Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| cloning and expression of the gene(s) for cephalosporinase production of citrobacter freundii. | the chromosomal gene(s) for cephalosporinase production of citrobacter freundii gn346 has been cloned into vector plasmid pmk1, initially as a 7.3 kb ecori fragment. from the substrate profile and the response to anti-gn346 csase serum of the enzyme produced, it was confirmed that the hybrid plasmid (pty71) carries the relevant chromosomal cephalosporinase gene from c. freundii gn346. a restriction endonuclease cleavage map of cloned ecori fragments was constructed, and the structural gene of th ... | 1983 | 6304475 |
| in vitro activity and beta-lactamase stability of cefodizime, an aminothiazolyl iminomethoxy cephalosporin. | cefodizime, an iminomethoxy aminothiazolyl cephalosporin similar to moxalactam and ceftazidime, was less active (minimal inhibitory concentration, 1.6 to 12 micrograms) than cefazolin or cefotaxime against staphylococcus aureus and staphylococcus epidermidis. it inhibited haemophilus and neisseria spp. at less than 0.5 microgram/ml. it did not inhibit methicillin-resistant staphylococci, enterococci, or listeria spp. and was 8- to 32-fold less active than cefotaxime, moxalactam, or ceftazidime a ... | 1983 | 6311090 |
| [in vitro antibacterial activity of cefmenoxime (sce 1365)]. | 617 clinical isolates were tested, 592 of which were from hospital source. the minimal inhibitory concentrations of cefmenoxime were determined by a microtiter dilution method, using mueller-hinton broth. the results obtained give a 92% agreement with the reference agar-dilution method. cefmenoxime shows a potent activity against enterobacteriaceae (n = 420): the modal mic is less than or equal to 0,03 mg/l, and 90% of them are inhibited by 1 mg/l. some isolates require a higher concentration, a ... | 1983 | 6312394 |
| [in vitro bacteriostatic activity of cefmenoxime (sce 1365), cefotaxime and moxalactam]. | the in vitro activity of cefmenoxime (sce 1365), a new cephalosporin derivate was compared with two other "third generation" cephalosporins: cefotaxime and moxalactam. cefmenoxime as cefotaxime and moxalactam were very active against 305 cephalosporinase-producing and cephalosporinase-non-producing enterobacteriaceae. cefmenoxime was the most active against serratia marcescens, citrobacter freundii, morganella morganii, salmonella, shigella and yersinia enterocolitica with a mean mic at least tw ... | 1983 | 6312395 |
| kinetic studies on inactivation of citrobacter freundii cephalosporinase by sulbactam. | the inactivation kinetics for inhibition by sulbactam (cp45,899) of citrobacter freundii gn346 cephalosporinase were studied in detail and compared with those of type ib penicillinase or tem-2 beta-lactamase mediated by r plasmid rgn823. the rate constant for progressive inactivation of the cephalosporinase was significantly larger than that measured with the penicillinase. the number of sulbactam molecules required to cause complete inactivation of one cephalosporinase molecule (turnover number ... | 1983 | 6312873 |
| [distribution of specific endodeoxyribonucleases in different strains of citrobacter freundii]. | 1983 | 6313311 | |
| in vitro activity of hr 810, a new broad-spectrum cephalosporin. | hr 810, 3-[(2,3-cyclopenteno-1-pyridinium)methyl]-7-[2-syn-methoximino-2-(2-aminothiazole-4-yl)-acetamido] ceph-3-em-4-carboxylate, is a new semisynthetic cephalosporin derivative. the in vitro activity of hr 810 was compared with that of cefotaxime, ceftazidime, piperacillin and gentamicin using 368 strains of gram-negative and gram-positive bacteria. hr 810 was highly active against enterobacteriaceae, being the most active of the cephalosporins against enterobacter, serratia and citrobacter s ... | 1983 | 6313358 |
| [comparison of sensitivity patterns of bacteria isolated from clinical materials to the 2d generation cephamycins and cephalosporins and clinical application of these antibiotics]. | in vitro susceptibilities of 1478 strains of various pathogens isolated from clinical materials in 1981 to 23 antibiotics were studied using showa disk diffusion test. prevalence of bacterial resistance to antibiotics was evaluated. new cephem antibiotics such as cefmetazole (cmz), cefoxitin (cfx) and cefotiam (ctm) had no increased activity over old cephalosporins such as cephalothin (cet) and cefazolin (cez) against gram-positive cocci. however, all the new ones showed greater activities, broa ... | 1983 | 6317908 |
| survey, purification, and properties of sugar phosphate phosphohydrolase among microorganisms. | sugar phosphate phosphohydrolase was purified approximately 500- to 600-fold to apparent homogeneity from escherichia coli b, escherichia coli c, escherichia coli var. communior, escherichia acidilactici, enterobacter aerogenes, neisseria meningitidis, and saccharomyces cereviseae. the molecular weights of the enzyme as estimated by gel filtration ranged from 97 x 10(3) to 101 x 10(3). the enzyme was composed of two subunits with the same molecular weight which ranged from 50 x 10(3) to 52 x 10( ... | 1983 | 6322944 |
| [specificity of new restrictases and methylases. unusual modification of cytosine at position 4]. | fourteen restriction endonucleases and 4 methylases were isolated and purified from 14 strains of citrobacter freundii and escherichia coli, which were isolated from natural sources. to determine the nucleotide sequence recognized by the endonucleases a comparison of dna cleavage patterns, the evaluation of the cleavage frequency of some dna with known recognition sequences and mapping was used. it was determined that cfr101 is a new enzyme recognizing 5'puccggpy. other restriction enzymes isola ... | 1984 | 6323968 |
| [sensitivity of the recent bacterial isolates to cefotaxime and other cephem antibiotics]. | antimicrobial susceptibility of 703 nonselected strains of 14 different bacterial species to cefazolin, cefmetazole, cefotiam, cefoperazone latamoxef, and cefotaxime (ctx) was examined. ctx was the most active against e. coli, klebsiella, serratia, p. mirabilis, h. influenzae, beta-streptococcus group a, beta-streptococcus group b and s. pneumoniae. on the other hand, ctx-resistant (mic greater than or equal to 50 micrograms/ml) strains were isolated at the following frequencies: citrobacter, 21 ... | 1983 | 6325747 |
| [spectrum of resistance of various bacteria against cefotiam in 3 berlin clinics]. | the in vitro activity of cefotiam ( spizef ) was tested using the agar diffusion test method according to din 58940 and compared with the antibacterial activity of 12 other routinely tested antibacterial chemotherapeutics. a total of 3000 strains from patients' specimens from the university hospital of the free university of berlin and the municipal wenckebach hospital, west berlin, was tested. cefotiam proved effective against strains of staphylococcus aureus in 99,4%, escherichia coli in 99,7% ... | 1983 | 6327506 |
| pivmecillinam for bacteriuria in pregnancy. | pivmecillinam was given to 44 women with bacteriuria in pregnancy. treatment was successful in 33 (87%) out of the 38 patients assessed. thirty women subsequently received at random either a low-dose of pivmecillinam for up to three months or acted as a control group. further bacteriuric episodes during pregnancy were recorded only in three patients in the control group. thirty-nine out of the 41 women followed to term delivered healthy babies. one infant was stillborn and another child had a cl ... | 1984 | 6327600 |
| [in vitro activity of ceftizoxime on hospital bacteria. results of a multicenter study]. | the susceptibility to ceftizoxime of all bacterial strains isolated from seven university-affiliated hospitals over one month was tested with disk-diffusion technique. additionally, the mic of 1937 strains selected at random was evaluated by the agar dilution method. the majority of enterobacteriaceae are inhibited at a concentration of less than 1 microgram/ml with a mode mic varying from 0.008 to 0.12 among the various groups. a few enterobacter and citrobacter strains are resistant. little ac ... | 1984 | 6330645 |
| [resistance of enterobacteria to cefotaxime and lamoxactam at the pitié-salpêtrière hospital in 1982]. | systematic collection of data on every enterobacteriaceae clinical isolate cultured in the central bacteriology laboratory allowed comparison of the percentage of cefotaxim (ctx) and moxalactam ( mox ) intermediate or resistant (ir) strains among the 8 199 enterobacteriaceae isolated in 1982 and the 5 032 enterobacteriaceae isolated in 1980. in 1982, ir rates were 2% to ctx and 0.6% to mox . among the 166 strains ir to ctx, 28% were also ir to mox . two strains only were ir to mox but not to ctx ... | 1984 | 6330650 |
| bacterial changes in the urine samples of patients with long-term indwelling catheters. | the bacterial flora in the urine samples of 15 nursing home patients with long-term, indwelling catheters were examined monthly for one year. there was a rapidly changing polymicrobial flora averaging 2.0 changes per month in species with colony counts greater than 100,000/ml, and 3.2 changes per month when changes in species, biogram, and quantity of bacteria were considered. the flora changed significantly more frequently, and cultures of pseudomonas aeruginosa, providencia stuartii, and citro ... | 1984 | 6331806 |
| comparative in vitro activity and beta-lactamase stability of fr 17027, a new orally active cephalosporin. | fr 17027, a new orally absorbed cephalosporin ester, inhibited group a and b streptococci and streptococcus pneumoniae at less than or equal to 0.1 micrograms/ml, which is similar to the inhibition concentration of amoxicillin and cefaclor, and was more active than cephalexin. it was less active (mic, 25 micrograms/ml) against staphylococci than was cephalexin, and it did not inhibit streptococcus faecalis or listeria monocytogenes. fr 17027 inhibited beta-lactamase-producing isolates of neisser ... | 1984 | 6333207 |
| synergism of ps-5 with penicillins and cephalosporins in antimicrobial activity against beta-lactam-resistant gram-negative microorganisms. | the in vitro synergism of ps-5 combined with various penicillins and cephalosporins in antimicrobial activity was examined in detail against beta-lactam-resistant gram-negative bacteria. ps-5 showed a highly significant synergism in antimicrobial action against escherichia coli rgn238 in combination with penicillins; and against proteus vulgaris gn76 and serratia marcescens t55 in combination with cephalosporins. it was moderately synergistic against citrobacter freundii gn346, enterobacter cloa ... | 1984 | 6334679 |
| selection of resistant mutants of citrobacter freundii by second and third-generation cephalosporins and imipenem. | using a single-step selection procedure, resistant mutants could be obtained from three clinical isolates of citrobacter freundii with two second-generation and four third-generation cephalosporins but not with imipenem. all mutants showed a drastically increased beta-lactamase activity and were cross-resistant to all the cephalosporins examined. combinations of cloxacillin with the cephalosporins were markedly synergistic, suggesting the principal role of the cephalosporinase in the resistance ... | 1984 | 6335134 |
| beta-lactamase production in enterobacter cloacae and citrobacter freundii. | the beta-lactamase activity with ampicillin (a) and cephalothin (ce) as substrate was examined in 28 strains of ent. cloacae and 24 strains of c. freundii by a micro-iodometric-(mia) and an ultraviolet assay (uva). carbenicillin resistance (ca-r) was present in 32 strains (16 of each species). all ca-resistant (ca-r) strains had elevated amounts of beta-lactamase. the conditions were very similar in the two species. the ca-r strains could be divided into two subgroups. one group had very high am ... | 1984 | 6335817 |
| new medium for improved recovery of coliform bacteria from drinking water. | a new membrane filter medium was developed for the improved recovery of injured coliforms from drinking water. the new medium, termed m-t7, consists of 5.0 g of difco proteose peptone no. 3, 20 g of lactose, 3.0 g of yeast extract, 0.4 ml of tergitol 7 (25% solution), 5.0 g of polyoxyethylene ether w-1, 0.1 g of bromthymol blue, 0.1 g of bromcresol purple, and 15 g of agar per liter of distilled water. additional selectivity may be obtained by aseptically adding 0.1 microgram of penicillin g per ... | 1983 | 6338827 |
| differential toxicity of inhaled gram-negative bacteria. | the toxicity by inhalation of various gram-negative bacteria, isolated from settings associated with inhalation disease, was studied by a variety of means. these microorganisms were not equally toxic. citrobacter freundii aerosol challenges of rabbits provoked significant (up to fivefold) increases in plasma haptoglobin 24 to 48 h after inhalation. other strains tested failed to provoke such statistically consistent increases. measurements of c-reactive protein in these same animals did not lead ... | 1983 | 6339400 |
| [the antibiotic agent azthreonam: studies on plasmid-dependent resistance formation]. | two mechanisms can be assumed that are responsible for the stability of azthreonam against the attack of beta-lactamases: first, azthreonam lacks binding to the enzyme protein and second, rate of hydrolysis is extremely low, resulting even in inhibition of enzyme activity. enzyme kinetics were studied from highly purified enzymes: azthreonam did not bind to the tem-1 enzyme, whereas the compound revealed a time-dependent inhibition of the chromosomally mediated enterobacter cloacae enzyme. with ... | 1983 | 6341212 |
| comparative activity of cefotetan on escherichia coli k12 possessing plasmid-mediated beta-lactamases. | the antibacterial activity of cefotetan, a new cephamycin, was compared with that of cephalothin, cefoxitin, cefamandole, cefoperazone and cefotaxime on 12 substrains of escherichia coli k12 bm13 harbouring single and multi-copy plasmids coding for plasmid-mediated beta-lactamases tem, shvi, oxa-i and oxa-iii. the 99% inhibitory concentrations (ic99) for the recipient strain were increased in proportion to the enzyme activity in the case of cefamandole and cefoperazone. in contrast, the activity ... | 1983 | 6341349 |
| the emergence of bacterial resistance and its influence on empiric therapy. | the discovery of antimicrobial agents had a major impact on the rate of survival from infections. however, the changing patterns of antimicrobial resistance caused a demand for new antibacterial agents. within a few years of the introduction of penicillin, the majority of staphylococci were resistant to that drug. in the 1960s the production of the semisynthetic penicillins provided an answer to the problem of staphylococcal resistance. in the early 1960s most escherichia coli were susceptible t ... | 1983 | 6342103 |
| plasmids encoding trimethoprim resistance in bacterial isolates from man and pigs. | trimethoprim (tp) resistant gram negative bacteria were isolated from humans and pigs. the bacterial hosts were characterized by their resistance pattern and biotype. the presence of transferable tp plasmids was demonstrated in 86% of 59 porcine isolates and 37% of 49 human isolates. the tp r-plasmids carried a diversity of resistance determinants such as tc, cm, sp, sm and su. incompatibility tests distinguished two major groups, inc fiv and inc n. thirty of 99 tp r-plasmids isolated from human ... | 1983 | 6343334 |
| phenomenon of resistance to augmentin associated with sensitivity to ampicillin: occurrence and explanation. | ampicillin was found to be some tenfold more active than amoxycillin against enterobacter cloacae. this finding explains the observation that some ent cloacae strains are sensitive to ampicillin in the disc test but resistant to augmentin. ampicillin was also found to be more active than amoxycillin against citrobacter freundii and serratia marcescens. in view of these findings, the practice of using ampicillin discs to predict sensitivity to amoxycillin should be reconsidered. the use of both a ... | 1983 | 6343436 |
| incompatibility group k plasmids in bacteria isolated from a urinary tract infection. | citrobacter freundii and klebsiella pneumoniae were concurrently isolated from a patient with a urinary tract infection. transferable drug resistant plasmids were isolated from both strains, pms434 and pms435. these plasmids belonged to incompatibility group k and both carried genes governing resistance to various aminoglycoside antibiotics, i.e., kanamycin, gentamicin c complex, streptomycin, and 3',4'-dideoxykanamycin b, in addition to those governing resistance to sulfanilamide and ampicillin ... | 1983 | 6346022 |
| [in vitro activity of azthreonam on hospital gram-negative bacilli. results of a multicenter study]. | this work reports a multicenter study of antibacterial activity of azthreonam, a new antibacterial agent of the monobactam group, on gram negative rods. enterobacteriaceae are very sensitive to azthreonam (modal mic: 0,06 micrograms/ml); some strains have higher mic greater than or equal to 8 micrograms/ml, particularly among enterobacter, serratia and citrobacter. azthreonam has a good activity on pseudomonas aeruginosa: 90% of the strains are inhibited by 8 micrograms/ml or less. acinetobacter ... | 1983 | 6348655 |
| [in vitro effect of rosoxacin on hospital bacteria. results of a multicenter study]. | this work reports a multicenter study of antibacterial activity of rosoxacin, a new antibacterial agent of the quinolone group. enterobacteriaceae are very sensitive to rosoxacin (modal mic 0,5 micrograms/ml); resistant strains are observed in all species, but more often among serratia and citrobacter. pseudomonas aeruginosa is less sensitive with a maximum number of strains between 2 and 8 micrograms/ml, so it is nearly for acinetobacter. haemophilus are very sensitive, having mic of 0,03 and 0 ... | 1983 | 6348657 |
| [transfer of resistance to antibiotics in dyspepsia in newborn infants]. | 1983 | 6349833 | |
| synthesis of plasmid-coded heat-labile enterotoxin in wild-type and hypertoxinogenic strains of escherichia coli and in other genera of enterobacteriaceae. | the effect of host determinants on expression of plasmid-coded heat-labile enterotoxin (lt) was examined. a collection of lt plasmids was introduced into isogenic strains of escherichia coli k-12 strains containing the wild type or hypertoxinogenic (htx-2) allele. for each plasmid tested, production of lt increased by approximately 1.5- to 3-fold in the host containing htx-2, indicating that the htx-2 allele affects a regulatory function for lt production that is common to many different enterot ... | 1983 | 6350177 |
| comparison of the overlapping frd and ampc operons of escherichia coli with the corresponding dna sequences in other gram-negative bacteria. | specific dna probes from escherichia coli k-12 were used to analyze the sequence divergence of the frd and ampc operons in various species of gram-negative bacteria. these operons code for the fumarate reductase complex and the chromosomal beta-lactamase, respectively. we demonstrate that the two operons show the same general pattern of divergence, although the frd operon is considerably more conserved than is the ampc operon. the major exception is salmonella typhimurium lt2, which shows a stro ... | 1983 | 6350266 |
| evaluation of the updated ms-2 bacterial identification system in comparison with the api 20e system. | the recently updated ms-2 bacterial identification system software (abbott laboratories, diagnostic division, irving, tex.) was compared with the original ms-2 bacterial identification software and the api 20e, using 968 strains of enterobacteriaceae. the updated ms-2 software correctly identified 94.4% of the isolates tested. api 20e and the original ms-2 software correctly identified 91 and 85.3% of the strains, respectively. ms-2 responses were considered to be equivocal (needing additional t ... | 1983 | 6350342 |
| early results of a comparative trial of ceftazidime versus cephalothin, carbenicillin and gentamicin in the treatment of febrile granulocytopenic patients. | ceftazidime was compared with a combination of cephalothin, carbenicillin and gentamicin as empirical therapy for fever in granulocytopenic patients. forty-eight patients were studied in this randomized trial. in the 44 evaluable cases, favourable clinical responses were seen in 9/21 ceftazidime-treated cases and 13/23 patients treated with the combination. four of 5 bacteraemias were cured with ceftazidime and 3 of 4 with triple therapy. comparable numbers of patients developed new fevers while ... | 1983 | 6352659 |
| [multicenter study of the in vitro antibacterial activity of ceftazidime on gram-negative bacilli]. | this work reports a multicenter study of antibacterial activity of ceftazidime, a new third generation cephalosporin, on hospital gram negative rods. enterobacteriaceae are very sensitive to ceftazidime with a maximum number of strains inhibited by 1 microgram/ml or less (modal mic 0, 125 microgram/ml); some resistant strains are observed, particularly among enterobacter and citrobacter. activity of ceftazidime on pseudomonas aeruginosa is superior to other third generation cephalosporins; modal ... | 1983 | 6353327 |
| [tem-type beta-lactamase coded by the plasmid from citrobacter sp]. | beta-lactamase was isolated from the cells of e. coli, strain 1039, a transconjugant carrying the plasmid first detected in citrobacter sp. beta-lactamase was purified to obtain a homogeneous preparation. the activity of the enzyme was estimated by a modification of the potentiometric method providing determination of up to 0.1 mumol of penicilloinic acid. the activity of the pure enzyme was 206 mumol per 1 mg of protein per minute. the molecular weight determined by gel filtration was 21500. th ... | 1983 | 6357063 |
| efficacy of brl 25000 against serratia marcescens, enterobacter cloacae, and citrobacter freundii in urinary tract infections. | synergism between amoxicillin and clavulanic acid was not expected against cephalosporinase-producing bacterial strains because clavulanic acid has little inhibitory action on cephalosporinases. however, in a clinical trial of brl 25000 (amoxicillin-clavulanic acid), excellent results were obtained in complicated urinary tract infections caused by serratia marcescens, enterobacter cloacae, and citrobacter freundii strains which produced cephalosporinase and were highly resistant to amoxicillin a ... | 1983 | 6357078 |
| [comparison of antibacterial potencies of oral and parenteral antibiotic preparations against escherichia coli, klebsiella, citrobacter, and proteus isolated from urinary tract infections (3: 1981) 1. susceptibility distribution]. | in vitro activities of antibacterial agents against e. coli, klebsiella, citrobacter and proteus which were isolated from patients with urinary tract infections at 8 hospitals in japan, were investigated by dilution broth method using mic 2000 (dynatec) during july to october in 1981. the summarized results are as follows: among oral antibacterial agents, mpc and ppa have showed potent antibacterial activities against e. coli and klebsiella. in vitro activities of oral antibacterial agents again ... | 1983 | 6361312 |
| [comparison of antibacterial potencies of oral and parenteral antibiotic preparations against escherichia coli, klebsiella, citrobacter, and proteus isolated from urinary tract infections (3: 1981). 2. changes in bacterial sensitivities]. | since 1979 the antibacterial activity of antibiotics against e. coli, klebsiella, citrobacter and proteus isolated from patients with urinary tract infections has been investigated. the serious transition of susceptibilities of e. coli and klebsiella could not be recognized in these antibiotics (mpc, abpc, na, ppa, cex, cez, ctm, cmz and cfx). however, a few resistant organisms against the third generation's antibiotics (ctx, cmx, czx, lmox and cpz) have already been appeared, we have to observe ... | 1983 | 6361313 |
| [comparison of antibacterial potencies of oral and parenteral antibiotic preparations against escherichia coli, klebsiella, citrobacter, and proteus isolated from urinary tract infections (3. 1981). 3. patient backgrounds and bacterial sensitivities]. | routine susceptibilities testing of microorganisms isolated from patients are of restricted usefulness in the treatment of patients because of the delay in obtaining results. thus, the empiric chemotherapy based on the susceptibility of microorganisms isolated from patients is necessary for the majority of patients with simple and complicated urinary tract infections. in this study the relation between changing susceptibility and background factors such as age, a sex distinction, antibiotics, ar ... | 1983 | 6361314 |
| influence of methoxy-substitution of beta-lactam compounds on the interaction with various beta-lactamases. | the interaction of 6 alpha-(temocillin) and 7 alpha-methoxy substituted (cefoxitin) beta-lactam compounds with various beta-lactamases was studied employing enzyme kinetics and compared to that of unsubstituted compounds. both chromosomally mediated enzymes from enterobacter cloacae and citrobacter freundii were competitively inhibited by the methoxy-substituted compounds. higher concentrations of cefoxitin caused a competitive inhibition of the plasmid-mediated tem-1 enzyme, whereas temocillin ... | 1983 | 6362278 |
| review of cefonicid, a long-acting cephalosporin. | the in vitro activity, pharmacokinetics, adverse effects, and clinical efficacy of cefonicid are reviewed. also discussed are formulary considerations and bacterial resistance. cefonicid, an investigational agent near approval, is less active than other currently available first- and second-generation cephalosporins against gram-positive cocci, particularly staphylococcus. cefonicid and cefamandole have similar activity that is superior to the first-generation cephalosporins against escherichia ... | 1984 | 6365414 |
| use of the autobac idx system for rapid identification of enterobacteriaceae and nonfermentative gram-negative bacilli. | the autobac idx system was evaluated for its ability to accurately identify 290 gram-negative bacilli from 18 different genera. excluding isolates with a low identification probability, the overall sensitivity of the system was found to be 95.8%. late lactose-fermenting escherichia coli, citrobacter freundii, and proteus mirabilis accounted for over 90% of the misidentifications. the autobac idx system offers a rapid and reliable method for the identification of gram-negative bacilli. | 1984 | 6365967 |
| the bacterial flora of fruits and vegetables in lebanon and the effect of washing on the bacterial content. | washed and unwashed vegetables and fruit specimens including radish, lettuce, mint, carrots, parsley, strawberries, green almond, akadinya, green-gages, cherries, plums, peaches, pears, and apples were investigated for their bacterial content. tested specimens had a high content of bacteria belonging to the genera enterobacter, citrobacter, klebsiella, proteus, pseudomonas, providencia, escherichia, staphylococcus, and salmonella. the washing procedure followed was effective in reducing the numb ... | 1983 | 6367304 |
| investigations on beta-lactamase stability of recently developed beta-lactam compounds: study of enzyme kinetics. | the plasmid-mediated tem-1 enzyme (e. coli k12 r6k) and chromosomally mediated enzymes from enterobacter cloacae (iep 8.5) and citrobacter freundii (iep 9.5) were highly purified. enzyme kinetics were studied with various therapeutic compounds as substrates and lamoxactam, azthreonam, and n-formimidoyl thienamycin as inhibitors. lamoxactam and azthreonam failed to inhibit the tem-1 enzyme, whereas n-formimidoyl thienamycin was a competitive inhibitor. ki was 5 mumol/l--thus corresponding to km-- ... | 1983 | 6372325 |
| novel carbapenem derivative sf2103a: studies on the mode of beta-lactamase inactivation. | a novel carbapenem, sf2103a, is a strong inhibitor of various types of beta-lactamase. equimolar concentrations of sf2103a completely inactivated the cephalosporinases of proteus vulgaris and citrobacter freundii and type ib and type ii penicillinases mediated by r plasmids in a progressive manner. the inactivation of the two penicillinases and p. vulgaris cephalosporinase was apparently irreversible; however, when the inactivated enzymes were separated from excess sf2103a by gel filtration, the ... | 1984 | 6372682 |
| resistance types in citrobacter freundii. occurrence and resistance to ampicillin, carbenicillin, cephalothin and mecillinam. transfer of ampicillin resistance. | the resistance types of citrobacter freundii were investigated. the strains were divided into three groups according to susceptibility to penicillin derivatives. group 1, comprising the ampicillin-carbenicillin sensitive strains (a-s/ca-s), constituted 22%. group 2 (ampicillin-resistant (a-r)/ca-s) constituted 45% and group 3 (a-r/ca-r) 32%. two strains (1%) were recorded as a-s/ca-r. group 3 contained a higher proportion of multi-resistant strains than groups 1 and 2. the log2ic50 with ampicill ... | 1984 | 6375251 |
| [enzyme activity of the formate hydrogenlyase complex in citrobacter freundii]. | citrobacter freundii 62 can grow in the absence of oxygen in media containing glucose, peptone, fumarate or malate. when the medium contained fumarate or malate, the culture could grow under anaerobic conditions only in the presence of molecular hydrogen, formate or nitrate. the highest activity of formatehydrogenlyase and hydrogenase was found when c. freundii grew in a medium with glucose and formate. the activity was lower in media with other organic substrates, particularly, in the absence o ... | 1984 | 6377026 |
| [pathogen distribution in waste water sprinkler irrigation]. | the spray irrigation with pretreated wastewater was investigated on the sewage farm of the braunschweig sewage utilization association. the emission of airborne bacteria was measured by means of andersen sampler (as), reuter centrifugal sampler (rcs), and sedimentation plates (sp). there was a good correlation of results obtained by parallel measurings of as and rcs. the rcs was more effective by the factor 11.5 than the as sampling airborne microorganisms. however, the as gaves the distribution ... | 1984 | 6377753 |
| approach to hospital-acquired pneumonias. | 1984 | 6381413 | |
| effect of noncoliforms on coliform detection in potable groundwater: improved recovery with an anaerobic membrane filter technique. | a total of 529 well and distribution potable water samples were analyzed for total coliforms by the most-probable-number and membrane filter (mf) techniques. standard plate count bacteria and mf noncoliform bacteria were also enumerated. frequency of coliform detection, turbidity in most-probable-number tubes, and extensive overgrowth by noncoliforms on mf filters were directly proportional to standard plate counts. recovery of coliforms was greatest by the mf method at low (less than 100 cfu/ml ... | 1984 | 6383216 |
| intergeneric homology of the spec gene encoding biosynthetic ornithine decarboxylase in escherichia coli. | a 32p-labeled fragment of dna containing the spec gene, which encodes the biosynthetic enzyme ornithine decarboxylase of escherichia coli, was used as a hybridization probe for homologous sequences in the genomes of gram-negative and gram-positive bacteria. the spec probe detected homologous sequences in the dna of only four members of the enterobacteriaceae (citrobacter freundii, salmonella typhimurium, klebsiella pneumoniae, and enterobacter aerogenes); no homology was detected with the dna of ... | 1984 | 6384181 |
| [enterotoxigenicity and neuraminidase activity of bacteria of the genus citrobacter]. | the data obtained in the study of citrobacter strains isolated from patients with diarrheal diseases and from healthy persons are presented: enterotoxigenicity was studied in 68 strains, while neuraminidase activity in 41 strains. among the strains of these groups 9 strains with active enterotoxin and 2 strains producing active neuraminidase were detected. the criteria for subdividing citrobacter strains according to the activity of their thermolabile enterotoxin are proposed. | 1984 | 6385584 |
| cephalosporin antibiotics as applied in surgery of bones and joints. | new cephalosporin antibiotics will continue to be discovered as old forms are found to lose effectiveness. cephalosporins currently account for a major part of any hospital pharmacy budget. they are often used inappropriately in treatment of both community and hospital infections. cephalosporins should be used when penicillins are not effective and for particular infections. a major use of cephalosporins is in prophylaxis; cephalosporin antibiotics will not prevent infections caused by organisms ... | 1984 | 6386261 |
| incidence of trimethoprim-sulfamethoxazole-resistant enterobacteriaceae among transplant recipients. | of 114 recipients of pancreatic, renal, and bone marrow transplants who were given trimethoprim-sulfamethoxazole (tmp-smz) for antimicrobial prophylaxis, 44 (39%) had a total of 52 fecal isolates of tmp-smz-resistant gram-negative bacilli. in most of these 44 patients, the resistant isolate was found at a concentration of greater than or equal to 10(6) organisms/ml of feces. escherichia coli was the most frequent of the isolates, and citrobacter freundii was the next most frequent. eight of the ... | 1984 | 6387000 |
| in-vitro activity of ciprofloxacin (bay 09867) | 1984 | 6389471 | |
| evaluation of rosco diagnostic beta-glucuronidase tablets in the identification of urinary isolates of escherichia coli. | rosco diagnostic beta-glucuronidase tablets have been evaluated as a method for the identification of urinary isolates of escherichia coli. results were compared with those from traditional biochemical testing. a total of 539 isolates were employed, representing a variety of gram-negative species. reproducibility testing was also performed. after 4h incubation, 86% of e. coli isolates (both lactose-positive and lactose-negative) gave a positive reaction. some salmonella, many shigella and one ci ... | 1984 | 6393708 |
| septicemia due to a lactose-fermenting salmonella misidentified as citrobacter freundii. | 1984 | 6394546 | |
| monoclonal antibody-based enzyme-linked immunosorbent assays for identification and serotyping of vibrio cholerae o1. | monoclonal antibodies directed against o-specific antigens of vibrio cholerae o1 lipopolysaccharide were used in two different enzyme-linked immunosorbent assays (elisas), designed for identification and serotyping of v. cholerae o1. in the sandwich elisa, a monoclonal antibody against the group-specific antigen was used as capture antibody, whereas peroxidase-conjugated monoclonal antibodies directed against group- and type-specific antigens were used as the second antibodies. monoclonal antibo ... | 1984 | 6394621 |
| comparative efficacy of piperacillin versus carbenicillin for complicated urinary tract infections. | in this controlled, randomized clinical trial we compared piperacillin and carbenicillin in the treatment of complicated urinary tract infections. 24 patients received piperacillin 150 mg/kg/day for 7.2 +/- 2.75 days and 17 patients received carbenicillin 200 mg/kg/day for 7.5 +/- 2.90 days. patients were evaluated for clinical and bacteriologic responses and tolerance to therapy. although the clinical cure rate significantly favored carbenicillin treatment (p less than 0.01), the sum of the per ... | 1984 | 6395464 |
| complications of citrobacter neonatal meningitis: assessment by real-time cranial sonography correlated with ct. | real-time cranial sonography via the anterior fontanelle was used serially over a 3- and 6-week period, respectively, to evaluate two infants who developed multicystic encephalomalacia secondary to citrobacter neonatal meningitis. sonographic findings included heterogeneous parenchymal echogenicity, gyral prominence, periventricular hypoechoic areas from which cystic spaces evolved, and development of hydrocephalus. serial cranial computed tomography over the same time period confirmed the sonog ... | 1983 | 6410827 |
| selection of variants of gram-negative bacteria with elevated production of type 1 beta-lactamase. | variants of pseudomonas aeruginosa, citrobacter freundii and enterobacter cloacae were isolated that produced elevated levels of type 1 beta-lactamase. the variants were readily isolated on antibiotic-containing agar and showed resistance to a wide range of beta-lactam antibiotics including some regarded as being relatively stable to the beta-lactamase produced. | 1983 | 6411674 |
| [bacteriostatic activity of apalcillin on gram-negative bacilli and strict anaerobic bacteria. multicenter study]. | this work reports a multicenter study of the bacteriostatic activity of apalcillin, a new n-acyl-penicillin, against 1 827 clinical isolates of gram-negative bacilli and obligate anaerobes. the modal minimal inhibitory concentrations (mics) for susceptible strains are (mg/l) : salmonella-shigella : 1 ; e. coli : 0.5-2 ; klebsiella : 4 ; citrobacter : 1-2 ; enterobacter : 2 ; serratia : 8 ; proteus-providencia : 1 ; acinetobacter : 1-4 ; p. aeruginosa : 2 ; h. influenzae : 0.06 ; c. perfringens : ... | 1984 | 6429608 |
| gastrointestinal illness associated with imported brie cheese--district of columbia. | 1983 | 6431243 | |
| [sensitivity to fosfomycin of bacteria isolated at the pitié-salpétrière hospital in 1982 and 1983]. | susceptibility of 16 056 strains isolated in 1982 and 1983 to fosfomycin (fos) was tested with mueller-hinton medium and discs 50 micrograms fos + 25 micrograms glucose-6-phosphate (g6p) (cutoff diameter 14 mm). for 3 411 strains, inhibition zone diameters were recorded. almost all e. coli, citrobacter, salmonella and s. aureus were susceptible to fos as well as 70% of serratia, e. cloacae, p. mirabilis and 50% of klebsiella and enterobacter sp. only 27% of p. aeruginosa, 20% of indole positive ... | 1984 | 6431379 |
| in vitro properties of ceftazidime, a highly active broad-spectrum cephalosporin with antipseudomonal activity. | ceftazidime is an aminothiazolyl cephalosporin that exhibits a high level of broad-spectrum activity, with particularly good activity against pseudomonas sp. although activity in vitro against staphylococci is moderate, the majority of enterobacteria are susceptible, with mic50 values in the range from 0.06 to 4 micrograms/ml. this cephalosporin is also highly active against indole-positive proteus sp, providencia sp, citrobacter sp, and serratia sp, with mic50 values ranging from less than or e ... | 1984 | 6432324 |
| third-generation cephalosporins: a critical evaluation. | six third-generation cephalosporins--cefotaxime, moxalactam, cefoperazone, ceftizoxime, ceftriaxone, and cefmenoxime--are reviewed; covered are chemistry and structure-activity relationships, mechanism of action, spectra of activity, pharmacokinetics, clinical utility, adverse effects, and cost effectiveness. the third-generation cephalosporins have a similar mechanism of action to that of other beta-lactam antibiotics. none of the agents is particularly active against certain gram-positive bact ... | 1984 | 6432420 |
| [comparative studies of antimicrobial agents against causative organisms isolated from urinary tract infections (1982). iii. secular changes in susceptibility]. | in vitro susceptibilities have been investigated against several species isolated from patients with simple and complicated urinary tract infections (uti) during 1980-1982. antimicrobial activities of the third generation cephems against e. coli isolated from patients with complicated uti were found to decrease slightly in 1982. and those against klebsiella spp. isolated from patients with simple and complicated uti were also found to decrease similarly. against p. mirabilis, all the drugs teste ... | 1984 | 6433065 |
| [in vitro antibacterial activity of ciprofloxacin against uropathogenic organisms]. | ciprofloxacin (bay 09867) is a new quinoline derivative. its activity against 537 urinary bacterial isolates was compared with those of ampicillin, amikacin, carbenicillin, cefazolin, cefotaxime, cefoxitin, ceftazidime, nalidixic and oxolinic acids, norfloxacin, trimethoprim, and other antimicrobial agents, when appropriate. it inhibited 90% citrobacter freundii, enterobacter spp., e, coli, klebsiella spp., proteus spp., and serratia spp. at less than or equal to 0.78 microgram/ml. the majority ... | 1984 | 6440583 |
| inhibitory and bactericidal activities of amifloxacin, a new quinolone carboxylic acid, compared with those of seven other antimicrobial agents. | the activity of amifloxacin, a new quinolone carboxylic acid compound, against 147 strains of microorganisms was studied and was compared with the activities of cinoxacin, trimethoprim, amikacin, and four beta-lactam antimicrobials. the minimal concentration at which 90% of strains were inhibited by amifloxacin was lowest for escherichia coli and klebsiella sp (less than or equal to 0.125 microgram/ml), followed by proteus sp (less than or equal to 0.25 microgram/ml), enterobacter sp and citroba ... | 1984 | 6440708 |
| [clinical significance of citrobacter isolates]. | 1984 | 6440918 | |
| effect of hyperbaric oxyhelium gas on response of bacteria to antimicrobial agents in vitro. | modern diving techniques can require the treatment of infection in an atmosphere of pressurized oxyhelium gas. the antibiotic susceptibility of 16 species and strains (eight genera) of gram-negative bacilli and 3 species and strains (two genera) of gram-positive cocci to each of 21 antimicrobial agents was assessed in air at atmospheric pressure and in oxyhelium gas at an absolute pressure of 7 bar (ca. 709 kpa). a disk diffusion technique was employed, and significantly different results were o ... | 1984 | 6441512 |
| [concept of class in relation to first-generation cephalosporins]. | the authors consider differences in answer of the first generation cephalosporins against several strains of gram-negative and gram-positive bacteria, and suggest a revision of the "class" concept as regards sensitivity response of the above mentioned cephalosporins. | 1984 | 6441962 |
| recognition and clinical significance of mechanisms of bacterial resistance to beta-lactams. | resistance to beta-lactams may be difficult to recognize. this is due to the difficulty in detecting these resistances, when the routine tests performed in diagnostic laboratories are interpreted in the usual manner. since failure to recognize this type of resistance may have serious consequences for the patient, it is essential that it be detected when present. for the detection of methicillin resistance of staphylococcus aureus a standardized method using either a medium containing 5% nacl or ... | 1984 | 6442123 |
| citrobacter accumulates heavy metals. | 1984 | 6444096 | |
| conservation and variation of nucleotide sequences within related bacterial genomes: enterobacteria. | we have assessed the degree of relatedness of several portions of the escherichia coli genome to the corresponding portions of the genomes of representative enteric bacteria, using the southern transfer and hybridization technique (e. southern, j. mol. biol. 98:503-517, 1975). the degree of relatedness varied among the regions examined. judging both by the relative amounts of deoxyribonucleic acid in the various enteric genomes that are highly homologous and by the conservation of positions of r ... | 1980 | 6447143 |
| pharmacokinetics and bacteriological efficacy of moxalactam (ly127935), netilmicin, and ampicillin in experimental gram-negative enteric bacillary meningitis. | moxalactam (ly127935) is a 1-oxa-beta-lactam which was active in vitro against the majority of 128 strains of gram-negative enteric bacilli isolated from meningitis in neonates. pharmacokinetics and bacteriological efficacy of ly127935 were studied in a lapin meningitis model. the average penetration of this investigational oxa-cephalosporin into cerebrospinal fluid of infected rabbits was 23% compared with 25% for netilmicin and 11% for ampicillin. the cerebrospinal fluid concentrations of ly12 ... | 1980 | 6448576 |
| introduction of bacteriophage mu into bacteria of various genera and intergeneric gene transfer by rp4::mu. | the host range of coliphage mu was greatly expanded to various genera of gram-negative bacteria by using the hybrid plasmic rp4::mu cts, which is temperature sensitive and which confers resistance to ampicillin, kanamycin, and tetracycline. these drug resistance genes were transferred from escherichia coli to members of the general klebsiella, enterobacter, citrobacter, salmonella, proteus, erwinia, serratia, alcaligenes, agrobacterium, rhizobium, pseudomonas, acetobacter, and bacillus. mu phage ... | 1981 | 6450749 |
| correlation of moxalactam (ly127935) susceptibility tests by disk diffusion and agar plate dilution methods. | susceptibility of pathogenic aerobic bacteria to moxalactam (ly127935) was compared by two methods, diffusion from 30-microgram disks and agar plate dilution. the two methods gave a satisfactory degree of correlation when compared by linear regression, but the slope of the linear regression was significantly steeper for gram-negative bacilli (enterobacteriaceae and pseudomonas aeruginosa) than for coccal organisms (streptococci and staphylococci). the largest zone diameters by disk diffusion wer ... | 1981 | 6454380 |
| biosynthesis and export of colicin a in citrobacter freundii ca31. | synthesis of colicin a after induction with mitomycin c was studied. specific inhibition of chromosomal protein synthesis occurred very shortly after mitomycin addition. there was no coordinate synthesis of colicin a (61000 mr) and low-molecular-weight protein. free and membrane-bound polysome fractions were isolated from cells induced with mitomycin c. colicin a is synthesized in vitro in the free polysomes and not in the membrane-bound polysomes. conditions are described which allow a practica ... | 1981 | 6455292 |
| hypoprothrombinemia associated with moxalactam treatment of a septic sternoclavicular arthritis due to citrobacter diversus. | 1981 | 6456139 | |
| citrobacter meningitis and cerebral abscess in early infancy: cure by moxalactam. | a 7-week-old boy developed multiple cerebral abscesses as a complication of neonatal citrobacter diversus meningitis. he was successfully treated medically with the experimental beta-lactam antibiotic, moxalactam. this is the first nonsurgical cure of brain abscess in early infancy. fifty-eight percent of all previously reported cases of citrobacter meningitis were complicated by brain abscess, mandating early, and serial computed tomography scanning in patients afflicted with the disorder. moxa ... | 1981 | 6458777 |
| [comparative in vitro activity of 5 semi-synthetic penicillins against aerobic gram-negative bacilli and enterococci (author's transl)]. | the mics and mbcs of mezlocillin, ticarcillin and piperacillin were determined by microdilution in liquid medium against 700 strains of gram-negative bacilli and enterococci isolated from pathological materials and classified according to their sensitivity of ampicillin and carbenicillin. strains sensitive to ampicillin and carbenicillin were usually sensitive to the other penicillins with weight for weight differences in activity. the mic pf mezlocillin against 40% of ampicillin - and carbenici ... | 1982 | 6460967 |
| [dibekacin in the treatment of urinary infections in the elderly]. | urinary tract infections in the elderly are severe and intractable, often justifying the use of aminoglycosides. we studied the effects of dibekacin in 28 patients, with no vesical catheter, whose average age was 78 +/- 6.1 years. the drug was given for ten days, in an average dose of 2.1 mg/kg/day divided into two injections. serum concentration was measured after one hour on day 1 and after eight hours on days 1 and 10. causative pathogens, all susceptible to dibekacin, were: 18 e. coli, 3 pro ... | 1984 | 6462747 |
| nosocomial meningitis due to citrobacter diversus in neonates: new aspects of the epidemiology. | two term neonates born within four days of each other at a small hospital developed sepsis and meningitis caused by a unique strain of citrobacter diversus not previously reported to cause meningitis. eleven (27.5%) of 40 other infants admitted to the nursery during the epidemic period developed rectal or umbilical colonization by c. diversus. contact soon after birth with either of two nurses was more common among infected or colonized infants than among infants who were not infected or coloniz ... | 1984 | 6470529 |
| [comparative studies of antimicrobial agents against causative organisms isolated from urinary tract infections (1982). ii. background of patients]. | the frequency of the causative strains in urinary tract infections was investigated from the point of view of the patient's background such as age, sex administration of antibiotics and so on. especially, the frequency of the causative strains isolated from patients within 3 days after the administration of antibiotics has markedly decreased. however, the frequency of the resistant strains such as p. aeruginosa, enterobacter spp., citrobacter spp. and serratia spp. has increased after 8 days' ad ... | 1984 | 6471384 |
| growth of clinical isolates in the cold. | common clinical isolates were tested to determine their ability to multiply after 7 days at 4 degrees c in trypticase soy broth. 34% of the 214 isolates grew in the cold. citrobacter freundii, group d enterococci, klebsiella oxytoca, proteus vulgaris, providencia rettgeri and serratia marcescens grew best of all. the importance of growth in the cold is discussed. | 1984 | 6472199 |
| [distribution of enterobacteria in soil following irrigation with waste water]. | the filtration of wastewater after irrigation by sandy soil in the area of the braunschweig sewage utilization association was investigated. for that purpose, the concentrations of gram-negative aerobe rods were determined in soil samples of 15 cm, 30 cm, 45 cm, 60 cm, 75 cm, 90 cm, 105 cm, 120 cm, 135 cm, and 150 cm depth immediately after an irrigation of about 50 mm wastewater during the vegetation (3 series), the vegetationless period (6 series), after one week (3 series) and after two weeks ... | 1984 | 6475379 |
| microbial aspects of the cockroach hindgut. | the cockroach hindgut has a complex, active microbiota, a large portion of which is associated with the chitinous gut wall. it provides a different environment from that of termites and other insects which are dependent on their hindgut microbiota for the digestion of cellulose. the ph of the midgut of eublaberus posticus was not as high as it is in insects with a primarily cellulolytic nutrition. the hindgut of e. posticus was highly methanogenic, normal adults producing typically 10-25 mumol o ... | 1984 | 6477029 |
| survey of resistance to metals and volatilization activity of hg-resistant r plasmids in citrobacter isolated from clinical lesions in japan. | clinical isolates of citrobacter (277 strains) were studied for the resistance to four metals and four drugs. the distribution patterns of their susceptibility to hg, cd and as clearly revealed two peaks, but only a single peak of resistance to pb. the frequencies of resistance to hg, cd, as, sm, tc, cp and km were 31.8, 94.2, 57.8, 51.3, 44.8, 35.7 and 28.9%, respectively. and we selected 88 mercury resistant strains, and they were tested for their ability to transfer the resistance to the merc ... | 1984 | 6485637 |
| do we need the third-generation cephalosporins? | third-generation cephalosporins have been available for the past 5 years. the continued increase in resistance of bacteria to older antimicrobial agents and the safety profile of a number of the third-generation agents have established situations in which these compounds are useful. upper respiratory infections such as epiglottitis, lower respiratory tract infections due to enterobacteriaceae are examples of illnesses in which third-generation cephalosporins would be preferred to older drug prog ... | 1984 | 6501133 |
| survey of the phenotypes of susceptibility to beta-lactams in enterobacteriaceae at the pitie-salpetriere hospital. | the phenotypes of susceptibility to ampicillin, carbenicillin, cephalothin, cefamandole, cefoxitin and cefotaxime were determined by the disc-diffusion method in 10,994 enterobacteriaceae consecutively isolated from in-patients during 18 months. the susceptible phenotypes were much more frequent among escherichia coli, proteus mirabilis and klebsiella (67.4 to 84.8%) than among serratia, enterobacter and citrobacter (8.8 to 35.5%). in all species the most common resistance phenotypes were to amp ... | 1984 | 6501135 |
| [study of lincomycin concentrations in hepatocystic duct]. | penetration of lincomycin (lcm) in choledochal and cholecystic bile as well as in the gallbladder tissue and liver tissue was investigated together with bacteria detectable in the bile in order to evaluate basically usefulness of this antibiotic in the treatment of infections of the hepatocystic duct. intravenous drip infusion of lcm 1.5 g (in 500 ml of 5% glucose solution) over 1.5--2 hours resulted in mean drug concentrations of 33.9 and 10.1 micrograms/ml in serum at 2 and 4 hours post start ... | 1984 | 6502929 |
| cefoperazone in the treatment of postsurgical wound infection, sepsis, and abscess of the spinal cord and brain. | cefoperazone was used in the treatment of 23 cases of serious bacterial infection in 20 patients. ten postoperative scalp wound infections, five infections at the site of tracheostomy, four cases of extradural spinal cord abscess, three cases of sepsis, and one abscess of the cerebellopontine angle were treated with cefoperazone (1 to 2 gm bid, usually for seven to 27 days). there were excellent or good clinical responses in 87% (20/23) of the cases (14 of the 15 postsurgical wound infections, t ... | 1984 | 6509463 |
| citrobacter koseri isolated in israel, 1972-83. | cultures of citrobacter koseri (syn. c. diversus), an opportunistic pathogen that was isolated in israel during 1972-83, were studied by sero- and biotyping and for susceptibility to antibacterial agents. of 1,172 cultures, 96% were isolated from adults, more than half from urinary tract infections. other frequent sources were superficial wounds and discharges from the respiratory and genital tracts. seventeen strains originated from blood cultures of patients with sepsis and four from the cereb ... | 1984 | 6511332 |
| degradation of citrobacter o-serogroup ci23vi+ murein with vi phages. | dialysable products resulting from the digestion of the citrobacter o-serogroup ci23vi+ murein with vi phages show a decrease of their reducing power/muropeptides. it is accompanied with an increase of free amino groups amount/muropeptide when compared to the one obtained after the lysozyme treatment. it leads to a suggestion, that vi phage particles possess two enzyme activities: "lysozyme-like" and deacetylase which might be a transacetylase. | 1984 | 6524155 |
| neonatal citrobacter meningitis: pathogenesis of cerebral abscess formation. | in 2 premature infants with brief survival, the major pathological feature of citrobacter meningitis consisted of vasculitis and infarction with necrosis and liquefaction of large portions of the white matter of the hemispheres. areas of decreased density demonstrated on computed tomographic head scan represented infarction with necrosis, liquefaction, and cavitation and not a classic abscess. this finding has clinical significance, because surgical drainage of liquefied infarcts is rarely indic ... | 1984 | 6524874 |
| in vitro antibacterial activity of thiamphenicol. | this in vitro study of thiamphenicol activity against 247 strains of gram-positive and 195 strains of gram-negative pathogenic bacteria showed no significant changes from past activity. of the 442 strains involved, thiamphenicol proved: - effective (mic = less than or equal to 0.5-4 micrograms/ml) against 131 strains, mostly streptococci, pneumococci and enterococci. - moderately effective (mic = 8-64 micrograms/ml) against 252 strains, mostly staphylococci, salmonella, citrobacter, k. pneumonia ... | 1984 | 6529771 |
| immunochemical characterization of lipopolysaccharides of citrobacter chemotypes cc-g and cc-h. | lipopolysaccharides of citrobacter serotypes 04, 027 and 036 indicate strong cross-reactivity in passive hemagglutination and their o-specific chains are homopolymers of (beta 1----2)--linked 4-deoxy-d-arabinohexose. citrobacter serotype 023 cannot be placed in chemotype cc-h, since its o-specific polysaccharide does not contain 4-deoxy-hexose. the possibility exists that 4-deoxy-d-arabinohexosyl side chains of 023-specific-polysaccharide disappeared as a result of a mutation of the parent strai ... | 1984 | 6534318 |