Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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| using phenotype microarrays in the assessment of the antibiotic susceptibility profile of bacteria isolated from wastewater in on-site treatment facilities. | the scope of the study was to apply phenotype biolog microarray (pm) technology to test the antibiotic sensitivity of the bacterial strains isolated from on-site wastewater treatment facilities. in the first step of the study, the percentage values of resistant bacteria from total heterotrophic bacteria growing on solid media supplemented with various antibiotics were determined. in the untreated wastewater, the average shares of kanamycin-, streptomycin-, and tetracycline-resistant bacteria wer ... | 2017 | 28451946 |
| antimicrobial efficacy of contact lens care solutions against neutrophil-enhanced bacterial biofilms. | neutrophil-derived extracellular debris has been shown to accelerate bacterial biofilm formation on hydrogel and silicone hydrogel contact lens surfaces compared to lenses inoculated with bacteria alone. the purpose of this study was to evaluate the disinfection efficacy of four standard commercial contact lens cleaning regimens against neutrophil-enhanced bacterial biofilms formed on silicone hydrogel contact lenses. | 2017 | 28473944 |
| the prevalence of antibiotic-resistant bacteria (arb) in waters of the lower ballona creek watershed, los angeles county, california. | screening for the prevalence of antibiotic-resistant bacteria (arb) was done at the ballona creek and wetlands, an urban-impacted wetland system in los angeles, california. the goals were (1) to assess the overall prevalence of arb, and (2) compare differences in arb abundance and the types of antibiotic resistance (ar) among the following sample types: lagoon water from del rey lagoon, urban runoff from ballona creek, and water from the ballona wetlands (tidal water flooding in from the adjacen ... | 2017 | 28488226 |
| optimization of prodigiosin production by serratia marcescens using crude glycerol and enhancing production using gamma radiation. | prodigiosin is a red pigment produced by serratia marcescens. prodigiosin is regarded as a promising drug owing to its reported characteristics of possessing anti-microbial, anti-cancer, and immunosuppressive activity. a factorial design was applied to generate a set of 32 experimental combinations to study the optimal conditions for pigment production using crude glycerol obtained from local biodiesel facility as carbon source for the growth of serratia marcescens. the maximum production (870 u ... | 2017 | 28491819 |
| draft genome sequences of serratia marcescens strains caprex sy13 and caprex sy21 isolated from yams. | serratia marcescens strains caprex sy13 and caprex sy21 were isolated from ghanaian yams from a london market. the draft genomes suggest that the strains are similar, with genomes of 5,308,004 and 5,157,134 bp and 59.35 and 59.62 g+c%, respectively. the genes necessary for prodigiosin biosynthesis were present in both strains. | 2017 | 28495763 |
| new prodigiosin derivatives obtained by mutasynthesis in pseudomonas putida. | the deeply red-colored natural compound prodigiosin is a representative of the prodiginine alkaloid family, which possesses bioactivities as antimicrobial, antitumor, and antimalarial agents. various bacteria including the opportunistic human pathogen serratia marcescens and different members of the streptomycetaceae and pseudoalteromonadaceae produce prodiginines. in addition, these microbes generally accumulate many structurally related alkaloids making efficient prodiginine synthesis and puri ... | 2017 | 28505410 |
| cross-talk between bacterial two-component systems drives stepwise regulation of flagellar biosynthesis in swarming development. | swarming motility is a mode of bacterial movement over a solid surface driven by rotating flagella in a coordinated manner. bacteria can use two-component system (tcs), which typically comprises a sensor kinase and a specific cognate response regulator, to properly react to environmental changes. we previously showed that the tcs rssab suppresses flagellar biosynthesis master regulator flhdc specifically in swarming lag phase to control surface migration timing without affecting expansion rate i ... | 2017 | 28522292 |
| tetrameric structure of the flagellar cap protein flid from serratia marcescens. | bacterial motility is provided by the flagellum. flid is located at the distal end of the flagellum and plays a key role in the insertion of each flagellin protein at the growing tip of the flagellar filament. because flid functions as an oligomer, the determination of the oligomeric state of flid is critical to understanding the molecular mechanism of flid-mediated flagellar growth. flid has been shown to adopt a pentameric or a hexameric structure depending on the bacterial species. here, we r ... | 2017 | 28527888 |
| synthesis of 1,4-oxazepane-2,5-diones via cyclization of rotationally restricted amino acid precursors and structural reassignment of serratin. | several natural products containing a 1,4-oxazepane-2,5-dione-core are known. one example is serratin, isolated from serratia marcescens. because of the presence of a carboxylic amide, which has a preference for a trans-conformation, and the presence of a labile lactone in this core, many synthetic methodologies commonly used for the cyclization toward medium-sized heterocycles cannot be applied. as n-acyl amino acids lacking a third substituent at nitrogen failed to undergo ring-closure, severa ... | 2017 | 28530397 |
| insect pathogenic fungus interacts with the gut microbiota to accelerate mosquito mortality. | the insect gut microbiota plays crucial roles in modulating the interactions between the host and intestinal pathogens. unlike viruses, bacteria, and parasites, which need to be ingested to cause disease, entomopathogenic fungi infect insects through the cuticle and proliferate in the hemolymph. however, interactions between the gut microbiota and entomopathogenic fungi are unknown. here we show that the pathogenic fungus beauveria bassiana interacts with the gut microbiota to accelerate mosquit ... | 2017 | 28533370 |
| efficient whole-cell biocatalyst for 2,3-butanediol/acetoin production with nadh/nad(+) regeneration system in engineered serratia marcescens. | serratia marcescens is reported to possess the potential for industrial 2,3-butanediol or acetoin production by fermentation. but 2,3-butanediol or acetoin are always co-produced and this may make purification process difficult. so biocatalytic technologies may be the appropriate production methods. in this study, we developed an auto-inducing expression system based on pet system and swr quorum sensing system by using s. marcescens. by using this system, s. marcescens could be engineered as who ... | 2017 | 28535612 |
| capsule production and glucose metabolism dictate fitness during serratia marcescens bacteremia. | serratia marcescens is an opportunistic pathogen that causes a range of human infections, including bacteremia, keratitis, wound infections, and urinary tract infections. compared to other members of the enterobacteriaceae family, the genetic factors that facilitate serratia proliferation within the mammalian host are less well defined. an in vivo screen of transposon insertion mutants identified 212 s. marcescens fitness genes that contribute to bacterial survival in a murine model of bloodstre ... | 2017 | 28536292 |
| biosynthesis of zno nanoparticles by a new pichia kudriavzevii yeast strain and evaluation of their antimicrobial and antioxidant activities. | the potential ability of a new yeast strain, pichia kudriavzevii, in the synthesis of zinc oxide nanoparticles (zno-nps) through a green method was explored in this study. the effect of reaction time (12, 24 and 36 h) on the structure of the resulting zno nanoparticles was investigated. from the xrd and tem results, the zno-nps with a hexagonal wurtzite structure and a particle crystal size of ~10-61 nm was formed at different reaction times. combing xrd, tem, and pl results, it was revealed tha ... | 2017 | 28538674 |
| crystal structure of the sensor domain of baes from serratia marcescens fs14. | the sensor histidine kinases of two-component signal-transduction systems (tcss) are essential for bacteria to adapt to variable environmental conditions. the two-component regulatory system baes/r increases multidrug and metal resistance in salmonella and escherichia coli. in this study, we report the x-ray structure of the periplasmic sensor domain of baes from serratia marcescens fs14. the baes sensor domain (34-160) adopts a mixed α/β-fold containing a central four-stranded antiparallel β-sh ... | 2017 | 28544098 |
| cysteine biosynthesis controls serratia marcescens phospholipase activity. | serratia marcescens causes health care-associated opportunistic infections that can be difficult to treat due to a high incidence of antibiotic resistance. one of the many secreted proteins of s. marcescens is the phla phospholipase enzyme. genes involved in the production and secretion of phla were identified by screening a transposon insertion library for phospholipase-deficient mutants on phosphatidylcholine-containing medium. mutations were identified in four genes (cyaa, crp, flij, and flip ... | 2017 | 28559296 |
| antibiotic resistance and virulence phenotypes of recent bacterial strains isolated from urinary tract infections in elderly patients with prostatic disease. | acute bacterial prostatitis is one of the frequent complications of urinary tract infection (uti). from the approximately 10% of men having prostatitis, 7% experience a bacterial prostatitis. the purpose of this study was to investigate the prevalence of uropathogens associated with utis in older patients with benign prostatic hyperplasia and to assess their susceptibility to commonly prescribed antibiotics as well as the relationships between microbial virulence and resistance features. uropath ... | 2017 | 28561794 |
| ozone sensitivity and catalase activity in pigmented and non-pigmented strains of serratia marcescens. | ozone exposure rapidly leads to bacterial death, making ozone an effective disinfectant in food industry and health care arena. however, microbial defenses may moderate this effect and play a role in the effective use of oxidizing agents for disinfection. serratia marcescens is an opportunistic pathogen, expressing genes differentially during infection of a human host. a better understanding of regulatory systems that control expression of serratia's virulence genes and defenses is therefore val ... | 2017 | 28567147 |
| [implication of a national outbreak of serratia marcescens associated with a contaminated solution of chlorhexidine in a paediatric hospital]. | 2017 | 28571897 | |
| neonicotinoid-induced pathogen susceptibility is mitigated by lactobacillus plantarum immune stimulation in a drosophila melanogaster model. | pesticides are used extensively in food production to maximize crop yields. however, neonicotinoid insecticides exert unintentional toxicity to honey bees (apis mellifera) that may partially be associated with massive population declines referred to as colony collapse disorder. we hypothesized that imidacloprid (common neonicotinoid; imi) exposure would make drosophila melanogaster (an insect model for the honey bee) more susceptible to bacterial pathogens, heat stress, and intestinal dysbiosis. ... | 2017 | 28578396 |
| adult bacterial exposure increases behavioral variation and drives higher repeatability in field crickets. | among-individual differences in behavior are now a widely studied research-focus within the field of behavioral ecology. furthermore, elements of an animal's internal state, such as energy or fat reserves, and infection status can have large impacts on behaviors. despite this, we still know little regarding how state may affect behavioral variation. recent exposure to pathogens may have a particularly large impact on behavioral expression given that it likely activates costly immune pathways, po ... | 2016 | 28584393 |
| association between pathogens from tracheal aspirate and oral biofilm of patients on mechanical ventilation. | the aim of this study was to detect possible associations between respiratory pathogens from tracheal aspirate and oral biofilm samples in intubated patients in an intensive care unit (icu), and to identify the most common respiratory pathogens in oral biofilm, particularly in patients that developed ventilator-associated pneumonia (vap). two oral biofilm samples were collected from the tongue of intubated patients (at admission and after 48 hours) and analyzed by culture with the antibiotic sen ... | 2017 | 28591237 |
| combination antimicrobial therapy for bacterial infections : guidelines for the clinician. | therapy with antimicrobial combinations has been used as long as antimicrobials have been available. combinations of antibiotics are often used to take advantage of different mechanisms of action and/or toxicity profiles. well established indications for combination antimicrobial therapy include: (a) empirical treatment of life-threatening infections; (b) treatment of polymicrobial infections; (c) prevention of the emergence of bacterial resistance; and (d) for synergism. disadvantages of combin ... | 1996 | 28593588 |
| genome sequence of serratia marcescens phage bf. | phages infecting serratia marcescens, a common causative agent of nosocomial infections, have potential therapeutic applications. here, we report the complete genome of the novel s. marcescens phage bf, representing the third-largest phage genome sequenced to date. | 2017 | 28596386 |
| innate immune system capabilities of the asian citrus psyllid, diaphorina citri. | citrus production worldwide is currently threatened by huanglongbing, or citrus greening disease. the associated pathogen, candidatus liberibacter asiaticus (clas), is transmitted by the asian citrus psyllid, diaphorina citri. annotation of the d. citri genome revealed a reduced innate immune system lacking a number of antimicrobial peptides and the imd pathway associated with defense against gram-negative bacteria. we characterized this apparent immune reduction in survival assays in which d. c ... | 2017 | 28624621 |
| bacterial contamination in physical therapy departments in the state of kuwait. | [purpose] interferential therapy and electrical stimulation are electrophysical modalities commonly used in physical therapy departments to treat patients with musculoskeletal problems. these machines are applied directly to the patient's skin via a medium or electrodes, which can facilitate the transmission of microorganisms from one patient to another. the purpose of this study was to determine the extent of microorganism contamination in the machines sponges at physical therapy departments in ... | 2017 | 28626312 |
| imipenem/cilastatin : a reappraisal of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy. | imipenem is an antibacterial agent of the carbapenem class of β-lactams, with a very broad spectrum of activity that includes most gram-negative and gram-positive pathogens, aerobes and anaerobes, and with marked activity against species producing β-lactamases. it is coadministered with cilastatin, a renal dehydropeptidase inhibitor that prevents renal metabolism of imipenem. as initial monotherapy, imipenem/cilastatin provides effective and well-tolerated treatment of moderate to severe infecti ... | 1992 | 28634918 |
| genomic and phenotypic characterisation of fluoroquinolone resistance mechanisms in enterobacteriaceae in durban, south africa. | resistance to fluoroquinolones (fq) is being increasingly reported and found to be mediated by efflux pumps, plasmid-mediated quinolone resistance genes (pmqr) and mutations in gyra, gyrb, parc and pare. however, studies reporting on fq resistance mechanisms (fqrm), particularly in africa, are focused mostly on salmonella. this study used a whole-genome-based approach to describe fqrm in forty-eight clinical enterobacteriaceae isolates comprising of klebsiella pneumoniae (n = 21), serratia marce ... | 2017 | 28636609 |
| the antimicrobial spectrum of xeroform(®). | xeroform(®) is a petrolatum-based fine mesh gauze containing 3% bismuth tribromophenate. bismuth, similar to other metals, has antimicrobial properties. xeroform(®) has been used for decades in burn and plastic surgery as a donor site dressing and as a covering for wounds or partial thickness burns. despite this, the antimicrobial spectrum of xeroform(®) remains largely unknown. we examined the in-vitro efficacy of xeroform(®) against common burn pathogens using zone-of-inhibition methodology in ... | 2017 | 28641915 |
| lower-extremity infections caused by serratia marcescens a report of three cases and a literature review. | serratia marcescens is a ubiquitous, facultatively anaerobic, gram-negative bacillus that has been cited to cause infection in immunocompromised populations. in the literature, s marcescens infections of the lower extremity have presented as granulomatous ulceration, abscess, bullous cellulitis, and necrotizing fasciitis. herein we present a series of three cases of lower-extremity infections in which s marcescens was the sole or a contributing pathogen. we discuss the commonalities of these thr ... | 2017 | 28650753 |
| host mating system and coevolutionary dynamics shape the evolution of parasite avoidance in caenorhabditis elegans host populations. | hosts exhibit a variety of defence mechanisms against parasites, including avoidance. both host-parasite coevolutionary dynamics and the host mating system can alter the evolutionary trajectories of populations. does the nature of host-parasite interactions and the host mating system affect the mechanisms that evolve to confer host defence? in a previous experimental evolution study, mixed mating and obligately outcrossing caenorhabditis elegans host populations adapted to either coevolving or s ... | 2017 | 28655368 |
| draft genome sequence of a multidrug-resistant serratia marcescens strain, isolated from a patient with peritoneal cancer in south africa. | we report here the draft genome sequence of serratia marcescens ml2637, isolated from a south african pediatric patient in the intensive care unit with peritoneal cancer. the genome comprised 5,718,350 bp, with a 59.1% g+c content. there were 5,594 predicted genes, including 5,301 protein-coding genes, 199 pseudogenes, and 94 rna genes. | 2017 | 28663295 |
| community-acquired cutaneous ulcer in a child caused by serratia marcescens. | serratia marcescens is a gram-negative, aerobic, motile bacillus belonging to the family enterobacteriaceae. s. marcescens has been implicated in different types of infections including urinary tract infection, septicaemia, meningitis and wound infections. very few cases of skin infections caused by this organism have been reported in the medical literature. s. marcescens is an important nosocomial pathogen but has rarely been implicated as a cause of community-acquired soft-tissue infections. | 2014 | 28663809 |
| quantitative determination of anti-bacterial activity during bacterial co-culture. | anti-bacterial activity assays are an important tool in the assessment of the ability of one bacterium to kill or inhibit the growth of another, for example during the study of the type vi secretion system (t6ss) and the anti-bacterial toxins it secretes. the method we describe here can detect the ability of a bacterial strain to kill or inhibit other bacterial cells in a contact-dependent manner when co-cultured on an agar surface. it is particularly useful since it enumerates the recovery of v ... | 2017 | 28667634 |
| a rare case of community acquired serratia lung abscess in a patient with cardiac bronchus. | the incidence of lung abscess caused by serratia marcescens is extremely low and is only reported in the immunocompromised population. we present a previously healthy woman with serratia lung abscess in close proximity with an accessory cardiac bronchus. the patient was treated with appropriate antibiotics which led to complete resolution of the lesion. our case highlights that individuals without medical co-morbidities may develop atypical lung infections like serratia when associated with anat ... | 2017 | 28667656 |
| mass transfer kinetics of biosorption of nitrogenous matter from palm oil mill effluent by aerobic granules in sequencing batch reactor. | understanding of mass transfer kinetics is important for biosorption of nitrogen compounds from palm oil mill effluent (pome) to gain a mechanistic insight into future biological processes for the treatment of high organic loading wastewater. in this study, the rates of global and sequential mass transfer were determined using the modified mass transfer factor equations for the experiments to remove nitrogen by aerobic granular sludge accumulation in a sequencing batch reactor (sbr). the maximum ... | 2017 | 28675960 |
| serratia marcescens bacteremia: nosocomial cluster following narcotic diversion. | objective to describe the investigation and control of a cluster of serratia marcescens bacteremia in a 505-bed tertiary-care center. methods cluster cases were defined as all patients with s. marcescens bacteremia between march 2 and april 7, 2014, who were found to have identical or related blood isolates determined by molecular typing with pulsed-field gel electrophoresis. cases were compared using bivariate analysis with controls admitted at the same time and to the same service as the cases ... | 2017 | 28679460 |
| regulation of p53 and survivin by prodigiosin compound derived from serratia marcescens contribute to caspase-3-dependent apoptosis in acute lymphoblastic leukemia cells. | tumor suppressor p53 and proto-oncogene survivin are challenging targets for anticancer drugs in acute lymphoblastic leukemia (all) which are associated with chemoresistance. yet, no p53 and survivin-modulating drug with low toxicity and high efficacy has been approved for clinical application in all. consequently, the search for novel compounds which target p53 or survivin is needed to further advance all treatment. prodigiosin, a secondary metabolite of serratia marcescens induces apoptosis in ... | 2017 | 28681618 |
| tnseqdiff: identification of conditionally essential genes in transposon sequencing studies. | tn-seq is a high throughput technique for analysis of transposon mutant libraries to determine conditional essentiality of a gene under an experimental condition. a special feature of the tn-seq data is that multiple mutants in a gene provides independent evidence to prioritize that gene as being essential. the existing methods do not account for this feature or rely on a high-density transposon library. moreover, these methods are unable to accommodate complex designs. | 2017 | 28683752 |
| inhibitory growth of oral squamous cell carcinoma cancer via bacterial prodigiosin. | chemotherapy drugs for oral cancers always cause side effects and adverse effects. currently natural sources and herbs are being searched for treated human oral squamous carcinoma cells (oscc) in an effort to alleviate the causations of agents in oral cancers chemotherapy. this study investigates the effect of prodigiosin (pg), an alkaloid and natural red pigment as a secondary metabolite of serratia marcescens, to inhibit human oral squamous carcinoma cell growth; thereby, developing a new drug ... | 2017 | 28714874 |
| antimicrobial resistance patterns of gram-negative bacteria isolated from bloodstream infections in an iranian referral pediatric hospital: a six-year study. | bloodstream infections (bsis) are considered as a major cause of morbidity and mortality in children all over the world. the aim of this study was to describe the epidemiology and antimicrobial resistance patterns of gram-negative bacteria (gnb) isolated from bloodstream infections (bsis) in children admitted to the children medical center hospital (cmc), tehran, iran. | 2017 | 28729206 |
| synthesis and characterization of nanoparticles conjugated tannase and using it for enhancement of antibacterial activity of tannase produced by serratia marcescens. | fourteen isolates of serratia marcescens were collected from patients suffering from septicemia. all theseisolates revealed different levels in tannase production. tannase was partially purified from serratia marcescens b9 by precipitation method at 70% saturation of ammonium sulfate. au, pt, sno2 and sio2 nanoparticles were prepared by laser ablation and examined by transmission electron microscopy (tem), x-ray diffraction pattern and uv-visible absorption spectroscopy. conjugation of sio2 nano ... | 2017 | 28735079 |
| an unusual case of acute parotitis in a young adult. | acute bacterial parotitis is uncommon in young adults. infection with serratia marcescens is even rarer and usually found in hospitalized patients. this case report focuses on a young woman with acute bacterial parotitis caused by s. marcescens that required a longer-than-normal course of antibiotics. | 2017 | 28742741 |
| cyclohexene-fused 1,3-oxazines with selective antibacterial and antiparasitic action and low cytotoxic effects. | oxazine derivatives, a class of heterocyclic compounds, exhibit a variety of biological properties, such as anticonvulsant and antitumor activities. in this study, we evaluated the effect of two cyclohexene-fused 1,3-oxazines (cis‑1-benzyl-n-phenyl-1,4,4a,5,8,8a-hexahydro-3,1-benzoxazin-2-imine (1) and trans‑n-phenyl-1,4,4a,5,8,8a-hexahydro-3,1-benzoxazin-2-imine (2)) in cultures of bacillus cereus, enterococcus faecalis, escherichia coli, klebsiella pneumoniae, salmonella enterica, serratia mar ... | 2017 | 28755871 |
| biological activities and secondary metabolite screening of rumex hastatus extract through fourier transform infrared and raman spectroscopy. | human infectious diseases began by various pathogens including bacteria, fungi, viruses, parasites, and protozoans. these infectious agents are controlled by using synthetic drugs as well as natural sources. | 2017 | 28758575 |
| isolation of vanadium-resistance endophytic bacterium pre01 from pteris vittata in stone coal smelting district and characterization for potential use in phytoremediation. | this study investigates the v-resistant endophytic bacteria isolated from v-accumulator pteris vittata grown on stone coal smelting district. among all the ten isolates, the strain pre01 identified as serratia marcescens ss marcescens by biolog gen iii microplate™ was screened out by ranking first in terms of heavy metal resistance and plant growth promoting traits. the s. marcescens pre01 had strong v, cr and cd resistance especially for v up to 1500mg/l. in addition, it exhibited acc deaminase ... | 2017 | 28759788 |
| protein engineering and homologous expression of serratia marcescens lipase for efficient synthesis of a pharmaceutically relevant chiral epoxyester. | the lipase isolated from serratia marcescens (lipa) is a useful biocatalyst for kinetic resolution of a pharmaceutically relevant epoxyester, (±)-3-(4'-methoxyphenyl) glycidic acid methyl ester [(±)-mpgm], to afford optically pure (-)-mpgm, a key intermediate for the synthesis of diltiazem hydrochloride. two mutants, lipal315s and lipas271f, were identified from the combinatorial saturation mutation library of 14 amino acid residues lining the substrate-binding pocket. lipal315s, lipas271f, and ... | 2017 | 28766104 |
| resistance phenotypes and susceptibility of contemporary serratia isolates in the university hospital of crete, greece. | to study changes in the susceptibility of serratia spp. in crete, greece (2010-2015). | 2017 | 28768448 |
| inactivation of the major hemolysin gene influences expression of the nonribosomal peptide synthetase gene swra in the insect pathogen serratia sp. strain scbi. | hemolysins are important virulence factors for many bacterial pathogens, including serratia marcescens the role of the major hemolysin gene in the insect pathogen serratia sp. scbi was investigated using both forward and reverse genetics approaches. introduction of the major hemolysin gene into escherichia coli resulted in a gain of both virulence and hemolytic activity. inactivation of this hemolysin in serratia sp. scbi resulted in loss of hemolysis, but did not attenuate insecticidal activity ... | 2017 | 28784817 |
| multi-effect of the water-soluble moringa oleifera lectin against serratia marcescens and bacillus sp.: antibacterial, antibiofilm and anti-adhesive properties. | to evaluate the antibiofilm potential of water-soluble moringa oleifera seed lectin (wsmol) on serratia marcescens and bacillus sp. | 2017 | 28792661 |
| evolution of caenorhabditis elegans host defense under selection by the bacterial parasite serratia marcescens. | parasites can impose strong selection on hosts. in response, some host populations have adapted via the evolution of defenses that prevent or impede infection by parasites. however, host populations have also evolved life history shifts that maximize host fitness despite infection. outcrossing and self-fertilization can have contrasting effects on evolutionary trajectories of host populations. while selfing and outcrossing are known to affect the rate at which host populations adapt in response ... | 2017 | 28792961 |
| multi-fractal characterization of bacterial swimming dynamics: a case study on real and simulated serratia marcescens. | to add to the current state of knowledge about bacterial swimming dynamics, in this paper, we study the fractal swimming dynamics of populations of serratia marcescens bacteria both in vitro and in silico, while accounting for realistic conditions like volume exclusion, chemical interactions, obstacles and distribution of chemoattractant in the environment. while previous research has shown that bacterial motion is non-ergodic, we demonstrate that, besides the non-ergodicity, the bacterial swimm ... | 2017 | 28804259 |
| a comparative study of the adhesion of biosynthesized gold and conjugated gold/prodigiosin nanoparticles to triple negative breast cancer cells. | this paper explores the adhesion of biosynthesized gold nanoparticles (aunps) and gold (au) nanoparticle/prodigiosin (pg) drug nanoparticles to breast cancer cells (mda-mb-231 cells). the aunps were synthesized in a record time (less than 30 s) from nauclea latifolia leaf extracts, while the pg was produced via bacterial synthesis with serratia marcescens sp. the size distributions and shapes of the resulting aunps were characterized using transmission electron microscopy (tem), while the result ... | 2017 | 28819929 |
| a transcriptional regulatory mechanism finely tunes the firing of type vi secretion system in response to bacterial enemies. | the ability to detect and measure danger from an environmental signal is paramount for bacteria to respond accordingly, deploying strategies that halt or counteract potential cellular injury and maximize survival chances. type vi secretion systems (t6sss) are complex bacterial contractile nanomachines able to target toxic effectors into neighboring bacteria competing for the same colonization niche. previous studies support the concept that either t6sss are constitutively active or they fire eff ... | 2017 | 28830939 |
| pseudomonas aeruginosa exla and serratia marcescens shla trigger cadherin cleavage by promoting calcium influx and adam10 activation. | pore-forming toxins are potent virulence factors secreted by a large array of bacteria. here, we deciphered the action of exla from pseudomonas aeruginosa and shla from serratia marcescens on host cell-cell junctions. exla and shla are two members of a unique family of pore-forming toxins secreted by a two-component secretion system. bacteria secreting either toxin induced an exla- or shla-dependent rapid cleavage of e-cadherin and ve-cadherin in epithelial and endothelial cells, respectively. c ... | 2017 | 28832671 |
| antimicrobial properties of silver cations substituted to faujasite mineral. | a goal of our study was to find an alternative to nano-silver-based antimicrobial materials which would contain active silver immobilized in a solid matrix that prevents its migration into the surrounding environment. in this study, we investigated whether silver cations dispersed in an atomic form and trapped in an ion-exchanged zeolite show comparable antimicrobial activity to silver nanoparticles (nps). the biocidal active material was prepared from the sodium form of faujasite type zeolite i ... | 2017 | 28846614 |
| widespread fosfomycin resistance in gram-negative bacteria attributable to the chromosomal fosa gene. | fosfomycin is a decades-old antibiotic which is being revisited because of its perceived activity against many extensively drug-resistant gram-negative pathogens. fosa proteins are mn(2+) and k(+)-dependent glutathione s-transferases which confer fosfomycin resistance in gram-negative bacteria by conjugation of glutathione to the antibiotic. plasmid-borne fosa variants have been reported in fosfomycin-resistant escherichia coli strains. however, the prevalence and distribution of fosa in other g ... | 2017 | 28851843 |
| the risk of cardiac device-related infection in bacteremic patients is species specific: results of a 12-year prospective cohort. | the species-specific risk of cardiac device-related infection (cdri) among bacteremic patients is incompletely understood. | 2017 | 28852678 |
| amycolatopsis acidiphila sp. nov., a moderately acidophilic species isolated from coal mine soil. | little is known on members of the genus amycolatopsis inhabiting acidic habitats. in this study, a moderately acidophilic amycolatopsis strain, designated 2-5t, was isolated from coal mine soil, and subjected to a polyphasic taxonomic characterization. analysis based on 16s rrna gene sequences indicated that the strain was most closely related to the type strain of amycolatopsis bartoniae, sharing 99.30 % similarity, while similarity to all other amycolatopsis species was less than 97 %. the dna ... | 2017 | 28857027 |