araneus are similar to those of other small mammals. t-wave directly follows the qrs-complex. the duration of electrocardiograms depends on heart mass and body temperature. heart rate shows no influence on the duration of electrocardiograms. | 2007 | 2870871 |
| the electrocardiogram of european shrews. | a recording method of electrocardiograms in resting animals is described. the electrocardiograms of crocidura russula, crocidura leucodon, crocidura suaveolens, neomys fodiens and sorex araneus are similar to those of other small mammals. t-wave directly follows the qrs-complex. the duration of electrocardiograms depends on heart mass and body temperature. heart rate shows no influence on the duration of electrocardiograms. | 2007 | 2870871 |
| pharmacokinetics of t-2 toxin and its metabolite ht-2 toxin, after intravenous administration in dogs. | the pharmacokinetics of t-2 toxin and ht-2 toxin were investigated comparatively in five dogs, after iv administration of the toxins (0.4 mg/kg). t-2 toxin was very rapidly and almost completely biotransformed to ht-2 toxin (fm = 83.6 +/- 3.9%). the following mean pharmacokinetic parameters were determined in this study for t-2 toxin and ht-2 toxin, respectively: half-life 5.3 +/- 2.1 and 19.6 +/- 4.7 min, clearance 0.107 +/- 0.056 and 0.167 +/- 0.074 liters/min/kg, and volume of distribution 0. ... | 1986 | 2870902 |
| pharmacokinetics of t-2 toxin and its metabolite ht-2 toxin, after intravenous administration in dogs. | the pharmacokinetics of t-2 toxin and ht-2 toxin were investigated comparatively in five dogs, after iv administration of the toxins (0.4 mg/kg). t-2 toxin was very rapidly and almost completely biotransformed to ht-2 toxin (fm = 83.6 +/- 3.9%). the following mean pharmacokinetic parameters were determined in this study for t-2 toxin and ht-2 toxin, respectively: half-life 5.3 +/- 2.1 and 19.6 +/- 4.7 min, clearance 0.107 +/- 0.056 and 0.167 +/- 0.074 liters/min/kg, and volume of distribution 0. ... | 1986 | 2870902 |
| anxiolytic effects of progesterone are sexually dimorphic. | we evaluated the effects of progesterone administration to estrogen-primed rats on licking behavior during a lick suppression test. this test assesses the behavior of water-deprived rats to lick a drinking tube for water reinforcement that is paired to electric shock. chlordiazepoxide (a commonly used tranquilizer) is very effective in increasing licking during this test. normal females and neonatally castrated males displayed an increase in shock-punished responses in tests conducted after horm ... | 1986 | 2871472 |
| chronic treatment with iprindole reduces immobility of rats in the behavioural 'despair' test by activating dopaminergic mechanisms in the brain. | iprindole, 10 mg kg-1 i.p., once daily for 21 days, enhanced the metabolism of dopamine in the frontal cortex and striatum of rats with no effect in the nucleus accumbens 1 h after the last injection. noradrenaline metabolism in the brainstem and telencephalon was also increased in these conditions. no effect on dopamine or noradrenaline metabolism was seen 24 h after the last injection. the same repeated treatment schedule with iprindole markedly reduced the immobility of rats in the behavioura ... | 1986 | 2872301 |
| 5-(2-cyclohexylideneethyl)-5-ethyl barbituric acid (cheb): correlation of hypnotic and convulsant properties with alterations of synaptosomal 45ca2+ influx. | male icr mice (20-35 g) were given either 5-(2-cyclohexylideneethyl)-5-ethyl barbituric acid (cheb) alone (10-15 mg/kg i.p.) or cheb (25-75 mg/kg i.p.) after a 1 h pretreatment with phenobarbital (75 mg/kg i.p.). cheb alone (10 mg/kg) produced excitatory behavior but not convulsive seizures. higher doses (11-15 mg/kg) produced convulsive seizures resulting in death. pretreatment with phenobarbital prevented seizure activity. following phenobarbital pretreatment, cheb in doses of 50 and 75, but n ... | 1986 | 2875881 |
| the ir-thy-1 concept: continuing saga. | 2010 | 2876044 | |
| stimulant action of ethanol on posttetanic potentiation of hindlimb monosynaptic reflexes. | 1986 | 2876435 | |
| [hismanal--a new nonsoporific hay fever medication]. | 2010 | 2876531 | |
| non-haemagglutinating fimbriae of enteropathogenic escherichia coli (epec). | two hundred and thirteen escherichia coli strains originating in 12 countries were included in the study. of these, 157 were classical enteropathogenic e. coli (epec) serotypes, 54 belonged to o138, o139 and o141 serogroups i.e. porcine edema disease strains and two strains were of serogroup o157 associated with haemorrhagic colitis. surface hydrophobicity was determined by the salt aggregation test (sat). haemagglutination was assayed against erythrocytes of six animal species with strains grow ... | 1986 | 2876564 |
| an n-methyl-d-aspartate (nmda) receptor antagonist reduces bicuculline-induced depolarization shifts in neocortical explant cultures. | we investigated the actions of a specific n-methyl-d-aspartate (nmda) antagonist, 2-amino-5-phosphonovaleric acid (2-apv), on bicuculline-induced epileptogenesis in organotypic explant cultures from neonatal rat neocortex. explants were maintained in roller tubes for 3-5 weeks. the late, plateau phase of the intracellularly recorded paroxysmal depolarization shift was sensitive to both intracellularly injected hyperpolarizing currents and 2-apv, suggesting that this component is generated by a v ... | 1986 | 2877418 |
| media for isolating shigella. | 1987 | 2881104 | |
| comparison of the effects of fe2+ and cu2+ on prostaglandin synthesis in rabbit kidney medulla slices. | the effects of fe2+ and cu2+ on the generation of medullary prostaglandins e2 and f2 alpha have been compared. fe2+ markedly promoted the lipid peroxidation of rabbit kidney medulla slices. the lipid peroxidation induced by fe2+ inhibited both prostaglandin e2 and prostaglandin f2 alpha formation to a similar extent. while cu2+ produced only a small increase in lipid peroxidation, it had a powerful inhibitory effect on prostaglandin e2 formation. simultaneously, prostaglandin f2 alpha production ... | 1987 | 2883291 |
| first-trimester prenatal diagnosis for huntington's disease with dna probes. | polymorphic dna probes linked to the locus for huntington disease (hd) were used for prenatal diagnosis of a 10-week fetus at 25% risk for the disease. the fetus proved to have a 48% risk of having inherited the hd mutation which was similar to that for the at-risk parent (50%). on this basis the parents elected to terminate the pregnancy. when appropriate family members are available and dna studies are informative, prenatal diagnosis of hd with polymorphic dna probes can determine the at-risk ... | 2010 | 2884412 |
| exposure to benzodiazepines in utero. | 2010 | 2884529 | |
| plasmid-mediated resistance to nalidixic acid in shigella dysenteriae type 1. | in an epidemic of shigellosis in southern bangladesh the causal organism, shigella dysenteriae type 1, was resistant to nalidixic acid as well as to co-trimoxazole (trimethoprimsulphamethoxazole) and ampicillin. the genes coding for resistance to nalidixic acid, but not those coding for resistance to co-trimoxazole or ampicillin, are located on a conjugative 20 megadalton plasmid. this epidemic is of particular importance because of the resistance to nalidixic acid, an antibiotic to which shigel ... | 1987 | 2887725 |
| congenital adrenal hyperplasia. | 2010 | 2887945 | |
| bioactivity and immunoreactivity of tumour necrosis factor in cancer patients. | 2010 | 2893076 | |
| why does placebo improve severe limb ischaemia? | 2010 | 2893161 | |
| enhancement of contractile responses to partial alpha-adrenoceptor agonists during warming in rat aorta. | we examined the effects of warming on the contractile responses to full and partial alpha-adrenoceptor agonists in rat aorta. the contractions elicited by norepinephrine and methoxamine were not affected during warming (40 degrees c, 42 degrees c), whereas those induced by clonidine and st 587 were significantly enhanced. kcl-induced contractions of rat aorta were not affected by warming. the dissociation constants of clonidine and st 587 at 40 degrees c were not different from those at 37 degre ... | 1987 | 2895427 |
| clinical impact of drug resistance. | 1988 | 2896697 | |
| hay fever treatments--which should be tried first? | a series of comparative trials on nine popular and pharmacologically distinct regimens for the treatment of hay fever was undertaken in the course of normal general practice in the pollen seasons of 1981-83. one hundred and forty doctors recruited 640 patients to assess the overall usefulness of the treatments on daily diaries. ;usefulness' was scored on a linear analogue scale weighing up the degree of hay fever symptoms during treatment, side effects and ease of use of the preparation.the regi ... | 2010 | 2896796 |
| [endodontic approach to injured teeth]. | 2010 | 2897345 | |
| a selective inhibitor of camp-specific phosphodiesterase, ro 20-1724, has no effect on the quantal release of acetylcholine from the mouse phrenic nerve. | the indirect twitch response of the mouse isolated phrenic nerve-diaphragm preparation, partially paralysed by tubocurarine, was restored only by about 10% by ro 20-1724 at 2 to 280 microm. the solvent vehicle, dimethylsulphoxide, also showed the same effect to a similar extent. intracellular recordings with glass microelectrodes revealed that ro 20-1724 (40 microm) affected neither the resting membrane potential, the amplitude and frequency of miniature endplate potentials nor the amplitude of ... | 1988 | 2897454 |
| dysentery due to multiresistant shiga bacillus in rural iran. | 1988 | 2902359 | |
| nalidixic-acid resistant shigella dysenteriae type 1 in eastern india. | 1988 | 2902361 | |
| molecular neurobiology--a conference sponsored by the nimh. | 2010 | 2902686 | |
| brain cellular injury and recovery--horizons for improving medical therapies in stroke and trauma. | an edited summary of an interdepartmental conference arranged by the department of medicine of the ucla school of medicine, los angeles. the director of conferences is william m. pardridge, md, professor of medicine. after ischemic and traumatic brain injury, many cells may be rendered dysfunctional but are not irreversibly damaged or disrupted. the brain tissue may become metabolically deranged, and neurons, while still alive, are paralyzed and cannot create an action potential or conduct an el ... | 1988 | 2902711 |
| [the expression of c-myb is strongly associated with the presence of estrogen and progesterone receptors in breast cancer]. | the c-myb gene was studied in 112 breast cancers. c-myb and estrogen receptor (er) transcripts were found in 78 (70%) and 71 (63%) cancers respectively. of these 71 er positive cancers, 64 (90%) contained c-myb transcripts and of the 41 er negative cancers, 27 (66%) did not contain c-myb mrna. our data show that c-myb transcripts are strongly associated with er and progesterone receptors (p less than 10(-4) status in breast cancer. thus the c-myb expression could be associated with breast cancer ... | 2010 | 2907731 |
| improved sexual function in hemodialysis patients on recombinant erythropoietin: a possible role for prolactin. | as it was reported that correction of anemia in long-term hemodialysis patients by recombinant human erythropoietin (r-huepo) is associated with improved sexual function, we conducted the present study to further delineate the mechanism(s) by which this is brought about. serum prolactin, testosterone, and parathyroid hormone (pth) levels were followed during 4 months of r-huepo therapy. within 4 months of treatment with r-huepo, hematocrit values rose from 23.7 +/- 1.2 to 35.7 +/- 0.2% and hemog ... | 1989 | 2914405 |
| arthrodesis of metatarsophalangeal joints in a dog. | chronic osteomyelitis and septic arthritis involving the 3rd and 4th metatarsophalangeal joints were diagnosed in a doberman pinscher. arthrodesis of the 3rd and 4th metatarsophalangeal joints resulted in a subtle persistent gait abnormality, but limb function was preserved. arthrodesis of metatarsophalangeal joints is an alternative to amputation, especially when main weight-bearing digits are involved. | 1989 | 2914800 |
| uptake of 63ni2+ in the central and peripheral nervous system of mice after oral administration: effects of treatments with halogenated 8-hydroxyquinolines. | oral administration of 63ni2+ to mice resulted in higher levels of the metal in the sciatic nerves, the trigeminal ganglia, spinal nerve roots and the spinal cord than in the cerebellum and the frontal cortex. in the sciatic nerves, the trigeminal ganglia and the spinal nerve roots a high vascular permeability may explain the preferential uptake of the 63ni2+. the higher accumulation of the 63ni2+ in the spinal cord than in the examined structures of the brain may be related to a diffusion from ... | 2010 | 2916242 |
| [screening of cancer, advantages and disadvantages]. | 2010 | 2916263 | |
| the protective effect of thromboxane synthetase inhibition on renal function in systemic sepsis. | to study the role of thromboxane in systemic sepsis and renal failure, peritonitis was induced surgically in 22 sheep, leading to local and systemic sepsis. a selective thromboxane synthetase inhibitor, u63,557a (upjohn co, kalamazoo, mi) was given before surgery in five animals and 30 minutes after surgery in five animals. a typical picture of volume-loaded, normotensive, vasodilated septic shock developed in all animals. twenty four hours after induction of sepsis, the control group showed a m ... | 1989 | 2916566 |
| arrhythmia or artifact? | 2010 | 2916599 | |
| focus on scotland. taking the high road. interview by sue smith. | 2010 | 2920555 | |
| sensitivity of campylobacter pylori to colloidal bismuth subcitrate. | 1989 | 2921366 | |
| [the administration of calcium channel blockers in patients with cerebrovascular diseases]. | 2010 | 2922083 | |
| [the treatment of severe, therapy-resistant depression using infusions of antidepressants]. | infusion-therapy with antidepressants has been of value in severe as well as therapy resistant depressive states. in addition to doses lower than those used for oral treatment, a more rapid onset of therapeutic effect and a better tolerance, the beneficial effect seems also to depend on the setting in which the treatment takes place. infusion-therapy is a combined pharmacopsychotherapeutic procedure. next to infusion-treatment a pretreatment with neuroleptics is advised either via the oral or pa ... | 2010 | 2922514 |
| anal duct carcinoma. | 2010 | 2924675 | |
| functional significance of the kunitz-type inhibitory domains of lipoprotein-associated coagulation inhibitor. | blood coagulation can be initiated when factor vii or viia, a plasma protease, binds to its essential cofactor, tissue factor (tf), and proteolytically activates factors ix and x, triggering a cascade of events which eventually leads to the formation of thrombin and a fibrin clot. plasma contains a lipoprotein-associated coagulation inhibitor (laci) which inhibits activated factor x (xa) directly and, in a xa-dependent way, inhibits vii(a)/tf activity, presumably by forming a quaternary xa/laci/ ... | 2010 | 2927510 |
| three potassium currents in mouse motor nerve terminals. | a study of the k conductance of the presynaptic membrane has been performed in the triangularis sterni muscle of the mouse. external currents generated in the presynaptic terminals upon invasion by action potentials have been recorded using microelectrodes inserted into the perineurium of preterminal nerve bundles. the voltage-dependent k current could be pharmacologically dissected into fast (ikf) and slow (iks) components. while both are sensitive to 3,4-diaminopyridine (3,4-dap), only ikf is ... | 1989 | 2928092 |
| nontraditional pedagogy for implementing human genetics education. | 1989 | 2929601 | |
| ptsd and suicide attempts by adolescents. | 2010 | 2929769 | |
| adp-ribosylatable content of elongation factor-2 changes during cell cycle of normal and cancerous human cells. | the amount of protein elongation factor ef-2 that can be inactivated by diphtheria toxin-mediated adp-ribosylation, a measure of its active content, decreases by 45% and 66% in g1-arrested normal human fibroblasts and in hela cells respectively. on restimulation of cells with fresh serum, the amounts of adp-ribosylatable ef-2 begin to increase within 4 h. whereas the level of active ef-2 returns to normal (exponential phase of growth) in 20 h in the case of fibroblasts, only 47% recovery was obs ... | 1989 | 2930555 |
| [nutrition in the etiology of breast cancer. results of a survey in austria]. | 2010 | 2934651 | |
| [horizontal laparotomy in biliary tract surgery]. | for operations on the biliary tract the transverse horizontal incision has the same advantages as the subcostal approach: strong abdominal wall, little influence on ventilation and wide access to the subhepatic region. but in addition, the abdominal wall nerves are preserved as much as possible, post-operative evisceration, it is occurs, can easily be repaired and subsequent surgery can be performed using the same route. | 2010 | 2934697 |
| [hormonal status of girls in the neutral, prepubertal and pubertal periods of life]. | 2010 | 2935044 | |
| solvent interactions with n, n-dialkylnicotinamides and their effects on rotational barriers. | carbon-13 nuclear magnetic resonance techniques were employed to examine the effects of solvent environment on rotational barriers in a series of molecules structurally-related to the analeptic, nikethamide: n,n-dimethylnicotinamide, n,n-di-n-propylnicotinamide, and 1-nicotinoyl piperidine. total bandshape analysis was performed for the exchanging alkyl carbon resonances of these compounds as a function of temperature in four solvent systems: d2o, ch3od, ch3ch2od and cdcl3. the rate constants fo ... | 2010 | 2937406 |
| outcome of early surgery after coronary angioplasty. | nineteen of 69 patients undergoing coronary angioplasty required immediate coronary surgery after the procedure. six of these operations were planned as a result of angioplasty that failed without producing any complication. the remaining 13 cases were operated upon because complications occurred during angioplasty. these were coronary artery dissection in four, occlusion in five, continuing severe spasm in two, tamponade in one, and in one other detachment of a guidewire tip. in these 13 cases ... | 2010 | 2937432 |
| the incidence of cardiac arrhythmias during intravenous digital subtraction angiography: a comparison of peripheral and central injections. | intravenous digital subtraction arteriography (iv-dsa) was carried out in 204 patients with arteriosclerotic peripheral vascular disease using the non-ionic contrast medium iopamidol 370. in 124 patients the injection was made into an antecubital vein and in 80 into the right atrium. rhythm strip electrocardiograms showed no significant difference in incidence or type of arrhythmias between either injection method (p greater than 0.95). | 2010 | 2941437 |
| dose-related effects of synthetic human beta-endorphin and naloxone on fed gastrointestinal motility. | in humans, plasma beta-endorphin levels rise during application of acute stressful stimuli (vertigo, cold pain, and transcutaneous electrical stimulation) that induce gut motor disturbances. whereas it is possible that circulating beta-endorphin participates in the mediation of these central effects on gut motility, its role cannot be established solely on the basis of changes in plasma levels. therefore, we designed the present study to investigate 1) the dose-related effects of intravenous syn ... | 1986 | 2942039 |
| abnormal systolic time intervals in obesity and their relationship with the amount of overweight. | we studied 17 severely obese subjects (age range 26 to 42 years), without hypertension, diabetes mellitus, angina, or clinical signs of heart failure or respiratory disease, and 16 age-matched control subjects. x-teleroentgenographic findings (transverse cardiac diameter and cardiothoracic ratio), blood pressure, and mechanocardiographic parameters were analyzed in both groups. by means of conventional simultaneous recordings of ecg, phonocardiogram, and carotid pulse (100 mm/sec), systolic time ... | 2010 | 2943149 |
| utilization of formal social support services by non-institutionalized ill elderly. | 2009 | 2948279 | |
| [clinical survey on adverse reactions of contrast media (2d report)]. | 2010 | 2950377 | |
| validity of an operational definition for neurotic unipolar major depression. | after we reviewed the literature to identify the clinical and phenomenologic correlates of neurotic depression, we constructed a 6-item operational definition to distinguish neurotic unipolar major depressive disorder from non-neurotic major depression. the neurotic depressives were characterized by a low rate of abnormal dexamethasone suppression test (dst) results and a strong family history of alcoholism. neurotic depressives improved less than non-neurotic depressives during the index hospit ... | 2010 | 2952692 |
| comparison of atracurium and d-tubocurarine for prevention of succinylcholine myalgia. | we compared the incidence of postoperative myalgia (pom) and fasciculations when atracurium (atr) or d-tubocurarine (dtc) was given prior to succinylcholine (sdc) for tracheal intubation in 44 asa class i or ii outpatient females undergoing laparoscopy. the subjects were assigned to one of three groups: group 1 received 0.025 mg/kg atr; group 2 received 0.05 mg/kg dtc; and group 3 received saline (ns), all in a double-blind manner. thiopental was administered 1 min and 45 sec after pretreatment ... | 2010 | 2955717 |
| effect of b cell stimulatory factor-1 (interleukin 4) on fc epsilon and fc gamma receptor expression on murine b lymphocytes and b cell lines. | culture of murine splenic b cells with interleukin 4 (il-4) caused the up-regulation of the lymphocyte fc receptor for immunoglobulin e (ige) (fc epsilon r) over a similar dose range as required for ia up-regulation. however, the expression level of the fc receptor for immunoglobulin g (fc gamma r) did not increase, rather il-4 caused a slight but consistent decrease in the fc gamma r level on the b cells. fc epsilon r+ b hybridoma cells also responded to il-4 by exhibiting increased fc epsilon ... | 1987 | 2958544 |
| an outbreak of dysentery due to shigella dysenteriae type 1 in rangoon, burma. | 1987 | 2963061 | |
| lowering effect of pantethine on plasma beta-thromboglobulin and lipids in diabetes mellitus. | pantethine in a dosage of 600 mg for the first 3 months, and in a dosage of 1200 mg for the second 6 months was given to 16 diabetics in whom plasma beta-thromboglobulin was raised (greater than 50 ng/ml). plasma beta-tg levels decreased significantly with pantethine treatment for 9 months. plasma triglyceride, total cholesterol, apo e and apo cii levels decreased significantly after 9 months. plasma ldl-c and atherogenic index (ldl-c/hdl-c ratio or apo b/apo ai ratio) tended to decrease with tr ... | 2010 | 2963604 |
| [effect of nicotinic acid, nicotinamide and its combination with ziksorin and phenobarbital on the udp glucuronyl transferase activity of the hepatic endoplasmic reticulum in the rat]. | nicotinic acid and nicotinamide (100 mg/kg) increase the activity of the rat liver microsomal uridine diphosphate-glucuronyltransferase by 55 and 73.8%. administration of nicotinamide in combination with ziksorin or phenobarbital enhanced the enzyme-inducing effects of the latter. | 1988 | 2966073 |
| [193 cases of gastroschisis and omphalocele--postoperative results]. | treatment was applied to 97 cases of omphalocele and 96 cases of gastroschisis at the dortmund department of paediatric surgery over the past 20 years. the survival rate was 122. follow-up checks were recently applied to 56 of those former patients, after nearly ten years had elapsed from surgery. thirty-eight of these patients were clinically examined, while questionnaires were completed for the rest. primary closures had been performed on 50 per cent of the cases, while the defects in the othe ... | 2010 | 2966527 |
| epidemiological aspects of plasmid profiles in shigella dysenteriae type 1 strains isolated from burma & india. | 1987 | 2967798 | |
| the "phantom" optic nerve. demonstration in ct and mr scans 19 years after resection of optic glioma. | 2003 | 2972753 | |
| neuroendocrine effects of diazepam in normal subjects following brief painful stress. | the neuroendocrine effects of 5 and 10 mg of oral diazepam were assessed in 10 normal subjects under baseline (prestress) and laboratory-controlled stressful conditions. although the 10-mg diazepam dose had no effect on cortisol at baseline, it significantly reduced the increase in cortisol produced by 15 minutes of exposure to a painful electrical stimulus. there were no significant effects on growth hormone, beta-endorphin or acth, either at baseline or after painful stimulation. | 2003 | 2972756 |
| [pathological aging of the brain. personal observations on the use of citicoline]. | 2010 | 2973933 | |
| [fibrinolytic therapy of thromboembolic vascular occlusions: experiences based on 87 patients]. | 2010 | 2974192 | |
| [current approaches to immunological diagnosis of autoimmune and immune complex diseases]. | 2010 | 2974642 | |
| [prevention of the problems of alcoholism]. | 2010 | 2975175 | |
| the relationships between oligomeric structure and function of band 3 protein from human erythrocyte membranes: present knowledge and suggestions for further experiments. | 1988 | 2976450 | |
| principles of the diagnostic system 'orfèvre' for computerized analysis in radiology. | 2010 | 2980470 | |
| plasma atrial natriuretic peptide concentrations during induction of anesthesia and acute volume loading in patients undergoing cardiac surgery. | induction of anesthesia with fentanyl for coronary artery bypass grafting decreased (p less than .05) plasma atrial natriuretic peptide (anp) concentrations from awake values in twelve patients. during a steady state of anesthesia before surgery, isotonic saline solution (10 ml/kg) was infused simultaneously with the elevation of the lower extremities in six patients, while six subjects served as controls receiving no volume loading and having no leg raising. the anp levels returned to the awake ... | 2010 | 2980951 |
| middle tumor antigen of polyomavirus transformation-defective mutant ng59 is associated with pp60c-src. | we have found that lysis of mouse embryo cells infected with the polyomavirus host range transformation-defective (hr-t) mutant ng59 under gentle conditions that avoid ionic detergents results in detectable ng59-encoded middle tumor antigen (mtag) associated with pp60c-src. this mtag-pp60c-src complex could be immunoprecipitated from ng59-infected cell lysates by either sera from animals bearing polyomavirus-induced tumors or by monoclonal antibodies directed against mtag. immune complex kinase ... | 1985 | 2981329 |
| serologic survey of rotavirus, norwalk agent and prototheca wickerhamii in wastewater workers. | analysis of paired sera from 48 wastewater workers and controls who reported gastrointestinal illness did not reveal any excess of seroconversions to norwalk agent or to rotavirus. inexperienced wastewater-exposed workers had higher levels of antibody to norwalk agent than did experienced and control workers and those with high and medium aerosol exposure had higher titres than those in the low aerosol category. analysis for prototheca antibody titres was essentially negative. | 1985 | 2981485 |
| immunologic characterization of herpes simplex virus type 2 antigens icp10 and icsp11/12. | infected cell protein 10 (icp10) or antigen 4 (ag4) and infected cell-specific protein 11/12 (icsp11/12) have been suggested as specific antigenic markers for cervical carcinoma. experiments were designed to determine whether icp10 and icsp11/12 are distinct antigens and to determine the cellular localization of icp10. results indicate that an apparent 160 kdalton (kda) protein analyzed by 8.5% polyacrylamide gels (= 144 kda protein analyzed by 7.0% polyacrylamide gels) was detected in hsv-2-inf ... | 1985 | 2988230 |
| induction of cellular dna synthesis by a simian virus 40 mutant defective in nuclear transport of t antigen. | the simian virus 40 (sv40) (ct)-3 mutant [sv40(ct)-3], which is defective in nuclear transport of t antigen, was utilized to determine whether cellular dna synthesis can be stimulated by sv40 in the absence of detectable nuclear t antigen. cellular dna synthesis was examined in the temperature-sensitive cell cycle mutants, bhk ts13 and bhk tsaf8, after microinjection of quiescent cells with plasmid dna containing cloned copies of wild-type sv40 or sv40(ct)-3. the efficiency of induction of cellu ... | 1985 | 2993869 |