Publications

lyme disease.		1989	2758818
the epidemiology of lyme disease in connecticut.	the overall incidence for lyme disease for connecticut residents in 1988 was 22 per 100,000. the highest rates were among residents of new london (108 per 100,000) and middlesex counties (72 per 100,000), although the greatest increase in incidence between 1985 and 1988 occurred among residents of fairfield county (2 per 100,000 in 1985, 14 per 100,000 in 1988). lyme disease is a statewide problem; in 1988 cases were reported among residents of 104 of connecticut's 169 towns and cities. the dise ...	2009	2758819
national surveillance of lyme disease, 1987-1988.	in 1987 and 1988, 6876 lyme disease cases from 43 states were reported to the centers for disease control. the 4507 cases reported in 1988 was nearly double the case number reported in 1987, and ninefold the number reported in 1982, when a systematic system of national surveillance was established. the average annual incidence of reported lyme disease in the united states in 1987-1988 was 1.4/100,000. new york led the nation in reported cases in 1988 with 57% of the cases reported nationally. ei ...	1989	2758820
a prospective study of tick bites in an endemic area for lyme disease.		1989	2758821
lyme disease and pregnancy.		1989	2758822
lyme disease prevention--knowledge, beliefs, and behaviors among high school students in an endemic area.	we surveyed 153 high school students in an area highly-endemic for lyme disease. all students were familiar with lyme disease; 14 students reported having had the disease. ninety per cent of students believed tick-avoidance behavior could prevent lyme disease, but fewer than half reported practicing any preventive behaviors. students who believed a specific behavior was preventive were 3-6 times more likely than others to practice that behavior. schools in endemic areas should educate students a ...	2009	2758823
sharing the task of lyme disease. public education.		1989	2758825
legal implications of uncertainty in lyme disease.		1989	2758826
practicing in lyme disease territory.		1989	2758828
lyme disease and antibiotic prophylaxis.		1989	2758829
reinfection with borrelia burgdorferi.		1989	2758830
lyme disease.		1989	2758859
[unusual manifestations of lyme borreliosis. a contribution to the clinical spectrum of this disease group].	since the discovery that em (erythema migrans), aca (acrodermatitis chronica atrophicans) and bl (borrelial lymphocytoma) have an infectious etiology, these syndromes have been receiving particular attention. this report describes four patients whose dermatological symptoms did not at first indicate borreliosis. in all four cases serological antibody tests proved that they were caused by borrelia burgdorferi. in two of these cases these findings were confirmed by bacterial cultures. the unusual ...	1989	2759856
lameness and asymptomatic borrelia burgdorferi seropositivity in dogs.		1989	2760490
analysis of north american and european isolates of borrelia burgdorferi with antiserum to a recombinant antigen.		1989	2760492
adherence of the lyme disease spirochete to glial cells and cells of glial origin.	lyme disease, a tick-borne spirochetosis caused by borrelia burgdorferi, produces protean neurologic manifestations, yet its neuropathogenesis is poorly understood. the affinity of the spirochete for cells of primary rat brain cultures and of the c6 glioma cell line was studied. b. burgdorferi adhered to both types of cells in a dose-dependent manner and exhibited an affinity for an extracellular matrix produced by the primary and by glioma cell cultures. adherence of the spirochetes to the glia ...	1989	2760500
locked-in state in borrelia burgdorferi meningitis.	the case is reported of a 28-year-old woman with persistent tetraplegia following acute meningitis due to borrelia burgdorferi infection. the patient developed erythema chronicum migrans before radicular pain occurred in the upper extremities. the poor clinical outcome was suggestive of pontine infarction due to vasculitis of branches of the basilar artery.	1989	2760649
molecular analysis of linear plasmid-encoded major surface proteins, ospa and ospb, of the lyme disease spirochaete borrelia burgdorferi.	the ospa and ospb genes encode the major outer membrane proteins of the lyme disease spirochaete borrelia burgdorferi. the deduced translation products from the ospa and ospb genes were: (ospa) 273 amino acids long with a molecular weight of 29,334, and (ospb) 296 amino acids long with a molecular weight of 31,739. the two osp proteins showed a great degree of sequence similarity indicating a recent evolutionary event. molecular analysis and sequence comparison of ospa and ospb with other protei ...	1989	2761388
megabase-sized linear dna in the bacterium borrelia burgdorferi, the lyme disease agent.	using pulsed-field gel electrophoresis we examined the genome of borrelia burgdorferi, a eubacterium of the spirochete phylum and the agent of lyme disease. a population of this species' cells was lysed in situ in agarose blocks. an abundant dna form that behaved as a linear duplex molecule under different electrophoretic conditions was found. the estimated size of the molecule was 950 kilobases. dna from two other genera of spirochetes did not enter the gel under these conditions. these studies ...	1989	2762306
late stage lyme borreliosis in children.	these cases illustrate that late stage lyme borreliosis can occur in children without a history of tick bite or ecm; this disorder can manifest itself initially as a seventh cranial nerve palsy, heart block, or arthritis, and the arthritis syndrome can mimic oligoarticular juvenile rheumatoid arthritis. the diagnosis of lyme borreliosis depends upon clinical recognition. in the absence of ecm, tests for antibodies to borrelia burgdorferi can provide an invaluable tool in assisting in the diagnos ...	1989	2762902
complete heart block as the sole presentation of lyme disease.	we report a case of lyme myocarditis presenting solely as complete heart block in a previously healthy 32-year-old white man. indium cardiac antimyosin scan showed diffuse uptake (2+, on a scale of 0 to 4+) during the acute phase of the illness. the electrocardiogram and the indium cardiac antimyosin scan were normal 6 weeks after completion of tetracycline and prednisone treatment. lyme carditis should be considered in the differential diagnosis of complete heart block of unclear origins, even ...	1989	2764661
lyme myocarditis diagnosed by indium-111-antimyosin antibody scintigraphy.	we report a new case of lyme disease with cardiac manifestations, which has been possible to follow during the long period of 12 years. we have detected the usual ecg abnormalities, and concentric hypertrophic myocardiopathy, by echocardiography. the acute myocarditis was demonstrated by 111in-antimyosin scintigraphy, which showed global myocardial uptake of the tracer, constituting the first report, to our knowledge, of lyme myocarditis diagnosed by this method.	1989	2767084
[limb and joint pain in lyme disease. an important differential neurologic diagnosis].	on the basis of 4 cases, attention is drawn to the problem of early detection of lyme disease. the occurrence of joint pain with fluctuating spread and unresponsive to the usual antiinflammatory therapy should prompt the physician to consider lyme disease, which can be confirmed or excluded only by lumbar puncture. the csf shows a cell count of between 300/3 and 2,000/3 cells (90% lymphocytes) and usually moderately elevated protein. a demonstration of elevated antibody titers confirms the diagn ...	1989	2767602
a tick, in time, may cause lyme (disease).		1989	2768012
ear punch biopsy method for detection and isolation of borrelia burgdorferi from rodents.	an ear punch biopsy method for the detection and isolation of borrelia burgdorferi from rodents was developed. the ear punch biopsy proved to be extremely sensitive, detecting spirochetes in 100% (11 of 11) of laboratory hamsters infected by tick bite and 95.8% (23 of 24) of hamsters infected by intraperitoneal inoculation. when cultured at 4 to 6 weeks postinfection, 92 to 100% of the ear punches taken from individual hamsters yielded viable spirochetes. b. burgdorferi was detected in sequentia ...	1989	2768461
identification of borrelia burgdorferi and b. hermsii using dna hybridization probes.	fragments of plasmid dna from borrelia burgdorferi and b. hermsii were cloned and tested for specificity as hybridization probes to identify these two species of pathogenic spirochetes. three fragments from the 49-kilobase-pair linear plasmid of b. burgdorferi were tested: a 500-base-pair (bp) hindiii fragment (probe 49a), a 445-bp psti-hindiii fragment (probe 3g), and a 320-bp hindiii fragment (probe 16h). when hybridized to purified dna or whole spirochetes, all of the probes distinguished b. ...	1989	2768462
lyme disease in california: interrelationship of ixodes pacificus (acari: ixodidae), the western fence lizard (sceloporus occidentalis), and borrelia burgdorferi.	the relationship of immature western black-legged ticks, ixodes pacificus cooley and kohls, to the western fence lizard, sceloporus occidentalis baird and girard, and to the lyme disease spirochete, borrelia burgdorferi, was investigated in chaparral and woodland-grass habitats in northern california from 1984 to 1986. immature ticks were found on lizards in spring and summer, but the prevalence and abundance of ticks on this host were considerably greater in spring. the peak of larval abundance ...	1989	2769705
[meningoradiculitis caused by borrelia burgdorferi].		1989	2772302
[lyme disease with a 12-year course and serologic diagnosis].		1989	2772332
survival of borrelia burgdorferi in blood products.	the incidence of lyme disease is rapidly increasing in the united states. to assess the potential of transmission of the disease through blood transfusion, we studied the survival of borrelia burgdorferi in blood products under blood bank storage conditions. two units of whole blood, separated into red cells (rbcs), fresh-frozen plasma (ffp), and platelet concentrates (pcs), were inoculated with b. burgdorferi (strain b31) in concentrations of approximately 3000 organisms per ml of rbcs and ffp ...	1989	2773025
lyme disease in northern california.		1989	2773475
lyme disease concurrent with human immunodeficiency virus infection.		1989	2773968
interstitial cystitis and borrelia burgdorferi.		1989	2774376
taking a second hard look at borrelia burgdorferi.		1989	2777700
rapid flow cytometric studies of borrelia burgdorferi phagocytosis by human polymorphonuclear leukocytes.	the interactions between a strain of borrelia burgdorferi and human polymorphonuclear leukocytes were studied by flow cytometry in the presence of specific or non-specific opsonizing factors. the capacity of the borrelias to stimulate leukocyte metabolism was also investigated. the results indicated that a low phagocytosis by isolated purified polymorphonuclear leukocytes did occur in the presence or absence of specific antibodies. within whole blood the percentages of phagocytosting leukocytes ...	1989	2777724
lyme disease: an elusive diagnosis.		2009	2778597
penetration of doxycycline into cerebrospinal fluid in patients treated for suspected lyme neuroborreliosis.	twelve patients were treated orally with 100 mg of doxycycline twice a day (b.i.d.) and 10 patients were treated with 200 mg b.i.d. for suspected tick-borne neuroborreliosis (lyme borreliosis). at 5 to 8 days after the start of therapy, the mean concentrations in serum were 4.7 micrograms/ml for the doxycycline dose of 100 mg b.i.d. and 7.5 micrograms/ml for 200 mg b.i.d., 2 to 3 h after the last drug administration. the corresponding levels for cerebrospinal fluid were 0.6 and 1.1 micrograms/ml ...	1989	2782858
lyme disease and migrating birds in the saint croix river valley.	during a study of migrating land birds in 1987, we examined over 9,200 individual birds representing 99 species from the saint croix river valley, a lyme disease-endemic area of east central minnesota and northwestern wisconsin. we found that 250 deer tick (ixodes dammini) larvae and nymphs infested 58 birds from 15 migrant species; 56 ticks (22.4%) were positive for the lyme disease spirochete borrelia burgdorferi. five ground-foraging migrant bird species favoring mesic habitats, veery (cathar ...	1989	2782872
[lyme borreliosis and its significance for the ent physician].	lyme disease is a tick-borne multisystemic borrelia infection to which the following diseases belong: erythema migrans, lymphadenosis benigna cutis, lymphocytic meningoradiculitis (bannwarth's syndrome), lyme-arthritis and acrodermitis chronica atrophicans. the infection rate of ticks with borrelia burgdorferi in germany amounts to 13.6% compared to the infection with the european spring summer meningoencephalitis virus with 1.1%. recent investigations show that lipopolysaccharides and interleuk ...	1989	2784972
[incidence and clinical spectrum of borrelia burgdorferi infection in spain. study group for lyme disease in spain].		1989	2786124
comparing the relative potential of rodents as reservoirs of the lyme disease spirochete (borrelia burgdorferi).	the authors compared the contribution of white-footed mice (peromyscus leucopus), chipmunks (tamias striatus), and meadow voles (microtus pennsylvanicus) to infection of vector ticks with the lyme disease spirochete, borrelia burgddorferi. at one massachusetts location where lyme disease is endemic, all three species of rodents were found to be infected. prevalence of infection, however, varied from 90% for mice, and 75% for chipmunks to just 5.5% for meadow voles. infectivity of these hosts for ...	1989	2787105
autoreactive t cells in rheumatic disease (1). analysis of growth frequencies and autoreactivity of t cells in patients with rheumatoid arthritis and lyme disease.	a limiting dilution system was established in order to estimate frequencies of interleukin-2 (il-2)-responsive, autoreactive and alloreactive t cells in samples of peripheral blood (pbl) and synovial fluid lymphocytes (sfl), from patients with rheumatoid arthritis (ra) and lyme disease, as well as from healthy donors and a patient with osteoarthrosis. the frequencies of il-2-dependent t-cell colony formation were significantly higher in patients with ra and lyme disease (median: 1/287) as compar ...	1989	2787645
lyme and other tick-borne diseases acquired in south carolina in 1988: a survey of 1,331 physicians.	2,346 primary care physicians were surveyed by mail to estimate the number of cases of tick-borne fever diagnosed by them during 1988. the results of the 57% response reveal 344 cases of rocky mountain spotted fever, 90 cases of lyme disease and 33 other tick-borne disease cases acquired in south carolina. the implications for a greater level of clinical awareness and a search for endemic vectors and animal hosts are emphasized.	1989	2788233
isolation of interleukin 1 from joint fluids of patients with lyme disease.	to investigate the role of interleukin 1 (il-1) in lyme arthritis we assayed synovial fluids (sf) for the presence of il-1 activity. crude sf from patients with lyme disease showed il-1-like activity. chromatography of joint fluids revealed activity at 15-20,000 daltons. two populations of cells were grown, which produced significant il-1 activity when stimulated with the lyme disease spirochete or its lipopolysaccharide. il-1 activity from sf or stimulated cells was neutralized with an antihuma ...	1989	2789287
lyme disease vector, ixodes dammini, identified in manitoba.		1989	2791076
unusual neurological manifestations of lyme disease: a case report.	we describe a case of lyme disease with a prolonged relapsing-remitting course, in which peripheral facial palsy, optic neuritis and myopathy were associated. after high-dose penicillin therapy the patient completely recovered.	1989	2793420
meningoencephalomyeloradiculoneuritis in one case of borrelia burgdorferi infection (lyme disease).	we describe a patient having serologically confirmed borrelia burgdorferi infection manifesting meningoencephalomyeloradiculoneuritis. the clinical and mri features suggested a multifocal vascular nervous system involvement. emg-eng showed abnormalities consistent with axonal degeneration initially involving the more proximal segments of the lower limb nerves.	1989	2793421
testing for borrelia burgdorferi.		1989	2793554
rheumatoid arthritis subsequent to borrelia burgdorferi infection in two dogs.	two dogs with clinical signs of polyarthritis developed rheumatoid arthritis subsequent to borrelia burgdorferi infection. in both dogs, the diagnosis of b burgdorferi infection was based on clinical signs of disease and high serum b burgdorferi titer. after antibiotic administration, both dogs had decreased b burgdorferi titer, but clinical response was temporary or was lacking. the dogs subsequently were rheumatoid factor-positive (antinuclear antibody- and anti-globulin-negative) and responde ...	1989	2793577
concurrent positive serology for ehrlichiosis and lyme disease.		1989	2794568
lyme disease--the great imitator.		1989	2794806
lyme disease: tick vectors, distribution, and reservoir hosts.		1989	2794809
clinical aspects of lyme disease.		1989	2794810
myositis during borrelia burgdorferi infection (lyme disease).	during the second stage of an illness caused by borrelia burgdorferi, a young woman developed a myopathic syndrome characterised by severe muscular pains, incapacitating weakness of the proximal limb and the neck, as well as the bulbar muscles and elevated serum ck levels. muscle biopsy revealed a non-inflammatory necrotising myopathy. b. burgdorferi infection was confirmed by a considerable rise of specific igg antibodies. a course of high dose steroids alleviated the myalgias, but paresis bega ...	1989	2795056
meningoradiculitis and encephalomyelitis due to borrelia burgdorferi: a follow-up study of 72 patients over 27 years.	in 1987, follow-up studies were conducted on 72 patients who had had meningoradiculitis and encephalomyelitis (8 patients) due to borrelia burgdorferi 5-27 years previously. these patients had not been treated with antibiotics, either during the acute disease or during the interval prior to follow-up studies. the patients had exhibited the typical symptoms of bannwarth's syndrome during the acute phase. at the follow-up studies, 33 patients showed no, and 23 only mild, clinical residual symptoms ...	1989	2795099
from the centers for disease control. lyme disease--united states, 1987 and 1988.		2009	2795796
from the centers for disease control. lyme disease--canada.		1989	2795797
[borrelia burgdorferi infection with bilateral optic neuritis and intracerebral demyelinization lesions].	in september, 1987, the authors saw a 25-year-old female patient with retinal perivasculitis, cystoid macular edema and papilledema in her right eye. the left eye was normal. visual acuity was 0.2 (od), 1.2 (os). after conventional infections had been ruled out systemic methylprednisolone therapy was instituted, but the patient's condition deteriorated. in may 1988 she presented with papilledema and a "neuroretinitis"-like finding in her left eye; in her right eye advanced optic nerve atrophy; v ...	1989	2796241
[acute borrelia burgdorferi encephalitis (lyme disease) in an algerian child].	a case of acute hemorrhagic leukoencephalitis is described in an algerian child with renal insufficiency that had been diagnosed at the terminal stage. convulsions, hemiplegia and consciousness disorders pointed to a necrotizing viral or bacterial form of encephalitis, but the definitive diagnosis was based on the detection of igm and igg specific serum antibodies raised against borrelia burgdorferi.	1989	2798000
[lyme disease in belgium: presence of the spirochete borrelia burgdorferi in ixodes ricinus ticks recovered from the meuse river region].		1989	2799146
[lyme disease].		2009	2799772
enzootic transmission of the agent of lyme disease in rabbits.	to determine whether cottontail rabbits (sylvilagus floridanus) maintain an enzootic cycle of transmission of the lyme disease spirochete (borrelia burgdorferi), we examined the prevalence of infection in ticks and rabbits in a location in which rabbits were abundant. of 72 unfed nymphal ixodes dentatus swept from vegetation, 32% were infected by this spirochete, as determined by darkfield microscopy and indirect immunofluorescence using monoclonal antibody h5332. infected ticks were reared from ...	1989	2802026
scintigraphic evaluation of lyme disease: gallium-67 imaging of lyme myositis.	a patient suffering from lyme disease had cardiac conduction abnormalities, symptoms of arthritis, and myalgia. a ga-67 image showed evidence of endomyocarditis, but intense skeletal muscle uptake pointed to lyme myositis. reference is made to two other case reports of lyme myositis.	1989	2805522
[facial palsy in lyme disease].	this paper reports twenty four cases of facial palsy in lyme disease for the first time in the forest region. most cases had history of tick bite. two strains of spirochete were isolated from the blood of 7 patients with facial palsy. these spirochetes were immunologically closely related to b. burgdorferi. eighteen serum samples of facial palsy were tested by indirect fluorescence assay, using b. burgdorferi b-31 as antigen. in serum, igg antibody titers of 1:64 to 1:2048 were found in 50% of t ...	1989	2805978
antibody response in white-footed mice (peromyscus leucopus) experimentally infected with the lyme disease spirochete (borrelia burgdorferi).	white-footed mice (peromyscus leucopus), the primary reservoir for borrelia burgdorferi in the northern midwest and northeastern united states, were experimentally inoculated with an infectious strain or a noninfectious strain of the lyme disease spirochete and examined for their specific antibody response with the enzyme-linked immunosorbent assay and western blot (immunoblot) analysis. immunoglobulin m (igm) anti-b. burgdorferi antibodies were detected in mice 1 to 2 days after inoculation wit ...	1989	2807530
biochemical and immunological characterization of the surface proteins of borrelia burgdorferi.	the immunodominant proteins and glycoproteins of borrelia burgdorferi were analyzed by one-dimensional (1d) and 2d gel electrophoresis. more than 100 polypeptide species could be detected on silver-stained 2d gels. separation of sonic extracts of the organism by differential centrifugation (100,000 x g) revealed several of the major proteins to reside predominantly within the pellet fraction. the antigenicity of the individual polypeptides was determined by western (immuno-) blot analysis with s ...	1989	2807540
the risk of borrelia burgdorferi infection is not increased in pet owners.		1989	2810640
lyme disease misdiagnosed as tmj syndrome. a case report.	due to the high incidence of lyme disease, the ease with which it can be misdiagnosed, and its potential for causing irreversible neurologic or cardiac complications and fatalities if left untreated, all patients living in known epidemic areas who manifest intractable facial pain, or what appears to be a case of temporomandibular joint syndrome that does not respond to therapy should be tested for lyme borelliosis. it should be remembered however, that not all patients with active lyme disease p ...	1989	2812630
lyme disease and other spirochetal diseases. proceedings of a symposium. washington, d.c., 29 february-1 march 1988.		2006	2814168
dermatologic manifestations of lyme disease.	erythema migrams (em), the distinctive cutaneous lesion of lyme disease, has a variable clinical appearance, but at some point presents as a centrifugally expanding, usually erythematous, annular patch. of 237 patients with this condition, 201 (85%) were examined initially from may through september. thirty-four (14%) remembered having been bitten by a deer tick. the median interval from the bite to the appearance of em was 9 days (range, 1-36 days). forty-one (17%) of the patients had multiple ...	1989	2814169
clinical pathologic correlations of lyme disease.	the multisystem effects caused by borrelia burgdorferi in lyme disease are multiple, varied, and unpredictable. in some patients, the full extent of the infection consists of a stage i acute systemic viral-like illness. stage ii primarily involves the cardiovascular system (myocarditis) and/or the central nervous system (cns) (meningoencephalitis, polyradiculitis). more inflammatory cells are found in the heart and nervous system structures during this intermediate stage than are found in any ti ...	1989	2814170
[lyme disease: an infection with localization in various organs].		1987	2821410
immunochemical characterization of and isolation of the gene for a borrelia burgdorferi immunodominant 60-kilodalton antigen common to a wide range of bacteria.	by crossed immunoelectrophoresis and western blotting (immunoblotting), it was shown that borrelia burgdorferi expresses the 60-kilodalton common antigen (ca) that is cross-reactive with an equivalent antigen in a wide range of remotely related bacteria. b. burgdorferi ca is strongly immunogenic. a b. burgdorferi genomic library was constructed by using a plasmid cloning system. escherichia coli recombinants were screened for expression of immunodominant b. burgdorferi antigens. one of the recom ...	1988	2840400
borrelia burgdorferi infection: a neurologist's perspective.		1988	2847620
clinical pathologic correlations of lyme disease by stage.	lyme disease is capable of producing a wide variety of clinical pathologic conditions and lesions having in common histologic features of collagen-vascular disease. the plasma cell is an omnipotent inflammatory responder in most tissues involved by lyme disease, ranging from relatively acute to lesions that have gone on for years. vascular thickening also seems to be prominent, and in the dermis is accompanied by scleroderma-like collagen expansion. the disease in some ways resembles the respons ...	1988	2847622
differences between lyme disease and european arthropod-borne borrelia infections.		1985	2857456
meningoradiculitis associated with infection by borrelia burgdorferi.		1985	2861356
lyme disease in patients previously suspected of arbovirus infection.		1985	2861536
meningoradiculitis associated with infections by borrelia burgdorferi.		1985	2862333
serology of lyme disease.		1986	2869276
myocarditis associated with tickborne borrelia burgdorferi infection.		1986	2872445
the etiologic agent of lyme disease in deer flies, horse flies, and mosquitoes.		1986	2873190
multiple sclerosis and borrelia burgdorferi.		1986	2875306
spirochaetes, lyme disease, and multiple sclerosis.		1986	2876151
reinfection with borrelia burgdorferi.		1986	2877167
acute transverse myelitis as presenting neurological feature of lyme disease.		2010	2877361
spirochaetes and lyme disease.		1986	2877362
emerging pattern of lyme disease in the united kingdom and irish republic.	in the past year there have been 68 cases of lyme disease in the united kingdom and republic of ireland. 41 patients had erythema chronicum migrans, and 8 of them had associated neurological disease. 13 further patients presented with neurological disease without a preceding skin lesion. myocarditis was present in 1 patient. ixodes ricinus was confirmed as the vector for lyme disease. in two areas deer were found to be infected by borrelia burgdorferi, the causative organism of lyme disease. 86% ...	1987	2880076
lyme disease in europe and north america.		1987	2882096
severe encephalopathy associated with lyme disease.		1987	2882097
antibodies to borrelia burgdorferi and localised scleroderma.		1987	2882098
horse reservoir for borrelia burgdorferi?		1987	2882362
arthritis as manifestation of lyme disease in england.		2010	2884430
shulman syndrome, a scleroderma subtype caused by borrelia burgdorferi?		1987	2885476
lyme disease in europe.		1987	2886728
borrelia burgdorferi antibodies and amyotrophic lateral sclerosis.		1987	2886788
granulomatous hepatitis associated with lyme disease.		1987	2887904
borrelia burgdorferi and shulman syndrome.		1987	2887905
mild lyme disease.		1988	2896854
treatment of late lyme borreliosis--randomised comparison of ceftriaxone and penicillin.	23 patients with clinically active late lyme disease were randomly assigned to intravenous treatment with either penicillin or ceftriaxone. of the 10 treated with penicillin, 5 were judged treatment failures; of the 13 who received ceftriaxone, only 1 did not respond. an additional 31 patients were subsequently treated with ceftriaxone 4 g/day (n = 17) or 2 g/day (n = 14); success rates in both groups were comparable to those in the cohort randomised to ceftriaxone. patients unresponsive to ceft ...	1988	2897008